COVID-19 Evidence Reviews
as of 2/26/21
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Today's Feature


2/24/2021
The NIH COVID-19 Treatment Guidelines Panel have issued a statement on the EUA of bamlanivimab plus etesevimab combination for the treatment of mild to moderate COVID-19.



Completed Reviews
 
= living review
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
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2/26/21
Tan BK, Mainbourg S, Friggeri A, et al. | Thorax
Aim: To review the evidence on the prevalence of venous thromboembolic event (VTE) and arterial thromboembolic event (ATE) thromboembolic events in patients with COVID-19.
RECENTLY UPDATED
2/26/21
Ernawati K, Cantika IB, Isaputri RR, et al. | Int J Public Health Sci
Aim: To determine the community's knowledge, attitudes, and behavior in preventing the transmission of COVID-19.
2/26/21
Aibakr AA, Ingle NA, Assery MK, et al. | Ann Med Health Sci Res
Aim: To identify the role of corticosteroids on coronavirus infection and to compare the mortality and morbidity rate of steroid intervened corona virus infected patients.
2/26/21
Sun C, Chen Y, Hu L, et al.  | Dig Dis Sci
Aim: To assess effects of famotidine on improving the outcome of those suffered COVID-19.
RECENTLY UPDATED
2/26/21
Mishra P, Parveen R, Bajpai R, et al. | Ann Acad Med Singap
Aim: To find the probable association between cardiovascular disease with disease severity and mortality in COVID-19 patients.
2/26/21
Bentivegna M, Hulme C, Ebell MH | J Am Board Fam Med
Aim: To summarize the best available evidence regarding individual risk factors, simple risk scores, and multivariate models that use patient characteristics, vital signs, comorbidities, and laboratory tests in inpatients.
RECENTLY UPDATED
2/26/21
Benzinger P, Kuru S, Keilhauer A, et al. | Z Gerontol Geriatr
Aim: To review the evidence on the psychosocial effects of the COVID-19 pandemic on residents, visitors, and employees of elderly care facilities.
2/26/21
Hurtado-Diaz M, de la Cruz JC, Blanco-Munoz J, et al. | Salud Publica de Mexico
Aim: To summarize and analyze the evidence of the association between Covid-19 and climatic factors. 
2/25/21
Zhang H, Ma S, Han T, et al. | Eur J Integr Med
Aim: To review the evidence on the influence of smoking history on the severe and critical outcomes on people with COVID-19 pneumonia.
2/25/21
McAlpine LS, Fesharaki-Zadeh A, Spusich S | Curr Opin Psychiatry
Aim: To review the outcomes in patients with COVID-19 and NDD.
2/25/21
Yin TX, Li Y, Ying Y, et al. | BMC Infect Dis
Aim: To provide systematic evaluation and detailed estimation of prevalence rates of different kinds of common comorbidities in severe and non-severe COVID-19 patients and tries to illustrate the outcomes by combination with underlying pathogenesis to better understand how basic diseases contribute to the aggravation of SARS-CoV-2 infection.
RECENTLY UPDATED
2/25/21
Struyf T, Deeks JJ, Dinnes J et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of signs and symptoms to determine if a person presenting in primary care or to hospital outpatient settings, such as the emergency department or dedicated COVID?19 clinics, has COVID?19 disease or COVID?19 pneumonia.
RECENTLY UPDATED
DIAGNOSTICS
2/25/21
Ng JJ, Liang ZC, Choong A | J Intensive Care
Aim: To quantitatively synthesize available literature by using meta-analysis of proportions to estimate the weighted average incidence of PTE in critically ill COVID-19 patients admitted to the intensive care unit (ICU).
RECENTLY UPDATED
2/24/21
Jamebozorgi AH, Agoush L, NooriHekmat S, et al. | Research Square
Aim: To systematically review the challenges and prerequisites, strategies, and measures related to the retention of health workers during the disaster.
2/24/21
Corona G, Pizzocaro A, Vena W, et al. | Rev Endocr Metab Disord
Aim: To provide an overview and a meta-analysis of main predictors and of country differences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-associated mortality rate (MR) in hospitalized patients. 
RECENTLY UPDATED
2/24/21
Ma S, Xu C, Liu S, et al. | Signal Transduct Target Ther
Aim: To address the efficacy and safety of corticosteroids among severe COVID-19 patients.
RECENTLY UPDATED
2/24/21
Widyadharma IPE, Hendellyn A, Dewi A | Egypt J Neurol Psychiatr Neurosurg
Aim: To briefly review neurologic manifestation in COVID-19 infection in the Asia region (South East Asia and the Western Pacific Region).
2/24/21
Martins MM, Prata-Barbosa A, da Cunha AJLA | Paediatr Int Child Health
Aim: To review the evidence on clinical presentations, ways of transmission, severity and prognosis of SARS-CoV-2 infection in children and adolescents.
2/22/21
Conrado PCV, Sakita KM, Arita GS, et al. | Photodiagnosis Photodyn Ther
Aim: To assess whether photodynamic therapy and its mechanisms of action could be effective in inactivating SARS-CoV-2.
2/22/21
Soheili M, Moradi G, Baradaran HR, et al. | J Matern Fetal Neonatal Med
Aim: To find out whether COVID-19 may cause different manifestations and outcomes in the antepartum and postpartum period or not.
2/22/21
Koeppen M, Rosenberger P, Magunia H | Clin Med Insights Circ Respir Pulm Med
Aim: To assess the prevalence of cardiovascular comorbidities and complications in ICU-admitted coronavirus disease 2019 (COVID-19) patients.
2/22/21
Patel RH, Acharya A, Chand HS, et al. | AIDS Res Hum Retroviruses
Aim: To examine trends of clinical outcomes among patients co-infected with HIV and SARS-CoV-2.
2/22/21
Rambo APS, Goncalves LF, Fonzales AI, et al. | Sao Paulo Med J
Aim: To present scientific evidence regarding the impact of COVID-19 spreaders.
2/22/21
Hawkins RB, Mehaffey JH, Charles EJ, et al. | Transplantation
Aim: To review the evidence on lung transplantation for severe post-coronavirus disease 2019 respiratory failure, including patient selection, perioperative management, and expected outcomes.
2/22/21
Hoste L, Van Paemel R, Haerynck F | Eur J Pediatr
Aim: To perform a systematic review of published cases of this novel multisystem inflammatory syndrome in children associated with COVID-19. 
RECENTLY UPDATED
2/22/21
Silva DFO, Cobucci RN, de Paula Soares-Rachetti V, et al. | Cien Saude Colet
Aim: To identify the prevalence of anxiety among health professionals during the COVID-19 pandemic.
2/22/21
Ahmed S, Jafri L, Hoodbhoy Z, et al. | Indian J Crit Care Med
Aim: To review the published literature on the prognostic role of serum procalcitonin (PCT) in COVID-19 cases.
2/22/21
De Sire, A, Andrenelli E, Negrini F, et al. | Eur J Phys Rehabil Med
Aim: To report data of a systematic search performed on papers published in July 2020.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/22/21
Gesesew HA, Koye DN, Fetene DM, et al. | BMJ Open
Aim: To provide a comprehensive evidence on risk factors for transmission, disease severity and COVID-19 related deaths in Africa.
2/22/21
Roshanshad A, Kamalipour A, Ashraf MA, et al. | Iran J Microbiol
Aim: To investigate the latest clinical evidence on the efficacy and safety of treatment with Remdesivir in hospitalized patients with COVID-19.
2/22/21
John A, Okolie C, Eyles E | F1000Res
Aim: To identify and appraise any newly published evidence from around the world that assesses the impact of the COVID-19 pandemic on suicide deaths, suicidal behaviours, self-harm and suicidal thoughts, or that assesses the effectiveness of strategies to reduce the risk of suicide deaths, suicidal behaviours, self-harm and suicidal thoughts, resulting from the COVID-19 pandemic.
RECENTLY UPDATED
2/22/21
Rahimzadeh M, Naderi N | J Med Virol
Aim: To shed light on COVID-19 mediated immune malfunction and highlight possible clues for effective treatments of this disease.
2/19/21
Chee ML, Ong MEH, Siddiqui FJ, et al. | medRxiv
Aim: To systematically review and critically appraise the current evidence on AI applications for COVID-19 in intensive care and emergency settings, focusing on methods, reporting standards, and clinical utility.
DIAGNOSTICS
2/19/21
Zhong Z, Li H, Zhu J, et al. | Medicine
Aim: To summarize the clinical characteristics of patients with severe or critically ill coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/19/21
Irfan O, Muttalib F, Tang K, et al. | Arch Dis Child
Aim: To compare paediatric COVID-19 disease characteristics, management and outcomes according to World Bank country income level and disease severity.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/19/21
Taherifard E, Taherifard E, Movahed H, et al. | Hematology
Aim: To systematically review the hematologic autoimmune complications in these patients.
CLINICAL CHARACTERISTICS
2/19/21
Javed A | CNS Neurol Disord Drug Targets
Aim: To assess the associated neurological manifestations with SARS CoV-2 infection.
CLINICAL CHARACTERISTICS
2/19/21
Creta M, Sagnelli C, Celentano G, et al. | J Med Virol
Aim: To highlight currently available literature data on the involvement of the urinary and male genital systems in SARS-SoV-2 infection.
CLINICAL CHARACTERISTICS
2/19/21
Dotto L, de Azevedo Kinalski M, Machado PS, et al. | J Evid Based Med
Aim: To assess the characteristics of different designs of systematic reviews (SRs) registered in the International Prospective Register of Systematic Reviews (PROSPERO) about COVID-19.
2/19/21
Godini H, Hoseinzadeh E, Hossini H | Rev Environ Health
Aim: To review the evidence on water and wastewater as potential sources of SARS-CoV-2 transmission.
INFECTION CONTROL
2/17/21
Henrina J, Putra ICS, Lawrensia S, et al. | Proj Pediatr Cardiol
Aim: To investigate cardiac manifestations, treatment characteristics, and outcomes of paediatric inflammatory multisystem syndrome (PIMS) temporally associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) (PIMS-TS).
CLINICAL CHARACTERISTICS
2/17/21
Roshdy A, Zaher S, Fayed H, et al. | Front Cardiovasc Med
Aim: To report the cardiac tissue autopsy findings in coronavirus disease 2019 (COVID-19) decedents.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Maslennikov R, Poluektova E, Ivashkin V, et al. | Infect Dis
Aim: To provide a detailed systematic review of diarrhoea in adults with COVID-19.
CLINICAL CHARACTERISTICS
2/17/21
Bonora BM, Avogaro A, Fadini GP | J Endocrinol Invest
Aim: To summarize the current state of the art on DPP4i treatment and COVID-19-related outcomes in patients with diabetes mellitus.
CANDIDATE THERAPEUTICS
2/17/21
Atmosudigdo I, Pranata R, Anthonius M, et al.  | J Clin Exp Hepatol
Aim: To evaluate whether dyslipidemia affects the mortality and severity of COVID-19, we also aimed to evaluate whether other comorbidities influence the association.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Manyati TK, Mutsau M | Health Technol
Aim: To explore the effectiveness of telehealth interventions for the diagnosis, contact tracing and care of the corona virus disease of 2019 in sub Saharan Africa.
INFECTION CONTROL
2/17/21
Sirois F, Owens J | Front Psychiatry
Aim: To examine the factors associated with psychological distress among HCW during an outbreak.
RECENTLY UPDATED
MENTAL HEALTH
2/17/21
Nakhlband A, Fakhari A, Azizi H | Naunyn Schmiedebergs Arch Pharmacol
Aim: To assess outcomes of IFN-beta treatment in COVID-19 patients.
CANDIDATE THERAPEUTICS
2/17/21
Desborough J, Dykgraaf SH, Phillips C, et al. | Fam Pract
Aim: To synthesize accounts of primary care lessons learnt from past epidemics and their relevance to COVID-19.
INFECTION CONTROL
2/17/21
Bansal V, Mahapure KS, Bhurwal A, et al. | Front Med
Aim: To provide a detailed overview of existing literature on Remdesivir in COVID-19 to evaluate the benefits and adverse events. 
CANDIDATE THERAPEUTICS
2/17/21
Gao Y, Chen Y, Liu M, et al. | Epidemiol Infect
Aim: To clarify the association between nervous system diseases and severity or mortality in patients with COVID-19.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Mohamed MFH, A-Shokri S, Yousaf Z, et al. | Front Cardiovasc Med
Aim: To systematically review the literature and explore the pooled prevalence of VTE, PE, and DVT in critically ill COVID-19 patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Winograd DM, Fresquez CL, Egli M, et al. | Patient Educ Couns
Aim: To review the evidence on the risk communication interventions to mitigate risk from viruses to determine if such interventions are efficacious.
INFECTION CONTROL
2/17/21
Kumar D, Severn M | CADTH
2/17/21
Kheyami ZA, Alharthi SS, Alanazi NS, et al. | Ann Med Health Sci Res
Aim: To determine the safety of systemic steroids and mortality rate in severe COVID-19 patients.
CANDIDATE THERAPEUTICS
2/17/21
Chaudhary R, Garg J, Houghton DE, et al. | Mayo Clin Proc Innov Qual Outcomes
Aim: To evaluate differences in thrombo-inflammatory biomarkers between patients with severe COVID-19 infection/death and mild infection.
CLINICAL CHARACTERISTICS
2/17/21
Jenner WJ, Kanji R, Mirsadraee S, et al. | J Thromb Thrombolysis
Aim: To identify the rate of thrombotic complications in ICU-treated patients with COVID-19, to inform recommendations for diagnosis and management.
CLINICAL CHARACTERISTICS
2/16/21
Umakanthan S, Chattu VK, Ranade AV, et al. | AIMS Public Health
Aim: To give a detailed insight into the recent trends of diagnosis and therapeutic options for COVID-19. 
CANDIDATE THERAPEUTICS
2/16/21
Labad J, Gonzalez-Rodriguez A, Cobo J, et al.  | PeerJ
Aim: To explore whether the coronavirus disease 2019 (COVID-19) pandemic is associated with toilet paper hoarding and to assess which risk factors are associated with the risk of toilet paper hoarding.
RECENTLY UPDATED
2/16/21
Sharifian-Dorche M, Sahraian MA, Fadda G, et al. | Mult Scler Relat Disord
Aim: To review the existing literature investigating the impact of disease-modifying therapies(DMT) on COVID-19 risks in this group of patients.
CANDIDATE THERAPEUTICS
2/16/21
Chang R, Elhusseiny KM, Yeh Y, et al. | PLoS One
Aim: To review the evidence on COVID-19 intensive care unit (ICU) patient characteristics, rates and risks of invasive mechanical ventilation (IMV) and associated outcomes.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/16/21
Ding H, He F, Lu YG, et al. | Eur Rev Med Pharmacol Sci
Aim: To evaluate the effects of non-drug interventions on anxiety, depression and sleep in patients with COVID-19 to provide guidance for clinical application.
MENTAL HEALTH
2/16/21
Wang J, Zhong Z, Mo Y, et al. | Eur Rev Med Pharmacol Sci
Aim: To determine the incidence of the clinical manifestations of COVID-19 in children.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
2/16/21
Fiest KM, Leigh JP, Krewulak KD, et al. | BMC Psychiatry
Aim: To review the evidence on the experiences and management of psychological symptoms in physicians during infectious disease outbreaks to better understand and support physician health during this unprecedented time.
MENTAL HEALTH
2/16/21
Ebina-Shibuya R, Namoong H, Horita N, et al. | J Thorac Dis
Aim: To evaluate HCQ/CQ treatment for COVID-19.
CANDIDATE THERAPEUTICS
2/16/21
Cavalcante-Leao BL, de Araujo C, Basso I, et al. | J Clin Exp Dent
Aim: To verify whether there is evidence in the literature regarding the decrease in viral load present in saliva after using three types of mouthwashes.
RECENTLY UPDATED
INFECTION CONTROL
2/16/21
Sarria-Guzman Y, Fusaro C, Bernal JE, et al. | J Infect Dev Ctries
Aim: To identify and to evaluate the reports associated on Knowledge, Attitude and Practices (KAP) towards COVID-19 pandemic in America.
2/16/21
Zhu F, Zozaya C, Zhou Q, et al. | Arch Dis Child Fetal Neonatal Ed
Aim: To systematically review and meta-analyse the available evidence for the presence of SARS-CoV-2 genome in the breastmilk of mothers who tested positive for COVID-19.
INFECTION CONTROL
2/16/21
Zinellu A, Mangoini AA | Front Med
Aim: To review the available evidence on the clinical implications of this protein specifically in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/16/21
Khan FA, Stewart I, Fabbri L, et al. | Thorax
Aim: To systematically review and assess the effectiveness of specific interleukin-1 and -6 inhibitors for the treatment of coronavirus-related infections. 
RECENTLY UPDATED
CANDIDATE THERAPEUTICS
2/16/21
Darbandi A, Asadi A, Ghanavati R, et al. | Int J Infect Dis
Aim: To evaluate the effects of probiotic on patient’s respiratory tract infection (RTI), a systematic review was conducted on randomized controlled trials (RCTs). 
CANDIDATE THERAPEUTICS
2/16/21
Bignardi PR, Vengrus CS, Aquino BM, et al. | Pathog Glob Health
Aim: To assess the association of hydroxychloroquine use with the virological cure, clinical recovery, mortality, and development of adverse effects in patients with COVID-19. 
CANDIDATE THERAPEUTICS
2/16/21
Sarfraz A, Sarfraz Z, Razzack AA, et al. | Clin Appl Thromb Hermost
Aim: To determine the risk of developing VTE after corticosteroid administration during COVID-19 treatment.
CANDIDATE THERAPEUTICS
2/15/21
Yazew BG, Abate HK, Mekonnen CK | Patient Prefer Adherence
Aim: To investigate the status of people’s knowledge, attitude, and practice about coronavirus disease preventive measures in Ethiopia in 2020.
2/12/21
Singh B, Ryan H, Kredo T, et al. | Cochrane Database Syst Rev
Aim: To evaluate the effects of chloroquine or hydroxychloroquine for treatment people with COVID-19 and for preventing infection in people at risk of exposure or exposed to SARS-CoV-2.
UPDATED
CANDIDATE THERAPEUTICS
2/12/21
Ng WH, Tipih T, Makoah NA, et al. | mBio
Aim: To evaluate the correlation between comorbidities and their role in the exacerbation of disease in COVID-19 patients leading to fatal outcomes. 
CLINICAL CHARACTERISTICS
2/12/21
Nanda A, Hung I, Kwong A, et al. | J Evid Based Med
Aim: To evaluate the preclinical and clinical evidence on use of cloth and surgical face masks in SARS-CoV-2 transmission and proposes a trial to gather further evidence.
INFECTION CONTROL
2/11/21
Nasiri K, Dimitrova A | J Dent Sci
Aim: To evaluate saliva specimen in comparison to nasopharyngeal swab (NPS) specimen.
DIAGNOSTICS
2/11/21
Tur-Kaspa I, Tur-Kaspa T, Hildebrand G, et al. | F S Rev
Aim: To determine if COVID-19 is an STD or not, and to clarify its possible effect on fertility.
CLINICAL CHARACTERISTICS
2/11/21
Yan W, Chen D, Bigambo FM, et al. | BMC Infect Dis
Aim: To determine differences in blood cells, lymphocyte subsets, and cytokines in COVID-19 patients with different clinical stages.
CLINICAL CHARACTERISTICS
2/11/21
Vergara-Merino L, Meza N, Couve-Perez C, et al. | Acta Obstet Gynecol Scand
Aim: To conduct a comprehensive analysis of the current evidence on prognosis of COVID-19 in pregnant women.
CLINICAL CHARACTERISTICS
2/11/21
Bauer M, Groesdonk HV, Preissing F, et al. | Anaesthesist
Aim: To estimate 30-day and 90-day mortality of patients with sepsis and patients with septic shock in Germany and to compare the mortality with that of other industrialized regions (Europe, North America).
2/11/21
Jin Y, Trope GE, El-Defrawy S, et al. | Eur J Ophthalmol
Aim: To summarize COVID-19 research endeavors by ophthalmologists/researchers in terms of publication numbers, journals and author countries, and to detail key findings.
CLINICAL CHARACTERISTICS
2/11/21
Bavishi C, Whelton PK, Mancia G, et al. | J Hypertens
Aim: To evaluate the association of angiotensin-converting-enzyme inhibitors (ACEI) or AT1 blockers (ARB) therapy with clinical outcomes in patients with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/11/21
Thompson H, Mousa A, Dighe A, et al.  | Clin Infect Dis
Aim: To estimate secondary attack rates (SAR) and observed reproduction numbers (Robs) in different settings exploring differences by age, symptom status, and duration of exposure.
UPDATED
INFECTION CONTROL
2/11/21
Alonso SG, Marques G, Barrachina I, et al. | Health Technol
Aim: To present a systematic review of the application of telemedicine and e-health systems to combat COVID-19. 
INFECTION CONTROL
2/10/21
Hariyanto TI, Rizki NA, Kurniawan A | Int Arch Otorhinolaryngol
Aim: To analyze the potential usefulness of anosmia or hyposmia in the detection of the COVID-19 infection.
DIAGNOSTICS
2/10/21
Syangtan G, Bista S, Dawadi P, et al. | Front Public Health
Aim: To review the evidence on the frequency of asymptomatic individuals and estimated occurrence by age group and gender.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Jayant K, Reccia I, Virdis F, et al. | Clin Transplant
Aim: To determine the pooled prevalence of outcomes among hospitalized LTx recipients with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Dhar SK, Vishnupriayn K, Damodar S, et al. | Heliyon
Aim: To establish association between induced cytokines and COVID-19 disease severity to help in prognosis and clinical care.
CLINICAL CHARACTERISTICS
2/10/21
 | NSW Health COVID-19 Critical Intelligence Unit
2/10/21
Marafini I, Troncone E, Rocchetti I, et al. | Front Pharmacol
Aim: To determine the risk of RTIs with vedolizumab in patients with IBD.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Kumar J, Meena J, Yadav A, et al.  | J Matern Fetal Neonatal Med
Aim: To synthesize the current evidence for the presence of SARS-CoV-2 RNA in the human milk of mothers with confirmed COVID-19 and its potential role in neonatal SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Umnuaypornlert A, Kanchanasurakit S, Lucero-Prisno DE, et al. | Tob Induc Dis
Aim: To determine the association between smoking and disease severity in COVID-19 infected patients.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Dorantes-Acosta E, Ávila-Montiel D, Klünder-Klünder M, et al. | Front Oncol
Aim: To understand the survival and associated complications in pediatric cancer patients as well as their hospitalization, intensive care, and ventilation care (supplemental oxygen/endotracheal intubation) needs.
CLINICAL CHARACTERISTICS
2/10/21
Nassar M, Nso N, Baraka B, et al. | Diabetes Metab Syndr
Aim: To summarize the prevalence, clinical findings, and outcomes of COVID-19 in patients with T1DM, based on the findings of available evidence.
2/9/21
Chedid M, Waked R, Haddad E, et al. | J Infect Public Health
Aim: To report available information in the literature regarding frequency, indications, types of antibiotic usage, duration, and their efficacy in Covid-19 patients.
2/8/21
Sunjaya AP, Allida SM, Di Tanna GL, et al. | J Asthma
Aim: To summarise evidence on the risk of infection, severe illness and death from COVID-19 in people with asthma.
2/8/21
Laurentius A, Mendel B, Prakoso R | Egypt Heart J
Aim: To show clinical outcome of renin-angiotensin-aldosterone system blockers in hospital treatment of hypertensive patients with coronavirus disease 2019
CLINICAL CHARACTERISTICS
2/8/21
Bhatta M, Nandi S, Dutta S, et al. | Hum Vaccin Immunother
Aim: To analyze the availability, development and status of new COVID-19 vaccine candidates as well as the status of vaccines for other diseases that might be effective against SARS-CoV-2 infection.
CANDIDATE THERAPEUTICS
2/8/21
Li P, Li L, Wang S, et al. | Cancer Med
Aim: To systematically review the present evidence on the relationship between antitumor therapy and the clinical outcomes of COVID?19 and to analyze and summarize the available studies in this meta?analysis.
CLINICAL CHARACTERISTICS
2/8/21
Vegivinti CTR, Pederson JM, Saravu K, et al. | J Clin Apher
Aim: To examine clinical outcomes associated with convalescent plasma therapy in COVID-19 patients.
CANDIDATE THERAPEUTICS
2/8/21
Dabone C, Mbagwu I, Muray M, et al. | J Racial Ethn Health Disparities
Aim: To assess the food insecurity conditions of ACB populations globally during the COVID-19 pandemic.
