COVID-19 Evidence Reviews
as of 6/11/21
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6/09/2021
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Completed Reviews
 
= living review
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
latest update
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6/11/21
Harrison SL, Buckley BJR, Rivera-Caravaca JM, et al. | Eur Heart J Qual Care Clin Outcomes
Aim: To consolidate evidence to determine (i) the association between cardiovascular risk factors and health outcomes with coronavirus 2019 (COVID-19); and (ii) the impact of COVID-19 on cardiovascular health.
6/11/21
Flumignan RL, Tinôco JDS, Pascoal PI, et al. | Br J Surg
Aim: To assess the effects of prophylactic anticoagulants for people hospitalized with COVID-19.
6/11/21
Akbar M, Pranata R, Wibowo A, et al | Eur Rev Med Pharmacol Sci
Aim: To evaluate the association between the prealbumin and severity and mortality in COVID-19.
RECENTLY UPDATED
6/10/21
SeyedAlinaghi S, Mirzapour P, Dadras O, et al. | Eur J Med Res
Aim: To characterize the different variants of SARS-CoV-2 and explore the related morbidity and mortality.
6/10/21
Lewis A, Jain R, Frontera J, | J Neuroimaging
Aim: To evaluate cerebrospinal fluid (CSF) results from patients with coronavirus disease 2019 (COVID-19) who had neurological symptoms and had an MRI that showed (1) central nervous system (CNS) hyperintense lesions not attributed to ischemia and/or (2) leptomeningeal enhancement. 
6/10/21
Hughes MC, Liu Y, Baumbach A | Gerontol Geriatr Med
Aim: To examine the current literature on the impact of COVID-19 on the health and well-being of informal caregivers for people with dementia. 
RECENTLY UPDATED
6/10/21
Nakhlband A, Fakhari A, Azizi H | J Med Virol
Aim: To investigate the efficiency of interferon-alpha against COVID-19.
6/10/21
Al Mamun F, Hosen I, Misti JM, et al. | Psychol Res Behav Manag
Aim: To review the evidence on the prevalence and associated risk factors of Bangladeshi students’ mental health sufferings (ie, depression, anxiety, and stress).
6/10/21
Guimarães D, Pissarra R, Reis-Melo A, et al. | Int J Clin Pract
Aim: To analyze current literature and reported cases of MISC, concerning its clinical spectrum, complications associated, therapeutic strategies and distinguishing features of other clinical syndromes.
6/10/21
Zein AFMZ, Sulistiyana CS, Raffaello WM, et al. | Postgrad Med J
Aim: To evaluate the effect of sofosbuvir/daclatasvir (SOF/DCV) on mortality, the need for intensive care unit (ICU) admission or invasive mechanical ventilation (IMV) and clinical recovery in patients with COVID-19.
RECENTLY UPDATED
6/9/21
Asiimwe IG, Pushpakom S, Turner R, et al | Br J Clin Pharmacol
Aim: To continually evaluate the rapidly evolving evidence base on the role of cardiovascular drugs in COVID-19 clinical outcomes (susceptibility to infection, hospitalization, hospitalization length, disease severity, and all-cause mortality).
RECENTLY UPDATED
6/9/21
Rodríguez PG, Agapito BP, Rodríguez MSA, et al. | An Pediatr
Aim: To summarize a critical appraisal document of the available evidence on COVID-19, developed with a clinical practice guide format following GRADE methodology.
6/9/21
Abbas M, Zhu NJ, Mookerjee S, et al. | J Hosp Infect
Aim: To explore and describe the current literature in HOCI surveillance.
6/9/21
Amani B, Khanijahani A, Amani B | Sci Rep
Aim: To examine the efficacy and safety of HCQ in addition to standard of care (SOC) in COVID-19.
RECENTLY UPDATED
6/9/21
Liu DT, Philips KM, Speth MM, et al. | Otolaryngol Head Neck Surg
Aim: To summarize the current state of knowledge on portable high-efficiency particulate air (HEPA) purifiers' effectiveness in eliminating airborne SARS-CoV-2 from indoor environments.
6/9/21
Matli K, Farah R, Maalouf M, et al. | Open Heart
Aim: To highlight the role of thrombosis in COVID-19 and provide new insights on the use of antithrombotic therapy in its management. 
RECENTLY UPDATED
6/9/21
Moghadasi AN, Mirmosayyeb O, Barzegar M, et al. | Neurol Sci
Aim: To estimate the pooled prevalence of COVID-19 in patients with MS.
6/8/21
Nikoloski Z, Alqunaibet AM, Alfawaz RA, et al. | BMC Public Health
Aim: To systematize the available evidence on the link between non-communicable diseases and Covid-19.
6/8/21
Yang J, D'souza R, Kharrat A, et al. | Acta Obstet Gynecol Scand
Aim: To conduct a living systematic review and meta-analyses of studies reporting pregnancy and neonatal outcomes by comparing the pandemic and pre-pandemic periods.
RECENTLY UPDATED
6/8/21
Kurnianto A, Tugasworo D, Andhitara Y, et al. | Egypt J Neurol Psychiatr Neurosurg
Aim: To evaluate and summarize the scientific literature systematically to explore MT for AIS in the COVID-19 pandemic.
6/8/21
Mohan N, Fayyaz MA, Del Rio C, et al. | Egypt J Neurol Psychiatr Neurosurg
Aim: To evaluate and correlate the neuro-radiological and neurological manifestations in patients diagnosed with SARS-CoV2.To identify neuro-invasive pathways of COVID infection.
6/8/21
Sarkar S, Kannan S, Khanna P, et al. | Rev Med Virol
Aim: To explore the utility of RDW in the prognosis of COVID-19 patients.
RECENTLY UPDATED
6/8/21
Zugaj M, van Ditzhuijzen NS, Golebski K, et al. | Rhinology
Aim: To review the effects of the 7 known human coronaviruses on olfaction to determine if SARS-CoV-2 distinctly affects the olfactory system.
6/8/21
Wu KS, Lin PC, Chen YS, et al. | Ann Med
Aim: To investigate the association between statins and COVID-19 outcomes and, if possible, identify the subgroup population that benefits most from statin use.
6/8/21
Liang SB, Fang M, Liang CH, et al. | Complement Ther Med
Aim: To evaluate the therapeutic effects and safety of oral CPM for COVID-19.
6/7/21
Singh H, Maurya RK, Sharma P, et al. | Int Orthod
Aim: To provide an insight into the prevailing and emerging evidence informing potential risks related to splatter and AGPs, and risk mitigation strategies employed for reducing the potential risk of SARS-CoV-2 transmission from dental bioaerosols.
6/7/21
Liu X, Wang H, Shi S, et al. | Postgrad Med J
Aim: To evaluate the association between IL-6 and severe disease and mortality in COVID-19 disease.
RECENTLY UPDATED
6/7/21
Guerrero JI, Barragan LA, Martinez JD, et al. | BMC Infect Dis
Aim: To describe the features of the central and peripheral nervous system involvement by COVID-19 in terms of pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings.
RECENTLY UPDATED
6/7/21
Nascimento I, O Mathuna DP, von Groote TC, et al. | BMC Infect Med
Aim: To collate and summarize all published systematic reviews on the coronavirus disease (COVID-19).
RECENTLY UPDATED
6/7/21
Ruta F, Dal Mas F, Biancuzzi H, et al. | Prof Inferm
Aim: To analyze the literature relating to the impact on the mental health of nurses engaged in the management and care of Covid-19 patients.
6/7/21
Messina A, Sanfilippo F, Milani A, et al. | J Crit Care
Aim: To summarise the current knowledge regarding cardiac dysfunction in COVID-19 as assessed by echocardiography, both in ICU and non-ICU subjects.
RECENTLY UPDATED
6/7/21
Sterina E, Hermida AP, Gerberi DJ, et al. | Clin Gerontol
Aim: To examine post-traumatic stress, depression, anxiety, and well-being in older adults under quarantine.
6/7/21
Alkatout I, Biebl M, Momenimovahed Z, et al. | Front Oncol
Aim: To investigate the impact of COVID-19 on cancer screening.
6/7/21
Zuin M, Rigatelli G, Bilato C, et al. | Acta Cardiol
Aim: To evaluate the pooled incidence of acute HF as a cardiac complication of COVID-19 disease and to estimate the related mortality risk in these patients.
6/7/21
Seidu S, Kunutsor SK, Cos X, et al. | Prim Care Diabetes
Aim: To assess the indirect impact of the COVID-19 pandemic on hospitalisations for cardiovascular diseases and their management.
RECENTLY UPDATED
6/7/21
Siracusa L, Cascio A, Giordano S, et al. | Ital J Pediatr
Aim: To describe clinical characteristics, laboratory tests, radiological data and outcome of pediatric cases with SARS-CoV-2 infection complicated by neurological involvement.
6/7/21
Rogers JP, Watson CJ, Badenoch J, et al. | J Neurol Neurosurg Psychiatry
Aim: To describe the characteristics of the early literature and estimate point prevalences for neurological and neuropsychiatric manifestations.
RECENTLY UPDATED
6/7/21
Salah G, Ahmed A, Hassanain O, et al. | Nutr Cancer
Aim: To understand the role of nutrition in cancer patients during Corvid 19 era.
6/7/21
Subali AD, Wiyono L | Pathog Glob Health
Aim: To review the evidence on RT-LAMP application for rapid identification of SARS-CoV-2 infection compared to the RT-PCR assay.
6/7/21
Ao G, Wang Y, Qi X, et al. | Transplant Rev
Aim: To investigate the association between severe or fatal COVID-19 and SOT.
RECENTLY UPDATED
6/7/21
Atieh MA, Guirguis M, Alsabeeha NHM, et al. | Oral Dis
Aim: To systematically evaluate the current literature on the use of saliva test for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and carry out a meta-analysis to determine its diagnostic accuracy.
6/7/21
Chong WH, Saha BK, Hu K, et al. | Heart Lung
Aim: To describe the incidence, clinical characteristics, and outcomes of COVID-19-related pneumothorax.
6/7/21
Elsayed HH, Hassaballa AS, Ahmed TA, et al. | PLoS One
Aim: To review the evidence on IMV for COVID-associated ARDS to study its outcome among different countries.
RECENTLY UPDATED
6/7/21
Mai V, Tan BK, Mainbourg S, et al. | Vascul Pharmacol
Aim: To compare the rate of VTE between COVID-19 and non-COVID-19 cohorts with similar disease severity.
6/3/21
Kao Y, Lin K | Diagnostics
Aim: To use computerized tomography (CT)-based radiomics models to differentiate COVID-19 pneumonia from other viral pneumonia infections.
DIAGNOSTICS
6/3/21
 | Health Information and Quality Authority
Aim: To review the international policies and guidelines relating to healthcare personnel who do not avail of COVID-19 vaccination.
6/3/21
Reyes FM, Hache-Marliere M, Karamanis D, et al. | J Clin Med
Aim: To explore the association of COPD and asthma with in-hospital mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
6/3/21
Jimenez-Cebrian AM, Castro-Mendez A, Garcia-Podadera B, et a;/ | J Clin Med
Aim: To analyze and synthesize the published reviews on manifestations of COVID-19 at the foot level. 
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/3/21
Arfaras-Melainis A, Tzoumas A, Kokkinidis DG, et al. | J Cardiovasc Dev Dis
Aim: To assess the effect of hydroxychloroquine with or without the addition of azithromycin on the QTc of hospitalized patients with COVID-19.
CANDIDATE THERAPEUTICS
6/3/21
Pormohammad A, Zarei M, Ghorbani S, et al. | Vaccines
Aim: To review the evidence on the clinical features of COVID-19 vaccines to provide a better estimate of their efficacy, side effects and immunogenicity.
INFECTION CONTROL
6/3/21
Leyser M, Marques FJP, do Nascimento OJM | Rev Paul Pediatr
Aim: To perform a systematic literature review to analyze existing data on the neurological effects of coronavirus on newborns.
CLINICAL CHARACTERISTICS
6/3/21
Orozco MFS, Nino-Martinez N, Martinez-Castanon GA, et al. | Medicina
Aim: To summarize the current data about the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its entry factors in oral tissues and cells. 
INFECTION CONTROL
6/3/21
Bellotti L, Zaniboni S, Balducci C, et al. | Int J Environ Res Public Health
Aim: To analyze the effects that the COVID-19 pandemic had on employment and work-related aspects across different age groups.
INFECTION CONTROL
6/3/21
Santana MAC, Cano JAA, Kanan AD, et al. | Medicina
Aim: To contrast the existing evidence regarding the relationship between periodontal disease (PD) and diabetes mellitus (DM) with the possibly increased risk of SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
6/3/21
Kordsmeyer A, Mojtahedzadeh N, Heidrich J, et al. | Int J Environ Res Public Health
Aim: To provide an overview of outbreaks of SARS-CoV-2 on board of cruise, navy or cargo ships, to identify relevant outbreak management techniques, related problems and to derive recommendations for prevention. 
INFECTION CONTROL
6/3/21
Wang R, Liu M, Liu J | Vaccines
Aim: To assess the association between influenza vaccination and SARS-CoV-2 infection and clinical outcomes.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/3/21
Khan DSA, Pirzada AN, Ali A, et al. | Int J Environ Res Public Health
Aim: To investigate the differences in clinical presentation, management, and prognosis of COVID-19 infection in pregnant and non-pregnant women.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/3/21
Chaabane S, Doraiswamy S, Chaabna K, et al. | Children
Aim: To synthesize available data on the impact of school closure during the coronavirus disease 2019 (COVID-19) pandemic on child and adolescent health globally. 
MENTAL HEALTH
6/3/21
Ippolito M, Misseri G, Catalisano G, et al. | Antibiotics
Aim: To estimate the pooled occurrence of ventilator-associated pneumonia (VAP) among patients admitted to an intensive care unit with COVID-19 and mortality of those who developed VAP.
CLINICAL CHARACTERISTICS
6/3/21
Stroehlein JK, Wallqvist J, Iannizzi C, et al.  | Cochrane Database Syst Rev
Aim: To assess whether vitamin D supplementation is effective and safe for the treatment of COVID?19 in comparison to an active comparator, placebo, or standard of care alone, and to maintain the currency of the evidence, using a living systematic review approach.
RECENTLY UPDATED
CANDIDATE THERAPEUTICS
6/2/21
Franchini M, Cruciani M, Mengoli C, et al. | Blood Transfus
Aim: To assess the relationship between the ABO blood group and the occurrence and severity of COVID-19.
CLINICAL CHARACTERISTICS
6/2/21
Wilt T, Kaka AS, MacDonald R, et al. | VA Evidence Synthesis Program
Aim: To assess the clinical effectiveness and harms of remdesivir in hospitalized adults with COVID-19.
RECENTLY UPDATED
VA ESP
6/2/21
Patnaik N, Bhatia V, Mishra KG, et al. | J Family Med Prim Care
Aim: To analyse symptoms of pregnant women affected with COVID-19.
6/2/21
Wang MX, Gwee SXW, Pang J | Nutrients
Aim: To systematically assess the associations between micronutrient supplementation or deficiency, with novel coronavirus incidence and disease severity.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/2/21
Schulte EC, Hauer L, Kunz AB, et al. | Eur J Neurol
Aim: To review cases of ATM described in the context of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection.
CLINICAL CHARACTERISTICS
6/1/21
Hempel S, Burke RV, Hochman M, et al. | J Clin Epidemiol
Aim: To review evidence-based approaches for evaluation of strategies for policymakers.
6/1/21
Grove A, Osokogu O, Al-Khudairy L, et al. | BMJ Open
Aim: To systemically review and critically appraise published studies of the association between vitamin D supplementation or serum vitamin D level and susceptibility to SARS-CoV-2 infection or COVID-19, including clinical course, morbidity and mortality outcomes.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/1/21
Dumitrascu F, Branje KE, Hladkowicz ES, et al. | J Am Geriatr Soc
Aim: To identify, describe, and synthesize studies reporting the association of frailty with outcomes (informed by the Institute for Healthcare Improvement's Triple Aim [health, resource use, and experience]) in individuals with COVID-19.
CLINICAL CHARACTERISTICS
6/1/21
Carroll E, Melmed KR, Frontera J, et al. | Seizure
Aim: To review the CSF results in published case reports and case series of patients with COVID-19 who had seizures to evaluate for evidence of viral neuroinvasion.
CLINICAL CHARACTERISTICS
6/1/21
Manoharan L, Olliaro P, Horby PW, et al. | Trials
Aim: To critically appraise significant design features and alignment of study populations to clinical and public health uses, and describe candidate chemoprophylactic agents.
INFECTION CONTROL
6/1/21
da Silva RP, Goncalves JIB, Zanin RF, et al. | Front Immunol
Aim: To summarize the available evidence of the association of plasma protein levels of type I IFN with the severity of COVID-19.
CLINICAL CHARACTERISTICS
6/1/21
Seth T, Elavarasi A, Sahoo RK, et al. | Natl Med J India
Aim: To synthesize the available data on CP therapy for treatment of Covid-19 to study the efficacy and safety outcomes.
CANDIDATE THERAPEUTICS
6/1/21
Ayouni I, Maatoug J, Dhouib W, et al.  | BMC Public Health
Aim: To evaluate the implemented public health interventions to control the spread of the outbreak of COVID-19.
RECENTLY UPDATED
INFECTION CONTROL
6/1/21
Prasad M, Elavarasi A, Madan K, et al. | Natl Med J India
Aim: To review the evidence on the use of antivirals for Covid-19.
CANDIDATE THERAPEUTICS
6/1/21
Shetty RM, Namachivayam AK | Indian J Crit Care Med
Aim: To review the evidence for the benefit of chloroquine/hydroxychloroquine in the treatment of patients with COVID-19.
CANDIDATE THERAPEUTICS
6/1/21
Manabe T, Kambayashi D, Akatsu H, et al. | BMC Infect Dis
Aim: To review systematically on the application of favipiravir for patients with COVID-19 to identify empirical evidence of its efficacy.
CANDIDATE THERAPEUTICS
6/1/21
Bolia R, Goel AD, Badkur M, et al. | J Trop Pediatr
Aim: To determine the GI manifestations of pediatric COVID-19 and to evaluate their role as risk factors for a severe clinical course.
CLINICAL CHARACTERISTICS
6/1/21
Lee Y, Lui LMW, Chen-Li D, et al. | J Affect Disord
Aim: To evaluate the impact of the COVID-19 pandemic and government response on measures of depressive symptom presence and severity based on published studies.
RECENTLY UPDATED
MENTAL HEALTH
6/1/21
Kaur H, Thakur JS, Paika R, et al. | Asian Pac J Cancer Prev
Aim: To explore the prevalence of comorbidities among cancer patients with SARS CoV-2 infection and their impact on mortality.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/1/21
Muehlschlegel P, Parkinson E, Chan RYL, et al. | J Glob Health
Aim: To comprehensively evaluate biopsychosocial consequences after lockdown measures are lifted and identify strategies to successfully negotiate the transition out of COVID-19 related lockdowns.
RECENTLY UPDATED
MENTAL HEALTH
6/1/21
Amani B, Khanijahani A, Amani B, et al. | J Pharm Pharm Sci
Aim: To provide the latest evidence on the efficacy and safety of lopinavir/ritonavir compared to other treatment options for COVID-19.
RECENTLY UPDATED
CANDIDATE THERAPEUTICS
6/1/21
Radovanovic D, Coppola S, Franceschi E, et al. | J Crit Care
Aim: To analyse mortality and intubation rates in COVID-19 patients treated with NIV/CPAP.
CANDIDATE THERAPEUTICS
6/1/21
Tagliamento M, Agostinetto E, Bruzzone M, et al. | Crit Rev Oncol Hematol
Aim: To estimate the mortality in patients with cancer and SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
6/1/21
Singh S, Verma N, Kanaujia R, et al. | Mycoses
Aim: To synthesize the results of primary studies on CAPA and to provide pooled mortality estimators of in-hospital mortality of the disease and potential predictors of outcome.
CLINICAL CHARACTERISTICS
6/1/21
Almazroa A, Alamri S, Alabdulkader B, et al. | Int Health
Aim: To review the evidence on ocular transmission and manifestations of SARS-CoV-2.
CLINICAL CHARACTERISTICS
6/1/21
Bekele F, Machessa DF, Sefera B | Ann Med Surg
Aim: To summarize the prevalence and associated factors of the psychological impact of COVID-19 among the health care workers (HCWs), patients and communities in Ethiopia.
MENTAL HEALTH
6/1/21
Zawawi A, Naser AY, Alwafi H, et al. | Front Immunol
Aim: To evaluate the inflammatory cytokines profile associated with severe human coronavirus diseases, including three stains: MERS-CoV, SARS-CoV SARS-CoV-2, in severe patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/1/21
O Murchu E, Byrne P, Carty PG, et al. | Rev Med Virol
Aim: To evaluate the risk and relative risk of SARS-CoV-2 reinfection over time, comparing previously infected individuals to those without evidence of prior infection.
CLINICAL CHARACTERISTICS
6/1/21
Tasavon Gholamhoseini M, Yazdi-Feyzabadi V, Goudarzi R, et al. | J Pharm Pharm Sci
Aim: To assess the safety and efficacy of remdesivir in adult patients with COVID-19.
CANDIDATE THERAPEUTICS
6/1/21
Hou H, Li Y, Zhang P, et al. | Nicotine Tob Res
Aim: To explore the association between smoking and mortality of coronavirus disease 2019 (COVID-19) patients utilizing a quantitative meta-analysis on the basis of adjusted effect estimates.
CLINICAL CHARACTERISTICS
6/1/21
Kabrah SM, Kabrah AM, Flemban AF, et al. | Transfus Apher Sci
Aim: To evaluate the existing evidence on the susceptibility of the ABO blood group to COVID-19 infection.
CLINICAL CHARACTERISTICS
6/1/21
Peters A, Palomo R, Ney H, et al. | Antimicrob Resist Infect Control
Aim: To review the various methods for decontamination and the potential issues to be taken into account when deciding to reuse masks. 
INFECTION CONTROL
6/1/21
Melesse DY, Chekol WB | Clin Nutr Open Sci
Aim: To review the evidence on the management of critically ill patients with COVID-19 in ICU in resource limiting settings.
CANDIDATE THERAPEUTICS
5/28/21
Nasserie T, Hittle M, Goodman SN | JAMA Netw Open
Aim: To conduct a systematic review of studies examining the frequency and variety of persistent symptoms after COVID-19 infection.
CLINICAL CHARACTERISTICS
5/28/21
Staibano P, Levin M, McHugh T, et al. | JAMA Otolaryngol Head Neck Surg
Aim: To evaluate the association of tracheostomy with COVID-19 patient outcomes and the risk of SARS-CoV-2 transmission among health care professionals (HCPs).
UPDATED
INFECTION CONTROL
5/28/21
Iqbal FM, Lam K, Sounderajah V, et al. | EClinicalMedicine
Aim: To characterise the clinical features between acute and chronic post-COVID syndrome.
UPDATED
CLINICAL CHARACTERISTICS
5/28/21
Karam M, Althuwaikh S, Alazemi M, et al. | JRSM Open
Aim: To compare the performance of chest computed tomography (CT) scan versus reverse transcription polymerase chain reaction (RT-PCR) as the reference standard in the initial diagnostic assessment of coronavirus disease 2019 (COVID-19) patients.
DIAGNOSTICS
5/28/21
Kastora S, Kounidas G, Perrott S, et al. | EClinicalMedicine
Aim: To quantify the impact of clinical frailty scale (CFS) by increasing severity of frailty and to identify other personal prognostic factors associated with increased mortality from COVID-19.
CLINICAL CHARACTERISTICS
5/28/21
Arienti C, Lazzarini S, Pollini E, et al. | J Rehabil Med
Aim: To assess the effectiveness of rehabilitation interventions in adults with multiple organ dysfunction syndrome.
CANDIDATE THERAPEUTICS
5/28/21
Panda S, Nanda R, Tripathy PK, et al. | J Family Med Prim Care
Aim: To summarize the alteration in the immunological and inflammatory markers of COVID-19 cases reported in currently available observational studies and their associations with the severity of disease process.
CLINICAL CHARACTERISTICS
5/28/21
Fahmy OH, Daas FM, Salunkhe V, et al. | Crit Care Explor
Aim: To retrieve and report the findings of postmortem studies including the histopathologic data of deceased coronavirus disease 2019 patients and to review the manifestations of coronavirus disease 2019–associated thrombotic pathologies reported in the recent literature.
CLINICAL CHARACTERISTICS
5/28/21
Kaur U, Chakrabarti SS, Patel TK | Ther Adv Drug Saf
Aim: To provide a pooled estimate of the effect of RAAS blockers on COVID-19 outcomes.
CANDIDATE THERAPEUTICS
5/28/21
Ali ST, Yeung A, Shan S, et al. | Clin Infect Dis
Aim: To summarize the existing evidence on serial interval distributions and delays in case isolation for COVID-19.
