COVID-19 Evidence Reviews
as of 12/1/20
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12/01/2020
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Completed Reviews
 
= living review
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
latest update
date
report
select
11/30/20
Graber K, Byrne E, Goodacre E, et al. | Child Care Health Dev
Aim: To review of the impact of quarantine, isolation, or other restrictive environments on children’s play and whether play may mitigate the adverse effects of such restrictions.
RECENTLY UPDATED
11/30/20
da Rosa Mesquita R, Silva LCF, Santana FMS, et al. | Wien Klin Wochenschr
Aim: To systematize the literature regarding clinical manifestations of patients with confirmed COVID-19.
11/30/20
Wang Z, Deng H, Ou C, et al. | Medicine
Aim: To compare the differences in the field of demographic, comorbidities, clinical symptoms, complications and outcomes between severe and non-severe COVID-19.
11/30/20
Raja MA, Mendoza MA, Villavicencio A, et al. | Transplant Rev
Aim: To help expand our current limited knowledge base regarding COVID-19 in SOT recipients, especially looking at clinical presentations, treatment modalities and outcomes.
11/30/20
Meher BR, Padhy BM, Das S, et al. | J Assoc Physicians India
Aim: To evaluate the currently available data to provide evidence about CPT in COVD-19 patients. 
11/30/20
Amiri-Dashatan N, Koushki M, Ghorbani F, et al. | Gastroenterol Hepatol Bed Bench
Aim: To determine whether patients with elevated CRP, TNF?, and IL-6 levels may be at increased risk for severe infection and liver damage of COVID-19.
11/30/20
Makvandi S, Ashtari S, Vahedian-Azimi A | Gastroenterol Hepatol Bed Bench
Aim: To evaluate the symptoms of COVID-19 in pregnant women with a focus on gastrointestinal symptoms.
11/30/20
Bell V, Wade D | Soc Psychiatr Epidemiol
Aim: To estimate the additional burden of working directly with infected patients during epidemic and pandemic health emergencies.
RECENTLY UPDATED
11/30/20
Hannum ME, Ramirez VA, Lipson SJ, et al. | Chem Senses
Aim: To provide a comprehensive assessment of methodologies currently employed to quantify smell loss in COVID-19–positive patients and examine whether method type affects reported prevalence of smell loss in COVID-19 patients.
RECENTLY UPDATED
11/30/20
Mousquer GT, Peres A, Fiegenbaum M | Tuberculosis
Aim: To conduct a systematic review on the current literature on TB/COVID-19 co-infection cohorts, evaluating clinical and epidemiological data, focusing on its implications to the immune system.
11/30/20
Bekele F, Sheleme T, Fekadu G, et al. | SAGE Open Med
Aim: To summarize the knowledge, attitudes, and practice of COVID-19 among the general population and health workers across the globe.
11/30/20
Afra HS, Amiri-Dashatan N, Ghorbani F, et al. | Gastroenterol Hepatol Bed Bench
Aim: To report a pooled analysis of the association of the circulating levels of liver enzymes and total bilirubin with severe and non-severe COVID-19.
11/30/20
Bareeqa SB, Ahmed SI, Samar SS, et al. | Int J Psychiatry Med
Aim: To quantify COVID-19 mental health issues and its prevalence in China during the early period of the COVID-19 crisis.
RECENTLY UPDATED
11/30/20
Thrinuavukkarasu S, Kapoor N, Tina Cao, et al. | Diabetes Obes Metab
Aim: To examine the proportion of newly diagnosed diabetes in COVID-19 patients.
11/30/20
Azam M, Sulistiana R, Ratnawati M, et al. | Sci Rep
Aim: To estimate the incidence of recurrent SARS-CoV-2 RNA positivity after recovery from COVID-19 and to determine the factors associated with recurrent positivity. 
RECENTLY UPDATED
11/30/20
Maraolo AE, Grosi A | Immun Inflamm Dis
Aim: To gauge the safety profile of HCQ/CQ in the context of COVID?19 pandemic on the basis of data from RCTs published so far, to highlight the trade?off between pros and cons of HCQ/CQ repurposing to treat or prevent SARS?CoV?2 infection.
11/30/20
Jammu A, Chasen M, Lofters A, et al. | Support Care Cancer
Aim: To synthesise the available knowledge regarding the impact of the COVID-19 pandemic.
RECENTLY UPDATED
11/30/20
Allan SM, Bealey R, Birch J, et al. | Eur J Psychotraumatol
Aim: To estimate the prevalence of common mental health disorders in HCWs based in hospitals where pandemic-affected patients were treated.
RECENTLY UPDATED
11/30/20
Islam N, Salameh JP, Leeflang MMG, et al. | Cochrane Database Syst Rev
Aim: To determine the diagnostic accuracy of chest imaging (computed tomography (CT), X?ray and ultrasound) in people with suspected or confirmed COVID?19.
RECENTLY UPDATED
DIAGNOSTICS
11/27/20
Arruda AG, Beyene TJ, Kieffer J, et al. | Animals
Aim: To summarize the available literature on swine depopulation methods and to highlight critical gaps in knowledge.
11/27/20
Wang Z, Deng H, Ou C, et al. | Medicine (Baltimore)
Aim: To compare the differences in the field of demographic, comorbidities, clinical symptoms, complications and outcomes between severe and non-severe COVID-19. To conclude the potential risk factors to severe COVID-19 patients.
RECENTLY UPDATED
11/27/20
Zhang X, Yang X, Jiao H, et al. | Aging
Aim: To investigate the role of coagulation dysfunction in the severity of COVID-19 progression.
CLINICAL CHARACTERISTICS
11/27/20
Asadi-Pooya AA, Simani L, Shahisavandi M, et al. | Neurol Sci
Aim: To discuss the evidence on the occurrence of de novo seizures in patients with COVID-19, the consequences of this catastrophic disease in people with epilepsy (PWE), and the electroencephalographic (EEG) findings in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/27/20
Griffin J, Casey M, Collins Á, et al. | BMJ Open
Aim: To conduct a review of available evidence to advise on appropriate parameter values for serial interval and generation time in national COVID-19 transmission models for Ireland and on methodological issues relating to those parameters.
RECENTLY UPDATED
11/27/20
Rostami A, Sepidarkish M, Leeflang MMG, et al. | Clin Microbiol Infect
Aim: To estimate the global and regional seroprevalence rates in humans of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and to assess whether seroprevalence is associated with geographical, climatic and/or sociodemographic factors.
CLINICAL CHARACTERISTICS
11/27/20
Kuek JTY, Ngiam LXL, Kamal NHA, et al. | Philos Ethics Humanit Med
Aim: To evaluate prevailing accounts of physicians facing dying patients in ICUs through the lens of Personhood.
MENTAL HEALTH
11/27/20
Amicucci M, Mastronuzzi A, Ciaralli I, et al. | J Clin Med
Aim: To collect and analyze scientific literature regarding the management, interventions, and strategies to prevent the spread of COVID-19 in children with cancer.
INFECTION CONTROL
11/27/20
Dar-Odeh N, Elsayed S, Babkair H, et al. | J Dent Sci
Aim: To highlight COVID-19 pharmacotherapeutic agents that are relevant to dental practice in terms of their clinical indications in COVID-19 and dental practice, as well as their adverse effects as they impact the dental patient.
CANDIDATE THERAPEUTICS
11/25/20
Vakhshoori M, Heidarpour M, Shafie D, et al. | Arch Iran Med
Aim: To analyze the available COVID-19 data on acute cardiac injury, using troponin and brain natriuretic peptide (BNP) levels.
CLINICAL CHARACTERISTICS
11/25/20
Yang X, Tian S, Guo H | Int Immunopharmacol
Aim: To gain clarity regarding AKI incidence and renal replacement therapy (RRT) use in COVID-19 patients.
CLINICAL CHARACTERISTICS
11/25/20
Karabay M, Ç?nar N, Karakaya Suzan Ö, et al. | J Matern Fetal Neonatal Med
Aim: To investigate the available evidence describing neonatal outcomes in newborns who have SARS-CoV-2 infection in order to guide prevention of COVID-19 in newborns.
RECENTLY UPDATED
INFECTION CONTROL
11/25/20
Chu C, Zeng S, Hasan AA, et al. | Br J Clin Pharmacol
Aim: To review the evidence on the effect of RAAS blockers on the expression of ACE2 and the risk of SARS-Cov-2 infection.
CLINICAL CHARACTERISTICS
11/25/20
Sameni F, Hajikhani B, Yaslianifard S, et al. | Front Med
Aim: To provide a systematic review and meta-analysis of various skin manifestations among patients with COVID-19 through case reports/case series and prevalence studies.
CLINICAL CHARACTERISTICS
11/25/20
Jindal R, Chauhan P | J Family Med Prim Care
Aim: To describe the cutaneous manifestations of COVID-19 patients from diverse regions with the aim of highlighting any important associations.
CLINICAL CHARACTERISTICS
11/25/20
Garg M, Gupta P, Maralakunte M, et al. | Clin Imaging
Aim: To evaluate pooled prevalence, sensitivity, and specificity of chest computed tomography (CT) and radiographic findings for novel coronavirus-2019 (COVID-19) pneumonia.
DIAGNOSTICS
11/25/20
Kiss S, Gede N, Hegyi P, et al. | Med Microbiol Immunol
Aim: To review the evidence on the correlation between early changes in the laboratory parameters and the clinical outcomes of COVID-19 patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Wang KC, Xiao R, Cheung ZB, et al. | J Orthop
Aim: To assess the risk of early mortality in hip fracture patients with COVID-19 infection who undergo surgical intervention.
CLINICAL CHARACTERISTICS
11/25/20
Li B, Zhang S, Zhang R, et al. | Front Pediatr
Aim: To evaluate the epidemiological spectrum and clinical characteristics of children infected with SARS-CoV-2.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Paul D, Gupta A, Maurya AK | PLoS One
Aim: To evaluate research done, prior to COVID-19 pandemic, on various decontamination methods for reprocessing of N95-FFRs.
RECENTLY UPDATED
INFECTION CONTROL
11/25/20
Nearchou F, Flinn C, Hennessy E, et al  | Int J Environ Res Public Health
Aim: To provide a systematic review of the evidence on the COVID-19 pandemic's impact on youth mental health.
RECENTLY UPDATED
MENTAL HEALTH
11/25/20
Lee Y, Kirubarajan A, Patro N, et al. | Am J Surg
Aim: To assess all research literature related to changes in surgical practice during disease outbreaks and epidemics, especially during the current COVID-19 pandemic.
INFECTION CONTROL
11/25/20
Jiménez D, García-Sanchez A, Rali P, et al. | Chest
Aim: To review the evidence on the incidence of VTE and bleeding among hospitalized patients with COVID-19?
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Saniasiaya J, Islam MA, Abdullah B | Laryngoscope
Aim: To estimate the overall pooled prevalence of olfactory dysfunction in COVID-19 patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Singh AK, Jena A, Kumar-M P, et al. | United European Gastroenterol J
Aim: To review the evidence on the risk of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection and clinical outcomes of coronavirus disease (COVID-19) in inflammatory bowel disease.
CLINICAL CHARACTERISTICS
11/25/20
Galanis P, Vraka I, Fragkou D, et al. | J Hosp Infect
Aim: To determine the seroprevalence of SARS-CoV-2 antibodies among HCWs, and to find out the factors that are associated with this seroprevalence.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/25/20
Katsanos AH, Palaiodimou L, Zand R, et al. | Ann Neurol
Aim: To evaluate the potential impact of coronavirus disease (COVID-19) on the management and outcomes of acute stroke.
CLINICAL CHARACTERISTICS
11/24/20
France R, Vseteckova J, Lapwood S, et wood | CEBM
11/24/20
Novoa RH, Quintana W, Llancarí P, et al. | Travel Med Infect Dis
Aim: To review all cases from the current literature and provide up-to-date scientific evidence on the clinical characteristics, maternal outcomes, perinatal outcomes and the possibility of vertical transmission in the infected pregnant women.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/24/20
Perveen RA, Nasir M, Talha KA, et al. | Med J Malaysia
Aim: To evaluate the effectiveness of antiviral therapies in the treatment of COVID-19.
CANDIDATE THERAPEUTICS
11/20/20
Takla M, Jeevaratnam K | Saudi Pharm J
Aim: To systematically identify and collate 24 studies describing the use of CQ and HCQ in human clinical trials and to provide a detailed synthesis of evidence of its efficacy and safety.
CANDIDATE THERAPEUTICS
11/20/20
Turkistani K & Turkistani K | J Int Soc Prev Community Dent
Aim: To provide dentists and dental auxiliary with insights regarding risk and precautions during COVID-19 crisis.
INFECTION CONTROL
11/20/20
Abdo C, Miranda EP, Santos CS, et al. | Indian J Psychiatry
Aim: To perform a systematic review of the literature regarding the consequences of severe acute respiratory syndrome-CoV-2 infection in terms of domestic violence and substance abuse, and compare incidences found.
MENTAL HEALTH
11/20/20
Park S, Lee Y, Michelow IC, et al. | Open Forum Infect Dis
Aim: To systematically address the global seasonal patterns of human coronavirus (HCoV) infections.
INFECTION CONTROL
11/20/20
Bin Arif T, Khalid S, Siddiqui MS, et al. | Hong Kong Med J
Aim: To provide insight into the incidence, patterns, risk factors, histopathological findings, and relationship with disease severity of COVID-19-associated liver injury.
CLINICAL CHARACTERISTICS
11/20/20
Robertson LJ, Maposa I, Somaroo H, et al. | S Afr Med J
Aim: To understand which mental health conditions may occur in healthcare workers and which interventions could be considered during the COVID-19 pandemic.
MENTAL HEALTH
11/20/20
Liu D, Baumeister RF, Zhou Y | J of Psychiatric Res
Aim: To examine how the mental status of SARS survivors changed after infection and after hospital release.
MENTAL HEALTH
11/20/20
Nunes JPL | Porto Biomed J
Aim: To perform a systematic review on mortality associated to the use of ACEi in patients with COVID-19 disease.
CANDIDATE THERAPEUTICS
11/20/20
Vijenthira A, Gong IY, Fox TA, et al. | Blood
Aim: To perform a systematic review and meta-analysis to estimate the risk of death and other important outcomes for patients with hematologic malignancy infected with COVID-19 .
CLINICAL CHARACTERISTICS
11/20/20
Bwire GM, Njiro BJ, Mwakawanga DL, et al. | Med Virol
Aim: To determine the likelihood of vertical transmission among COVID?19 exposed infants and determine whether antibodies against SARS?CoV?2 were generated among COVID?19 vertically exposed but negative infants.
INFECTION CONTROL
11/20/20
Wang C, Zhang H, Zhou M, et al. | Eur Rev Med Pharmacol Sci
Aim: To explore the relationship between the prognosis of COVID-19 patients and thromboembolic events.
CLINICAL CHARACTERISTICS
11/20/20
Gómez-Durán EL, Martin-Fumadó C, Forero CG.  | Occup Environ Med
Aim: To summarise the research evidence on the psychological impact of quarantine on healthcare workers.
MENTAL HEALTH
11/20/20
Faraone I, Labanca F, Ponticelli M, et al. | Molecules
Aim: To analyze preclinical and clinical studies on HCQ potential use in viral infection and chronic diseases.
CANDIDATE THERAPEUTICS
11/20/20
Younes S, Younes N, Shurrab F, et al. | Rev Med Virol
Aim: To compile and discuss all articles that describe experimental or natural infections with SARS-CoV-2.
INFECTION CONTROL
11/20/20
Dorantes-Acosta E, Ávila-Montiel D, Klünder-Klünder M, et al. | Bol Med Hosp Infant Mex
Aim: To analyze the available data associated with COVID-19 infection and mortality in pediatric cancer patients and to provide useful information to plan and design strategies in this group.
CLINICAL CHARACTERISTICS
11/20/20
Zreiq R, Haouas N, Khemakhem AM, et al. | J of Pharmaceutical Res
Aim: To review the "state-of-the-art" of treatment modalities and propose a practical therapeutic algorithm for the COVID-19 management.
CANDIDATE THERAPEUTICS
11/20/20
Zhao M, Lu J, Tang Y, et al. | Eur J Clin Pharmacol
Aim: To explore the effectiveness and safety of tocilizumab recently used for treating COVID-19.
CANDIDATE THERAPEUTICS
11/20/20
Sánchez OR, Vale DB, Rodrigues L, et al. | Int J Gynaecol Obstet
Aim: To analyze the existing scientific literature on strategies and recommendations to respond to VAW during the implementation of social distancing measures in response to the COVID-19 pandemic.
MENTAL HEALTH
11/20/20
National Collaborating Centre for Methods and Tools | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the risk of COVID-19 transmission across different indoor settings in the community.
INFECTION CONTROL
11/19/20
Mair M, Singhavi H, Pai A, et al. | Laryngoscope
Aim: To examine the pooled prevalence of symptoms, laboratory tests, and imaging of all COVID-19 infected patients.
11/19/20
Alves GS, Casali ME, Veras AB, et al. | Front Psychiatry
Aim: To discuss psychoeducation measures and brief psychosocial interventions designed in a home setting.
MENTAL HEALTH
11/19/20
Kashour T, Abdulhak AAB, Tlayjeh H, et al. | Am J Ther
Aim: To review the evidence on the association between prior use of ACEIs and ARBs and mortality due to COVID-19 disease.
CLINICAL CHARACTERISTICS
11/19/20
Ouyang L, Gong Y, Zhu Y, et al. | Am J Emerg Med
Aim: To explore the relationship of acute kidney injury (AKI) with the severity and mortality of coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
11/19/20
Kubjane M, McCreedy N, Cariou B, et al. | Endocrinol Metab
Aim: To investigate the association between diabetes and COVID-19 disease severity in patients hospitalized due to COVID-19.
CLINICAL CHARACTERISTICS
11/19/20
Cheruiyot I, Kipkorir V, Ngure B, et al. | Am J Emerg Med
Aim: To evaluate whether malignancies are associated with a significantly enhanced odds of COVID-19 severity and mortality.
CLINICAL CHARACTERISTICS
11/19/20
Lim ZJ, Subramaniam A, Reddy MP, et al. | Am J Respir Crit Care Med
Aim: To examine the case fatality rate of patients with COVID-19 receiving invasive medical ventilation.
CANDIDATE THERAPEUTICS
11/19/20
Udomsinprasert W, Jittikoon J, Sangroongruangsri S, et al. | J Clin Immunol
Aim: To determine associations of circulating levels of inflammatory cytokines with severity and mortality of COVID-19 by systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
11/19/20
Sze S, Pan D, Nevill CR, et al. | EClinicalMedicine
Aim: To determine whether the risk of SARS-CoV-2 infection, COVID-19 intensive care unit (ICU) admission and mortality are associated with ethnicity. 
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/19/20
Meng M, Zhao Q, Kumar R, et al. | Aging
Aim: To review the evidence on the effects of coronary heart disease (CHD), hypertension and diabetes on the development of severe COVID-19. 
CLINICAL CHARACTERISTICS
11/19/20
Goldstein KM, Ghadimi K, Mystakelis H, et al. | VA Evidence Synthesis Program
Aim: To review the evidence on the risk of transmitting SARS-CoV-2, SARS, MERS, and influenza with administration of drugs via nebulizer
RECENTLY UPDATED
VA ESP
11/19/20
Beaudry G, Zhong S, Whiting D, et al. | BMJ Glob Health
Aim: To synthesise the evidence on outbreaks of highly contagious diseases in prison.
RECENTLY UPDATED
INFECTION CONTROL
11/19/20
Liaw J, Saadi R, Patel VA, et al. | Otol Neurotol
Aim: To systematically review the available medical literature to investigate the viral load in the middle ear and mastoid cavity and the potential risk of exposure to airborne viruses during otologic surgery.
INFECTION CONTROL
11/19/20
Yang J, Tian C, Chen Y, et al. | J Med Virol
Aim: To explore the relationship between obesity and COVID-19.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/19/20
Li X, Liu C, Mao Z, et al. | Crit Care
Aim: To evaluate the predictive values of NLR on disease severity and mortality in COVID-19 patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/19/20
Mehraeen E, Salehi MA, Behnezhad F, et al. | Infect Disord Drug Targets
Aim: To review the current evidence of COVID-19 transmission modes.
INFECTION CONTROL
11/19/20
Wu T, Zou Z, Yang D, et al. | Age Aging
Aim: To explore the factors associated with prevalence of venous thromboembolism (VTE) in COVID-19 patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
11/18/20
Galli F, Pozzi G, Ruggiero F, et al. | Front Psychiatry
Aim: To provide evidence of the psychopathologic burden on health care workers (HCWs) of the first two deadly coronavirus outbreaks to get lessons for managing the current burden of COVID-19 outbreak.
MENTAL HEALTH
11/18/20
Serafim RB, Póvoa P, Souza-Dantas V, et al. | Clin Microbiol Infect
Aim: To describe the clinical course and outcomes of COVID-19 pneumonia in critically ill patients.
RECENTLY UPDATED
11/18/20
Abdulla S, Hussain A, Azim D, et al. | Cureus
Aim: To draw generalized conclusions regarding impaired liver biochemistry and its potential relationship with COVID-19 disease severity.
CLINICAL CHARACTERISTICS
11/18/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence for transmission of COVID-19 in different settings, and to determine which settings are high risk.
11/18/20
Spencer N, Nathawad R, Arpin E, et al. | BMJ Paediatr Open
Aim: To review the evidence on the impact of pandemics on existing inequities in routine vaccination coverage.
11/18/20
Fischer R, Bortolini T, Karl JA, et al. | Front Psychol
Aim: To provide a broad summary of the current evidence drawn from published meta-analyses in order to evaluate the effectiveness of self-guided therapeutic practices which can be implemented by individuals on their own, including during physical distancing and quarantine measures.
MENTAL HEALTH
11/18/20
Koshy AN, Murphy AC, Farouque O, et al. | Intern Med J
Aim: To investigate whether RAS inhibitors increased the likelihood of a positive test or death/severe illness in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/18/20
Kaye A, Siegel R | PeerJ
Aim: To investigate and synthesize existing evidence for the efficacy of TCZ in reducing COVID-19 mortality.
RECENTLY UPDATED
CANDIDATE THERAPEUTICS
11/18/20
Ramos CCR, Roque JLA, Sarmiento DB, et al. | Int J Health Sci
Aim: To review the literature on the use of ultraviolet-C (UV-C) sterilization to assess its clinical efficacy in reducing risk and transmission of nosocomial infections as well as its associated health safety or hazards.
INFECTION CONTROL
11/16/20
Raharja A, Tamara A, Kok LT | J Racial Ethn Health Disparities
Aim: To review the association between ethnicity and poor Covid-19 outcomes including all-cause mortality, hospitalisation, critical care admission, respiratory and kidney failure.
UPDATED
CLINICAL CHARACTERISTICS
11/16/20
Wong CKH, Wong JYH, Tang EHM, et al. | Sci Rep
Aim: To investigate the comorbidities, symptoms, clinical characteristics and treatment of COVID-19 patients. 
UPDATED
CLINICAL CHARACTERISTICS
11/16/20
Joseph B, Dibas M, Evanson KW, et al. | Expert Rev Anti Infect Ther
Aim: To systematically review the clinical literature reporting the use of Lopinavir/ritonavir (LPV/r) for the treatment of patients with COVID-19 to assess the efficacy of LPV/r for the treatment of Cornonavirus disease 19 (COVID-19).
CANDIDATE THERAPEUTICS
11/16/20
Juhasz MF, Ocskay K, Kiss S, et al. | World J Gastroenterol
Aim: To assess all the available evidence in the literature relating to coronavirus disease 2019 (COVID-19) and AP.
CLINICAL CHARACTERISTICS
11/16/20
Akin H, Kurt R, Tufan F, et al. | Diseases
Aim: Too present the currently available data regarding the GI symptoms of COVID-19 patients, and to compare the frequency of GI symptoms in early stage (Eastern) mostly Chinese data to the current stage (Western) non-Chinese data. 
CLINICAL CHARACTERISTICS
11/16/20
Pant S, Perras C | CADTH
Aim: To describe the trial characteristics and estimated primary completion dates of the ongoing phase II, phase III, and phase IV studies evaluating drugs to prevent or treat COVID-19.
UPDATED
11/16/20
Bustos R, Jaramillo-Bustamante JC, Vasquez-Hoyos P, et al. | Pediatr Emerg Care
Aim: To review the evidence on pediatric inflammatory multisystem syndrome associated with SARS-CoV-2.
CLINICAL CHARACTERISTICS
11/16/20
Pinedo-Torres I, Flores-Fernandez M, Yovera-Aldana M, et al. | Clin Med Insights Endocrinol Diabetes
Aim: To determine the prevalence of diabetes comorbidity and its associated unfavorable health outcomes in patients with acute respiratory syndromes for coronavirus disease according to virus types.
UPDATED
CLINICAL CHARACTERISTICS
11/13/20
Haiduc AA, Ogunjimi M, Shammus R, et al. | Cardiol Young
Aim: To examine the literature to determine if both paediatric and adult patients diagnosed with congenital heart disease (CHD) are at a higher risk of poor outcomes if they have the coronavirus disease 2019 (COVID-19), compared to those without CHD.