2/8/21
Servante J, Swallow G, Thornton JG, et al. | BMC Pregnancy Childbirth
Aim: To determine the rate of arterial or venous thrombosis in pregnant women with confirmed or suspected COVID-19 and to estimate the rate of acquired coagulopathy in pregnant women with confirmed or suspected COVID-19.
CLINICAL CHARACTERISTICS
2/8/21
Mir T, Sattar Y, Ahmad J, et al. | Catheter Cardiovasc Interv
Aim: To meta?analyze studies that examined in?hospital cardiac arrest in COVID patients.
CLINICAL CHARACTERISTICS
2/8/21
Kim DH, Kim SW, Stybayeva G, et al. | Clin Exp Otorhinolaryngol
Aim: To evaluate the diagnostic value of the various symptoms of COVID-19 in the screening of this disease.
DIAGNOSTICS
2/8/21
Yuan K, Gong Y, Liu L, et al. | Mol Psychiatry
Aim: To provide a reliable estimate of the worldwide prevalence of PTSD after large-scale pandemics as well as associated risk factors.
MENTAL HEALTH
2/8/21
 | NSW Health COVID-19 Critical Intelligence Unit
2/8/21
Pal R, Banerjee M, Yadav U, et al. | Postgrad Med J
Aim: To provide an updated summary and collate the effect of statin use on clinical outcomes in COVID-19 using unadjusted and adjusted risk estimates.
CANDIDATE THERAPEUTICS
2/5/21
Beyrouti R, Best JG, Chandratheva A, et al. | J Neurol
Aim: To describe the characteristics of spontaneous symptomatic intracerebral haemorrhage (ICH) associated with COVID-19.
CLINICAL CHARACTERISTICS
2/5/21
Xu Z, Tang Y, Huang Q, et al. | BMC Nephrol
Aim: To evaluate the incidence of AKI in hospitalized COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/4/21
Belsky JA, Tullius BP, Lamb MG, et al. | J Infect
Aim: To define clinical features, laboratory testing, therapeutic interventions and outcomes in immunocompromised patients and then compared these results to the general population with COVID-19.
2/4/21
Anderson G, Casasanta D, Cocchieri A, et al. | J Clin Nurs
Aim: To identify the main diagnostic features of SARS-CoV-2 positive patients at the time of hospitalization and their prevalence.
DIAGNOSTICS
2/4/21
Aghalari Z, Dahms H, Sosa-Hernandez JE, et al. | Environ Res
Aim: To evaluate SARS-COV-2 transmission through indoor air in hospitals and its prevention methods.
2/4/21
Jain V, Kanchan T, Krishan K | Acta Biomed
Aim: To review the evidence on the vertical transmission of SARS-CoV-2.
INFECTION CONTROL
2/4/21
Elshazli RM, Kline A, Elgaml A, et al. | J Med Virol
Aim: To identify COVID-19 patients presenting with gastrointestinal (GI) symptoms during the first and second pandemic waves and investigate their association with the disease outcomes.
CLINICAL CHARACTERISTICS
2/4/21
Li G, Yang Y, Gao D, et al. | Int J Med Sci
Aim: To comprehensively explore the prevalence of transaminase elevation and liver injury in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/4/21
Alamer AA, Almulhim AS, Alrashed AA, et al. | Healthcare
Aim: To estimate the pooled risks of mortality and disease severity associated with ACEI/ARB use during the first wave of the pandemic.
CLINICAL CHARACTERISTICS
2/4/21
Rezagholizadeh A, Khiali S, Sarbakhsh P, et al. | Eur J Pharmcol
Aim: To evaluate the efficacy and safety of remdesivir administration in COVID-19 patients. 
2/3/21
Naeini MB, Sahebi M, Nikbakht F, et al. | Obes Med
Aim: To quantify meta-analytic findings on the association of cardiovascular disease (CVD) comorbidities and COVID-19 severity.
CLINICAL CHARACTERISTICS
2/3/21
Hatmi ZN | SN Compr Clin Med
Aim: To conduct a systematic review of published systematic reviews to provide comprehensive updated information on COVID-19.
CLINICAL CHARACTERISTICS
2/3/21
He X, Cheng X, Feng X, et al. | Front Public Health
Aim: To review the clinical symptoms of the COVID-19 epidemic systematically.
CLINICAL CHARACTERISTICS
2/3/21
Hasnain M, Pasha MF, Ghani I | J Biosaf Biosecur
Aim: To review the evidence on the combined measures taken to control the transmission of COVID-19 in Wuhan.
INFECTION CONTROL
2/3/21
Li J, Liao X, Zhou Y, et al. | Shock
Aim: To review the evidence on the response to glucocorticioids treatment in COVID-19 and SARS patients.
UPDATED
CANDIDATE THERAPEUTICS
2/3/21
Castaneda CA, Castillo M, Rojas JL, et al. | Rev Peru Med Exp Salud Publica
Aim: To describe the risk of infection and developing severe COVID-19 in cancer patients.
UPDATED
2/3/21
Lopez-Valenciano A, Suarez-Iglesias D, Sanchez-Lastra MA, et al. | Front Psychol
Aim: To analyze the impact that the COVID-19 lockdown had on the amount of physical activity performed by university students.
2/3/21
Scooppettuolo P, Borrelli S, Naeije G | Brain Behav Immun Health
Aim: To provide a clinical approach of SARS-CoV-2 neurological complications based on the direct or indirect (systemic/immune-mediated) role of the SARS-CoV-2 in their genesis.
CLINICAL CHARACTERISTICS
2/3/21
Nasiri N, Sharifi H, Bazrafshan A, et al. | J Ophthalmic Vis Res
Aim: To investigate the prevalence of ocular manifestations in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/3/21
Pourmalek F, Hemami MR, Janani L, et al. | BMC Public Health
Aim: To inform the researchers about the methodology and results of epidemic estimation studies performed for COVID-19 epidemic in Iran, we aimed to perform a rapid review.
UPDATED
2/3/21
Cevik M, Tate M, Lloyd O, et al. | Lancet Microbe
Aim: To characterise the viral load dynamics of SARS-CoV-2, duration of viral RNA shedding by RT-PCR, and viable virus shedding in various body fluids, and to compare SARS-CoV-2 viral dynamics with those of SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV).
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Xiang G, Li X, Chen Z, et al. | Ann Palliat Med
Aim: To systematically review the clinical risk factors for fatal outcome of COVID-19.
UPDATED
2/1/21
Li H, Zhao Y, Zhou L, et al. | Dermatol Ther
Aim: To present heterogeneous cutaneous, histopathological manifestations in COVID?19 patients, to investigate the possible relationship between cutaneous manifestations and histopathological features in COVID?19 infection.
CLINICAL CHARACTERISTICS
2/1/21
Pijls BG, Jolani S, Atherley A, et al. | BMJ Open
Aim: To describe the associations of age and sex with the risk of COVID-19 in different severity stages ranging from infection to death.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Ghimire S, Sharma S, Patel A, et al. | SN Compr Clin Med
Aim: To provide a more comprehensive and generalizable understanding of the GI manifestations, and its association with severity in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/1/21
Yisak H, Ewunetei A, Kefale B, et al. | Risk Manag Healthc Policy
Aim: To summarize and decide if there were a link between vitamin D status and COVID-19 infection and prognosis.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Sood M, Sharma S, Sood I, et al. | SN Compr Clin Med
Aim: To analyse the clinical features, proposed pathogenesis and current treatment options for effective management of children with this novel entity.
CLINICAL CHARACTERISTICS
2/1/21
Diaz LA, Idalsoaga F, Cannistra M, et al. | World J Gastroenterol
Aim: To characterize hepatic pathological findings in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Wibowo A, Pranata R, Astuti A, et al. | J Intensive Care
Aim: To assess whether ventricular longitudinal strain can be used as a prognostication tool in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Lee RA, Herigon JC, Benedetti A, et al. | J Clin Microbiol
Aim: To understand the performance of alternative sample types compared to NP swabs
UPDATED
DIAGNOSTICS
2/1/21
Yoon SH, Yang S, Cho H, et al.  | Eur Rev Med Pharmacol Sci
Aim: To evaluate the diagnostic accuracy of the Food and Drug Administration Emergency Use Authorization (FDA-EUA) authorized point-of-care tests (POCTs) for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
UPDATED
DIAGNOSTICS
2/1/21
d'Ettore G, Ceccarelli G, Santinelli L, et al. | Int J Environ Res Public Health
Aim: To analyze the literature to discover which topics have been focused on and what the latest developments are in managing the occupational risk of PTSS in HCWs during the current pandemic.
MENTAL HEALTH
2/1/21
Santabarbara J, Bueno-Notivol J, Lipinicki DM, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To review the evidence on the prevalence of anxiety in health care professionals during the COVID-19 pandemic.
MENTAL HEALTH
2/1/21
Yang J, Zheng Y, Gou X, et al. | Int J Infect Dis
Aim: To assess the prevalence of comorbidities in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients and the risk of underlying diseases in severe patients compared to non-severe patients.
CLINICAL CHARACTERISTICS
2/1/21
Merola E, Armelao F, de Pretis G | Acta Gastroenterol Belg
Aim: To assess the frequency of gastrointestinal (GI) involvement in COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Martha JW, Wibowo A, Pranata R | Postgrad Med J
Aim: To evaluate the prognostic performance of elevated lactate dehydrogenase (LDH) in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Gronholm P, Nose M, van Brakel WH, et al. | Epidemiol Psychiatr Sci
Aim: To develop recommendations for strategies and interventions to reduce stigma and discrimination related to COVID-19.
UPDATED
MENTAL HEALTH
2/1/21
Agostini F, Mangone M, Ruiu P, et al. | J Rehabil Med
Aim: To identify the best evidence to define rehabilitative approaches to acute and post-acute phases of coronavirus 2019 (COVID-19) disease.
CANDIDATE THERAPEUTICS
2/1/21
Al-abdouh A, Bizanti A, Barbarawi M, et al. | Contemp Clin Trials
Aim: To evaluate the effect of remdesivir in the treatment of moderate and severe COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
2/1/21
Lee HW, Yoon C, Jang EJ, et al. | Thorax
Aim: To investigate if ACEI/ARB use is associated with the risk of mortality and severe disease in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Zhang T, Huang W, Guan W, et al. | J Thorac Dis
Aim: To review the evidence on the clinical characteristics between severe and non-severe pateints in the outbreak of COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Uaprasert N, Moonla C, Sosothikul D, et al. | Clin Appl Thromb Hermost
Aim: To estimate the burden of systemic coagulation activation in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Chen C, Zhu C, Yan D, et al. | Int J Infect Dis
Aim: To summarize the epidemiological and radiographical characteristics of asymptomatic infections with COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Prati G, Mancini AD | Psychol Med
Aim: To determine the psychological impact of COVID-19 lockdowns on the general population.
MENTAL HEALTH
2/1/21
Bastos ML, Perlman-Arrow S, Menzies D, et al. | Ann Intern Med
Aim: To determine the difference in sensitivity for SARS-CoV-2 detection between nasopharyngeal swabs and saliva and estimate the incremental cost per additional SARS-CoV-2 infection detected with nasopharyngeal swabs.
UPDATED
DIAGNOSTICS
2/1/21
Han YJ, Lee KW, Yoon S, et al. | Theranostics
Aim: To highlight therapeutic agents that might be effective in treating COVID-19.
CANDIDATE THERAPEUTICS
1/29/21
Khatami F, Saatchi M, Zadeh SST, et al. | Sci Rep
Aim: To determine the diagnostic value of an initial chest CT scan in patients with COVID-19 infection in comparison with RT-PCR. 
DIAGNOSTICS
1/29/21
Yu YJ, Park YS, Keller A, et al. | Int J Environ Res Public Health
Aim: To synthesize existing findings (both qualitative and quantitative) that focus on the social and cultural impacts of coronaviruses in order to gain a better understanding of the COVID-19 pandemic.
1/29/21
Lawes-Wickwar S, Ghio D, Tang MY, et al. | Vaccines
Aim: To identify and synthesise evidence relating to effective messaging for encouraging vaccination in order to prevent virus transmission during pandemics or epidemics.
UPDATED
INFECTION CONTROL
1/29/21
Peravali M, Joshi I, Ahn J, et al. | JTO Clin Res Rep
Aim: To outline patient characteristics, challenges in diagnosis and treatment, and outcomes of lung cancer patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Goel H, Gupta I, Mourya M, et al. | Obstet Gynecol Sci
Aim: To review the evidence on the clinical and laboratory parameters of COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Kinobe RT, Owens L | Fundam Clin Pharmacol
Aim: To present an integrative, critical appraisal of the qualitative and quantitative antiviral properties of ivermectin for putative applications in agriculture and medicine with examination of SARS?CoV?2.
CANDIDATE THERAPEUTICS
1/29/21
Tleyjeh IM, Bin Abdulhak AA, Tlayjeh H, et al. | Am J Ther
Aim: To perform a meta-analysis of the association between prior use of ACEIs and ARBs and the risk of SARS-CoV-2 infection or hospitalization due to COVID-19 disease.
CLINICAL CHARACTERISTICS
1/29/21
Langford BJ, So M, Raybardhan S, et al. | Clin Microbiol Infect
Aim: To estimate the prevalence and associated factors of antibiotic prescribing in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Arias FA, Chavez PT, Panato AM, et al. | J of Pharmaceutical Res
Aim: To conduct a systematic review of the possible antivirals studied that could be useful in this public health catastrophe.
CANDIDATE THERAPEUTICS
1/29/21
Lee JJ, Montazerin SM, Jamil A, et al. | J Med Virol
Aim: To review and synthesize the current evidence on the association of RDW levels with COVID?19 mortality and severity.
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Mendes NF, Jara CP, Mansour E, et al. | Allergy Asthma Clin Immunol
Aim: To conduct a systematic review of the diagnosis of asthma as a premorbid condition in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Silverio A, Di Maio M, Citro R, et al. | BMC Cardiovasc Disord
Aim: To investigate the relationship between cardiovascular risk factors and in-hospital mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Baldini T, Asioli GM, Romoli M, et al. | Eur J Neurol
Aim: To systematically review the available evidence in the literature for cerebral venous thrombosis (CVT) in association with coronavirus disease-2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Chen M, Qin R, Mei J, et al. | Int J Infect Dis
Aim: To investigate the diagnostic effectiveness of SARS-CoV-2 specific antibodies stratified by different positive results.
DIAGNOSTICS
1/29/21
Jafari M, Pormohammad A, Sheikh Neshin SA, et al. | Rev Med Virol
Aim: To provide comprehensive data regarding pregnant patients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
1/29/21
Huang C, Soleimani J, Herasevich S, et al. | Mayo Clin Proc
Aim: To synthesize the current and emerging literature describing the clinical features, treatment, outcomes, and risk factors associated with poor prognosis among critically ill patients with COVID-19 during the early months of the pandemic. To provide frontline clinicians with insights for the effective management of severely ill patients with COVID-19. To identify knowledge gaps to guide future research endeavors.
CLINICAL CHARACTERISTICS
1/29/21
Singh AK, Jena A, Kumar-M P, et al. | Intest Res
Aim: To review the evidence on the various clinical manifestations of SARS-CoV-2 in patients with IBD, and to estimate the pooled prevalence of different clinical manifestations.
CLINICAL CHARACTERISTICS
1/29/21
Barycka K, Szarpak L, Filipiak KJ, et al. | PLoS One
Aim: To review the relevant and available published RCTs with the aid of the increased power of meta-analytic methods in order to assess the effectiveness of medical masks and N95 respirators in reducing the risk of respiratory infections.
INFECTION CONTROL
1/29/21
Butler-Laporte G, Lawandi A, Schiller I, et al. | JAMA Intern Med
Aim: To assess the diagnostic accuracy of saliva NAAT for COVID-19.
DIAGNOSTICS
1/29/21
Gross JV, Mohren J, Erren TC | BMJ Open
Aim: To review the evidence on health risks at the workplace and the effectiveness of enacted preventative measures for COVID-19.
INFECTION CONTROL
1/29/21
Gholami M, Fawad I, Shadan S, et al. | Int J Infect Dis
Aim: To describe the clinical outcomes and risk factors for SARS- CoV-2 infection in HCW.
CLINICAL CHARACTERISTICS
1/29/21
Xiang Y, Jia Y, Chen L, et al. | Infect Dis Model
Aim: To review the evidence on epidemic prediction models of COVID-19 and the public health intervention strategies.
INFECTION CONTROL
1/29/21
Raynaud M, Zhang H, Louis K, et al. | BMC Med Res Methodol
Aim: To review and categorize COVID-19-related medical research and to critically appraise peer-reviewed original articles.
1/29/21
Yasuhara J, Watanabe K, Takagi H, et al. | Pediatr Pulmonol
Aim: To investigate the epidemiology and clinical course of MIS-C.
CLINICAL CHARACTERISTICS
1/29/21
Rodriguez-Guerra M, Jadhav P, Vittorio TJ | Drugs Context
Aim: To assess the efficacy and safety of these available therapies in light of current evidence. 
1/29/21
Anglemyer A, Moore TH, Parker L, et al. | Cochrane Database Syst Rev
Aim: To assess the benefits, harms, and acceptability of personal digital contact tracing solutions for identifying contacts of an identified positive case of an infectious disease.
UPDATED
INFECTION CONTROL
1/29/21
Vargo D, Zhu L, Benwell B, et al. | Human Behaviour and Emerging Technologies
Aim: To synthesize the rapidly growing literature on digital technology use during the current COVID?19 pandemic. To address the following four topics: (1) the specific digital technologies that have been used, (2) the specific populations who have used these digital technologies, (3) the specific activities that individuals and groups have used these digital technologies, and (4) the specific effects of using these digital technologies on humans during the pandemic.
1/29/21
Parsons JE, Newby KV, French DP | Br J Health Psychol
Aim: To examine interventions reported in the literature to see whether those that include risk messages have been successful in influencing risk appraisals and the subsequent intentions and uptake of vaccination.
INFECTION CONTROL
1/29/21
Parkinson N, Rodgers N, Head Fourman M, et al. | Sci Rep
Aim: To systematically identify and combine existing data from human betacoronavirus research to generate a comprehensive ranked list of host genes involved in COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Xue Y, Sun S, Cai J, et al. | J Renin Angiotensin Aldosterone Syst
Aim: To conduct a meta-analysis on the effects of ACEI/ARB on disease symptoms and laboratory tests in hypertensive patients infected with COVID-19 virus and those who did not use ACEI/ARB.
CLINICAL CHARACTERISTICS
1/29/21
Cao C, Wang J, Li Y, et al. | Int J Clin Pract
Aim: To evaluate the relationship between OM-85 consumption and recurrent respiratory tract infections.
CANDIDATE THERAPEUTICS
1/29/21
Horn M, Ratansi A, Varia M | Region of Peel - Public Health
Aim: To answer the question: what population-level interventions will result in health behaviour change among travellers?
INFECTION CONTROL
1/29/21
Lim MA, Mulyadi Ridia KG, Pranata R | J Clin Orthop Trauma
Aim: To evaluate the 30-day mortality, number and site of fracture, mechanism of injury, and location where injury was sustained during the pandemic compared to pre-pandemic.
1/29/21
Yao MQ, Zheng QX, Xu J, et al. | Journal of Zhejiang University-SCIENCE B
Aim: To summarize data on demographic characteristics, clinical features, and laboratory findings in non-recurrence and recurrence groups as well as to explore critical factors associated with COVID-19 recurrence.
CLINICAL CHARACTERISTICS
1/29/21
Wang Y, Kala MP, Jafar TH | PLoS One
Aim: To evaluate factors associated with psychological distress among the predominantly general population during the COVID-19 pandemic.
MENTAL HEALTH
1/29/21
Zhang Y, Yao F, Kuang X, et al. | Cancer Manag Res
Aim: To evaluate the quality of systematic reviews/meta-analyses (SR/MAs) on alternative exercise traditions in cancer care.
MENTAL HEALTH
1/29/21
Barek MA, Aziz MA, Islam MS | Heliyon
Aim: To evaluate the impact of age, sex, comorbidities, and clinical characteristics on the severity of COVID-19 to help diagnose and evaluate the current outbreak in clinical decision-making.
CLINICAL CHARACTERISTICS
1/29/21
Kitano T, Kitano M, Krueger C, et al. | PLoS One
Aim: To better understand the global epidemiology of COVID-19 in children and differences in outcome across countries.
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Lassi Z, Naseem R, Salam RA, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the impact of the COVID-19 pandemic on immunization campaigns and programs.
UPDATED
INFECTION CONTROL
1/28/21
Yang J, Ma Z, Lei Y | Epidemiol Infect
Aim: To re-evaluate the relationship between obesity and coronavirus-2019 (COVID-19).
CLINICAL CHARACTERISTICS
1/28/21
Mair MDD, Hussain M, Siddiqui S, et al | Br J Radiol
Aim: To perform a systematic review and meta-analysis to compare the diagnostic accuracy of Computed tomography (CT) and initial Reverse transcriptase polymerase chain reaction (RT-PCR) for detecting COVID-19 infection.
DIAGNOSTICS
1/28/21
Sadaf A, Richards JL, Glanz J, et al | Vaccine
Aim: To amass and evaluate the literature on interventions to decrease parental vaccine refusal and hesitancy toward recommended childhood and adolescent vaccines.
INFECTION CONTROL
1/28/21
Piri SM, Edalatfar M, Shool S, et al. | Infect Dis
Aim: To evaluate rate of SARS-CoV-2 recurrence, changes in disease severity, the interval between negative RT-PCR test for SARS-CoV-2 and disease recurrence, disease and patients’ characteristics, risk factors for predicting recurrence and outcomes, as well as the prognosis of recurrent patients.
CLINICAL CHARACTERISTICS
1/28/21
Bhattacharjee S, Banerjee M, Pal R | Postgraduate Medical J
Aim: To summarise the available literature and provide a pooled analysis of the effect of A/AB (without anti-A antibodies) on clinical outcomes in COVID-19 patients compared with B/O (with anti-A antibodies) blood groups.
CLINICAL CHARACTERISTICS
1/28/21
Tabatabaeizadeh SA | Eur J Med Res
Aim: To investigate the airborne transmission of COVID-19 and the role of face mask to prevent it.
INFECTION CONTROL
1/28/21
Paliogiannis P, Mangoni AA, Cangemi M, et al. | Clin Exp Med
Aim: To investigate the associations between serum albumin concentrations and COVID-19 disease severity and adverse outcomes.
CLINICAL CHARACTERISTICS
1/27/21
Hussein MH, Elshazli RM, Attia AS, et al. | J Asthma
Aim: To compare asthmatic and non-asthmatic patients to determine the clinical significance of pre-existing asthma in COVID-19 patients. 
CLINICAL CHARACTERISTICS
1/27/21
Sharifi M, Asadi-Pooya AA, Mousavi-Roknabadi RS | Arch Acad Emerg Med
Aim: To systematically review the epidemiology of burnout and the strategies and recommendations to prevent or reduce it among healthcare providers (HCPs) of COVID-19 wards.
MENTAL HEALTH
1/27/21
Xie J, Wang Q, Xu Y, et al. | Ann Palliat Med
Aim: To summarize the characteristics of COVID-19 patients in the early stage of the pandemic and explore the risk factors of disease progression.
1/27/21
Hoogenes B, Queree M, Townson A, et al.  | J Neurotrauma
Aim: To provide an overview of the clinical presentation, course, and outcomes of COVID-19 in persons with SCI and identify risk factors for severe disease- and COVID-19-related mortality.
UPDATED
CLINICAL CHARACTERISTICS
1/27/21
Hariyanto TI, Putri C, Frinka P, et al. | AIDS Res Hum Retroviruses
Aim: To analyze the relationship between HIV and poor outcomes of COVID-19 infection.
CLINICAL CHARACTERISTICS
1/27/21
Illahi U, Mir MS | Environ Dev Sustain
Aim: To identify and enhance the understanding of the logistical characteristics that play a vital role during pandemics. 
1/27/21
Rahman M, Ahmed R, Moitra M, et al. | Front Psychiatry
Aim: To collate evidence on human rights abuses and violations and resultant mental and behavioral health outcomes of different populations, especially those known to be at high risk or have greater vulnerabilities warranting additional mitigation, prevention, and treatment approaches during COVID-19.
MENTAL HEALTH
1/27/21
Vegivinti CTR, Pederson JM, Saravu K, et al. | Ann Med Surg
Aim: To perform a systematic review and meta-analysis of randomized controlled trials that examined remdesivir treatment for COVID-19.
CANDIDATE THERAPEUTICS
1/27/21
Tian C, Lovrics O, Vaisman A, et al. | Infect Control Hosp Epidemiol
Aim: To investigate risk factors for HCW infection in viral respiratory pandemics (SARS-CoV-2, MERS, SARS CoV-1, influenza A H1N1, influenza H5N1) and improve understanding of HCW risk management amidst the COVID-19 pandemic.