INFECTION CONTROL
5/28/21
Sahilu T, Sheleme T, Melaku T | Interdiscip Perspect Infect Dis
Aim: To summarize the current evidence of the severity and mortality associated with steroid therapy for patients with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
5/28/21
de Sousa Neto AR, de Carvalho ARB, de Oliveira EMN, et al. | Rev Gaucha Enferm
Aim: To identify symptoms of COVID-19 in adults in the scientific literature.
CLINICAL CHARACTERISTICS
5/28/21
Hassanipour S, Arab-Zozani M, Amani B, et al. | Sci Rep
Aim: To investigate the efficacy and safety of Favipiravir in treatment of COVID-19 patients.
CANDIDATE THERAPEUTICS
5/24/21
Vanderlind WM, Rabinovitz BB, Miao IY, et al. | Curr Opin Psychiatry
Aim: To synthesize available literature on psychiatric and cognitive characteristics of community-dwelling survivors of COVID-19 infection.
MENTAL HEALTH
5/24/21
Hooper JJ, Saulsman L, Hall T, et al. | BMJ Open
Aim: To identify and summarise recent early psychological intervention programmes that were administered to prevent or minimise psychological harm in frontline responders.
MENTAL HEALTH
5/24/21
Massarvva T | Epidemiol Health
Aim: To systematically review up-to-date studies reporting on the clinical outcomes of COVID-19 amongst HIV patients.
CLINICAL CHARACTERISTICS
5/24/21
Barzegar M, Mirmosayyeb O, Gajarzadeh M, et al. | Neurol Neuroimmunol Neuroinflamm
Aim: To systematically review the literature on COVID-19 in patients with multiple sclerosis (MS).
CLINICAL CHARACTERISTICS
5/24/21
Shah S, Akhade K, Ganguly S, et al. | J Family Med Prim Care
Aim: To summarize the major patterns of dermatological manifestations associated with SARS-CoV-2 virus infection.
CLINICAL CHARACTERISTICS
5/24/21
Garcia-Azorin D, Seeher KM, Newton CR, et al. | J Neurol
Aim: To evaluate the particular impact on neurological services.
INFECTION CONTROL
5/24/21
Chmielewska B, Barratt I, Townsend R, et al. | Lancet Glob Health
Aim: To assess the collateral effects on maternal, fetal, and neonatal outcomes of the global COVID-19 pandemic.
CLINICAL CHARACTERISTICS
5/24/21
Mangkuliguna G, Glendardi G, Susanto N, et al. | Tuberc Respir Dis
Aim: To investigate the efficacy and safety of Azithromycin in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/24/21
Patel TK, Patel PB, Barvaliya M, et al. | J Infect Public Health
Aim: To evaluate a pooled effect of lopinavir-ritonavir on mortality, virological cure, radiological improvement and safety profile in COVID-19 patients.
CANDIDATE THERAPEUTICS
5/24/21
SeyedAlinaghi S, Mehrtak M, MohsseniPour M, et al. | Eur J Med Res
Aim: To investigate the available evidence for the genetic susceptibility to COVID-19.
CLINICAL CHARACTERISTICS
5/24/21
Salamanna F, Veronesi F, Martini L, et al. | Front Med
Aim: To assess the current evidence on the long-term symptoms in COVID-19 patients.
CLINICAL CHARACTERISTICS
5/24/21
Abate SM, Chekole YA, Estifanos MB, et al. | Clin Nutr ESPEN
Aim: To investigate the prevalence and outcome of malnutrition among patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/24/21
Mathew HR, Choi MY, Parkins MD, et al. | BMC Pulm Med
Aim: To systematically survey published accounts of COVID-19 in CF and determine if individuals with CF are disproportionally affected by SARS-CoV-2 and development of COVID-19.
CLINICAL CHARACTERISTICS
5/24/21
Li W, Zhang H, Zhang C, et al. | Front Psychol
Aim: To review the evidence on the prevalence of different psychological states during the early stage of the COVID-19 epidemic in China.
UPDATED
MENTAL HEALTH
5/24/21
Snow TAC, Saleem N, Ambler G, et al. | Intensive Care Med
Aim: To ascertain the benefit of IL-6 blockade with tocilizumab for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
5/21/21
Singhal S, Kumar P, Singh S, et al. | BMC Geriatr
Aim: To review the evidence on the clinical characteristics of older COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/21/21
Piechotta V, Iannizzi C, Chai KL, et al. | Cochrane Database Syst Rev
Aim: To assess whether convalescent plasma or hyperimmune immunoglobulin transfusion is effective and safe in the treatment of people with COVID?19.
UPDATED
CANDIDATE THERAPEUTICS
5/21/21
Pulakurthi YS, Pederson JM, Saravu K, et al. | Medicine
Aim: To investigate the clinical outcomes associated with corticosteroid treatment of COVID-19.
CANDIDATE THERAPEUTICS
5/21/21
O'Leary N, Kingston L, Griffin A, et al. | Scand J Public Health
Aim: To document the healthcare policies developed during the initial wave of widespread COVID-19 transmission in Ireland. 
5/21/21
Bzeizi K, Abdulia M, Mohammed N, et al. | Sci Rep
Aim: To assess the available evidence on the clinical effects of SARS-CoV-2 on liver function laboratory tests and coagulation profile in affected individuals. 
UPDATED
CLINICAL CHARACTERISTICS
5/21/21
Xiong X, Chi J, Gao Q | Thromb J
Aim: To determine the prevalence and risk factors of thrombotic events on COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/21/21
Bin Nafisah SA, Mzahim BY, Aleid BS, et al. | Ann Thorac Med
Aim: To assess the occurrence of disease transmission to HCPs from the performance aerosol-generating procedures (AGPs).
INFECTION CONTROL
5/21/21
Avni T, Leibovici L, Cohen I, et al. | QJM
Aim: To evaluate whether IL-6 inhibitor tocilizumab (TCZ) reduces mortality among hospitalized COVID-19 patients.
CANDIDATE THERAPEUTICS
5/20/21
Wang J, Kaperak C, Sato T, et al. | J Investig Med
Aim: To identify cases infected with different genetic strains of SARS-CoV-2 confirmed by polymerase-chain reaction and viral genome sequencing.
UPDATED
DIAGNOSTICS
5/20/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on COVID-19 vaccination before elective surgery, including any recommendations regarding the timing of vaccination.
5/20/21
Hampson G, Stone M, Lindsay JR, et al. | Calcif Tissue Int
Aim: To provide information on how the COVID-19 pandemic has impacted the diagnosis and management of osteoporosis.
5/20/21
Alcock H, Moppett EA, Moppett IK | Bone Jt Open
Aim: To understand the impact of coexistent hip fracture and SARS-CoV-2 for informed decision-making at patient and service levels.
CLINICAL CHARACTERISTICS
5/20/21
Manoharan L, Cattrall JW, Harris C, et al. | PLoS One
Aim: To summarize the early literature on clinical characteristics of patients admitted to hospital, and evaluates the quality of evidence produced during the initial stages of the pandemic.
CLINICAL CHARACTERISTICS
5/20/21
Minozzi S, Saulle R, Amato L, et al. | Recenti Prog Med
Aim: To summarize the data of a systematic review on the impact of the 2020 school closure and social distances measures implemented in response to COVID-19 pandemic on youths' physical health and psychological wellbeing. 
MENTAL HEALTH
5/20/21
Minozzi S, Saulle R, Amato L, et al. | Recenti Prog Med
Aim: To summarize the most relevant data of a systematic review on the impact of the 2020 school closure and social distances measures implemented in response to COVID-19 pandemic on youths physical health and psychological wellbeing.
MENTAL HEALTH
5/20/21
Saulle R, Minozzi S, Amato L, et al. | Recenti Prog Med
Aim: To summarize the most relevant data from a literature systematic review on the impact on youths' physical health of the 2020 school closure and social distances measures implemented in response to COVID-19 pandemic.
5/20/21
Haghpanah A, Masjedi F, Salehipour M, et al. | Prostate Cancer Prostatic Dis
Aim: To explore the potential mechanisms of SARS-CoV-2 in targeting the prostate gland, leading to exacerbation of benign prostatic hyperplasia (BPH) symptoms and greater risks of BPH complications such as acute urinary retention.
CLINICAL CHARACTERISTICS
5/20/21
Pannone G, Caponio VCA, De Stefano IS, et al. | Infect Agent Cancer
Aim: To summarize lung histopathological characteristics of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/20/21
Ishfaq A, Farooq SMY, Goraya A, et al. | Eur J Radiol Open
Aim: To identify the role of High-Resolution Computed Tomography chest and summarize characteristics of chest CT imaging for the diagnosis and evaluation of SARS-CoV-2 patients.
DIAGNOSTICS
5/20/21
Chen C, Hu F, Wei J, et al. | Leukemia
Aim: To determine safety and efficacy of tocilizumab in persons with coronavirus disease-2019 (COVID-19).
CANDIDATE THERAPEUTICS
5/20/21
Dhar D, Dey T, Samim MM, et al. | Pediatr Res
Aim: To review the evidence on the demographic profile, clinical characteristics, complications, management, and prognosis of MIS-C associated with COVID-19.
CLINICAL CHARACTERISTICS
5/20/21
Wei Q, Lin H, Wei R, et al. | Infect Dis Poverty
Aim: To review the evidence on tocilizumab treatment for COVID-19 patients.
CANDIDATE THERAPEUTICS
5/19/21
Barkas F, Ntekouan SF, Kosmidou M, et al. | Rheumatology
Aim: To assess the efficacy and safety of anakinra in adult hospitalized non-intubated patients with COVID-19.
CANDIDATE THERAPEUTICS
5/19/21
Campbell H, Wood AC | Curr Nutr Rep
Aim: To examine the evidence that the dietary quality of children changed between the period preceding the COVID-19 pandemic and the first year during the pandemic.
5/19/21
Scheiner NS, Smith AK, Wohlleber M, et al. | J Acad Consult Liaison Psychiatry
Aim: To review the extant literature describing catatonia in the setting of COVID-19 disease and highlight commonalities among the cases.
CLINICAL CHARACTERISTICS
5/19/21
Azab MA, Azzam AY | Brain Disord
Aim: To perform a meta-analysis of the available published data concerning the management of glioma patients in the published literature from the beginning of the pandemic to the end of 2020 concerning the number of operated surgeries, postoperative complications, and mortality outcomes.
CLINICAL CHARACTERISTICS
5/19/21
Quesada JA, Lopez-Pineda A, Gil-Guillen VF, et al. | Rev Clin Esp
Aim: To provide a more accurate estimate of the incubation period of COVID-19.
CLINICAL CHARACTERISTICS
5/19/21
Bekele F, Hajure M | SAGE Open Med
Aim: To summarize the magnitudes and determinants of the psychological impact of coronavirus among health care professionals.
MENTAL HEALTH
5/17/21
Bircakova B, Bruha R, Lambert L, et al. | Scand J Gastroenterol
Aim: To review clinical and laboratory findings in patients with SARS-Cov-2 (COVID-19) related acute pancreatitis.
CLINICAL CHARACTERISTICS
5/17/21
Cardwell K, O'Neill SM, Tyner B, et al. | Rev Med Virol
Aim: To identify measures available to support those in isolation or quarantine during the coronavirus disease 2019 (Covid-19) pandemic, and determine their effectiveness in improving adherence to these recommendations and or reducing transmission. 
INFECTION CONTROL
5/17/21
Hernandez-Perez A, Garcia-Gomez L, Rodriguez-Llamazares S, et al. | Salud Publica Mex
Aim: To describe the possible risks associated to smoking in the spread and complications of Covid-19, emphasizing in the benefits of quitting smoking.
CLINICAL CHARACTERISTICS
5/17/21
 | CADTH
Aim: To review the evidence on the availability, accuracy, safety, cost, and other considerations for using self-administered screening tests at home for severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2.
5/17/21
McDonald I, Murray SM, Reynolds CJ, et al. | NPJ Vaccines
Aim: To evaluate pertinent SARS-CoV-1, MERS-CoV and SARS-CoV-2 studies in humans and NHP.
INFECTION CONTROL
5/17/21
Gebreheat G, Teame H | J Multidiscip Healthc
Aim: To identify the main ethical challenges faced by nurses during COVID-19 pandemic.
5/17/21
Nochaiwong S, Ruengorn C, Thavorn K, et al. | Sci Rep
Aim: To provide a contemporary global prevalence of mental health issues among the general population amid the coronavirus disease-2019 (COVID-19) pandemic. 
UPDATED
MENTAL HEALTH
5/17/21
Lei H, Yang Y, Zhou W, et al. | Lung Cancer
Aim: To provide precise estimates of the mortality rate of COVID-19 patients with lung cancer and other tumors.
UPDATED
5/17/21
Shao SC, Lai CC, Chen YH, et al. | Age Aging
Aim: To summarize the evidence on prevalence, incidence and mortality of delirium in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/17/21
El-Menyar A, Mekkodathil A, Asim M, et al. | Sci Prog
Aim: To explore the standards for research conduction, publications and retraction of articles related to COVID-19 pharmacotherapy research during the pandemic.
5/17/21
Wingert A, Pillay J, Gates M, et al. | BMJ Open
Aim: To determine the magnitude of association between potential risk factors and severity of COVID-19, to inform vaccine prioritisation in Canada.
CLINICAL CHARACTERISTICS
5/17/21
Severo Bem Junior L, do Rego Aquino PL, Nunes Rabelo N, et al. | J Neurol Res
Aim: To reveal the current knowledge regarding CNS manifestation in SARS-CoV-2. 
CLINICAL CHARACTERISTICS
5/17/21
Mitra S, Ling RR, Yang IX, et al. | Ann Acad Med Singap
Aim: To review the evidence on COVID-19-induced coagulopathy.
CLINICAL CHARACTERISTICS
5/14/21
Biswas M, Most SKK | Sci Rep
Aim: To assess aggregated risk by investigating the association of ACEIs/ARBs users against non-users of ACEIs/ARBs with the risk of mortality or severe clinical manifestations or magnitude of SARS-CoV-2 test positivity in COVID-19 patients.
CLINICAL CHARACTERISTICS
5/14/21
Soeroto AY, Purwiga A, Pranggono EH, et al. | Asian Pac J Allergy Immunol
Aim: To investigate the association between asthma and composite poor outcome in patients with coronavirus disease (COVID-19).
CLINICAL CHARACTERISTICS
5/14/21
Wu T, Yu P, Li Y, et al. | J Asthma
Aim: To analyze the association between COVID-19 and asthma.
CLINICAL CHARACTERISTICS
5/14/21
Antwi HA, Zhou L, Xu X, et al. | Healthcare
Aim: To examine the extent to which companies are able to balance their business interest with social interest through health-related CSR and how knowledge of them can help explain the potential impact of COVID-19.
5/14/21
Munir MA, Tandiabang PA, Setyawati T, et al. | Transfus Clin Biol
Aim: To analyze the bioethical issues surrounding the potential use and study of convalescent plasma therapy in COVID-19.
CANDIDATE THERAPEUTICS
5/14/21
Lim KH, Soong F, Low YF, et al. | J Clin Virol
Aim: To determine the clinical manifestations of neonatal COVID-19 and outcomes based on severity groups. 
CLINICAL CHARACTERISTICS
5/14/21
De Crescenzo F, Amato L, Cruciani F, et al. | Front Pharmacol
Aim: To assess the comparative efficacy and safety of pharmacological interventions for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
5/14/21
Mourmouris P, Tzelves L, Roidi C, et al. | Osong Public Health Res Perspect
Aim: To identify the potential and definite sources of transmission of coronavirus disease 2019 (COVID-19).
INFECTION CONTROL
5/14/21
Kwee RM, Adams HJA, Kwee TC | Radiol Cardiothorac Imaging
Aim: To determine the diagnostic performance of the COVID-19 Reporting and Data System (CO-RADS) and the Radiological Society of North America (RSNA) categorizations in patients with clinically suspected coronavirus disease 2019 (COVID-19) infection.
DIAGNOSTICS
5/14/21
Zhan H, Chen H, Liu C, et al. | Clin Appl Thromb Hermost
Aim: To assess the predictive value of D-dimer for the severity, mortality and incidence of venous thromboembolism (VTE) events in COVID-19 patients.
DIAGNOSTICS
5/14/21
Khodeir MM, Shabana HA, Alkhamiss AS, et al. | J Infect Public Health
Aim: To review different biomarkers to systematically analyze these values to evaluate whether are they are correlated with the severity of COVID-19 disease and so their ability to be a predictor for progression.
CLINICAL CHARACTERISTICS
5/14/21
Siow I, Lee KS, Zhang JJY, et al. | Eur J Neurol
Aim: To describe the incidence, clinical course and outcomes of patients who suffer from encephalitis as a complication of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/14/21
Chambergo-Michilot D, Barros-Sevillano S, Rivera-Torrejon O, et al. | Eur J Neurol
Aim: To systematically review the factors associated with COVID-19 in people with PD.
UPDATED
CLINICAL CHARACTERISTICS
5/14/21
Heath L, Carey M, Lowney AC, et al.  | Palliat Med
Aim: To determine the dose ranges of pharmacological interventions commonly used to manage symptoms in adult patients dying of COVID-19, establish how effectiveness of these interventions was measured, and whether the pharmacological interventions were effective.
UPDATED
CANDIDATE THERAPEUTICS
5/14/21
Paternoster G, Bertini P, Innelli P, et al. | J Cardiothorac Vasc Anesth
Aim: To describe the features of right ventricular impairment and pulmonary hypertension in coronavirus disease (COVID-19) and assess their effect on mortality.
UPDATED
CLINICAL CHARACTERISTICS
5/14/21
James PT, Ali Z, Armitage AE, et al. | J Nutr
Aim: To review the latest evidence on how malnutrition across all its forms (under- and overnutrition and micronutrient status) may influence both susceptibility to, and progression of, COVID-19.
CLINICAL CHARACTERISTICS
5/13/21
Nobari NN, Seirafianpour F, Dodangeh M, et al. | Exp Dermatol
Aim: To collect the mucocutaneous histopathologic data of COVID-19 patients for future investigations and interpretations. 
CANDIDATE THERAPEUTICS
5/13/21
Kang S, Gong X, Yuan Y | Epidemiol Infect
Aim: To systematically assess the association between smoking and cardiovascular disease and disease progression among novel coronavirus pneumonia (COVID-19) cases.
UPDATED
CLINICAL CHARACTERISTICS
5/13/21
Ahammed T, Anjum A, Rahman MM, et al. | Health Sci Rep
Aim: To estimate the R0 and CFR of COVID-19 and assess whether the parameters vary in different regions of the world.
UPDATED
INFECTION CONTROL
5/13/21
Martimbianco ALC, Pacheco RL, Bagattini AM, et al. | Int J Clin Pract
Aim: To identify, systematically evaluate and summarise the best available evidence on the frequency of long COVID (post-acute COVID-19 syndrome), its clinical manifestations and the criteria used for diagnosis.
UPDATED
CLINICAL CHARACTERISTICS
5/13/21
Okoli GN, Rabbani R, Copstein L, et al. | Infect Dis
Aim: To review the evidence on the treatment of COVID-19 with remdesivir.
CANDIDATE THERAPEUTICS
5/13/21
Moezzi M, Shirbandi K, Shahvandi HK, et al. | Inform Med Unlocked
Aim: To summarize all the data currently available on the AI-assisted CT-Scan prediction accuracy for COVID-19.
DIAGNOSTICS
5/12/21
Round T, L'Esperance V, Bayly J, et al. | Br J Cancer
Aim: To review the evidence on delivering lung cancer care during the COVID-19 pandemic.
CLINICAL CHARACTERISTICS
5/12/21
Lin Z, Chen J, Han S | Expert Rev Anticancer Ther
Aim: To assess whether anti-cancer therapies such as surgery, chemotherapy, immunotherapy, and targeted therapy will increase the severity and mortality of cancer patients with COVID-19.
5/12/21
Azene AG, Workie MS, Aragaw AM | Curr Ther Res Clin Exp
Aim: To assess the pooled status of knowledge, attitude, and prevention practices regarding COVID -19 in Ethiopia.
INFECTION CONTROL
5/11/21
Shorey SY, Ng ED, Chee CYI | Scand J Public Health
Aim: To examine the prevalence of antenatal and postnatal anxiety and depressive symptoms among pregnant women and postpartum mothers during the COVID-19 period.
MENTAL HEALTH
5/11/21
Keshavarz P, Yazdanpanah F, Azhdari S, et al. | J Med Virol
Aim: To demonstrate the relationship between severely ill cases of MIS-C and COVID-19.
CLINICAL CHARACTERISTICS
5/11/21
Galanis P, Vraka I, Fragkou D, et al. | Am J Infect Control
Aim: To assess the impact of PPE use on HCWs' physical health and we examined factors related to a greater risk of adverse events due to PPE use.
INFECTION CONTROL
5/11/21
Rachel JB, Gururaj N, Smitha T, et al. | J Oral Maxillofac Pathol
Aim: To understand study the strain variants, all possible modes of transmission, pathogenesis, and manifestations mentioned in predominant literature published during the pandemic.
DIAGNOSTICS
5/11/21
Born J, Beymer D, Rajan D, et al. | Patterns
Aim: To address the utility of AI in imaging for COVID-19 patient care.
DIAGNOSTICS
5/11/21
Zippi M, Fiorino S, Budriesi R, et al. | World J Clin Cases
Aim: To identify studies on the relationship between the intake of PPIs and coronavirus disease 2019 (COVID-19) in patients affected by SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
5/11/21
Las Casas Lima MH, Cavalcante ALB, Leão SC | Braz J Otorhinolaryngol
Aim: To analyze current scientific evidence intended to elucidate the pathophysiological relationship between COVID-19 and the cause of olfactory disorders.
CLINICAL CHARACTERISTICS
5/11/21
Jaffe TA, Hayden E, Uscher-Pines L, et al. | J Am Coll Emerg Physicians Open
Aim: To describe the landscape of telehealth initiatives in emergency care that have been described during the coronavirus disease 2019 pandemic.
INFECTION CONTROL
5/11/21
Oscanoa TJ, Amado J, Vidal X, et al. | Adv Respir Med
Aim: To conduct a metanalysis of the association between 25-hydroxyvitamin D (25(OH)D) concentration and SARS-CoV-2 infection severity or mortality.
CLINICAL CHARACTERISTICS
5/11/21
Wijaya I, Andhika R, Huang I, et al. | Clin Epidemiol Glob Health
Aim: To assess the efficacy of JAK inhibitors in terms of clinical outcome, including mortality, clinical improvement, and clinical deterioration among hospitalized COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/11/21
Chowdhury N, Khalid A, Turin TC | Z Gesundh Wiss
Aim: To quickly synthesize existing literature about misinformation during recent abrupt large-scale infectious disease outbreaks.
INFECTION CONTROL
5/10/21
Kim H, Hwang H, Hong H, et al. | Sci Rep
Aim: To review the differences in risk factors for critical outcomes of patients with COVID-19 according to the continent on which the studies were performed.
CLINICAL CHARACTERISTICS
5/10/21
Taha M, Samavati L | RMD Open
Aim: To examine the prevalence of aPL and its clinical impact in patients with COVID-19.
CANDIDATE THERAPEUTICS
5/10/21
Ghodsi A, Bijari M, Alamdaran SA, et al. | World J Pediatr
Aim: To evaluate the chest computed tomography (CT) findings in infants with confirmed COVID-19 infection
CLINICAL CHARACTERISTICS
5/10/21
Dong Y, Shamsuddin A, Campbell H, et al. | J Glob Health
Aim: To describe existing SARS-CoV-2 therapeutic approaches and present the results of their current COVID-19 clinical trials.
CANDIDATE THERAPEUTICS
5/10/21
Menon T, Gandhi SAQ, Tariq W, et al. | Cureus
Aim: To provide an association between CKD and the clinical prognosis of COVID-19.
CLINICAL CHARACTERISTICS
5/10/21
Saadatjoo S, Miri M, Hassanipour S, et al. | Public Health
Aim: To investigate and synthesize the current evidence on knowledge, attitudes, and practices (KAPs) of the general population regarding COVID-19.
INFECTION CONTROL
5/10/21
Ippolito M, Catalisano G, Marino C, et al. | Resuscitation
Aim: To estimate the mortality rate, the rate of return of spontaneous circulation (ROSC) and survival with favorable neurological outcome in patients with COVID-19 after in-hospital cardiac arrest (IHCA) and attempted cardiopulmonary resuscitation (CPR).
CLINICAL CHARACTERISTICS
5/10/21
Musuuza JS, Watson L, Parmasad V, et al. | PLoS One
Aim: To examine the occurrence of co-infections and superinfections and their outcomes among patients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
5/10/21
Turner S, Botero-Tovar N, Herrera MA, et al. | Implement Sci
Aim: To depict the experiences and perceptions of organisations and actors at multiple levels of health systems internationally in responding to COVID-19.