CLINICAL CHARACTERISTICS
11/13/20
Kubota T, Kuroda N | Clin Neurol Neurosurg
Aim: To evaluate the severity of COVID-19 and its effect on neurological symptoms in patients with preexisting neurological disorder and COVID-19.
CLINICAL CHARACTERISTICS
11/13/20
Lin L, Wang X, Ren J, et al. | BMJ Open
Aim: To analyse the incidence, risk factors and impact of acute kidney injury (AKI) on the prognosis of patients with COVID-19.
CLINICAL CHARACTERISTICS
11/12/20
Wang K, Wu C, Xu J, et al. | EClinicalMedicine
Aim: To describe the clinical outcomes of operative patients with COVID-19, and the safety of medical staff during the perioperative period to take appropriate protective measures to avoid cross-infection.
11/12/20
Fredericks S, Miranda J, Sidani S, et al. | Brain Behav Immun Health
Aim: To inform evidence-based decision-making pertaining to the selection of effective strategies or therapies that this cohort could use to promote mental health and resilience both within the clinical practice and academic environment.
11/12/20
Hong TS, Gonzalez J, Nahass RG, et al. | Pharmacy
Aim: To evaluate the impact of HCQ exposure on mortality in hospitalized patients with COVID-19. 
11/11/20
Kuswardhani RAT, Henrina J, Pranata R, et al. | Diabetes Metab Syndr
Aim: To assess the association between CCI and a composite of poor outcomes in COVID-19 patients.
CLINICAL CHARACTERISTICS
11/11/20
Mahalingasivam V, Carik A, Tomlinson LA, et al. | Kidney Int Rep
Aim: To synthesise, analyse and appraise what has been learnt so far to help clinicians and policy makers better understand the risks to kidney transplant recipients, as well as identify gaps for future collaborative research for this global health challenge.
UPDATED
INFECTION CONTROL
11/11/20
Tleyjeh IM, Kashour Z, Damlaj M, et al. | Clin Microbiol Infect
Aim: To perform a living systematic review of the literature about the efficacy and toxicity of the IL-6 receptor antagonist, tocilizumab, in COVID-19 patients.
CANDIDATE THERAPEUTICS
11/11/20
Oscanoa TJ, Vidal X, Kanters JK, et al. | Int J Antimicrob Agents
Aim: To conduct a meta-analysis of the frequency of LQT in patients with SARS-CoV-2 infection treated with HCQ.
CANDIDATE THERAPEUTICS
11/11/20
Aziz M, Haghbin H, Lee-Smith W, et al. | Ann Gastroenterol
Aim: To review the evidence on the gastrointestinal predictors of severe COVID-19.
CLINICAL CHARACTERISTICS
11/11/20
Choi Y, Lee MK | Eur J Radiol
Aim: To comprehensively evaluate the incidences of abnormal neuroimaging findings in patients with COVID-19 via a systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
11/11/20
Mudatsir M, Fajar JK, Wulandari L, et al. | F1000
Aim: To identify the predictors associated with poor clinical outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/11/20
Cachon-Zagalaz J, Sanchez-Zafra M, Sanabrias-Moreno D, et al. | Front Psychol
Aim: To learn about the research carried out on the child population in times of confinement, especially those dealing with the psychological and motor aspects of minors.
MENTAL HEALTH
11/11/20
Tleyjeh I, Kashour Z, Al Dosary O, et al. | Mayo Clin Proc Innov Qual Outcomes
Aim: To systematically review the literature and estimate the risk of cardiac toxicity in patients receiving CQ or HCQ for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/11/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on monitoring wastewater as a surveillance strategy for COVID-19.
11/9/20
Ren L, Xu W, Overton JL, et al. | Front Pharmacol
Aim: To examine the safety profiles of these medications, we systematically evaluated the adverse events (AEs) of these medications from published randomized controlled trials (RCTs).
UPDATED
CANDIDATE THERAPEUTICS
11/9/20
Alimohamadi Y, Sepandi M, Taghdir M, et al.  | J Prev Med Hyg
Aim: To estimate the prevalence of clinical symptoms of COVID-19 in a systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
11/9/20
Mekonnen D, Mengist HM, Derbi A, et al.  | Rev Med Virol
Aim: To assess the diagnostic test accuracy (DTA) of severe acute respiratory syndrome coronavirus 2 (SARS?COV?2) serological test methods and the kinetics of antibody positivity. 
DIAGNOSTICS
11/9/20
Ye L, Yang Z, Liu J, et al. | J Gastroenterol Hepatol
Aim: To highlight the gaps in our knowledge about the prevalence and clinical significance of GI symptoms in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/9/20
Jeevananthan C, Muhamed NA, Jafaar MH, et al. | BMJ Open
Aim: To identify the effects of temperature, humidity and air quality in the transmission of SARS-CoV-2 and to determine if the effects are linked to anthropic activities.
UPDATED
INFECTION CONTROL
11/9/20
Lebrasseur A, Fortin-Bedard N, Lettre J, et al.  | Disabil Health J
Aim: To review the impact of the COVID-19 pandemic, and associated isolation and protective measures, among people with physical disabilities.
UPDATED
MENTAL HEALTH
11/9/20
Yue J, Yan W, Sun Y, et al. | Psychol Med
Aim: To review the available data on the benefits of interventions to reduce adverse mental health sequelae of infectious disease outbreaks, and to offer guidance for mental health service responses to infectious disease pandemic.
MENTAL HEALTH
11/9/20
Aggarwal K, Agarwall A, Jaiswal N, et al.  | PLoS ONE
Aim: To evaluate the epidemiology and clinical features of ocular surface manifestations and complications related to COVID-19 infection, to assess the risk of transmission to patients and healthcare workers through ocular secretions and to determine whether ocular involvement has any correlation with the severity of respiratory symptoms and overall prognosis.
UPDATED
CLINICAL CHARACTERISTICS
11/9/20
Hasan I, Rashid T, Suliman S, et al. | Rom J Intern Med
Aim: To review the evidence on COVID-19 in kidney transplant recipients.
CLINICAL CHARACTERISTICS
11/9/20
Ssentongo A, Ssentongo P, Heilbrunn E, et al | Open Heart
Aim: To explore the association of RAAS inhibitors, including angiotensin-converting inhibitors (ACEi) and angiotensin II receptor blockers (ARBs) with COVID-19 mortality in patients with hypertension. 
UPDATED
CLINICAL CHARACTERISTICS
11/9/20
Kiss P, Carcel C, Hockham C, et al. | Eur Heart J Qual Care Clin Outcomes
Aim: To assess the extent to which health services related to the care and management of acute cardiovascular events have been impacted during the COVID-19 pandemic.
11/9/20
Matsushita K, Ding N, Kou M, et al. | Glob Heart
Aim: To explore pre-existing CVD and its traditional risk factors as risk factors of severe COVID-19 (defined as death, acute respiratory distress syndrome, mechanical ventilation, or intensive care unit admission). 
UPDATED
CLINICAL CHARACTERISTICS
11/9/20
Sridharan GK,  Vegunta R, Rokkam VRP, et al. | Am J Ther
Aim: To examine and appraise the incidence of VTE, major VTE, PE, and DVT in hospitalized COVID-19 patients by meta-analysis methods and, in particular, analyze whether the use of therapeutic anticoagulation decreased the odds of thromboembolic events compared with prophylactic anticoagulation.
CLINICAL CHARACTERISTICS
11/6/20
Santos M, Torres D, Cardoso PC, et al. | Braz Oral Res
Aim: To investigate the efficiency of cloth masks in reducing transmission and contamination by droplets and aerosols for the general population and healthcare workers.
11/6/20
Mallett S, Allen J, Graziadio S, et al. | BMC Med
Aim: To examine at what time points during SARS?CoV?2 infection it is detectable at different anatomical sites using RT?PCR based tests.  
UPDATED
11/6/20
Yadav R, Srivastava DK, Bajpai PK, et al. | J Neurosci Rural Pract
Aim: To determine the neurological involvement and its manifestations in COVID-19 patients.
11/6/20
Pereira M, Damascena AD, Azevedo LMG, et al. | Crit Rev Food Sci Nutr
Aim: To analyze the association between vitamin D deficiency and COVID-19 severity, via an analysis of the prevalence of vitamin D deficiency and insufficiency in people with the disease. 
11/5/20
Mirza FN, Malik AA, Omer SB, et al. | Int J Dermatol
Aim: To collate the available information on the dermatologic manifestations in COVID?19 patients to inform current practice and further research.
UPDATED
11/5/20
Cheruiyot I, Sehmi P, Ominde B, et al  | Neurol Sci
Aim: To identify and consolidate evidence of ICH in COVID-19 patients.
11/5/20
Alamoodi AH, Zaidan BB, Zaidan AA, et al. | Expert Syst Appl
Aim: To review and analyse articles about the occurrence of different types of infectious diseases, such as epidemics, pandemics, viruses or outbreaks, during the last 10 years, understand the application of sentiment analysis and obtain the most important literature findings.
11/4/20
Park R, Lee S, Kim SY, et al  | Acta Oncol
Aim: To summarize the existing evidence for the effect of active oncologic treatment on COVID-19 outcomes.
UPDATED
11/4/20
Zhang H, Han H, He T, et al. | J Natl Cancer Inst
Aim: To review the evidence on the reported fatalities in COVID-19 patients with cancer.
11/4/20
Hessami K, Romanelli C, Chiurazzi M, et al. | J Matern Fetal Neonatal Med
Aim: To evaluate the effect of the COVID-19 pandemic on anxiety and depression of women during pregnancy and perinatal period.
MENTAL HEALTH
11/4/20
Cao K, Kline B, Han Y, et al. | Biomed Res Int
Aim: To estimate the prevalence rate of ocular symptoms and the positive rate of conjunctival swab samples of patients diagnosed with 2019 Novel Coronavirus Disease (COVID-19).
11/4/20
 | NSW Health COVID-19 Critical Intelligence Unit
11/4/20
Hoang T | J Med Virol
Aim: To summarize the current evidence of factors associated with the risk of disease recurrence.
11/4/20
Vizheh M, Qorbani M, Arzaghi SM, et al. | J Diabetes Metab Disord
Aim: To review all research carried out on the mental health status of health care workers (HCWs) to bring policymakers and managers’ attention.
MENTAL HEALTH
11/4/20
Khateri S, Mohammadi H, Khateri R, et al. | Arch Acad Emerg Med
Aim: To determine the prevalence of underlying diseases and associated comorbidities in COVID-19 patients using a systematic review and meta-analysis.
11/4/20
Bashash D, Hosseini-Baharanchi FS, Rezaie-Tavirani M, et al. | Arch Acad Emerg Med
Aim: To provide a well-conceptualized viewpoint demonstrating the prognostic value of thrombocytopenia in COVID-19.
11/3/20
O'Neil M, Veazie S, LaFavor B | VA Evidence Synthesis Program
Aim: To compare the prevalence of mental health disorders among adults who have been hospitalized for COVID-19 to relevant comparison groups, assess whether the prevalence of mental health disorders varies by patient and disease characteristics, and ascertain mental health care utilization and resource needs for adults following hospitalization for COVID-19.
UPDATED
VA ESP
MENTAL HEALTH
11/2/20
Boregowda U, Perisetti A, Nanjappa A, et al. | Front Med
Aim: To compare the efficacy of tocilizumab in severe COVID-19 cases vs. standard of care alone.
UPDATED
11/2/20
Dawoud DM, Soliman KY | Value Health
Aim: To review published economic evaluations of antiviral treatment for pandemics and outbreaks of respiratory illnesses.
11/2/20
Saad MA, Alfishawy M, Nassar M, et al. | Curr Rheumatol Rev
Aim: To review the evidence on reported COVID-19 cases with asociated autoimmune manifestations.
11/2/20
Palaiodimos L, Chamorro-Pareja N, Karamanis D, et al. | Hormones
Aim: To systematically review and synthesize with a meta-analysis the available observational studies reporting the effect of diabetes in mortality among hospitalized patients with COVID-19.
UPDATED
11/2/20
Elsawah H, Elsokary M, Abdallah MS, et al. | Rev Med Virol
Aim: To systematically review the use of remdesivir in Covid?19 among the available clinical trials and summarise remdesivir efficacy.
UPDATED
11/2/20
Hariyanto TI, Kristine E, Jillian C, et al. | Infect Disord Drug Targets
Aim: To review the evidence on the use of lopinavir/ritonavir as a potential treatment candidate against COVID-19.
11/2/20
Megnin-Viggars O, Carter P, Melendez-Torres GJ, et al. | PLoS One
Aim: To identify facilitators and barriers to uptake of, and engagement with, contact tracing during infectious disease outbreaks.
11/2/20
Prasitlumkum N, Chokesuwattanaskul R, Thongprayoon C, et al. | Diseases
Aim: To explore the incidence of acute myocardial injury among COVID-19 patients.
11/2/20
Cagnazzo F, Arquizan C, Derraz I, et al. | J Neurol
Aim: To perform an updated review of the literature on the neurological manifestations of COVID-19-infected patients
11/2/20
Trypsteen W, Van Cleemput J, Van Snippenberg W, et al. | PLoS One
Aim: To review the current (pre)published SARS-CoV-2 literature with a focus on the evidence concerning SARS-CoV-2 distribution in human tissues and viral shedding in body fluids.
11/2/20
Shrestha DB, Budhathoki P, Syed N, et al. | Life Sci
Aim: To conduct a systematic review and meta-analysis on remdesivir use for COVID-19.
11/2/20
Ciaffi J, Meliconi R, Ruscitti P, et al. | BMC Rheumatol
Aim: To assess the prevalence of rheumatic manifestations in patients affected by COVID-19, as initial symptom or during disease course.
11/2/20
Lee KW, Khan AHKY, Ching SW, et al. | Front Neurol
Aim: To perform a systematic review and meta-analysis of currently available epidemiological, clinical, and laboratory data related to both stroke and COVID-19 infection.
11/2/20
Violante T, Violante FS | Med Lav
Aim: To summarize the available studies which have compared the respective effectiveness of surgical masks and filtering facepiece respirators  for the prevention of infections caused by viruses that are transmitted by the respiratory tract.
11/2/20
Antony AR, Haneef Z | Seizure
Aim: To synthesize the data on EEG findings in COVID-19.
11/2/20
Kolcun JPG, Ryu WHA, Traynelis VC | J Neurosrug Spine
Aim: To examine the current utilization of TM for spine surgery.
11/2/20
Del Riccio M, Lorini C, Bonaccorsi G, et al. | Int J Environ Res Public Health
Aim: To review the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g. severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients.
UPDATED
11/2/20
Chen J, Wu C, Wang X, et al. | Front Endocrinol
Aim: To summarize available data on the association between glycemic parameters and severity of COVID-19.
10/30/20
Ghayda RA, Li H, Lee KH, et al. | J Clin Med
Aim: To synthesize the most up-to-date and relevant available evidence on the outcomes of pregnant women with laboratory-confirmed infection with COVID-19.
CLINICAL CHARACTERISTICS
10/30/20
Ebrahimi M, Malehi AS, Rahim F | Osong Public Health Res Perspect
Aim: To compare coronavirus disease 2019 (COVID-19) laboratory findings, comorbidities, and clinical outcomes in patients from the general population versus medical staff to aid diagnosis of COVID-19 in a more timely, efficient, and accurate way.
DIAGNOSTICS
10/30/20
D'Errico S, Zanon M, Montanaro M, et al. | Microorganisms
Aim: To summarize all autopsy studies up to February 2020 in which a complete post-mortem investigation in patients with COVID-19 disease was performed, focusing on histopathological features. 
CLINICAL CHARACTERISTICS
10/30/20
Andrenelli E, Negrini F, De Sire A, et al. | Eur J Phys Rehabil Med
Aim: To report data of a systematic search performed on papers published in July 2020.
UPDATED
CLINICAL CHARACTERISTICS
10/30/20
Dong Z, Xiang B, Jiang M, et al. | Clin Gastroenterol
Aim: To investigate the prevalence of GI symptoms, abnormal liver function, digestive system disease and liver disease in patients with COVID-19 by a systematic review and meta-analysis.
CLINICAL CHARACTERISTICS
10/30/20
Arora T, Grey I, Ostlundh L, et al. | J Health Psychol
Aim: To examine the overall prevalence of psychological health outcomes during COVID-19. 
UPDATED
MENTAL HEALTH
10/29/20
Munteanu C, Paun D, Suta A, et al. | Balneo Research Journal
Aim: To identify the main possible interferences between DM and COVID-19's pathological mechanisms, and to discuss the value of physical and rehabilitation medicine and balneotherapy in the post-acute COVID-19 recovery of the surviving patients
CLINICAL CHARACTERISTICS
10/29/20
Aggarwal G, Lippi G, Lavie CJ, et al.  | J Diabetes
Aim: To evaluate the potential assocations between diabetes mellitus and infection severity outcomes in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/29/20
Patel U, Malik P, Mehta D, et al. | J Glob Health
Aim: To evaluate epidemiological characteristics, needs of resources, outcomes, and global burden of the disease.
10/29/20
Khan M, Khan N, Mustagir G, et al. | J Glob Health
Aim: To summarize pre-existing comorbidities in patients with COVID-19, and to estimate the likelihood of mortality from COVID-19 with each category of pre-existing comorbidities.
UPDATED
CLINICAL CHARACTERISTICS
10/29/20
Kumar R, Nedungalaparambil NM, Mohanan N | J Family Med Prim Care
Aim: To review the evidence on emergency and primary care collaborations during the COVID-19 pandemic.
10/29/20
PHAC Emerging Science Group | Public Health Agency of Canada
Aim: To review the evidence on whether hosptialized SARS-CoV-2 patients that successfully recover with no subsequently positive RT-PCR tests present with SARS-CoV-2 antibody levels or seropositivity rates differ from those that do retest positive?
10/29/20
Ramos-Lopez O, Daimiel L, de Molina AR, et al. | Int J Genomics
Aim: To systematically explore genetic polymorphisms associated with the clinical outcomes in SARS-CoV infection in humans.
CLINICAL CHARACTERISTICS
10/29/20
Mohammadi M, Rajabnia M, Abdehagh M | Sci J Kurd Univ Med Sci
Aim: To review the gastrointestinal manifestations in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/29/20
Hasan I, Saif-Ur-Rahman KM, Hayat S, et al. | J Peripher Nerv Syst
Aim: To summarize and meta?analyze the salient features and prognosis of SARS?CoV?2?associated GBS.
CLINICAL CHARACTERISTICS
10/29/20
Ling XC, Kang EY, Lin J, et al. | Taiwan J Ophthalmol
Aim: To provide general guidance for ophthalmologists to understand the prevalence of ocular presentation in COVID 19 patients and to reduce the risk of transmission during practice.
INFECTION CONTROL
10/29/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the effectiveness of fit testing and fit checking for testing the protection of a respirator.
10/29/20
Milby KM, Atallah AN, Rocha-Filho CR, et al. | Sao Paulo Med J
Aim: To understand and summarize the evidence relating to clinical manifestations, disease severity and prognoses among patients coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and arboviruses.
UPDATED
CLINICAL CHARACTERISTICS
10/29/20
Jahrami H, BaHammam AS, Bragazzi NL, et al. | J Clin Sleep Med
Aim: To assess the impact and prevalence of sleep problems among the general population, healthcare workers, and COVID-19 patients.
MENTAL HEALTH
10/28/20
Comber L, Murchu EO, Drummond L, et al. | Rev Med Virol
Aim: To synthesise the evidence for the potential airborne transmission of SARS-CoV-2 via aerosols.
INFECTION CONTROL
10/28/20
Mora-Ramirez M, Melgoza-Hernandez P, Toledo-Ramirez SE, et al. | Curr Med Chem
Aim: To review the main adverse effects regarding the most prescribed drugs and, specifically, the efficacy and potential risk of each pharmacological therapy, during hospital care for COVID-19.
CANDIDATE THERAPEUTICS
10/28/20
Chou R, Dana T, Jungbauer R, et al. | Ann Intern Med
Aim: To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.
UPDATED
10/28/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the contributing factors of a second spike in COVID-19 cases.
10/28/20
Amanullah S, Shankar RR | Healthcare
Aim: To analyse and summarise the current knowledge on factors/potential factors contributing to burnout amongst healthcare professionals amidst the pandemic. 
MENTAL HEALTH
10/27/20
Wijeratne T, Sales C, Karimi L, et al.  | Front Neurol
Aim: To review the clinical data on all published cases of COVID-19 and concomitant AIS, with a view to understanding the pertinent clinical, laboratory and imaging features.
CLINICAL CHARACTERISTICS
10/27/20
Lu Q, Wang Z, Yin Y, et al. | Front Med
Aim: To investigate the evidence on the association between peripheral lymphocyte levels and the progression and mortality of COVID-19.
CLINICAL CHARACTERISTICS
10/27/20
Budhathoki P, Shrestha DB, Rawal E, et al. | SN Compr Clin Med
Aim: To assess the rationality on the use of corticosteroids in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/27/20
Nannoni S, de Groot R, Bell S, et al.  | Int J Stroke
Aim: To characterize the incidence, risk factors, clinical-radiological manifestations and outcome of COVID-19-associated stroke.
CLINICAL CHARACTERISTICS
10/27/20
Hojaij FC, Chinelatto LA, Boog GHP, et al.  | Int Arch Otorhinolaryngol
Aim: To provide an easy access to and a trustful review of the main aspects that have changed in the head and neck surgery and otorhinolaryngology practice due to the COVID-19 pandemic.
INFECTION CONTROL
10/27/20
Mackey K, King VJ, Gurley S, et al. | VA Evidence Synthesis Program
Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.
UPDATED
WHO COLLABORATIVE
VA ESP
10/27/20
Mehraeen E, Karimi A, Barzegary A, et al.  | Eur J Integr Med
Aim: To systematically review the assessment of risk and model the predictors of mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/27/20
Chen X, Zhang G, Hao SY, et al. | Chin Med Sci J
Aim: To compare the similarities and differences of early CT manifestations of three types of viral pneumonia induced by SARS-CoV-2 (COVID-19), SARS-CoV (SARS) and MERS-CoV (MERS) using a systemic review.
CLINICAL CHARACTERISTICS
10/27/20
Szegedi I, Orbán-Kálmándi R, Csiba L, et al. | J Clin Med
Aim: To summarize the available literature on COVID-19-associated coagulopathy and thrombosis and to identify the characteristics of stroke in COVID-19.
CLINICAL CHARACTERISTICS
10/27/20
Pranata R, Supriyadi R, Huang I, et al.  | Clin Med Insights Circ Respir Pulm Med
Aim: To evaluate the association between chronic kidney disease (CKD) and new onset renal replacement therapy (RRT) with the outcome of Coronavirus Disease 2019 (COVID-19) in patients.
CLINICAL CHARACTERISTICS
10/27/20
Bansal A, Singh AD, Jain V, et al.  | Heart & Lung
Aim: To determine if D-dimers are elevated in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who have adverse clinical outcomes including all-cause mortality, intensive care unit (ICU) admission or acute respiratory distress syndrome (ARDS).
CLINICAL CHARACTERISTICS
10/27/20
Valencia-Enciso N, Ortiz-Pereira M, Zafra-Sierra MP, et al. | J Stroke Cerebrovasc Dis
Aim: To assess the temporal relationship between COVID-19 severity and stroke onset. To determine if characteristics such as presentation of the stroke, younger age, involvement of large vessel occlusion and pattern of paraclinical markers could be distinct from the no-COVID-19 population.
CLINICAL CHARACTERISTICS
10/26/20
Comber L, Walsh KA, Jordan K, et al. | Rev Med Virol
Aim: To synthesise the available evidence for detection of SARS?CoV?2 RNA using RT?PCR tested saliva or nasal specimens compared with RT?PCR tested nasopharyngeal specimens.
DIAGNOSTICS
10/26/20
Weatherald J, Solverson K, Zuege DJ, et al. | J Crit Care
Aim: To quickly identify and synthesize studies examining the effect of awake prone positioning on patients with hypoxemic respiratory failure (including those with ARDS and/or COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
10/26/20
Zeng L, Wang S, Cai J, et al. | Epidemiol Infect
Aim: To determine the potential risk factors for cardiac injury complicated COVID-19 virus infection.
CLINICAL CHARACTERISTICS
10/26/20
Yee JY, Kim WK, Han JMH, et al. | Sci Rep
Aim: To evaluate the impact of COVID-19 on pregnant women.
UPDATED
CLINICAL CHARACTERISTICS
10/26/20
Mirzaie H, Vahidi M, Shokoohi M, et al. | medRxiv
Aim: To summarize the evidence on COVID-19 patients with HBV or HCV co-infections. 
10/26/20
Mch SA, Baishya M, Singh A, et al. | Trends Anaesthesia Crit Care
Aim: To conduct a systematic review of the available literature to highlight the effect of awake proning on the need for intubation, improvement in oxygenation and mortality rates in COVID-19 patients with ARDS.