UPDATED
INFECTION CONTROL
1/26/21
Kumar S, Sarma P, Kaur H, et al. | Tissue Cell
Aim: To review the evidence on the utility of different cell culture systems as potential in-vitro models for repurposing and drugs development, vaccine development, isolation and pathogenesis of SARS-COV-2.
CANDIDATE THERAPEUTICS
1/26/21
Hartmann J, Ergang A, Mason D, et al. | Diagnostics
Aim: To review the evidence on thromboelastography for management of patients with COVID-19.
CLINICAL CHARACTERISTICS
1/25/21
Robertson-More C, Wu T | Surg Endosc
Aim: To better outline what is known regarding the risk of viral transmission in surgical smoke.
INFECTION CONTROL
1/25/21
Chtioui MJ, Harzallah N, Jebali MCO, et al. | Tunis Med
Aim: To synthesize the evidence on the efficacy and safety of using disinfection booths during the COVID-19 pandemic.
INFECTION CONTROL
1/25/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy, safety and rollout of COVID-19 vaccines.
1/25/21
Shrotri M, van Schalkwyk MCI, Post N, et al. | PLoS One
Aim: To summarize current understanding of the cellular response to SARSCoV-2 infection, specifically exploring the role that T cell-mediated immunity might play in resistance to severe infection, clinical and virological recovery, and long-term protection.
UPDATED
INFECTION CONTROL
1/25/21
Thapa BB, Shrestha D, Bista S, et al. | Surg J
Aim: To explore the consensus in modified standard urology care, that can be adopted and applied during COVID-19 and similar pandemic.
INFECTION CONTROL
1/22/21
Shams S, Rathore SS, Anvekar P, et al. | Dermatol Ther
Aim: To summarize clinical features, histopathological hallmarks, and possible pathology behind the maculopapular skin eruptions occurring in Covid-19 patients.
CLINICAL CHARACTERISTICS
1/22/21
Pajo AT, Espiritu AI, Apor ADAO, et al. | Neurol Sci
Aim: To review the currently available neuropathological data on COVID-19 including post-mortem findings of patients following a death from COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
1/22/21
Onorato D, Pucci M, Carpene G, et al. | Semin Thromb Hemost
Aim: To provide an updated overview on the interplay between statins and COVID-19, with particular focus on their potentially protective role against progression toward severe or critical illness and death.
CANDIDATE THERAPEUTICS
1/22/21
Lim AYH, GOH JL, Chua MCW, et al. | BMC Pulm Med
Aim: To assess the temporal progression of blood and radiology findings of patients with COVID-19.
CLINICAL CHARACTERISTICS
1/22/21
Oran DP, Topol EJ | Ann Intern Med
Aim: To estimate the proportion of persons infected with SARS-CoV-2 who never develop symptoms.
CLINICAL CHARACTERISTICS
1/21/21
Baradaran A, Malek A, Moazzen N, et al. | Iran J Allergy Asthma Immunol
Aim: To describe clinical manifestation and outcomes of MIS-C associated with COVID-19.
1/21/21
Ho JSY, Fernando DI, Chan MY, et al. | Ann Acad Med Singap
Aim: To investigate the relationship between COVID-19 and obesity.
1/21/21
Zare ME, Wang Y, Kansestani AN, et al. | Iran J Allergy Asthma Immunol
Aim: To determine the accuracies of white blood cell counts and inflammatory biomarkers for prognosis of COVID-19 patient's outcome by a DTA meta-analysis.
1/20/21
Zolopa C, Hoj S, Bruneau J, et al. | Int J Drug Policy
Aim: To review the impacts of Big Events with relevance to the COVID-19 pandemic on drug-related risk and harms and access to drug treatment and harm reduction services.
1/20/21
Fernando I, Perera J, Udawaththa I, et al. | SSRN
Aim: To systemize and organize the contemporary knowledge on stockpiling behavior during a Pandemic. 
MENTAL HEALTH
1/20/21
Mameli S, Marcialis MA, Bassareo PP, et al. | Panmiverva Medica
Aim: To review the evidence on the features of liver involvement and damage in the course of COVID-19.
CLINICAL CHARACTERISTICS
1/19/21
Kheirabadi D, Haddad F, Mousavi-Roknabadi RS, et al. | J Med Virol
Aim: To clarify which systematic reviews on COVID?19 treatment are based on high?value evidence.
1/19/21
von Philipsborn P, Biallas R, Burns J, et al. | BMJ Open
Aim: To assess the effects of prior and current use of NSAIDs in patients with acute viral respiratory infections on acute severe adverse events , on acute healthcare utilization, as well as on quality of life and long-term survival.
WHO COLLABORATIVE
1/19/21
Meng J, Ma Y, Jia J, et al. | Front Immunol
Aim: To compare the similarities and differences focusing on ferritin and cytokine levels between severe COVID-19 and active AOSD. 
1/19/21
Duz ME, Balci A, Menekse E | Tuberk Toraks
Aim: To review the evidence on D-dimer levels and mordidity and mortality in COVID-19 patients.
1/19/21
Kim J, Han SC, Jo HD, et al. | J Korean Med Sci
Aim: To investigate the factors that contribute to the inter-study variability in the prevalence of olfactory and gustatory dysfunction.
1/19/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the infectivity, virulence, and effectiveness of the current vaccines against the new SARS-CoV-2 variants.
1/19/21
Sahebi A, Nejati-Zarnaqi B, Moayedi S, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To review the evidence on the prevalence of anxiety and depression among healthcare workers during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
1/19/21
Cunarro-Lopez Y, Pintado-Recarte P, Cueto-Hernandez I, et al. | J Clin Med
Aim: To describe and analyze the profile of the obstetric patients according to the country of origin of the publication.
UPDATED
CLINICAL CHARACTERISTICS
1/19/21
Cavicchioli M, Ferrucci R, Guidetti M, et al. | Healthcare
Aim: To provide an evidence-based assessment of possible effects of the current COVID-19 quarantine on mental health.
MENTAL HEALTH
1/18/21
McClatchey K, Jackson T, Delaney B, et al. | J Allergy Clin Immunol Pract
Aim: To explore whether the information addresses relevant health actions to minimize the risk of contracting and spreading COVID-19, and encourages asthma self-management.
CLINICAL CHARACTERISTICS
1/18/21
Zeng W, Qi K, Ye M, et al. | Eur J Gastroenterol Hepatol
Aim: To explore the relationship between gastrointestinal symptoms and the severity of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/18/21
Martha JW, Wibowo A, Pranata R | Diabetes Metab Syndr
Aim: To evaluate the prognostic performance of hypocalcemia in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
1/18/21
Kow CS, Hasan SS | J Asthma
Aim: To review the evidence on the overall effect of the chronic use of inhaled corticosteroids on the clinical outcomes in patients with coronavirus disease 2019 (COVID-19). 
CANDIDATE THERAPEUTICS
1/18/21
Smit M, Marinosci A, Agoritsas T, et al. | Clin Microbiol Infect
Aim: To review the evidence on a pre- and post-exposure prophylactic (PrEP and PEP) candidate for COVID-19.
CANDIDATE THERAPEUTICS
1/16/21
Lin Y, Chen C, Wu S | J Med Internet Res
Aim: To review the efficiency and quality of data collection in the existing literature.
1/15/21
Shareef MA, Bashaiwth HM, AlAkbari AO, et al. | Avicenna J Med
Aim: To review the evidence on SARS-CoV-2 and HIV coinfection.
CLINICAL CHARACTERISTICS
1/15/21
Mohamadi M, Goodarzi A, Aryannejad A, et al. | Med J Islam Repub Iran
Aim: To review the evidence on SARS-CoV-2 infection complications in elderly individuals.
CLINICAL CHARACTERISTICS
1/15/21
Cirillo N, Bizzoca ME, Lo Muzio E, et al. | Acta Odontol Scand
Aim: To collect comprehensive data on the taste alterations prevalence worldwide and, precisely, in 16 countries.
1/15/21
Goldstein KM, Ghadimi K, Mystakelis H, et al. | VA Evidence Synthesis Program
Aim: To review the evidence on the risk of transmitting SARS-CoV-2, SARS, MERS, and influenza with administration of drugs via nebulizer
UPDATED
VA ESP
1/15/21
Xu W, Li X, Dozier M, et al. | J Glob Health
Aim: To investigate the extent of SARS-CoV-2 transmission in schools. 
UPDATED
INFECTION CONTROL
1/14/21
Zinellu A, Mangoini AA | J Clin Med
Aim: To review the evidence on the predictive role of the red blood cell distribution width (RDW), a routine hematological test, in patients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
1/14/21
???? P, ?????? H, ???????????? A, et al. | Russian Journal of Infection and Immunity
Aim: To determine the COVID-19 epidemiology, clinical features, diagnosis and treatment.
1/13/21
Hassanipour S, Faradonbeh SB, Momeni K, et al. | Int J Reprod Biomed
Aim: To investigate the clinical manifestation include signs and symptoms, laboratory results, and perinatal outcomes in pregnant women with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/13/21
Oshay RR, Chen MYC, Fields BKK, et al. | Clin Imaging
Aim: To conduct a comprehensive systematic review of all existing literature regarding imaging findings on chest CT and associated clinical features in pregnant patients diagnosed with COVID-19.
CLINICAL CHARACTERISTICS
1/13/21
Lee DS, Mirmirani P, McCleskey PE, et al. | Dermatol Online J
Aim: To identify case reports and case series characterizing cutaneous manifestations of confirmed COVID-19.
1/12/21
Soltani S, Tabibzadeh A, Zakeri A, et al. | Rev Neurosci
Aim: To systematically review the COVID-19 associated central nervous system manifestations, mental and neurological symptoms.
1/12/21
Killikelly C, Lenferink LIM, Xie H, et al. | J Loss Trauma
Aim: To review the evidence on the psychological symptoms in healthcare workers during the COVID-19 pandemic.
MENTAL HEALTH
1/11/21
Israfil SMH, Sarker MMR, Rashid PT, et al. | Front Public Health
Aim: To summarize the global clinical characteristics of the COVID-19 patients systematically and identify their diagnostic challenges to help the medical practitioners properly diagnose and for better management of COVID-19 patients. 
CLINICAL CHARACTERISTICS
1/11/21
Caristia S, Ferranti M, Skrami E, et al. | Epidemiol Prev
Aim: To describe and compare the effectiveness of national and local lockdowns in controlling the spread of COVID-19.
INFECTION CONTROL
1/11/21
Hariyanto TI, Japar KV, Kwenandar F, et al. | Am J Emerg Med
Aim: To evaluate the difference between these parameters in severe and nonsevere disease and to provide the optimal cutoff value for predicting severe disease.
CLINICAL CHARACTERISTICS
1/11/21
Johanna N, Citrawijaya H, Wangge G | J Public Health Res
Aim: To evaluate the effectiveness of mass testing, lockdown, or a combination of both to control COVID-19 pandemic.
UPDATED
INFECTION CONTROL
1/11/21
Zhao X, Gang X, He G, et al. | Front Endocrinol
Aim: To compare the impacts of obesity on the severity and mortality of influenza and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/11/21
Fan S, Guan J, Cao L, et al. | Asian J Psychiatr
Aim: To investigate and monitor the mental health status of pregnant women during the COVID-19 pandemic.
MENTAL HEALTH
1/11/21
Kahil K, Cheaito MA, El Hayek R, et al. | Asian J Psychiatr
Aim: To synthesize descriptive and analytic evidence of suicide and suicide-related outcomes (ideations, intent, attempt, or completion) during major international respiratory outbreaks (COVID-19, MERS, SARS, and influenza A) in the recent history.
MENTAL HEALTH
1/11/21
Syeda HB, Syed M, Sexton KW, et al. | JMIR Med Inform
Aim: To conduct a systematic literature review on the role of ML as a comprehensive and decisive technology to fight the COVID-19 crisis in the arena of epidemiology, diagnosis, and disease progression.
UPDATED
1/10/21
Lewis A, Frontera J, Placantonakis DG, et al. | J Neurol Sci
Aim: To review the literature on cerebrospinal fluid (CSF) testing in patients with COVID-19 for evidence of viral neuroinvasion by SARS-CoV-2.
CLINICAL CHARACTERISTICS
1/9/21
Mansourian M, Ghandi Y, Habibi D, et al. | Arch Pediatrie
Aim: To provide a meta-analysis of previously published papers on the COVID-19-related clinical features and laboratory findings in children.
CLINICAL CHARACTERISTICS
1/9/21
Wittenberg E, Goldsmith JV, Chen C, et al. | Patient Educ Couns
Aim: To determine the content of provider communication resources and peer-reviewed articles on COVID-19 communication in order to identify opportunities for developing future COVID-19 communication curricula and support tools.
1/8/21
Aminian A, Tu C, et al. | Obes Surg
Aim: To measure the association between history of bariatric surgery and the severity of COVID-19.
CLINICAL CHARACTERISTICS
1/8/21
Joo JY, Liu M | Int Nurs Rev
Aim: To identify and synthesize qualitative studies of frontline nurses’ experiences and challenges when caring for patients with COVID?19 in hospitals.
UPDATED
MENTAL HEALTH
1/8/21
Abubakar AR, Sani IH, Godman B, et al. | Infect Drug Resist
Aim: To summarize some evidence-based therapeutic options for COVID-19 infection.
1/7/21
Lin C, Tu P, Beitsch LM | Vaccines
Aim: To compare trends and synthesize findings in vaccination receptivity over time across US and international polls, assess survey design influences and evaluate context to inform policies and practices.
INFECTION CONTROL
1/7/21
Cuadra-Martínez D, Castro-Carrasco PJ, Sandoval-Díaz J, et al. | Rev Med Chil
Aim: To conduct a systematic review on psychological behavior in the context of pandemic scenarios during the twenty-first century. 
MENTAL HEALTH
1/7/21
Deng Y, Chen Y, Zhang B | Asian J Psychiatr
Aim: To evaluate the prevalence of depression and anxiety among general public and healthcare workers during COVID-19 in China and the changes of prevalence before and after the peak of the epidemic occurred.
MENTAL HEALTH
1/7/21
Lukito AA, Pranata R, Henrina J, et al. | Diabetes Metab Syndr
Aim: To review the evidence on metformin consumption and mortality in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
1/6/21
Islam MM, Poly TN, Walther BA, et al. | Front Med
Aim: To assess clinical manifestations and neonatal outcomes of pregnant women with COVID-19.
CLINICAL CHARACTERISTICS
1/6/21
Badawi A, Vasileva D | World J Clin Cases
Aim: To analyze and compare the profile of COVID-19 cases between China and North America as two regions that differ in many environmental, host and healthcare factors related to disease risk.
CLINICAL CHARACTERISTICS
1/6/21
Santos REA, da Silva MG, do Monte Silva MCB, et al. | Am J Otolaryngol
Aim: To conduct a systematic review of the literature to investigate the time of onset and duration of symptoms of loss of smell and taste in patients diagnosed with COVID-19.
CLINICAL CHARACTERISTICS
1/6/21
Andrade BS, Rangel FS, Santos NO, et al. | Front Pharmacol
Aim: To review the evidence on drug candidates, potentially approved to be used as new options for SARS-CoV-2 prophylaxis clinical trials and medical protocols. 
CANDIDATE THERAPEUTICS
1/6/21
Agrawal V, Yadav SK, Agarwal P, et al. | Indian Journal of Surgery
Aim: To appraise the quality of appropriate PPE recommendations and propose a strategy to optimize the PPE usage. 
INFECTION CONTROL
1/6/21
Lewis K, Chaudhuri D, Alshamsi F, et al. | PLoS One
Aim: To determine the efficacy and safety of hydroxychloroquine as prophylaxis for COVID-19.
CANDIDATE THERAPEUTICS
1/6/21
Zaffanello M, Piacentini G, Nosetti L, et al. | Transfus Apher Sci
Aim: To review the literature and ongoing clinical trials on convalescent plasma therapy in pediatric patients with COVID-19. 
CANDIDATE THERAPEUTICS
1/5/21
Hariyanto TI, Hardyson W, Kurniawan A | Drug Res
Aim: To give clear evidence regarding the potential benefit and safety of tocilizumab in improving the outcome of COVID-19 patients.
CANDIDATE THERAPEUTICS
1/5/21
Mishra P, Tomar A, Kumar A, et al. | Saudi Journal of Anaesthesia
Aim: To review the evidence on effective pain management in pediatric patients suffering from SARS-CoV-2 virus symptoms.
1/5/21
Kansagara D, Mackey K, Vela K, et al. | Ann Intern Med
Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.
UPDATED
WHO COLLABORATIVE
VA ESP
1/5/21
Benito DA, Bestourous DE, Tong JY, et al. | Otolaryngol Head Neck Surg
Aim: To determine the cumulative incidences of decannulation and mechanical ventilation weaning in patients with coronavirus disease 2019 (COVID-19) who have undergone a tracheotomy. 
CLINICAL CHARACTERISTICS
1/5/21
Hashemi-madani N, Emami Z, Janani L, et al. | Clin Imaging
Aim: To assess the relationship between different chest CT features and severity of clinical presentation in COVID-19.
CLINICAL CHARACTERISTICS
1/4/21
Alawna M, Amro M, Mohamed AA | Eur Rev Med Pharmacol Sci
Aim: To systematically analyze the effects of aerobic exercise on immunological biomarkers to provide safe aerobic exercise recommendations and specifications for patients with COVID-19.
CANDIDATE THERAPEUTICS
1/4/21
Post N, Eddy D, Huntley C, et al. | PLoS One
Aim: To comprehensively evaluate the evidence describing the antibody response to SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Rahimi NR, Fouladi-Fard R, Aali R, et al. | Environ Res
Aim: To highlight how the virus is impacted by the environment and how the virus has impacted the environment.
1/4/21
Rada G, Corbalan J, Rojas P, et al. | Medwave
Aim: To provide a timely, rigorous and continuously updated summary of the available evidence on the role of cell-based therapies in the treatment of patients with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
1/4/21
Khamis AH, Jaber M, Azar A, et al. | J Formos Med Assoc
Aim: To systematically review all COVID-19 publications to summarize the clinical features, assess comorbidities, prevalence, and disease outcomes.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Kim MS, An MH, Kim WJ, et al. | PLoS One
Aim: To evaluate the comparative efficacy and safety of pharmacological interventions used in treating COVID-19 and form a basis for an evidence-based guideline of COVID-19 management by evaluating the level of evidence behind each treatment regimen in different clinical settings. 
UPDATED
CANDIDATE THERAPEUTICS
1/4/21
Han Q, Guo M, Zheng Z, et al. | Front Pharmacol
Aim: To assess the safety and efficacy of anti-IL-6 signaling (anti-IL6/IL-6R/JAK) agents on COVID-19.
CANDIDATE THERAPEUTICS
1/4/21
Choupoo NS, Das SK, Haldar R, et al. | Indian J Crit Care Med
Aim:  To test the efficacy of different therapeutic options currently available for treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/4/21
Cascino F, Hoxhaj I, Zace D, et al.  | BMJ Glob Health
Aim: To identify healthcare systems interventions, experiences and recommendations that have been used to manage different respiratory viral infections outbreaks in the past.
UPDATED
1/4/21
Desai A, Gupta R, Advani S, et al. | Cancer
Aim: To assess the overall mortality in this population through a meta?analysis of published data on COVID?19 and cancer.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Fu L, Liu X, Su Y, et al. | Clin Cardiol
Aim: To investigate prevalence of cardiac injury and its impact on the outcomes in patients with COVID?19.
CLINICAL CHARACTERISTICS
1/4/21
Del Zompo F, De Siena M, Ianiro G, et al. | Eur Rev Med Pharmacol Sci
Aim: To systematically review the prevalence of liver involvement in patients with SARS-CoV-2 infection at their hospital admission, and its correlation with disease severity and clinical outcomes in patients with or without pre-existing chronic liver disease.
CLINICAL CHARACTERISTICS
1/4/21
Lee KH, Kim SJ, Hong SH, et al. | Eur Rev Med Pharmacol Sci
Aim: To analyze the same clinical issues through an improved research method and to find out the differences from the retracted papers.
1/4/21
Liu H, Yang D, Chen X, et al.  | Cancer Med
Aim: To qualify the potential effects of anticancer therapies on the clinical outcomes, such as mortality, admission to the intensive care unit (ICU), and the severity of COVID?19, in patients with cancer infected with COVID?19.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Dillman A, Zoratti MJ, Park JJH, et al. | Infect Drug Resist
Aim: To summarize and characterize research efforts with respect to the different stages of disease progression.
1/3/21
Cai R, Zhang J, Zhu Y, et al. | Int Urol Nephrol
Aim: To conduct a literature review and meta-analysis to understand the frequency of mortality among CKD patients infected with COVID-19.
CLINICAL CHARACTERISTICS
1/3/21
de Souza DB, de Oliveira Andrade A, Milagre ST, et al. | Research on Biomedical Engineering
Aim: To carry out a systematic review of the advantages and disadvantages of possible solutions in oxygenation support.
CANDIDATE THERAPEUTICS
1/2/21
Farrukh L, Mumtaz A, Sana MK | Rev Med Virol
Aim: To review the evidence on potential reasons why the results of the SARS?CoV?2 RT?PCR tests were positive again in recovered patients.
1/2/21
Liu N, Sun J, Wang X, et al. | Int J Infect Dis
Aim: To assess the association between low vitamin D status and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/2/21
Salehi M, Amanat M, Mohammadi M, et al. | J Affect Disord
Aim: To assess the prevalence of PTSD related symptoms in coronavirus outbreaks.
MENTAL HEALTH
1/1/21
Danet AD | Med Clin
Aim: To find out the psychological impact among first-line healthcare personnel in caring for patients with SARS-CoV-2 and to compare it with the rest of healthcare professionals.
MENTAL HEALTH
1/1/21
O'Leary T | J Molecular Diag
Aim: To better understand the relative performance characteristics of saliva and upper airway samples.
DIAGNOSTICS
12/31/20
Chowdhary A, Subedi R, Tandon M | Brain Sci
Aim: To collect, analyze, and summarize the neurological findings in the MRI among patients with COVID-19
CLINICAL CHARACTERISTICS
12/31/20
Tian T, Huo X | J Infect Dev Ctries
Aim: To review the evidence on the secondary attack rate of SARS-CoV-2.
CLINICAL CHARACTERISTICS
12/30/20
Mehraeen E, Alinaghi SAS, Nowroozi A, et al. | Indian Heart J
Aim: To pinpoint different observed ECG findings and discuss their clinical significance.
CLINICAL CHARACTERISTICS
12/30/20
McEwan T, Robinson PC | Semin Arthritis Rheum
Aim: To systematically examine infectious adverse events associated with colchicine usage and the clinical use of colchicine for infectious diseases.
CANDIDATE THERAPEUTICS
12/30/20
Lai X, Liu J, Zhang T, et al. | BMJ Open
Aim: To systematically assess the clinical, laboratory and imaging predictors as well as prediction models for severe or critical illness and mortality in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/30/20
de Oliveira TF, de Oliveira Rocha CA, dos Santos AGG, et al. | Braz J Cardiovasc Surg
Aim: To systematically review the literature on the use of extracorporeal membrane oxygenation (ECMO) in patients with coronavirus disease 2019 (COVID-19).
CANDIDATE THERAPEUTICS
12/30/20
Dorrell R, Dourgherty MK, Barash EL, et al. | JGH Open
Aim: To characterize the prevalence of gastrointestinal (GI) and hepatic involvement in COVID?19 and specifically assess the prevalence of GI symptoms in isolation.
UPDATED
CLINICAL CHARACTERISTICS
12/30/20
Verdejo C, Vergara-Merino L, Meza N, et al. | Medwave
Aim: To provide a timely, rigorous, and continuously updated summary of the evidence available on the role of macrolides for treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
12/30/20
Mondal R, Ganguly U, Deb S, et al. | J Neurovirol
Aim: To summarise the clinical profile, investigations and radiological findings among patients with SARS-CoV-2 associated meningoencephalitis.
UPDATED
CLINICAL CHARACTERISTICS
12/30/20
Brown WA, Moore EM, Watters DA | ANZ J Surg
Aim: To estimate the effect size of coronavirus disease 2019 (COVID-19) on post-operative mortality.
CLINICAL CHARACTERISTICS
12/30/20
Maharaj S, Alvarez MB, Mungul S, et al. | Laryngoscope Investig Otolaryngol
Aim: To describe otologic dysfunction in patients with the novel SARS?CoV?2.
CLINICAL CHARACTERISTICS
12/30/20
Al Maqbali M, Al Sinani M, Al-Lenjawi B | J Psychosom Res
Aim: To ascertain the present impact of the COVID-19 outbreak on the prevalence of stress, anxiety, depression and sleep disturbance among nurses.