UPDATED
INFECTION CONTROL
5/10/21
Klassen SA, Senefeld JW, Johnson PW | Mayo Clin Proc
Aim: To determine the effect of COVID-19 convalescent plasma on mortality.
CANDIDATE THERAPEUTICS
5/10/21
Lazaridis D, Leung S, Kohler L, et al. | J Pharm Pract
Aim: To review the evidence on the impact of anticoagulation on COVID-19 patient outcomes.
CANDIDATE THERAPEUTICS
5/7/21
Watt JA, Lane NE, Veroniki AA, et al. | J Am Geriatr Soc
Aim: To compare the diagnostic accuracy of virtual to in-person cognitive assessments and tests and barriers to virtual cognitive assessment implementation.
DIAGNOSTICS
5/7/21
Gulsen A, Konig I, Jappe U, et al. | Respirology
Aim: To examine in detail whether the underlying chronic obstructive pulmonary diseases (COPD), asthma and chronic respiratory diseases (CRDs) were associated with an increased risk of more severe COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
5/7/21
Mutiawati E, Syahrul S, Fahriani M, et al. | F1000Res
Aim: To determine the prevalence of headache in coronavirus disease 2019 (COVID-19) and to assess its association as a predictor for COVID-19.
CLINICAL CHARACTERISTICS
5/7/21
Aladawi M, Elfil M, Abu-Esheh B, et al. | Can J Neurol Sci
Aim: To review the evidence on the association between Guillain Barre Syndrome and COVID-19.
CLINICAL CHARACTERISTICS
5/7/21
Dembrovszky F, Váncsa S, Farkas N, et al. | Viruses
Aim: To evaluate which prognostic factors may impact repeated SARS-CoV-2 positivity (RSP) and their association with immunoglobulin detectability among recovered patients. 
UPDATED
CLINICAL CHARACTERISTICS
5/7/21
Rosenberger KJ, Xu C, Lin L | J Eval Clin Pract
Aim: To methodologically assess the current systematic reviews and meta-analyses on COVID-19.
5/7/21
Aldien AS, Ganesan GS, Wahbeh F, et al. | Cardiovasc Revasc Med
Aim: To investigate the possible role of hyperinflammation in inducing cardiac injury as one of the severe complications of COVID-19.
CLINICAL CHARACTERISTICS
5/7/21
Lu Y, Zhao J, Ye M, et al. | Neurol Sci
Aim: To determine the risk of acute ischemic stroke in patients with severe and non-severe coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
5/7/21
Cosco TD, Best J, Davis D, et al. | Age Aging
Aim: To quantify the association between frailty and COVID-19 in relation to mortality in hospitalised patients.
UPDATED
CLINICAL CHARACTERISTICS
5/6/21
Chee ML, Ong MEH, Siddiqui FJ, et al. | Int J Environ Res Public Health
Aim: To systematically review and critically appraise the current evidence on AI applications for COVID-19 in intensive care and emergency settings.
DIAGNOSTICS
5/6/21
Ayubi E, Bashirian S, Khazaei S | J Gastrointest Cancer
Aim: To systematically review and meta-analysis of studies that evaluated the level of depression and anxiety in cancer patients during the COVID-19 pandemic.
MENTAL HEALTH
5/6/21
 | Pan American Health Organization
Aim: To review the evidence on the therapeutic options for COVID-19.
5/6/21
Angelico R, Blasi F, Manzia TM, et al. | Medicina
Aim: To investigate the current management of IS therapy in KT recipients with COVID-19. 
CLINICAL CHARACTERISTICS
5/6/21
Suklan J, Cheaveau J, Hill S, et al. | Viruses
Aim: To statistically summarise routine laboratory biomarker measurements in COVID-19-positive and -negative patients to inform future work.
DIAGNOSTICS
5/6/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the role of daycares and schools in the transmission of COVID-19.
UPDATED
5/5/21
Shah R, Priyadarshini G, Parsana M | Indian J Otolaryngol Head Neck Surg
Aim: To give a brief review of available data on COVID-19 related to the timing, personal protections, operative steps modifications, and subsequent post tracheostomy care during this pandemic.
CANDIDATE THERAPEUTICS
5/5/21
Szarpak L, Borkowska M, Peacock FW, et al. | Cardiol J
Aim: To review interventional outcome studies in patients with in-hospital cardiac arrest before and during the coronavirus disease 2019 (COVID-19) pandemic period.
CLINICAL CHARACTERISTICS
5/5/21
Li X, Zhong X, Wang Y, et al. | PLoS One
Aim: To systematically identify the possible risk factors responsible for severe cases.
CLINICAL CHARACTERISTICS
5/5/21
Yousefi M, Oskoei V, Jafari AJ, et al. | Environ Sci Pollut Res Int
Aim: To determine the effects of COVID-19 on the quantity of waste and municipal solid waste management.
INFECTION CONTROL
5/5/21
Chetty T, Ramokolo V, Rees K, et al. | S Afr Med J
Aim: To assess the effectiveness of cloth and medical masks for preventing SARS-CoV-2 transmission in community settings.
INFECTION CONTROL
5/5/21
Rehman MA, Farooq H, Ali MM, et al. | SN Compr Clin Med
Aim: To identify cases of subacute thyroiditis associated with COVID-19 and evaluated patient-level demographics, major clinical features, laboratory findings and outcomes.
CLINICAL CHARACTERISTICS
5/4/21
Du P, Li D, Wang A, et al. | Can J Infect Dis Med Microbiol
Aim: To screen the risk factors for severe illness and death and provide help for early clinical treatment of the new coronavirus (COVID-19).
CLINICAL CHARACTERISTICS
5/4/21
Bilal U, Gullón P, Padilla-Bernáldez J | Gac Sanit
Aim: To review the scientific epidemiologic evidence on the role of hospitality venues in the incidence or mortality from COVID-19.
INFECTION CONTROL
5/4/21
Dos Santos ACM, Dos Santos BRC, Dos Santos BB, et al. | Infect Genet Evol
Aim: to review the effect of single nucleotide polymorphisms in the development of severe acute respiratory syndrome (SARS).
UPDATED
CLINICAL CHARACTERISTICS
5/4/21
Hariyanto TI, Rosalind J, Christian K, et al. | South Afr J HIV Med
Aim: To explore the impact of HIV and SARS-CoV-2 co-infection on mortality.
CLINICAL CHARACTERISTICS
5/4/21
Nepal G, Shrestha GS, Rehrig JH, et al. | J Nepal Health Res Counc
Aim: To review the evidence on neurological involvement in COVID-19 associated MIS-C.
CLINICAL CHARACTERISTICS
5/4/21
Liang M, Luo N, Chen M, et al. | Infect Dis Ther
Aim: To investigate the prevalence and mortality in PLWHA co-infected with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/3/21
Peixoto AO, Costa RM, Uzun R, et al. | Pulmonology
Aim: To review the evidence on the use of lung ultrasound in COVID-19.
5/3/21
Pb S, Mittal S, Madan K, et al. | Monaldi Arch Chest Dis
Aim:  To evaluate the available evidence and performed meta-analysis of the effect of awake PP in non-intubated patients on improvement in oxygenation and reducing the need for intubation.
5/3/21
Siegel A, Zuo Y, Moghaddamcharkari N, et al. | Curr Opin Psychiatry
Aim: To synthesize the extant literature reporting on barriers of telemental health (TMH) during the COVID-19 pandemic and how facilities have worked to overcome these barriers, to inform best practices for TMH delivery.
5/3/21
Neira C, Godinho R, Rincon F, et al. | Nutrients
Aim: To evaluate the current evidence about the impact that preventive measures of physical contact restriction causes in healthy nutrition.
UPDATED
5/3/21
Gianfredi V, Mauer NS, Gentile L, et al. | Int J Environ Res Public Health
Aim: To evaluate the available scientific evidence on the risks of recreational skiing for the evolution of the COVID-19 pandemic.
5/3/21
Corrao S, Mallaci Bocchio R, Lo Monaco M, et al. | Nutrients
Aim: To analyze the current knowledge from systematic reviews of the relationship between nutraceutical supports and the reduction in inflammatory response to formulate clinical recommendations and highlight directions for future research during the COVID-19 pandemic. 
5/3/21
Nobari H, Fashi M, Eskandari A, et al. | Int J Environ Res Public Health
Aim: To assess and provide an up-to-date analysis of the impact of coronavirus disease 2019 (COVID-19) pandemic on the health-related quality of life (HRQoL) of children and adolescents.
5/3/21
Tleyjeh IM, Kashour Z, Riaz M, et al. | Clin Microbiol Infect
Aim: To perform a living systematic review of the literature about the efficacy and toxicity of the IL-6 receptor antagonist, tocilizumab, in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/3/21
Regmi K, Lwin CM | Int J Environ Res Public Health
Aim: To review the factors associated with the implementation of NPIs (social distancing, social isolation and quarantine) for reducing COVID-19.
5/3/21
La Verde M, Riemma G, Torella M, et al. | Int J Gynaecol Obstet
Aim: To evaluate the characteristics of pregnant women deceased due to COVID-19.
UPDATED
5/3/21
Putri C, Hariyanto TI, Hananto JE, et al. | Parkinsonism Relat Disord
Aim: To analyze the relationship between PD and in-hospital outcomes of COVID-19.
5/3/21
Diaz-Arocutipa C, Saucedo-Chinchay J, Imazio M, et al. | J Cardiovasc Med
Aim: To summarize the clinical features, diagnostic methods, treatment, and outcomes of coronavirus disease 2019 (COVID-19) patients with pericarditis.
5/3/21
Ponnapa Reddy M, Subramaniam A, et al. | Crit Care Med
Aim: To evaluate the impact of prone positioning on oxygenation and clinical outcomes.
5/3/21
Mojahed A, Brym S, Hense H, et al. | Front Psychiatry
Aim: To review the evidence on the context of social and geographical isolation and their associations with intimate partner violence.
5/3/21
Dramé M, Cofais C, Hentzien M, et al. | Nutrients
Aim: To identify and synthesize the best available evidence on the association between vitamin D level and risk of COVID-19, adverse outcomes and possible benefits of supplementation aged 60 years or over.
UPDATED
5/3/21
Magnavita N, Chirico F, Garbarino S, et al. | Int J Environ Res Public Health
Aim: To summarize and combine relevant data from existing systematic reviews and meta-analyses in order to evaluate the association of coronaviruses (SARS, MERS, SARS-CoV-2) with BOS in HCWs.
5/3/21
Mogensen MA, Wangaryattawanich P, Hartman J, et al. | Br J Radiol
Aim: To describe outcomes associated with abnormal neuroimaging findings among adult COVID-19 patients.
CLINICAL CHARACTERISTICS
5/3/21
Hasan T, Beardsley J, Marais BJ, et al. | Vaccines
Aim: To assess the publicly-available policies and implementation strategies used for COVID-19 mass vaccination.
5/3/21
Bareille M, Hardy M, Douxfils J, et al. | J Clin Med
Aim: To assess the potential usefulness of viscoelastometric testing (VET) to predict thrombotic events in COVID-19 patients.
5/1/21
Tharmarajah E, Buazon A, Patel V, et al. | J Infect
Aim: To assess the impact of IL-6 inhibition on mortality in the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/30/21
 | NSW Health COVID-19 Critical Intelligence Unit
4/30/21
Sahu AK, Mathew R, Aggarwal P, et al. | J Glob Infect Dis
Aim: To investigate the clinical characteristics that can predict COVID-19 disease severity.
MENTAL HEALTH
4/30/21
 | NSW Health COVID-19 Critical Intelligence Unit
4/30/21
Lee J, Song J | J Med Virol
Aim: To investigate the diagnostic accuracy of the Xpert Xpress and the ID NOW assays for rapid detection of SARS-CoV-2.
CLINICAL CHARACTERISTICS
4/30/21
Crawshaw J, Konnyu K, Castillo G, et al. | The Ottawa Hospital Research Institute
Aim: To review the evidence on how behavioural science can help inform messaging to and broader supports for the general public to encourage vaccination for COVID-19.
4/30/21
Blum P, Putzer D, Liebensteiner MC, et al. | In Vivo
Aim: To provide a systematic review of the published literature on the impact by the Covid-19 pandemic on orthopaedic and traumatological care by focusing on the number of clinical visits, surgeries and reasons for consultation.
4/30/21
Laali A, Tabibzadeh A, Esghaei P, et al. | Adv Biomed Res
Aim: To review the evidence on liver function tests profile in COVID-19 patients at the admission time.
INFECTION CONTROL
4/30/21
Peiris S, Mesa H, Aysola A, et al. | PLoS One
Aim: To summarize the reported pathologic findings on biopsy and autopsy in patients with severe/fatal COVID-19 and documented the presence and/or effect of SARS-CoV-2 in all organs.
CLINICAL CHARACTERISTICS
4/30/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on what is known about reasons for vaccine confidence and uptake in populations experiencing inequities.
4/30/21
Zhang L, Pan R, Cai Y, et al. | Psychiatry Investig
Aim: To investigate the prevalence of post-traumatic stress disorder (PTSD) in the general population during the COVID-19 pandemic.
DIAGNOSTICS
4/29/21
Córdova LDS, Vega APM, Luján-Carpio E, et al. | Dement Neuropsychol
Aim: To describe the characteristics of COVID-19 patients, both over and under 80 years old, by conducting a systematic review of the literature describing case reports, and to summarize and critically assess these characteristics.
4/29/21
Schlesinger S, Neuenschwander M, Lang A, et al. | Diabetologia
Aim: To identify high-risk phenotypes of diabetes associated with COVID-19 severity and death.
4/29/21
Choudary MC, Crain CR, Qiu X, et al.  | Clin Infect Dis
Aim: To characterize the hallmarks of reinfecting sequences and the rate of viral evolution in persistent infection.
UPDATED
CLINICAL CHARACTERISTICS
4/29/21
Hammond A, Khalid T, Thornton HV, et al. | PLoS One
Aim: To investigate whether modern portable, commercially available air filters reduce the incidence of respiratory infections and/or remove bacteria and viruses from indoor air.
UPDATED
INFECTION CONTROL
4/29/21
Rogers JP, Chesney E, Oliver D, et al. | Epidemiol Psychiatr Sci
Aim: To establish whether infectious epidemics are associated with any changes in the incidence of suicide or the period prevalence of self-harm, or thoughts of suicide or self-harm, with a secondary objective of establishing the frequency of these outcomes.
4/28/21
Ren X, Ren X, Lou J, et al. | EClinicalMedicine
Aim: To comprehensively analyze the COVID-19 patients with RP RT-PCR result after discharged through the inclusion of extensive relevant studies; focus on the clinical characteristics, the possible causes and risk factors.
4/28/21
Elavarasi A, Sahoo RK, Seth T, et al. | Natl Med J India
Aim: To review the evidence on anti-IL-6 therapies in the treatment of COVID-19.
4/28/21
Hayward SE, Deal A, Cheng C, et al. | J Migr Health
Aim: To assess clinical outcomes of COVID-19 in migrant populations (cases, hospitalisations, deaths), indirect health and social impacts, and to determine key risk factors.
UPDATED
CLINICAL CHARACTERISTICS
4/28/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on COVID-19 vaccination for immunocompromised patients including risks and adverse events, efficacy and advice from professional colleges.
4/28/21
Bartoszko JJ, Siemieniuk RAC, Kum E, et al. | BMJ
Aim: To determine and compare the effects of drug prophylaxis on severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (covid-19).
UPDATED
4/27/21
Sheikh AB, Chourasia PK, Javed N, et al. | J Neuroimmunol
Aim: To determine demographic characteristics, clinical features, lab evaluation, management and complications of the studies focusing on Guillain-Barre syndrome (GBS) as a sequele of novel coronavirus (COVID-19) infection.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Vassilopoulou E, Feketea G, Koumbi L, et al. | Front Immunol
Aim: To summarize the current evidence, collected in a systematic literature search and narrative review of original articles related to breastfeeding by SARS-CoV-2–infected mothers, and deploying knowledge gained from other respiratory virus-transmitted diseases about the protective anti-inflammatory effects of breastfeeding. 
INFECTION CONTROL
4/27/21
Yu J, Wu B, Feng L, et al. | J Tissue Viability
Aim: To summarize the pressure injuries caused by COVID-19 and the corresponding preventive measures and treatments.
CLINICAL CHARACTERISTICS
4/27/21
Siemieniuk RAC, Bartoszko JJ, Ge L, et al. | BMJ
Aim: To compare the effects of treatments for coronavirus disease 2019 (covid-19).
UPDATED
CANDIDATE THERAPEUTICS
4/27/21
Mitaka H, Kuno T, Takagi H, et al. | Mycoses
Aim: To determine the incidence and mortality of CAPA in critically ill patients with COVID-19 to improve guidance on surveillance and prognostication.
CLINICAL CHARACTERISTICS
4/27/21
Spielberger BD, Goerne T, Geweniger A, et al. | Front Pediatr
Aim: To systematically review the current evidence on transmission of SARS-CoV-2 to and by children.
INFECTION CONTROL
4/27/21
Bansal V, Mahapure KS, Mehra I, et al. | Front Med
Aim: To appraise the currently available data for the clinical usefulness of convalescent plasma for the treatment of COVID-19. 
CANDIDATE THERAPEUTICS
4/27/21
Patralekh MK, Jain V, Iyengar K, et al.  | J Clin Orthop Trauma
Aim: To evaluate the impact of COVID-19 on patients with PFF and assessed associated mortality.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Hossain MM, Rahman M, Trisha NF, et al. | Heliyon
Aim: To estimate the pooled prevalence of anxiety and depression in South Asia during COVID-19. 
MENTAL HEALTH
4/27/21
Ouyang L, Yu M, Zhu Y, et al. | Heliyon
Aim: To describe the respiratory supports and determine their association with clinical outcomes of COVID-19 patients in intensive care unit (ICU).
CANDIDATE THERAPEUTICS
4/27/21
Wu Y, Li H, Zhang Z, et al. | Ann Palliat Med
Aim: To evaluate the in-hospital mortality and risk factors of death in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Mackey K, Kansagara D, Vela K | Ann Intern Med
Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.
UPDATED
WHO COLLABORATIVE
VA ESP
4/26/21
Garcia-Zamora S, Lee S, Haseeb S, et al. | Pacing Clin Electrophysiol
Aim: To examine the prevalence of cardiac arrhythmias detected by the electrocardiogram and their relationships with adverse outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Barreira DF, Lourenço RA, Calisto R, et al. | Front Med
Aim: To evaluate the potential of using CP or enriched antibodies from plasma (hyperimmune plasma) for the treatment of COVID-19 in comparison to standard treatment (ST) (treatments performed without CP), in clinical trials.
CANDIDATE THERAPEUTICS
4/26/21
Singh RK, Bajpai R, Kaswan P | Clin Epidemiol Glob Health
Aim: To systematically review existing literature reporting the prevalence of psychological wellbeing (such as stress, anxiety, depression, psychological distress & sleep disorders, etc.), particularly from the Indian perspective as a limited evidence synthesis published so far.
MENTAL HEALTH
4/26/21
Varghese A, George G, Kondaguli SV, et al. | J Glob Health
Aim: To explore the prevalence and determinants of mental health outcomes (anxiety, stress, depression, PTSD, insomnia) among nurses across the globe due to the COVID-19.
UPDATED
MENTAL HEALTH
4/26/21
Ma Z, Wang MP, Liu L, et al. | Aging
Aim: To review the evidence on whether ACEI and/or ARB are associated with the risk of SARS-COV2 infection and whether they are associated with adverse outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Muller AE, Himmels JPW, Van de Velde S | BMC Med Res Methodol
Aim: To review the diagnostic tests developed to assess or diagnose COVID-19-related fear or phobia.
UPDATED
MENTAL HEALTH
4/26/21
Wolf S, Seiffer B, Zeibig JM, et al. | Sports Med
Aim: To provide a systematic overview of the literature with regard to associations between physical activity (PA) and depression and anxiety during the COVID-19 pandemic.
MENTAL HEALTH
4/26/21
Singh J, Malik P, Patel N, et al. | Clin Exp Med
Aim: To identify prevalence and association of comorbid chronic kidney disease (CKD), acute kidney injury (AKI) and utilization prevalence of continuous renal replacement therapy (CRRT) in COVID-19-hospitalized patients as a function of severity status. 
CLINICAL CHARACTERISTICS
4/26/21
Parsons N, Outsikas A, Parish A, et al. | AJNR Am J Neuroradiol
Aim: To quantitatively evaluate whether a network diffusion model can explain the spread of small neurologic events.
CLINICAL CHARACTERISTICS
4/26/21
Hariyanto TI, Kurniawan A | Sleep Med
Aim: To analyze the relationship between OSA and poor outcomes of COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Dmytriw AA, Chibbar R, Chen PPY, et al. | Expert Rev Respir Med
Aim: To review the evidence on the outcomes of patients with COVID-19-related ARDS compared to ARDS unrelated to COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Gascon L, Fournier I, Chiesa-Estomba C, et al. | Eur Arch Otorhinolaryngol
Aim: To summarize, in a systematic way, all available guidelines and provide clear guidelines for the management of head and neck cancer patients in the COVID-19 pandemic.
INFECTION CONTROL
4/26/21
Bakaloudi DR, Jeyakumar DT, Jayawardena R, et al. | Clin Nutr
Aim: To investigate changes in specific dietary habits (snacking, fast-foods, ordered food) and alcohol consumption during the COVID-19 lockdown period compared to pre lockdown time.
MENTAL HEALTH
4/26/21
Souza LFF, Paineiras-Domingos LL, Melo-Oliveira MES, et al. | Cien Saude Colet
Aim: To evaluate the sleep quality in individuals during the COVID-19 pandemic by Pittsburgh Sleep Quality Index (PSQI).
MENTAL HEALTH
4/26/21
Chong WH, Neu KP | J Hosp Infect
Aim: To discuss the incidence, characteristics, diagnostic criteria, biomarkers, and outcomes of hospitalized patients diagnosed with CAPA.
CLINICAL CHARACTERISTICS
4/26/21
Iwu CJ, Iwu CD, Wiysonge CS | Pan Afr Med J
Aim: To synthesize evidence on the long-term effects of the SARS-CoV-2 infection among survivors.
CLINICAL CHARACTERISTICS
4/23/21
Payedimarri AB, Concina D, Portinale L, et al. | Int J Environ Res Public Health
Aim: To evaluate the effectiveness of the use of AI and ML when applied to public health interventions to contain the spread of SARS-CoV-2. 
INFECTION CONTROL
4/22/21
Thakur B, Dubey P, Benitez J, et al.  | Sci Rep
Aim: To determine geographical, age, and gender related differences in the prevalence of comorbidities and associated severity and mortality rates among COVID-19 patients.
CLINICAL CHARACTERISTICS
4/22/21
Lu W, Zheng Y, Liu J, et al.  | Aging
Aim: To evaluate the efficacy and safety of lopinavir/ritonavir antiviral treatment in patients with SARS, MERS, and COVID-19.
CANDIDATE THERAPEUTICS
4/22/21
Chan KIP, Salonga AEM, Khu KJO | Surg Neurol Int
Aim: To review the evidence on decompressive hemicraniectomy for acute ischemic stroke and share a case presentation.
CANDIDATE THERAPEUTICS
4/22/21
Menon T, Sharma R, Saurabh K, et al.  | Cureus
Aim: To measure the prevalence of acute kidney injury (AKI) in COVID-19 and its association with the disease severity and mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/22/21
Qiu R, Li J, Xiao Y, et al.  | Medicine
Aim: To evaluate the efficiency and safety of the COVID-19 medicine.
CANDIDATE THERAPEUTICS
4/21/21
Moonla C, Sosothikul D, Chiasakul T, et al. | Clin Appl Thromb Hermost
Aim: To estimate pooled odds ratios (ORs) of in-hospital mortality and major bleeding comparing among intermediate-to-therapeutic dose AC, prophylactic dose AC, and no AC.
CANDIDATE THERAPEUTICS
4/21/21
Chaudhuri D, Sasaki K, Aram K, et al. | Intensive Care Med
Aim: To summarize all RCTs examining the use of corticosteroids in ARDS.
CANDIDATE THERAPEUTICS
4/21/21
Chowdhury AI, Alam MR, Rabbi MF, et al.  | Obes Med
Aim: To estimate the effects of overweight and obesity on COVID-19 disease severity.
CLINICAL CHARACTERISTICS
4/21/21
Medaglia AA, Siracusa L, Gioè C, et al.  | Ital J Pediatr
Aim: To review the medical literature on Kawasaki disease recurrence and reported a new case of Kawasaki disease recurrence in a child with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
4/21/21
Dy LF, Lintao RCV, Cordero CP, et al.  | Sci Rep
Aim: To estimate the proportion of COVID-19 patients with cardiac abnormalities and to determine the association between the cardiac abnormalities in COVID-19 patients and disease severity and mortality.