CANDIDATE THERAPEUTICS
10/26/20
Hu C, Liang M, Gong F, et al. | Evid Based Complement Alternat Med
Aim: To investigate and compare the therapeutic effect of Lianhua Qingwen with conventional drugs on pneumonia symptoms.
CANDIDATE THERAPEUTICS
10/26/20
Chaabna K, Doraiswamy S, Mamtani R, et al. | Int J Infect Dis
Aim: To inform policymakers and stakeholders by examining and synthesizing available evidence on the effectiveness of cloth and medical facemasks for preventing transmission of respiratory infections in community settings and pointing out the gaps in evidence.
INFECTION CONTROL
10/26/20
Gu ZC, Zhang C, Kong LC, et al. | Cardiovasc Diagn Ther
Aim: To summarize all available evidence for a comprehensive and rigorous systematic review focused on myocardial injury incidence in COVID-19. In addition, to state the case-fatality rate related to cardiac injury, variations of myocardial injury incidence were also examined by disease severity (non-survivors, severe patients, and non-severe patients).
CLINICAL CHARACTERISTICS
10/26/20
Wang H, Ai J, Loeffelholz MJ, et al. | Emerg Microbes Infect
Aim: To evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals.
DIAGNOSTICS
10/26/20
Malik P, Patel U, Patel K, et al. | J Med Virol
Aim: To assess the effect of obesity on outcomes in the COVID-19 hospitalizations.
CLINICAL CHARACTERISTICS
10/26/20
Javanmardi F, Keshavarzi A, Akbari A, et al. | PLoS One
Aim: To evaluate the prevalence of underlying disease in died people with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/26/20
Vazzana N, Dipaola F, Ognibene S | Acta Clin Belg
Aim: To review the prognostic value of procalcitonin for severe disease and adverse outcome events in COVID-19.
CLINICAL CHARACTERISTICS
10/26/20
de Labry-Lima AO, Bermudez-Tamayo C, Martinez-Olmos J, et al. | Enferm Infecc Microbiol Clin
Aim: To compile the available evidence on the use of masks in relation to respiratory infections.
INFECTION CONTROL
10/26/20
Wang Y, Chen B, Li Y, et al. | J Med Virol
Aim: To investigate the effects of ACEI/ARB on COVID-19 patients.
CANDIDATE THERAPEUTICS
10/25/20
Kotak S, Khatri M, Malik M, et al. | Cureus
Aim: To assess the safety and efficacy of tocilizumab as compared to the standard regimen in patients with COVID-19.
CANDIDATE THERAPEUTICS
10/23/20
Bwire GM, Nijiro BJ, Mwakawanga DL, et al. | J Med Virol
Aim: To determine the likelihood of vertical transmission among COVID-19 exposed infants and to determine whether antibodies against Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/ COVID-19 virus exist among COVID-19 vertically exposed but negative infants.
CLINICAL CHARACTERISTICS
10/23/20
La Distia Nora R, Putera I, Khalisha DF, et al. | BMJ Open Ophthalmol
Aim: To review and critically appraise the ocular manifestation and the presence of SARS-CoV-2 through PCR positivity from ocular samples in COVID-19-related patients. Moreover, to evaluate the time and severity association of ocular manifestation to systemic disease of COVID-19.
CLINICAL CHARACTERISTICS
10/23/20
Yamakawa M, Kuno T, Mikami T, et al. | J Stroke Cerebrovasc Dis
Aim: To depict the frequency and clinical characteristics of COVID-19 patients with stroke.
CLINICAL CHARACTERISTICS
10/23/20
Guo L, Shi Z, Zhang Y, et al. | Diabetes Res Clin Pract
Aim: To assess the association of comorbid diabetes with COVID-19 severity or mortality in China.
CLINICAL CHARACTERISTICS
10/23/20
Wang JG, Cui HR, Tang HB, et al. | Sci Rep
Aim: To understand the clinical manifestations and incidence of gastrointestinal symptoms of Coronavirus disease (COVID-19) in children and discuss the importance of fecal nucleic acid testing.
UPDATED
CLINICAL CHARACTERISTICS
10/23/20
Favas TT, Dev P, Chaurasia RN, et al. | Neurol Sci
Aim: To estimate the proportion of COVID-19 patients developing neurological manifestations.
CLINICAL CHARACTERISTICS
10/23/20
Raymond C, Loshak H | CADTH
Aim: To describe the trial characteristics and estimated primary completion dates of the ongoing phase II, phase III, and phase IV studies evaluating IVIg and hyperimmune globulin to treat COVID-19.
UPDATED
10/23/20
Wang C, Zhang H, Zhou Y, et al. | Eur Rev Med Pharmacol Sci
Aim: To explore the relationship between the prognosis of COVID-19 patients and thromboembolic events.
CLINICAL CHARACTERISTICS
10/22/20
Wijaya I, Andhika R, Huang I | Clin Appl Thromb Hemost
Aim: To explore the association between therapeutic-dose anticoagulation and its effect on mortality in patients with COVID-19.
CANDIDATE THERAPEUTICS
10/22/20
Kurdi A, Abutheraa N, Akil L, et al. | Pharmacol Res Perspect
Aim: To provide a comprehensive/updated evaluation of the effect of ACEIs/ARBs on COVID?19?related clinical outcomes, including exploration of interclass differences between ACEIs and ARBs.
CANDIDATE THERAPEUTICS
10/22/20
Fong V, Iarocci G | J Pediatr Psychol
Aim: To evaluate the quality of existing studies on this topic, determine what is known about mental health outcomes and needs of children and families, and provide recommendations for how COVID-19 policies can best support children and families
UPDATED
MENTAL HEALTH
10/22/20
Qadri SK, Ng P, Toh TSW, et al. | Pulm Ther
Aim: To describe the mechanisms of action of prone position, systematically appraise the current experience of prone position in COVID-19 patients, and highlight unique considerations for prone position practices during this pandemic.
CANDIDATE THERAPEUTICS
10/22/20
Sepandi M, Taghdir M, Alimohamadi Y, et al. | Iran J Public Health
Aim: To identify effective factors on the death among COVID-19 patients.
CLINICAL CHARACTERISTICS
10/22/20
Ibrahim W | CNS Spectr
Aim: To systematically assess the neurological manifestations in patients diagnosed with COVID-19
CLINICAL CHARACTERISTICS
10/22/20
Chew QH, Wei KC, Vasoo S, et al. | J Clin Psychiatry
Aim: To learn from past infectious disease outbreaks to provide better psychological support for our frontline health care workers (HCW) by conducting a rapid review of extant studies that have reported on both psychological and coping responses in HCW during recent outbreaks.
MENTAL HEALTH
10/22/20
Perras C, Pohar S, Manoharan A, et al. | CADTH
Aim: To review the current scientific evidence on the potential benefits and harms of remdesivir.
UPDATED
10/22/20
Haradaa G, Antonacio FF, Gongora AB, | Ecancermedicalscience
Aim: To address the question of whether to test asymptomatic cancer patients before initiating systemic cancer treatments.
CLINICAL CHARACTERISTICS
10/22/20
Andrews E, Berghofer K, Long J, et al. | Int J Nurs Adv
Aim: To examine current evidence on patient and healthcare provider's satisfaction with the use of telehealth during the COVID-19 pandemic
INFECTION CONTROL
10/22/20
Ayele Mega T, Feyissa TM, Dessalegn Bosho D, et al. | Can Respir J
Aim: To generate an up-to-date evidence for the clinical safety and efficacy of hydroxychloroquine (HCQ) with or without azithromycin (AZ) among patients treated for COVID-19.
CANDIDATE THERAPEUTICS
10/22/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the role of daycares and schools in the transmission of COVID-19.
UPDATED
10/21/20
Leisman DE, Ronner L, Pinotti R, et al. | Lancet Respir Med
Aim: To synthesise and describe the reported pattern of inflammatory cytokines in COVID-19-induced respiratory failure and to compare this profile with those of other acute inflammatory syndromes.
UPDATED
CLINICAL CHARACTERISTICS
10/21/20
Cheng L, Li H, Li L, et al. | J Clin Lab Anal
Aim: To determine the role of ferritin in COVID?19.
CLINICAL CHARACTERISTICS
10/21/20
Agstam S, Yadav A, Kumar MP, et al. | Indian Pacing Electrophysiol J
Aim: To study the risk of QTc prolongation and Torsades de pointes (TdP) by a well-defined criterion for HCQ, CQ alone, and in combination with Azithromycin in patients with COVID-19.
CANDIDATE THERAPEUTICS
10/21/20
Kefale B, Tegegne GT, Degu A, et al. | Clin Appl Thromb Hemost
Aim: To investigate the extent and risk factors of thromboembolism among COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/21/20
Bhattacharyya A, Kumar S, Sarma P, et al. | Indian J Pharmacol
Aim: To evaluate the safety as well as efficacy of L/R combination therapy in the management of COVID-19.
CANDIDATE THERAPEUTICS
10/21/20
Xu J, Teng Y, Shang L, et al. | Clin Infect Dis
Aim: To provide a comprehensive summarization of current evidence to answer two major clinical questions: (1) Does the prior treatment of ACEI/ARB alter the susceptibility of SARS-CoV-2 infection in general population? (2) Does the prior treatment of ACEI/ARB affect risk of mortality and severe outcomes in COVID-19 patients?
UPDATED
CLINICAL CHARACTERISTICS
10/20/20
da Silva PG, Nascimento MSJ, Soares RRG, et al. | Sci Total Environ
Aim: To review the evidence on the viability/stability of aerosols containing SARS-CoV and MERS-CoV viruses.
INFECTION CONTROL
10/20/20
Yonas E, Alwi I, Pranata R, et al. | Am J Emerg Med
Aim: To investigate the association between heart failure (HF) and poor outcome in patients with COVID-19.
CLINICAL CHARACTERISTICS
10/20/20
Gungor B, Atici A, Baycan OF, et al. | Am J Emerg Med
Aim: To investigate the correlation of D-dimer levels measured on admission with disease severity and the risk of death in patients with coronavirus disease 2019 (COVID-19) pneumonia.
CLINICAL CHARACTERISTICS
10/20/20
Chou R, Dana T, Buckley D, et al. | Ann Intern Med
Aim: To examine the burden of SARS-CoV-2, SARS-CoV-1, and Middle Eastern respiratory syndrome (MERS)-CoV on HCWs and risk factors for infection, using rapid and living review methods.
UPDATED
WHO COLLABORATIVE
10/20/20
Tan E, Song J, Deane AM, et al. | Chest
Aim: To review the evidence on the global point estimate of mortality and risk factors for patients admitted to intensive care units (ICUs) with severe COVID-19.
CLINICAL CHARACTERISTICS
10/20/20
Wassie GT, Azene AG, Bantie GM, et al. | Curr Ther Res Clin Exp
Aim: To estimate the pooled average incubation period of SARS-CoV-2.
CLINICAL CHARACTERISTICS
10/20/20
Chua TH, Xu Z, King NKK | Brain Inj
Aim: To determine the clinical characteristics of neurological manifestations in COVID-19.
CLINICAL CHARACTERISTICS
10/20/20
Kotecha P, Light A, Checcucci E, et al. | Panminerva Med
Aim: To evaluate the data currently available regarding the repurposing of different drugs for Covid-19 treatment. 
UPDATED
CANDIDATE THERAPEUTICS
10/20/20
Sun C, Sun Y, Li X | Am J Emerg Med
Aim: To evaluate the clinical efficacy and safety of CM in the treatment of COVID-19 pneumonia.
CANDIDATE THERAPEUTICS
10/20/20
Hossein H, Ali KM, Hosseini M, et al. | Clin Transl Imaging
Aim: To answer to the question whether CT scan can be used in diagnosis of COVID-19 or not.
DIAGNOSTICS
10/19/20
Fram G, Wang D, Malette K, et al. | Curr Cardiol Rev
Aim: To evaluate the incidence of cardiotoxicity associated with hydroxychloroquine prior to onset of the COVID-19 pandemic.
CANDIDATE THERAPEUTICS
10/19/20
Liu Y, Lu H, Wang W, et al. | Expert Rev Anticancer Ther
Aim: To identify the risk factors for death in patients with cancer and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Mulchandani R, Lyngdoh T, Kakkar AK | Eur J Clin Invest
Aim: To quantify the differences in the circulating levels of major inflammatory and immunological markers between severe and non?severe COVID?19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Ortega KL, Rech BO, El Haje GLC, et al. | J Hosp Infect
Aim: To review the evidence on whether hydrogen peroxide mouthwash has a virucidal effect.
UPDATED
INFECTION CONTROL
10/19/20
Tasar R, Wiegand C, Elsner P | Contact Dermatitis
Aim: To review the evidence on the irritant effects of alcoholic hand rubs.
INFECTION CONTROL
10/19/20
Cantini F, Goletti D, Petrone L, et al. | Drugs
Aim: To assess the clinical impact of different therapies for COVID-19.
CANDIDATE THERAPEUTICS
10/19/20
July J, Pranata R | J Stroke Cerebrovasc Dis
Aim: To evaluate the impact of the coronavirus disease (COVID-19) pandemic on stroke care, including the number of stroke alerts/codes, number of reperfusions, and number of thrombectomies during the pandemic compared to those during the pre-pandemic period.
INFECTION CONTROL
10/19/20
 | CADTH
Aim: To review the various strategies being used to increase the availability of N95 masks.
10/19/20
Abate SM, Mantefardo B, Basu B | Patient Saf Surg
Aim: To provide the global prevalence of perioperative outcomes of patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Chamseddine RS, Wahbeh F, Chervenak F, et al. | J Pregnancy
Aim: To review the evidence on preinatal and obstetric management in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Raschetti R, Vivanti AJ, Vauloup-Fellous C, et al. | Nat Commun
Aim: To clarify the main transmission route, clinical features and outcomes of neonatal SARS-CoV-2 infections
UPDATED
CLINICAL CHARACTERISTICS
10/19/20
Ramaraj P, Super JT, Doyle R, et al. | BMJ Open
Aim: To review the evidence behind UK Government PPE guidance on surgical masks versus respirators for SARS-CoV-2 protection.
UPDATED
INFECTION CONTROL
10/19/20
Pluddemann A, Aronson JK | CEBM
Aim: To review the evidence on the role of T cells and antibodies in immunity to COVID-19 infection.
10/16/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on factors that may help protect Indigenous peoples and communities in Canada and internationally from the COVID-19 pandemic and its impacts.
10/16/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on risk factors are associated with COVID-19 outbreaks and mortality in LTC facilities and what strategies mitigate risk.
10/16/20
Bhatia R, Pedapati R, Komakula S, et al. | J Stroke
Aim: To report the characteristics of stroke in patients with COVID-19.
CLINICAL CHARACTERISTICS
10/15/20
Gonzalez-Rubio J, Navarro-Lopez C, Lopez-Najera E, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the epidemiologic relationship between smoking and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/15/20
Apostolopoulou A, Garrigos ZE, Vijayvargiya P, et al. | Diagnostics
Aim: To investigate the epidemiology, pathogenesis, risk factors, clinical manifestations, diagnosis, treatment and prognosis of COVID-19 associated pulmonary aspergillosis (CAPA).
CLINICAL CHARACTERISTICS
10/15/20
 | NSW Health COVID-19 Critical Intelligence Unit
10/15/20
Akiyama S, Hamdeh S, Micic D, et al. | Ann Rheum Dis
Aim: To assess the prevalence and clinical outcomes of COVID-19 in autoimmune diseases.
CLINICAL CHARACTERISTICS
10/15/20
Chu IY, Alam P, Larson H, et al. | J Travel Med
Aim: To identify: 1) the social consequences of mass quarantine—community-wide movement restrictions—during previous and current infectious disease outbreaks, and 2) recommended strategies to mitigate the negative social implications of COVID-19 lockdowns. 
UPDATED
MENTAL HEALTH
10/15/20
Walsh KA, Spillane S, Comber L, et al. | J Infect
Aim: To summarise the evidence on the duration of infectiousness of individuals in whom SARS-CoV-2 ribonucleic acid is detected.
CLINICAL CHARACTERISTICS
10/14/20
Dehaghi BF, Ghodrati-Torbati A, Teimori G, et al. | Invest Educ Enferm
Aim: To assess the effectiveness of face masks against the novel coronavirus. 
INFECTION CONTROL
10/14/20
Pang KW, Chee J, Subramaniam S, Ng CL | Curr Allergy Asthma Rep
Aim: To quantify the clinical utility of identifying OD in the diagnosis of COVID-19 and determine an estimate of the frequency of OD amongst these patients.
CLINICAL CHARACTERISTICS
10/14/20
Fung HF, Martinez L, Alarid-Escudero F, et al. | Clin Infect Dis
Aim: To review the evidence on the transmission of SARS-CoV-2 within households.
INFECTION CONTROL
10/13/20
Bansal A, Singh AD, Jain V, et al. | Heart Lung
Aim: To determine if D-dimers are elevated in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who have adverse clinical outcomes including all-cause mortality, intensive care unit (ICU) admission or acute respiratory distress syndrome (ARDS).
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Jackson T, Deibert D, Wyatt G, et al. | BMJ Open Respir Res
Aim: To review how official guidance documents and academic publications have classified procedures in terms of whether or not they are aerosol-generating. 
INFECTION CONTROL
10/13/20
Pormohammad A, Ghorbani S, Khatami A, et al. | Rev Med Virol
Aim: To compare clinical symptoms, laboratory findings, radiographic signs and outcomes of COVID?19 and influenza to identify unique features.
CLINICAL CHARACTERISTICS
10/13/20
Chai KL, Valk SJ, Piechotta V, et al. | Cochrane Database Syst Rev
Aim: To assess whether convalescent plasma or hyperimmune immunoglobulin transfusion is effective and safe in the treatment of people with COVID?19.
UPDATED
CANDIDATE THERAPEUTICS
10/13/20
Banakar M, Lankarani KB, Jafarpour D, et al. | BMC Oral Health
Aim: To examine the risk of the transmission of the COVID–19 during dental treatments and provides pathways and protective protocols to minimize them, bearing in mind the long-term necessity of actions and realistic, practical measures.
UPDATED
INFECTION CONTROL
10/13/20
Singh H, Kaur H, Singh K, et al. | Adv Wound Care
Aim: To review the evidence on cutaneous manifestations reported in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/13/20
Aggarwal N, Garg M, Dwarakanathan V, et al. | J Travel Med
Aim: To review the evidence on the diagnostic accuracy of infrared thermal screening via handheld non-contact infrared thermometers and thermal scanners.
DIAGNOSTICS
10/13/20
Roshandel R, Nateqi M, Lak R, et al. | Cell Mol Biol
Aim: To review the evidence on the diagnostic and methodological evaluation of urinary shedding of SARS-CoV-2.
UPDATED
DIAGNOSTICS
10/13/20
Kashour ZT, Riaz M, Garbati M, et al. | J Antimicrob Chemother
Aim: To systematically evaluate the effect of CQ and HCQ with or without azithromycin (AZ) on outcomes of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/13/20
Prodromos C, Rumschlag T | New Microbes New Infect
Aim: To review the efficacy of HCQ against COVID-19.
CANDIDATE THERAPEUTICS
10/13/20
Sathian B, Asim M, Banerjee I, et al. | Nepal J Epidemiol
Aim: To assess the impact of the COVID-19 pandemic on the conduction of clinical trials and research.
INFECTION CONTROL
10/13/20
Sajid MI, Awais S, Salar K, et, al. | Biomedica
Aim: To evaluate the pathogenesis, risk factors, diagnosis and management strategies in pregnant women suspected or confirmed with COVID-19 infection.
CLINICAL CHARACTERISTICS
10/13/20
Han SM, Greenfield G, Majeed A, et al. | J Med Internet Res
Aim: To summarize evidence on the impact of remote consultation in primary care on antibiotic prescribing.
INFECTION CONTROL
10/13/20
Tamuzi JL, Ayele BT, Shumba CS, et al. | BMC Infect Dis
Aim: To review different studies on SARS-CoV, MERS-CoV or COVID-19 associated with HIV/TB co-infection or only TB and to understand the interactions between HIV, TB and COVID-19 and its implications on the burden of the COVID-19 among HIV/TB co-infected or TB patients, screening algorithm and clinical management.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Malaty M, Kayes T, Amarasekera AT, et al. | Eur J Clin Invest
Aim: To examine the current incidence and available treatment for arrhythmias in hospitalized patients with SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Gidari A, Nofri M, Saccarelli L, et al. | Eur J Clin Microbiol Infect Dis
Aim: To review the evidence on the recurrence of coronavirus disease 2019.
CLINICAL CHARACTERISTICS
10/13/20
Hariri LP, North CM, Shih AR, et al. | Chest
Aim: To review the evidence on the lung histopathology described in COVID-19 compared to SARS and H1N1 influenza.
CLINICAL CHARACTERISTICS
10/13/20
Nopp S, Moik F, Jilma B, et al. | Res Pract Thromb Haemost
Aim: To evaluate available data and estimating the prevalence of VTE in COVID?19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Singh S, Desai R, Gandhi Z, et al. | SN Compr Clin Med
Aim: To identify COVID-19-associated TTS case reports and evaluate patient-level demographics, clinical attributes, and outcomes. 
CLINICAL CHARACTERISTICS
10/13/20
Elsayed S, Reddy M, Murthy PM, et al. | Cureus
Aim: To identify the trends of COVID-19 relapse, the effects of co-morbidities on it, and associated mortality rates.
UPDATED
CLINICAL CHARACTERISTICS
10/13/20
Koh WC, Naing L, Chaw L, et al. | PLoS One
Aim:  To estimate the secondary attack rate (SAR) in various settings and to examine whether household transmission differed by symptom status of index case, adult and children (< 18 years old), and relationship to index case.
INFECTION CONTROL
10/10/20
Yokoyama Y, Aikawa T, Takagi H, et al. | J Med Virol
Aim: To investigate the effect of ACEI and ARB on mortality and susceptibility to COVID-19.
CANDIDATE THERAPEUTICS
10/9/20
Li Y, Li J, Zhang Y, et al. | Chin J Integr Med
Aim: To systematically review the clinical practice guidelines for the treatment of coronavirus disease 2019 (COVID-19) patients with Chinese herbal medicine (CHM), summarize their recommendations and evaluate their qualities.
CANDIDATE THERAPEUTICS
10/9/20
Toomey E, Conway Y, Burton C, et al. | Infect Control Hosp Epidemiol
Aim: To review the evidence on the extended use or re-use of single-use respirators and surgical masks by frontline healthcare workers.
INFECTION CONTROL
10/9/20
Abate BB, Kassie AM, Kassaw MW, et al. | BMJ Open
Aim: To assess the sex difference in the prevalence of COVID-19 confirmed cases.
CLINICAL CHARACTERISTICS
10/8/20
Maiese A, Manetti AC, La Russa R, et al. | Forensic Sci Med Pathol
Aim: To collect the currently available pathological data on COVID-19 and review the international literature on the postmortem findings of patients with COVID-19.
CLINICAL CHARACTERISTICS
10/8/20
Gianola S, Jesus TS, Bargeri S, et al. | PLoS One
Aim: To take a snapshot of the amount of scientific development devoted to COVID-19 and gain an idea of the current status of global research. 
10/8/20
Quesada JA, López-Pineda A, Gil-Guillén VF, et al. | Rev Clin Esp
Aim: To provide a more accurate estimate of the incubation period of COVID-19.
CLINICAL CHARACTERISTICS
10/8/20
Ehaideb SN, Abdullah ML, Abuyssin B, et al. | Crit Care
Aim: To assess whether the newly created models reproduce the full spectrum of human COVID-19.
10/8/20
Oliveira CB, Lima CAB, Vajgel G, et al. | J Clin Pathol
Aim: To describe the incidence of AKI, need for renal replacement therapy (RRT) and mortality among patients with COVID-19-associated AKI.
CLINICAL CHARACTERISTICS
10/8/20
Henssler J, Stock F, van Bohemen J, et al. | Eur Arch Psychiatry Clin Neurosci
Aim: To assess the psychological effects in both quarantined and isolated persons compared to non-quarantined and non-isolated persons. 
UPDATED
MENTAL HEALTH
10/8/20
Choi GJ, Kim HM, Kang H, et al. | J Lipid Atheroscler
Aim: To analyze the available knowledge about the potential association between dyslipidemia and the severity of coronavirus disease 2019 (COVID-19) as reported in previous published systematic reviews.
UPDATED
CLINICAL CHARACTERISTICS
10/7/20
Leochico CFD, Espiritu AI, Ignacio SD, et al. | Front Neurol
Aim: To determine the challenges faced by telerehabilitation in the Philippines.
INFECTION CONTROL
10/7/20
Miller L, Bhattacharyya R, Miller AL | Medicine
Aim: To determine the mortality rate of hospitalized patients with Covid-19 in China and to identify factors that may potentially influence this rate.
CLINICAL CHARACTERISTICS
10/7/20
 | NSW Health COVID-19 Critical Intelligence Unit
10/7/20
Ferner RE, Aronson JK | Oxford COVID-19 Evidence Service
10/7/20
Setiati S, Harimurti K, Safitri ED, et al | Acta Med Indones
Aim: To systematically review all relevant studies related to the risk factors and laboratory test results associated with severe illness and mortality in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/7/20
Betancourt JA, Rosenberg MA, Zevallos A, et al. | Healthcare
Aim: To review the evidence on the impact of the COVID-19 pandemic on the provision of care through telemedicine across unique health service lines that include dermatology, oncology, obstetrics/gynecology, and mental health.