UPDATED
MENTAL HEALTH
12/30/20
Panda PK, Gupta J, Chowdhury SR, et al. | J Trop Pediatr
Aim: To provide a pooled estimate of the prevalence of various psychological and behavioral symptoms/disorders in children and adolescents up to 18?years of age during this pandemic.
MENTAL HEALTH
12/30/20
SeyedAlinaghi S, Oliaei S, Kianzad S, et al. | World J Virol
Aim: To summarize the recent findings and reports of COVID-19 reinfection in patients previously reCoVered from the disease.
CLINICAL CHARACTERISTICS
12/30/20
Verdugo-Paiva F, Acuna MP, Sola I, et al. | Medwave
Aim: To provide a timely, rigorous and continuously updated summary of the evidence available on the role of remdesivir in the treatment of patients with COVID-19.
12/30/20
Callus E, Bassola B, Fiolo V, et al. | Front Psychol
Aim: To identify the most effective stress reduction techniques for health care providers dealing with patients infected with severe coronavirus (SARS, MERS, and COVID-19).
UPDATED
MENTAL HEALTH
12/30/20
Parsay S, Vosoughi A, Khabbaz A, et al. | J Stroke Cerebrovasc Dis
Aim: To investigate the incidence of ischemic CVA and the mortality due to it in the setting of COVID-19.
CLINICAL CHARACTERISTICS
12/29/20
Chou R, Dana T, Jungbauer R, et al. | Ann Intern Med
Aim: To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.
UPDATED
12/28/20
Pranata R, Henrina J, Lim MA, et al. | Arch Gerontol Geriatr
Aim: To quantify the dose-response relationship between CFS and mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
12/28/20
Hassani NS, Shojaee A, Khodaprast Z, et al. | J Intensive Care Med
Aim: To investigate the echocardiographic features of cardiac injury related to COVID-19 and their prognostic value.
CLINICAL CHARACTERISTICS
12/28/20
Polychronis G, Roupa Z | J Public Aff
Aim: To review the evidence on health care workers' knowledge level during the spread of COVID-19 and their perception of the risk related to the COVID-19 pandemic.
INFECTION CONTROL
12/28/20
Aziz M, Goyal H, Haghbin H, et al. | Am J Med Sci
Aim: To evaluate the prevalence of “loss of smell” in COVID-19 as well as its utility for prognosticating the disease severity.
CLINICAL CHARACTERISTICS
12/28/20
Clement ND, Ng N, Simpson CJ, et al. | Bone Joint Res
Aim: To assess: 1) the prevalence of COVID-19 in hip fracture patients during the first wave of the pandemic; 2) the associated rate and risk of mortality compared to those without COVID-19; 3) the demographics associated with COVID-19-positive patients; 4) the time from the day of admission to diagnosis of COVID-19; and 5) length of follow-up after a diagnosis of COVID-19.
CLINICAL CHARACTERISTICS
12/23/20
Prendki V, Tau N, Avni T, et al. | BMC Geriatr
Aim: To examine the participation of elderly patients in therapeutic or prophylactic trials on COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
12/23/20
Birgand G, Peiffer-Smadja N, Fournier S, et al. | JAMA Netw Open
Aim: To review current evidence on air contamination with SARS-CoV-2 in hospital settings and the factors associated with contamination, including viral load and particle size.
INFECTION CONTROL
12/23/20
 | European Centre for Disease Prevention and Control
Aim: To provide an update on the knowledge surrounding the role of children in the transmission of SARS-CoV-2 and the role of schools in the COVID-19 pandemic, based on the experience in the EU from August–December, 2020. 
INFECTION CONTROL
12/23/20
Bhuiyan MU, Stiboy E, Hassan MZ, et al. | Vaccine
Aim: To review the evidence on the epidemiological and clinical characteristics of COVID-19 infection in children under five years.
UPDATED
CLINICAL CHARACTERISTICS
12/23/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the use of ivermectin for prophylaxis or treatment of COVID-19.
12/23/20
Kubota T, Gajera PK, Kuroda N | Epilepsy Behav
Aim: To perform a systematic review and meta-analysis to summarize and quantitatively evaluate the electroencephalogram (EEG) findings in patients with coronavirus disease 2019 (COVID-19).
12/23/20
Scheen AJ | Diabetes Metab
Aim: To investigate the impact of previous statin therapy in patients hospitalized for COVID-19.
CLINICAL CHARACTERISTICS
12/22/20
Ghazy RM, Almaghraby A, Shaaban R, et al. | Sci Rep
Aim: To review the evidence on the effectiveness and safety of either CQ or HCQ alone or in combination with AZM in treating COVID-19.
CANDIDATE THERAPEUTICS
12/22/20
Sun F, Zhu J, Tao H, et al. | J Psychosom Obstet Gynaecol
Aim: To review the evidence on mental health in pregnant and delivery women during the COVID-19 pandemic.
MENTAL HEALTH
12/22/20
Luo Y, Chua CR, Xiong Z, et al. | Front Psychiatry
Aim: To review the evidence on the impact of viral respiratory epidemics, including coronavirus disease 2019 (COVID-19), on mental health among different population groups, drawing on their insights for recommendations for the current COVID-19 pandemic.
MENTAL HEALTH
12/22/20
Piombino P, Troise S, Vargas M, et al. | Eur Rev Med Pharmacol Sci
Aim: To analyze the scientific literature identifying the indications for tracheostomy and safety precautions to reduce contamination.
CANDIDATE THERAPEUTICS
12/22/20
Fiest KM, Krewulak KD, Plotnikoff KM, et al. | BMC Med
Aim: To evaluate the validity of published triage protocols and the mortality prediction embedded within them to help inform health system-decision-making.
12/22/20
Oikonomidi T, Boutron I, Pierre O, et al. | BMC Med
Aim: To describe the proportion of evidence on the effect of interventions for COVID-19 from preprints and journal articles and map changes in evidence between and within different sources reporting on the same study.
CANDIDATE THERAPEUTICS
12/22/20
Neef V, Buxmann H, Rabenau HF, et al. | Pediatr Neonatal
Aim: To characterize a large number of neonates delivered by rRT-PCR confirmed SARS-CoV-2 positive mothers.
CLINICAL CHARACTERISTICS
12/22/20
Wang Y, Huo P, Dai R, et al. | Int Immunopharmacol
Aim: To evaluate the existing evidence and experience related to CP immunotherapy for COVID-19.
CANDIDATE THERAPEUTICS
12/22/20
Fabrizi F, Alfieri CM, Cerutti R, et al. | Pathogens
Aim: To evaluate the frequency of AKI and dialysis requirement in patients who underwent hospitalization due to COVID-19.
CLINICAL CHARACTERISTICS
12/22/20
Rocha APD, Atallah ÁN, Pinto ACPN, et al. | Sao Paulo Med J
Aim: To assess whether patients undergoing pharmacological treatment for IMID present higher risk of worse outcomes when diagnosed with COVID-19.
CLINICAL CHARACTERISTICS
12/22/20
Clark M, Loshak H, Farrah K | CADTH
Aim: To review the evidence on the use of COVID-19 mRNA vaccines on patients with cancer or who are immunocompromised.
12/22/20
Siemieniuk RAC, Bartoszko JJ, Ge L, et al. | BMJ
Aim: To compare the effects of treatments for coronavirus disease 2019 (covid-19).
UPDATED
CANDIDATE THERAPEUTICS
12/22/20
Rattka M, Dreyhaupt J, Winsauer C, et al. | Heart
Aim: To assess the mortality of patients with STEMI admitted during the COVID-19 pandemic.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Bae S, Kim SR, Kim M, et al.  | Heart
Aim: To estimate the prevalence and risk factors for CVD among patients with COVID-19 in different age groups.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Sarkar S, Khanna P, Singh A | J Med Virol
Aim: To evaluate the consequence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in patients with concurrent co-infections based on the publications reported to date.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Octavius GS, Silviani FR, Lesmandjaja A, et al. | Middle East Current Psychiatry
Aim: To analyze the impact of COVID-19 towards adolescents’ mental health.
MENTAL HEALTH
12/22/20
Tyrrell CSB, Mytton OT, Gentry SV, et al. | Thorax
Aim: To provide acute insights into the guidance on which patients are treated in ICU and receive ventilation during periods of high demand for ICU capacity during the COVID-19 pandemic.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Mathioudakis AG, Fally M, Hashad R, et al. | Life
Aim: To describe the outcomes evaluated in 415 RCTs on the management of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Rabbani G, Islam SMS, Rahman MA, et al. | Expert Rev Respir Med
Aim: To investigate COVID-19 mortality and severity among patients with pre-existing COPD.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Rodrigues C, Baía I, Domingues R, et al. | Front Public Health
Aim: To review knowledge on the impact of COVID-19 on pregnancy and describe the outcome of published cases of pregnant women diagnosed with COVID-19, as well as the characteristics of COVID-19 positive women who delivered in Portugal by 31 of March 2020. 
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Santabárbara J, Lasheras I, Lipnicki DM, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To conduct a systematic review and meta-analysis to ascertain the impact of the COVID-19 outbreak on the prevalence of anxiety in the general population.
MENTAL HEALTH
12/22/20
July J, Pranata R | Geriatr Gerontol Int
Aim: To discover whether age, sex and other comorbidities might affect the association between dementia and mortality.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Islam MA, Alam SS, Kundu S, et al. | Front Neurol
Aim: To conduct a comprehensive systematic review and meta-analysis to estimate the overall pooled prevalence of headache in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Violant-Holz V, Gallego-Jimenez MG, Gonzalez-Gonzalez CS, et al. | Int J Environ Res Public Health
Aim: To analyze the extent to which engaging in physical activity during the COVID-19 pandemic affected adults’ psychological health.
MENTAL HEALTH
12/22/20
West E, Moore K, Kupeli N, et al. | Age Aging
Aim: To explore key factors that influence place of care and place of death decisions in older adults.
12/22/20
Lee MMY, Docherty KF, Sattar N, et al. | Eur Heart J Cardiovasc Pharmacother
Aim: To provide summary odds ratio (OR) estimates for associations between treatment with (vs. without) renin-angiotensin system (RAS) blockers and risk of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection and coronavirus disease 2019 (CoViD-19) severity (including case-fatality) in patients with hypertension, and in all patients (irrespective of hypertension).
CANDIDATE THERAPEUTICS
12/22/20
Viner RM, Ward J, Hudson L, et al. | Arch Dis Child
Aim: To undertake a systematic review of reviews of the prevalence of symptoms and signs of COVID-19 in those aged under 20 years.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Subsoontorn P, Lohitnavy M, Kongkaew C | Sci Rep
Aim: To determine the accuracy of nucleic acid point-of-care diagnosis for human coronaviruses, particularly, SARS-CoV, MERS-CoV and SARS-CoV-2.
UPDATED
DIAGNOSTICS
12/22/20
Wang B, Luo Q, Zhang W, et al. | Kidney Blood Press Res
Aim: To evaluate the association of chronic kidney disease (CKD) and acute kidney injury (AKI) with the clinical prognosis of patients with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
12/22/20
Salari N, Khazaie H, Hosseinian-Far A, et al. | Hum Resour Health
Aim: To systematically review and determine the prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients.
MENTAL HEALTH
12/22/20
Pillai K, Hewage S, Harky A | J Med Ultrasound
Aim: To review the evidence on the potential role of the lung ultrasound to evaluate its benefits and potential roles to compare it to the current gold standard of computed tomography.
DIAGNOSTICS
12/18/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the impact of COVID-19 and related public health measures on household food security.
UPDATED
12/18/20
Yan H, Ding Y, Guo W | Front Psychol
Aim: To quantify the influence of the COVID-19 pandemic on the mental health of pregnant and postpartum women, and to explore the specific vulnerable groups among this population of women.
UPDATED
MENTAL HEALTH
12/18/20
Wenjing L, Yuanzheng F, Li JY, et al. | Aging
Aim: To review the evidence on the safety and efficacy of CP transfusion in SARS-CoV-2-infected patients.
CANDIDATE THERAPEUTICS
12/18/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the role of daycares and schools in the transmission of COVID-19.
UPDATED
12/17/20
Johnson BA, Waddimba AC, Ogola GO, et al. | Am J Surg
Aim: To investigate if surgical delays impact survival for breast, lung and colon cancers.
INFECTION CONTROL
12/17/20
Zafari M, Rad MTS, Mohseni F, et al. | Hemoglobin
Aim: To determine mortality and morbidity of infected ?-thal patients with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
12/17/20
van Paassen J, Vos JS, Hoekstra EM, et al. | Crit Care
Aim: To evaluate the effect of corticosteroids on mortality, viral clearance and secondary outcomes in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
12/17/20
Wan J, Wang X, Su S, et al. | JGH Open
Aim: To investigate the exact prevalence of digestive symptoms and liver injury in COVID?19 patients and compare the difference between patients with and without digestive symptoms. 
CLINICAL CHARACTERISTICS
12/17/20
Lewinski AA, Rushton S, Van Voorhees E, et al. | Res Nurs Health
Aim: To review the evidence on the practices that impact the implementation of RT for adults seeking clinical care advice.
INFECTION CONTROL
12/17/20
Suh YJ, Hong H, Ohana M, et al. | Radiology
Aim: To conduct meta-analysis of the study-level incidence of PE and DVT and to evaluate the diagnostic accuracy of D-dimer tests for PE from multicenter individual patient data. 
CLINICAL CHARACTERISTICS
12/17/20
Arieta-Miranda J, Alcaychahua ABS, Santos GMP, et al  | Heliyon
Aim: To evaluate the quality of the CPG for the management of paediatric dental emergencies, published in the period 2000–2020 and applicable to the context of pandemic, by using the AGREE II tool.
UPDATED
INFECTION CONTROL
12/17/20
Silver SA, Beaubien-Souligny W, Shah PS, et al. | Kidney Med
Aim: To determine the pooled prevalence of AKI and KRT among hospitalized patients with COVID-19.
CLINICAL CHARACTERISTICS
12/16/20
Noorimotlagh Z, Jaafarzadeh N, Martínez SS, et al. | Environ Res
Aim: To systematically collect all experimental studies related to airborne transmission of SARS-CoV-2 in indoor air environments.
INFECTION CONTROL
12/16/20
Thakkar S, Arora S, Kumar A, et al. | Clin Med Insights Cardiol
Aim: To provide a foundation for understanding the CV manifestations and outcomes of COVID-19.
CLINICAL CHARACTERISTICS
12/16/20
Lazarus G, Audrey J, Kharisma Wangsaputra V, et al. | Diabetes Res Clin Pract
Aim: To investigate the prognostic value of admission blood glucose (BG) in predicting COVID-19 outcomes, including poor composite outcomes (mortality/severity), mortality, and severity.
CLINICAL CHARACTERISTICS
12/16/20
Madewell ZJ, Yang Y, Longini IM, et al. | JAMA Netw Open
Aim: To examine evidence for household transmission of SARS-CoV-2, disaggregated by several covariates, and to compare it with other coronaviruses.
UPDATED
INFECTION CONTROL
12/16/20
Liu S, Cao Y, Du T, et al. | J Allergy Clin Immunol Pract
Aim: To investigate the asthma prevalence among COVID-19 patients and compare outcomes between asthma and non-asthma patients.
UPDATED
CLINICAL CHARACTERISTICS
12/16/20
Wu T, Jia X, Shi H, et al. | J Affect Disord
Aim: To provide a comprehensive perspective of the prevalence mental health problems during the COVID-19 pandemic and identify high risk groups of mental health problems related to COVID-19 pandemic.
UPDATED
MENTAL HEALTH
12/16/20
Zhang R, Ni L, Di X, et al. | J Vasc Surg Venous Lymphat Disord
Aim: To identify the prevalence of VTE, PE, and DVT in consecutive hospitalized patients, ICU patients, and non-ICU patients with COVID-19 by a meta-analysis based on currently available clinical studies.
CLINICAL CHARACTERISTICS
12/16/20
Samaranayake LP, Fakhruddin KS, Buranawat B, et al. | Acta Odontal Scand
Aim: To evaluate available data on three major measures: rubber dam application, pre-procedural oral rinse, and high-volume evacuators (HVE) aimed at reducing bio-aerosols.
INFECTION CONTROL
12/16/20
Liu N, Zhang T, Ma L, et al. | Blood Rev
Aim: To elucidate the association between ABO blood group and increased COVID-19 morbidity and mortality.
CLINICAL CHARACTERISTICS
12/16/20
Li X, Xu W, Dozier M, et al. | J Glob Health
Aim: To investigate the role of children in the transmission of SARS-CoV-2. 
INFECTION CONTROL
12/16/20
Khalili M, Chegeni M, Javadi S, et al. | Ther Adv Respir Dis
Aim: To provide a succinct summary of the findings of systematic reviews on different pharmacological and non-pharmacological therapeutic interventions for COVID-19.
CANDIDATE THERAPEUTICS
12/16/20
Cowling T, Graves E, Loshak H | CADTH
Aim: To explore what we know about virus-neutralizing monoclonal antibodies, their mechanism of action and how they are administered, and which virus-neutralizing monoclonal antibodies are in clinical development for SARS-CoV-2 infection.
12/15/20
Moazzami B, Chaichian S, Kasaeian A, et al. | PLoS One
Aim: To assess the association of metabolic risk factors and risk of Covid-19.
CLINICAL CHARACTERISTICS
12/15/20
Siow I, Lee KS, Zhang JJY, et al. | J Stroke Cerebrovasc Dis
Aim: To evaluate the epidemiology, clinical course, and outcomes of patients who suffer from stroke as a complication of COVID-19.
CLINICAL CHARACTERISTICS
12/14/20
Maples LS | Int J Nurs Pract
Aim: To determine the effectiveness of quarantine on coronavirus outbreaks to support the WHO quarantine recommendation. 
INFECTION CONTROL
12/14/20
Gallagher JE, Sukriti KC, Johnson IG, et al. | BDJ Open
Aim: To review the evidence on the pattern of aerosol spread and settle relevant to oral surgery in dental surgery.
UPDATED
12/14/20
Nobari NN, Seirafianpour F, Mashayekhi F, et al. | Dermatol Ther
Aim: To review the evidence on treatment-related mucocutaneous drug reactions of COVID-19.
CANDIDATE THERAPEUTICS
12/14/20
Ojha V, Verma M, Pandey NN, et al.  | J Thorac Imaging
Aim: To assess the important imaging features on CMR in patients diagnosed with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/14/20
Piscoya A, Ng-Sueng LF, del Riego AP, et al. | PLoS One
Aim: To evaluate the efficacy and safety of remesdivir for the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
12/14/20
Kaushal K, Sarma P, Rana SV, et al. | J Biomol Struct Dyn
Aim: To evaluate the role of AI in drug repurposing, novel drug discovery, vaccine and antibody development for the therapeutics of COVID-19.
CANDIDATE THERAPEUTICS
12/14/20
Arevalo Rodriguez I, Buitrago Garcia D, Simancas Racines D, et al.  | PLoS One
Aim: To review and critically appraise evidence about the proportion of RT-PCR false-negatives at initial testing for COVID-19. 
UPDATED
DIAGNOSTICS
12/14/20
Liao S, Shao S, Cheng C, et al. | Crit Care
Aim: To review the evidence on the incidence and mortality rates after incident arrhythmia in COVID-19 patients.
CLINICAL CHARACTERISTICS
12/14/20
Al-Benna S | Ann Burns Fire Disasters
Aim: To identify the optimal protection measures during the COVID-19 pandemic and provide guidance of protective measures for burn surgeons.
INFECTION CONTROL
12/14/20
Kaprin AD, Fedenko AA, Polyakov AA, et al. | Khirurgiia
Aim: To review the evidence on surgical management and preoperative screening of cancer patients within the COVID-19 pandemic, as well as prevention of SARS-CoV-2 transmission and resumption of elective surgery.
INFECTION CONTROL
12/14/20
Novelli L, Motta F, De Santis M, et al. | J Autoimmun
Aim: To evaluate the COVID-19-related autoimmune/rheumatic disorders.
CLINICAL CHARACTERISTICS
12/12/20
Badawi AE, Elsheikh SS, Addeen SZ, et al. | J Curr Ophthalmol
Aim: To discuss the ocular manifestations provoked by novel coronavirus 2019 (COVID-19) disease in humans, the natural history of the disease in the eye, and its treatment.
12/11/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on risk factors are associated with COVID-19 outbreaks and mortality in LTC facilities and what strategies mitigate risk.
UPDATED
12/11/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on how and by whom COVID-19 is introduced and transmitted within acute care settings.
12/10/20
 | NSW Health COVID-19 Critical Intelligence Unit
12/10/20
Levin AT, Hanage WP, Owusu-Boaitey N, et al. | Eur J Epidemiol
Aim: To assess the age specificity of the infection fatality rate (IFR) for COVID-19 using seroprevalence results from eight national studies (Belgium, England, Hungary, Italy, Netherlands, Portugal, Spain, and Sweden), fifteen seroprevalence studies of specific locations in Europe and the United States, and three countries (Iceland, New Zealand, and Republic of Korea) that have engaged in comprehensive tracking and tracing of COVID-19 infections.
UPDATED
12/10/20
Liu N, Sun J, Wang X, et al. | J Alzheimers Dis
Aim: To investigate the impact of pre-existing dementia comorbidities on COVID-19.
12/9/20
Kondylakis H, Katehakis DG, Kouroubali A, et al. | J Med Internet Res
Aim: To shed light into studies found in the scientific literature that have used and evaluated mobile apps for the prevention, management, treatment, or follow-up of COVID-19.
12/9/20
 | NSW Health COVID-19 Critical Intelligence Unit
12/9/20
El Keshky MES, Basyouni SS, Al Sabban AM | Front Psychol
Aim: To evaluate the impact of COVID-19 on the psychology of sustainability (quality of life), on sustainable development, and on the global economy. 
12/9/20
Sriwastava S, Kataria S, Tandon M, et al. | J Neurol Sci
Aim: To compare and summarize the demographics, clinical features, Brighton criteria, immunological and laboratory findings with a focus on modified Erasmus GBS Outcome Score (mEGOS) in SARS-CoV-2 patients with GBS and its variants.
12/9/20
Vancsa S, Hegyi PJ, Zadori N, et al. | Front Med
Aim: To evaluate the prognostic value of on-admission liver function tests and pre-existing liver diseases on the clinical course of coronavirus disease 2019 (COVID-19).
UPDATED
12/9/20
Putko RM, Bedrin MD, Clark DM, et al. | J Clin Orthop Trauma
Aim: To identify risk factors, comorbidities, case characteristics, and treatment strategies to better understand the nature of this disease and its effects on the extremities.
12/9/20
Prakash A, Singh H, Kaur H, et al. | Indian J Psychiatry
Aim: To evaluate the efficacy and safety of FPV in published literature.
12/9/20
Shamshirian A, Hessami A, Heydari K, et al. | Ann Acad Med Singap
Aim: To examine the effectiveness of hydroxychloroquine in treatment of COVID-19.
UPDATED
12/9/20
Fligor SC, Tsikis ST, Wang S, et al. | J Thorac Dis
Aim: To synthesize the available literature on time to surgery and its impact on outcomes along with a critical appraisal of the released triage guidelines in the United States.
12/8/20
Keshavarz P, Rafiee F, Kavandi H, et al. | Clin Imaging
Aim: To review the clinical and radiologic features of GI ischemia and its related complications in thirty-one COVID-19 patients reported in literature.
CLINICAL CHARACTERISTICS
12/8/20
Badal S, Bajgain KT, Badal S, et al. | J Clin Virol
Aim: To conduct a comprehensive meta-analysis and systematic review to collect and analyze current evidence about COVID-19 in the pediatric population.
CLINICAL CHARACTERISTICS
12/8/20
Wilkinson R, Hines L, Holland A, et al.  | Harm Reduct J
Aim: To explore what harm reduction interventions and messaging are most effective during a pandemic-type situation.
UPDATED
12/7/20
Puyat J, Ahmad H, Avina-Galindo AM, et al | PLoS One
Aim: To review the evidence on home-based activities that have potential beneficial effects on mental health.
UPDATED
12/7/20
Hessami A, Shamshirian A, Heydari K, et al. | Am J Emerg Med
Aim: To study cardiovascular disease burden among COVID-19 patients.
UPDATED
12/7/20
Rodriguez-Gonzalez M, Castellano-Martinez-A, Cascales-Poyatos HM, et al. | World J Clin Cases
Aim: To summarize the current knowledge about the potential cardiovascular involvement in pediatric COVID-19 in order to give a perspective on how to take care of them during the current pandemic emergency.
12/7/20
Kim JS, Lee KH, Kim GE, et al. | Eur Rev Med Pharmacol Sci
Aim: To analyze clinical characteristics and mortality of patients with hematologic malignancies and COVID-19.