CLINICAL CHARACTERISTICS
4/21/21
Goldstein KM, Ghadimi K, Mystakelis H, et al. | J Aerosol Med Pulm Drug Deliv
Aim: To assess the risk of transmitting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS, Middle East respiratory syndrome (MERS), and influenza with administration of drugs via nebulizer.
INFECTION CONTROL
4/20/21
Cheng MP, Cau A, Lee TC, et al.  | Crit Care Med
Aim: To compare the rates of cardiac injury by angiotensin-converting enzyme-2-binding viruses from viruses that do not bind to angiotensin-converting enzyme-2.
CLINICAL CHARACTERISTICS
4/20/21
Pizarro-Pennarolli C, Sánchez-Rojas C, Torres-Castro R, et al.  | PeerJ
Aim: To understand the impact of COVID-19 on ADL performance of adult patients and to describe the common scales used to assess performance of ADL on patients post-COVID-19.
CLINICAL CHARACTERISTICS
4/20/21
Sathian B, Asim M, Banerjee I, et al.  | Nepal J Epidemiol
Aim: To evaluate the safety and immunogenicity of novel COVID-19 vaccine candidates under clinical trial evaluation and present a contemporary update on the development and implementation of a potential vaccines.
INFECTION CONTROL
4/20/21
Artemios A, Andreas L, Hadjigeorgiou L, et al. | Neurol Res
Aim: To characterize all – to date – reported cases with COVID-19 related myelopathy.
CLINICAL CHARACTERISTICS
4/20/21
Mondello C, Roccuzzo S, Malfa O, et al.  | Front Pharmacol
Aim: To review the main post-mortem findings reporting data on the infection effects on several organs.
CLINICAL CHARACTERISTICS
4/20/21
Pecho-Silva S, Navarro-Solsol AC, Taype-Rondan A, et al. | Ultrasound Med Biol
Aim: To systematize the evidence on pulmonary ultrasound (PU) use in diagnosis, monitorization or hospital discharge criteria for patients with coronavirus disease 2019 (COVID-19).
DIAGNOSTICS
4/20/21
Parra-Medina R, Herrera S, Jaime M, et al. | Acta Haematol
Aim: To review cases in the literature about COVID-19 autopsies that reported microthrombi in different organs.
CLINICAL CHARACTERISTICS
4/20/21
Long J, Luo Y, Wei Y, et al. | Am J Emerg Med
Aim: To evaluate the mortality risks associated with CVD and cardiac injury among hospitalized COVID-19 patients, especially in subgroups of populations in different countries.
CLINICAL CHARACTERISTICS
4/19/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy of rapid, point-of-care tests for COVID-19.
4/19/21
Morris AM, Bean S, Bell CM, et al. | Ontario COVID-19 Science Advisory Table
Aim: To review the evidence on strategies to manage tocilizumab supply during the COVID-19 pandemic.
CANDIDATE THERAPEUTICS
4/17/21
Sing A, Hussain S, Antony B | Diabetes Metab Syndr
Aim: To systematically review the evidence on clinical outcomes in NAFLD patients with COVID-19.
CLINICAL CHARACTERISTICS
4/17/21
Barcelos IDES, Penna IAA, Soligo AG, et al. | Rev Bras Ginecol Obstet
Aim: To evaluatee the available evidence on vertical transmission by severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2.
INFECTION CONTROL
4/16/21
Akbar MR, Wibowo A, Pranata R, et al. | Front Nutr
Aim: To assess whether low serum 25-hydroxyvitamin D (25-OHD) level is associated with susceptibility to COVID-19, severity, and mortality related to COVID-19.
CLINICAL CHARACTERISTICS
4/16/21
Damiano RF, Di Santi D, Beach S, et al. | Braz J Psychiatry
Aim: To review the most common mental health strategies aimed at alleviating and/or preventing mental health problems in individuals during the coronavirus disease 2019 (COVID-19) and other coronavirus pandemics.
UPDATED
MENTAL HEALTH
4/16/21
Zuin M, Rigatelli G, Bilato C, et al. | J Interv Card Electrophysiol
Aim: To investigate the pooled prevalence of pre-existing AF and its short-term mortality risk in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/15/21
Kashetsky N, Mukovozov IM, Bergman J. | J Cutan Med Surg
Aim: To summarize reports of CLL coinciding with SARS-CoV-2 infection to clarify the prevalence, clinical relevance, and prognostic value of these lesions.
CLINICAL CHARACTERISTICS
4/15/21
De Armond M, Feliciano S, Hirabayashi E, et al.  | JBI Evid Synth
4/15/21
Parisi R, Costanzo S, Di Castelnuovo A, et al. | Semin Thromb Hemost
Aim: To assess the association of anticoagulants and their dosage with in-hospital all-cause mortality in COVID-19 patients.
CANDIDATE THERAPEUTICS
4/15/21
Nopsopon T, Kittrakulrat J, Takkavatakarn K, et al. | Kidney Int Rep
Aim: To evaluate the prevalence and case fatality rate (CFR) of COVID-19 infection in ESRD patients with hemodialysis, peritoneal dialysis, and kidney transplantation.
CLINICAL CHARACTERISTICS
4/15/21
Nopsopon T, Pongpirul W, Takkavatakarn K, et al. | Kidney Int Rep
Aim: To evaluate the prevalence and case fatality rate (CFR) of COVID-19 infection in ESRD patients with hemodialysis.
CLINICAL CHARACTERISTICS
4/15/21
Nopsopon T, Eiamsitrakoon T, Takkavatakarn K, et al. | Kidney Int Rep
Aim: To evaluate the prevalence and case fatality rate (CFR) of COVID-19 infection in PD patients.
CLINICAL CHARACTERISTICS
4/15/21
Nopsopon T, Kittrakulrat J, Takkavatakarn K, et al. | Kidney Int Rep
Aim: To evaluate the prevalence and case fatality rate (CFR) of COVID-19 infection in KT patients.
CLINICAL CHARACTERISTICS
4/15/21
Chew NW, Ow ZGW, Teo VXY, et al. | Can J Cardiol
Aim: To examine the global impact of COVID-19 pandemic on incidence of STEMI admissions, and relationship between the pandemic and door-to-balloon time (D2B), all-cause mortality and other secondary STEMI outcomes.
4/14/21
Sohrabizadeh S, Yousefian S, Bahramzadeh A, et al. | BMC Public Health
Aim: To identify the literature focused on health system response to coincidence of COVID-19 and disasters as well as describing their finding, implications and lessons-learned.
4/14/21
Qi K, Zeng W, Ye M, et al. | Medicine
Aim: To describe the clinical, laboratory, and imaging characteristics of children with COVID-19 based on published data of pediatric COVID-19 cases.
CLINICAL CHARACTERISTICS
4/14/21
Mondal R, Deb S, Shome G, et al. | Mult Scler Relat Disord
Aim: To summarize so far available pieces of evidence documenting de novo novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) mediated spinal cord demyelinating diseases.
UPDATED
CLINICAL CHARACTERISTICS
4/14/21
Flook M, Jackson C, Vasileiou E, et al. | BMC Infect Dis
Aim: To review the evidence on the risk factors for severity, disease, and mortality for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Katoto PDMC, Brand AS, Bakan B, et al. | Environ Health
Aim: To review the evidence on whether exposure to acute and chronic air pollution influences the COVID-19 epidemiologic curve.
CLINICAL CHARACTERISTICS
4/13/21
Batista P, Duque V, Luzio-Vaz A | J Infect Dev Ctries
Aim: To identify studies that describe COVID-19 related anxiety, and to understand the impact of anxiety assessment in defining strategies to be implemented in future studies.
MENTAL HEALTH
4/13/21
Yao MQ, Zheng QX, Xu J, et al. | Zhejiang Univ Sci B
Aim: To summarize the demographical, clinical, and laboratorial characteristics of non-recurrence and recurrence groups.
CLINICAL CHARACTERISTICS
4/13/21
Handayani DR, Juliastuti H, Nawangsih EN, et al. | Obes Med
Aim: To assess the prognostic value of fasting hyperglycemia in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Pranata R, Huang I, Lawrensia S, et al. | Pharmacol Rep
Aim: To address the current interest of whether the administration of PPI could increase the susceptibility and risk of poor outcome in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Labrague LJ | J Nurs Manag
Aim: To appraise and synthesize studies examining resilience, coping behaviours, and social support among healthcare workers during the coronavirus pandemic.
MENTAL HEALTH
4/13/21
 | NSW Health COVID-19 Critical Intelligence Unit
4/13/21
Hariyanto TI, Kurniawan A | Nutr Metab Cardiovasc Dis
Aim: To analyze the association between statin use and composite poor outcomes of COVID-19.
CLINICAL CHARACTERISTICS
4/13/21
Alkhatip AAAMM, Kamel MG, Hamza MK, et al. | Expert Rev Mol Diagn
Aim: To evaluate the diagnostic and prognostic accuracy of the NLR in COVID-19 patients.
DIAGNOSTICS
4/13/21
Ibekwe T, Ibekwe P, Orimadegun EA | Ann Med Surg
Aim: To review the evidence on the effectiveness of Remdesivir in the management of COVID-19.
CANDIDATE THERAPEUTICS
4/13/21
Trimboli P, Camponovo C, Scappaticcio L, et al. | Rev Endocr Metab Disord
Aim: To review the evidence on thyroid dysfunction in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/12/21
Phiri P, Ramakrishnan R, Rathod S, et al. | EClinicalMedicine
Aim: To review the evidence on the mental health impacts of the COVID-19 pandemic on healthcare professionals, patients, and the general public.
UPDATED
MENTAL HEALTH
4/12/21
Meza N, Perez-Bracchiglione J, Perez I, et al. | Medwave
Aim: To provide a timely, rigorous, and continuously updated summary of the evidence available on the role of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) in the treatment of patients with COVID-19.
UPDATED
4/12/21
Barboza JJ, Chambergo-Michilot D, Velasquez-Sotomayor M, et al. | Travel Med Infect Dis
Aim: To describe the assessment and treatment of asymptomatic infection in patients with a confirmed diagnosis of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/12/21
Badkhsh M, Dastras M, Sarchahi Z, et al. | Rev Environ Health
Aim: To evaluate the effect of CAM interventions on COVID-19 patients.
CANDIDATE THERAPEUTICS
4/12/21
Tomfohr-Madsen L, Racine N, Giesbrecht GF, et al.  | Psychiatry Res
Aim: To analyze the worldwide prevalence of depression and anxiety among pregnant women during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
4/12/21
Park M, Pawliuk C, Nguyen T, et al. | Euro Surveill
Aim: To gain an understanding of the current literature and compare the reported periods of positive SARS-CoV-2 detection from studies that conducted RT-PCR testing in addition to experiments isolating whole virus.
INFECTION CONTROL
4/12/21
Tsang NNY, So HC, Ng KY, et al. | Lancet Infect Dis
Aim: To systematically compare the diagnostic performance of different clinical specimen collection methods.
DIAGNOSTICS
4/12/21
Rakhmat II, Kusmala YY, Handayani DR, et al. | Diabetes Metab Syndr
Aim: To synthesize evidence on dipeptidyl peptidase-4 (DPP-4) inhibitor and mortality in COVID-19 patients and factors affecting it.
UPDATED
CANDIDATE THERAPEUTICS
4/12/21
Greyson SR, Auerbach AD, Mitchell MD, et al. | J Gen Intern Med
Aim: To review published guidance and collected discharge protocols and procedures to identify and synthesize common practices.
CLINICAL CHARACTERISTICS
4/12/21
Jafari Z, Kolb BE, Mohajerani MH | Can J Neurol Sci
Aim: To systematically review current evidence regarding hearing loss, tinnitus, and dizziness caused by SARS-CoV-2, as well as determine the occurrence frequency of these symptoms through a meta-analysis.
CLINICAL CHARACTERISTICS
4/12/21
Vafea MT, Zhang R, Kalligeros M, et al. | Expert Rev Med Devices
Aim: To evaluate existing information about mortality rates and effectiveness of antiviral, immune-modulating, and anticoagulation treatments in COVID-19 patients who received mechanical ventilation.
CANDIDATE THERAPEUTICS
4/12/21
Damayanthi HDWT, Prabani KIP | Arch Gerontol Geriatr
Aim: To identify the prevalence of malnutrition and levels of nutrients associated with outcomes of the older patients with COVID-19.
CLINICAL CHARACTERISTICS
4/12/21
Nguyen T, Buxton JA | Int J Drug Policy
Aim: To review the evidence on the unintended pathways between COVID-19 public health responses and increasing illicit drug overdoses.
4/12/21
Zhang Y, Cen M, Hu M, et al. | Clin Transl Gastroenterol
Aim: To evaluate the prevalence and the duration of shedding of fecal RNA in patients with COVID-19 infection.
CLINICAL CHARACTERISTICS
4/12/21
Qiu D, Li Y, Li L, et al. | Eur Psychiatry
Aim: To examine the pooled prevalence of post-traumatic stress symptoms among people exposed to the trauma resulting from COVID-19 outbreak.
UPDATED
MENTAL HEALTH
4/12/21
Palaiodimou L, Stefanou MI, Katsanos AH, et al. | Eur J Neurol
Aim: To critically appraise the published literature related to GBSs and COVID-19, and evaluate prevalence, clinical features and outcomes of GBSs in pateints with COVID-19 compared to non-COVID-19 contemporary or historical controls.
UPDATED
CLINICAL CHARACTERISTICS
4/12/21
Dhouib W, Maatoug J, Ayouni I, et al. | Syst Rev
Aim: To identify studies that recruited symptomatic patients, regardless of sex or age diagnosed with COVID-19, and calculated or estimated the incubation period between December 2019 and December 2020.
UPDATED
CLINICAL CHARACTERISTICS
4/9/21
Ioannidis JPA | Eur J Clin Invest
Aim: To review the evidence on the extent of community spread of SARS-CoV-2 infection and the infection fatality rate (IFR) of COVID-19.
INFECTION CONTROL
4/9/21
Morales-Cane I, del Rocio Valverde-Leon M, Gonzalez-Gancedo J, et al. | Eur Rev Med Pharmacol Sci
Aim: To synthesize and analyze the scientific publications related to ventilatory therapies used in patients with COVID-19 in Intensive Care Units (ICUs), the parameters of invasive mechanical ventilation prescribed for these patients, and the clinical characteristics of patients admitted to the ICU.
UPDATED
CANDIDATE THERAPEUTICS
4/8/21
Mutiawati E, Fahriani M, Mamada SS, et al. | F1000Res
Aim: To determine the global prevalence of anosmia and dysgeusia in coronavirus disease 2019 (COVID-19) patients and to assess their association with severity and mortality of COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Peng HT, Rhind SG, Beckett A, et al. | JMIR Public Health Surveill
Aim: To characterize the latest advances and evidence in the use of CP for COVID-19 through a systematic review and quantitative analysis, identify knowledge gaps in this setting, and offer recommendations and directives for future research.
CANDIDATE THERAPEUTICS
4/8/21
Saragih ID, Saragih IS, Batubara SO, et al. | Geriatr Nurs
Aim: To systematically examine the association between dementia and mortality among older adults with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Rezaei S, Fatemi B, Majd ZK, et al. | Expert Rev Clin Immunol
Aim: To combine the results of clinical studies of different designs to investigate the efficacy and safety of tocilizumab in severely-to-critically ill COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
4/8/21
Islam MA, Kundu S, Alam SS, et al. | PLoS One
Aim: To conduct a systematic review and meta-analysis to estimate the overall pooled prevalence of fever and chills in addition to fever characteristics (low, medium, and high temperature) in both adult and paediatric COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Medina C, Chavira J, Aburto T, et al. | Salud Publica de Mexico
Aim: To describe the available evidence on the transmission of Covid-19 or similar acute respiratory infections in open, public spaces.
4/7/21
Sigahi TFAC, Kawasaki BC, Bolis I, et al. | Hum Factors Ergon Manuf
Aim: To investigate the impact of Covid?19 on work and workers of all occupations, reveal research gaps, and help managers to adapt to organizations amid the pandemic.
INFECTION CONTROL
4/7/21
Johnson H, Garg M, Shantikumar S, et al. | Turk J Urol
Aim: To evaluate the presence of virus in non-airborne body fluids as transmission vehicles.
INFECTION CONTROL
4/7/21
Saha S, Al-Rifai RH, Saha S | J Diabetes Metab Disord
Aim: To quantify the overall and subgroup weighted prevalence of mortality among diabetic (primary outcome) and non-diabetic (secondary outcome) and the weighted prevalence of DM (secondary outcome), in hospitalized COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/7/21
Zuin M, Rigatelli G, Bilato C, et al. | QJM
Aim: To perform a systematic review and meta-analysis of prevalence and mortality risk in COVID-19 patients with pre-existing dyslipidaemia.
CLINICAL CHARACTERISTICS
4/7/21
Camara AB, Brandao IA | Curr Med Chem
Aim: To study the receptor's family and functions most related to COVID-19 infection, also suggesting the tissue and cell location that the majority of COVID-19 receptors are mainly expressed.
CLINICAL CHARACTERISTICS
4/6/21
Kaur RJ, Dutta S, Bhardwaj P, et al. | Indian J Clin Biochem
Aim: To systematically review and synthesize the evidence on the safety data from the published COVID-19 vaccine trials.
INFECTION CONTROL
4/6/21
Sharma S, John R, Patel S, et al. | J Clin Orthop Trauma
Aim: To analyse the available evidence on bioaerosols in OSPs, and their significance in COVID-19 transmission.
INFECTION CONTROL
4/6/21
Alzahrani SH, Al-Rabia MW | Cardiol Res Pract
Aim: To assess the role of cardiac injury biomarkers measured on admission and during hospitalization as risk factors for subsequent death in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/6/21
Mardi P, Esmaeili M, Iravani P, et al. | Front Pediatr
Aim: To assess the demographic, laboratory, and clinical characteristics of children with KD-like syndrome during the COVID-19 pandemic and evaluate efficacy of treatments and patients' outcome. 
CLINICAL CHARACTERISTICS
4/6/21
Hoang T | Ann Glob Health
Aim: To examine the characteristics of repositive COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
4/6/21
Yan D, Zhang X, Chen C, et al. | Front Public Health
Aim: To comprehensively summarize the VST of SARS-CoV-2.
INFECTION CONTROL
4/6/21
Hariyanto TI, Kurniawan A | J Diabetes Metab Disord
Aim: To analyze the potential association between DPP-4 inhibitor and the composite poor outcome of COVID-19.
CLINICAL CHARACTERISTICS
4/6/21
Barzkar F, Ranjbar M, Sioofy-Khojine AB, et al. | Med J Islam Repub Iran
Aim: To synthesize current evidence systematically for in vitro, animal, and human studies on the efficacy and safety of chloroquine in patients with COVID-19.
CANDIDATE THERAPEUTICS
4/6/21
Eze P, Mezue KN, Nduka CU, et al. | Am J Cardiovasc Dis
Aim: To evaluate the efficacy and safety of CQ and HCQ in the treatment of COVID-19.
CANDIDATE THERAPEUTICS
4/6/21
Yan H, Ding Y, Guo W | Psychosom Med
Aim: To quantify the prevalence of the adverse mental health outcomes in medical staff working in the hospital settings during the COVID-19 pandemic and explore the relative distribution of anxiety and depressive symptoms.
UPDATED
MENTAL HEALTH
4/6/21
Zangiabadian M, Nejadghaderi SA, Zahmatkesh MM, et al. | Front Endocrinol
Aim: To summarize the available evidence on the potential mechanism of action and the efficacy of metformin in COVID-19 patients with DM.
CANDIDATE THERAPEUTICS
4/6/21
Kollias A, Kyrikoulis KG, Lagou S, et al. | Vasc Med
Aim: To review the current evidence regarding the prevalence of VTE in patients with COVID-19 screened/assessed with lower limb ultrasonography or computed tomography pulmonary angiography.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Mirbeyk M, Saghazadeh A, Rezaei N | Arch Gynecol Obstet
Aim: To review the evidence concerning pregnant women with confirmed COVID-19 and their neonates.
CLINICAL CHARACTERISTICS
4/5/21
Monroy-Fraustro D, Maldonado-Castellanos I, Aboites-Molina M, et al. | Front Public Health
Aim: To review articles on the effectiveness of bibliotherapy on different mental health problems.
MENTAL HEALTH
4/5/21
Kopanska M, Banas-Zabczyk A, Lagowska A, et al. | J Clin Med
Aim: To review the latest research on changes in EEG in patients with COVID-19 as a basis for further quantitative electroencephalogram (QEEG) diagnostics and EEG neurofeedback training. 
CLINICAL CHARACTERISTICS
4/5/21
Byambasuren O, Dobler CC, Bell K, et al. | PLoS One
Aim: To identify valid seroprevalence studies of SARS-CoV-2 infection and compare their estimates with the reported, and imputed, COVID-19 case rates within the same population at the same time point.
INFECTION CONTROL
4/5/21
Lee KW, Yap SF, Ngeow YF, et al.  | Int J Environ Res Public Health
Aim: To determine the epidemiological characteristics, clinical signs and symptoms, blood parameters, and clinical outcomes among PLHIV who contracted COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Chmielewska B, Barratt I, Townsend R, et al. | Lancet Glob Health
Aim: To assess the collective evidence on the effects on maternal, fetal, and neonatal outcomes of the pandemic.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Borkowska MJ, Jaguszewski MJ, Koda M, et al. | J Clin Med
Aim: To review the evidence on OHCA and whether bystander reluctance to perfrom CPR deteriorates OHCA outcomes in COVID-19 patients.
INFECTION CONTROL
4/5/21
Meherali S, Punjani N, Louie-Poon S, et al. | Int J Environ Res Public Health
Aim: To identify the impact of the pandemic on children's and adolescent's mental health and to evaluate the effectiveness of different interventions employed during previous and the current pandemic to promote children's and adolescents' mental health. 
UPDATED
MENTAL HEALTH
4/5/21
Kwok CS, Dashti M, Tafuro J, et al. | Ther Adv Infect Dis
Aim: To review the evidence on cleaning, disinfection or decontamination methods in the prevention of SARS-CoV-2.
INFECTION CONTROL
4/5/21
Li YC, Lai T, Lin S, et al. | Ther Adv Chronic Dis
Aim: To evaluate the influence of pre-existing CKD on risks of all-cause mortality, hospitalization, and critically ill condition among patients with COVID-19 infection.
UPDATED
4/5/21
Necho M, Tsehay M, Birkie M, et al. | Int J Soc Psychiatry
Aim: To summarize the existing data regarding anxiety, depression, and psychological distress during the covid-19 pandemic among the wider population so that effective intervention strategies will be initiated.
MENTAL HEALTH
4/5/21
Váncsa S, Dembrovsky F, Farkas N, et al.  | Viruses
Aim: To evaluate the clinical significance of repeatedly positive testing after coronavirus disease 2019 (COVID-19) recovery.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Lin W, Hung S, Lai C, et al. | Int Immunopharmacol
Aim: To investigate the clinical efficacy and safety of tocilizumab for treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/5/21
Wildwing T, Holt N | Ther Adv Chronic Dis
Aim: To summarize findings from a systematic overview of systematic reviews of the neurological symptoms seen in patients with COVID-19. 
CLINICAL CHARACTERISTICS
4/5/21
Zhao Y, Jin Y, Rao W, et al. | J Affect Disord
Aim: To compare the prevalence of psychiatric comorbidities in all subpopulations during the SARS and COVID-19 epidemics.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Marchi R, Sugita B, Centa A, et al. | Infect Genet Evol
Aim: To describe the role, function, and association of miRNAs in SARS-CoV-2 human infection and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Wang Z, Wang Y, Yang Z, et al. | Int J Infect Dis
Aim: To appraise the quality and availability of guidelines stated and whether non-invasive ventilation in the early stage of the pandemic is of importance.
UPDATED
CANDIDATE THERAPEUTICS
4/5/21
Gisondi P, Di Leo S, Bellinato F, et al. | Dermatol Ther
Aim: To systematically review the studies reporting the time of onset of selected skin lesions with respect to the reported onset of the COVID-19 core symptoms.
UPDATED
CLINICAL CHARACTERISTICS
4/4/21
Kow CS, Hasan SS | J Thromb Thrombolysis
Aim: To explore the overall effect of the use of antiplatelets in patients with COVID-19.
CANDIDATE THERAPEUTICS
4/3/21
Goodwin L, Hayward T, Krishan P, et al. | J Glob Health
Aim: To identify and integrate evidence from epidemiology, microbiology and fluid dynamics on the transmission of SARS-CoV-2 in indoor environments.
INFECTION CONTROL
4/2/21
Zhao Y, Zhao L, Yang X, et al. | Rev Cardiovasc Med
Aim: To find the association between COVID-19 and cardiovascular complications. 