INFECTION CONTROL
10/7/20
Magill E, Siegel Z, Pike KM | Psychiatr Serv
Aim: To review the evidence on the anticipated mental health sequelae for frontline health workers and best practices to address those mental health needs.
MENTAL HEALTH
10/7/20
Luo L, Fu M, Li Y, et al. | Clin Cardiol
Aim: To assess the association between underlying comorbidities and acute cardiac injury and the severity or the prognosis in COVID?19 patients.
CLINICAL CHARACTERISTICS
10/7/20
 | NSW Health COVID-19 Critical Intelligence Unit
10/6/20
Yekeduz E, Utkan G, Urun Y | Eur J Cancer
Aim: To evaluate cancer treatment’s effect on the severity of COVID-19.
CLINICAL CHARACTERISTICS
10/6/20
Mandal A, Nandi S, Chhebbi M, et al. | Indian J Otolaryngol Head Neck Surg
Aim: To review the current guidelines and safety measures to be followed during tracheostomy in COVID-19 infected patients.
CLINICAL CHARACTERISTICS
10/6/20
Kamel AM, Sobhy M, Magdy N, et al. | Rev Med Virol
Aim: To investigate the association between AC and outcomes in hospitalized Covid?19 patients.
CLINICAL CHARACTERISTICS
10/6/20
Tu TM, Goh C, Tan YK, et al. | J Stroke Cerebrovasc Dis
Aim: To perform a systematic review of known cases of concomitant COVID-19 infection and CVT in the current literature.
CLINICAL CHARACTERISTICS
10/6/20
Olorunsaiye CZ, Yusuf KK, Reinhart K, et al. | Int J MCH AIDS
Aim: To review the evidence on the immunization landscape since the COVID-19 pandemic.
INFECTION CONTROL
10/6/20
Cheng W, Li Y, Cui L, et al. | Front Pharmacol
Aim: To evaluate the efficacy and safety of corticosteroid therapy in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/6/20
Sharma SK, Mishra M, Mudgal SK | J Educ Health Promot
Aim: To update the available most recent evidences on efficacy of cloth face masks in prevention of viral infection transmission.
10/6/20
Cheong KX | Curr Ophthalmol Rep
Aim: To summarise and discuss the current literature regarding ocular involvement of SARS-CoV-2 in COVID-19.
CLINICAL CHARACTERISTICS
10/6/20
Jena A, Singh AK, Kumar-M P, et al. | Dig Liver Dis
Aim: To identify the frequency and reasons for the disruption of care for IBD patients and attempted to identify regional differences in patterns of adherence to IBD therapies.
10/5/20
Meyerowitz-Katz G, Merone L | Int J Infect Dis
Aim: To review the evidence on infection-fatality rates for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
10/5/20
Noorimotlagh Z, Mirzaee SA, Jaafarzadeh N, et al. | Environ Sci Pollut Res Int
Aim: To collect all available studies concerning inactivation methods, environmental survival, and control and prevention strategies related to SARS-CoV-2. 
INFECTION CONTROL
10/5/20
Tlayjeh H, Mhish O, Enani M, et al. | J Infect Public Health
Aim: To systematically review the literature about the association between systemic corticosteroid therapy (CST) and outcomes of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/5/20
Moutchia J, Pokharel P, Kerri A, et al. | PLoS One
Aim: To assess clinical laboratory parameters which may serve as markers or predictors of severe or critical COVID-19.
UPDATED
DIAGNOSTICS
10/5/20
Soeroto AY, Soetedjo NN, Purwiga A, et al. | Diabetes Metab Syndr
Aim: To evaluate the association between obesity and composite poor outcome in coronavirus disease 2019 (COVID-19) patients.
UPDATED
CLINICAL CHARACTERISTICS
10/5/20
Chaudhry H, Nadeem S, Mundi R | Clin Orthop Relat Res
Aim: To review the evidence on patient and surgeon satisfaction with the use of telemedicine, differences in outcomes compared to in-person visits and the difference in time commitment.
INFECTION CONTROL
10/5/20
Huang Y, Yao L, Huang Y, et al. | Metabolism
Aim: To review the evidence on the effects of obesity with the risk of severe disease among patients with COVID-19.
CLINICAL CHARACTERISTICS
10/5/20
Wilt TJ, Kaka AS, MacDonald R, et al. | Ann Intern Med
Aim: To evaluate the effectiveness and harms of remdesivir for COVID-19.
CANDIDATE THERAPEUTICS
10/5/20
Simons D, Shahab L, Brown J, et al. | Addiction
Aim: To estimate the association of smoking status with rates of i) infection, ii) hospitalisation, iii) disease severity, and iv) mortality from SARS?CoV?2/COVID?19 disease.
CLINICAL CHARACTERISTICS
10/5/20
Jarrom D, Elston L, Washington J, et al. | BMJ Evid Based Med
Aim: To identify evidence on: (1) the clinical effectiveness of tests that detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) to inform COVID?19 diagnosis? and (2) the clinical effectiveness of tests that detect the presence of antibodies to the SARS?CoV?2 virus to inform COVID?19 diagnosis.
UPDATED
DIAGNOSTICS
10/5/20
Deng J, Zhou F, Hou W, et al. | Ann N Y Acad Sci
Aim: To assess the prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients.
CLINICAL CHARACTERISTICS
10/2/20
Simoni P, Bazzocchi A, Boitsios G, et al. | J Med Imaging Radiat Oncol
Aim: To describe the chest CT features reported in children with confirmed COVID?19 infection.
CLINICAL CHARACTERISTICS
10/2/20
Jahangir M, Nawaz M, Nanjiani D, et al. | Hong Kong Med J
Aim: To review the characteristics and presentation of COVID-19 among children and describe any subtle characteristics that may strengthen the clinical suspicion of infection and prompt further testing. 
CLINICAL CHARACTERISTICS
10/2/20
Carrillo-Larco RM, Altez-Rodriguez C, Ravaglia S, et al. | Wellcome Open Res
Aim: To understand the characteristics of patients with COVID-19 and GBS, and to identify potential patterns.
UPDATED
CLINICAL CHARACTERISTICS
10/2/20
Mhango M, Dzobo M, Chitungo I, et al. | Saf Health Work
Aim: To map available evidence on Covid-19 risk factors among HWs to guide future research and policy.
CLINICAL CHARACTERISTICS
10/2/20
Rostami M, Mansouritorghabeh H | Expert Rev Hematol
Aim: To analyze the levels of D-dimer in patients with COVID-19.
CLINICAL CHARACTERISTICS
10/2/20
Oliviera Silva DF, Cunha Lima SC, Mauricio Sena-Evangelista KC, et al. | Nutrients
Aim: To identify the screening instruments that can be used to assess nutritional risk in older adults with COVID-19, and to clarify their measurement properties.
UPDATED
CLINICAL CHARACTERISTICS
10/2/20
Flumignan RLG, de Sa Tinoco JD, Pascoal PIF, et al. | Cochrane Database Syst Rev
Aim: To assess the effects of prophylactic anticoagulants versus active comparator, placebo or no intervention, on mortality and the need for respiratory support in people hospitalised with COVID?19.
UPDATED
CANDIDATE THERAPEUTICS
10/2/20
Yang S, Li A, Eshaghpour A, et al. | BMJ Evid Based Med
Aim: To review the trends and quality of evidence in early SARS-CoV-2 publications.
10/2/20
Leaune E, Samuel M, Oh H, et al. | Prev Med
Aim: To systematically review the evidence on the association between EVDOs and suicidal behaviors and/or ideation.
MENTAL HEALTH
10/2/20
Salari N, Khazaie H, Hosseinian-Far A, et al. | Global Health
Aim: To investigate the prevalence of sleep disturbances in hospital nurses and physicians facing the COVID-19 patients.
MENTAL HEALTH
10/2/20
Antikchi MH, Neamatzadeh H, Ghelmani Y, et al. | J Gastrointest Cancer
Aim: To estimate the risk and prevalence of COVID-19 infection in CRC patients using all available data.
INFECTION CONTROL
10/2/20
Li WT, Ma J, Shende N, et al. | BMC Med Inform Decis Mak
Aim: To investigate correlations between clinical variables, cluster COVID-19 patients into subtypes, and generate a computational classification model for discriminating between COVID-19 patients and influenza patients based on clinical variables alone.
DIAGNOSTICS
9/29/20
Hussain N, Chung E, Heyl JJ, et al. | Cureus
Aim: To assess the effects of HCQ on patients with COVID-19.
CLINICAL CHARACTERISTICS
9/29/20
Uygun-Can B, Acar-Bolat B | Biomed Res Int
Aim: To summarize reliable medical evidence by the meta-analysis of all published retrospective studies that examined data based on the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by clinical symptoms, molecular (RT-PCR) diagnosis, and characteristic CT imaging features in pregnant women.
CLINICAL CHARACTERISTICS
9/29/20
Oliveira LV, Silva C, Lopes LP, et al. | Rev Assoc Med Bras
Aim: To review the current scientific evidence of vertical transmission related to coronavirus disease 2019 (COVID-19).
9/29/20
Bhattacharjee S, Banerjee M | SN Compr Clin Med
Aim: To analyze the clinical profile and outcomes in a total of 45 cases of new-onset ITP in COVID-19 patients described in literature until date.
9/29/20
Morone G, Palomba A, Iosa M, et al.  | Front Med
Aim: To correlate the presence and the relevant temporal patterns of SARS-CoV-2 viral RNA in biological specimens (stool, urine, blood, and tears) of the transmission with clinical/epidemiological features in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
9/29/20
Abuelgasim E, Dona ACM, Sondh RS, et al. | Dermatol Ther
Aim: To review the current literature on urticaria in COVID-19 patients and to provide insight into urticarial pathogenesis and management in such patients.
9/29/20
de Araujo LA, Veloso CF, de Campos Souza M, et al. | J Pediatr
Aim: To examine the impact of epidemics or social restriction on mental and developmental health in parents and children/adolescents.
MENTAL HEALTH
9/28/20
Sheleme T, Bekele F, Ayela T | Infect Dis
Aim: To summarize clinical presentations of this newly emerging coronavirus disease.
9/28/20
Shrestha DB, Pudhathoki P, Khadka S, et al. | Virol J
Aim: To review the efficacy and safety of favipiravir triphosphate as a treatment for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/28/20
Malik P, Patel U, Patel K, et al. | J Med Virol
Aim: To assess the association of obesity and outcomes in COVID?19 hospitalized patients.
9/28/20
Rios P, Radhakrishnan A, Williams C, et al. | Syst Rev
Aim: to examine the current guidelines for infection prevention and control (IPAC) of coronavirus disease-19 (COVID-19) or other coronaviruses in adults 60 years or older living in long-term care facilities (LTCF).
UPDATED
INFECTION CONTROL
9/28/20
 | Public Health Agency of Canada
Aim: Not provided
9/28/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the potential for COVID-19 re-infection, including new transmission after recovery.
9/28/20
de Assis GG, Murawksa-Cialowicz E, Cieszczyk P, et wl. | Front Neurol
Aim: To review the evidence on the implications and mechanisms of infections by respiratory CoVs.
9/28/20
Viner RM, Mytton OT, Bonell C, et al. | JAMA Pediatr
Aim: To review the evidence on the susceptibility to and transmission of SARS-CoV-2 by children and adolescents compared with adults.
UPDATED
INFECTION CONTROL
9/25/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence that CPR is aerosol generating and current advice for CPR in patients with suspected or confirmed COVID-19.
9/25/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the impact of COVID-19 and related public health measures on household food security.
9/25/20
Singh B, Gornet M, Sims H, et al. | Am J Reprod Immunol
Aim: To analyze the available evidence on SARS-CoV-2 infection, early pregnancy, and reproductive tissues.
CLINICAL CHARACTERISTICS
9/24/20
Bennett S, Tafuro J, Mayer J, et al. | Int J Clin Pract
Aim: To identify the symptoms, comorbidities present, radiological features and outcomes for adults testing positive for COVID?19 admitted to hospital.
CLINICAL CHARACTERISTICS
9/24/20
Lim MA, Pranata R | J Clin Orthop Trauma
Aim: To evaluate the prevalence of coronavirus disease 2019 (COVID-19) and its impact on mortality in patients with hip fracture.
UPDATED
CLINICAL CHARACTERISTICS
9/24/20
Malgie J, Schoones JW, Pijls BG | Clin Infect Dis
Aim: To review the evidence on the use of IL-6 (receptor) antagonist therapy in reducing mortality in COVID-19 patients.
CANDIDATE THERAPEUTICS
9/24/20
Wang Y, Chen J, Chen W, et al. | Int Arch Allergy Immunol
Aim: To explore the literature and collate data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma.
CLINICAL CHARACTERISTICS
9/24/20
Wang M, Wu T, Zuo Z, et al. | BMJ Support Palliat Care
Aim: To summarize the efficacy and safety of antiviral agents currently in use for COVID-19 treatment.
UPDATED
CANDIDATE THERAPEUTICS
9/24/20
Berling I, King JD, Shepherd G, et al. | J Am Soc Nephrol
Aim: To determine the effect of and indications for extracorporeal treatments in cases of poisoning with chloroquine, hydroxychloroquine, and quinine.
9/24/20
Murchu EO, Byrne P, Walsh KA, et al. | Rev Med Virol
Aim: To summarize the evidence on the immune response and reinfection rate following SARS?CoV?2 infection. 
CLINICAL CHARACTERISTICS
9/24/20
Roncon L, Zuin M, Barco S, et al. | Eur J Intern Med
Aim: To perform a systematic review and meta-analysis of the in-hospital incidence of acute PE among COVID-19 patients based on studies published within four months of COVID-19 outbreak.
CLINICAL CHARACTERISTICS
9/24/20
Goncalves LF, Gonzales AI, Patatt FSA, et al. | Rev Assoc Med Bras
Aim: To present scientific evidence evaluating the association of Kawasaki Disease (DK) and COVID-19 in children.
CLINICAL CHARACTERISTICS
9/24/20
Buitrago-Garcia D, Egli-Gany D, Counotte MJ, et al. | PLoS Med
Aim: To review the evidence on asymptomatic SARS-CoV-2 transmission.
CLINICAL CHARACTERISTICS
9/24/20
Nogueira SAR, de Oliveira SCS, de Carvalho AFM, et al. | Rev Assoc Med Bras
Aim: To present a review of renal changes in patients with COVID-19.
CLINICAL CHARACTERISTICS
9/24/20
Ibekew TS, Fasunla AJ, Orimadegun AE | OTO Open
Aim: To estimate prevalence of smell and taste loss among COVID-19 patients.
CLINICAL CHARACTERISTICS
9/24/20
Gulsen A, Yigitbas BA, Uslu B, et al. | Pulm Med
Aim: To determine the relationship between smoking and clinical COVID-19 severity via a systematic meta-analysis approach.
UPDATED
CLINICAL CHARACTERISTICS
9/24/20
Cabarkapa S, Nadjidai SE, Murgier J, et al. | Brain Behav Immun Health
Aim: To explore the main findings from the literature examining the psychological impact on HCWs in times of severe epidemics, and to identify strategies to address this.
MENTAL HEALTH
9/23/20
O'Reilly A, Tibbs M, Booth A, et al. | Ir J Psychol Med
Aim: To summarise existing evidence on the potential impact of a pandemic on the mental health of 12-25-year-olds.
UPDATED
MENTAL HEALTH
9/23/20
Navarro P | Newfoundland and Laborador Centre for Applied Health Research
Aim: To review the evidence on the medium-term and long-term health impacts of COVID-19 on infection survivors.
9/22/20
Li X, Xu Z, Wang T, et al. | Clin Epidemiol Glob Health
Aim: To identify clinical characteristics of severe patients with COVID-19.
CLINICAL CHARACTERISTICS
9/22/20
van Boekel L, Stoop A, Luijkx KG | Tijdschr Gerontol Geriatr
Aim: To understand what we can learn from previous crises or disasters worldwide to optimize the care for older adults in long term care facilities during the outbreak of COVID-19. 
9/22/20
 | CADTH
Aim: To review evidence related to airflow transmission of SARS-CoV-2 and the risk associated with the use of heating, ventilation, and air conditioning (HVAC) systems.
9/22/20
Melo-Oliveira ME, Sa-Caputo D, Bachur JA, et al. | Expert Rev Respir Med
Aim: To summarize effects of the COVID-19 in the QoL of the studied populations.
CLINICAL CHARACTERISTICS
9/22/20
Boyce L, Nicolaides M, Hanrahan JG, et al. | J Plast Reconstr Aesthet Surg
Aim:  To identify all published literature on plastic surgery and COVID-19, in an effort to summarise the evidence for future reference.
INFECTION CONTROL
9/21/20
Huang AT, Garcia Carreras B, Hitchings MDT, et al. | Nat Commun
Aim: To review the scientific literature on antibody immunity to coronaviruses, including SARS-CoV-2 as well as the related SARS-CoV, MERS-CoV and endemic human coronaviruses (HCoVs). 
UPDATED
CLINICAL CHARACTERISTICS
9/21/20
Marinaki S, Tsiakas S, Korogiannou M, et al. | J Clin Med
Aim: To analyze the data of studies reporting on adult KTx recipients with confirmed COVID-19.
CLINICAL CHARACTERISTICS
9/21/20
Lo KB, Bhargav R, Salacup G, et al. | Expert Rev Cardiovasc Ther
Aim: To investigate the impact of ACEI/ARB on COVID-19 associated disease severity and mortality through a systematic review and meta-analysis of existing literature.
CLINICAL CHARACTERISTICS
9/21/20
Moosavi MS, Aminishakib P, Ansari M | J Oral Microbiol
Aim: To review the evidence on the effects of different types of mouthwashes to reduce viral load.
INFECTION CONTROL
9/21/20
Chen J, See KC | J Med Internet Res
Aim: To review AI applications for COVID-19.
DIAGNOSTICS
9/21/20
Yoon S, Li H, Lee KH, et al. | Medicina
Aim: To compare characteristics among: (1) asymptomatic versus symptomatic and (2) less than 10 versus greater or equal to 10 years old pediatric COVID-19 patients. 
CLINICAL CHARACTERISTICS
9/21/20
Cabrera MA, Karamsetty L, Simpson SA | Psychosomatics
Aim: To provide a critical synthesis of the scientific literature on the pandemic's implications for psychiatric practice.
INFECTION CONTROL
9/21/20
Trevisanuto D, Cavallin F, Cavicchiolo ME, et al. | Arch Dis Child Fetal Neonatal Ed
Aim: To summarise currently reported neonatal cases of SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
9/21/20
Singh S, Fong HK, Mercedes BR, et al. | Resuscitation
Aim: To review the evidence on the change in out-of-hospital cardiac arrest indicence and mortality during the COVID-19 outbreak in various countries.
9/21/20
Mecenas P, da Rose Moreira Bastos RT, Vallinoto ACR, et al. | PLoS One
Aim: To describe current knowledge about the emergence and replicability of the virus and its connection with different weather factors such as temperature and relative humidity.
UPDATED
INFECTION CONTROL
9/21/20
Acheampong DO, Barffour IK, Boye A, et al. | Biomed Pharmacother
Aim: To review the evidence on the possible biological reasons which underpin the differences observed in the outcome of COVID-19 among males and females.
CLINICAL CHARACTERISTICS
9/21/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the effect of the COVID-19 pandemic on opioid and substance use and related harms.
9/21/20
Luigi B, Francesco B, Giovanni B, et al. | Oral Dis
Aim: To review the evidence on surfaces decontamination and protection masks for SARS-CoV-2 in dental practice.
INFECTION CONTROL
9/21/20
Yang T, Chou C, Yang Y, et al. | J Chin Med Assoc
Aim: To address not only the benefits and safety issues of HCQ in COVID-19 treatment and to evaluate the effects in combination with the use of macrolide, especially AZI in therapy.
CANDIDATE THERAPEUTICS
9/21/20
Khalaj K, Figueira RL, Antounians L, et al. | J Extracell Vesicles
Aim: To analyse whether EV-based therapies could be effective in treating severe pulmonary conditions that affect COVID-19 patients and to understand their relevance for an eventual therapeutic application to human patients. 
CANDIDATE THERAPEUTICS
9/21/20
Hamedani S, Farshidfar N, Ziaei A, et al. | European Oral Research
Aim: To review relevant current evidence in literature that has addressed the role of saliva and the threats that may be inherent in transmission of the disease during dental procedures.
INFECTION CONTROL
9/18/20
WHO REACT Working Group | JAMA
Aim: To estimate the association between administration of corticosteroids compared with usual care or placebo and 28-day all-cause mortality.
WHO COLLABORATIVE
CANDIDATE THERAPEUTICS
9/18/20
Malik P, Patel U, Mehta D, et al. | BMJ Evid Based Med
Aim: To evaluate association between biomarkers and outcomes in COVID-19 hospitalised patients.
CLINICAL CHARACTERISTICS
9/18/20
Zahra SA, Iddawela S, Pillai K, et al. | Brain Behav
Aim: To investigate the diagnostic value of symptoms of anosmia and dysgeusia for COVID?19.
DIAGNOSTICS
9/18/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
Aim: To review the evidence on the effectiveness of reducing prison populations to reduce the spread of COVID-19.
9/18/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on whether domestic animals can become infected with and transmit COVID-19.
9/18/20
Pranata R, Huang I, Lim MA, et al. | J Stroke Cerebrovasc Dis
Aim: To evaluate the latest evidence on the association between cerebrovascular, and cardiovascular diseases and poor outcome in patients with Coronavirus Disease 2019 (COVID-19) pneumonia.
CLINICAL CHARACTERISTICS
9/18/20
Mojtabavi H, Saghazadeh A, Rezaei N | Eur Cytokine Netw
Aim: To investigate whether the circulating levels of IL-6 is a reliable indicator of disease severity among patients affected with COVID-19.
DIAGNOSTICS
9/18/20
Lagzian M, Dadkhah M, Mehraeen A | Eur J Clin Invest
Aim: To recognize the challenges policymakers have typically experienced during pandemic diseases, including Covid-19, and, accordingly, new information technology capabilities to encounter with them.
9/18/20
Orru G, Conversano C, Malloggi E, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the neurological complications of possible neuroinvasion related to SARS-CoV-2.
CLINICAL CHARACTERISTICS
9/18/20
Paknahad Z, Moravejolahkami AR | Endocr Metab Immune Disord Drug Targets
Aim: To review the evidence on the effects of probiotics on incidence, severity, duration, and other clinical manifestations of viral infections especially SARS-CoV-2-induced.
CANDIDATE THERAPEUTICS
9/18/20
Campbell CM, Guha A, Haque T, et al. | J Clin Med
Aim: To characterize the current state of immunotherapy trials in COVID-19, and focuses on associated cardiotoxicities, given the importance of pharmacovigilance.
CANDIDATE THERAPEUTICS
9/18/20
Leung T, Chan A, Chan EW, et al. | Emerg Microbes Infect
Aim: To summarize the current evidence on the short-term adverse health outcomes and assess the risk of potential long-term adverse outcomes of COVID-19. 
CLINICAL CHARACTERISTICS
9/18/20
Fridman S, Bullrich MB, Jimenez-Ruiz A, et al. | Neurology
Aim: To investigate the hypothesis that strokes occurring in patients with COVID-19 have distinctive features.
CLINICAL CHARACTERISTICS
9/18/20
Rajan MB, Kumar P, Bhardwaj A | Int J Dermatol
Aim: To estimate the prevalence of cutaneous manifestations in COVID?19 patients.
CLINICAL CHARACTERISTICS
9/17/20
Pastick KA, Nicol MR, Smyth E, et al. | Open Forum Infect Dis
Aim: To review the available evidence on COVID-19 cases during pregnancy and summarize clinical trials enrolling this population.
CLINICAL CHARACTERISTICS
9/17/20
McLane P | Alberta Health Services
Aim: To review the evidence on the factors impacting attitudes toward or adherence to COVID-19 public health guidelines and interventions to create more positive attitudes towards following guidelines.
9/17/20
Macaluso FS, Orlando A | Dig Liver Dis
Aim: To review the evidence on published COVID-19 cases ocurring in patients with IBD.
CLINICAL CHARACTERISTICS
9/17/20
Dambha-Miller H, Albasri A, Hodgson S, et al. | BMJ Open
Aim: To review evidence on routinely prescribed drugs in the UK that could upregulate or downregulate ACE2 and potentially affect COVID-19 disease.
UPDATED
CANDIDATE THERAPEUTICS
9/17/20
Chang T, Chou C, Chang L | Obes Rev
Aim: To examine the effects of body mass index (BMI) and obesity (BMI ? 30 kg/m2) on coronavirus disease 2019 (COVID?19).
CLINICAL CHARACTERISTICS
9/17/20
Juul S, Nielsen N, Feinberg J, et al. | PLoS Med
Aim: To compare the effects of all treatment interventions for participants in all age groups with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
9/17/20
Lasheras I, Gracia-Garcia P, Lipnicki DM, et al. | Int J Environ Res Public Health
Aim: To investigate the prevalence of anxiety in medical students during this pandemic.