12/7/20
Vakhshoori M, Emami SA, Heidarpour M, et al. | Iran J Kidney Dis
Aim: To define the frequency of AKI as well as two specific renal biomarkers including BUN and serum Cr among individuals suffering from COVID-19 infection. 
12/7/20
Hu BS, Hu MZ, Jiang LX, et al. | Eur Rev Med Pharmacol Sci
Aim: To review the evidence on the use of ECMO in patients with COVID-19.
12/7/20
Ampuero J, Sanchez-Torrijos Y, Del Rosario Garcia Lozano M, et al. | Rev Esp Enferm Dig
Aim: To assess the impact of the baseline liver function (AST, ALT, and bilirubin) on COVID-19-related outcomes, including on mortality, intensive care unit admission, and non-fatal severe complications.
12/7/20
Bandyopadhyay S, Baticulon RE, Kadhum M, et al. | BMJ Glob Health
Aim: To estimate COVID-19 infections and deaths in healthcare workers (HCWs) from a global perspective during the early phases of the pandemic.
12/7/20
Berardicurti O, Ruscitti P, Ursini F, et al. | Clin Exp Rheumatol
Aim: To review the evidence on the mortality rate in TCZ-treated patients with COVID-19.
12/7/20
Chu Y, Yang J, Shi J, et al. | Eur J Med Res
Aim: To investigate the association between obesity and poor outcomes in patients with COVID-19 pneumonia.
12/7/20
 | NSW Health COVID-19 Critical Intelligence Unit
12/7/20
Jefferson T, Spencer EA, Brassey J, et al. | Clin Infect Dis
Aim: To review the evidence from studies relating SARS-CoV-2 culture with the results of reverse transcriptase polymerase chain reaction (RT-PCR) and other variables which may influence the interpretation of the test, such as time from symptom onset.
UPDATED
12/4/20
Shuto H, Komiya K, Yamasue M, et al. | Sci Rep
Aim: To review the evidence on the associations between corticosteroid treatment and any type of mortality and/or other clinical outcomes among noncritically ill patients with COVID-19.
12/4/20
Zarifkar P, Kamath A, Robinson C, et al. | Clin Oncol
Aim: To review the current evidence base pertaining to the prevalence, presentation and outcome of COVID-19 in cancer patients, in order to inform policy and practice going forwards.
UPDATED
12/4/20
Mohamed K, Yazdanpanah N, Saghazadeh A, et al. | Bioorg Chem
Aim: To provide an overview of studies that have used computational methods for drug repurposing in COVID-19.
12/4/20
da Silva FAF, de Brito BB, Santos MLC, et al. | Rev Soc Bras Med Trop
Aim: To review the evidence on GI symptoms associated with coronavirus disease 2019 (COVID-19) as well as of the serum levels of biomarkers related to liver function and lesion in SARS-CoV-2-infected individuals.
12/4/20
Alhumaid S, Al Mutair A, Al Alawi Z, et al. | Trop Med Infect Dis
Aim: To assess the efficacy and safety of lopinavir/ritonavir in COVID-19 patients in the extant published research.
UPDATED
12/4/20
Pollock A, Campbell P, Cheyne J, et al. | Cochrane Database Syst Rev
Aim: To review the evidence on the effects of interventions aimed at supporting the resilience and mental health of frontline health and social care professionals during and after a disease outbreak, epidemic or pandemic.
12/4/20
Komolafe TE, Agbo J, Olaniyi EO, et al. | Diagnostics
Aim: To perform a meta-analysis to evaluate the diagnostic performance of chest CT, common CT morphological abnormalities, disease prevalence, biodata information, and gender prevalence of patients.
UPDATED
12/4/20
Zuercher SJ, Kerksieck P, Adamus C, et al. | Front Public Health
Aim: To review the evidence on MHP prevalence rates published since 2000, during and after epidemics, including the general public, health care workers, and survivors.
UPDATED
12/4/20
National Collaborating Centre for Methods and Tools | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the effect of the COVID-19 pandemic on the use and cessation of tobacco and vaping products.
12/4/20
Lieneck C, Garvey J, Collins C, et al. | Healthcare
Aim: To evaluate the literature specific to rapid telehealth implementation during the current COVID-19 pandemic.
12/4/20
Lo Moro G, Sinigaglia T, Bert F, et al. | Int J Environ Res Public Health
Aim: To describe the main measures planned for the 2020–2021 academic year within the WHO European Region.
12/4/20
Torres-Castro R, Vasconcello-Castillo L, Alsina-Restoy X, et al. | Pulmonology
Aim: To determine the prevalence of restrictive pattern, obstructive pattern and altered diffusion in patients post-COVID-19 infection and to describe the different evaluations of respiratory function used with these patients.
UPDATED
12/4/20
Yifan C, Jun P | Front Endocrinol
Aim: To assess the clinical characteristics of elder patients with COVID-19.
12/4/20
Foldi M, Farkas N, Kiss S, et al. | Obesity
Aim: To evaluate the association between the distributions of CT?quantified fat mass and critical condition of patients with COVID?19.
12/3/20
Oakman J, Kinsman N, Stuckey R, et al. | BMC Public Health
Aim: To review the impact of WAH on individual workers’ mental and physical health, and determine any gender difference, to develop recommendations for employers and employees to optimise workers’ health.
12/3/20
Jain N, Varman R, Tarbox JA, et al. | Auris Nasus Larynx
Aim: To review the current knowledge of biomolecular factors surrounding otorhinolaryngeal illnesses and analyze their presence in COVID-19 virulence. 
12/3/20
Szarpak L, Adam I, Dzieciatkowski T, et al. | Postepy Nauk Medycznych
Aim: To identify the most frequently observed symptoms in pediatric patients with confirmed COVID-19.
12/3/20
Chi J, Gong W, Gao Q | Arch Gynecol Obstet
Aim: To summarize the clinical features and maternal–infant outcomes of 230 pregnant women (154 patients gave birth) infected with COVID-19 and their 156 infants, including the possibility and evidence of vertical transmission.
12/3/20
Zhou S, Xu J, Xue C, et al. | Ren Fail
Aim: To review the evidence on kidney-related outcomes of three recent pandemics: SARS, MERS, and COVID-19, which were associated with potentially fatal acute respiratory distress syndrome (ARDS).
UPDATED
12/3/20
Cai XJ, Tay JCK, Kui SL, et al. | Singapore Med J
Aim: To study in-hospital mortality in COVID-19 patients who were on ACEI/ARB as compared to those not on ACEI/ARB.
12/3/20
do Amaral WN, de Moraes CL, Dos Santos Rodrigues AP, et al. | Healthcare
Aim: To investigate pregnant women infected with COVID-19 in terms of signs and symptoms, type of delivery, comorbidities, maternal and neonatal outcomes, and the possibility of vertical transmission.
12/3/20
Aburas W, Alshammari TM | Saudi Pharm J
Aim: To provide an overview of pharmacists’ roles in disasters and formulating a definition of expected roles and tasks through which they can perform these roles properly.
12/3/20
Mahdi SS, Ahmed Z, Allana R, et al. | Medicina
Aim: To identify additional infection control measures implemented in dental practice globally to prevent cross-infection and evaluate the psychological impacts of the pandemic among dental professionals.
12/2/20
Fraiman P, Godeiro C, Moro E, et al. | Front Neurol
Aim: To review the evidence on the cerebrovascular events in COVID-19 infection.
12/2/20
Gunn H, McCormack S | CADTH
12/2/20
Das RR, Behera B, Mishra B, et al. | Indian J Med Microbiol
Aim: To review the effect of chloroquine and hydroxychloroquine on COVID-19 virological outcomes.
CANDIDATE THERAPEUTICS
12/2/20
Loomba RS, Aggarwal G, Villarreal EG, et al. | Blood Coagul Fibrinolysis
Aim: To compare laboratory results in COVID-19 patients with and without DVT with the aim of identifying risk factors for DVT in this population.
CLINICAL CHARACTERISTICS
12/2/20
Zhou L, Wang J, Xie R, et al. | J Altern Complement Med
Aim: To assess the effects of TCM as an auxiliary treatment for COVID-19 through a systematic review of randomized-controlled trials (RCTs).
UPDATED
12/2/20
Malas MB, Naazie IN, Elsayed N, et al. | EClinicalMedicine
Aim: To estimate the overall rates of TE of COVID-19 and further determine the association of TE with mortality among patients with COVID-19.
12/1/20
Shimabukuro PMS, Duarte ML, Imoto AM, et al. | Sao Paulo Med J
Aim: To identify, systematically evaluate and summarize the best available scientific evidence on environmental cleaning to prevent COVID-19 infection.
INFECTION CONTROL
12/1/20
Chou R, Dana T, Buckley D, et al. | Ann Intern Med
Aim: To examine the burden of SARS-CoV-2, SARS-CoV-1, and Middle Eastern respiratory syndrome (MERS)-CoV on HCWs and risk factors for infection, using rapid and living review methods.
UPDATED
WHO COLLABORATIVE
12/1/20
Yang J, Tian C, Chen Y, et al. | J Med Virol
Aim: To evaluate the impact of obesity on the onset, exacerbation, and mortality of coronavirus disease 2019 (COVID?19); and compare the effects of different degrees of obesity. 
UPDATED
CLINICAL CHARACTERISTICS
12/1/20
Schunemann HJ, Khabsa J, Solo K, et al. | Ann Intern Med
Aim: To review multiple streams of evidence regarding the benefits and harms of ventilation techniques for coronavirus infections, including that causing COVID-19.
UPDATED
11/30/20
Graber K, Byrne E, Goodacre E, et al. | Child Care Health Dev
Aim: To review of the impact of quarantine, isolation, or other restrictive environments on children’s play and whether play may mitigate the adverse effects of such restrictions.
UPDATED
11/30/20
da Rosa Mesquita R, Silva LCF, Santana FMS, et al. | Wien Klin Wochenschr
Aim: To systematize the literature regarding clinical manifestations of patients with confirmed COVID-19.
11/30/20
Wang Z, Deng H, Ou C, et al. | Medicine
Aim: To compare the differences in the field of demographic, comorbidities, clinical symptoms, complications and outcomes between severe and non-severe COVID-19.
11/30/20
Raja MA, Mendoza MA, Villavicencio A, et al. | Transplant Rev
Aim: To help expand our current limited knowledge base regarding COVID-19 in SOT recipients, especially looking at clinical presentations, treatment modalities and outcomes.
11/30/20
Meher BR, Padhy BM, Das S, et al. | J Assoc Physicians India
Aim: To evaluate the currently available data to provide evidence about CPT in COVD-19 patients. 
11/30/20
Amiri-Dashatan N, Koushki M, Ghorbani F, et al. | Gastroenterol Hepatol Bed Bench
Aim: To determine whether patients with elevated CRP, TNF?, and IL-6 levels may be at increased risk for severe infection and liver damage of COVID-19.
11/30/20
Makvandi S, Ashtari S, Vahedian-Azimi A | Gastroenterol Hepatol Bed Bench
Aim: To evaluate the symptoms of COVID-19 in pregnant women with a focus on gastrointestinal symptoms.
11/30/20
Bell V, Wade D | Soc Psychiatr Epidemiol
Aim: To estimate the additional burden of working directly with infected patients during epidemic and pandemic health emergencies.
UPDATED
11/30/20
Hannum ME, Ramirez VA, Lipson SJ, et al. | Chem Senses
Aim: To provide a comprehensive assessment of methodologies currently employed to quantify smell loss in COVID-19–positive patients and examine whether method type affects reported prevalence of smell loss in COVID-19 patients.
UPDATED
11/30/20
Mousquer GT, Peres A, Fiegenbaum M | Tuberculosis
Aim: To conduct a systematic review on the current literature on TB/COVID-19 co-infection cohorts, evaluating clinical and epidemiological data, focusing on its implications to the immune system.
11/30/20
Bekele F, Sheleme T, Fekadu G, et al. | SAGE Open Med
Aim: To summarize the knowledge, attitudes, and practice of COVID-19 among the general population and health workers across the globe.
11/30/20
Afra HS, Amiri-Dashatan N, Ghorbani F, et al. | Gastroenterol Hepatol Bed Bench
Aim: To report a pooled analysis of the association of the circulating levels of liver enzymes and total bilirubin with severe and non-severe COVID-19.
11/30/20
Bareeqa SB, Ahmed SI, Samar SS, et al. | Int J Psychiatry Med
Aim: To quantify COVID-19 mental health issues and its prevalence in China during the early period of the COVID-19 crisis.
UPDATED
11/30/20
Thrinuavukkarasu S, Kapoor N, Tina Cao, et al. | Diabetes Obes Metab
Aim: To examine the proportion of newly diagnosed diabetes in COVID-19 patients.
11/30/20
Azam M, Sulistiana R, Ratnawati M, et al. | Sci Rep
Aim: To estimate the incidence of recurrent SARS-CoV-2 RNA positivity after recovery from COVID-19 and to determine the factors associated with recurrent positivity. 
UPDATED
11/30/20
Maraolo AE, Grosi A | Immun Inflamm Dis
Aim: To gauge the safety profile of HCQ/CQ in the context of COVID?19 pandemic on the basis of data from RCTs published so far, to highlight the trade?off between pros and cons of HCQ/CQ repurposing to treat or prevent SARS?CoV?2 infection.
11/30/20
Jammu A, Chasen M, Lofters A, et al. | Support Care Cancer
Aim: To synthesise the available knowledge regarding the impact of the COVID-19 pandemic.
UPDATED
11/30/20
Cardwell K, Jordan K, Byrne P, et al. | Rev Med Virol
Aim: To summarise the evidence on non?contact thermal screening as a method through which to identify cases and reduce the spread of coronavirus disease (Covid?19).
11/30/20
Allan SM, Bealey R, Birch J, et al. | Eur J Psychotraumatol
Aim: To estimate the prevalence of common mental health disorders in HCWs based in hospitals where pandemic-affected patients were treated.
UPDATED
11/30/20
Islam N, Salameh JP, Leeflang MMG, et al. | Cochrane Database Syst Rev
Aim: To determine the diagnostic accuracy of chest imaging (computed tomography (CT), X?ray and ultrasound) in people with suspected or confirmed COVID?19.
UPDATED
DIAGNOSTICS
11/29/20
Anthony Jr, B | Inform Health Soc Care
Aim: To discuss the strategic role of telehealth and digital care in managing the COVID-19 pandemic among medical-care systems globally.
INFECTION CONTROL
11/28/20
Pasin L, Navalesi P, Zangrillo A, et al. | J Cardiothorac Vasc Anesth
Aim: To evaluate the effect of corticosteroid therapy in patients with COVID-19 at different severity levels.
CANDIDATE THERAPEUTICS
11/27/20
Arruda AG, Beyene TJ, Kieffer J, et al. | Animals
Aim: To summarize the available literature on swine depopulation methods and to highlight critical gaps in knowledge.
11/27/20
Wang Z, Deng H, Ou C, et al. | Medicine (Baltimore)
Aim: To compare the differences in the field of demographic, comorbidities, clinical symptoms, complications and outcomes between severe and non-severe COVID-19. To conclude the potential risk factors to severe COVID-19 patients.
UPDATED
11/27/20
Zhang X, Yang X, Jiao H, et al. | Aging
Aim: To investigate the role of coagulation dysfunction in the severity of COVID-19 progression.
CLINICAL CHARACTERISTICS
11/27/20
Asadi-Pooya AA, Simani L, Shahisavandi M, et al. | Neurol Sci
Aim: To discuss the evidence on the occurrence of de novo seizures in patients with COVID-19, the consequences of this catastrophic disease in people with epilepsy (PWE), and the electroencephalographic (EEG) findings in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/27/20
Griffin J, Casey M, Collins Á, et al. | BMJ Open
Aim: To conduct a review of available evidence to advise on appropriate parameter values for serial interval and generation time in national COVID-19 transmission models for Ireland and on methodological issues relating to those parameters.
UPDATED
11/27/20
Rostami A, Sepidarkish M, Leeflang MMG, et al. | Clin Microbiol Infect
Aim: To estimate the global and regional seroprevalence rates in humans of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and to assess whether seroprevalence is associated with geographical, climatic and/or sociodemographic factors.
CLINICAL CHARACTERISTICS
11/27/20
Kuek JTY, Ngiam LXL, Kamal NHA, et al. | Philos Ethics Humanit Med
Aim: To evaluate prevailing accounts of physicians facing dying patients in ICUs through the lens of Personhood.
MENTAL HEALTH
11/27/20
Amicucci M, Mastronuzzi A, Ciaralli I, et al. | J Clin Med
Aim: To collect and analyze scientific literature regarding the management, interventions, and strategies to prevent the spread of COVID-19 in children with cancer.
INFECTION CONTROL
11/27/20
Dar-Odeh N, Elsayed S, Babkair H, et al. | J Dent Sci
Aim: To highlight COVID-19 pharmacotherapeutic agents that are relevant to dental practice in terms of their clinical indications in COVID-19 and dental practice, as well as their adverse effects as they impact the dental patient.
CANDIDATE THERAPEUTICS
11/26/20
Lombardi A, Asahi AM, Gupta A, et al.  | Radiol Med
Aim: To review the most common extra-pulmonary manifestations of SARS, Influenza, MERS, and COVID-19.
CLINICAL CHARACTERISTICS
11/25/20
Vakhshoori M, Heidarpour M, Shafie D, et al. | Arch Iran Med
Aim: To analyze the available COVID-19 data on acute cardiac injury, using troponin and brain natriuretic peptide (BNP) levels.
CLINICAL CHARACTERISTICS
11/25/20
Yang X, Tian S, Guo H | Int Immunopharmacol
Aim: To gain clarity regarding AKI incidence and renal replacement therapy (RRT) use in COVID-19 patients.
CLINICAL CHARACTERISTICS
11/25/20
Karabay M, Ç?nar N, Karakaya Suzan Ö, et al. | J Matern Fetal Neonatal Med
Aim: To investigate the available evidence describing neonatal outcomes in newborns who have SARS-CoV-2 infection in order to guide prevention of COVID-19 in newborns.
UPDATED
INFECTION CONTROL
11/25/20
Chu C, Zeng S, Hasan AA, et al. | Br J Clin Pharmacol
Aim: To review the evidence on the effect of RAAS blockers on the expression of ACE2 and the risk of SARS-Cov-2 infection.
CLINICAL CHARACTERISTICS
11/25/20
Sameni F, Hajikhani B, Yaslianifard S, et al. | Front Med
Aim: To provide a systematic review and meta-analysis of various skin manifestations among patients with COVID-19 through case reports/case series and prevalence studies.
CLINICAL CHARACTERISTICS
11/25/20
Jindal R, Chauhan P | J Family Med Prim Care
Aim: To describe the cutaneous manifestations of COVID-19 patients from diverse regions with the aim of highlighting any important associations.
CLINICAL CHARACTERISTICS
11/25/20
Garg M, Gupta P, Maralakunte M, et al. | Clin Imaging
Aim: To evaluate pooled prevalence, sensitivity, and specificity of chest computed tomography (CT) and radiographic findings for novel coronavirus-2019 (COVID-19) pneumonia.
DIAGNOSTICS
11/25/20
Kiss S, Gede N, Hegyi P, et al. | Med Microbiol Immunol
Aim: To review the evidence on the correlation between early changes in the laboratory parameters and the clinical outcomes of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Wang KC, Xiao R, Cheung ZB, et al. | J Orthop
Aim: To assess the risk of early mortality in hip fracture patients with COVID-19 infection who undergo surgical intervention.
CLINICAL CHARACTERISTICS
11/25/20
Li B, Zhang S, Zhang R, et al. | Front Pediatr
Aim: To evaluate the epidemiological spectrum and clinical characteristics of children infected with SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Paul D, Gupta A, Maurya AK | PLoS One
Aim: To evaluate research done, prior to COVID-19 pandemic, on various decontamination methods for reprocessing of N95-FFRs.
UPDATED
INFECTION CONTROL
11/25/20
Nearchou F, Flinn C, Hennessy E, et al  | Int J Environ Res Public Health
Aim: To provide a systematic review of the evidence on the COVID-19 pandemic's impact on youth mental health.
UPDATED
MENTAL HEALTH
11/25/20
Lee Y, Kirubarajan A, Patro N, et al. | Am J Surg
Aim: To assess all research literature related to changes in surgical practice during disease outbreaks and epidemics, especially during the current COVID-19 pandemic.
INFECTION CONTROL
11/25/20
Jiménez D, García-Sanchez A, Rali P, et al. | Chest
Aim: To review the evidence on the incidence of VTE and bleeding among hospitalized patients with COVID-19?
UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Saniasiaya J, Islam MA, Abdullah B | Laryngoscope
Aim: To estimate the overall pooled prevalence of olfactory dysfunction in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Singh AK, Jena A, Kumar-M P, et al. | United European Gastroenterol J
Aim: To review the evidence on the risk of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection and clinical outcomes of coronavirus disease (COVID-19) in inflammatory bowel disease.
CLINICAL CHARACTERISTICS
11/25/20
Galanis P, Vraka I, Fragkou D, et al. | J Hosp Infect
Aim: To determine the seroprevalence of SARS-CoV-2 antibodies among HCWs, and to find out the factors that are associated with this seroprevalence.
UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Katsanos AH, Palaiodimou L, Zand R, et al. | Ann Neurol
Aim: To evaluate the potential impact of coronavirus disease (COVID-19) on the management and outcomes of acute stroke.
CLINICAL CHARACTERISTICS
11/24/20
Chang PC, Yang CC, Kao KC, et al  | Aging
Aim: To compare clinical outcomes in patients hospitalized for COVID-19 with those of patients hospitalized for SARS.
CLINICAL CHARACTERISTICS
11/24/20
Zhang G, Wu Y, Xu R, et al. | J Med Virol
Aim: To explore whether the use of RAAS inhibitors was associated with severe disease and mortality in COVID?19 patients.
CANDIDATE THERAPEUTICS
11/24/20
France R, Vseteckova J, Lapwood S, et wood | Oxford COVID-19 Evidence Service
11/24/20
Novoa RH, Quintana W, Llancarí P, et al. | Travel Med Infect Dis
Aim: To review all cases from the current literature and provide up-to-date scientific evidence on the clinical characteristics, maternal outcomes, perinatal outcomes and the possibility of vertical transmission in the infected pregnant women.
UPDATED
CLINICAL CHARACTERISTICS
11/24/20
Perveen RA, Nasir M, Talha KA, et al. | Med J Malaysia
Aim: To evaluate the effectiveness of antiviral therapies in the treatment of COVID-19.
CANDIDATE THERAPEUTICS
11/23/20
Bedrosian N, Mitchell E, Rohm E, et al. | Environ Sci Technol
Aim: To review the evidence on hygiene intervention effectiveness against SARS-CoV-2.
INFECTION CONTROL
11/23/20
Zhang J, Wang H, Wei M, et al.  | Aging
Aim: To assess the incidence of cerebrovascular disease as a comorbidity in COVID-19 patients.
CLINICAL CHARACTERISTICS
11/20/20
Ji P, Zhu J, Zhong Z, et al. | Medicine
Aim: To review the evidence on the potential association between inflammatory markers and severe COVID-19.
CLINICAL CHARACTERISTICS
11/20/20
Takla M, Jeevaratnam K | Saudi Pharm J
Aim: To systematically identify and collate 24 studies describing the use of CQ and HCQ in human clinical trials and to provide a detailed synthesis of evidence of its efficacy and safety.
CANDIDATE THERAPEUTICS
11/20/20
Turkistani K & Turkistani K | J Int Soc Prev Community Dent
Aim: To provide dentists and dental auxiliary with insights regarding risk and precautions during COVID-19 crisis.
INFECTION CONTROL
11/20/20
Abdo C, Miranda EP, Santos CS, et al. | Indian J Psychiatry
Aim: To perform a systematic review of the literature regarding the consequences of severe acute respiratory syndrome-CoV-2 infection in terms of domestic violence and substance abuse, and compare incidences found.
MENTAL HEALTH
11/20/20
Rezapour A, Souresafil A, Peighambari MM, et al.  | Int J Surg
Aim: To summarize economic evaluation evidence of preventing strategies, programs, and treatments of COVID-19.
11/20/20
Park S, Lee Y, Michelow IC, et al. | Open Forum Infect Dis
Aim: To systematically address the global seasonal patterns of human coronavirus (HCoV) infections.
INFECTION CONTROL
11/20/20
Bin Arif T, Khalid S, Siddiqui MS, et al. | Hong Kong Med J
Aim: To provide insight into the incidence, patterns, risk factors, histopathological findings, and relationship with disease severity of COVID-19-associated liver injury.
CLINICAL CHARACTERISTICS
11/20/20
Robertson LJ, Maposa I, Somaroo H, et al. | S Afr Med J
Aim: To understand which mental health conditions may occur in healthcare workers and which interventions could be considered during the COVID-19 pandemic.