CLINICAL CHARACTERISTICS
4/2/21
Jacob S, Hammed A, Lam V, et al. | ANZ J Surg
Aim: To assess the consistency of national and international surgical society recommendations regarding the choice of surgical approach; assess the quality of evidence of viral emission in surgical aerosol; and assess the quality of evidence comparing aerosol generation by different surgical energy devices.
UPDATED
INFECTION CONTROL
4/2/21
Ayers CK, Kondo KK, Williams BE, et al. | J Gen Intern Med
Aim: To understand disparities in H1N1 vaccine uptake by race/ethnicity, socioeconomic status (SES), rural/urban residence, population density, and disability status, and factors associated with unequal uptake, as well as the benefits and harms of interventions designed to attenuate inequities in H1N1 vaccine uptake
UPDATED
VA ESP
INFECTION CONTROL
4/2/21
Zhao M, Zhao C, Tu S, et al. | J Integr Med
Aim: To assess the methodological quality and variability in implementation of randomized controlled trials (RCTs) for treating COVID-19, and to analyze the support that should be provided to improve data collected during an urgent pandemic situation.
4/2/21
Abdelrahman Z, Liu Q, Jiang S, et al. | Front Pharmacol
Aim: To estimate the impact of current treatments on the efficacy and safety of COVID-19 by a meta-analysis.
UPDATED
CANDIDATE THERAPEUTICS
4/2/21
Dixit S, Nandakumar G | Rev Cardiovasc Med
Aim: To explore the possible role of technological advances and social media platforms as an alternate tool in promoting a healthy living style during the COVID-19 era.
MENTAL HEALTH
4/2/21
Upshaw TL, Brown C, Smith R, et al. | PLoS One
Aim: To review the early reports on the social determinants of COVID-19 infection, health service use and health outcomes.
UPDATED
INFECTION CONTROL
4/2/21
Groom LL, McCarthy MM, Stimpfel AW, et al. | J Am Med Dir Assoc
Aim: To further explore the modalities' ability to maximize access to specialty care, modernize care models, and improve patient outcomes.
INFECTION CONTROL
4/2/21
Zhang L, Hou J, Ma FZ, et al. | Arch Virol
Aim: To identify risk factors for COVID-19 severity and mortality. 
UPDATED
CLINICAL CHARACTERISTICS
4/1/21
Zhang X, Lewis AM, Moley JR | Sci Rep
Aim: To investigate the relationship between adverse COVID-19 outcomes and obesity.
CLINICAL CHARACTERISTICS
4/1/21
Baral R, Tsampasian V, Debski M, et al. | JAMA Netw Open
Aim: To conduct an updated and comprehensive systematic review and meta-analysis comparing mortality and severe adverse events (AEs) associated with receipt vs nonreceipt of ACEIs or ARBs among patients with COVID-19.
CLINICAL CHARACTERISTICS
4/1/21
Calzetta L, Ritondo BL, Coppola A, et al. | Vaccines
Aim: To identify the factors that may potentially influence the clinical efficacy of COVID-19 vaccines for which data from Phase III trials are currently available.
UPDATED
INFECTION CONTROL
4/1/21
Hilal N, Shaya R, Hamadeh R, et al. | Knowledge to Policy (K2P) Center
Aim: To review the evidence on the integration of COVID-19 vaccination into the services delivered by the National Primary Health Care network in Lebanon.
4/1/21
Shi Y, Guo M, Yang W, et al. | Expert Rev Vaccines
Aim: To investigate the impact of SARS-CoV-2 on neurodegenerative diseases and the latest developments in COVID-19 vaccines.
CLINICAL CHARACTERISTICS
4/1/21
Yassin A, Nawaiseh M, Shaban A, et al.  | BMC Neurol
Aim: To address the neurological aspects of COVID-19 including NM, NC, and ND findings.
UPDATED
CLINICAL CHARACTERISTICS
4/1/21
Carvalho APA, Conte-Junior CA | Glob Chall
Aim: To critically analyze nanomaterials? role as both a primary strategy (when the nanomaterials interact directly with the virus) and a secondary approach (when the nanomaterials improve the efficacy of another antiviral agent) against coronaviruses.
CANDIDATE THERAPEUTICS
4/1/21
Zakka K, Chidambaram S, Mansour S, et al. | Obes Surg
Aim: To evaluate the outcomes of COVID-19 patients suffering from obesity, and the effect of the COVID-19 pandemic on the obesity pandemic itself.
CLINICAL CHARACTERISTICS
4/1/21
Fathi M, Vakili K, Sayehmiri F, et al. | Iran J Immunol
Aim: To analyze the effectiveness of the measurement of specific antibodies to SARS-CoV2 (IgM and IgG) for the diagnosis of COVID-19 and to analyze the rate of SARS-CoV2 seroprevalence in the population.
DIAGNOSTICS
3/31/21
 | Health Information and Quality Authority
Aim: To explore potential populations for consideration in vaccine allocation group nine based on national and international evidence for the risk of infection, and risk of severe disease, with COVID-19.
3/31/21
Crawshaw J, Castillo G, Grimshaw J, et al. | The Ottawa Hospital Research Institute
Aim: To review the evidence on how behavioural science can help inform messaging to and broader supports for healthcare workers to encourage vaccination for COVID-19?
3/31/21
Kunzler AM, Rothke N, Gunthner L, et al. | Global Health
Aim: To assess its impact on mental health during the early phase by comparing pandemic with prepandemic data and to identify potential risk and protective factors.
UPDATED
MENTAL HEALTH
3/31/21
Choudhuri AH, Duggal S, Ahuja B, et al. | Indian J Med Microbiol
Aim: To address the efficacy and safety of HCQ in SARS CoV2 by overcoming the limitations of earlier meta-analysis.
CANDIDATE THERAPEUTICS
3/30/21
Marvaldi M, Mallet J, Dubertret C, et al. | Neurosci Biobehav Rev
Aim: To estimate the prevalence of anxiety, depression, trauma-related, and sleep disorders of healthcare workers during the COVID-19 pandemic.
MENTAL HEALTH
3/30/21
Khiabani K, Amirzade-Iranaq MH | Am J Infect Control
Aim: To conduct a systemic review and meta-analysis on the reliability and sensitivity of SARS-CoV-2 detection in saliva and deep throat sputum (DTS) compared to nasopharyngeal, combined naso/oropharyngeal, and oropharyngeal swabs.
DIAGNOSTICS
3/30/21
Tang K, Hsu B, Chen D | Front Immunol
Aim: To review the evidence on the autoimmune and rheumatic manifestations associated with COVID-19.
CLINICAL CHARACTERISTICS
3/30/21
Aski BH, Anari AM, Choobdar FA, et al. | Int J Cardiol Heart Vasc
Aim: To systematically assess the incidence of such cardiac abnormalities due to MIS-C in children suffering Covid-19.
CLINICAL CHARACTERISTICS
3/30/21
Papadopoulos V, Koutroulos MV, Zikoudi DG, et al. | Diabetol Int
Aim: To examine diabetes-related acute metabolic emergencies in COVID-19 patients
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Chou R, Dana T, Buckley D, et al. | Ann Intern Med
Aim: To examine the burden of SARS-CoV-2, SARS-CoV-1, and Middle Eastern respiratory syndrome (MERS)-CoV on HCWs and risk factors for infection, using rapid and living review methods.
UPDATED
WHO COLLABORATIVE
3/30/21
Chatterji G, Patel Y, Jain V, et al. | Indian J Orthop
Aim: To synthesize this published literature to give the orthopaedic fraternity an overview about the best practices that need to be followed during this period.
INFECTION CONTROL
3/30/21
Kaminska H, Szarpak L, Kosior D, et al. | Acta Diabetol
Aim: To summarize and synthesize the evidence published about the impact of diabetes mellitus on in-hospital mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/30/21
Peter HJ, Vancsa S, Ocskay K, et al. | Front Med
Aim: To evaluate if MAFLD or NAFLD are associated with a more severe disease course of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Vidale S | Cerebrovasc Dis
Aim: To describe the clinical features and etiological characteristics of ischemic stroke patients with CO-VID-19 infection.
CLINICAL CHARACTERISTICS
3/30/21
Iheanacho CO, Odili VU, Eze UIH | Futur J Pharm Sci
Aim: To systematically review available evidence for associations between exposure to RAAS inhibitors with susceptibility to SARS-CoV-2 infection and clinical outcomes in infected persons.
CLINICAL CHARACTERISTICS
3/30/21
Sucha D, van Hamersvelt RW, van den Hoven AF, et al. | Radiol Cardiothorac Imaging
Aim: To synthesize the literature on diagnostic test accuracy of chest radiography, CT, and US for the diagnosis of coronavirus disease 2019 (COVID-19) in patients suspected of having COVID-19 in a hospital setting and evaluate the extent of suboptimal reporting and risk of bias.
UPDATED
DIAGNOSTICS
3/30/21
Mahat RK, Panda S, Rathore V, et al. | Clin Epidemiol Glob Health
Aim: To evaluate the association of inflammatory parameters with the severity and mortality in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Monica AD, Ferrara P, Dal Mas F, et al. | Ann Ig
Aim: To analyze the literature on the impact of the Covid-19 crisis on the psychological well-being of health professionals.
MENTAL HEALTH
3/30/21
Bassatne A, Basbous M, Chakhtoura M, et al.  | Metabolism
Aim: To assess the impact of vitamin D status and supplementation on COVID-19 related mortality and health outcomes.
UPDATED
CANDIDATE THERAPEUTICS
3/30/21
Petrelli F, Luciani A, Perego G, et al. | J Steroid Biochem Mol Biol
Aim: To assess the association between vitamin D and risk, severity, and mortality for COVID-19 infection.
CLINICAL CHARACTERISTICS
3/29/21
Houlding E, Mate K, Engler K, et al. | JMIR Mhealth Uhealth
Aim: To present the range of RMTs used in delivering care to COVID-19 patients and identify perceived benefits and barriers for their use.
INFECTION CONTROL
3/29/21
Abeldano RA, Coca SM, Abeldano GF, et al. | Ther Adv Respir Dis
Aim: To assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection.
UPDATED
CANDIDATE THERAPEUTICS
3/29/21
Gabbai-Armelin PR, de Oliveira AB, Ferrisse TM, et al. | Eur J Clin Invest
Aim: To review the evidence on the relation of COVID-19 and thrombotic events and identify prognostic factors.
UPDATED
CLINICAL CHARACTERISTICS
3/29/21
Tuite AR, Fisman DN, Odutayo A, et al. | Ontario COVID-19 Science Advisory Table
Aim: What are the risks of COVID-19 hospitalization, ICU admission and death caused by VOCs as compared with the early variants of SARS-CoV-2?
3/29/21
Papotsi E, Giannakoulis VG, Xourgia E, et al.  | Crit Care
Aim: To investigate the effect (if any) of timing of intubation on clinical outcomes of critically ill patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
3/29/21
Nahshon C, Segev Y, Schmidt M, et al. | J Chemother
Aim: To review the evidence on the outcomes of diagnosed COVID-19 cancer patients.
CLINICAL CHARACTERISTICS
3/29/21
Diaz-Arocutipa C, Branez-Condorena A, Hernande AV | Pharmacoepidemiol Drug Saf
Aim: To assess the prevalence and risk of QTc prolongation and arrhythmic events in COVID-19 patients treated with these drugs.
CANDIDATE THERAPEUTICS
3/29/21
Emile S, Hamid HKS, Khan SM, et al. | J Gastrointest Surg
Aim: To assess the extent of adoption, efficacy, and safety of NOM of acute appendicitis in the setting of COVID-19.
UPDATED
INFECTION CONTROL
3/29/21
Li Y, Ashcroft T, Chung A, et al. | J Glob Health
Aim: To synthesise all available evidence regarding the risk factors for poor outcomes in hospitalised COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/29/21
Gratz J, Miegele M, Maleczek M, et al. | Front Med
Aim: To provide robust estimates of clinically relevant VTE incidence rates in adult critically ill patients with COVID-19 together with estimates of bleeding rates.
CLINICAL CHARACTERISTICS
3/29/21
Brolin K, Cenciarelli O, Colzani E, et al. | European Centre for Disease Prevention and Control
Aim: To provide a summary of the available scientific evidence on the risk of SARS-CoV-2 transmission to susceptible contacts from infected individuals with documented previous infection or vaccination.
3/29/21
Kow CS, Merchant HA, Mustafa ZU, et al. | Pharmacol Rep
Aim: To investigate the overall effect of ivermectin on the risk of mortality in patients with COVID-19.
CANDIDATE THERAPEUTICS
3/26/21
Cheng S, Zhao Y, Wang F, et al. | Medicine
Aim: To estimate the association of chronic comorbidities in severe and non-severe cases.
CLINICAL CHARACTERISTICS
3/26/21
Castiello T, Georgiopoulous G, Finocchiaro G, et al. | Heart Fail Rev
Aim: To review the challenges in the early diagnosis and management of myocarditis in patients with COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
3/26/21
Dubey P, Thakur B, Reddy S, et al. | BMC Pregnancy Childbirth
Aim: To review the evidence on any geographicaly differences in pregnant women with COVID-19.
CLINICAL CHARACTERISTICS
3/26/21
Johnson IG, Jones RJ, Gallagher JE, et al. | BDJ Open
Aim: To examine the literature relating to splatter, droplet settle and aerosol for periodontal procedures and forms part of a wider body of research to understand the risk of contamination in relation to periodontal care procedures relevant to COVID-19.
INFECTION CONTROL
3/26/21
Burns J, Movsisyan A, Stratil JM, et al. | Cochrane Database Syst Rev
Aim: To assess the effectiveness of travel?related control measures during the COVID?19 pandemic on infectious disease and screening?related outcomes.
UPDATED
WHO COLLABORATIVE
INFECTION CONTROL
3/26/21
Galanis P, Vraka I, Fragkou D, et al. | J Adv Nurs
Aim: To examine the impact of the COVID-19 pandemic on nurses’ burnout and to identify associated risk factors.
UPDATED
MENTAL HEALTH
3/26/21
Nugroho CW, Suryantror SD, Yuliasih Y, et al. | F1000Res
Aim: To research the risks and benefits of tocilizumab and investigate outcomes from different baseline criteria for administration of tocilizumab as a treatment for severe and critically ill COVID-19 patients.
CANDIDATE THERAPEUTICS
3/25/21
 | CADTH
3/25/21
Lai C, Chen C, Wang C, et al. | J Antimicrob Chemother
Aim: To provide updated information regarding the clinical efficacy of remdesivir in treating coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
3/25/21
Gerayeli FV, Milne S, Cheung C, et al. | EClinicalMedicine
Aim:  To determine whether COPD is a risk factor for poor outcomes in COVID-19, focusing on the specific endpoints of hospitalization, severe disease, and mortality.
UPDATED
CLINICAL CHARACTERISTICS
3/25/21
Antunes D, Lami M, Chukwudi A, et al. | Surgeon
Aim: To clarify whether inhalation of surgical smoke can increase the risk of COVID-19 infection.
INFECTION CONTROL
3/25/21
Kong X, Qi Y, Huang J, et al.  | Cancer Lett
Aim: To review the evidence on the prevalence of cancer in coronavirus disease 2019 (COVID-19)-infected patients and the severe illness incidence and mortality of COVID-19 patients with cancer.
UPDATED
CLINICAL CHARACTERISTICS
3/25/21
Hassanipour S, Azadbakht O, Dehnavi Z, et al. | Egypt J Radiol Nucl Med
Aim: To determine the correct location of chest CT scan in the diagnosis of COVID-19.
DIAGNOSTICS
3/25/21
 | Pan American Health Organization
Aim: To review the evidence on potential COVID-19 therapeutics.
3/25/21
Hayashi Y, Wagatsuma K, Nojima M, et al. | J Gastroenterol
Aim: To undertake a systematic review and meta-analysis to determine whether the presence of gastrointestinal (GI) symptoms contributed toward COVID-19 severity, and identify the GI symptoms characteristic of severe COVID-19.
CLINICAL CHARACTERISTICS
3/24/21
Kasemi A, Mohammadi V, Aghababaee SK, et al. | Adv Nutr
Aim: To summarize and clarify the evidence on the association between 25(OH)D concentrations and COVID-19 risk and outcomes.
UPDATED
CLINICAL CHARACTERISTICS
3/24/21
Ghaderzadeh M, Asadi F | J Healthc Eng
Aim: To provide an overview of the current state of all models for the detection and diagnosis of COVID-19 through radiology modalities and their processing based on deep learning. 
DIAGNOSTICS
3/24/21
Almufarrij I, Munro K | Int J Audiol
Aim: To systematically review the literature to December 2020, in order to provide a timely summary of evidence on SARS-CoV-2, COVID-19 and audio-vestibular symptoms.
UPDATED
CLINICAL CHARACTERISTICS
3/24/21
Longchamp G, Manzocchi-Besson S, Longchamp A, et al. | Thromb J
Aim: To systematically review and meta-analyze the risk of clinically relevant VTE in patients hospitalized for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/24/21
So M, Kabata H, Fukunaga K, et al. | BMC Pulm Med
Aim: To clarify the characteristics of radiological and functional lung sequelae of COVID-19 patients described in follow-up period.
CLINICAL CHARACTERISTICS
3/24/21
De Simone B, Chouillard E, Sartelli M, et al. | World J Emerg Surg
Aim: To provide evidence-based recommendations for the management of emergency surgical patients under COVID-19 pandemic for the safety of the patient and healthcare workers.
INFECTION CONTROL
3/24/21
Raju R, V P, Biatris PS, et al. | Futur J Pharm Sci
Aim: To analyze various trials registered across the globe providing an overall picture of the use of corticosteroids in the treatment of COVID-19.
CANDIDATE THERAPEUTICS
3/23/21
Artusi CA, Romagnolo A, Ledda C, et al. | J Parkinsons Dis
Aim: To assess whether the prevalence and outcome of COVID-19 in PD patients are different from those observed in the general population.
CLINICAL CHARACTERISTICS
3/23/21
Prasad M, Seth T, Elavarasi A | Indian J Hematol Blood Transfus
Aim: To study the efficacy and safety of convalescent plasma in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
3/23/21
Chenchula S, Ray A, Sadasivam B | Drug Res
Aim: To study all the available scientific evidence on famotidine research outcomes systematically to introspect its clinical efficacy and probable mechanisms and clinical efficacy against SARS-CoV-2.
CANDIDATE THERAPEUTICS
3/23/21
Peng J, Wang Q, Mei H, et al. | Aging
Aim: To investigate the association between fungal co-infection and mortality due to COVID-19.
CLINICAL CHARACTERISTICS
3/23/21
Masaeli N, Farhadi H | J Addict Dis
Aim: To find whether Internet-based addictive behaviors have increased during the pandemic and to define the main reasons for this increase.
MENTAL HEALTH
3/23/21
Kain D, Stall NM, Allen V, et al. | Science Table COVID-19 Advisory for Ontario
Aim: To review the evidence on routine asymptomatic screen testing of staff as a potential mitigating strategy to reduce SARS-CoV-2 introduction and transmission in LTC homes.
3/23/21
Tiruneh SA, Tesema ZT, Azanaw MM, et al. | Syst Rev
Aim: To assess the pooled incidence of COVID-19 complications and to identify the association between the incidence of complications and age.
UPDATED
CLINICAL CHARACTERISTICS
3/23/21
Teshome A, Adane A, Girma B, et al. | Front Public Health
Aim: To summarize the available evidence regarding the association between Vitamin D levels and the risk of COVID-19 infection.
CLINICAL CHARACTERISTICS
3/23/21
Ryan RE, Parkhill A, Schonfeld L, et al. | Health Evidence Network
Aim: To analyse evidence regarding communication with individuals and communities within the wider structural and sociopolitical context of the pandemic to support public health decision-makers when planning and implementing physical distancing measures.
WHO COLLABORATIVE
3/22/21
Menon T, Sharma R, Earthineni G, et al. | Cureus
Aim: To measure whether GI manifestations warrant the testing for SARS-CoV-2 alone or in combination with lung manifestations and the association of GI manifestations with severe disease and mortality. 
CLINICAL CHARACTERISTICS
3/22/21
Ssentongo P, Heilbrunn ES, Ssentongo A, et al. | Sci Rep
Aim: To conduct a systematic review and meta-analysis of the prevalence of HIV in patients hospitalized for COVID-19 and delineating clinical outcomes including mortality.
UPDATED
CLINICAL CHARACTERISTICS
3/22/21
Montazeri M, ZahediNasab R, Farahani A, et al. | JMIR Med Inform
Aim: To summarize information on the use of intelligent models for diagnosing and prognosing the COVID-19 to help early and timely diagnosis of the disease to help with health.
DIAGNOSTICS
3/22/21
Agarwal A, Fernando SM, Honarmand K, et al. | BMJ Open
Aim: To determine the risk of aerosol generation and associated transmission associated with nasopharyngeal and oropharyngeal swabs for detection of SARS-CoV-2.
INFECTION CONTROL
3/22/21
Zinellu A, Paliogiannis P, Carru C, et al. | Int J Infect Dis
Aim: To review the clinical implications of SAA concentrations in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/22/21
Dono F, Nucera B, Lanzone J, et al. | Epilepsy Behav
Aim: To summarize the available data on clinical features, diagnosis, and therapy of SE associated with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/22/21
Wei SQ, Bilodeau-Bertrand MB, Liu S, et al.  | CMAJ
Aim: To evaluate the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and adverse pregnancy outcomes.
CLINICAL CHARACTERISTICS
3/22/21
Zhao Y, Yin L, Jenil P, et al. | J Med Virol
Aim: To characterize inflammatory markers of MIS-C patients with COVID-19, Kawasaki disease (KD), and coronary artery abnormalities. 
UPDATED
CLINICAL CHARACTERISTICS
3/22/21
Barbalho SM, Matias JN, Flato UAP, et al. | Gastroenterology Res
Aim: To evaluate what influenza and COVID-19 may represent for patients with IBD.
CLINICAL CHARACTERISTICS
3/19/21
Welte T, Ambrose LJ, Sibbring GC, et al. | Eur Respir Rev
Aim: To identify clinical trials of pharmacological interventions for COVID-19 and evaluate for effectiveness.
UPDATED
CANDIDATE THERAPEUTICS
3/19/21
Zhang XM, Jiao J, Cao J, et al. | BMC Geriatr
Aim: To systematically review and quantify the results of the associations between frailty and mortality.
UPDATED
CLINICAL CHARACTERISTICS
3/19/21
Ghosn L, Chaimani A, Evrenoglou T, et al. | Cochrane Database Syst Rev
Aim: To assess the effect of IL?6 blocking agents compared to standard care alone or with placebo on efficacy and safety outcomes in COVID?19.
UPDATED
CANDIDATE THERAPEUTICS
3/18/21
Kalin A, Javid B, Knight M, et al. | Syst Rev
Aim: To summarise the literature on the performance of different rapid tests for exertional desaturation.
UPDATED
DIAGNOSTICS
3/18/21
Karimi L, Makvandi S, Vahedian-Azimi A, et al. | J Pregnancy
Aim: To investigate the effects of coronavirus disease 2019 (COVID-19) on mortality of pregnant and postpartum women.
CLINICAL CHARACTERISTICS
3/18/21
Moynihan R, Sanders S, Michaleff Z, et al.  | BMJ Open
Aim: To determine the extent and nature of changes in utilisation of healthcare services during COVID-19 pandemic. 
UPDATED
INFECTION CONTROL
3/18/21
Cares-Marambio K, Montenegro-Jimenez Y, Torres-Castro R, et al. | Chron Respir Dis
Aim: To determine the prevalence of respiratory symptoms in survivors of hospital admission after COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
3/18/21
Giovanella L, Ruggeri RM, Ovcaricek PP, et al. | Clin Transl Imaging
Aim: To assess the prevalence of thyroid dysfunction in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/18/21
Hassib M, Hamilton S, Elkhouly A, et al. | Cureus
Aim: To assess whether ACEi/ARB use in patients with COVID-19 conferred worsened severity of illness or increased mortality.
CLINICAL CHARACTERISTICS
3/18/21
Shi S, Wang F, Li J, et al. | IUBMB Life
Aim: To test the efficacy of CHM on digestive symptoms and liver function (primary outcomes), the aggravation of COVID-19 and the time to viral assay conversion (secondary outcomes), among patients with COVID-19, compared with standard pharmacotherapy.
CANDIDATE THERAPEUTICS
3/18/21
Kazemi E, Nejat RS, Ashkan F, et al. | Ann Clin Microbiol Antimicrobiol
Aim: To show the differences of laboratory findings of COVID-19 patients with different severity and survivability who had been admitted in hospital.
CLINICAL CHARACTERISTICS
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the AstraZeneca vaccine and blood clots.
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidenceo n the likelihood that SARS-CoV-2 will become endemic.