MENTAL HEALTH
9/17/20
Wang Y, Ao G, Qi X, et al  | Clin Exp Allergy
Aim: To review the evidence on the association of asthma with risk of severe or fatal COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
9/17/20
Christophers B, Marin BG, Oliva R et al. | Pediatr Res
Aim: To describe the clinical presentation and outcomes of pediatric patients using an individual patient data approach to visualize trends by age.
UPDATED
CLINICAL CHARACTERISTICS
9/16/20
Du Y, Lv Y, Zha W et al. | Metabolism
Aim: To explore the association between BMI and COVID-19 severity and mortality
CLINICAL CHARACTERISTICS
9/16/20
 | CADTH
Aim: To provide information on ongoing randomized controlled trials of drugs being investigated to treat or prevent COVID-19.
9/15/20
da Silva ML, Rocha RSB, Buheji M, et al. | J Health Psychol
Aim: To assess the prevalence of generalized anxiety disorder (GAD) in pandemic survivors and the general population.
MENTAL HEALTH
9/15/20
Cheruiyot I, Henry B, Lippi G, et al. | Acta Biomed
Aim: To assess whether AKI may be associated with worse prognosis and increased mortality in COVID-19 patients
UPDATED
9/15/20
Peres KC, Riera R, Martimbianco ALC, et al. | Front Endocrinol
Aim: To investigate a possible association between body weight and prognosis among patients diagnosed with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
9/15/20
Muhammad SZ, Ahmed A, Shahid I, et al. | Infez Med
Aim: To systematically review these studies and to conduct a meta-analysis of their results to provide a well-powered assessment of chest CT findings in patients with COVID-19.
CLINICAL CHARACTERISTICS
9/15/20
Ciuca IM | Risk Manag Healthc Policy
Aim: To describe the current knowledge about coronavirus disease 2019 (COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) in children, from epidemiological, clinical, and laboratory perspectives, including knowledge on the disease course, treatment, and prognosis.
CLINICAL CHARACTERISTICS
9/15/20
Bizzoca ME, Campisi G, Lo Muzio L | Int J Environ Res Public Health
Aim: To illustrate the most accepted models of safety protocols in dentistry and oral medicine, and to propose an easy view of the problem and a comparison (pre- vs post-COVID19) for the most common dental procedures.
INFECTION CONTROL
9/15/20
Fiorillo L, Cervino G, Matarese M, et al. | Int J Environ Res Public Health
Aim: To highlight all the sources currently present in the literature concerning the persistence of the different coronaviruses in the environment as well as in medical and dental settings. 
INFECTION CONTROL
9/15/20
Yamamoto V, Bolanos JF, Fiallos J, et al. | J Alzheimers Dis
Aim: To provide a comprehensive review of SARS-CoV-2-induced disease, its mechanism of infection, diagnostics, therapeutics, and treatment strategies, while also focusing on less attended aspects by previous studies, including nutritional support, psychological, and rehabilitation of the pandemic and its management.
CANDIDATE THERAPEUTICS
9/15/20
Aziz H, Lashkari N, Yoon YC, et al. | Transplant Proc
Aim: To assess currently published literature relating to the management, clinical course and outcomes of SARS-Cov-2 infection in liver, kidney and heart SOT recipients.
CLINICAL CHARACTERISTICS
9/15/20
Roberto KT, Espiritu AI, Fernandez MLL, et al. | Seizure
Aim: To review the EEG findings in patients diagnosed with COVID-19 infection through a systematic review of published articles.
CLINICAL CHARACTERISTICS
9/15/20
 | Health Information and Quality Authority, Ireland
Aim: To review the evidence on the duration of infectiousness in those that test positive for SARS-CoV-2 RNA.
9/15/20
Siepmann T, Sedghi A, Simon E, et al. | Eur J Neurol
Aim: To define the risk of acute stroke in patients with severe and non-severe COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
9/15/20
Zhang A, Leng Y, Zhang Y et al. | Int J Infect Dis
Aim: To figure out whether abnormal coagulation parameters are associated with disease severity and poor prognosis in patients with 2019 Corona Virus Disease (COVID-19)
CLINICAL CHARACTERISTICS
9/15/20
Ahmed M, Advani S, Moreira A, et al. | EClinicalMedicine
Aim: To describe the typical presentation and outcomes of children diagnosed with this hyperinflammatory condition.
UPDATED
CLINICAL CHARACTERISTICS
9/15/20
 | Quebec National Institute of Public Health
Aim: To review the evidence on risk factors for severe infections and potential for transmission in children.
9/15/20
Sharpe H | Alberta Health Services
Aim: To review the evidence on different methods, completion rates, and costs for self-collected samples for SARS-CoV-2 RT-PCR.
9/15/20
Ricco M, Ranzieri S, Peruzzi S, et al. | Acta Biomed
Aim: To conduct a meta-analysis on the sensitivity and specificity of SARS-CoV-2 viral RNA detection through RT-qPCR based on salivary specimens compared to conventional nasopharyngeal swabs.
DIAGNOSTICS
9/15/20
Banerjee I, Robinson J, Kashyap A, et al. | Nepal J Epidemiol
Aim: To assess the impact of COVID-19 on the younger age group in terms of the Global mortality of COVID-19 in comparison to Nepal. 
CLINICAL CHARACTERISTICS
9/15/20
Aronoff SC, Hall A, Del Vecchio MT | J Pediatric Infect Dis Soc
Aim: To provide a detailed clinical description and natural history of MIS-C.
CLINICAL CHARACTERISTICS
9/15/20
Viswanathan M, Kahwati L, Jahn B, et al. | Cochrane Database Syst Rev
Aim: To assess (1) the effectiveness of universal screening for SARS?CoV?2 infection compared with no screening and (2) the accuracy of universal screening in people who have not presented to clinical care for symptoms of COVID?19.
INFECTION CONTROL
9/14/20
Lee JC, Nallani R, Cass L, et al. | Am J Rhinol Allergy
Aim: To synthesize the existing primary literature related to olfactory dysfunction secondary to viral infection, detail the underlying pathophysiological mechanisms, highlight relevance for the current COVID-19 pandemic, and identify high impact areas of future research.
CLINICAL CHARACTERISTICS
9/14/20
Mark EG, Golden WC, Gilmore MM, et al. | J Pediatr
Aim: To summarize and evaluate current reports on community-onset severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in young infants.
CLINICAL CHARACTERISTICS
9/14/20
Jimenez-Ruiz CA, Lopez-Padilla D, Alonso-Arroyo A, et al. | Arch Bronconeumol
Aim: To review the evidence on the association between tobacco use in patients with COVID-19 and negative progression and adverse outcome of the disease.
CLINICAL CHARACTERISTICS
9/14/20
Klein MG, Cheng CJ, Lii E, et al. | Disaster Med Public Health Prep
Aim: To highlight models that project both caseload and hospital capacity requirements over time.
9/14/20
Williams N, Radia T, Harman K, et al. | Eur J Pediatr
Aim: To identify and describe which underlying comorbidities may be associated with severe SARS-CoV-2 disease and death in children.
CLINICAL CHARACTERISTICS
9/14/20
Siemieniuk RAC, Bartoszko JJ, Ge L, et al. | BMJ
Aim: To compare the effects of treatments for coronavirus disease 2019 (covid-19).
UPDATED
CANDIDATE THERAPEUTICS
9/14/20
Aziz M, Haghbin H, Sitta EA, et al. | J Med Virol
Aim: To compare the efficacy of addition of TOC to standard of care (SOC) versus SOC in patients with COVID?19.
CANDIDATE THERAPEUTICS
9/14/20
Di Maria E, Latini A, Borgiani P, et al. | Human Genomics
Aim: To review the evidence on genetic variants of the human host influencing the coronavirus-associated phenotypes (SARS, MERS, and COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
9/14/20
Fernandez R, Lord H, Halcomb E, et al. | Int J Nurs Stud
Aim: To synthesize and present the best available evidence on the experiences of nurses working in acute hospital settings during a pandemic.
9/14/20
Hasan SS, Kow CS, Hadi MA, et al. | Am J Cardiovasc Drugs
Aim: To critically examine the association of RAS inhibitors use with mortality and disease severity in COVID-19.
CANDIDATE THERAPEUTICS
9/14/20
Panda PK, Sharawat IK, Panda P, et al. | J Trop Pediatr
Aim: To review the evidence on the neurological manifestations of COVID-19 in children.
UPDATED
CLINICAL CHARACTERISTICS
9/14/20
Amorim dos Santos J, Normando AGC, Carvalho da Silva RL, et al. | J Dent Res
Aim: To provide a comprehensive up-to-date summary of oral manifestations in patients with COVID-19.
9/14/20
Nino G, Zember J, Sanchez-Jacob R, et al. | Pediatr Pulmonol
Aim: To provide the first comprehensive summary of the findings of published studies thus far describing COVID-19 lung imaging data in the pediatric population.
CLINICAL CHARACTERISTICS
9/14/20
Cozzupoli GM, Savastano MC, Galsini B, et al. | J Ophthalmol
Aim: To review and analyze previous studies conducted on ritonavir administration and retinal impairment in a narrative synthesis. 
CANDIDATE THERAPEUTICS
9/14/20
Nussbaumer-Streit B, Mayr V, Dobrescu AI, et al. | Cochrane Database of Systematic Reviews
Aim: To assess the effects of quarantine (alone or in combination with other measures) of individuals who had contact with confirmed cases of COVID19, who travelled from countries with a declared outbreak, or who live in regions with high transmission of the disease.
UPDATED
WHO COLLABORATIVE
INFECTION CONTROL
9/14/20
Florez-Perdomo WA, Serrato-Vargas SA, Bosque-Varela P, et al. | Clin Neurol Neurosurg
Aim: To evaluate and summarize the level of evidence on past history of stroke in COVID19 patients.
CLINICAL CHARACTERISTICS
9/14/20
Patoulias D, Katsimardou A, Stavropoulos K, et a. | Curr Hypertens Rep
Aim: To evaluate the association between the use of either ACE inhibitors or ARBs and the risk for major clinical endpoints (infection, hospitalization, admission to ICU, death) in adult patients during the COVID-19 pandemic. 
CLINICAL CHARACTERISTICS
9/14/20
Elhabyan A, El Yaacoub S, Sanad E, et al. | Virus Res
Aim: To identify the candidate genes that are likely to aid in explaining severe COVID-19 and provide insights to understand severe COVID-19.
CLINICAL CHARACTERISTICS
9/14/20
Zeng M, Li L, Wu Z | PLoS ONE
Aim: To review the evidence on the clinical efficacy and safety of the traditional Chinese medicine Lianhua Qingwen in the treatment of new coronavirus pneumonia (COVID-19). 
CANDIDATE THERAPEUTICS
9/12/20
Noor FM, Islam MM | J Community Health
Aim: To find the prevalence of mortality among hospitalized COVID-19 infected patients and associated risk factors for death.
CLINICAL CHARACTERISTICS
9/12/20
Hussain N, Yoganathan A, Hewage S, et al. | Expert Rev Anti Infect Ther
Aim: To identify studies pertaining to antivirals, both as sole and combined therapies, in COVID-19 patients and review the clinical outcomes of these treatment methods.
CANDIDATE THERAPEUTICS
9/11/20
Usman AS, Siddiqi TJ, Khan MS, et al. | Am J Cardiol
Aim: To conduct a meta-analysis of all available data on the relationship between renin-angiotensin aldosterone system of inhibitors and COVID-19.
CANDIDATE THERAPEUTICS
9/11/20
Sun M, Xu Y, He H, et al. | Int J Infect Dis
Aim: To explore the effectiveness of treatment and predict the potential effects of CP with COVID-19.
CANDIDATE THERAPEUTICS
9/11/20
Sun Z, Zhang N, Li Y, et al. | Quant Imaging Med Surg
Aim: To analyze the currently available studies documenting radiologic findings and aim to clarify the role of CT imaging in the diagnosis of patients with COVID-19.
DIAGNOSTICS
9/11/20
Brienza N, Puntillo F, Romagnoli S, et al. | Blood Purif
Aim: To clarify the incidence and the impact of COVID-19-related AKI on mortality.
CLINICAL CHARACTERISTICS
9/11/20
Ng JJ, Luo Y, Phua K, et al. | J Infect
Aim: To quantitatively synthesized available literature and performed a single-arm meta-analysis of proportions to report the pooled incidence rate of AKI and renal replacement therapy (RRT) use in hospitalized patients with COVID-19.
CLINICAL CHARACTERISTICS
9/11/20
Patel U, Malik P, Usman MS, et al. | SN Compr Clin Med
Aim: To identify risk factors associated with poor outcomes (IMV and mortality) of COVID-19 hospitalized patients.
CLINICAL CHARACTERISTICS
9/11/20
Bakhtawar N, Usman M, Khan MMU | Cureus
Aim: To evaluate the efficacy of convalescent plasma (CP) therapy and its effects on COVID-19 patient outcomes.
CANDIDATE THERAPEUTICS
9/11/20
Paliogiannis P, Mangoni AA, Dettori P, et al. | Front Public Health
Aim: To investigate differences in serum D-dimer concentrations in patients with and without severe COVID-19 disease. 
CLINICAL CHARACTERISTICS
9/11/20
Sant'Ana G, Imoto AM, Amorim FF, et al. | Acta Paul Enferm
Aim: To identify evidences regarding infection by SARS-CoV-2 and deaths of healthcare workers and related-risk factors.
INFECTION CONTROL
9/11/20
Pathak SK, Salunke AA, Thivari P, et al. | Diabets Metab Syndr
Aim: To evaluate the efficacy of hydroxychloroquine and its related formulations in COVID-19 patients.
CANDIDATE THERAPEUTICS
9/11/20
Zhao G, Huang P, Du B, et al. | Nutr Metab Cardiovasc Dis
Aim: To 1) explore the prevalence of cardiac injury in different types of COVID-19 patients and 2) evaluate the association between cardiac injury and worse prognosis (severe disease, admission to ICU, and mortality) in patients with COVID-19.
CLINICAL CHARACTERISTICS
9/11/20
Lenferink LIM, Meyerbroker K, Boelen PA | Psychiatry Res
Aim: To review the evidence on online Eye Movement Desensitization and Reprocessing (EMDR) treatment for PTSD.
9/11/20
Czumbel LM, Kiss S, Farkas N, et al. | Front Med
Aim: To conduct a meta-analysis on the reliability and consistency of SARS-CoV-2 viral RNA detection in saliva specimens.
UPDATED
DIAGNOSTICS
9/11/20
Abdoul-Azize HT, El Gamil R | Glob Soc Welf
Aim: To explore the current implementation of social protection programs during the COVID-19 pandemic in the most affected countries as well as to provide learned lessons from countries that had not previously considered implementing social protection programs up until the COVID-19 crisis. 
9/11/20
Heidary F, Gharebaghi R | Expert Rev Clin Immunol
Aim: To review the evidence on the antiviral effects of TRIM56.
9/11/20
Seidu S, Gillies C, Zaccardi F, et al. | Endocrinol Diabetes Metab
Aim: To determine whether people with overweight or obesity and with SARS?CoV?2 have different outcomes compared to those within normal weight thresholds.
UPDATED
CLINICAL CHARACTERISTICS
9/11/20
Rahman HS, Aziz MS,Hussein RH, et al. | Int J Surg Open
Aim: To review the evidence on the causative agent, the main modes of transmission, and sources of COVID-19.
INFECTION CONTROL
9/10/20
Neishaboori AM, Moshrefiaraghi D, Ali KM, et al. | Arch Acad Emerg Med
Aim: To investigate the current evidence regarding central nervous system (CNS) complications in patients with confirmed COVID-19.
CLINICAL CHARACTERISTICS
9/10/20
Chastain DB, Stitt TM, Ly PR, et al. | Open Forum Infect Dis
Aim: To assess potential proinflammatory targets and review the safety and efficacy of immunomodulatory therapies in managing patients with acute respiratory distress syndrome associated with coronavirus disease 2019.
CANDIDATE THERAPEUTICS
9/10/20
Flumignan RLG, Nakano LCU, Pascoal PIF, et al. | Sao Paulo Med J
Aim: To identify and summarize the evidence from Cochrane systematic reviews (SRs) regarding measures for controlling the dissemination of COVID-19 infection.
INFECTION CONTROL
9/10/20
Housing for Health Project | University of Alberta
Aim: To review the evidence on the built environment factors associated with physical activity among older adults during the acute and recovery phases of the COVID-19 and future pandemics.
9/10/20
Tricco A | Drug Safety and Effectiveness Network
Aim: To review the evidence on the safety and effectiveness of using fractional dosing strategies to deliver intramuscular seasonal influenza vaccines.
9/10/20
Serban D, Smarandache CG, Tudor C, et al. | Diagnostics
Aim: To review the available evidence regarding the health risk of the aerosolization induced by laparoscopy induced and impact of the COVID-19 pandemic upon minimally invasive surgery.
INFECTION CONTROL
9/10/20
Liu C, Yang J, Wang W, et al. | Eur J Gastroenterol Hepatol
Aim: To compare liver injury in severe vs. non-severe or dead vs. surviving patients and investigate whether livery injury can help predict clinical severity and mortality in patients with coroanvirus disease 2019.
DIAGNOSTICS
9/10/20
Cyr G, Gabet M | Centre de Recherche en Sante Publique
Aim: To review the evidence on the best practices for managing a regional coordination center in a crisis situation.
9/10/20
Bondini CM, Sage S, Wilson BP, et al. | Int Wound J
Aim: To explore the existing evidence around alternative service delivery modalities for treating complex wounds.
INFECTION CONTROL
9/10/20
García Ron A, Cuéllar-Flores I | An Pediatr
Aim: To review the available evidence on the psychological impact of confinement in children, seeking to identify the main stressors and protective factors at play.
MENTAL HEALTH
9/10/20
Lester S, Khatwa M, Sutcliffe K | JAMA Intern Med
Aim: To gain a deeper understanding of the kinds of services that young people exposed to ACEs feel they need.
9/10/20
Seyedpour S, Khodaei B, Loghman AH, et al. | J Cell Physiol
Aim: To provide a systematic evaluation of the most recent in vitro and in vivo investigations targeting SARS?CoV?2 cell entry. 
CLINICAL CHARACTERISTICS
9/10/20
Major R, Selvaskandan H, Makkeyah YM, et al. | J Am Soc Nephrol
Aim:  To assess the CKD-related inclusion and exclusion criteria for COVID-19 trials.
9/10/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
Aim: To review the evidence on the long-term impacts of COVID-19 on infection survivors.
9/9/20
Fu EL, Janse RJ, de Jong Y, et al. | Clin Kidney J
Aim: To review the evidence on incidence, mortality and risk factors for acute kidney injury in hospitalized COVID-19 patients.
CLINICAL CHARACTERISTICS
9/9/20
Razmi M, Hashemi F, Gheytanchi E, et al. | Int Immunopharmacol
Aim: To assess the available data regarding the efficacy of the immunomodulatory drugs used to manage COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/9/20
Kow CS, Hasan SS | J Med Virol
Aim: To explore whether the use of metformin was associated with decreased mortality in COVID-19 patients.
CANDIDATE THERAPEUTICS
9/9/20
Chauhan N, Soni S, Gupta A, et al. | Expert Rev Mol Diagn
Aim: To review the evidence on diagnostic methods for COVID-19 detection.
DIAGNOSTICS
9/9/20
Gitterman LMT, Feris SNV, von Oetinger Giocoman A | Neurologia
Aim: To analyze the available evidence on patients with Guillain-Barre syndrome associated with COVID-19.
CLINICAL CHARACTERISTICS
9/9/20
Seyedpour S, Khodaei B, Loghman AH, et al. | J Cell Physiol
Aim: To provide a systematic evaluation of the most recent in vitro and in vivo investigations targeting SARS?CoV?2 cell entry.
CANDIDATE THERAPEUTICS
9/8/20
Wong Y, Tan M, Zheng Q, et al. | Ann Hepatol
Aim: To assess the prevalence and degree of liver injury between patients with severe and non-severe COVID-19.
CLINICAL CHARACTERISTICS
9/8/20
Miller MA, Cappuccio F | Sleep Med Rev
Aim: To review the rapidly emerging COVID-19 literature to determine (a) the relationship between obstructive sleep apnoea (OSA) and adverse COVID-19 outcomes and, (b) potential causal mechanisms (c) what effect COVID-19 has had on OSA diagnosis and (d) what effect COVID-19 has had on treatment and management of OSA during this period. 
CLINICAL CHARACTERISTICS
9/8/20
Kaushik A, Gupta S, Sood M, et al. | Pediatr Infect Dis J
Aim: To review the evidence on multisystem inflammatory syndrome in children (MIS-C).
CLINICAL CHARACTERISTICS
9/8/20
Hartmann-Boyce J, Gunnell J, Drake J, et al. | BMJ Evid Based Med
Aim: To assess the risks and management considerations of COVID-19 in people with asthma (PWA).
CLINICAL CHARACTERISTICS
9/8/20
Elavarasi A, Prasad M, Seth T, et al. | J Gen Intern Med
Aim: To synthesize the available data on the efficacy and safety of CQ and HCQ for the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/8/20
Fraser J, Mousley J, Testro A, et al. | Transplant Proc
Aim: To review the evidence on the clinical presentation, treatments, and outcomes in liver transplant recipients with COVID-19.
CLINICAL CHARACTERISTICS
9/8/20
Zang Y, Han X, He M, et al. | Naunyn Schmiedebergs Arch Pharmacol
Aim: To systematically assess the benefits and harms of HCQ for the treatment of COVID-19.
CANDIDATE THERAPEUTICS
9/8/20
Vargas M, Servillo G, Einav S | Eur Rev Med Pharmacol Sci
Aim: To review the evidence on the use of lopinavir/ritonavir for the treatment of SARS, MERS, and SARS-CoV-2.
CANDIDATE THERAPEUTICS
9/8/20
Shoar S, Hosseini F, Naderan M, et al. | Am J Cardiol
Aim: To review the evidence on cardiovascular complications associated with COVID-19.
CLINICAL CHARACTERISTICS
9/8/20
Radia T, Williams N, Agrawal P, et al. | Paediatr Respir Rev
Aim: To evaluate reported cases of MIS-C in children and adolescents.
CLINICAL CHARACTERISTICS
9/8/20
Wittmeier K, Parsons J, Webber S, et al. | Phys Ther
Aim: To provide a review of the pandemic and physical disaster management literature to summarize physical therapy–specific operational considerations to assist hospital-based leadership teams in planning and response efforts during the COVID-19 pandemic.
INFECTION CONTROL
9/8/20
Barbosa MT, Sousa CS, Morais-Almeida M, et al. | COPD
Aim: To review the effectiveness of telemedicine to treat COPD during the COVID-19 pandemic.
INFECTION CONTROL
9/8/20
Diriba K, Awulachew E, Getu E | Eur J Med Res
Aim: To assess the effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and its possibility of vertical maternal–fetal transmission.
CLINICAL CHARACTERISTICS
9/8/20
Samaranayake LP, Fakhruddin KS, Ngo HC, et al. | Acta Odontol Scand
Aim: To review the data on the effectiveness and efficacy of facemasks and respirators, including protective eyewear, with particular emphasis on dental healthcare.
INFECTION CONTROL
9/8/20
Barello S, Falco-Pegueroles A, Rose D, et al. | Int J Public Health
Aim: To assess available literature on perceived stress and psychological responses to influenza pandemics in HCWs and identify implications for healthcare practice and future research.
MENTAL HEALTH
9/8/20
Kashi AH, De la Rosette J, Amini E, et al. | Urol J
Aim: To review the current literature on the presence of COVID-19 virus in the urine of infected patients and to explore the clinical features that can predict the presence of COVID-19 in urine.
INFECTION CONTROL
9/7/20
Simadibrata DM, Lubis AM | Epidemiol Infect
Aim: To review and evaluate currently available evidence to establish the association between D-dimer levels on admission and all-cause mortality risk in patients with COVID-19.
CLINICAL CHARACTERISTICS
9/4/20
Sarkar S, Khanna P, Soni KD | J Med Virol
Aim: To evaluate the impact of glucocorticoid therapy in COVID-19 patients based on the publications reported to date.
CANDIDATE THERAPEUTICS
9/4/20
Keller KG, Reangsing C, Schneider JK | J Adv Nurs
Aim: To 1) determine the clinical presentation and 2) outcomes of adult hospitalized patients with COVID-19 to provide practicing nurses with a cogent and concise clinical impression of COVID-19 patients.
CLINICAL CHARACTERISTICS
9/4/20
Rees EM, Nightingale ES, Jafari Y, et al. | BMC Med
Aim: To review estimates of how long patients with COVID-19 need different levels of hospital care.
UPDATED
CLINICAL CHARACTERISTICS
9/4/20
Ghoda A, Ghoda M | Cureus
Aim: To ascertain whether liver enzyme derangement is a common feature in adult patients with confirmed COVID-19 infection, determine the relation of deranged liver enzymes with outcome or mortality in COVID-19, and determine if liver failure is a common feature of COVID-19.