MENTAL HEALTH
11/20/20
Liu D, Baumeister RF, Zhou Y | J of Psychiatric Res
Aim: To examine how the mental status of SARS survivors changed after infection and after hospital release.
MENTAL HEALTH
11/20/20
Nunes JPL | Porto Biomed J
Aim: To perform a systematic review on mortality associated to the use of ACEi in patients with COVID-19 disease.
CANDIDATE THERAPEUTICS
11/20/20
Vijenthira A, Gong IY, Fox TA, et al. | Blood
Aim: To perform a systematic review and meta-analysis to estimate the risk of death and other important outcomes for patients with hematologic malignancy infected with COVID-19 .
CLINICAL CHARACTERISTICS
11/20/20
Bwire GM, Njiro BJ, Mwakawanga DL, et al. | Med Virol
Aim: To determine the likelihood of vertical transmission among COVID?19 exposed infants and determine whether antibodies against SARS?CoV?2 were generated among COVID?19 vertically exposed but negative infants.
INFECTION CONTROL
11/20/20
Wang C, Zhang H, Zhou M, et al. | Eur Rev Med Pharmacol Sci
Aim: To explore the relationship between the prognosis of COVID-19 patients and thromboembolic events.
CLINICAL CHARACTERISTICS
11/20/20
Gómez-Durán EL, Martin-Fumadó C, Forero CG.  | Occup Environ Med
Aim: To summarise the research evidence on the psychological impact of quarantine on healthcare workers.
MENTAL HEALTH
11/20/20
Faraone I, Labanca F, Ponticelli M, et al. | Molecules
Aim: To analyze preclinical and clinical studies on HCQ potential use in viral infection and chronic diseases.
CANDIDATE THERAPEUTICS
11/20/20
Younes S, Younes N, Shurrab F, et al. | Rev Med Virol
Aim: To compile and discuss all articles that describe experimental or natural infections with SARS-CoV-2.
INFECTION CONTROL
11/20/20
Tsankov BK, Allaire JM, Irvine MA, et al  | Int J Infect Dis
Aim: To investigate the effects of pediatric comorbidities on COVID-19 severity. 
CLINICAL CHARACTERISTICS
11/20/20
Dorantes-Acosta E, Ávila-Montiel D, Klünder-Klünder M, et al. | Bol Med Hosp Infant Mex
Aim: To analyze the available data associated with COVID-19 infection and mortality in pediatric cancer patients and to provide useful information to plan and design strategies in this group.
CLINICAL CHARACTERISTICS
11/20/20
Zreiq R, Haouas N, Khemakhem AM, et al. | J of Pharmaceutical Res
Aim: To review the "state-of-the-art" of treatment modalities and propose a practical therapeutic algorithm for the COVID-19 management.
CANDIDATE THERAPEUTICS
11/20/20
Zhao M, Lu J, Tang Y, et al. | Eur J Clin Pharmacol
Aim: To explore the effectiveness and safety of tocilizumab recently used for treating COVID-19.
CANDIDATE THERAPEUTICS
11/20/20
Sánchez OR, Vale DB, Rodrigues L, et al. | Int J Gynaecol Obstet
Aim: To analyze the existing scientific literature on strategies and recommendations to respond to VAW during the implementation of social distancing measures in response to the COVID-19 pandemic.
MENTAL HEALTH
11/20/20
National Collaborating Centre for Methods and Tools | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the risk of COVID-19 transmission across different indoor settings in the community.
INFECTION CONTROL
11/19/20
Mair M, Singhavi H, Pai A, et al. | Laryngoscope
Aim: To examine the pooled prevalence of symptoms, laboratory tests, and imaging of all COVID-19 infected patients.
11/19/20
Haque A, Minhaj A, Ahmed A, et al. | AIMS Medical Science
Aim: To analyze the prevalence of thromboembolic events in the hospitalized COVID-19 patients.
CLINICAL CHARACTERISTICS
11/19/20
Alves GS, Casali ME, Veras AB, et al. | Front Psychiatry
Aim: To discuss psychoeducation measures and brief psychosocial interventions designed in a home setting.
MENTAL HEALTH
11/19/20
Kashour T, Abdulhak AAB, Tlayjeh H, et al. | Am J Ther
Aim: To review the evidence on the association between prior use of ACEIs and ARBs and mortality due to COVID-19 disease.
CLINICAL CHARACTERISTICS
11/19/20
Ouyang L, Gong Y, Zhu Y, et al. | Am J Emerg Med
Aim: To explore the relationship of acute kidney injury (AKI) with the severity and mortality of coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
11/19/20
Kubjane M, McCreedy N, Cariou B, et al. | Endocrinol Metab
Aim: To investigate the association between diabetes and COVID-19 disease severity in patients hospitalized due to COVID-19.
CLINICAL CHARACTERISTICS
11/19/20
Cheruiyot I, Kipkorir V, Ngure B, et al. | Am J Emerg Med
Aim: To evaluate whether malignancies are associated with a significantly enhanced odds of COVID-19 severity and mortality.
CLINICAL CHARACTERISTICS
11/19/20
Lim ZJ, Subramaniam A, Reddy MP, et al. | Am J Respir Crit Care Med
Aim: To examine the case fatality rate of patients with COVID-19 receiving invasive medical ventilation.
CANDIDATE THERAPEUTICS
11/19/20
Udomsinprasert W, Jittikoon J, Sangroongruangsri S, et al. | J Clin Immunol
Aim: To determine associations of circulating levels of inflammatory cytokines with severity and mortality of COVID-19 by systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
11/19/20
Sze S, Pan D, Nevill CR, et al. | EClinicalMedicine
Aim: To determine whether the risk of SARS-CoV-2 infection, COVID-19 intensive care unit (ICU) admission and mortality are associated with ethnicity. 
UPDATED
CLINICAL CHARACTERISTICS
11/19/20
Meng M, Zhao Q, Kumar R, et al. | Aging
Aim: To review the evidence on the effects of coronary heart disease (CHD), hypertension and diabetes on the development of severe COVID-19. 
CLINICAL CHARACTERISTICS
11/19/20
Beaudry G, Zhong S, Whiting D, et al. | BMJ Glob Health
Aim: To synthesise the evidence on outbreaks of highly contagious diseases in prison.
UPDATED
INFECTION CONTROL
11/19/20
Liaw J, Saadi R, Patel VA, et al. | Otol Neurotol
Aim: To systematically review the available medical literature to investigate the viral load in the middle ear and mastoid cavity and the potential risk of exposure to airborne viruses during otologic surgery.
INFECTION CONTROL
11/19/20
Yang J, Tian C, Chen Y, et al. | J Med Virol
Aim: To explore the relationship between obesity and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
11/19/20
Li X, Liu C, Mao Z, et al. | Crit Care
Aim: To evaluate the predictive values of NLR on disease severity and mortality in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
11/19/20
Stegeman I, Ochodo EA, Guleid F, et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of routine laboratory testing as a triage test to determine if a person has COVID?19.
UPDATED
DIAGNOSTICS
11/19/20
da Silva RCM, Marinho LCN, de Araujo Silva DN, et al. | Travel Med Infect Dis
Aim: To conduct an integrative literature review reporting saliva use as a sample for the SARS-CoV-2 diagnosis.
DIAGNOSTICS
11/19/20
Mehraeen E, Salehi MA, Behnezhad F, et al. | Infect Disord Drug Targets
Aim: To review the current evidence of COVID-19 transmission modes.
INFECTION CONTROL
11/19/20
Wu T, Zou Z, Yang D, et al. | Age Aging
Aim: To explore the factors associated with prevalence of venous thromboembolism (VTE) in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
11/18/20
Galli F, Pozzi G, Ruggiero F, et al. | Front Psychiatry
Aim: To provide evidence of the psychopathologic burden on health care workers (HCWs) of the first two deadly coronavirus outbreaks to get lessons for managing the current burden of COVID-19 outbreak.
MENTAL HEALTH
11/18/20
Serafim RB, Póvoa P, Souza-Dantas V, et al. | Clin Microbiol Infect
Aim: To describe the clinical course and outcomes of COVID-19 pneumonia in critically ill patients.
UPDATED
11/18/20
Abdulla S, Hussain A, Azim D, et al. | Cureus
Aim: To draw generalized conclusions regarding impaired liver biochemistry and its potential relationship with COVID-19 disease severity.
CLINICAL CHARACTERISTICS
11/18/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence for transmission of COVID-19 in different settings, and to determine which settings are high risk.
11/18/20
Bansal A, Kumar A, Patel D, et al. | Am J Cardiol
Aim: To evaluate the association between cardiac injury and all-cause mortality, intensive care unit (ICU) admission, mechanical ventilation, acute respiratory distress syndrome, acute kidney injury and coagulopathy.
CLINICAL CHARACTERISTICS
11/18/20
Spencer N, Nathawad R, Arpin E, et al. | BMJ Paediatr Open
Aim: To review the evidence on the impact of pandemics on existing inequities in routine vaccination coverage.
11/18/20
Fischer R, Bortolini T, Karl JA, et al. | Front Psychol
Aim: To provide a broad summary of the current evidence drawn from published meta-analyses in order to evaluate the effectiveness of self-guided therapeutic practices which can be implemented by individuals on their own, including during physical distancing and quarantine measures.
MENTAL HEALTH
11/18/20
Koshy AN, Murphy AC, Farouque O, et al. | Intern Med J
Aim: To investigate whether RAS inhibitors increased the likelihood of a positive test or death/severe illness in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/18/20
Kaye A, Siegel R | PeerJ
Aim: To investigate and synthesize existing evidence for the efficacy of TCZ in reducing COVID-19 mortality.
UPDATED
CANDIDATE THERAPEUTICS
11/18/20
Ramos CCR, Roque JLA, Sarmiento DB, et al. | Int J Health Sci
Aim: To review the literature on the use of ultraviolet-C (UV-C) sterilization to assess its clinical efficacy in reducing risk and transmission of nosocomial infections as well as its associated health safety or hazards.
INFECTION CONTROL
11/17/20
Yonas E, Alwi I, Pranata R, et al. | Diabetes Metab Syndr
Aim: To comprehensively study the various levels of immunological parameters in patients with COVID 19.
CLINICAL CHARACTERISTICS
11/17/20
Hussein M, Toraih E, Elshazli R, et al. | Ann Surg
Aim: To systematically review and meta-analyze all literature reporting the basic reproductive number (R0), effective reproductive number (Re or Rt), and the serial interval (SI) values of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection.
INFECTION CONTROL
11/16/20
Yoon YK, Lee J, Kim SI, et al  | J Korean Med Sci
Aim: To derive suggestions for short-, mid-, and long-term strategies for medical resource management beyond the COVID-19 pandemic.
11/16/20
Raharja A, Tamara A, Kok LT | J Racial Ethn Health Disparities
Aim: To review the association between ethnicity and poor Covid-19 outcomes including all-cause mortality, hospitalisation, critical care admission, respiratory and kidney failure.
UPDATED
CLINICAL CHARACTERISTICS
11/16/20
Wong CKH, Wong JYH, Tang EHM, et al. | Sci Rep
Aim: To investigate the comorbidities, symptoms, clinical characteristics and treatment of COVID-19 patients. 
UPDATED
CLINICAL CHARACTERISTICS
11/16/20
Joseph B, Dibas M, Evanson KW, et al. | Expert Rev Anti Infect Ther
Aim: To systematically review the clinical literature reporting the use of Lopinavir/ritonavir (LPV/r) for the treatment of patients with COVID-19 to assess the efficacy of LPV/r for the treatment of Cornonavirus disease 19 (COVID-19).
CANDIDATE THERAPEUTICS
11/16/20
Yang Q, Yang X | PLoS One
Aim: To evaluate the association of kidney impairment with the development of COVID-19.
CLINICAL CHARACTERISTICS
11/16/20
Juhasz MF, Ocskay K, Kiss S, et al. | World J Gastroenterol
Aim: To assess all the available evidence in the literature relating to coronavirus disease 2019 (COVID-19) and AP.
UPDATED
CLINICAL CHARACTERISTICS
11/16/20
Akin H, Kurt R, Tufan F, et al. | Diseases
Aim: Too present the currently available data regarding the GI symptoms of COVID-19 patients, and to compare the frequency of GI symptoms in early stage (Eastern) mostly Chinese data to the current stage (Western) non-Chinese data. 
CLINICAL CHARACTERISTICS
11/16/20
Pant S, Perras C | CADTH
Aim: To describe the trial characteristics and estimated primary completion dates of the ongoing phase II, phase III, and phase IV studies evaluating drugs to prevent or treat COVID-19.
UPDATED
11/16/20
Bustos R, Jaramillo-Bustamante JC, Vasquez-Hoyos P, et al. | Pediatr Emerg Care
Aim: To review the evidence on pediatric inflammatory multisystem syndrome associated with SARS-CoV-2.
CLINICAL CHARACTERISTICS
11/16/20
Pinedo-Torres I, Flores-Fernandez M, Yovera-Aldana M, et al. | Clin Med Insights Endocrinol Diabetes
Aim: To determine the prevalence of diabetes comorbidity and its associated unfavorable health outcomes in patients with acute respiratory syndromes for coronavirus disease according to virus types.
UPDATED
CLINICAL CHARACTERISTICS
11/14/20
Zou H, Lu J, Liu J, et al. | Int J Infect Dis
Aim: To collect current evidence on pediatric PMIS and provide insights into pathogenesis, hopefully, providing possible clues for further research and treatment at this moment.
CLINICAL CHARACTERISTICS
11/13/20
Haiduc AA, Ogunjimi M, Shammus R, et al. | Cardiol Young
Aim: To examine the literature to determine if both paediatric and adult patients diagnosed with congenital heart disease (CHD) are at a higher risk of poor outcomes if they have the coronavirus disease 2019 (COVID-19), compared to those without CHD.
CLINICAL CHARACTERISTICS
11/13/20
Kubota T, Kuroda N | Clin Neurol Neurosurg
Aim: To evaluate the severity of COVID-19 and its effect on neurological symptoms in patients with preexisting neurological disorder and COVID-19.
CLINICAL CHARACTERISTICS
11/13/20
Bellos I, Pandita A, Panza R | Eur J Obstet Gynecol Reprod Biol
Aim: To evaluate maternal and neonatal outcomes in covid-19 pregnancies and identify factors associated with perinatal viral transmission.
CLINICAL CHARACTERISTICS
11/13/20
Lin L, Wang X, Ren J, et al. | BMJ Open
Aim: To analyse the incidence, risk factors and impact of acute kidney injury (AKI) on the prognosis of patients with COVID-19.
CLINICAL CHARACTERISTICS
11/13/20
Li H, Hu Y, Tang H, et al. | Am J Chin Med
Aim: To systematically review evidence on the efficacy and safety of glycyrrhizin preparations for SARS and MERS for application to COVID-19.
CANDIDATE THERAPEUTICS
11/12/20
Bellini D, Panvini N, Carbone I, et al. | J Comput Assist Tomogr
Aim: To perform a meta-analysis assessing the diagnostic yield of computed tomography (CT) for the identification of coronavirus disease 2019 (COVID-19) using repeated reverse transcriptase polymerase chain reaction testing or confirmed true-negative state as reference standard.
DIAGNOSTICS
11/12/20
Wang K, Wu C, Xu J, et al. | EClinicalMedicine
Aim: To describe the clinical outcomes of operative patients with COVID-19, and the safety of medical staff during the perioperative period to take appropriate protective measures to avoid cross-infection.
11/12/20
Fredericks S, Miranda J, Sidani S, et al. | Brain Behav Immun Health
Aim: To inform evidence-based decision-making pertaining to the selection of effective strategies or therapies that this cohort could use to promote mental health and resilience both within the clinical practice and academic environment.
11/12/20
Hong TS, Gonzalez J, Nahass RG, et al. | Pharmacy
Aim: To evaluate the impact of HCQ exposure on mortality in hospitalized patients with COVID-19. 
11/12/20
Vardhelli V, Pandita A, Pillai A, et al. | Eur J Pediatr
Aim: To summarize available literature on the clinical spectrum of COVID-19 in neonates and mothers and suggest a practical approach towards management of clinical scenarios.
CLINICAL CHARACTERISTICS
11/12/20
Li P, Wang Y, Peppelenbosch MP, et al. | Int J Infect Dis
Aim: To comprehensively compare the clinical features of hospitalized COVID-19 patients with hospitalized 2009 influenza pandemic patients.
CLINICAL CHARACTERISTICS
11/11/20
Kuswardhani RAT, Henrina J, Pranata R, et al. | Diabetes Metab Syndr
Aim: To assess the association between CCI and a composite of poor outcomes in COVID-19 patients.
CLINICAL CHARACTERISTICS
11/11/20
Mahalingasivam V, Carik A, Tomlinson LA, et al. | Kidney Int Rep
Aim: To synthesise, analyse and appraise what has been learnt so far to help clinicians and policy makers better understand the risks to kidney transplant recipients, as well as identify gaps for future collaborative research for this global health challenge.
UPDATED
INFECTION CONTROL
11/11/20
Zuin M, Guasti P, Roncon L, et al. | Int J Geriatr Psychiatry
Aim: To evaluate the mortality risk in elderly patients with dementia and COVID?19 infection.
CLINICAL CHARACTERISTICS
11/11/20
Tleyjeh IM, Kashour Z, Damlaj M, et al. | Clin Microbiol Infect
Aim: To perform a living systematic review of the literature about the efficacy and toxicity of the IL-6 receptor antagonist, tocilizumab, in COVID-19 patients.
CANDIDATE THERAPEUTICS
11/11/20
Oscanoa TJ, Vidal X, Kanters JK, et al. | Int J Antimicrob Agents
Aim: To conduct a meta-analysis of the frequency of LQT in patients with SARS-CoV-2 infection treated with HCQ.
CANDIDATE THERAPEUTICS
11/11/20
Aziz M, Haghbin H, Lee-Smith W, et al. | Ann Gastroenterol
Aim: To review the evidence on the gastrointestinal predictors of severe COVID-19.
CLINICAL CHARACTERISTICS
11/11/20
Choi Y, Lee MK | Eur J Radiol
Aim: To comprehensively evaluate the incidences of abnormal neuroimaging findings in patients with COVID-19 via a systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
11/11/20
Hellou MM, Gorska A, Mazzaferri F, et al. | Clin Microbiol Infect
Aim: To evaluate the diagnostic test accuracy (DTA) of nucleic acid amplification tests (NAATs) for the diagnosis of coronavirus infections.
DIAGNOSTICS
11/11/20
Mudatsir M, Fajar JK, Wulandari L, et al. | F1000
Aim: To identify the predictors associated with poor clinical outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/11/20
Cachon-Zagalaz J, Sanchez-Zafra M, Sanabrias-Moreno D, et al. | Front Psychol
Aim: To learn about the research carried out on the child population in times of confinement, especially those dealing with the psychological and motor aspects of minors.
MENTAL HEALTH
11/11/20
Tleyjeh I, Kashour Z, Al Dosary O, et al. | Mayo Clin Proc Innov Qual Outcomes
Aim: To systematically review the literature and estimate the risk of cardiac toxicity in patients receiving CQ or HCQ for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/11/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on monitoring wastewater as a surveillance strategy for COVID-19.
11/9/20
Ren L, Xu W, Overton JL, et al. | Front Pharmacol
Aim: To examine the safety profiles of these medications, we systematically evaluated the adverse events (AEs) of these medications from published randomized controlled trials (RCTs).
UPDATED
CANDIDATE THERAPEUTICS
11/9/20
Alimohamadi Y, Sepandi M, Taghdir M, et al.  | J Prev Med Hyg
Aim: To estimate the prevalence of clinical symptoms of COVID-19 in a systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
11/9/20
Mekonnen D, Mengist HM, Derbi A, et al.  | Rev Med Virol
Aim: To assess the diagnostic test accuracy (DTA) of severe acute respiratory syndrome coronavirus 2 (SARS?COV?2) serological test methods and the kinetics of antibody positivity. 
DIAGNOSTICS
11/9/20
Ye L, Yang Z, Liu J, et al. | J Gastroenterol Hepatol
Aim: To highlight the gaps in our knowledge about the prevalence and clinical significance of GI symptoms in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/9/20
Jeevananthan C, Muhamed NA, Jafaar MH, et al. | BMJ Open
Aim: To identify the effects of temperature, humidity and air quality in the transmission of SARS-CoV-2 and to determine if the effects are linked to anthropic activities.
UPDATED
INFECTION CONTROL
11/9/20
Lebrasseur A, Fortin-Bedard N, Lettre J, et al.  | Disabil Health J
Aim: To review the impact of the COVID-19 pandemic, and associated isolation and protective measures, among people with physical disabilities.
UPDATED
MENTAL HEALTH
11/9/20
Yue J, Yan W, Sun Y, et al. | Psychol Med
Aim: To review the available data on the benefits of interventions to reduce adverse mental health sequelae of infectious disease outbreaks, and to offer guidance for mental health service responses to infectious disease pandemic.
MENTAL HEALTH
11/9/20
Aggarwal K, Agarwall A, Jaiswal N, et al.  | PLoS ONE
Aim: To evaluate the epidemiology and clinical features of ocular surface manifestations and complications related to COVID-19 infection, to assess the risk of transmission to patients and healthcare workers through ocular secretions and to determine whether ocular involvement has any correlation with the severity of respiratory symptoms and overall prognosis.
UPDATED
CLINICAL CHARACTERISTICS
11/9/20
Hasan I, Rashid T, Suliman S, et al. | Rom J Intern Med
Aim: To review the evidence on COVID-19 in kidney transplant recipients.
CLINICAL CHARACTERISTICS
11/9/20
Ssentongo A, Ssentongo P, Heilbrunn E, et al | Open Heart
Aim: To explore the association of RAAS inhibitors, including angiotensin-converting inhibitors (ACEi) and angiotensin II receptor blockers (ARBs) with COVID-19 mortality in patients with hypertension. 
UPDATED
CLINICAL CHARACTERISTICS
11/9/20
Kiss P, Carcel C, Hockham C, et al. | Eur Heart J Qual Care Clin Outcomes
Aim: To assess the extent to which health services related to the care and management of acute cardiovascular events have been impacted during the COVID-19 pandemic.
11/9/20
Matsushita K, Ding N, Kou M, et al. | Glob Heart
Aim: To explore pre-existing CVD and its traditional risk factors as risk factors of severe COVID-19 (defined as death, acute respiratory distress syndrome, mechanical ventilation, or intensive care unit admission). 
UPDATED
CLINICAL CHARACTERISTICS
11/9/20
Sridharan GK,  Vegunta R, Rokkam VRP, et al. | Am J Ther
Aim: To examine and appraise the incidence of VTE, major VTE, PE, and DVT in hospitalized COVID-19 patients by meta-analysis methods and, in particular, analyze whether the use of therapeutic anticoagulation decreased the odds of thromboembolic events compared with prophylactic anticoagulation.
CLINICAL CHARACTERISTICS
11/6/20
Santos M, Torres D, Cardoso PC, et al. | Braz Oral Res
Aim: To investigate the efficiency of cloth masks in reducing transmission and contamination by droplets and aerosols for the general population and healthcare workers.
11/6/20
Mallett S, Allen J, Graziadio S, et al. | BMC Med
Aim: To examine at what time points during SARS?CoV?2 infection it is detectable at different anatomical sites using RT?PCR based tests.  
UPDATED
11/6/20
Yadav R, Srivastava DK, Bajpai PK, et al. | J Neurosci Rural Pract
Aim: To determine the neurological involvement and its manifestations in COVID-19 patients.
11/6/20
Pereira M, Damascena AD, Azevedo LMG, et al. | Crit Rev Food Sci Nutr
Aim: To analyze the association between vitamin D deficiency and COVID-19 severity, via an analysis of the prevalence of vitamin D deficiency and insufficiency in people with the disease. 
11/5/20
Mirza FN, Malik AA, Omer SB, et al. | Int J Dermatol
Aim: To collate the available information on the dermatologic manifestations in COVID?19 patients to inform current practice and further research.
UPDATED
11/5/20
Cheruiyot I, Sehmi P, Ominde B, et al  | Neurol Sci
Aim: To identify and consolidate evidence of ICH in COVID-19 patients.
11/5/20
Alamoodi AH, Zaidan BB, Zaidan AA, et al. | Expert Syst Appl
Aim: To review and analyse articles about the occurrence of different types of infectious diseases, such as epidemics, pandemics, viruses or outbreaks, during the last 10 years, understand the application of sentiment analysis and obtain the most important literature findings.
11/4/20
Wu Z, Yang D | Eur J Med Res
Aim: To explore the probable clinical severity and mortality of COVID-19 patients and their liver dysfunction.