3/17/21
Grepin KA, Ho T, Liu Z, et al. | BMJ Glob Health
Aim: To review evidence of the effectiveness of travel measures implemented during the early stages of the COVID-19 pandemic in order to recommend change on how evidence is incorporated in the International Health Regulations (2005) (IHR).
UPDATED
INFECTION CONTROL
3/17/21
Lebrasseur A, Fortin-Bedard N, Lettre J, et al.  | JMIR Aging
Aim: To synthesize the existing research on the impact of the COVID-19 pandemic, and associated isolation and protective measures, on older adults. 
UPDATED
MENTAL HEALTH
3/17/21
Robinson E, Jones A, Lesser I, et al. | Vaccine
Aim: To address the current lack of consensus on; i) the proportion of the population willing to be vaccinated against COVID-19 when a vaccine become available and how this differs across countries, ii) whether vaccination intentions have declined as the pandemic has progressed, iii) socio-demographic inequalities in intended vaccine uptake.
UPDATED
INFECTION CONTROL
3/17/21
Wang Z, Wang D | Int J Soc Psychiatry
Aim: To reveal the law of formation of public psychological crisis in public health emergencies, and draw lessons from it.
MENTAL HEALTH
3/16/21
Kaur A, Setia AS, Kashyap A, et al. | Eur J Mol Clin Med
Aim: To highlight the existing literature and organize data associating the mortality of coronavirus disease 2019 (COVID-19) in patients with and without asthma.
CLINICAL CHARACTERISTICS
3/16/21
Meena JP, Gupta AK, Tanwar P, et al. | Pediatr Blood Cancer
Aim: To review the evidence on pediatric cancer patients affected by COVID-19 and analyze the clinical manifestations and outcomes.
UPDATED
3/16/21
Hariyanto TI, Halim DA, Jodhinata C, et al. | Clin Exp Pharmacol Physiol
Aim: To analyze the efficacy of colchicine administration and outcomes of COVID-19. 
CANDIDATE THERAPEUTICS
3/16/21
Dalia T, Lahan S, Ranka S, et al. | Indian Heart J
Aim: To delineate the influence of various cardiac conditions (especially CHF) on outcomes of patients with COVID-19 and to determine the prognostic value of cardiac biomarkers — Troponin I, Creatine Kinase-MB (CK-MB), and N-terminal-proB-type Natriuretic Peptide (NT-proBNP).
CLINICAL CHARACTERISTICS
3/16/21
Munich J, Dennett L, Swainson J, et al. | Front Psychiatry
Aim: To rapidly synthesize available data on emergency department utilization for psychiatric concerns during COVID-19.
3/16/21
Bokharee N, Khan YH, Khokhar A, et al. | Expert Rev Anti Infect Ther
Aim: To systematically analyze the published and ongoing studies evaluating the pharmacological interventions for COVID-19.
CANDIDATE THERAPEUTICS
3/16/21
Helvaci N, Eyupoglu ND, Karabulut E, et al.  | Front Endocrinol
Aim: To evaluate the prevalence of obesity in patients with COVID-19 and to stratify the estimates by illness severity.
UPDATED
3/16/21
Hossain A, Nasrullah SM, Tasnim Z, et al. | EClinicalMedicine
Aim: To estimate pooled seroprevalence of SARS-CoV-2 IgG antibodies across geographic regions and to investigate the pattern by age-group, gender, infection risk of HCWs, and study period.
UPDATED
3/16/21
da Silva FCT, Barbosa CP | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To understand the impact that COVID-19 is having on the front-line clinical team in the ICU environment, as well as reveal what proposals are being made to mitigate the clinical and psychological impacts that this group experiences.
3/15/21
Mehta AA, Haridas N, Belgundi P, et al. | Diabetes Metab Syndr
Aim: To provide a comprehensive summary of clinical and laboratory parameters that are associated with and indicative of increased severity among COVID-19 patients.
3/15/21
Marzoli F, Bortolami A, Pezzuto A, et al. | Sci Total Environ
Aim: To summarize all the evidence on surface survival of coronaviruses infecting humans. 
3/15/21
Lim ZJ, Reddy MP, Curtis JR, et al. | Crit Care Med
Aim: To investigate the incidence, characteristics, and outcomes of in-hospital cardiac arrest in patients with coronavirus disease 2019 and to describe the characteristics and outcomes for patients with in-hospital cardiac arrest within the ICU, compared with non-ICU patients with in-hospital cardiac arrest. 
UPDATED
3/15/21
Huntley B, Mulder IA, Di Mascio D, et al. | Obstet Gynecol
Aim: To compare the risk of intrauterine fetal death (20 weeks of gestation or later) and neonatal death among individuals who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with those who tested negative for SARS-CoV-2 on admission for delivery.
UPDATED
3/15/21
Mackey K, Arkhipova-Jenkins I, Armstrong C, et al. | Agency for Healthcare Research and Quality
Aim: To synthesize evidence on the prevalence, levels, and durability of the antibody response to SARS-CoV-2 infection among adults and how antibodies correlate with protective immunity.
CLINICAL CHARACTERISTICS
3/15/21
Karimian M, Azami M | Pol J Radiol
Aim: To evaluate CT scan findings of COVID-19 at the time of admission.
UPDATED
3/15/21
Allotey J, Stallings E, Bonet M, et al. | BMJ
Aim: To determine the clinical manifestations, risk factors, and maternal and perinatal outcomes in pregnant and recently pregnant women with suspected or confirmed coronavirus disease 2019 (covid-19).
UPDATED
CLINICAL CHARACTERISTICS
3/15/21
Yang Y, Sun S, Hu S, et al. | Front Psychol
Aim: To compare the different psychological interventions and distinguish the most effective way to treat psychological crisis according to different clinical manifestations in people affected by coronavirus disease 2019 (COVID-19).
3/15/21
Zhang X, Xi L, Pang F, et al. | Iran J Public Health
Aim: To summarize the clinical evidence regarding the efficacy and safety of convalescent plasma therapy in the treatment of severe COVID-19.
3/15/21
Qiang Z, Wang B, Garrett BC, et al. | Curr Opin Cardiol
Aim: To have a greater mortality impact on subgroups of people in the population who are deemed to be at higher medical disease risk.
3/15/21
Pranata R, Huang I, Lim MA, et al. | Arch Gerontol Geriatr
Aim: To establish the association between delirium and mortality in older adults with COVID-19.
UPDATED
3/15/21
Xing K, Tu X, Liu M, et al. | Zhongguo Dang Dai Er Ke Za Zhi
Aim: To evaluate systematically the efficacy and safety of COVID-19 vaccines.
3/15/21
Abate SM, Checkol YA, Mantefardo B | Ann Med Surg
Aim: To provide global evidence on the prevalence and risk factors including age, gender, comorbidity, and substance use on hospital mortality among hospitalized patients with COVID-19.
3/15/21
Syahrul S, Maliga HA, Ilmawan M, et al. | F1000Research
Aim: To determine the global prevalence, chronological order of symptom appearance, and mortality rates with regard to hemorrhagic and ischemic stroke in patients with coronavirus disease 2019 (COVID-19) and to discuss possible pathogeneses of hemorrhagic and ischemic stroke in individuals with the disease.
UPDATED
3/15/21
Juul S, Nielsen N, Feinberg J, et al. | PLoS Med
Aim: To compare the effects of all treatment interventions for participants in all age groups with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
3/15/21
Yuan J, Qian H, Cao S, et al. | Transl Pediatr
Aim: To investigate the clinical features of pregnant women and their neonates with coronavirus disease 2019 (COVID-19) and the evidence of vertical transmission of COVID-19.
3/15/21
Moran C, Campbell DJT, Campbell TS, et al. | J Public Health
Aim: To identify predictors of attitudes toward and adherence to COVID-19 public health guidelines, and identify interventions aiming to improve adherence.
3/15/21
Alene M, Yismaw L, Assemie MA, et al. | BMC Infect Dis
Aim: To determine the overall pooled mean serial interval and incubation period of COVID-19 using available evidences.
3/15/21
Dorward J, Gbinigie O, Cai T, et al. | Antivir Ther
Aim: To synthesise the clinical evidence for lopinavir/ritonavir as a treatment for COVID-19.
3/15/21
Stanoeva KR, van der Eijk AA, Meijer A, et al. | Euro Surveill
Aim: To review current published knowledge on the kinetics of SARS-CoV-2 infection as assessed by RNA molecular detection in a wide range of clinical samples.
3/12/21
Oltean I, Tran J, Lawrence S, et al. | Heliyon
Aim: To illustrate findings in a narrative fashion pertaining to SARS-CoV-2 on placental pathology, maternal, and neonatal outcomes.
UPDATED
CLINICAL CHARACTERISTICS
3/12/21
Jafari A, Mohammadpour M, Chanbarzadegan A, et al. | J Educ Health Promot
Aim: To review the literature to provide a better understanding of the status of dentists and other oral health practitioners' knowledge, attitude, and awareness about COVID-19.
INFECTION CONTROL
3/12/21
Sharma D, Sharma N, Sharma P, et al. | J Educ Health Promot
Aim: To discuss about investigational new as well as repurposed drugs currently under trial for COVID-19 infection.
CANDIDATE THERAPEUTICS
3/11/21
Pellicori P, Doolub G, Wong CM, et al. | Cochrane Database Syst Rev
Aim: To assess the prevalence of pre?existing cardiovascular comorbidities associated with suspected or confirmed cases of COVID?19 in a variety of settings, including the community, care homes and hospitals. 
UPDATED
CLINICAL CHARACTERISTICS
3/11/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the effectiveness of the AstraZeneca vaccine, particuarly regarding hospitalisations in the United Kingdom.
3/11/21
Alkhathami M, Advani SM, Abalkhail AA, et al. | Lung India
Aim: To determine the prelavence and mortality of chronic lung diseases which include COPD, lung cancer, asthma, and cystic fibrosis in confirmed COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
3/11/21
Wang Q, Liu J, Shao R, et al.  | Rheumatol Int
Aim: To integrate data on the epidemiology of COVID-19 in the RD population and to analyze the risk of COVID-19 infection and its complications in RD patients compared with the general population.
UPDATED
CLINICAL CHARACTERISTICS
3/11/21
Cruciani F, Amato L, De Crescenzo F, et al. | Recenti Prog Med
Aim: To synthesize and evaluate the quality of evidence of efficacy and safety for the treatment. 
CANDIDATE THERAPEUTICS
3/10/21
Kumar P, Jindal K, Aggarwal S, et al. | Indian J Orthop
Aim: To ascertain the impact of a co-existent infection on the 30-day mortality and inpatient mortality of patients with hip fractures including neck femur, intertrochanteric and subtrochanteric fractures. 
CLINICAL CHARACTERISTICS
3/10/21
Osman M, Klopfenstein T, Belfeki N, et al. | Viruses
Aim: To compare the clinical features and outcome, laboratory, and radiological findings of COVID-19 patients with influenza adult patients.
CLINICAL CHARACTERISTICS
3/10/21
Cai J, Tang M, Gao Y, et al. | Front Med
Aim: To determine which mode of delivery is better for preventing possible vertical transmission from COVID-19 positive pregnant women to the neonate.
UPDATED
INFECTION CONTROL
3/10/21
Pal R, Banerjee M, Mukherjee S, et al. | Ther Adv Endocrinol Metab
Aim: To provide a precise summary of the effect of DPP4i use (preadmission or in-hospital) and mortality in COVID-19 patients with diabetes mellitus (DM).
UPDATED
CLINICAL CHARACTERISTICS
3/10/21
Meena J, Jain S, Kumar j, et al.  | J Infect Chemother
Aim: To systematically synthesize the evidence over the efficacy and safety of HCQ or CQ alone as compared to placebo or no active intervention in adults with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
3/10/21
Hashan MR, Smoll N, King C, et al. | EClinicalMedicine
Aim: To define the epidemiology of COVID-19 outbreaks in RACFs to estimate the epidemiological index of the disease for these vulnerable populations.
UPDATED
CLINICAL CHARACTERISTICS
3/10/21
Gawronska K, Lorkowski J | Geriatr Orthop Surg Rehabil
Aim: To present the possible correlation between COVID-19 and diseases of the musculoskeletal system, in particular the occurrence of fall-related injuries.
CLINICAL CHARACTERISTICS
3/10/21
SeyedAlinaghi S, Afsahi AM, MohsseniPour M, et al. | Arch Acad Emerg Med
Aim: To investigate the available evidence for long-term complications of COVID-19.
CLINICAL CHARACTERISTICS
3/10/21
Chou R, Dana T, Jungbauer R, et al. | Ann Intern Med
Aim: To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.
UPDATED
3/10/21
Li Y, Scherer N, Felix L, et al. | PLoS ONE
Aim: To provide updated estimates of the prevalence of depression, anxiety and post-traumatic stress disorder (PTSD) among health care workers during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/10/21
Xia L, Chen C, Liu Z, et al. | Front Psychiatry
Aim: To explore the prevalence of sleep disturbances and sleep quality in Chinese HWs during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/10/21
Gallastegui N, Zhou JY, von Drygalski A, et al. | Clin Appl Thromb Hermost
Aim: To estimate the incidence of PE during hospitalization for COVID19 within and outside ICUs.
CLINICAL CHARACTERISTICS
3/9/21
Piquero AR, Jennings WG, Jemison E, et al. | J Crim Justice
Aim: To estimate the effect of COVID-19-related restrictions (i.e., stay at home orders, lockdown orders) on reported incidents of domestic violence.
MENTAL HEALTH
3/9/21
Veazie S, O'Neil M, LaFavor B, et al.  | VA Evidence Synthesis Program
Aim: To compare the prevalence of mental health disorders among adults who have been hospitalized for COVID-19 to relevant comparison groups, assess whether the prevalence of mental health disorders varies by patient and disease characteristics, and ascertain mental health care utilization and resource needs for adults following hospitalization for COVID-19.
UPDATED
VA ESP
MENTAL HEALTH
3/9/21
Deng J, Zhou F, Hou W, et al. | Psychiatry Res
Aim: To examine the prevalence of depressive symptoms, anxiety symptoms, and sleep disturbances in higher education students to better understand the impact of the COVID-19 pandemic on the mental health of higher education students.
UPDATED
MENTAL HEALTH
3/8/21
Ho TC, Wang YH, Chen YL | Pathogens
Aim: To synthesize articles regarding the cure of COVID-19 by CQ or HCQ and depict the efficacy of these drugs for COVID-19 treatment.
CANDIDATE THERAPEUTICS
3/8/21
Macedo A, Gonçalves N, Febra C, et al. | Ann Epidemiol
Aim: To evaluate the mortality of COVID-19.
CLINICAL CHARACTERISTICS
3/8/21
DiLorenzo MA, O'Connor S, Ezekwesili C, et al. | Int J Gynaecol Obstet
Aim: To summarize recommendations for three areas of maternal and fetal care - breastfeeding, post-partum social distancing, and decontamination.
INFECTION CONTROL
3/8/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the impact of the COVID-19 pandemic on the publication of pre-peer review articles and the quality of research evidence.
3/8/21
Peddapalli A, Gehani M, Kalle AM, et al. | Viruses
Aim: To review various mechanisms of excess immune response in adult COVID-19 patients
CLINICAL CHARACTERISTICS
3/8/21
Moreira VM, Mascarenhas P, Machado V, et al. | Diagnostics
Aim: To compare the overall accuracy of nucleic acid assays run with index specimens (saliva, deep-throat saliva/posterior oral samples (DTS/POS], sputum, urine, feces, and tears/CS), against standard NPS/OPS based test results.
DIAGNOSTICS
3/8/21
Johnson T, Bishoff T, Kremsreiter K, et al. | Med J
Aim: To perform a systematic review of the literature and to provide evidence-based algorithms for diagnosing or ruling out COVID-19.
DIAGNOSTICS
3/8/21
Sarma P, Bhattacharyya A, Kaur H, et al. | Indian J Pharmacol
Aim: To evaluate the efficacy and safety of steroid therapy among all severity categories of patients with COVID-19 (mild to moderate and severe to critical category) in terms of "mortality," "requirement of mechanical ventilation," "requirement of ICU" and clinical cure parameters.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Shehab M, Alrashed F, Shuaibi S, et al. | BMJ Open Gastroenterol
Aim: To evaluate the prevalence of GI, liver function test (LFT) abnormalities, and mortality of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Boldt K, Coenen M, Movsisyan A, et al. | Int J Environ Res Public Health
Aim: To identify interventions that target children, their caregivers and/or families, in order to reduce the psychosocial impacts caused by the COVID-19 and comparable disease outbreaks, as well as associated control measures (e.g., quarantine).
MENTAL HEALTH
3/8/21
Cordeiro LP, Linhares EONN, Nogueira FGO, et al. | Pharmacol Rep
Aim: To systematically review the studies that described the use of GC in patients with COVID-19 and to provide a safer analysis of the effectiveness and recommendations for GC use.
CANDIDATE THERAPEUTICS
3/8/21
Booth A, Reed AB, Ponzo S, et al. | PLoS One
Aim: To systematically map all the available evidence on the association of various clinical, demographic, and lifestyle variables with the risk of specific adverse outcomes in patients with COVID?19.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Sansone P, Giaccari LG, Aurilio C, et al. | Life
Aim: To give a comprehensive overview of the demographic characteristics, clinical features, diagnostic investigations, and outcome of SARS-CoV-2-related GBS patients. 
CLINICAL CHARACTERISTICS
3/8/21
Al Falasi B, Al Mazrouei M, Al Ali M, et al. | Int J Environ Res Public Health
Aim: To investigate the prevalence and determinants of immediate and long-term post-traumatic stress disorder (PTSD) effects on healthcare professionals by the COVID-19 (SARS CoV-2) and SARS-2003 (SARS CoV-1) pandemics.
MENTAL HEALTH
3/8/21
Jamshidi P, Hajikhani B, Mirsaeidi M, et al. | Front Med
Aim: To investigate the prevalence and characteristics of cutaneous manifestations in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Skapetis T, Law C, Rodricks R, et al. | BMC Med Ethics
Aim: To determine the ethical challenges associated with conducting medical research in low COVID-19 prevalence countries.
3/8/21
Wibowo A, Pranata R, Akbar MR, et al. | Int J Infect Dis
Aim: To assess the prognostic value of elevated troponin above the 99th percentile upper reference limit (URL) on mortality and factors affecting their relationship.
CLINICAL CHARACTERISTICS
3/8/21
Akbar MR, Pranata R, Wibowo A, et al. | Diabetes Metab Syndr
Aim: To evaluate the association between the elevated CK and severity and mortality in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/7/21
Tondas AE, Mulawarman R, Trifitriana M, et al. | J Infect Dev Ctries
Aim: To investigate the electrocardiographic (ECG) ventricular repolarization indices in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/6/21
Li Z, Li X, Shen J, et al. | Environ Sci Pollut Res Int
Aim: To systematically review case reports on COVID-19-associated MFS, including the electrophysiological and clinical phenotypes.
CLINICAL CHARACTERISTICS
3/5/21
Sinclair JE, Zhu Y, Xu G, et al. | iScience
Aim: To analyze the association of host co-morbidities (chronic respiratory illnesses, cardiovascular disease [CVD], hypertension or diabetes mellitus [DM]) with the acute cardiovascular complications associated with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
3/5/21
Vahedian-Azimi A, Karimi L, Makvandi S, et al. | Adv Exp Med Biol
Aim: To investigate whether the causative agent of COVID-19 is found in semen. 
CLINICAL CHARACTERISTICS
3/5/21
Zhan Y, Shang J, Gu Y, et al. | J Med Virol
Aim: To evaluate the efficacy of corticosteroids on COVID-19 patients with different levels of disease severity.
CANDIDATE THERAPEUTICS
3/5/21
Schumm MA, Hadaya JE, Mody N, et al. | JAMA
Aim: To perform a systematic review to evaluate the evidence on effectiveness and feasibility of different processes used for decontaminating N95 respirators.
INFECTION CONTROL
3/5/21
Sheth A, Modi M, Dawson D, et al. | Sci Rep
Aim: To summarize the evidence regarding the prognostic relevance of cardiac biomarkers from data available in published reports.
CLINICAL CHARACTERISTICS
3/5/21
Makvandi S, Mahdavian M, Kazemi-Nia G, et al. | Adv Exp Med Biol
Aim: To report clinical symptoms, laboratory findings, and obstetrical complications, maternal, fetal, and neonatal complications of COVID-19 infection in pregnant women.
CLINICAL CHARACTERISTICS
3/5/21
Heidari-Beni F, Vahedian-Azimi A, Shojaei S, et al. | Adv Exp Med Biol
Aim: To investigate PCT levels in severe COVID-19 patients.
CLINICAL CHARACTERISTICS
3/5/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on how long the COVID-19 virus can survive with potential for infection on surfaces found in community settings.
3/4/21
Strudwick G, Sockalingam S, Kassam I, et al. | JMIR Ment Health
Aim: To identify digital interventions that could be used to support the mental health of the Canadian general population during the COVID-19 pandemic. 
MENTAL HEALTH
3/4/21
Park JY, Freer R, Stevens R, et al.  | Oxford COVID-19 Evidence Service
3/4/21
Yang Y, Luo K, Jiang Y, et al. | J Nutr Health Aging
Aim: To synthesize the current studies to investigate impact of frailty on COVID-19 outcomes and provide evidence-based decisions in clinical practice.
CLINICAL CHARACTERISTICS
3/3/21
Jones EAK, Mitra AK, Bhuiyan AR | Int J Environ Res Public Health
Aim: To assess the impact of the COVID-19 pandemic on adolescent mental health.
MENTAL HEALTH
3/2/21
Simons D, Shahab L, Brown J, et al. | Addiction
Aim: To estimate the association of smoking status with rates of i) infection, ii) hospitalisation, iii) disease severity, and iv) mortality from SARS?CoV?2/COVID?19 disease.
UPDATED
CLINICAL CHARACTERISTICS
3/1/21
Raphael J, Winter R, Berry K | BJPsych Open
Aim: To explores service adaptations in mental health services during the COVID-19 pandemic and other contagions.
INFECTION CONTROL
3/1/21
Diallo A, Carlos-Bolumbu M, Traore M, et al. | J Public Health Res
Aim: To compare and rank the efficacy and safety of treatments tested in patients with SARSCoV- 2 virus.
UPDATED
CANDIDATE THERAPEUTICS
3/1/21
Janiaud P, Axfors C, Schmitt AM, et al. | JAMA
Aim: To assess clinical outcomes with convalescent plasma treatment vs placebo or standard of care in peer-reviewed and preprint publications or press releases of randomized clinical trials (RCTs).
CANDIDATE THERAPEUTICS
3/1/21
Sahranavard M, Rezayat AA, Bidary MZ, et al. | Arch Iran Med
Aim: To review the evidence on cardiac complications in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/1/21
Liang C, Zhang W, Li S, et al. | Med Clin
Aim: To search the association between coronary heart disease and the prognosis of COVID-19 patients.
CLINICAL CHARACTERISTICS
3/1/21
Willi S, Luthold R, Hunt A, et al. | Travel Med Infect Dis
Aim: To evaluate the available evidence of all intermediate and long-term COVID-19 sequelae affecting formerly healthy adults.
CLINICAL CHARACTERISTICS
3/1/21
Toba N, Gupta S, Ali AY, et al. | Pediatr Pulmonol
Aim: To understand the clinical characteristics of COVID-19 in children.
CLINICAL CHARACTERISTICS
3/1/21
Zhou X, Pu Y, Zhang D, et al. | Acta Radiol
Aim: To explore the chest CT findings and dynamic CT changes of COVID-19 using systematic evaluation methods, instructing the clinical imaging diagnosis.
DIAGNOSTICS
3/1/21
Yang L, Chai P, Yu J, et al. | Cancer Biol Med
Aim: To investigate cancer incidence in patients with COVID-19 and to determine whether cancer was associated with mortality among patients with COVID-19.
CLINICAL CHARACTERISTICS
3/1/21
Gupta N, Balcom S, Gulliver A, et al. | Int J Health Planning Manag
Aim: To assess the state of the evidence on policy and planning responses to HRH surge capacity during the coronavirus disease (COVID?19) pandemic and other viral respiratory disease outbreaks of global significance in the 21st century.
UPDATED
3/1/21
Zang S, Han X, Cui Q, et al. | Transl Pediatr
Aim: To summarize a comprehensive review and meta-analysis with a complete evaluation of CT characteristics in pediatric COVID-19 cases. 
UPDATED
DIAGNOSTICS
3/1/21
Samadder S | Front Public Health
Aim: To identify the possible cause of secondary pneumonia infection observed in COVID-19 patients.
CLINICAL CHARACTERISTICS
3/1/21
Tassone D, Thompson A, Connell W, et al. | Intern Med J
Aim: To determine whether immunosuppressed patients are at higher risk of COVID-19 to help inform the management of patients receiving immunosuppressant therapies during the pandemic.