CLINICAL CHARACTERISTICS
9/4/20
Stavridou A, Stergiopoulou A, Panagouli E, et al. | Psychiatry Clin Neurosci
Aim: To review the evidence on psychosocial consequences of COVID-19 in children, adolescents and young adults.
MENTAL HEALTH
9/3/20
Giorli A, Ferretti F, Biagini C, et al. | Curr Treat Options Neurol
Aim: To investigate the association between the olfactory dysfunction and the more typical symptoms (fever, cough, dyspnoea) within the Sars-CoV-2 infection (COVID-19) in hospitalized and non-hospitalized patients.
CLINICAL CHARACTERISTICS
9/3/20
Martin A, Blom IM, Whyatt G, et al. | Disaster Med Public Health Prep
Aim: To explore the involvement of medical students in past global health emergencies, to help inform current and future scenarios.
UPDATED
9/3/20
Caldeira D, Alves M, Melo RGE, et al. | Int J Cardiol Heart Vasc
Aim: To systematically evaluate the risk of COVID-19 infection and the risk of severe COVID-19 disease associated with previous exposure to (ACEi) and/or ARB).
UPDATED
CLINICAL CHARACTERISTICS
9/3/20
Liu C, He Y, Liu L, et al. | BMC Pediatr
Aim: To review the evidence on the characteristics of children with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
9/3/20
Zhang Z, Zhang L, Zha D, et al. | Ren Fail
Aim: To evaluate the clinical characteristics and possible risk factors affecting the progression of disease in COVID-19 patients with AKI.
CLINICAL CHARACTERISTICS
9/3/20
Allotey J, Stallings E, Bonet M, et al. | BMJ
Aim: To determine the clinical manifestations, risk factors, and maternal and perinatal outcomes in pregnant and recently pregnant women with suspected or confirmed coronavirus disease 2019 (covid-19).
UPDATED
CLINICAL CHARACTERISTICS
9/3/20
de Camargo MC, Martinez-Silveira MS, Lima AA, et al. | Cien Saude Colet
Aim: To evaluate the effectiveness of non-woven face masks for the prevention of respiratory infections (MERS CoV, SARS-CoV, and SARS-CoV-2) in the population.
INFECTION CONTROL
9/3/20
Sergeant A, van Reekum EA, Sanger N, et al. | BMJ Open
Aim: To study the effect of pandemics and epidemics on mental health outcomes for people with premorbid mental disorders.
UPDATED
9/3/20
de Andrade KRC, da Silva Carvalho VK, Farinasso CM, et al. | Cien Saude Colet
Aim: To evaluate the effects of drug therapies for coronavirus infections. 
CANDIDATE THERAPEUTICS
9/3/20
Bendezu-Quispe G, Rodirquez-Zuniga MJM, Roman YM, et al. | Rev Peru Med Exp Salud Publica
Aim: To review the evidence on chloroquine/hydroxychloroquine, lopinavir/ritonavir, tocilizumab, oseltamivir, interferon, atazanavir and anti SARS-CoV-2 serum as therapeutic agents for COVID-19.
CANDIDATE THERAPEUTICS
9/3/20
Bentlage E, Ammar A, How D, et al. | Int J Environ Res Public Health
Aim: To provide practical recommendations for maintaining active lifestyles during pandemics.
INFECTION CONTROL
9/3/20
 | Health Information and Quality Authority, Ireland
Aim: To review guidance for residential care facilities in the context of COVID-19.
9/3/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the risk of adverse maternal or fetal outcomes in women diagnosed with COVID-19 during pregnancy.
9/3/20
de Barcelos Ubaldo Martins L, Jabour LGPP, Vieira CC, et al. | Curr Med Chem
Aim: To describe the particularities of the RAS and the immune system profile of particular subgroups of patients.
CLINICAL CHARACTERISTICS
9/3/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the volume-outcome relationship for surgical interventions.
9/3/20
Costenaro P, Minotti C, Barbieri E, et al. | Rev Med Virol
Aim: To review the current knowledge on SARS-CoV-2 cases in PLWHA.
UPDATED
CLINICAL CHARACTERISTICS
9/3/20
de Almeida-Pititto B, Dualib PM, Zajdenverg L, et al. | Diabetol Metab Syndr
Aim: To evaluate the association of diabetes, hypertension, cardiovascular disease and ACEI/ARBs exposure with severity–intensive care unit treatment or mechanical ventilation necessity or O2 saturation?
UPDATED
CLINICAL CHARACTERISTICS
9/2/20
Cheruiyot I, Kipkorir V, Ngure B, et al. | Ann Vasc Surg
Aim: To identify and consolidate evidence of AT in COVID-19 patients.
CLINICAL CHARACTERISTICS
9/2/20
Marasinghe KM | Int J One Health
Aim: To understand available evidence around the effectiveness or ineffectiveness of face mask use in limiting the spread of COVID-19 among individuals who have not yet been diagnosed with COVID-19
INFECTION CONTROL
9/2/20
Saini KS, Tagliamento M, Lambertini M, et al. | Eur J Cancer
Aim: To provide precise estimates of the mortality rate among patients with both cancer and COVID-19.
CLINICAL CHARACTERISTICS
9/2/20
Cumpstey AF, Oldman AH, Smith AF, et al. | Cochrane Database of Systematic Reviews
Aim: To address how oxygen therapy should be targeted in adults with ARDS (particularly ARDS secondary to COVID?19 or other respiratory viruses) and requiring mechanical ventilation in an intensive care unit, and the impact oxygen therapy has on mortality, days ventilated, days of catecholamine use, requirement for renal replacement therapy, and quality of life.
CANDIDATE THERAPEUTICS
9/2/20
Chan CK, Huang YS, Liao HW, et al  | Hypertension
Aim: To review the evidence on the impact of the use of ACEi or ARBs on SARS-CoV-2 infection.
CANDIDATE THERAPEUTICS
9/2/20
Gebru AA, Birhanu T, Wendimu E, et al. | Hum Antibodies
Aim: To identify and review a published level of risk, effects response to potential health emergencies, prevention, and control methods of Coronavirus Disease 2019 at the global level.
INFECTION CONTROL
9/1/20
Sakka M, Conners JM, Hekimian G, et al. | J Med Vasc
Aim: To review current available data on the association between D-Dimer levels and mortality in patients admitted to hospital for COVID-19.
CLINICAL CHARACTERISTICS
9/1/20
Vafea MT, Atalla E, Kalligeros M, et al. | Clin Radiol
Aim: To determine the overall rate of chest imaging findings in asymptomatic cases, describe the most common patterns found, and determine the rate of later symptom development in these initially asymptomatic cases.
CLINICAL CHARACTERISTICS
9/1/20
Ahmed J, Rizwan T, Malik F, et al. | Cureus
Aim: To derive generalizable, well-powered estimates of liver injury prevalence in COVID-19 patients. 
CLINICAL CHARACTERISTICS
9/1/20
Gomez-Ochoa SA, Franco OH, Rojas LZ, et al. | Am J Epidemiol
Aim: To systematically review the evidence on the prevalence, risk factors, clinical characteristics, and prognosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among HCW.
9/1/20
Leal J, Gagnon H | Alberta Health Services
Aim: To review the evidence on transmission of COVID-19 in condos, apartments, and/or hotels.
9/1/20
Gagnon MP | Universite Laval
Aim: To review the evidence on effective digital health interventions to prevent, detect, and manage mental health problems in individuals with a pre-existing chronic diseases.
9/1/20
Liu M, Ya G, Yuan Y, et al. | Integr Med Res
Aim: To evaluate the efficacy and safety of LH for treating patients with COVID-19 by a systematic review and meta-analysis.
CANDIDATE THERAPEUTICS
9/1/20
Lapid MI, Seiner S, Heintz H, et al. | Am J Geriatr Psychiatry
Aim: To provide a consensus statement on the clinical practice changes in ECT specific to older adults based on expert group discussions of ECT practitioners across the country and a systematic review of the literature. 
INFECTION CONTROL
9/1/20
Sharpe H | Alberta Health Services
Aim: To review the evidence on the harm of mask use in specific patient populations.
9/1/20
Allison P, de Souza RF, Aboud L, et al. | Public Health Agency of Canada
Aim: To review the evidence on safe dental practices during the COVID-19 pandemic.
9/1/20
Clements F | University of Calgary, Health Technology Assessment Unit
Aim: To review the evidence on the immunogenicity and safety of the influenza vaccine at reduced or regular intradermal doses compared with a full intramuscular dose.
9/1/20
Smale J | Timiskamig Health Unit
Aim: To review the harms being experienced by community dwelling low income populations from staying at home for long periods of time during current or past pandemics.
9/1/20
Baroutjian A, Sanchez C, Boneva D, et al. | Am J Emerg Med
Aim: To evaluate the safety and effectiveness of SARS-CoV-2 pharmacologic therapies as of August 2, 2020 according to study level of evidence.
CANDIDATE THERAPEUTICS
9/1/20
Park R, Chidharla A, Mehta K, et al. | EClinicalMedicine
Aim: To synthesize the evidence behind sex-bias within COVID-19 associated illness severity and death specifically within the cancer patient population.
CLINICAL CHARACTERISTICS
9/1/20
Erdmann R | Alberta Health Services
Aim: To review the evidence on the risk factors associated with the development of severe outcomes in COVID-19.
9/1/20
Carroll A, Hicks A, Saxinger L, et al. | Alberta Health Services
Aim: To review the evidence on the role of children in community SARS-CoV-2 transmission.
8/31/20
Usher K, Jackson D, Durkin J, et al. | Int J Ment Health Nurs
Aim: To systematically examine, synthesise and critically appraise the available evidence on the relationship between pandemic-related behaviours and psychological outcomes.
MENTAL HEALTH
8/31/20
McBane RD, Roldan VDT, Niven AS, et al. | Mayo Clin Proc
Aim: To synthesize current data on thrombosis risk, prognostic implications, and anticoagulation effects in COVID-19.
CLINICAL CHARACTERISTICS
8/31/20
Ssentongo P, Ssentongo AE, Heilbrunn ES, et al. | PLoS ONE
Aim: To estimate the association of pre-existing comorbidities with COVID-19 mortality.
UPDATED
CLINICAL CHARACTERISTICS
8/31/20
Dhir SK, Kumar J, Meena J, et al. | J Trop Pediatr
Aim: To systematically synthesize the currently available literature on various modes of transmission (congenital, intrapartum, and postpartum), clinical features and outcomes of SARS-CoV-2 infection in neonates.
INFECTION CONTROL
8/31/20
Chi H, Chiu N, Tai Y, et al. | J Microbiol Immunol Infect
Aim: To investigate the outcomes of neonates born to mothers with COVID-19.
CLINICAL CHARACTERISTICS
8/31/20
Pal R, Banerjee M, Yadav U, et al. | Diabetes Metab Syndr
Aim: To conduct a systematic literature review and analyze the demographic/biochemical parameters and clinical outcomes of COVID-19 patients with diabetic ketoacidosis (DKA) and combined DKA/HHS (hyperglycemic hyperosmolar syndrome).
CLINICAL CHARACTERISTICS
8/31/20
Bakhtawar N, Usman M, Khan MHU | Cureus
Aim: To provide an insight into the clinical effectiveness of convalescent plasma as a potential therapy for COVID-19 patients.
CANDIDATE THERAPEUTICS
8/31/20
Mousavi E, Kananizadeh N, Martinello R, et al. | Environ Sci Technol
Aim:  To review the evidence on the safety of air filtration and air recirculation in healthcare premises. 
INFECTION CONTROL
8/31/20
Rego GNA, Nucci MP, Alves AH, et al. | Vaccines
Aim: To summarize the global race for vaccine development against COVID-19. 
INFECTION CONTROL
8/31/20
Gordon M, Patricio M, Horne L, et al. | Med Teach
Aim: To synthesize published reports of medical educational developments in response to the pandemic, considering descriptions of interventions, evaluation data and lessons learned.
INFECTION CONTROL
8/31/20
Fiolet T, Guihur A, Rebeaud M, et al. | Clin Microbiol Infect
Aim: To assess whether chloroquine or hydroxychloroquine with or without azithromycin decreased COVID-19 mortality compared to the standard of care.
UPDATED
CANDIDATE THERAPEUTICS
8/31/20
Das RR, Jaiswal N, Dev N, et al. | Front Med
Aim: To review the evidence on the efficacy and safety of using anti-malarial drugs to treat COVID-19.
CANDIDATE THERAPEUTICS
8/31/20
Del Sole F, Farcomeni A, Loffredo L, et al. | Eur J Clin Invest
Aim: To systematically review clinical and biochemical characteristics associated with the severity of the novel severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2)?related disease (COVID?19).
CLINICAL CHARACTERISTICS
8/31/20
Uncini A, Vallat J, Jacobs BC | J Neurol Neurosurg Psychiatry
Aim: To clarify the clinical and electrophysiological phenotype, and to discuss, on the basis of the available data, whether the disease mechanism could be parainfective or postinfective and to speculate on the possible pathogenesis.
CLINICAL CHARACTERISTICS
8/31/20
Lei H, Xu X, Xiao S, et al. | J Infect
Aim: To assess the secondary attack rate of household COVID-19 transmission.
INFECTION CONTROL
8/31/20
Zhang C, Shen L, Le K, et al. | Front Cardiovasc Med
Aim: To summarize all available evidence for a comprehensive and rigorous systematic review focused on VTE incidence in hospitalized COVID-19 patients.
CLINICAL CHARACTERISTICS
8/31/20
Popkin BM, Du S, Green WD, et al. | Obes Rev
Aim: To review the evidence on the linkage between obesity and COVID-19.
CLINICAL CHARACTERISTICS
8/31/20
El Boghdady M, Ewalds-Kvist B | Surgeon
Aim: To systematically review the literature regarding the safe use of laparoscopy during COVID-19.
INFECTION CONTROL
8/31/20
Shorey S, Chan V, et al. | Midwifery
Aim: To consolidate qualitative research studies that examined the experiences and needs of pregnant women, midwives, and nurses of maternity units to provide a way forward for future research and practices during the current pandemic and future epidemics and pandemics.
INFECTION CONTROL
8/31/20
Soklaridis S, Lin E, Lalani Y, et al. | Gen Hosp Psychiatry
Aim: To provide an up-to-date and robust synthesis of the evidence by reporting on implementation, evaluation, and outcomes regarding mental health interventions during medical pandemics within the last two decades.
MENTAL HEALTH
8/31/20
Almqvist J, Granberg T, Tzortzakakis A, et al. | Ann Clin Transl Neurol
Aim: To optimize diagnostic workup of the current severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) pandemic.
DIAGNOSTICS
8/31/20
Chi H, Chiu N, Peng C, et al. | Life
Aim: To investigate the prevalence of OGA in COVID-19 patients.
CLINICAL CHARACTERISTICS
8/31/20
Daphine J, Hebert PC, Ziegler D, et al. | Crit Care Med
Aim: To identify and appraise articles describing criteria used to prioritize or withhold a critical care admission.
INFECTION CONTROL
8/31/20
Bueno-Notivol J, Gracia-Garcia P, Olaya B, et al. | Int J Clin Health Psychol
Aim: To systematically review community-based studies on depression conducted during the COVID-19 and estimate the pooled prevalence of depression.
MENTAL HEALTH
8/31/20
Derraik JGB, Anderson WA, Connelly EA, et al. | Int J Environ Res Public Health
Aim: To summarize the existing literature on the viability of SARS-CoV-2, the efficacy of key potential disinfection procedures against the virus (specifically ultraviolet light and heat), and the impact of these procedures on FFR performance, material integrity, and/or fit.
INFECTION CONTROL
8/31/20
Jani BD, Pell JP, McGagh D, et al. | BJGP Open
Aim: To collate a comprehensive list of symptoms, assessment items, demographics, and lifestyle and health conditions associated with COVID-19, with proposed corresponding SNOMED CT clinical terms. 
CLINICAL CHARACTERISTICS
8/31/20
Duarte ML, Dos Santos LR, de Souza Contencas AC, et al. | Sao Paulo Med J
Aim: To compare accuracy between RT-PCR and computed tomography (CT) for detecting COVID-19 in the first week of its symptoms during the pandemic.
DIAGNOSTICS
8/31/20
Ullah W, Abdullah HM, Roomi S, et al. | J Clin Med Res
Aim: To review the evidence on the use of hydroxycholorquine to treat COVID-19.
CANDIDATE THERAPEUTICS
8/31/20
Sawalha K, Abozenah M, Kadado AJ, et al. | Cardiovasc Revasc Med
Aim: To describe the clinical characteristics and management of currently published COVID-19 myocarditis patients.
CLINICAL CHARACTERISTICS
8/31/20
Nasir M, Perveen RA, Saha SK, et al. | Mymensingh Med J
Aim: To evaluate the role of favipiravir along with its safety and efficacy for the patients who are suffering from severe acute respiratory distress syndrome due to CoronaVirus-2 (SARS-CoV-2) as re-purposeful use.
CANDIDATE THERAPEUTICS
8/31/20
Hasani H, Mardi S, Shakerian S, et al. | Biomed Res Int
Aim: To assess the frequency of clinical, laboratory, and imaging featues of COVID-19.
CLINICAL CHARACTERISTICS
8/31/20
Copat C, Cristaldi A, Fiore M, et al. | Environ Res
Aim: To provide an update state of art relating the role of air pollution, in particular PM2.5, PM10 and NO2, in COVID-19 spread and lethality.
INFECTION CONTROL
8/31/20
Centeno-Tablante E, Medina-Rivera M, Finkelstein J, et al. | Ann N Y Acad Sci
Aim: To capture information that might necessitate changes in the guidance on breast milk and breastfeeding given the uncertainty in this area.
8/31/20
Porfidia A, Valeriani E, Pola R, et al. | Thromb Res
Aim: To evaluate the incidence of VTE in patients with COVID-19.
CLINICAL CHARACTERISTICS
8/29/20
Kelada M, Anto A, Dave K, et al. | Cureus
Aim: To assess the role of sex in the risk of mortality from COVID-19 in adult patients through comparison of clinical markers and inflammatory indexes.? 
UPDATED
CLINICAL CHARACTERISTICS
8/28/20
Yu J, Wu B, Yang J, et al. | Biol Res Nurs
Aim: To explore whether cardio-cerebrovascular disease would increase the risk of COVID-19 patients. 
CLINICAL CHARACTERISTICS
8/27/20
Braithwaite I, Callender T, Bullock M, et al. | Lancet Digit Health
Aim: To assess the effectiveness of automated and semi-automated digital tools for contact tracing, and identify key considerations for successful implementation, to inform the control of COVID-19. 
UPDATED
INFECTION CONTROL
8/27/20
Prodromos CC | New Microbes New Infect
Aim: To review the evidence on cardiac arrhythmic mortality caused by the use of hydroxychloroquine and azithromycin.
CANDIDATE THERAPEUTICS
8/27/20
Coomes EA, Haghbayan H | Rev Med Virol
Aim: To assess the evidence describing IL-6 response in patients with COVID-19 and the existing and planned studies investigating the efficacy of tocilizumab to guide patient management, clarify guideline development, and inform future trials in this field.
UPDATED
CLINICAL CHARACTERISTICS
8/27/20
Gertsman S, Agarwal A, O'Hearn K, et al. | J Hosp Infect
Aim: To collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-based treatments, with special attention to impact on mask function (aerosol penetration, airflow resistance), fit, and physical traits.
UPDATED
INFECTION CONTROL
8/27/20
Laufs J, Waseem Z | Int J Disaster Risk Reduct
Aim: To explore the short- and long-term effects of epidemics on policing.
INFECTION CONTROL
8/26/20
Zou F, Qian Z, Wang Y, et al. | CJC Open
Aim: To conduct a comprehensive review and meta-analysis of the incidence, comorbidities, outcomes and possible mechanisms of acute cardiac injury in COVID-19 patients.
CLINICAL CHARACTERISTICS
8/26/20
Pang W, Liu Z, Li Y, et al. | Integr Med Res
Aim: To evaluate the efficacy and safety of CMD for COVID-19.
CANDIDATE THERAPEUTICS
8/26/20
Arentz S, Yang G, Goldenberg J, et al. | Adv Integr Med
Aim: To assess the effects of zinc on the incidence, duration and severity of acute upper or lower respiratory tract infections caused by SARS-CoV-2 infection in people of any age and of any zinc status when used as a preventive supplement or as a therapy.
CANDIDATE THERAPEUTICS
8/26/20
Schloss J, Lauche R, Harnett J, et al. | Adv Integr Med
Aim: To review the evidence on the effect of Vitamin C on acute respiratory tract infections in adults when administered at the onset of symptoms.
CANDIDATE THERAPEUTICS
8/26/20
Kaur N, Gupta I, Singh H, et al. | SN Compr Clin Med
Aim: To evaluate the epidemiological and clinical characteristics of COVID-19 patients while also highlighting the comorbidities and radiological findings.
CLINICAL CHARACTERISTICS
8/26/20
Rai B, Shukla A, Dwivedi LK | Clin Epidemiol Glob Health
Aim: To review the qualitative and quantitative synthesis of the currently available evidence for the serial interval of COVID-19.
INFECTION CONTROL
8/26/20
Abu-Rumeileh S, Abdelhak A, Foschi M, et al. | J Neurol
Aim: To provide a comprehensive and updated overview of all case reports and series of COVID-19-related GBS to identify predominant clinical, laboratory, and neurophysiological patterns and to discuss the possible underlying pathophysiology.
CLINICAL CHARACTERISTICS
8/26/20
Bansal A, Prasad JB | Z Gesundh Wiss
Aim: To quantify the overall risk of liver damage in COVID-19 patients and also find the overall variation in risk outcome.
CLINICAL CHARACTERISTICS
8/26/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the medium- and long-term health sequelae of COVID-19 infection among survivors.
8/26/20
Said M, Ngo V, Hwang J, et al. | Laryngoscope Investig Otolaryngol
Aim: To review applications of telemedicine for the evaluation of facial trauma to better direct utilization of these methods and technologies during times of limited access to clinical resources such as the COVID?19 pandemic.
INFECTION CONTROL
8/26/20
Correia AO, Feitosa PWG, Moreira JLS, et al. | Neurol Psychiatry Brain Res
Aim: To describe the main neurological manifestations related to coronavirus infection in humans.
CLINICAL CHARACTERISTICS
8/26/20
D'Ambrosi R | Indian J Orthop
Aim: To analyze all the articles related to COVID-19 and orthopedics and to shed light on the scientific evidence that has actually been found.
CLINICAL CHARACTERISTICS
8/26/20
Kotwal A, Yadav A, Kotwal J | Med J Armed Forces India
Aim: To assess correlation between predicted and actual values of cases in India.
8/26/20
Dinnes J, Deeks JJ, Adriano A et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of point-of-care antigen and molecular-based tests to determine if a person presenting in the community or in primary or secondary care has current SARS-CoV-2 infection
DIAGNOSTICS
8/26/20
Frediansyah A, Nainu F, Dhama K, et al. | Clin Epidemiol Glob Health
Aim: To summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19.
CANDIDATE THERAPEUTICS
8/26/20
Khalil A, Kalafat E, Benlioglu C, et al. | EClinicalMedicine
Aim: To systematically review the available literature on COVID-19 and pregnancy, to provide comprehensive data to care-providers, pregnant women and their families, inform national and international guidelines, and direct the course of ongoing and future studies
CLINICAL CHARACTERISTICS
8/26/20
Hariyanto TI, Kurniawan A | Diabetes Metab Syndr
Aim: To analyze the association between statin use and in-hospital outcomes of COVID-19 infection.
CANDIDATE THERAPEUTICS
8/26/20
Siordia JA, Bernaba M, Yoshino K, et al. | SN Compr Clin Med
Aim: To compile the current data regarding human controlled COVID-19 treatment trials.
CANDIDATE THERAPEUTICS
8/26/20
Leeson CE, Ismail A, Hashad MM, et al. | SN Compr Clin Med
Aim: To review and summarize what is known about COVID-19 and the current implications of intravesical BCG with regard to the disease.
CANDIDATE THERAPEUTICS
8/26/20
Aucoin M, Cooley K, Saunders PR, et al. | Adv Integr Med
Aim: To review the role of quercetin in the treatment and recovery of COVID-19 and other respiratory tract infections.
CANDIDATE THERAPEUTICS
8/26/20
Aucoin M, Cooley K, Saunders PR, et al. | Adv Integr Med
Aim: To review the role of Echinacea in the prevention and treatment of COVID-19 and other respiratory tract infections.
CANDIDATE THERAPEUTICS
8/26/20
Nieto I, Navas JF, Vazquez C | Brain Behav Immun Health
Aim: To examine compliance with basic methodological quality criteria and open scientific research practices on the mental health effects of the COVID-19 pandemic.
8/26/20
Davis B, Rothrock AN, Swetland S, et al. | J Am Coll Emerg Physicians Open
Aim: To analyze the prevalence of respiratory pathogens (viruses and atypical bacteria) in COVID?19 patients.