CLINICAL CHARACTERISTICS
11/4/20
Park R, Lee S, Kim SY, et al  | Acta Oncol
Aim: To summarize the existing evidence for the effect of active oncologic treatment on COVID-19 outcomes.
UPDATED
11/4/20
Zhang H, Han H, He T, et al. | J Natl Cancer Inst
Aim: To review the evidence on the reported fatalities in COVID-19 patients with cancer.
11/4/20
Hessami K, Romanelli C, Chiurazzi M, et al. | J Matern Fetal Neonatal Med
Aim: To evaluate the effect of the COVID-19 pandemic on anxiety and depression of women during pregnancy and perinatal period.
MENTAL HEALTH
11/4/20
Cao K, Kline B, Han Y, et al. | Biomed Res Int
Aim: To estimate the prevalence rate of ocular symptoms and the positive rate of conjunctival swab samples of patients diagnosed with 2019 Novel Coronavirus Disease (COVID-19).
11/4/20
 | NSW Health COVID-19 Critical Intelligence Unit
11/4/20
Hoang T | J Med Virol
Aim: To summarize the current evidence of factors associated with the risk of disease recurrence.
11/4/20
Vizheh M, Qorbani M, Arzaghi SM, et al. | J Diabetes Metab Disord
Aim: To review all research carried out on the mental health status of health care workers (HCWs) to bring policymakers and managers’ attention.
MENTAL HEALTH
11/4/20
Khateri S, Mohammadi H, Khateri R, et al. | Arch Acad Emerg Med
Aim: To determine the prevalence of underlying diseases and associated comorbidities in COVID-19 patients using a systematic review and meta-analysis.
11/4/20
Bashash D, Hosseini-Baharanchi FS, Rezaie-Tavirani M, et al. | Arch Acad Emerg Med
Aim: To provide a well-conceptualized viewpoint demonstrating the prognostic value of thrombocytopenia in COVID-19.
11/3/20
Zhou Y, Ren Q, Chen G, et al.  | Front Med
Aim: To review the evidence on the clinical characteristics of COVID-19 patients, with a focus on the prevalence of CKD and AKI, as well as their association with poor prognosis.
CLINICAL CHARACTERISTICS
11/3/20
Lakbar I, Luque-Paz D, Mege J, et al. | PLoS One
Aim: To systematically review the literature relating to men versus women on SARS-CoV-2 in order to seek differences in disease characteristics (e.g. infectivity, severity) and outcomes (e.g. mortality).
CLINICAL CHARACTERISTICS
11/3/20
O'Neil M, Veazie S, LaFavor B | VA Evidence Synthesis Program
Aim: To compare the prevalence of mental health disorders among adults who have been hospitalized for COVID-19 to relevant comparison groups, assess whether the prevalence of mental health disorders varies by patient and disease characteristics, and ascertain mental health care utilization and resource needs for adults following hospitalization for COVID-19.
UPDATED
VA ESP
MENTAL HEALTH
11/3/20
Mesas AE, Cavero-Redondo I, Alvarez-Bueno C, et al. | PLoS One
Aim: To synthesize the results of primary studies and provide pooled effect size estimators for a comprehensive set of potential predictors of in-hospital mortality in patients with confirmed COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
11/3/20
Lane MY, Winters N, Fregonese F, et al. | PLoS One
Aim: To conduct a systematic review and meta-analysis on the proportion of asymptomatic infection among coronavirus disease 2019 (COVID-19) positive persons and their transmission potential.
UPDATED
CLINICAL CHARACTERISTICS
11/2/20
Boregowda U, Perisetti A, Nanjappa A, et al. | Front Med
Aim: To compare the efficacy of tocilizumab in severe COVID-19 cases vs. standard of care alone.
UPDATED
11/2/20
Dawoud DM, Soliman KY | Value Health
Aim: To review published economic evaluations of antiviral treatment for pandemics and outbreaks of respiratory illnesses.
11/2/20
Saad MA, Alfishawy M, Nassar M, et al. | Curr Rheumatol Rev
Aim: To review the evidence on reported COVID-19 cases with asociated autoimmune manifestations.
11/2/20
Palaiodimos L, Chamorro-Pareja N, Karamanis D, et al. | Hormones
Aim: To systematically review and synthesize with a meta-analysis the available observational studies reporting the effect of diabetes in mortality among hospitalized patients with COVID-19.
UPDATED
11/2/20
Elsawah H, Elsokary M, Abdallah MS, et al. | Rev Med Virol
Aim: To systematically review the use of remdesivir in Covid?19 among the available clinical trials and summarise remdesivir efficacy.
UPDATED
11/2/20
Hariyanto TI, Kristine E, Jillian C, et al. | Infect Disord Drug Targets
Aim: To review the evidence on the use of lopinavir/ritonavir as a potential treatment candidate against COVID-19.
11/2/20
Megnin-Viggars O, Carter P, Melendez-Torres GJ, et al. | PLoS One
Aim: To identify facilitators and barriers to uptake of, and engagement with, contact tracing during infectious disease outbreaks.
11/2/20
Prasitlumkum N, Chokesuwattanaskul R, Thongprayoon C, et al. | Diseases
Aim: To explore the incidence of acute myocardial injury among COVID-19 patients.
11/2/20
Ren L, Yu S, Xu W, et al. | J Cardiol
Aim: To address whether there is an association of antihypertensive medications and the incidence and severity of COVID-19. 
CLINICAL CHARACTERISTICS
11/2/20
Cagnazzo F, Arquizan C, Derraz I, et al. | J Neurol
Aim: To perform an updated review of the literature on the neurological manifestations of COVID-19-infected patients
11/2/20
Trypsteen W, Van Cleemput J, Van Snippenberg W, et al. | PLoS One
Aim: To review the current (pre)published SARS-CoV-2 literature with a focus on the evidence concerning SARS-CoV-2 distribution in human tissues and viral shedding in body fluids.
11/2/20
Shrestha DB, Budhathoki P, Syed N, et al. | Life Sci
Aim: To conduct a systematic review and meta-analysis on remdesivir use for COVID-19.
11/2/20
Ciaffi J, Meliconi R, Ruscitti P, et al. | BMC Rheumatol
Aim: To assess the prevalence of rheumatic manifestations in patients affected by COVID-19, as initial symptom or during disease course.
11/2/20
Lee KW, Khan AHKY, Ching SW, et al. | Front Neurol
Aim: To perform a systematic review and meta-analysis of currently available epidemiological, clinical, and laboratory data related to both stroke and COVID-19 infection.
11/2/20
Violante T, Violante FS | Med Lav
Aim: To summarize the available studies which have compared the respective effectiveness of surgical masks and filtering facepiece respirators  for the prevention of infections caused by viruses that are transmitted by the respiratory tract.
11/2/20
Antony AR, Haneef Z | Seizure
Aim: To synthesize the data on EEG findings in COVID-19.
11/2/20
Kolcun JPG, Ryu WHA, Traynelis VC | J Neurosrug Spine
Aim: To examine the current utilization of TM for spine surgery.
11/2/20
Del Riccio M, Lorini C, Bonaccorsi G, et al. | Int J Environ Res Public Health
Aim: To review the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g. severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients.
UPDATED
11/2/20
Chen J, Wu C, Wang X, et al. | Front Endocrinol
Aim: To summarize available data on the association between glycemic parameters and severity of COVID-19.
11/1/20
Wen W, Zhang H, Zhou M, et al. | Eur Rev Med Pharmacol Sci
Aim: To evaluate arrhythmia in patients with severe and non-severe COVID-19 during the current COVID-19 pandemic.
CLINICAL CHARACTERISTICS
11/1/20
Lim JL, Reddy MP, Afroz A, et al. | Resuscitation
Aim: To evaluate the influence of the COVID-19 pandemic on the incidence, process, and outcomes of OHCA.
UPDATED
CLINICAL CHARACTERISTICS
11/1/20
Comas-Herrera A, Salcher-Konrad M, Baumbusch J, et al. | LTC Responses to COVID-19
Aim: To review the evidence on the impact of visitors in terms of infections in care homes, closing care homes to visitors, and restricting visits on quality of care.
10/31/20
Sanghera J, Pattani N, Hashmi Y, et al. | J Occup Health
Aim: To determine the impact of SARS?CoV?2 on mental health outcomes of hospital?based HCWs and formulate recommendations for future action.
UPDATED
MENTAL HEALTH
10/30/20
Ghayda RA, Li H, Lee KH, et al. | J Clin Med
Aim: To synthesize the most up-to-date and relevant available evidence on the outcomes of pregnant women with laboratory-confirmed infection with COVID-19.
CLINICAL CHARACTERISTICS
10/30/20
Ebrahimi M, Malehi AS, Rahim F | Osong Public Health Res Perspect
Aim: To compare coronavirus disease 2019 (COVID-19) laboratory findings, comorbidities, and clinical outcomes in patients from the general population versus medical staff to aid diagnosis of COVID-19 in a more timely, efficient, and accurate way.
DIAGNOSTICS
10/30/20
D'Errico S, Zanon M, Montanaro M, et al. | Microorganisms
Aim: To summarize all autopsy studies up to February 2020 in which a complete post-mortem investigation in patients with COVID-19 disease was performed, focusing on histopathological features. 
CLINICAL CHARACTERISTICS
10/30/20
Egunsola O, Hofmeister M, Dowsett LE, et al. | University of Calgary
Aim: To review the evidence on the control and management of COVID-19, SARS, or MERS in adults 60 years or above living in long-term care facilities.
10/30/20
Dong Z, Xiang B, Jiang M, et al. | Clin Gastroenterol
Aim: To investigate the prevalence of GI symptoms, abnormal liver function, digestive system disease and liver disease in patients with COVID-19 by a systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
10/30/20
Arora T, Grey I, Ostlundh L, et al. | J Health Psychol
Aim: To examine the overall prevalence of psychological health outcomes during COVID-19. 
UPDATED
MENTAL HEALTH
10/29/20
Munteanu C, Paun D, Suta A, et al. | Balneo Research Journal
Aim: To identify the main possible interferences between DM and COVID-19's pathological mechanisms, and to discuss the value of physical and rehabilitation medicine and balneotherapy in the post-acute COVID-19 recovery of the surviving patients
CLINICAL CHARACTERISTICS
10/29/20
Aggarwal G, Lippi G, Lavie CJ, et al.  | J Diabetes
Aim: To evaluate the potential assocations between diabetes mellitus and infection severity outcomes in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/29/20
Patel U, Malik P, Mehta D, et al. | J Glob Health
Aim: To evaluate epidemiological characteristics, needs of resources, outcomes, and global burden of the disease.
10/29/20
Khan M, Khan N, Mustagir G, et al. | J Glob Health
Aim: To summarize pre-existing comorbidities in patients with COVID-19, and to estimate the likelihood of mortality from COVID-19 with each category of pre-existing comorbidities.
UPDATED
CLINICAL CHARACTERISTICS
10/29/20
Kumar R, Nedungalaparambil NM, Mohanan N | J Family Med Prim Care
Aim: To review the evidence on emergency and primary care collaborations during the COVID-19 pandemic.
10/29/20
PHAC Emerging Science Group | Public Health Agency of Canada
Aim: To review the evidence on whether hosptialized SARS-CoV-2 patients that successfully recover with no subsequently positive RT-PCR tests present with SARS-CoV-2 antibody levels or seropositivity rates differ from those that do retest positive?
10/29/20
Ramos-Lopez O, Daimiel L, de Molina AR, et al. | Int J Genomics
Aim: To systematically explore genetic polymorphisms associated with the clinical outcomes in SARS-CoV infection in humans.
CLINICAL CHARACTERISTICS
10/29/20
Mohammadi M, Rajabnia M, Abdehagh M | Sci J Kurd Univ Med Sci
Aim: To review the gastrointestinal manifestations in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/29/20
Hasan I, Saif-Ur-Rahman KM, Hayat S, et al. | J Peripher Nerv Syst
Aim: To summarize and meta?analyze the salient features and prognosis of SARS?CoV?2?associated GBS.
CLINICAL CHARACTERISTICS
10/29/20
Asghar M, Hussan N, Shoaib H, et al. | J Community Hosp Intern Med Perspect
Aim: To assess hematological changes seen in COVID-19 infection and their association with the severity of the disease.
CLINICAL CHARACTERISTICS
10/29/20
Ling XC, Kang EY, Lin J, et al. | Taiwan J Ophthalmol
Aim: To provide general guidance for ophthalmologists to understand the prevalence of ocular presentation in COVID 19 patients and to reduce the risk of transmission during practice.
INFECTION CONTROL
10/29/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the effectiveness of fit testing and fit checking for testing the protection of a respirator.
10/29/20
Milby KM, Atallah AN, Rocha-Filho CR, et al. | Sao Paulo Med J
Aim: To understand and summarize the evidence relating to clinical manifestations, disease severity and prognoses among patients coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and arboviruses.
UPDATED
CLINICAL CHARACTERISTICS
10/29/20
Jahrami H, BaHammam AS, Bragazzi NL, et al. | J Clin Sleep Med
Aim: To assess the impact and prevalence of sleep problems among the general population, healthcare workers, and COVID-19 patients.
MENTAL HEALTH
10/28/20
Comber L, Murchu EO, Drummond L, et al. | Rev Med Virol
Aim: To synthesise the evidence for the potential airborne transmission of SARS-CoV-2 via aerosols.
INFECTION CONTROL
10/28/20
Mora-Ramirez M, Melgoza-Hernandez P, Toledo-Ramirez SE, et al. | Curr Med Chem
Aim: To review the main adverse effects regarding the most prescribed drugs and, specifically, the efficacy and potential risk of each pharmacological therapy, during hospital care for COVID-19.
CANDIDATE THERAPEUTICS
10/28/20
Cano EJ, Fuentes XF, Campioli CC, et al. | Chest
Aim: To review the evidence on the impact of corticosteroids in mortality, ICU admission, mechanical ventilation, and viral shedding in COVID-19 patients.
CANDIDATE THERAPEUTICS
10/28/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the contributing factors of a second spike in COVID-19 cases.
10/28/20
Amanullah S, Shankar RR | Healthcare
Aim: To analyse and summarise the current knowledge on factors/potential factors contributing to burnout amongst healthcare professionals amidst the pandemic. 
MENTAL HEALTH
10/27/20
Wijeratne T, Sales C, Karimi L, et al.  | Front Neurol
Aim: To review the clinical data on all published cases of COVID-19 and concomitant AIS, with a view to understanding the pertinent clinical, laboratory and imaging features.
CLINICAL CHARACTERISTICS
10/27/20
Lu Q, Wang Z, Yin Y, et al. | Front Med
Aim: To investigate the evidence on the association between peripheral lymphocyte levels and the progression and mortality of COVID-19.
CLINICAL CHARACTERISTICS
10/27/20
Budhathoki P, Shrestha DB, Rawal E, et al. | SN Compr Clin Med
Aim: To assess the rationality on the use of corticosteroids in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/27/20
Nannoni S, de Groot R, Bell S, et al.  | Int J Stroke
Aim: To characterize the incidence, risk factors, clinical-radiological manifestations and outcome of COVID-19-associated stroke.
CLINICAL CHARACTERISTICS
10/27/20
Hojaij FC, Chinelatto LA, Boog GHP, et al.  | Int Arch Otorhinolaryngol
Aim: To provide an easy access to and a trustful review of the main aspects that have changed in the head and neck surgery and otorhinolaryngology practice due to the COVID-19 pandemic.
INFECTION CONTROL
10/27/20
Mehraeen E, Karimi A, Barzegary A, et al.  | Eur J Integr Med
Aim: To systematically review the assessment of risk and model the predictors of mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/27/20
Chen X, Zhang G, Hao SY, et al. | Chin Med Sci J
Aim: To compare the similarities and differences of early CT manifestations of three types of viral pneumonia induced by SARS-CoV-2 (COVID-19), SARS-CoV (SARS) and MERS-CoV (MERS) using a systemic review.
CLINICAL CHARACTERISTICS
10/27/20
Szegedi I, Orbán-Kálmándi R, Csiba L, et al. | J Clin Med
Aim: To summarize the available literature on COVID-19-associated coagulopathy and thrombosis and to identify the characteristics of stroke in COVID-19.
CLINICAL CHARACTERISTICS
10/27/20
Pranata R, Supriyadi R, Huang I, et al.  | Clin Med Insights Circ Respir Pulm Med
Aim: To evaluate the association between chronic kidney disease (CKD) and new onset renal replacement therapy (RRT) with the outcome of Coronavirus Disease 2019 (COVID-19) in patients.
CLINICAL CHARACTERISTICS
10/27/20
Bansal A, Singh AD, Jain V, et al.  | Heart & Lung
Aim: To determine if D-dimers are elevated in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who have adverse clinical outcomes including all-cause mortality, intensive care unit (ICU) admission or acute respiratory distress syndrome (ARDS).
CLINICAL CHARACTERISTICS
10/27/20
Valencia-Enciso N, Ortiz-Pereira M, Zafra-Sierra MP, et al. | J Stroke Cerebrovasc Dis
Aim: To assess the temporal relationship between COVID-19 severity and stroke onset. To determine if characteristics such as presentation of the stroke, younger age, involvement of large vessel occlusion and pattern of paraclinical markers could be distinct from the no-COVID-19 population.
CLINICAL CHARACTERISTICS
10/26/20
Comber L, Walsh KA, Jordan K, et al. | Rev Med Virol
Aim: To synthesise the available evidence for detection of SARS?CoV?2 RNA using RT?PCR tested saliva or nasal specimens compared with RT?PCR tested nasopharyngeal specimens.
DIAGNOSTICS
10/26/20
Weatherald J, Solverson K, Zuege DJ, et al. | J Crit Care
Aim: To quickly identify and synthesize studies examining the effect of awake prone positioning on patients with hypoxemic respiratory failure (including those with ARDS and/or COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
10/26/20
Zeng L, Wang S, Cai J, et al. | Epidemiol Infect
Aim: To determine the potential risk factors for cardiac injury complicated COVID-19 virus infection.
CLINICAL CHARACTERISTICS
10/26/20
Yee JY, Kim WK, Han JMH, et al. | Sci Rep
Aim: To evaluate the impact of COVID-19 on pregnant women.
UPDATED
CLINICAL CHARACTERISTICS
10/26/20
Mirzaie H, Vahidi M, Shokoohi M, et al. | medRxiv
Aim: To summarize the evidence on COVID-19 patients with HBV or HCV co-infections. 
10/26/20
Mch SA, Baishya M, Singh A, et al. | Trends Anaesthesia Crit Care
Aim: To conduct a systematic review of the available literature to highlight the effect of awake proning on the need for intubation, improvement in oxygenation and mortality rates in COVID-19 patients with ARDS.
CANDIDATE THERAPEUTICS
10/26/20
Hu C, Liang M, Gong F, et al. | Evid Based Complement Alternat Med
Aim: To investigate and compare the therapeutic effect of Lianhua Qingwen with conventional drugs on pneumonia symptoms.
CANDIDATE THERAPEUTICS
10/26/20
Chaabna K, Doraiswamy S, Mamtani R, et al. | Int J Infect Dis
Aim: To inform policymakers and stakeholders by examining and synthesizing available evidence on the effectiveness of cloth and medical facemasks for preventing transmission of respiratory infections in community settings and pointing out the gaps in evidence.
INFECTION CONTROL
10/26/20
Gu ZC, Zhang C, Kong LC, et al. | Cardiovasc Diagn Ther
Aim: To summarize all available evidence for a comprehensive and rigorous systematic review focused on myocardial injury incidence in COVID-19. In addition, to state the case-fatality rate related to cardiac injury, variations of myocardial injury incidence were also examined by disease severity (non-survivors, severe patients, and non-severe patients).
CLINICAL CHARACTERISTICS
10/26/20
Wang H, Ai J, Loeffelholz MJ, et al. | Emerg Microbes Infect
Aim: To evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals.
DIAGNOSTICS
10/26/20
Malik P, Patel U, Patel K, et al. | J Med Virol
Aim: To assess the effect of obesity on outcomes in the COVID-19 hospitalizations.
CLINICAL CHARACTERISTICS
10/26/20
Javanmardi F, Keshavarzi A, Akbari A, et al. | PLoS One
Aim: To evaluate the prevalence of underlying disease in died people with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/26/20
Vazzana N, Dipaola F, Ognibene S | Acta Clin Belg
Aim: To review the prognostic value of procalcitonin for severe disease and adverse outcome events in COVID-19.
CLINICAL CHARACTERISTICS
10/26/20
de Labry-Lima AO, Bermudez-Tamayo C, Martinez-Olmos J, et al. | Enferm Infecc Microbiol Clin
Aim: To compile the available evidence on the use of masks in relation to respiratory infections.
INFECTION CONTROL
10/26/20
Wang Y, Chen B, Li Y, et al. | J Med Virol
Aim: To investigate the effects of ACEI/ARB on COVID-19 patients.
CANDIDATE THERAPEUTICS
10/25/20
Kotak S, Khatri M, Malik M, et al. | Cureus
Aim: To assess the safety and efficacy of tocilizumab as compared to the standard regimen in patients with COVID-19.
CANDIDATE THERAPEUTICS
10/23/20
Bwire GM, Nijiro BJ, Mwakawanga DL, et al. | J Med Virol
Aim: To determine the likelihood of vertical transmission among COVID-19 exposed infants and to determine whether antibodies against Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/ COVID-19 virus exist among COVID-19 vertically exposed but negative infants.
CLINICAL CHARACTERISTICS
10/23/20
La Distia Nora R, Putera I, Khalisha DF, et al. | BMJ Open Ophthalmol
Aim: To review and critically appraise the ocular manifestation and the presence of SARS-CoV-2 through PCR positivity from ocular samples in COVID-19-related patients. Moreover, to evaluate the time and severity association of ocular manifestation to systemic disease of COVID-19.
CLINICAL CHARACTERISTICS
10/23/20
Yamakawa M, Kuno T, Mikami T, et al. | J Stroke Cerebrovasc Dis
Aim: To depict the frequency and clinical characteristics of COVID-19 patients with stroke.
CLINICAL CHARACTERISTICS
10/23/20
Guo L, Shi Z, Zhang Y, et al. | Diabetes Res Clin Pract
Aim: To assess the association of comorbid diabetes with COVID-19 severity or mortality in China.
CLINICAL CHARACTERISTICS
10/23/20
Wang JG, Cui HR, Tang HB, et al. | Sci Rep
Aim: To understand the clinical manifestations and incidence of gastrointestinal symptoms of Coronavirus disease (COVID-19) in children and discuss the importance of fecal nucleic acid testing.
UPDATED
CLINICAL CHARACTERISTICS
10/23/20
Favas TT, Dev P, Chaurasia RN, et al. | Neurol Sci
Aim: To estimate the proportion of COVID-19 patients developing neurological manifestations.
CLINICAL CHARACTERISTICS
10/23/20
Raymond C, Loshak H | CADTH
Aim: To describe the trial characteristics and estimated primary completion dates of the ongoing phase II, phase III, and phase IV studies evaluating IVIg and hyperimmune globulin to treat COVID-19.
UPDATED
10/23/20
Wang C, Zhang H, Zhou Y, et al. | Eur Rev Med Pharmacol Sci
Aim: To explore the relationship between the prognosis of COVID-19 patients and thromboembolic events.
CLINICAL CHARACTERISTICS
10/22/20
Wijaya I, Andhika R, Huang I | Clin Appl Thromb Hemost
Aim: To explore the association between therapeutic-dose anticoagulation and its effect on mortality in patients with COVID-19.
CANDIDATE THERAPEUTICS
10/22/20
Kurdi A, Abutheraa N, Akil L, et al. | Pharmacol Res Perspect
Aim: To provide a comprehensive/updated evaluation of the effect of ACEIs/ARBs on COVID?19?related clinical outcomes, including exploration of interclass differences between ACEIs and ARBs.
CANDIDATE THERAPEUTICS
10/22/20
Fong V, Iarocci G | J Pediatr Psychol
Aim: To evaluate the quality of existing studies on this topic, determine what is known about mental health outcomes and needs of children and families, and provide recommendations for how COVID-19 policies can best support children and families
UPDATED
MENTAL HEALTH
10/22/20
Qadri SK, Ng P, Toh TSW, et al. | Pulm Ther
Aim: To describe the mechanisms of action of prone position, systematically appraise the current experience of prone position in COVID-19 patients, and highlight unique considerations for prone position practices during this pandemic.
CANDIDATE THERAPEUTICS
10/22/20
Sepandi M, Taghdir M, Alimohamadi Y, et al. | Iran J Public Health
Aim: To identify effective factors on the death among COVID-19 patients.