CLINICAL CHARACTERISTICS
3/1/21
Zhou X, Cheng Z, Luo L, et al. | Thromb Res
Aim: To evaluate the prevalence of disseminated intravascular coagulation (DIC) in COVID-19 patients and to determine the association of DIC with the severity and prognosis of COVID-19.
CLINICAL CHARACTERISTICS
3/1/21
Fan FC, Zhang SY, Cheng Y | J Epidemiol Community Health
Aim: To evaluate the updated psychological prevalence of COVID-19 and historical coronavirus-related data.
MENTAL HEALTH
3/1/21
Tang Y, Li W, Baskota M, et al. | Transl Pediatr
Aim: To describe the clinical features, treatment and outcomes of MIS-C, as well as to assess the risk of bias of published case studies, analyzing their reporting quality.
CLINICAL CHARACTERISTICS
3/1/21
Poly TN, Islam M, Yang HC, et al. | Front Med
Aim: To evaluate the effect of obesity, associated comorbidities, and other factors on the risk of death due to COVID-19. 
CLINICAL CHARACTERISTICS
3/1/21
Aghili SMM, Ebrahimpur M, Arjmand B, et al. | Int J Obes
Aim: To clarify the obesity relationship with COVID-19 severity, comorbidities, and discussing possible mechanisms.
CLINICAL CHARACTERISTICS
3/1/21
Goodwin VA, Allan L, Bethel A, et al. | Physiotherapy
Aim: To establish the evidence for rehabilitation interventions tested in populations of patients admitted to ICU and critical care with severe respiratory illness, and consider whether the evidence is generalizable to patients with COVID-19.
CANDIDATE THERAPEUTICS
3/1/21
Singh AK, Jena A, Kumar-M P, et al. | United European Gastroenterol J
Aim: To investigate the risk of the acquisition of SARS-CoV-2 in patients with IBD, and to estimate whether the drugs affect the risk of acquisition and outcomes of SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
3/1/21
Canete MG, Valenzuela IM, Garces PC, et al. | Oral Surg Oral Med Oral Pathol Oral Radiol
Aim: To describe the value of saliva as a noninvasive sample for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in comparison with the current method for sample collection, the nasopharyngeal swab.
DIAGNOSTICS
3/1/21
Barlow-Pay F, Htut TW, Khezrian M, et al. | Ther Adv Drug Saf
Aim: To summarize the current international clinical guidelines to highlight areas where research is needed through critical appraisal of the evidence base of these guidelines.
CLINICAL CHARACTERISTICS
3/1/21
Alom S, Chiu CM, Jha A, et al. | Cancer Control
Aim: To gather primary data from cancer institutions that have implemented changes to cancer service provision amid the COVID-19 outbreak to inform future intervention and health care facility response strategies. 
INFECTION CONTROL
3/1/21
Naveed H, Elshafeey A, Al-Ali D, et al. | J Clin Pharmcol
Aim: To compare specific blood markers in both groups of COVID-19 patients in order to gain a better insight into the interaction of ACEi/ARBs with the different body functions during the infection.
CLINICAL CHARACTERISTICS
3/1/21
Morris AM, Stall NM, Bobos P, et al. | Ontario COVID-19 Science Advisory Table
Aim: Does tocilizumab improve patient outcomes such as mortality, need for mechanical ventilation, requirement for organ support, intensive care unit (ICU) length of stay, and hospital length of stay for individuals hospitalized with COVID-19? 
3/1/21
Sabe M, Dorsaz O, Hugguelet P, et al. | Gen Hosp Psychiatry
Aim: To review clinical evidence regarding the potential toxicity/side effects of psychiatric medications in the context of SARS-CoV-2 infection.
CANDIDATE THERAPEUTICS
2/28/21
Karruli A, Spiezia S, Boccia F, et al. | Transpl Infect Dis
Aim: To assess the effect of continuing immune suppressive therapy in solid organ transplant recipients (SOTR) with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/28/21
 | Penn Medicine’s Center for Evidence-based Practice
Aim: To identify pathways, algorithms, and clinical risk prediction tools that can be used in Emergency Department triage of patients with suspected or confirmed COVID-19 disease and to review the evidence on their effectiveness.
2/26/21
Tan BK, Mainbourg S, Friggeri A, et al. | Thorax
Aim: To review the evidence on the prevalence of venous thromboembolic event (VTE) and arterial thromboembolic event (ATE) thromboembolic events in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/26/21
Liang S, Zhang Y, Shen C, et al. | Front Pharmacol
Aim: To further probe the role of CHM used with or without conventional western therapy on the treatment of COVID-19.
CANDIDATE THERAPEUTICS
2/26/21
Ernawati K, Cantika IB, Isaputri RR, et al. | Int J Public Health Sci
Aim: To determine the community's knowledge, attitudes, and behavior in preventing the transmission of COVID-19.
INFECTION CONTROL
2/26/21
Aibakr AA, Ingle NA, Assery MK, et al. | Ann Med Health Sci Res
Aim: To identify the role of corticosteroids on coronavirus infection and to compare the mortality and morbidity rate of steroid intervened corona virus infected patients.
CANDIDATE THERAPEUTICS
2/26/21
Sun C, Chen Y, Hu L, et al.  | Dig Dis Sci
Aim: To assess effects of famotidine on improving the outcome of those suffered COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
2/26/21
Mishra P, Parveen R, Bajpai R, et al. | Ann Acad Med Singap
Aim: To find the probable association between cardiovascular disease with disease severity and mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/26/21
Bentivegna M, Hulme C, Ebell MH | J Am Board Fam Med
Aim: To summarize the best available evidence regarding individual risk factors, simple risk scores, and multivariate models that use patient characteristics, vital signs, comorbidities, and laboratory tests in inpatients.
UPDATED
CLINICAL CHARACTERISTICS
2/26/21
Benzinger P, Kuru S, Keilhauer A, et al. | Z Gerontol Geriatr
Aim: To review the evidence on the psychosocial effects of the COVID-19 pandemic on residents, visitors, and employees of elderly care facilities.
MENTAL HEALTH
2/26/21
Hurtado-Diaz M, de la Cruz JC, Blanco-Munoz J, et al. | Salud Publica de Mexico
Aim: To summarize and analyze the evidence of the association between Covid-19 and climatic factors. 
CLINICAL CHARACTERISTICS
2/25/21
Zhang H, Ma S, Han T, et al. | Eur J Integr Med
Aim: To review the evidence on the influence of smoking history on the severe and critical outcomes on people with COVID-19 pneumonia.
CLINICAL CHARACTERISTICS
2/25/21
McAlpine LS, Fesharaki-Zadeh A, Spusich S | Curr Opin Psychiatry
Aim: To review the outcomes in patients with COVID-19 and NDD.
CLINICAL CHARACTERISTICS
2/25/21
Yin TX, Li Y, Ying Y, et al. | BMC Infect Dis
Aim: To provide systematic evaluation and detailed estimation of prevalence rates of different kinds of common comorbidities in severe and non-severe COVID-19 patients and tries to illustrate the outcomes by combination with underlying pathogenesis to better understand how basic diseases contribute to the aggravation of SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
2/25/21
Struyf T, Deeks JJ, Dinnes J et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of signs and symptoms to determine if a person presenting in primary care or to hospital outpatient settings, such as the emergency department or dedicated COVID?19 clinics, has COVID?19 disease or COVID?19 pneumonia.
UPDATED
DIAGNOSTICS
2/25/21
Ng JJ, Liang ZC, Choong A | J Intensive Care
Aim: To quantitatively synthesize available literature by using meta-analysis of proportions to estimate the weighted average incidence of PTE in critically ill COVID-19 patients admitted to the intensive care unit (ICU).
UPDATED
CLINICAL CHARACTERISTICS
2/25/21
Schiff JW | CMH Initiative
2/24/21
Jamebozorgi AH, Agoush L, NooriHekmat S, et al. | Research Square
Aim: To systematically review the challenges and prerequisites, strategies, and measures related to the retention of health workers during the disaster.
MENTAL HEALTH
2/24/21
Corona G, Pizzocaro A, Vena W, et al. | Rev Endocr Metab Disord
Aim: To provide an overview and a meta-analysis of main predictors and of country differences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-associated mortality rate (MR) in hospitalized patients. 
UPDATED
CLINICAL CHARACTERISTICS
2/24/21
Ma S, Xu C, Liu S, et al. | Signal Transduct Target Ther
Aim: To address the efficacy and safety of corticosteroids among severe COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/24/21
Widyadharma IPE, Hendellyn A, Dewi A | Egypt J Neurol Psychiatr Neurosurg
Aim: To briefly review neurologic manifestation in COVID-19 infection in the Asia region (South East Asia and the Western Pacific Region).
CLINICAL CHARACTERISTICS
2/24/21
Bulfone TC, Malekinejad M, Rutherford GW, et al. | J Infect Dis
Aim: To quantify the risk of SAR-CoV-2 transmission in outdoor settings. 
UPDATED
INFECTION CONTROL
2/24/21
Martins MM, Prata-Barbosa A, da Cunha AJLA | Paediatr Int Child Health
Aim: To review the evidence on clinical presentations, ways of transmission, severity and prognosis of SARS-CoV-2 infection in children and adolescents.
CLINICAL CHARACTERISTICS
2/23/21
Avianai JK, Halim D, Soeroto AY, et al. | Rev Med Virol
Aim: To evaluate CPT potentials in COVID-19 treatment, by performing systematic review and meta-analysis of studies in COVID-19 and other similar viral respiratory diseases, including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS) and Influenza.
UPDATED
CANDIDATE THERAPEUTICS
2/23/21
 | CADTH
Aim: To review the evidence on tocilizumab and sarilumab for their potential use in managing COVID-19.
2/22/21
Conrado PCV, Sakita KM, Arita GS, et al. | Photodiagnosis Photodyn Ther
Aim: To assess whether photodynamic therapy and its mechanisms of action could be effective in inactivating SARS-CoV-2.
CANDIDATE THERAPEUTICS
2/22/21
Soheili M, Moradi G, Baradaran HR, et al. | J Matern Fetal Neonatal Med
Aim: To find out whether COVID-19 may cause different manifestations and outcomes in the antepartum and postpartum period or not.
CLINICAL CHARACTERISTICS
2/22/21
Koeppen M, Rosenberger P, Magunia H | Clin Med Insights Circ Respir Pulm Med
Aim: To assess the prevalence of cardiovascular comorbidities and complications in ICU-admitted coronavirus disease 2019 (COVID-19) patients.
CLINICAL CHARACTERISTICS
2/22/21
Patel RH, Acharya A, Chand HS, et al. | AIDS Res Hum Retroviruses
Aim: To examine trends of clinical outcomes among patients co-infected with HIV and SARS-CoV-2.
CLINICAL CHARACTERISTICS
2/22/21
Rambo APS, Goncalves LF, Fonzales AI, et al. | Sao Paulo Med J
Aim: To present scientific evidence regarding the impact of COVID-19 spreaders.
INFECTION CONTROL
2/22/21
Puyat JH, Ahmad H, Kazanjian H | CMH Initiative
Aim: To investigate home-based activities that have protective and therapeutic effects against mental health symptoms during pandemics and to identify if there are activities that are effective for specific groups.
2/22/21
Hawkins RB, Mehaffey JH, Charles EJ, et al. | Transplantation
Aim: To review the evidence on lung transplantation for severe post-coronavirus disease 2019 respiratory failure, including patient selection, perioperative management, and expected outcomes.
CANDIDATE THERAPEUTICS
2/22/21
Hoste L, Van Paemel R, Haerynck F | Eur J Pediatr
Aim: To perform a systematic review of published cases of this novel multisystem inflammatory syndrome in children associated with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/22/21
Silva DFO, Cobucci RN, de Paula Soares-Rachetti V, et al. | Cien Saude Colet
Aim: To identify the prevalence of anxiety among health professionals during the COVID-19 pandemic.
MENTAL HEALTH
2/22/21
Aloqbi HA, Shannaq GY, Douf TA, et al. | Ann Med Health Sci Res
Aim: To determine the prevalence of clinical and radiological manifestations among children and adolescents COVID-19 patients.
CLINICAL CHARACTERISTICS
2/22/21
Karimian M, Mansouri F, Borji M, et al. | Arch Clin Infect Dis
Aim: To systematically review studies on the prevention, diagnosis, and treatment of coronavirus in infants and children.
CANDIDATE THERAPEUTICS
2/22/21
Ahmed S, Jafri L, Hoodbhoy Z, et al. | Indian J Crit Care Med
Aim: To review the published literature on the prognostic role of serum procalcitonin (PCT) in COVID-19 cases.
CLINICAL CHARACTERISTICS
2/22/21
De Sire, A, Andrenelli E, Negrini F, et al. | Eur J Phys Rehabil Med
Aim: To report data of a systematic search performed on papers published in July 2020.
UPDATED
CLINICAL CHARACTERISTICS
2/22/21
Gesesew HA, Koye DN, Fetene DM, et al. | BMJ Open
Aim: To provide a comprehensive evidence on risk factors for transmission, disease severity and COVID-19 related deaths in Africa.
CLINICAL CHARACTERISTICS
2/22/21
Roshanshad A, Kamalipour A, Ashraf MA, et al. | Iran J Microbiol
Aim: To investigate the latest clinical evidence on the efficacy and safety of treatment with Remdesivir in hospitalized patients with COVID-19.
CANDIDATE THERAPEUTICS
2/22/21
Rahimzadeh M, Naderi N | J Med Virol
Aim: To shed light on COVID-19 mediated immune malfunction and highlight possible clues for effective treatments of this disease.
CANDIDATE THERAPEUTICS
2/20/21
Zhang JJY, Lee KS, Ong CW, et al. | Influenza Other Respir Viruses
Aim: To evaluate the diagnostic performance of serological testing in COVID?19 by providing summary sensitivity and specificity estimates with time from symptom onset.
DIAGNOSTICS
2/20/21
Sagredo-Olivares K, Morales-Gomez C, Aitken-Saavedra J | Med Oral Patol Oral Cir Bucal
Aim: To evaluate saliva as a diagnostic technique for COVID-19.
UPDATED
DIAGNOSTICS
2/20/21
Permana H, Huang I, Purwiga A, et al. | Pharmacol Rep
Aim: To address the association between the use of statins and risk of mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/19/21
Zhong Z, Li H, Zhu J, et al. | Medicine
Aim: To summarize the clinical characteristics of patients with severe or critically ill coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/19/21
Irfan O, Muttalib F, Tang K, et al. | Arch Dis Child
Aim: To compare paediatric COVID-19 disease characteristics, management and outcomes according to World Bank country income level and disease severity.
UPDATED
CLINICAL CHARACTERISTICS
2/19/21
Taherifard E, Taherifard E, Movahed H, et al. | Hematology
Aim: To systematically review the hematologic autoimmune complications in these patients.
CLINICAL CHARACTERISTICS
2/19/21
Javed A | CNS Neurol Disord Drug Targets
Aim: To assess the associated neurological manifestations with SARS CoV-2 infection.
CLINICAL CHARACTERISTICS
2/19/21
Creta M, Sagnelli C, Celentano G, et al. | J Med Virol
Aim: To highlight currently available literature data on the involvement of the urinary and male genital systems in SARS-SoV-2 infection.
CLINICAL CHARACTERISTICS
2/19/21
Dotto L, de Azevedo Kinalski M, Machado PS, et al. | J Evid Based Med
Aim: To assess the characteristics of different designs of systematic reviews (SRs) registered in the International Prospective Register of Systematic Reviews (PROSPERO) about COVID-19.
2/19/21
Godini H, Hoseinzadeh E, Hossini H | Rev Environ Health
Aim: To review the evidence on water and wastewater as potential sources of SARS-CoV-2 transmission.
INFECTION CONTROL
2/18/21
Maleki M, Anvari E, Hopke PK, et al. | Environ Res
Aim: To assess the association of air pollution especially particulate matter pollution in the transmission and acceleration of the spread of SARS-CoV-2.
INFECTION CONTROL
2/18/21
Shi L, Xu J, Xiao W, et al. | Ann Allergy Asthma Immunol
Aim: To explore the prevalence of asthma in COVID-19 patients and the relationship between asthma and COVID-19 patients with poor outcomes would be of paramount importance.
CLINICAL CHARACTERISTICS
2/18/21
Xu C, Yi Z, Cai R, et al. | Autoimmun Rev
Aim: To summarize the published and preprint literature that described the clinical characteristics and outcomes of COVID-19 patients with rheumatic diseases, and to provide a higher level of evidence for better clinical decision making.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Henrina J, Putra ICS, Lawrensia S, et al. | Proj Pediatr Cardiol
Aim: To investigate cardiac manifestations, treatment characteristics, and outcomes of paediatric inflammatory multisystem syndrome (PIMS) temporally associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) (PIMS-TS).
CLINICAL CHARACTERISTICS
2/17/21
de Souza DB, Frondana FV, Silva FD | Res Biomed Engineering
Aim: To establish reference parameters of ventilatory therapy used in the various levels of severity of adult patients affected by COVID-19, to assist health professionals and hospital managers who will purchase this equipment.
CANDIDATE THERAPEUTICS
2/17/21
Roshdy A, Zaher S, Fayed H, et al. | Front Cardiovasc Med
Aim: To report the cardiac tissue autopsy findings in coronavirus disease 2019 (COVID-19) decedents.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Maslennikov R, Poluektova E, Ivashkin V, et al. | Infect Dis
Aim: To provide a detailed systematic review of diarrhoea in adults with COVID-19.
CLINICAL CHARACTERISTICS
2/17/21
Bonora BM, Avogaro A, Fadini GP | J Endocrinol Invest
Aim: To summarize the current state of the art on DPP4i treatment and COVID-19-related outcomes in patients with diabetes mellitus.
CANDIDATE THERAPEUTICS
2/17/21
Atmosudigdo I, Pranata R, Anthonius M, et al.  | J Clin Exp Hepatol
Aim: To evaluate whether dyslipidemia affects the mortality and severity of COVID-19, we also aimed to evaluate whether other comorbidities influence the association.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Rauschenberg C, Schick A, Hirjak D, et al. | J Med Internet Res
Aim: To investigate the theoretical and empirical base, user perspective, safety, effectiveness, and cost-effectiveness of digital interventions in public mental health provision (i.e. mental health promotion, prevention and treatment of mental disorders) that may help to reduce the consequences of the current COVID-19 pandemic.
MENTAL HEALTH
2/17/21
Manyati TK, Mutsau M | Health Technol
Aim: To explore the effectiveness of telehealth interventions for the diagnosis, contact tracing and care of the corona virus disease of 2019 in sub Saharan Africa.
INFECTION CONTROL
2/17/21
Sirois F, Owens J | Front Psychiatry
Aim: To examine the factors associated with psychological distress among HCW during an outbreak.
UPDATED
MENTAL HEALTH
2/17/21
Nakhlband A, Fakhari A, Azizi H | Naunyn Schmiedebergs Arch Pharmacol
Aim: To assess outcomes of IFN-beta treatment in COVID-19 patients.
CANDIDATE THERAPEUTICS
2/17/21
Desborough J, Dykgraaf SH, Phillips C, et al. | Fam Pract
Aim: To synthesize accounts of primary care lessons learnt from past epidemics and their relevance to COVID-19.
INFECTION CONTROL
2/17/21
Bansal V, Mahapure KS, Bhurwal A, et al. | Front Med
Aim: To provide a detailed overview of existing literature on Remdesivir in COVID-19 to evaluate the benefits and adverse events. 
CANDIDATE THERAPEUTICS
2/17/21
Gao Y, Chen Y, Liu M, et al. | Epidemiol Infect
Aim: To clarify the association between nervous system diseases and severity or mortality in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Mohamed MFH, A-Shokri S, Yousaf Z, et al. | Front Cardiovasc Med
Aim: To systematically review the literature and explore the pooled prevalence of VTE, PE, and DVT in critically ill COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Winograd DM, Fresquez CL, Egli M, et al. | Patient Educ Couns
Aim: To review the evidence on the risk communication interventions to mitigate risk from viruses to determine if such interventions are efficacious.
INFECTION CONTROL
2/17/21
Kumar D, Severn M | CADTH
2/17/21
Kheyami ZA, Alharthi SS, Alanazi NS, et al. | Ann Med Health Sci Res
Aim: To determine the safety of systemic steroids and mortality rate in severe COVID-19 patients.
CANDIDATE THERAPEUTICS
2/17/21
Chaudhary R, Garg J, Houghton DE, et al. | Mayo Clin Proc Innov Qual Outcomes
Aim: To evaluate differences in thrombo-inflammatory biomarkers between patients with severe COVID-19 infection/death and mild infection.
CLINICAL CHARACTERISTICS
2/17/21
Jenner WJ, Kanji R, Mirsadraee S, et al. | J Thromb Thrombolysis
Aim: To identify the rate of thrombotic complications in ICU-treated patients with COVID-19, to inform recommendations for diagnosis and management.
CLINICAL CHARACTERISTICS
2/16/21
Umakanthan S, Chattu VK, Ranade AV, et al. | AIMS Public Health
Aim: To give a detailed insight into the recent trends of diagnosis and therapeutic options for COVID-19. 
CANDIDATE THERAPEUTICS
2/16/21
Labad J, Gonzalez-Rodriguez A, Cobo J, et al.  | PeerJ
Aim: To explore whether the coronavirus disease 2019 (COVID-19) pandemic is associated with toilet paper hoarding and to assess which risk factors are associated with the risk of toilet paper hoarding.
UPDATED
2/16/21
Sharifian-Dorche M, Sahraian MA, Fadda G, et al. | Mult Scler Relat Disord
Aim: To review the existing literature investigating the impact of disease-modifying therapies(DMT) on COVID-19 risks in this group of patients.
CANDIDATE THERAPEUTICS
2/16/21
Chang R, Elhusseiny KM, Yeh Y, et al. | PLoS One
Aim: To review the evidence on COVID-19 intensive care unit (ICU) patient characteristics, rates and risks of invasive mechanical ventilation (IMV) and associated outcomes.
UPDATED
CLINICAL CHARACTERISTICS
2/16/21
Sallam M | Vaccines
Aim: To assess the acceptance rates for COVID-19 vaccine(s) in different countries worldwide, which can provide an initial step to study the factors implicated in regional and cultural differences behind COVID-19 vaccine hesitancy.
INFECTION CONTROL
2/16/21
Ding H, He F, Lu YG, et al. | Eur Rev Med Pharmacol Sci
Aim: To evaluate the effects of non-drug interventions on anxiety, depression and sleep in patients with COVID-19 to provide guidance for clinical application.
MENTAL HEALTH
2/16/21
Wang J, Zhong Z, Mo Y, et al. | Eur Rev Med Pharmacol Sci
Aim: To determine the incidence of the clinical manifestations of COVID-19 in children.
UPDATED
CLINICAL CHARACTERISTICS
2/16/21
Fiest KM, Leigh JP, Krewulak KD, et al. | BMC Psychiatry
Aim: To review the evidence on the experiences and management of psychological symptoms in physicians during infectious disease outbreaks to better understand and support physician health during this unprecedented time.
MENTAL HEALTH
2/16/21
Ebina-Shibuya R, Namoong H, Horita N, et al. | J Thorac Dis
Aim: To evaluate HCQ/CQ treatment for COVID-19.
CANDIDATE THERAPEUTICS
2/16/21
Cavalcante-Leao BL, de Araujo C, Basso I, et al. | J Clin Exp Dent
Aim: To verify whether there is evidence in the literature regarding the decrease in viral load present in saliva after using three types of mouthwashes.
UPDATED
INFECTION CONTROL
2/16/21
Sarria-Guzman Y, Fusaro C, Bernal JE, et al. | J Infect Dev Ctries
Aim: To identify and to evaluate the reports associated on Knowledge, Attitude and Practices (KAP) towards COVID-19 pandemic in America.
2/16/21
Zhu F, Zozaya C, Zhou Q, et al. | Arch Dis Child Fetal Neonatal Ed
Aim: To systematically review and meta-analyse the available evidence for the presence of SARS-CoV-2 genome in the breastmilk of mothers who tested positive for COVID-19.
INFECTION CONTROL
2/16/21
Zinellu A, Mangoini AA | Front Med
Aim: To review the available evidence on the clinical implications of this protein specifically in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/16/21
Khan FA, Stewart I, Fabbri L, et al. | Thorax
Aim: To systematically review and assess the effectiveness of specific interleukin-1 and -6 inhibitors for the treatment of coronavirus-related infections. 
UPDATED
CANDIDATE THERAPEUTICS
2/16/21
Darbandi A, Asadi A, Ghanavati R, et al. | Int J Infect Dis
Aim: To evaluate the effects of probiotic on patient’s respiratory tract infection (RTI), a systematic review was conducted on randomized controlled trials (RCTs). 