CLINICAL CHARACTERISTICS
8/25/20
Chirico F, Sacco A, Bragazzi NL, et al. | Int J Environ Res Public Health
Aim: To evaluate the COVID-19 risk associated with the presence of air-conditioning systems.
INFECTION CONTROL
8/25/20
Baral R, White M, Vassiliou VS | Curr Atheroscler Rep
Aim: To review the evidence on the impact RAAS inhibitor use has in antihypertensive COVID-19 hospitalised patients.
UPDATED
CANDIDATE THERAPEUTICS
8/25/20
Kunutsor SK, Laukkanen JA | Thromb Res
Aim: To review the evidence on the thromboembolic complications associated with COVID-19 and the incidence of severe disease.
CLINICAL CHARACTERISTICS
8/25/20
Krishnamoorthy Y, Nagarajan R, Saya GK, et al. | Psychiatry Res
Aim: To quantify the prevalence of various psychological morbidities among general population, healthcare workers and COVID-19 patients amidst the COVID-19 pandemic.
MENTAL HEALTH
8/25/20
van Doorn AS, Meijer B, Frampton CMA, et al. | Aliment Pharmacol Ther
Aim: To critically assess the clinical relevance of testing stool samples and anal swabs and provide an overview of the potential faecal-oral transmission of SARS-CoV-2.
DIAGNOSTICS
8/24/20
Puli S, Baig M, Walayat S | Cureus
Aim: To assess gastrointestinal symptoms and liver enzymes trend in corona virus infection.
CLINICAL CHARACTERISTICS
8/24/20
Patanavanich R & Glantz SA | Nicotine & Tobacco Research
Aim: To review the evidence on the association between smoking and progression of the infectious disease COVID-19.
CLINICAL CHARACTERISTICS
8/23/20
Jovic TH, Ali SR, Ibrahim N, et al. | Nutrients
Aim: To investigate whether vitamin supplementation is beneficial in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/23/20
Starke KR, Petereit-Haack G, Schubert M, et al. | Int J Environ Res Public Health
Aim: To quantify the isolated effect of age on severe COVID-19 outcomes
CLINICAL CHARACTERISTICS
8/23/20
Murphy RP, Dennehy KA, Costello MM, et al. | Age Ageing
Aim: To describe the satisfaction, clinic productivity, clinical benefit, satisfaction and costs associated with the virtual geriatric clinic model of care.
INFECTION CONTROL
8/21/20
Karlsen APH, Wiberg S, Laigaard J, et al. | PLoS One
Aim: To provide a global snapshot overview of interventions and main methodological aspects of planned and initiated randomised clinical trials on COVID-19 prevention and treatment. 
CANDIDATE THERAPEUTICS
8/21/20
Lechien JR, Radulesco T, Calvo-Henriquez C, et al. | Head Neck Pathol
Aim: To review the data regarding the expression of angiotensin converting enzyme-2 (ACE2) and transmembrane protease serine-2 (TMPRSS2) in head and neck tissue.
8/21/20
Taneri PE, Ochoa S, Llanaj E, et al. | Eur J Epidemiol
Aim: To evaluate biomarkers of anemia and iron metabolism (hemoglobin, ferritin, transferrin, soluble transferrin receptor, hepcidin, haptoglobin, unsaturated iron-binding capacity, erythropoietin, free erythrocyte protoporphyrine, and prevalence of anemia) in patients diagnosed with COVID-19, and explore their prognostic value. 
UPDATED
CLINICAL CHARACTERISTICS
8/21/20
Turan O, Hakim A, Dashraath P, et al. | Int J Gynaecol Obstet
Aim: To summarize clinical characteristics and outcomes among pregnant women hospitalized with COVID-19.
CLINICAL CHARACTERISTICS
8/21/20
Shang L, Shao M, Guo Q, et al. | Arch Med Res
Aim: To assess whether diabetes mellitus (DM) would increase the risk of severe infection and death in patients with COVID-19.
CLINICAL CHARACTERISTICS
8/21/20
 | Health Information and Quality Authority, Ireland
Aim: To review the evidence on the routine wearing of face masks by healthy persons in the community in reducing the transmission of respiratory pathogens.
8/21/20
Deshmukh V, Motwani R, Kumar A, et al. | J Clin Pathol
Aim: To review and summarise the latest histopathological changes in different organs observed after autopsy of COVID-19 cases.
CLINICAL CHARACTERISTICS
8/21/20
Pranata R, Huang I, Raharjo SB | Indian Pacing Electrophysiol J
Aim: To evaluate the incidence of cardiac arrhythmias in patients with COVID-19 and their implications on patient prognosis.
CLINICAL CHARACTERISTICS
8/21/20
Talaie H, Hosseini SM, Nazari M, et al. | Daru
Aim: To synthesize the results of well-done observational studies and clinical trials to estimate the value of some clinical managements to confront COVID-19.
CANDIDATE THERAPEUTICS
8/21/20
Khalili MA, Leisegang K, Majzoub A, et al. | World J Mens Health
Aim: To investigate the current evidence of SARS-CoV-2 impact on male reproduction and pregnancy outcomes, discussing them in light of the evidence published on other coronaviruses.
CLINICAL CHARACTERISTICS
8/21/20
Abdel-Maboud M, Menshawy A, Elgebaly A, et al. | J Thromb Thrombolysis
Aim: To investigate whether prophylactic heparin use is associated with reduction in thromboembolic events. 
CANDIDATE THERAPEUTICS
8/20/20
Misra S, Nath M, Hadda V, et al. | Eur J Clin Invest
Aim: To assess the efficacy of various treatment modalities in nCOV-2019 patients.
CANDIDATE THERAPEUTICS
8/20/20
 | Public Health Agency of Canada
Aim: Not provided
8/20/20
Mahumud RA, Kamara JK, Renzaho AMN | Infection
Aim: To examine the overall distribution of chronic comorbidities in coronavirus disease-19 (COVID-19) infected populations and the risk of the underlying burden of disease in terms of the case fatality ratio (CFR).
CLINICAL CHARACTERISTICS
8/19/20
Selman L, Lapwood S, Jones N, et al. | Oxford COVID-19 Evidence Service
Aim: To review the evidence on advance care planning in community settings during the COVID-19 pandemic.
8/19/20
Remillard L, Perras C, Pant S, et al. | CADTH
Aim: To review the current scientific evidence on the potential benefits and harms of chloroquine and hydroxychloroquine for the prevention or treatment of COVID-19. 
8/19/20
Ortolan A, Lorenzin M, Felicetti M, et al. | Int J Infect Dis
Aim: To analyse the influence of gender on COVID-19 mortality, severity and disease outcomes. 
CLINICAL CHARACTERISTICS
8/19/20
 | Public Health Agency of Canada
8/19/20
 | Public Health Agency of Canada
Aim: To review the evidence on the difference in risk of transmission from persons who are pre- and asymptomatic infected cases compared to symptomatic cases?
8/19/20
 | Public Health Agency of Canada
Aim: To examine the evidence on whether pregnant women at higher risk of severe COVID-19 disease than non-pregnant women of reproductive age.
8/19/20
 | Public Health Agency of Canada
Aim: To review the evidence on the impact of physical distancing of 1 meter, 1.5 meters and 2 meters on SARS-CoV-2 virus transmission risk.
8/19/20
 | Public Health Agency of Canada
8/19/20
Kumar D, Spry C | CADTH
Aim: To review the evidence on the effectiveness of face shields at preventing SARS-CoV-2 virus transmission.
8/19/20
Elsawah H, Elsokary MA, Elrazzaz M, et al. | J Med Virol
Aim: To assess the evidence strength of hydroxychloroquine efficacy in treating COVID-19 arising from clinical trials and to update the practice with the most reliable clinical evidence.
CANDIDATE THERAPEUTICS
8/19/20
Xiong J, Lipsitz O, Nasri F, et al. | J Affect Disord
Aim: To synthesize extant literature that reports on the effects of COVID-19 on psychological outcomes of the general population and its associated risk factors.
MENTAL HEALTH
8/19/20
McAloon C, Collins A, Barber A, et al. | BMJ Open
Aim: To conduct a rapid systematic review and meta-analysis of estimates of the incubation period of COVID-19.
CLINICAL CHARACTERISTICS
8/19/20
Guentcheva I | Centre de Recherche en Sante Publique
Aim: To review the effectiveness of the obligation to wear a mask in a population without concrete social acceptability measures having been deployed beforehand.
8/19/20
Chtourou H, Trabelsi K, H'Mida C, et al. | Front Psychol
Aim: To summarize the existing literature regarding the effect of quarantine and social distancing on psychology and well-being, while providing possible practical recommendations for being more physically active during isolation periods.
MENTAL HEALTH
8/19/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the effectiveness of wearing a surgical mask at the same time as an oxygen mask.
8/19/20
Topfer L | CADTH
Aim: To identify a list of potential technologies that may be used to address the negative effects of social isolation on older adults living in long-term care.
8/19/20
Luo X, Ni X, Lin J, et al. | Phytomedicine
Aim: To investigate the efficacy and safety of CHM or CHM combination therapy for COVID-19.
CANDIDATE THERAPEUTICS
8/19/20
Vaja R, chan J, Ferreira P, et al. | Br J Clin Pharmacol
Aim: To evaluate cardiovascular and respiratory complications in patients taking NSAIDs during acute lower respiratory tract infections.
CLINICAL CHARACTERISTICS
8/19/20
Birkeland K, Zimmer R, Kimchi A, et al. | Interact J Med Res
Aim: To estimate VTE incidence in hospitalized patients and to analyze characteristic factors in the VTE cohort.
CLINICAL CHARACTERISTICS
8/17/20
Inomata T, Kitazawa K, Kuno T, et al. | Invest Ophthalmol Vis Sci
Aim: To determine currently reported clinical and prodromal ocular symptoms in patients with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
8/17/20
Labenz C, Toenges G, Worns M, et al. | Eur J Gastroenterol Hepatol
Aim: To review the evidence on published data on liver injury in patients with COVID-19 infection.
CLINICAL CHARACTERISTICS
8/17/20
Dubey P, Reddy SY, Manuel S, et al. | Eur J Obstet Gynecol Reprod Biol
Aim: To estimate the adverse maternal and neonatal characteristics and outcomes among COVID-19 infected women and determine heterogeneity in the estimates and associated factors.
CLINICAL CHARACTERISTICS
8/17/20
Thomson DJ, Yom SS, Saeed H, et al. | Int J Radiat Oncol Biol Phys
Aim: To aggregate changes in the quality of the evidence supporting these schedules to establish a comprehensive evidence base for future reference and highlight aspects for future study.
INFECTION CONTROL
8/16/20
Hessami K, Homayoon N, Hashemi A, et al. | J Matern Fetal Neonatal Med
Aim: To review the evidence regarding maternal, fetal and neonatal mortality cases associated with COVID-19 infection.
CLINICAL CHARACTERISTICS
8/15/20
Fan AF, Gu S, Alemi AF, et al. | J Integr Med
Aim: To summarize contemporary studies that report the use of Chinese herbal medicine (CHM) to treat COVID-19.
CANDIDATE THERAPEUTICS
8/15/20
Nasiri MJ, Haddadi S, Tahvildari A, et al.  | Front Med
Aim: To better understand role of the sex in mortality of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
8/15/20
Rakedzon S, Khoury Y, Rozenberg G, et al. | Rambam Maimonides Med J
Aim: To review the existing clinical evidence of HCQ use for the prevention and treatment of COVID-19.
CANDIDATE THERAPEUTICS
8/15/20
Lv H, Chen T, Pan Y, et al. | Ann Transl Med
Aim: To estimate the prevalence and identify the underlying differential diagnostic value of VES.
DIAGNOSTICS
8/15/20
Boregowda U, Aloysius M, Perisetti A, et al. | Front Med
Aim: To compare the serum liver chemistries such as hepatic transaminases, total bilirubin, albumin, and prothrombin time to evaluate whether they can predict severity and mortality in COVID-19.
CLINICAL CHARACTERISTICS
8/14/20
Knisely A, Wu J, Kaplan SJ, et al. | Cancer Invest
Aim: To examine the patterns of clinical presentations and outcomes in patients with cancer with coronavirus-spectrum illness to offer guidance on detection and management of COVID-19 disease in this particularly susceptible cohort of patients.
CLINICAL CHARACTERISTICS
8/14/20
Manchanda ECC, Sanky C, Appel JM | J Racial Ethn Health Disparities
Aim: To identify and review all publicly available state-level CSC in the USA and to compare the ways in which CSC prioritize patients for the allocation of scarce resources such as ventilators, and to consider the ethical and equity implications of these decisions.
8/14/20
de Moura DTH, McCarty TR, Ribeiro IB, et al. | Clinics (Sao Paulo)
Aim: To perform a structured systematic review and meta-analysis to evaluate the diagnostic characteristics of serological-based COVID-19 testing.
UPDATED
DIAGNOSTICS
8/14/20
Li J, Huang DQ, Zou B, et al. | J Med Virol
Aim: To determine pooled estimates for clinical characteristics and outcomes in COVID-19 patients including subgroups by disease severity (based on WHO Interim Guidance Report or IDSA/ATS criteria) and by country/region.
CLINICAL CHARACTERISTICS
8/14/20
Luo W, Sun J, Zhang W, et al. | BMJ Open
Aim: To determine the quality of recommendations for optimising management in paediatric wards and provide suggestions to hospital managers for the adjustment of existing hospital prevention and control strategies, and also to offer recommendations for further research.
INFECTION CONTROL
8/12/20
Davalbhakta S, Advani S, Kumar S, et al. | J Med Syst
Aim: To provide an overview of mobile applications being currently utilized for COVID-19 related activities.
UPDATED
INFECTION CONTROL
8/12/20
Samanta A, Shetty A, Nelson PC | J Telemed Telecare
Aim: To conduct a systematic literature review of the accuracy and effectiveness of available portable automated refractors compared to the current standard of care, subjective refraction (SR).
INFECTION CONTROL
8/12/20
Moosavi SA, Mashhadiagha A, Hashemazar A, et al. | Transpl Infect Dis
Aim: to conduct a systematic review on COVID?19 clinical manifestations and treatment strategies in SOT recipients.
UPDATED
CLINICAL CHARACTERISTICS
8/12/20
Kasperkiewicz M | J Am Acad Dermatol
Aim: To review the evidence on how the COVID-19 pandemic affects patients with autoimmune bullous diseases.
CLINICAL CHARACTERISTICS
8/12/20
Kow CS, Hasan SS | Am J Cardiol
Aim: To summarise the existing evidence on the effect of statins on the clinical outcomes of COVID-19 from adjusted analyses.
CANDIDATE THERAPEUTICS
8/11/20
Sarkar S, Soni KD, Khanna P | J Med Virol
Aim: To evaluate the impact of CPT in COVID-19 patients based on the publications reported to date.
CANDIDATE THERAPEUTICS
8/11/20
Almutairi A, Alfaleh M, Alasheikh M | Cureus
Aim: To evaluate the medical literature and explore the dermatological clinical manifestations in patients with SARS-CoV-2.
CLINICAL CHARACTERISTICS
8/11/20
Jain VK, Lal H, Patralekh MT, et al. | J Clin Orthop Trauma
Aim: To evaluate the fracture types, presentation, treatment, complications, and early outcomes of fractures occurring amidst COVID-19 pandemic.
INFECTION CONTROL
8/11/20
Jones L, Candy B, Roberts N, Ondruskova T, et al | Oxford COVID-19 Evidence Service Team
Aim: To review the evidence on the management of delirium in patients with COVID-19 and the use of non-pharmacological approaches outside of critical care settings.
UPDATED
8/11/20
Katal S, Johnston SK, Johnston JH, et al. | Acad Radiol
Aim: To review the radiological characteristics of COVID-19 in pediatrics.
CLINICAL CHARACTERISTICS
8/11/20
Mahendiratta S, Batra G, Sarma P, et al. | Life Sci
Aim: To evaluate the effectiveness of the molecular detection techniques in COVID-19. 
INFECTION CONTROL
8/11/20
Robbins-Jaurez SY, Qian L, King KL, et al. | Kidney Int Rep
Aim: To assess the incidence of AKI among patients with COVID-19 and examine their associations with patient outcomes as reported in the available literature thus far.
CLINICAL CHARACTERISTICS
8/11/20
da Silva FCT, Neto MLR | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To review the evidence on the psychiatric repercussions in health professionals that work in health systems to fight the clinical implications caused by COVID-19.
MENTAL HEALTH
8/11/20
da Silva FCT, Neto MLR | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To analyze the main psychological effects caused by the COVID-19 pandemic in health professionals.
MENTAL HEALTH
8/11/20
Sheraton M, Deo N, Dutt T, et al. | Psychiatry Res
Aim: To compare the incidences of psychological issues during the COVID-19 pandemic, such as anxiety, depression, occupational stress, PTSD and insomnia, in healthcare workers (HCW) and non-healthcare workers (NHCW). 
MENTAL HEALTH
8/11/20
Chen C, Pan K, Wu B, et al. | Eur J Clin Pharmacol
Aim: To evaluate the safety of HCQ in the treatment of COVID-19 and other diseases by performing a systematic review and meta-analysis.
8/11/20
D'Amico F, Danese S, Peyrin-Biroulet L | Clin Gastroenterol Hepatol
Aim: To investigate symptoms and diagnostic-therapeutic management of IBD patients with COVID-19.
CLINICAL CHARACTERISTICS
8/11/20
Licina A, Silvers A, Stuart RL  | Syst Rev
Aim: To evaluate the effect of powered air-purifying respirators (PAPRs) as part of respiratory protection versus another device (egN95/FFP2) on HCW infection rates and contamination.
UPDATED
8/10/20
Pettirosso E, Giles M, Cole S, et al. | Aust N Z J Obstet Gynaecol
Aim: To describe the current understanding of COVID?19 illness in pregnant women, to describe obstetric outcomes and to identify gaps in the existing knowledge.
CLINICAL CHARACTERISTICS
8/10/20
Abrams JY, Godfred-Cato SE, Oster ME, et al. | J Pediatr
Aim: To develop a more comprehensive description of multisystem inflammatory syndrome in children (MIS-C).
CLINICAL CHARACTERISTICS
8/9/20
Cui X, Zhao Z, Zhang T, et al. | J Med Virol
Aim: To provide a comprehensive and systematic analysis of demographic characteristics, clinical symptoms, laboratory findings and imaging features of coronavirus disease 2019 (COVID-19) in pediatric patients.
UPDATED
CLINICAL CHARACTERISTICS
8/9/20
Jutzeler CR, Bourguignon L, Weis CV, et al. | Travel Med Infect Dis
Aim: To gather all available information regarding comorbidities, clinical signs and symptoms, outcomes, laboratory findings, imaging features, and treatments in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
8/9/20
Neumann-Podczaska A, Al-Saad SR, Karbowski LM, et al. | Aging Dis
Aim: To concisely summarize the clinical features, comorbidities, radiological/laboratory findings, and outcomes in the older adults. 
CLINICAL CHARACTERISTICS
8/9/20
Hoang A, Chorath K, Moreira A, et al. | EClinicalMedicine
Aim: To characterize clinical symptoms, laboratory, and imaging findings, as well as therapies provided to confirmed pediatric cases of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
8/9/20
Xu X, Shi Y, Wang R, et al. | Integr Med Res
Aim: To comprehensively summarize and analyze the current guidelines on home-based traditional Chinese medicine (TCM) nursing interventions for discharged patients with COVID-19.
CANDIDATE THERAPEUTICS
8/9/20
Wu T, Zuo Z, Deng M | Aging Dis
Aim: To provide systematic evidence for the association between multiorgan dysfunction and COVID-19 development.
UPDATED
CLINICAL CHARACTERISTICS
8/9/20
Cooke JE, Eirich R, Racine N, et al. | Psychiatry Res
Aim: To review the evidence on posttraumatic stress and general psychological stress symptoms during COVID-19.
MENTAL HEALTH
8/9/20
Samaranayake L, Fakhruddin K, Panduwawala C | Acta Odontol Scand
Aim: To evaluate the contemporary evidence on dysgeusia and anosmia as trigger prodromal symptoms, and their prevalence in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/9/20
Haider Z, Aweid B, Subramanian P, et al. | J Telemed Telecare
Aim: To explore evidence for telemedicine in orthopaedics to determine its advantages, validity, effectiveness and utilisation.
INFECTION CONTROL
8/9/20
Sanchez-Ramirez DC, Mackey D | Respir Med
Aim: To explore the association of underlying respiratory diseases and smoking with severe outcomes in patients with COVID-19 infection.
CLINICAL CHARACTERISTICS
8/9/20
Barochiner J, Martinez R | J Clin Pharm Ther
Aim: To compare the occurrence of severe and fatal COVID-19 in infected patients who were under treatment with angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) vs no treatment or other antihypertensives.
UPDATED
CANDIDATE THERAPEUTICS
8/9/20
Baladia E, Pizarro AB, Ortiz-Munoz L, et al. | Medwave
Aim: To provide a timely, rigorous, and continuously updated summary of the available evidence on the role of vitamin C in treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/7/20
Zheng B, Wang H, Yu C | Pediatr Pulmonol
Aim: To systematically review the current situation and public health burden associated with children infected with SARS-CoV2.
CLINICAL CHARACTERISTICS
8/7/20
Liu X, Long C, Ziong Q, et al. | Clin Cardiol
Aim: To review the current evidence and assess the clinical prognosis of COVID?19 patients with or without hypertension treated with ACEs/ARBs.
CANDIDATE THERAPEUTICS
8/7/20
Wu X, Liu L, Jiao J, et al. | Ann Med
Aim: To review the evidence on clinical, laboratory and imaging factors related to mild vs. severe COVID-19 infection.
CLINICAL CHARACTERISTICS
8/7/20
De Sanctis P, Doneddu PE, Vigano L, et al. | Eur J Neurol
Aim: To identify specific clinical features of GBS associated with COVID-19.
CLINICAL CHARACTERISTICS
8/7/20
Salunke AA, Nandy K, Pathak PK, et al. | Diabetes Metab Syndr
Aim: To evaluate the impact of cancer on serious events including ICU admission rate and mortality in COVID 19.
CLINICAL CHARACTERISTICS
8/7/20
Sharifian-Dorche M, Huot P, Osherov M, et al. | J Neurol Sci
Aim: To review the neurological complications of CoV infection in humans.
CLINICAL CHARACTERISTICS
8/7/20
Chi G, Lee JJ, Jamil A, et al. | J Clin Med
Aim: To offer benchmark data on the incidence of VTE and to examine the difference in D-dimer levels among anticoagulated COVID-19 patients with and without VTE incident. 
UPDATED
CANDIDATE THERAPEUTICS
8/6/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the extended use or re-use of personal protective equipment (PPE) during COVID-19.
UPDATED
8/6/20
Tariq R, Saha S, Furqan F, et al. | Mayo Clin Proc
Aim: To evaluate the prevalence of gastrointestinal (GI) symptoms and mortality in patients with coronavirus disease 2019 (COVID-19) diagnosed.
8/6/20
Agyeman AA, Chin KL, Landersdorfer CB, et al. | Mayo Clin Proc
Aim: To estimate the prevalence of olfactory and gustatory dysfunctions (OGDs) among patients infected with novel coronavirus disease 2019 (COVID-19).
8/5/20
Kariyanna PT, Sutarjono B, Grewal E, et al. | Am J Med Case Rep
Aim: To identify the clinical features of myocarditis in COVID-19 patients.
8/5/20
Pei L, Zhang S, Huang L, et al. | Pol Arch Intern Med
Aim: To evaluate the impact of drug therapy on the risk of death in patients with COVID-19.
8/5/20
 | Public Health Agency of Canada
Aim: To review the evidence for age-dependent transmission of SARS-CoV-2.
8/5/20
Kumar A, Arora A, Sharma P, et al. | Indian J Gastroenterol
Aim: To determine the frequency of GI and hepatic manifestations of COVID-19 and to explore their relationship with severe clinical course.
UPDATED
8/5/20
Ghahramani S, Tabrizi R, Lankarani KB, et al. | Eur J Med Res
Aim: To understand the common laboratory features of COVID-19 in severe cases versus non-severe patients could be quite useful for clinicians and might help to predict the model of disease progression.
UPDATED
8/5/20
Reddy RK, Charles WN, Sklavounos A, et al. | J Med Virol
Aim: To rigorously and definitively quantify the effects of smoking on COVID-19 severity.
UPDATED
8/5/20
Mansourabadi AH, Sadeghalvad M, Mohammadi-Motlagh H, et al. | Life Sci
Aim: To describe the role of the immune system in response to COVID-19.
8/5/20
Desiato VM, Levy DA, Byun YJ, et al. | Am J Rhinol Allergy
Aim: To perform a systematic review and meta-analysis of the prevalence of OD in the healthy general population, review the various assessment metrics used, and compare pooled OD prevalence rates.
8/5/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the symptoms and incidence for vascular events in patients with COVID-19.
8/5/20
Hasan SS, Radford S, Kow CS, et al. | J Thromb Thrombolysis
Aim: To systematically review the available evidence to help guide clinicians weighing up decisions regarding the anticoagulation approach for COVID-19 patients admitted to intensive care units.