CLINICAL CHARACTERISTICS
10/22/20
Hernandez AV, Roman YM, Pasupuleti V, et al. | Ann Intern Med
Aim: To summarize evidence about the benefits and harms of hydroxychloroquine or chloroquine for the treatment or prophylaxis of coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
10/22/20
Ibrahim W | CNS Spectr
Aim: To systematically assess the neurological manifestations in patients diagnosed with COVID-19
CLINICAL CHARACTERISTICS
10/22/20
Chew QH, Wei KC, Vasoo S, et al. | J Clin Psychiatry
Aim: To learn from past infectious disease outbreaks to provide better psychological support for our frontline health care workers (HCW) by conducting a rapid review of extant studies that have reported on both psychological and coping responses in HCW during recent outbreaks.
MENTAL HEALTH
10/22/20
Perras C, Pohar S, Manoharan A, et al. | CADTH
Aim: To review the current scientific evidence on the potential benefits and harms of remdesivir.
UPDATED
10/22/20
Haradaa G, Antonacio FF, Gongora AB, | Ecancermedicalscience
Aim: To address the question of whether to test asymptomatic cancer patients before initiating systemic cancer treatments.
CLINICAL CHARACTERISTICS
10/22/20
Andrews E, Berghofer K, Long J, et al. | Int J Nurs Adv
Aim: To examine current evidence on patient and healthcare provider's satisfaction with the use of telehealth during the COVID-19 pandemic
INFECTION CONTROL
10/22/20
Ayele Mega T, Feyissa TM, Dessalegn Bosho D, et al. | Can Respir J
Aim: To generate an up-to-date evidence for the clinical safety and efficacy of hydroxychloroquine (HCQ) with or without azithromycin (AZ) among patients treated for COVID-19.
CANDIDATE THERAPEUTICS
10/21/20
Leisman DE, Ronner L, Pinotti R, et al. | Lancet Respir Med
Aim: To synthesise and describe the reported pattern of inflammatory cytokines in COVID-19-induced respiratory failure and to compare this profile with those of other acute inflammatory syndromes.
UPDATED
CLINICAL CHARACTERISTICS
10/21/20
Cheng L, Li H, Li L, et al. | J Clin Lab Anal
Aim: To determine the role of ferritin in COVID?19.
CLINICAL CHARACTERISTICS
10/21/20
Agstam S, Yadav A, Kumar MP, et al. | Indian Pacing Electrophysiol J
Aim: To study the risk of QTc prolongation and Torsades de pointes (TdP) by a well-defined criterion for HCQ, CQ alone, and in combination with Azithromycin in patients with COVID-19.
CANDIDATE THERAPEUTICS
10/21/20
Kefale B, Tegegne GT, Degu A, et al. | Clin Appl Thromb Hemost
Aim: To investigate the extent and risk factors of thromboembolism among COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/21/20
Nguyen VT, Riviere P, Ripoll P, et al. | J Clin Epidemiol
Aim: To describe the planning of randomized controlled trials (RCTs) in terms of timing related to the course of the COVID-19 epidemic and research question evaluated.
10/21/20
Bhattacharyya A, Kumar S, Sarma P, et al. | Indian J Pharmacol
Aim: To evaluate the safety as well as efficacy of L/R combination therapy in the management of COVID-19.
CANDIDATE THERAPEUTICS
10/21/20
Yang H, Lan Y, Yao X, et al. | Virol J
Aim: To summarize the characteristics of chest CT imaging in Chinese hospitalized patients with Coronavirus Disease 2019 (COVID-19) to provide reliable evidence for further guiding clinical routine.
DIAGNOSTICS
10/21/20
Xu J, Teng Y, Shang L, et al. | Clin Infect Dis
Aim: To provide a comprehensive summarization of current evidence to answer two major clinical questions: (1) Does the prior treatment of ACEI/ARB alter the susceptibility of SARS-CoV-2 infection in general population? (2) Does the prior treatment of ACEI/ARB affect risk of mortality and severe outcomes in COVID-19 patients?
UPDATED
CLINICAL CHARACTERISTICS
10/20/20
da Silva PG, Nascimento MSJ, Soares RRG, et al. | Sci Total Environ
Aim: To review the evidence on the viability/stability of aerosols containing SARS-CoV and MERS-CoV viruses.
INFECTION CONTROL
10/20/20
Yonas E, Alwi I, Pranata R, et al. | Am J Emerg Med
Aim: To investigate the association between heart failure (HF) and poor outcome in patients with COVID-19.
CLINICAL CHARACTERISTICS
10/20/20
Gungor B, Atici A, Baycan OF, et al. | Am J Emerg Med
Aim: To investigate the correlation of D-dimer levels measured on admission with disease severity and the risk of death in patients with coronavirus disease 2019 (COVID-19) pneumonia.
CLINICAL CHARACTERISTICS
10/20/20
Tan E, Song J, Deane AM, et al. | Chest
Aim: To review the evidence on the global point estimate of mortality and risk factors for patients admitted to intensive care units (ICUs) with severe COVID-19.
CLINICAL CHARACTERISTICS
10/20/20
Wassie GT, Azene AG, Bantie GM, et al. | Curr Ther Res Clin Exp
Aim: To estimate the pooled average incubation period of SARS-CoV-2.
CLINICAL CHARACTERISTICS
10/20/20
Chua TH, Xu Z, King NKK | Brain Inj
Aim: To determine the clinical characteristics of neurological manifestations in COVID-19.
CLINICAL CHARACTERISTICS
10/20/20
Kotecha P, Light A, Checcucci E, et al. | Panminerva Med
Aim: To evaluate the data currently available regarding the repurposing of different drugs for Covid-19 treatment. 
UPDATED
CANDIDATE THERAPEUTICS
10/20/20
Sun C, Sun Y, Li X | Am J Emerg Med
Aim: To evaluate the clinical efficacy and safety of CM in the treatment of COVID-19 pneumonia.
CANDIDATE THERAPEUTICS
10/20/20
Hossein H, Ali KM, Hosseini M, et al. | Clin Transl Imaging
Aim: To answer to the question whether CT scan can be used in diagnosis of COVID-19 or not.
DIAGNOSTICS
10/19/20
Fram G, Wang D, Malette K, et al. | Curr Cardiol Rev
Aim: To evaluate the incidence of cardiotoxicity associated with hydroxychloroquine prior to onset of the COVID-19 pandemic.
CANDIDATE THERAPEUTICS
10/19/20
Liu Y, Lu H, Wang W, et al. | Expert Rev Anticancer Ther
Aim: To identify the risk factors for death in patients with cancer and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Mulchandani R, Lyngdoh T, Kakkar AK | Eur J Clin Invest
Aim: To quantify the differences in the circulating levels of major inflammatory and immunological markers between severe and non?severe COVID?19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Ortega KL, Rech BO, El Haje GLC, et al. | J Hosp Infect
Aim: To review the evidence on whether hydrogen peroxide mouthwash has a virucidal effect.
UPDATED
INFECTION CONTROL
10/19/20
Jena A, Kumar-M P, Singh AK, et al. | Dig Liver Dis
Aim: To study the elevations of fecal calprotectin in COVID-19 and if these elevations were different in patients with or without gastrointestinal symptoms.
CLINICAL CHARACTERISTICS
10/19/20
Tasar R, Wiegand C, Elsner P | Contact Dermatitis
Aim: To review the evidence on the irritant effects of alcoholic hand rubs.
INFECTION CONTROL
10/19/20
Cantini F, Goletti D, Petrone L, et al. | Drugs
Aim: To assess the clinical impact of different therapies for COVID-19.
CANDIDATE THERAPEUTICS
10/19/20
July J, Pranata R | J Stroke Cerebrovasc Dis
Aim: To evaluate the impact of the coronavirus disease (COVID-19) pandemic on stroke care, including the number of stroke alerts/codes, number of reperfusions, and number of thrombectomies during the pandemic compared to those during the pre-pandemic period.
INFECTION CONTROL
10/19/20
 | CADTH
Aim: To review the various strategies being used to increase the availability of N95 masks.
10/19/20
Abate SM, Mantefardo B, Basu B | Patient Saf Surg
Aim: To provide the global prevalence of perioperative outcomes of patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Chamseddine RS, Wahbeh F, Chervenak F, et al. | J Pregnancy
Aim: To review the evidence on preinatal and obstetric management in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Raschetti R, Vivanti AJ, Vauloup-Fellous C, et al. | Nat Commun
Aim: To clarify the main transmission route, clinical features and outcomes of neonatal SARS-CoV-2 infections
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Ramaraj P, Super JT, Doyle R, et al. | BMJ Open
Aim: To review the evidence behind UK Government PPE guidance on surgical masks versus respirators for SARS-CoV-2 protection.
UPDATED
INFECTION CONTROL
10/19/20
Pluddemann A, Aronson JK | Oxford COVID-19 Evidence Service
Aim: To review the evidence on the role of T cells and antibodies in immunity to COVID-19 infection.
10/18/20
Walker C, Deb S, Ling H, et al. | J Pharm Pharm Sci
Aim: To assess the association between elevated cardiac biomarkers and the severity of COVID-19 infection.
CLINICAL CHARACTERISTICS
10/17/20
Zhang P, Shi L, Xu J, et al.  | Immunogenetics
Aim: To evaluate the association of interleukin-6 (IL-6) level with the poor outcomes in coronavirus disease 2019 (COVID-19) patients. 
CLINICAL CHARACTERISTICS
10/16/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on factors that may help protect Indigenous peoples and communities in Canada and internationally from the COVID-19 pandemic and its impacts.
10/16/20
Bhatia R, Pedapati R, Komakula S, et al. | J Stroke
Aim: To report the characteristics of stroke in patients with COVID-19.
CLINICAL CHARACTERISTICS
10/15/20
Gonzalez-Rubio J, Navarro-Lopez C, Lopez-Najera E, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the epidemiologic relationship between smoking and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/15/20
Apostolopoulou A, Garrigos ZE, Vijayvargiya P, et al. | Diagnostics
Aim: To investigate the epidemiology, pathogenesis, risk factors, clinical manifestations, diagnosis, treatment and prognosis of COVID-19 associated pulmonary aspergillosis (CAPA).
CLINICAL CHARACTERISTICS
10/15/20
 | NSW Health COVID-19 Critical Intelligence Unit
10/15/20
Akiyama S, Hamdeh S, Micic D, et al. | Ann Rheum Dis
Aim: To assess the prevalence and clinical outcomes of COVID-19 in autoimmune diseases.
CLINICAL CHARACTERISTICS
10/15/20
Du M, Lin Y, Yan W, et al. | World J Diabetes
Aim: To systematically evaluate the prevalence of diabetes among COVID-19 patients in China and its impact on clinical outcomes, including ICU admission, progression to severe cases, or death.
CLINICAL CHARACTERISTICS
10/15/20
Chu IY, Alam P, Larson H, et al. | J Travel Med
Aim: To identify: 1) the social consequences of mass quarantine—community-wide movement restrictions—during previous and current infectious disease outbreaks, and 2) recommended strategies to mitigate the negative social implications of COVID-19 lockdowns. 
UPDATED
MENTAL HEALTH
10/15/20
Walsh KA, Spillane S, Comber L, et al. | J Infect
Aim: To summarise the evidence on the duration of infectiousness of individuals in whom SARS-CoV-2 ribonucleic acid is detected.
CLINICAL CHARACTERISTICS
10/14/20
Dehaghi BF, Ghodrati-Torbati A, Teimori G, et al. | Invest Educ Enferm
Aim: To assess the effectiveness of face masks against the novel coronavirus. 
INFECTION CONTROL
10/14/20
Pang KW, Chee J, Subramaniam S, Ng CL | Curr Allergy Asthma Rep
Aim: To quantify the clinical utility of identifying OD in the diagnosis of COVID-19 and determine an estimate of the frequency of OD amongst these patients.
CLINICAL CHARACTERISTICS
10/14/20
Fung HF, Martinez L, Alarid-Escudero F, et al. | Clin Infect Dis
Aim: To review the evidence on the transmission of SARS-CoV-2 within households.
INFECTION CONTROL
10/13/20
Bansal A, Singh AD, Jain V, et al. | Heart Lung
Aim: To determine if D-dimers are elevated in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who have adverse clinical outcomes including all-cause mortality, intensive care unit (ICU) admission or acute respiratory distress syndrome (ARDS).
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Jackson T, Deibert D, Wyatt G, et al. | BMJ Open Respir Res
Aim: To review how official guidance documents and academic publications have classified procedures in terms of whether or not they are aerosol-generating. 
INFECTION CONTROL
10/13/20
Pormohammad A, Ghorbani S, Khatami A, et al. | Rev Med Virol
Aim: To compare clinical symptoms, laboratory findings, radiographic signs and outcomes of COVID?19 and influenza to identify unique features.
CLINICAL CHARACTERISTICS
10/13/20
Chai KL, Valk SJ, Piechotta V, et al. | Cochrane Database Syst Rev
Aim: To assess whether convalescent plasma or hyperimmune immunoglobulin transfusion is effective and safe in the treatment of people with COVID?19.
UPDATED
CANDIDATE THERAPEUTICS
10/13/20
Banakar M, Lankarani KB, Jafarpour D, et al. | BMC Oral Health
Aim: To examine the risk of the transmission of the COVID–19 during dental treatments and provides pathways and protective protocols to minimize them, bearing in mind the long-term necessity of actions and realistic, practical measures.
UPDATED
INFECTION CONTROL
10/13/20
Singh H, Kaur H, Singh K, et al. | Adv Wound Care
Aim: To review the evidence on cutaneous manifestations reported in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/13/20
Aggarwal N, Garg M, Dwarakanathan V, et al. | J Travel Med
Aim: To review the evidence on the diagnostic accuracy of infrared thermal screening via handheld non-contact infrared thermometers and thermal scanners.
DIAGNOSTICS
10/13/20
Roshandel R, Nateqi M, Lak R, et al. | Cell Mol Biol
Aim: To review the evidence on the diagnostic and methodological evaluation of urinary shedding of SARS-CoV-2.
UPDATED
DIAGNOSTICS
10/13/20
Kashour ZT, Riaz M, Garbati M, et al. | J Antimicrob Chemother
Aim: To systematically evaluate the effect of CQ and HCQ with or without azithromycin (AZ) on outcomes of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/13/20
Nugroho J, Wardhana A, Mulia EP, et al.  | Clin Hemorheol Microcirc
Aim: To determine the relationship between fibrinogen and FDP with poor outcome in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/13/20
Prodromos C, Rumschlag T | New Microbes New Infect
Aim: To review the efficacy of HCQ against COVID-19.
CANDIDATE THERAPEUTICS
10/13/20
Sathian B, Asim M, Banerjee I, et al. | Nepal J Epidemiol
Aim: To assess the impact of the COVID-19 pandemic on the conduction of clinical trials and research.
INFECTION CONTROL
10/13/20
Sajid MI, Awais S, Salar K, et, al. | Biomedica
Aim: To evaluate the pathogenesis, risk factors, diagnosis and management strategies in pregnant women suspected or confirmed with COVID-19 infection.
CLINICAL CHARACTERISTICS
10/13/20
Han SM, Greenfield G, Majeed A, et al. | J Med Internet Res
Aim: To summarize evidence on the impact of remote consultation in primary care on antibiotic prescribing.
INFECTION CONTROL
10/13/20
Tamuzi JL, Ayele BT, Shumba CS, et al. | BMC Infect Dis
Aim: To review different studies on SARS-CoV, MERS-CoV or COVID-19 associated with HIV/TB co-infection or only TB and to understand the interactions between HIV, TB and COVID-19 and its implications on the burden of the COVID-19 among HIV/TB co-infected or TB patients, screening algorithm and clinical management.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Malaty M, Kayes T, Amarasekera AT, et al. | Eur J Clin Invest
Aim: To examine the current incidence and available treatment for arrhythmias in hospitalized patients with SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Gidari A, Nofri M, Saccarelli L, et al. | Eur J Clin Microbiol Infect Dis
Aim: To review the evidence on the recurrence of coronavirus disease 2019.
CLINICAL CHARACTERISTICS
10/13/20
Hariri LP, North CM, Shih AR, et al. | Chest
Aim: To review the evidence on the lung histopathology described in COVID-19 compared to SARS and H1N1 influenza.
CLINICAL CHARACTERISTICS
10/13/20
Nopp S, Moik F, Jilma B, et al. | Res Pract Thromb Haemost
Aim: To evaluate available data and estimating the prevalence of VTE in COVID?19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Singh S, Desai R, Gandhi Z, et al. | SN Compr Clin Med
Aim: To identify COVID-19-associated TTS case reports and evaluate patient-level demographics, clinical attributes, and outcomes. 
CLINICAL CHARACTERISTICS
10/13/20
Elsayed S, Reddy M, Murthy PM, et al. | Cureus
Aim: To identify the trends of COVID-19 relapse, the effects of co-morbidities on it, and associated mortality rates.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Koh WC, Naing L, Chaw L, et al. | PLoS One
Aim:  To estimate the secondary attack rate (SAR) in various settings and to examine whether household transmission differed by symptom status of index case, adult and children (< 18 years old), and relationship to index case.
INFECTION CONTROL
10/12/20
Abdelmoneim AH, Mustafa MI, adlan RHA, et al. | Sudan J Med Sci
Aim: To report and summarize the published evidence on the role of convalescent plasma therapy in the current COVID-19 pandemic.
CANDIDATE THERAPEUTICS
10/12/20
Ali AHM, Mohamed SOO, Elkhidir IHE, et al. | Sudan J Med Sci
Aim: To investigate the association of lymphocyte count, CRP, LDH, and D-Dimer with the severity of COVID-19.
CLINICAL CHARACTERISTICS
10/10/20
Yokoyama Y, Aikawa T, Takagi H, et al. | J Med Virol
Aim: To investigate the effect of ACEI and ARB on mortality and susceptibility to COVID-19.
CANDIDATE THERAPEUTICS
10/9/20
Li Y, Li J, Zhang Y, et al. | Chin J Integr Med
Aim: To systematically review the clinical practice guidelines for the treatment of coronavirus disease 2019 (COVID-19) patients with Chinese herbal medicine (CHM), summarize their recommendations and evaluate their qualities.
CANDIDATE THERAPEUTICS
10/9/20
Toomey E, Conway Y, Burton C, et al. | Infect Control Hosp Epidemiol
Aim: To review the evidence on the extended use or re-use of single-use respirators and surgical masks by frontline healthcare workers.
INFECTION CONTROL
10/9/20
Abate BB, Kassie AM, Kassaw MW, et al. | BMJ Open
Aim: To assess the sex difference in the prevalence of COVID-19 confirmed cases.
CLINICAL CHARACTERISTICS
10/8/20
Maiese A, Manetti AC, La Russa R, et al. | Forensic Sci Med Pathol
Aim: To collect the currently available pathological data on COVID-19 and review the international literature on the postmortem findings of patients with COVID-19.
CLINICAL CHARACTERISTICS
10/8/20
Gianola S, Jesus TS, Bargeri S, et al. | PLoS One
Aim: To take a snapshot of the amount of scientific development devoted to COVID-19 and gain an idea of the current status of global research. 
10/8/20
Quesada JA, López-Pineda A, Gil-Guillén VF, et al. | Rev Clin Esp
Aim: To provide a more accurate estimate of the incubation period of COVID-19.
CLINICAL CHARACTERISTICS
10/8/20
Ehaideb SN, Abdullah ML, Abuyssin B, et al. | Crit Care
Aim: To assess whether the newly created models reproduce the full spectrum of human COVID-19.
10/8/20
Oliveira CB, Lima CAB, Vajgel G, et al. | J Clin Pathol
Aim: To describe the incidence of AKI, need for renal replacement therapy (RRT) and mortality among patients with COVID-19-associated AKI.
CLINICAL CHARACTERISTICS
10/8/20
Henssler J, Stock F, van Bohemen J, et al. | Eur Arch Psychiatry Clin Neurosci
Aim: To assess the psychological effects in both quarantined and isolated persons compared to non-quarantined and non-isolated persons. 
UPDATED
MENTAL HEALTH
10/8/20
Choi GJ, Kim HM, Kang H, et al. | J Lipid Atheroscler
Aim: To analyze the available knowledge about the potential association between dyslipidemia and the severity of coronavirus disease 2019 (COVID-19) as reported in previous published systematic reviews.
UPDATED
CLINICAL CHARACTERISTICS
10/7/20
Leochico CFD, Espiritu AI, Ignacio SD, et al. | Front Neurol
Aim: To determine the challenges faced by telerehabilitation in the Philippines.
INFECTION CONTROL
10/7/20
Miller L, Bhattacharyya R, Miller AL | Medicine
Aim: To determine the mortality rate of hospitalized patients with Covid-19 in China and to identify factors that may potentially influence this rate.
CLINICAL CHARACTERISTICS
10/7/20
 | NSW Health COVID-19 Critical Intelligence Unit
10/7/20
Ferner RE, Aronson JK | Oxford COVID-19 Evidence Service
10/7/20
Setiati S, Harimurti K, Safitri ED, et al | Acta Med Indones
Aim: To systematically review all relevant studies related to the risk factors and laboratory test results associated with severe illness and mortality in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/7/20
Muacevic A, Adler JR | Cureus
Aim: To examine the association between smoking and mortality in COVID-19.
CLINICAL CHARACTERISTICS
10/7/20
Betancourt JA, Rosenberg MA, Zevallos A, et al. | Healthcare
Aim: To review the evidence on the impact of the COVID-19 pandemic on the provision of care through telemedicine across unique health service lines that include dermatology, oncology, obstetrics/gynecology, and mental health.
INFECTION CONTROL
10/7/20
Magill E, Siegel Z, Pike KM | Psychiatr Serv
Aim: To review the evidence on the anticipated mental health sequelae for frontline health workers and best practices to address those mental health needs.
MENTAL HEALTH
10/7/20
Luo L, Fu M, Li Y, et al. | Clin Cardiol
Aim: To assess the association between underlying comorbidities and acute cardiac injury and the severity or the prognosis in COVID?19 patients.
CLINICAL CHARACTERISTICS
10/7/20
 | NSW Health COVID-19 Critical Intelligence Unit
10/6/20
Yekeduz E, Utkan G, Urun Y | Eur J Cancer
Aim: To evaluate cancer treatment’s effect on the severity of COVID-19.
CLINICAL CHARACTERISTICS
10/6/20
Mandal A, Nandi S, Chhebbi M, et al. | Indian J Otolaryngol Head Neck Surg
Aim: To review the current guidelines and safety measures to be followed during tracheostomy in COVID-19 infected patients.
CLINICAL CHARACTERISTICS
10/6/20
Kamel AM, Sobhy M, Magdy N, et al. | Rev Med Virol
Aim: To investigate the association between AC and outcomes in hospitalized Covid?19 patients.
CLINICAL CHARACTERISTICS
10/6/20
Tu TM, Goh C, Tan YK, et al. | J Stroke Cerebrovasc Dis
Aim: To perform a systematic review of known cases of concomitant COVID-19 infection and CVT in the current literature.
CLINICAL CHARACTERISTICS
10/6/20
Olorunsaiye CZ, Yusuf KK, Reinhart K, et al. | Int J MCH AIDS
Aim: To review the evidence on the immunization landscape since the COVID-19 pandemic.
INFECTION CONTROL
10/6/20
Cheng W, Li Y, Cui L, et al. | Front Pharmacol
Aim: To evaluate the efficacy and safety of corticosteroid therapy in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/6/20
Sharma SK, Mishra M, Mudgal SK | J Educ Health Promot
Aim: To update the available most recent evidences on efficacy of cloth face masks in prevention of viral infection transmission.
10/6/20
Cheong KX | Curr Ophthalmol Rep
Aim: To summarise and discuss the current literature regarding ocular involvement of SARS-CoV-2 in COVID-19.
CLINICAL CHARACTERISTICS
10/6/20
Jena A, Singh AK, Kumar-M P, et al. | Dig Liver Dis
Aim: To identify the frequency and reasons for the disruption of care for IBD patients and attempted to identify regional differences in patterns of adherence to IBD therapies.
10/5/20
Meyerowitz-Katz G, Merone L | Int J Infect Dis
Aim: To review the evidence on infection-fatality rates for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/5/20
Noorimotlagh Z, Mirzaee SA, Jaafarzadeh N, et al. | Environ Sci Pollut Res Int
Aim: To collect all available studies concerning inactivation methods, environmental survival, and control and prevention strategies related to SARS-CoV-2. 
INFECTION CONTROL
10/5/20
Tlayjeh H, Mhish O, Enani M, et al. | J Infect Public Health
Aim: To systematically review the literature about the association between systemic corticosteroid therapy (CST) and outcomes of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/5/20
Moutchia J, Pokharel P, Kerri A, et al. | PLoS One
Aim: To assess clinical laboratory parameters which may serve as markers or predictors of severe or critical COVID-19.
UPDATED
DIAGNOSTICS
10/5/20
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