CANDIDATE THERAPEUTICS
2/16/21
Bignardi PR, Vengrus CS, Aquino BM, et al. | Pathog Glob Health
Aim: To assess the association of hydroxychloroquine use with the virological cure, clinical recovery, mortality, and development of adverse effects in patients with COVID-19. 
CANDIDATE THERAPEUTICS
2/16/21
Sarfraz A, Sarfraz Z, Razzack AA, et al. | Clin Appl Thromb Hermost
Aim: To determine the risk of developing VTE after corticosteroid administration during COVID-19 treatment.
CANDIDATE THERAPEUTICS
2/15/21
Udeh R, Advani S, de Guadiana Romualdo LG, et al. | J Clin Med
Aim: To carefully evaluate the levels of calprotectin (serum, plasma or fecal) in severe and non-severe COVID-19, and also identify the implications of raised levels of calprotectin.
DIAGNOSTICS
2/15/21
Yazew BG, Abate HK, Mekonnen CK | Patient Prefer Adherence
Aim: To investigate the status of people’s knowledge, attitude, and practice about coronavirus disease preventive measures in Ethiopia in 2020.
INFECTION CONTROL
2/13/21
Chowdhury P, Paul SK, Kaisar S, et al. | Transp Rep E Logist Transp Rev
Aim: To  systematically review existing research on the COVID-19 pandemic in supply chain disciplines.
2/13/21
Zace D, Hoxhaj I, Orfino A, et al.  | J Psychiatr Res
Aim: To identify and summarize the implemented interventions to deal with mental health issues of HCWs during infectious disease outbreaks, and report their effectiveness.
UPDATED
MENTAL HEALTH
2/12/21
Singh B, Ryan H, Kredo T, et al. | Cochrane Database Syst Rev
Aim: To evaluate the effects of chloroquine or hydroxychloroquine for treatment people with COVID-19 and for preventing infection in people at risk of exposure or exposed to SARS-CoV-2.
UPDATED
CANDIDATE THERAPEUTICS
2/12/21
Ng WH, Tipih T, Makoah NA, et al. | mBio
Aim: To evaluate the correlation between comorbidities and their role in the exacerbation of disease in COVID-19 patients leading to fatal outcomes. 
CLINICAL CHARACTERISTICS
2/12/21
Nanda A, Hung I, Kwong A, et al. | J Evid Based Med
Aim: To evaluate the preclinical and clinical evidence on use of cloth and surgical face masks in SARS-CoV-2 transmission and proposes a trial to gather further evidence.
INFECTION CONTROL
2/11/21
Nasiri K, Dimitrova A | J Dent Sci
Aim: To evaluate saliva specimen in comparison to nasopharyngeal swab (NPS) specimen.
DIAGNOSTICS
2/11/21
Tur-Kaspa I, Tur-Kaspa T, Hildebrand G, et al. | F S Rev
Aim: To determine if COVID-19 is an STD or not, and to clarify its possible effect on fertility.
CLINICAL CHARACTERISTICS
2/11/21
Yan W, Chen D, Bigambo FM, et al. | BMC Infect Dis
Aim: To determine differences in blood cells, lymphocyte subsets, and cytokines in COVID-19 patients with different clinical stages.
CLINICAL CHARACTERISTICS
2/11/21
Vergara-Merino L, Meza N, Couve-Perez C, et al. | Acta Obstet Gynecol Scand
Aim: To conduct a comprehensive analysis of the current evidence on prognosis of COVID-19 in pregnant women.
CLINICAL CHARACTERISTICS
2/11/21
Bauer M, Groesdonk HV, Preissing F, et al. | Anaesthesist
Aim: To estimate 30-day and 90-day mortality of patients with sepsis and patients with septic shock in Germany and to compare the mortality with that of other industrialized regions (Europe, North America).
2/11/21
Jin Y, Trope GE, El-Defrawy S, et al. | Eur J Ophthalmol
Aim: To summarize COVID-19 research endeavors by ophthalmologists/researchers in terms of publication numbers, journals and author countries, and to detail key findings.
CLINICAL CHARACTERISTICS
2/11/21
Bavishi C, Whelton PK, Mancia G, et al. | J Hypertens
Aim: To evaluate the association of angiotensin-converting-enzyme inhibitors (ACEI) or AT1 blockers (ARB) therapy with clinical outcomes in patients with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/11/21
Thompson H, Mousa A, Dighe A, et al.  | Clin Infect Dis
Aim: To estimate secondary attack rates (SAR) and observed reproduction numbers (Robs) in different settings exploring differences by age, symptom status, and duration of exposure.
UPDATED
INFECTION CONTROL
2/11/21
Alonso SG, Marques G, Barrachina I, et al. | Health Technol
Aim: To present a systematic review of the application of telemedicine and e-health systems to combat COVID-19. 
INFECTION CONTROL
2/10/21
Hariyanto TI, Rizki NA, Kurniawan A | Int Arch Otorhinolaryngol
Aim: To analyze the potential usefulness of anosmia or hyposmia in the detection of the COVID-19 infection.
DIAGNOSTICS
2/10/21
Syangtan G, Bista S, Dawadi P, et al. | Front Public Health
Aim: To review the evidence on the frequency of asymptomatic individuals and estimated occurrence by age group and gender.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Jayant K, Reccia I, Virdis F, et al. | Clin Transplant
Aim: To determine the pooled prevalence of outcomes among hospitalized LTx recipients with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Dhar SK, Vishnupriayn K, Damodar S, et al. | Heliyon
Aim: To establish association between induced cytokines and COVID-19 disease severity to help in prognosis and clinical care.
CLINICAL CHARACTERISTICS
2/10/21
 | NSW Health COVID-19 Critical Intelligence Unit
2/10/21
Marafini I, Troncone E, Rocchetti I, et al. | Front Pharmacol
Aim: To determine the risk of RTIs with vedolizumab in patients with IBD.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Kumar J, Meena J, Yadav A, et al.  | J Matern Fetal Neonatal Med
Aim: To synthesize the current evidence for the presence of SARS-CoV-2 RNA in the human milk of mothers with confirmed COVID-19 and its potential role in neonatal SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Umnuaypornlert A, Kanchanasurakit S, Lucero-Prisno DE, et al. | Tob Induc Dis
Aim: To determine the association between smoking and disease severity in COVID-19 infected patients.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Dorantes-Acosta E, Ávila-Montiel D, Klünder-Klünder M, et al. | Front Oncol
Aim: To understand the survival and associated complications in pediatric cancer patients as well as their hospitalization, intensive care, and ventilation care (supplemental oxygen/endotracheal intubation) needs.
CLINICAL CHARACTERISTICS
2/10/21
Nassar M, Nso N, Baraka B, et al. | Diabetes Metab Syndr
Aim: To summarize the prevalence, clinical findings, and outcomes of COVID-19 in patients with T1DM, based on the findings of available evidence.
CLINICAL CHARACTERISTICS
2/9/21
Chedid M, Waked R, Haddad E, et al. | J Infect Public Health
Aim: To report available information in the literature regarding frequency, indications, types of antibiotic usage, duration, and their efficacy in Covid-19 patients.
CANDIDATE THERAPEUTICS
2/8/21
Sunjaya AP, Allida SM, Di Tanna GL, et al. | J Asthma
Aim: To summarise evidence on the risk of infection, severe illness and death from COVID-19 in people with asthma.
CLINICAL CHARACTERISTICS
2/8/21
Laurentius A, Mendel B, Prakoso R | Egypt Heart J
Aim: To show clinical outcome of renin-angiotensin-aldosterone system blockers in hospital treatment of hypertensive patients with coronavirus disease 2019
CLINICAL CHARACTERISTICS
2/8/21
Bhatta M, Nandi S, Dutta S, et al. | Hum Vaccin Immunother
Aim: To analyze the availability, development and status of new COVID-19 vaccine candidates as well as the status of vaccines for other diseases that might be effective against SARS-CoV-2 infection.
CANDIDATE THERAPEUTICS
2/8/21
Li P, Li L, Wang S, et al. | Cancer Med
Aim: To systematically review the present evidence on the relationship between antitumor therapy and the clinical outcomes of COVID?19 and to analyze and summarize the available studies in this meta?analysis.
CLINICAL CHARACTERISTICS
2/8/21
Vegivinti CTR, Pederson JM, Saravu K, et al. | J Clin Apher
Aim: To examine clinical outcomes associated with convalescent plasma therapy in COVID-19 patients.
CANDIDATE THERAPEUTICS
2/8/21
Dabone C, Mbagwu I, Muray M, et al. | J Racial Ethn Health Disparities
Aim: To assess the food insecurity conditions of ACB populations globally during the COVID-19 pandemic.
2/8/21
Servante J, Swallow G, Thornton JG, et al. | BMC Pregnancy Childbirth
Aim: To determine the rate of arterial or venous thrombosis in pregnant women with confirmed or suspected COVID-19 and to estimate the rate of acquired coagulopathy in pregnant women with confirmed or suspected COVID-19.
CLINICAL CHARACTERISTICS
2/8/21
Mir T, Sattar Y, Ahmad J, et al. | Catheter Cardiovasc Interv
Aim: To meta?analyze studies that examined in?hospital cardiac arrest in COVID patients.
CLINICAL CHARACTERISTICS
2/8/21
Kim DH, Kim SW, Stybayeva G, et al. | Clin Exp Otorhinolaryngol
Aim: To evaluate the diagnostic value of the various symptoms of COVID-19 in the screening of this disease.
DIAGNOSTICS
2/8/21
Yuan K, Gong Y, Liu L, et al. | Mol Psychiatry
Aim: To provide a reliable estimate of the worldwide prevalence of PTSD after large-scale pandemics as well as associated risk factors.
MENTAL HEALTH
2/8/21
 | NSW Health COVID-19 Critical Intelligence Unit
2/8/21
Pal R, Banerjee M, Yadav U, et al. | Postgrad Med J
Aim: To provide an updated summary and collate the effect of statin use on clinical outcomes in COVID-19 using unadjusted and adjusted risk estimates.
CANDIDATE THERAPEUTICS
2/5/21
Pasin L, Cavalli G, Navalesi P, et al. | Eur J Intern Med
Aim: To investigate the effect of anakinra in COVID-19 on survival and need for mechanical ventilation.
CANDIDATE THERAPEUTICS
2/5/21
Beyrouti R, Best JG, Chandratheva A, et al. | J Neurol
Aim: To describe the characteristics of spontaneous symptomatic intracerebral haemorrhage (ICH) associated with COVID-19.
CLINICAL CHARACTERISTICS
2/5/21
Xu Z, Tang Y, Huang Q, et al. | BMC Nephrol
Aim: To evaluate the incidence of AKI in hospitalized COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/4/21
Belsky JA, Tullius BP, Lamb MG, et al. | J Infect
Aim: To define clinical features, laboratory testing, therapeutic interventions and outcomes in immunocompromised patients and then compared these results to the general population with COVID-19.
CLINICAL CHARACTERISTICS
2/4/21
Anderson G, Casasanta D, Cocchieri A, et al. | J Clin Nurs
Aim: To identify the main diagnostic features of SARS-CoV-2 positive patients at the time of hospitalization and their prevalence.
DIAGNOSTICS
2/4/21
Aghalari Z, Dahms H, Sosa-Hernandez JE, et al. | Environ Res
Aim: To evaluate SARS-COV-2 transmission through indoor air in hospitals and its prevention methods.
INFECTION CONTROL
2/4/21
Jain V, Kanchan T, Krishan K | Acta Biomed
Aim: To review the evidence on the vertical transmission of SARS-CoV-2.
INFECTION CONTROL
2/4/21
Elshazli RM, Kline A, Elgaml A, et al. | J Med Virol
Aim: To identify COVID-19 patients presenting with gastrointestinal (GI) symptoms during the first and second pandemic waves and investigate their association with the disease outcomes.
CLINICAL CHARACTERISTICS
2/4/21
Li G, Yang Y, Gao D, et al. | Int J Med Sci
Aim: To comprehensively explore the prevalence of transaminase elevation and liver injury in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/4/21
Alamer AA, Almulhim AS, Alrashed AA, et al. | Healthcare
Aim: To estimate the pooled risks of mortality and disease severity associated with ACEI/ARB use during the first wave of the pandemic.
CLINICAL CHARACTERISTICS
2/4/21
Rezagholizadeh A, Khiali S, Sarbakhsh P, et al. | Eur J Pharmcol
Aim: To evaluate the efficacy and safety of remdesivir administration in COVID-19 patients. 
CANDIDATE THERAPEUTICS
2/3/21
 | CMH Initiative
2/3/21
Naeini MB, Sahebi M, Nikbakht F, et al. | Obes Med
Aim: To quantify meta-analytic findings on the association of cardiovascular disease (CVD) comorbidities and COVID-19 severity.
CLINICAL CHARACTERISTICS
2/3/21
Hatmi ZN | SN Compr Clin Med
Aim: To conduct a systematic review of published systematic reviews to provide comprehensive updated information on COVID-19.
CLINICAL CHARACTERISTICS
2/3/21
He X, Cheng X, Feng X, et al. | Front Public Health
Aim: To review the clinical symptoms of the COVID-19 epidemic systematically.
CLINICAL CHARACTERISTICS
2/3/21
Hasnain M, Pasha MF, Ghani I | J Biosaf Biosecur
Aim: To review the evidence on the combined measures taken to control the transmission of COVID-19 in Wuhan.
INFECTION CONTROL
2/3/21
Li J, Liao X, Zhou Y, et al. | Shock
Aim: To review the evidence on the response to glucocorticioids treatment in COVID-19 and SARS patients.
UPDATED
CANDIDATE THERAPEUTICS
2/3/21
Castaneda CA, Castillo M, Rojas JL, et al. | Rev Peru Med Exp Salud Publica
Aim: To describe the risk of infection and developing severe COVID-19 in cancer patients.
UPDATED
CLINICAL CHARACTERISTICS
2/3/21
Lopez-Valenciano A, Suarez-Iglesias D, Sanchez-Lastra MA, et al. | Front Psychol
Aim: To analyze the impact that the COVID-19 lockdown had on the amount of physical activity performed by university students.
2/3/21
Scooppettuolo P, Borrelli S, Naeije G | Brain Behav Immun Health
Aim: To provide a clinical approach of SARS-CoV-2 neurological complications based on the direct or indirect (systemic/immune-mediated) role of the SARS-CoV-2 in their genesis.
CLINICAL CHARACTERISTICS
2/3/21
Nasiri N, Sharifi H, Bazrafshan A, et al. | J Ophthalmic Vis Res
Aim: To investigate the prevalence of ocular manifestations in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/3/21
Pourmalek F, Hemami MR, Janani L, et al. | BMC Public Health
Aim: To inform the researchers about the methodology and results of epidemic estimation studies performed for COVID-19 epidemic in Iran, we aimed to perform a rapid review.
UPDATED
2/3/21
Cevik M, Tate M, Lloyd O, et al. | Lancet Microbe
Aim: To characterise the viral load dynamics of SARS-CoV-2, duration of viral RNA shedding by RT-PCR, and viable virus shedding in various body fluids, and to compare SARS-CoV-2 viral dynamics with those of SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV).
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Xiang G, Li X, Chen Z, et al. | Ann Palliat Med
Aim: To systematically review the clinical risk factors for fatal outcome of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Li H, Zhao Y, Zhou L, et al. | Dermatol Ther
Aim: To present heterogeneous cutaneous, histopathological manifestations in COVID?19 patients, to investigate the possible relationship between cutaneous manifestations and histopathological features in COVID?19 infection.
CLINICAL CHARACTERISTICS
2/1/21
Pijls BG, Jolani S, Atherley A, et al. | BMJ Open
Aim: To describe the associations of age and sex with the risk of COVID-19 in different severity stages ranging from infection to death.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
AlJohani AMA, Tharwat TJA, Mahrous KW, et al. | World Fam Med J
Aim: To outline and identify a wide range of diagnostic and therapeutic options for COVID-19.
CANDIDATE THERAPEUTICS
2/1/21
Ghimire S, Sharma S, Patel A, et al. | SN Compr Clin Med
Aim: To provide a more comprehensive and generalizable understanding of the GI manifestations, and its association with severity in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/1/21
Yisak H, Ewunetei A, Kefale B, et al. | Risk Manag Healthc Policy
Aim: To summarize and decide if there were a link between vitamin D status and COVID-19 infection and prognosis.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Sood M, Sharma S, Sood I, et al. | SN Compr Clin Med
Aim: To analyse the clinical features, proposed pathogenesis and current treatment options for effective management of children with this novel entity.
CLINICAL CHARACTERISTICS
2/1/21
Diaz LA, Idalsoaga F, Cannistra M, et al. | World J Gastroenterol
Aim: To characterize hepatic pathological findings in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Wibowo A, Pranata R, Astuti A, et al. | J Intensive Care
Aim: To assess whether ventricular longitudinal strain can be used as a prognostication tool in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Lee RA, Herigon JC, Benedetti A, et al. | J Clin Microbiol
Aim: To understand the performance of alternative sample types compared to NP swabs
UPDATED
DIAGNOSTICS
2/1/21
Yoon SH, Yang S, Cho H, et al.  | Eur Rev Med Pharmacol Sci
Aim: To evaluate the diagnostic accuracy of the Food and Drug Administration Emergency Use Authorization (FDA-EUA) authorized point-of-care tests (POCTs) for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
UPDATED
DIAGNOSTICS
2/1/21
d'Ettore G, Ceccarelli G, Santinelli L, et al. | Int J Environ Res Public Health
Aim: To analyze the literature to discover which topics have been focused on and what the latest developments are in managing the occupational risk of PTSS in HCWs during the current pandemic.
MENTAL HEALTH
2/1/21
Santabarbara J, Bueno-Notivol J, Lipinicki DM, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To review the evidence on the prevalence of anxiety in health care professionals during the COVID-19 pandemic.
MENTAL HEALTH
2/1/21
Yang J, Zheng Y, Gou X, et al. | Int J Infect Dis
Aim: To assess the prevalence of comorbidities in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients and the risk of underlying diseases in severe patients compared to non-severe patients.
CLINICAL CHARACTERISTICS
2/1/21
Merola E, Armelao F, de Pretis G | Acta Gastroenterol Belg
Aim: To assess the frequency of gastrointestinal (GI) involvement in COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Martha JW, Wibowo A, Pranata R | Postgrad Med J
Aim: To evaluate the prognostic performance of elevated lactate dehydrogenase (LDH) in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Gronholm P, Nose M, van Brakel WH, et al. | Epidemiol Psychiatr Sci
Aim: To develop recommendations for strategies and interventions to reduce stigma and discrimination related to COVID-19.
UPDATED
MENTAL HEALTH
2/1/21
Agostini F, Mangone M, Ruiu P, et al. | J Rehabil Med
Aim: To identify the best evidence to define rehabilitative approaches to acute and post-acute phases of coronavirus 2019 (COVID-19) disease.
CANDIDATE THERAPEUTICS
2/1/21
Al-abdouh A, Bizanti A, Barbarawi M, et al. | Contemp Clin Trials
Aim: To evaluate the effect of remdesivir in the treatment of moderate and severe COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
2/1/21
Lee HW, Yoon C, Jang EJ, et al. | Thorax
Aim: To investigate if ACEI/ARB use is associated with the risk of mortality and severe disease in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Zhang T, Huang W, Guan W, et al. | J Thorac Dis
Aim: To review the evidence on the clinical characteristics between severe and non-severe pateints in the outbreak of COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Uaprasert N, Moonla C, Sosothikul D, et al. | Clin Appl Thromb Hermost
Aim: To estimate the burden of systemic coagulation activation in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Chen C, Zhu C, Yan D, et al. | Int J Infect Dis
Aim: To summarize the epidemiological and radiographical characteristics of asymptomatic infections with COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Prati G, Mancini AD | Psychol Med
Aim: To determine the psychological impact of COVID-19 lockdowns on the general population.
MENTAL HEALTH
2/1/21
Bastos ML, Perlman-Arrow S, Menzies D, et al. | Ann Intern Med
Aim: To determine the difference in sensitivity for SARS-CoV-2 detection between nasopharyngeal swabs and saliva and estimate the incremental cost per additional SARS-CoV-2 infection detected with nasopharyngeal swabs.
UPDATED
DIAGNOSTICS
2/1/21
Han YJ, Lee KW, Yoon S, et al. | Theranostics
Aim: To highlight therapeutic agents that might be effective in treating COVID-19.
CANDIDATE THERAPEUTICS
1/30/21
Robaina-Castellanos GR, de la Caridad Riesgo-Rodriguez S | MEDICC Rev
Aim: To summarize and analyze the published evidence on forms of SARS-CoV-2 vertical transmission (either intrauterine or intrapartum).
INFECTION CONTROL
1/29/21
Khatami F, Saatchi M, Zadeh SST, et al. | Sci Rep
Aim: To determine the diagnostic value of an initial chest CT scan in patients with COVID-19 infection in comparison with RT-PCR. 
DIAGNOSTICS
1/29/21
Yu YJ, Park YS, Keller A, et al. | Int J Environ Res Public Health
Aim: To synthesize existing findings (both qualitative and quantitative) that focus on the social and cultural impacts of coronaviruses in order to gain a better understanding of the COVID-19 pandemic.
1/29/21
Lawes-Wickwar S, Ghio D, Tang MY, et al. | Vaccines
Aim: To identify and synthesise evidence relating to effective messaging for encouraging vaccination in order to prevent virus transmission during pandemics or epidemics.
UPDATED
INFECTION CONTROL
1/29/21
Peravali M, Joshi I, Ahn J, et al. | JTO Clin Res Rep
Aim: To outline patient characteristics, challenges in diagnosis and treatment, and outcomes of lung cancer patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Goel H, Gupta I, Mourya M, et al. | Obstet Gynecol Sci
Aim: To review the evidence on the clinical and laboratory parameters of COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Kinobe RT, Owens L | Fundam Clin Pharmacol
Aim: To present an integrative, critical appraisal of the qualitative and quantitative antiviral properties of ivermectin for putative applications in agriculture and medicine with examination of SARS?CoV?2.
CANDIDATE THERAPEUTICS
1/29/21
Tleyjeh IM, Bin Abdulhak AA, Tlayjeh H, et al. | Am J Ther
Aim: To perform a meta-analysis of the association between prior use of ACEIs and ARBs and the risk of SARS-CoV-2 infection or hospitalization due to COVID-19 disease.
CLINICAL CHARACTERISTICS
1/29/21
Langford BJ, So M, Raybardhan S, et al. | Clin Microbiol Infect
Aim: To estimate the prevalence and associated factors of antibiotic prescribing in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Arias FA, Chavez PT, Panato AM, et al. | J of Pharmaceutical Res
Aim: To conduct a systematic review of the possible antivirals studied that could be useful in this public health catastrophe.
CANDIDATE THERAPEUTICS
1/29/21
Lee JJ, Montazerin SM, Jamil A, et al. | J Med Virol
Aim: To review and synthesize the current evidence on the association of RDW levels with COVID?19 mortality and severity.
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Mendes NF, Jara CP, Mansour E, et al. | Allergy Asthma Clin Immunol
Aim: To conduct a systematic review of the diagnosis of asthma as a premorbid condition in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Silverio A, Di Maio M, Citro R, et al. | BMC Cardiovasc Disord
Aim: To investigate the relationship between cardiovascular risk factors and in-hospital mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Baldini T, Asioli GM, Romoli M, et al. | Eur J Neurol
Aim: To systematically review the available evidence in the literature for cerebral venous thrombosis (CVT) in association with coronavirus disease-2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Chen M, Qin R, Mei J, et al. | Int J Infect Dis
Aim: To investigate the diagnostic effectiveness of SARS-CoV-2 specific antibodies stratified by different positive results.
DIAGNOSTICS
1/29/21
Jafari M, Pormohammad A, Sheikh Neshin SA, et al. | Rev Med Virol
Aim: To provide comprehensive data regarding pregnant patients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
1/29/21
Huang C, Soleimani J, Herasevich S, et al. | Mayo Clin Proc
Aim: To synthesize the current and emerging literature describing the clinical features, treatment, outcomes, and risk factors associated with poor prognosis among critically ill patients with COVID-19 during the early months of the pandemic. To provide frontline clinicians with insights for the effective management of severely ill patients with COVID-19. To identify knowledge gaps to guide future research endeavors.
CLINICAL CHARACTERISTICS
1/29/21
Singh AK, Jena A, Kumar-M P, et al. | Intest Res
Aim: To review the evidence on the various clinical manifestations of SARS-CoV-2 in patients with IBD, and to estimate the pooled prevalence of different clinical manifestations.
CLINICAL CHARACTERISTICS
1/29/21
Barycka K, Szarpak L, Filipiak KJ, et al. | PLoS One
Aim: To review the relevant and available published RCTs with the aid of the increased power of meta-analytic methods in order to assess the effectiveness of medical masks and N95 respirators in reducing the risk of respiratory infections.
INFECTION CONTROL
1/29/21