8/4/20
Gao Y, Ye L, Zhang J, et al. | BMC Infect Dis
Aim: To systematically review the clinical features and outcomes of pregnant women with COVID-19.
UPDATED
8/4/20
Yoon SH, Kang J, Ahn JG | Eur Rev Med Pharmacol Sci
Aim: To evaluate the clinical manifestations and outcomes of neonates born to women who had Coronavirus Disease 2019 (COVID-19) during pregnancy.
8/4/20
Kay JK, Parsel SM, Marsh JJ, et al. | JAMA Otolaryngol Head Neck Surg
Aim: To review evidence on the risks of aerosolization and transmission of SARS-CoV-2 from patients to health care personnel during endoscopy of the upper aerodigestive tract.
8/4/20
Elgohary G | Hematol Oncol Stem Cell Ther
Aim: To evaluate the impact of COVID-19 infection on cancer patients. 
8/4/20
Khan S, Gionfriddo MR, Cortes-Penfield N, et al. | Expert Opin Pharmacother
Aim: To synthesize the literature on COVID-19 pharmacotherapy to inform practice and policymaking.
8/3/20
Shao M, Li X, Liu F, et al. | Pharmacol Res
Aim: To investigate whether the presence of acute kidney injury (AKI) might increase the risk of severe infection and fatality in COVID-19 patients.
CLINICAL CHARACTERISTICS
8/3/20
Putman M, Chock YPE, Tam H, et al. | Arthritis Rheumatol
Aim: To identify and summarize research that describes the use of antirheumatic disease therapies for the treatment of COVID-19.
CANDIDATE THERAPEUTICS
8/3/20
Wu B, Gu D, Yu J, et al. | Infect Genet Evol
Aim: To delve into the association between ABO blood group and COVID-19 infection, severity and demise.
CLINICAL CHARACTERISTICS
8/3/20
Sales-Peres SHC, de Azevedo-Silva LJ, Bonato RCS, et al. | Obes Res Clin Pract
Aim: To investigate the relationship between coronavirus disease 2019 (COVID-19) and obesity in critically ill patients admitted to the intensive care unit (ICU).
UPDATED
CLINICAL CHARACTERISTICS
8/3/20
Carlo D, Montemurro N, Petrella G, et al. | J Neurol
Aim: To review the evidence on the spectrum of neurological symptoms experienced by COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/3/20
Zuin M, Rigatelli G, Zuliani G, et al. | J Cardiovasc Med
Aim: To investigate the relationship between ACI and mortality risk in COVID-19 patients.
CLINICAL CHARACTERISTICS
8/3/20
Rocke J, Hopkins C, Philpott C, et al. | Clin Otolaryngol
Aim: To systematically review the currently available evidence investigating the association between olfactory dysfunction (OD) and the novel coronavirus (COVID-19).
CLINICAL CHARACTERISTICS
8/3/20
Kotlyar A, Grechukihina O, Chen A, et al | Am J Obstet Gynecol
Aim: To determine estimates of vertical transmission of COVID-19 based upon early RNA detection of SARS-CoV-2 after birth from various neonatal/fetal sources and neonatal serology.
CLINICAL CHARACTERISTICS
8/2/20
Sahu AK, Amrithanand VT, Mathew R, et al. | Am J Emerg Med
Aim: To determine the proportion of HCW who were COVID-19 positive among all the COVID-19 patients. 
8/2/20
de Siqueira JVV, Almeida LG, Zico BO | Obes Res Clin Pract
Aim: To assess whether there was an association between obesity and higher levels of hospitalization, poor outcomes and mortality due to the disease of novel coronavirus (COVID-19).
CLINICAL CHARACTERISTICS
8/2/20
Rooney S, Webster A, Paul L | Phys Ther
Aim: To 1) compare physical function and fitness outcomes in people infected with SARS-CoV to healthy controls; 2) quantify the recovery of physical function and fitness following SARS-CoV infection; 3) determine the effects of exercise following SARS-CoV infection.
CLINICAL CHARACTERISTICS
8/2/20
Volpe M, Battistoni A | Int J Cardiol
Aim: To review the evidence on the potential role of renin-angiotensin system inhibitors, specifically angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, with regard to COVID-19 disease and mortality.
CANDIDATE THERAPEUTICS
8/2/20
Harrop E, Mann M, Semedo L, et al. | Palliat Med
Aim: To synthesise the evidence regarding system-level responses to mass bereavement events, including natural and human-made disasters as well as pandemics, to inform service provision and policy during the COVID-19 pandemic and beyond.
8/1/20
Qiu P, Zhou Y, Wang F, et al. | Aging Clin Exp Res
Aim: To find risk factors for the COVID-19-related death, helping to enhance the efficacy and reduce the mortality of COVID-19.
CLINICAL CHARACTERISTICS
8/1/20
Awulachew E, Diriba K, Anja A, et al. | Radiol Res Pract
Aim: To systematically analyze the existing literature on CT imaging features of patients with COVID-19 pneumonia.
CLINICAL CHARACTERISTICS
8/1/20
Mirzaei H, McFarland W, Karamouzian M, et al. | AIDS Behav
Aim: To review the evidence on the earliest patients with COVID-19-HIV co-infection.
CLINICAL CHARACTERISTICS
8/1/20
Pranata R, Soeroto AY, Huang I, et al. | Int J Tuberc Lung Dis
Aim: To investigate the association between chronic obstructive pulmonary disease (COPD) and smoking with outcome in patients with COVID-19.
CLINICAL CHARACTERISTICS
8/1/20
Hasan SS, Capstick T, Ahmed R, et al. | Expert Rev Respair Med
Aim: To review ARDS-associated mortality and the potential role of systemic corticosteroids in COVID-19 patients.
CANDIDATE THERAPEUTICS
8/1/20
Baradaran A, Ebrahimzadeh MH, Baradaran A, et al. | Arch Bone Jt Surg
Aim: To assess the prevalence of comorbidities in the confirmed COVID-19 patients.
CLINICAL CHARACTERISTICS
8/1/20
Liu H, Gai S, Wang X et al. | Cardiovasc Res
Aim: To analyse ACE2 and SARS-CoV-2 spike (S) protein proteases at the single-cell level, to explore the cardiac involvement in COVID-19 and improve our understanding of the potential cardiovascular implications of COVID-19.
CLINICAL CHARACTERISTICS
8/1/20
Akbari H, Tabrizi R, Lankarani KB, et al. | Life Sci
Aim: To make a comparison between the clinical laboratory-related factors, complete blood count (CBC) indices, cytokines, and lymphocyte subsets in order to distinguish severe coronavirus disease 2019 (COVID-19) cases from the non-severe ones.
UPDATED
CLINICAL CHARACTERISTICS
8/1/20
Monaghesh E, Hajizadeh A | BMC Public Health
Aim: To identify the role of telehealth services during COVID-19 outbreak.
UPDATED
INFECTION CONTROL
8/1/20
Zhang L, Peres TG, Silva MVF et al. | Pediatr Pulmonol
Aim: To summarize what we know so far about coronavirus disease (COVID?19) in children.
CLINICAL CHARACTERISTICS
7/31/20
Akhtar H, Patel C, Abuelgasim E, et al. | Gynecol Obstet Invest
Aim: To review published studies related to the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections with pregnancy, foetal, and neonatal outcomes during coronavirus disease 2019 (COVID-19) pandemic.
CLINICAL CHARACTERISTICS
7/31/20
Clark EG, Hiremath S, Soroka SD, et al. | Can J Kidney Health Dis
Aim: To synthesize guidance documents from the broader nephrology community in an effort to provide the best possible care to the largest number of patients with kidney disease while also ensuring the safety of the health care team.
INFECTION CONTROL
7/31/20
Seresirikachorn K, Phoophiboon V, Chobarporn T, et al. | Infect Control Hosp Epidemiol
Aim: To evaluate the effectiveness of existing decontamination methods of surgical masks and N95 FFRs and provide evidence-based recommendations for selecting an appropriate decontamination method.
INFECTION CONTROL
7/31/20
Tng XJJ, Chew QH, Sim K | Singapore Med J
Aim: To examine and summarise existing studies to date regarding the psychological impact of COVID-19 on various populations.
MENTAL HEALTH
7/31/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on how long the virus can survive with potential for infection on surfaces.
UPDATED
7/31/20
Mitchell S, Maynard V, Lyons V, et al | Palliat Med
Aim: To synthesise existing evidence related to the delivery of palliative and end-of-life care by primary healthcare professionals in epidemics and pandemics.
UPDATED
7/30/20
Zhou Y, Yang Q, Chi J, et al. | Int J Infect Dis
Aim: To evaluate the association between different comorbidities and the severity of Covid-19.
CLINICAL CHARACTERISTICS
7/30/20
Hadeler E, Gitlow H, Nouri K | Arch Dermatol Res
Aim: To evaluate recent studies that have analyzed patient satisfaction with teledermatology. 
7/30/20
Figliozzi S, Masci P, Ahmadi N, et al. | Eur J Clin Invest
Aim: To review available evidence and provide pooled estimates on predictors of clinical outcomes in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/30/20
Musa A, Pendi K, Hashemi A, et al. | West J Emerg Med
Aim: To review the evidence on the use of remdesivir for the treatment of COVID-19.
CANDIDATE THERAPEUTICS
7/30/20
Shah K, Saxena D, Mavalankar D | QJM
Aim: To assess global statistics and characteristics of household secondary attack rate (SAR) of COVID-19.
INFECTION CONTROL
7/29/20
Yasuhara J, Kuno T, Takagi H, et al. | Pediatr Pulmonol
Aim: To investigate the clinical characteristics of COVID-19 in children.
CLINICAL CHARACTERISTICS
7/29/20
Chakravarti A, Upadhyay S, Bharara T, et al. | Indian J Med Microbiol
Aim: To provide an insight about the current understanding, knowledge gaps and a perspective on the future of coronavirus disease 2019 (COVID-19) infections. 
7/29/20
Liao S, Shao S, Chen Y, et al. | Crit Care
Aim: To review the evidence on severe complications of COVID-19 associated with coagulation changes, mainly characterized by increased D-dimer and fibrinogen levels with higher thrombosis risk, in particular pulmonary embolism (PE).
CLINICAL CHARACTERISTICS
7/29/20
Shulte PA, Streit JMK, Sheriff F, et al. | Ann Work Expo Health
Aim: To identify and characterize scenarios and hazards in the future of work after a global pandemic.
7/28/20
Rao SN, Manissero D, Steele VR, et al. | Infect Dis Ther
Aim: To review available knowledge on correlations between SARS-COV-2 Ct values and patient- or healthcare-related outcomes to determine whether Ct values provide useful clinical information.
CLINICAL CHARACTERISTICS
7/28/20
Langford B, So M, Raybardhan S, et al. | Clin Microbiol Infect
Aim: To determine the prevalence of bacterial co-infection (at presentation) and secondary infection (after presentation) in patients with COVID-19.
CLINICAL CHARACTERISTICS
7/28/20
Li X, Pan X, Li Y, et al. | Crit Care
Aim: To comprehensively evaluate the impact of cardiac injury and its related biomarkers on mortality and other prognosis in patients infected with SARS-CoV-2.
CLINICAL CHARACTERISTICS
7/28/20
Capobianco G, Saderi L, Aliberti S, et al. | Eur J Obstet Gynecol Reprod Biol
Aim: To assess the risk of clinical complications in pregnant women and neonates infected with SARS-CoV-2.
CLINICAL CHARACTERISTICS
7/28/20
Abdi A, Jalilian M, Sarbarzeh PA, et al. | Diabetes Res Clin Pract
Aim: To summarize the evidence about diabetes and COVID-19 outbreak through a systematic review and meta-analysis approach.
CLINICAL CHARACTERISTICS
7/28/20
Jin X, Chua HZ, Wang K, et al. | Integr Med Res
Aim: To summarize all the clinical studies to generate reliable evidence for decision-making on the medicinal value of Squama Manitis.
CANDIDATE THERAPEUTICS
7/28/20
Malik VS, Ravindra K, Attri SV, et al. | Environ Sci Pollut Res Int
Aim: To examine the emerging evidence to identify an association between body mass index (BMI) and COVID-19 disease outcome.
CLINICAL CHARACTERISTICS
7/28/20
Wu Y, Li H, Guo X, et al. | Hepatol Int
Aim: To explore the incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 patients.
CLINICAL CHARACTERISTICS
7/28/20
Kovalic AJ, Satapathy SK, Thuluvath PJ | Hepatol Int
Aim: To determine the prevalence of CLD in patients with COVID-19 and their clinical outcomes.
CLINICAL CHARACTERISTICS
7/28/20
Cortegiani A, Ippolito M, Greco M, et al. | Pulmonology
Aim: To describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy. and safety.
CANDIDATE THERAPEUTICS
7/28/20
Haiduc AA, Alom S, Melamed N, Harky A | J Card Surg
Aim:  To examine the literature evidence behind using extracorporeal membrane oxygenation in COVID?19 patients in a systematic review manner.
CANDIDATE THERAPEUTICS
7/28/20
Radulesco T, Lechien JR, Sowerby L, et al. | Eur Arch Otorhinolaryngol
Aim: To summarize recommendations for sinus and anterior skull base surgery during the COVID-19 pandemic.
UPDATED
INFECTION CONTROL
7/28/20
Weiss A, Jellingso M, Sommer MOA | EBioMedicine
Aim: To conduct a coherent overview of the duration of viral detection and viral RNA load in COVID-19 patients, stratified by specimen type, clinical severity, and age.
CLINICAL CHARACTERISTICS
7/28/20
Lan S, Lai C, Huang H, et al. | Int J Antimicrob Agents
Aim: To assess the efficacy of tocilizumab for the treatment of severe coronavirus disease-2019 (COVID-19).
CANDIDATE THERAPEUTICS
7/27/20
Cabrera-Tasayco FDP, Rivera-Carhuavilca JM, Atoche-Socola KJ, et al. | Disaster Med Public Health Prep
Aim: To determine biosecurity measures at the dental office after the appearance of COVID-19.
INFECTION CONTROL
7/27/20
Bwire GM, Majigo MV, Nijiro BJ, et al. | J Med Virol
Aim: To profile the positive detection rate from different clinical specimens using PCR to guide the selection of specimens for clinical diagnosis of COVID-19.
UPDATED
DIAGNOSTICS
7/27/20
Elsner P | J of the German Society of Derm
Aim: To answer the questions i) to which extent teledermatological procedures were used by dermatologists in the course of the COVID?19 pandemic and ii) which experiences with the application of teledermatological procedures in dermatological practices and clinics were reported in the literature
INFECTION CONTROL
7/25/20
Solis-Garcia Del Pozo J, Galindo MF, Nava E, et al. | Eur Rev Med Pharmacol Sci
Aim: To review the evidence on the role of IL-6 in treating COVID-19.
CANDIDATE THERAPEUTICS
7/25/20
Racine N, Cooke JE, Eirich R, et al. | Psychiatry Res
Aim: To conduct a rapid review of child and adolescent anxiety, depression, and traumatic stress experienced during the COVID-19 pandemic. 
MENTAL HEALTH
7/25/20
Rahman J, Mumin J, Fakhruddin B | Ann Glob Health
Aim: To appraise the frequency of T-zone (eyes, nose, mouth, chin) touching in humans to comprehend the challenge of its restriction, and thus support public health professionals to produce evidence synthesis guidance for public.
INFECTION CONTROL
7/25/20
Imran N, Aamer I, Sharif MI, et al. | Pak J Med Sci
Aim: To examine the impact of quarantine on mental health of children and adolescents, and proposes measures to improve psychological outcomes of isolation.
MENTAL HEALTH
7/25/20
Katims AB, Razdan S, Eilender BM, et al. | Urol Oncol
Aim: To provide a review of high-risk urologic cancers and the feasibility of delaying surgery without impacting oncologic or mortality outcomes.
INFECTION CONTROL
7/24/20
Lin J, Yan H, Chen H, et al. | J Med Virol
Aim: To review the blood coagulation indicators in severe COVID?19 patients.
CLINICAL CHARACTERISTICS
7/24/20
PHAC Emerging Science Group, Public Health Agency of Canada  | Public Health Agency of Canada
Aim: To review the evidence on the effectiveness of face shields at preventing SARS-CoV-2 virus transmission, with and without additional mask wearing.
7/24/20
PHAC Emerging Science Group, Public Health Agency of Canada  | Public Health Agency of Canada
Aim: To review the evidence on the aerodynamic properties of SARS-CoV-2 virus and travel distance, and the implications on transmission risk.
7/24/20
Venkatesulu BP, Chandrasekar VT, Giridhar P, et al. | J Med Virol
Aim: To do a systematic review and critical appraisal of the ongoing clinical trials that are assessing various therapeutic interventions against SARS-CoV-2 with an aim to provide insight into the various interventions tested, clinical rationale, geographical distribution of the trials as well as the endpoints assessed in the studies.
UPDATED
CANDIDATE THERAPEUTICS
7/24/20
 | Sante Publique France
7/24/20
 | Sante Publique France
7/23/20
de Melo GC, de Araujo KCGM | Cad Saude Publica
Aim: To analyze whether COVID-19 in pregnant women is related to premature birth and birth weight, and to summarize the diagnostic results of neonates born to mothers with COVID-19 for investigating the possibility of vertical transmission.
CLINICAL CHARACTERISTICS
7/23/20
James HK, Pattison GTR | J Surg Educ
Aim: To synthesise the current evidence of pandemic-related impact on surgical training internationally and describe strategies that have been put in place to mitigate disruption.
7/23/20
 | Public Health Agency of Canada
Aim: To review the evidence on determinants of individual adherence to public health interventions to prevent COVID-19.
7/23/20
Garcia-Iglesias JJ, Gomez-Salgado J, Martin-Pereira J, et al. | Rev Esp Salud Publica
Aim: To analyze the impact of the SARS-CoV-2 outbreak on healthcare professionals' mental health.
MENTAL HEALTH
7/23/20
Taherifard E, Taherifard E | Neurol Res
Aim: To systematically review the neurological complications in patients with SARS-CoV-2 infection and the methods used to diagnose both neurological complications and coronavirus infection.
CLINICAL CHARACTERISTICS
7/23/20
Deniz M, Tezer H | J Matern Fetal Neonatal Med
Aim: To review the current evidence on the vertical transmission of SARS CoV-2.
CLINICAL CHARACTERISTICS
7/22/20
Chen X, Laurent S, Onur OA, et al. | J Neurol
Aim: To study the frequency of neurological symptoms and complications in COVID-19 patients in a systematic review of the literature.
CLINICAL CHARACTERISTICS
7/22/20
Patterson TJ, Currie PJ, Beck J, et al. | Surgeon
Aim: To conduct an objective, systematic review of studies reporting on viral transmission risk comparing laparoscopic and open surgery.
INFECTION CONTROL
7/22/20
Sorrentino S, Cacia M, Leo I et al. | J Clin Med
Aim: To investigate whether the measurement of NT-proBNP may help discriminate clinical severity in patients with COVID-19
CLINICAL CHARACTERISTICS
7/22/20
PHAC Emerging Science Group, Public Health Agency of Canada  | Public Health Agency of Canada
Aim: To review the evidence on the de-escelation of "household bubbles" during the COVID-19 pandemic.
7/22/20
PHAC Emerging Science Group, Public Health Agency of Canada  | Public Health Agency of Canada
Aim: To review the evidence on the thresholds or allowable sizes of gatherings or events during the COVID-19 pandemic.
7/22/20
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the impact of the COVID-19 pandemic on families with children.
7/22/20
Bertrand K, Camire M, Milot D, et al. | University of Sherbrooke
Aim: To review the evidence on gender and sexual diversity in the adaptation of services in the context of the COVID-19 pandemic.
7/21/20
Ashraf MA, Keshavarz P, Hosseinpour P, et al. | J Reprod Infertil
Aim: To demonstrate the effects of COVID-19 on pregnant women and the possibility of vertical transmission.
CLINICAL CHARACTERISTICS
7/21/20
Vidali S, Morosetti D, Cossu E, et al. | ERJ Open Res
Aim: To highlight the correlation between elevated D-dimer (an indirect thrombosis marker) and the increased rate of poor prognosis-associated conditions, and to introduce D-dimer-labelled anticoagulant administration as a potentially useful tool to prevent complications and positively influence coronavirus disease 2019 (COVID-19) course.
CANDIDATE THERAPEUTICS
7/21/20
Kovalic AJ, Huang G, Thuluvath PJ, et al. | Hepatology
Aim: To further characterize liver injury and other unique clinical characteristics across COVID-19 severity.
CLINICAL CHARACTERISTICS
7/21/20
Lim MA, Pranata R, Huang I, et al. | Can J Kidney Health Dis
Aim: To investigate the association between several complications, including acute kidney injury (AKI), acute liver injury (ALI), and coagulopathy, with poor outcomes in COVID-19.
CLINICAL CHARACTERISTICS
7/21/20
He J, Guo Y, Mao R, et al. | J Med Virol
Aim: To systematically review the characteristics of asymptomatic infection in the coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
7/21/20
Kumar J, Meena J, Yadav A, et al. | J Trop Pediatr
Aim: To compile the radiological findings of COVID-19 pneumonia in children in a systematic manner.
CLINICAL CHARACTERISTICS
7/21/20
Wynants L, Van Calster B, Bonten MMJ | BMJ
Aim: To review and critically appraise published and preprint reports of models that aim to predict either (i) presence of existing COVID-19 infection, or (ii) future complications in individuals already diagnosed with COVID-19
UPDATED
7/21/20
Bajwa H, Riaz Y, Ammar M, et al. | Cureus
Aim: To analyze the published data on kidney injuries in COVID-19 and mortality rates in these patients.
CLINICAL CHARACTERISTICS
7/20/20
Cortegiani A, Ingoglia G, Ippolito M, et al. | J Crit Care
Aim: To evaluate the efficacy and safety of chloroquine and chloroquine-related formulations in patients with SARS-CoV-2 pneumonia and articles describing related in-vitro studies.
UPDATED
CANDIDATE THERAPEUTICS
7/20/20
Gao Y, Liu M, Chen Y, et al. | J Med Virol
Aim: To assess whether tuberculosis is associated with an increased risk of severe disease and death in patients with COVID-19.
CLINICAL CHARACTERISTICS
7/20/20
Egbert AR, Cankurtaran S, Karpiak S | Brain Behav Immun
Aim: To synthesize early data on typology and topography of brain abnormalities in adults with COVID-19 in acute/subacute phase.
CLINICAL CHARACTERISTICS
7/20/20
Tian Y, Qiu X, Wang C, et al. | Int J Cancer
Aim: To review the evidence on cancer prevalence in patients with COVID-19, and examine the association of cancer with severe events.
CLINICAL CHARACTERISTICS
7/20/20
Pei Y, Liu W, Masokano IB, et al. | J Infect Public Health
Aim: To investigate the differences in the clinical manifestations and imaging characteristics between Chinese children and adults with COVID-19 by systematically analyzing the data derived from some latest literatures.
CLINICAL CHARACTERISTICS
7/20/20
O'Hearn K, Gertsman S, Sampson M, et al. | J Hosp Infect
Aim: To synthesize existing data on the effectiveness of ultraviolet germicidal irradiation (UVGI) for N95 FFR decontamination.
INFECTION CONTROL
7/20/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy of face masks in helping to prevent the spread of COVID-19.
UPDATED
7/20/20
Noorimotlagh Z, Karami C, Mirzaee SA, et al. | Int Immunopharmacol
Aim: To help researchers to produce vaccine by collecting data for the control and prevention of SARS-CoV-2 and the immune and bioinformatic identification of T-cell and B-cell epitopes.
INFECTION CONTROL
7/20/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the risk of adverse post-operative outcomes on patients with COVID-19 or who have previously had COVID-19.
7/20/20
Eichberg DG, Basil GW, Di L, et al. | Neurosurgery
Aim: To conduct a systematic literature review investigating treatment of neurosurgical patients via telemedicine, and to evaluate barriers and challenges.
7/20/20
Shield KD, Chrystoja BR, Ali S, et al. | CMH Initiative
Aim: To review the evidence on how economic crises and natural disasters impact alcohol consumption and its harms.
MENTAL HEALTH
7/19/20
Pormohammad A, Ghorbani S, Baradaran B, et al. | Microb Pathog
Aim: To evaluate the clinical features and laboratory findings using a large sample size of COVID-19 infected patients in order to assist in its understanding, prevention and treatment.
UPDATED
CLINICAL CHARACTERISTICS
7/19/20
Zarifian A, Birdary MZ, Arekhi S, et al. | J Med Virol
Aim: To review the evidence on gastrointestinal and liver manifestations of COVID-19 patients.
CLINICAL CHARACTERISTICS
7/19/20
Chen Y, Shao S, Lai EC, et al. | Crit Care
Aim: To compare the mortality rate in patients with SARS, MERS, and COVID-19 who developed acute kidney injury.
CLINICAL CHARACTERISTICS
7/19/20
Abdullahi A, Candan SA, Abba MA, et al. | Front Neurol
Aim: To summarize the evidence on the neurological and musculoskeletal symptoms of the disease.
CLINICAL CHARACTERISTICS
7/19/20