COVID-19 Evidence Reviews
as of 5/14/21
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Today's Feature

5/12/2021
The New South Wales COVID-19 Critical Intelligence Unit provides rapid reviews that outline the available evidence on topics or questions related to the COVID-19 pandemic, with both grey and peer review literature included.



Completed Reviews
 
= living review
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
latest update
date
report
select
5/14/21
Biswas M, Most SKK | Sci Rep
Aim: To assess aggregated risk by investigating the association of ACEIs/ARBs users against non-users of ACEIs/ARBs with the risk of mortality or severe clinical manifestations or magnitude of SARS-CoV-2 test positivity in COVID-19 patients.
5/14/21
Soeroto AY, Purwiga A, Pranggono EH, et al. | Asian Pac J Allergy Immunol
Aim: To investigate the association between asthma and composite poor outcome in patients with coronavirus disease (COVID-19).
5/14/21
Wu T, Yu P, Li Y, et al. | J Asthma
Aim: To analyze the association between COVID-19 and asthma.
5/14/21
Antwi HA, Zhou L, Xu X, et al. | Healthcare
Aim: To examine the extent to which companies are able to balance their business interest with social interest through health-related CSR and how knowledge of them can help explain the potential impact of COVID-19.
5/14/21
Munir MA, Tandiabang PA, Setyawati T, et al. | Transfus Clin Biol
Aim: To analyze the bioethical issues surrounding the potential use and study of convalescent plasma therapy in COVID-19.
5/14/21
Lim KH, Soong F, Low YF, et al. | J Clin Virol
Aim: To determine the clinical manifestations of neonatal COVID-19 and outcomes based on severity groups. 
5/14/21
De Crescenzo F, Amato L, Cruciani F, et al. | Front Pharmacol
Aim: To assess the comparative efficacy and safety of pharmacological interventions for COVID-19.
RECENTLY UPDATED
5/14/21
Mourmouris P, Tzelves L, Roidi C, et al. | Osong Public Health Res Perspect
Aim: To identify the potential and definite sources of transmission of coronavirus disease 2019 (COVID-19).
5/14/21
Kwee RM, Adams HJA, Kwee TC | Radiol Cardiothorac Imaging
Aim: To determine the diagnostic performance of the COVID-19 Reporting and Data System (CO-RADS) and the Radiological Society of North America (RSNA) categorizations in patients with clinically suspected coronavirus disease 2019 (COVID-19) infection.
5/14/21
Zhan H, Chen H, Liu C, et al. | Clin Appl Thromb Hermost
Aim: To assess the predictive value of D-dimer for the severity, mortality and incidence of venous thromboembolism (VTE) events in COVID-19 patients.
5/14/21
Khodeir MM, Shabana HA, Alkhamiss AS, et al. | J Infect Public Health
Aim: To review different biomarkers to systematically analyze these values to evaluate whether are they are correlated with the severity of COVID-19 disease and so their ability to be a predictor for progression.
5/14/21
Siow I, Lee KS, Zhang JJY, et al. | Eur J Neurol
Aim: To describe the incidence, clinical course and outcomes of patients who suffer from encephalitis as a complication of COVID-19.
RECENTLY UPDATED
5/14/21
Chambergo-Michilot D, Barros-Sevillano S, Rivera-Torrejon O, et al. | Eur J Neurol
Aim: To systematically review the factors associated with COVID-19 in people with PD.
RECENTLY UPDATED
5/14/21
Heath L, Carey M, Lowney AC, et al.  | Palliat Med
Aim: To determine the dose ranges of pharmacological interventions commonly used to manage symptoms in adult patients dying of COVID-19, establish how effectiveness of these interventions was measured, and whether the pharmacological interventions were effective.
RECENTLY UPDATED
5/14/21
Paternoster G, Bertini P, Innelli P, et al. | J Cardiothorac Vasc Anesth
Aim: To describe the features of right ventricular impairment and pulmonary hypertension in coronavirus disease (COVID-19) and assess their effect on mortality.
RECENTLY UPDATED
5/14/21
James PT, Ali Z, Armitage AE, et al. | J Nutr
Aim: To review the latest evidence on how malnutrition across all its forms (under- and overnutrition and micronutrient status) may influence both susceptibility to, and progression of, COVID-19.
5/13/21
Nobari NN, Seirafianpour F, Dodangeh M, et al. | Exp Dermatol
Aim: To collect the mucocutaneous histopathologic data of COVID-19 patients for future investigations and interpretations. 
5/13/21
Kang S, Gong X, Yuan Y | Epidemiol Infect
Aim: To systematically assess the association between smoking and cardiovascular disease and disease progression among novel coronavirus pneumonia (COVID-19) cases.
RECENTLY UPDATED
5/13/21
Ahammed T, Anjum A, Rahman MM, et al. | Health Sci Rep
Aim: To estimate the R0 and CFR of COVID-19 and assess whether the parameters vary in different regions of the world.
RECENTLY UPDATED
5/13/21
Martimbianco ALC, Pacheco RL, Bagattini AM, et al. | Int J Clin Pract
Aim: To identify, systematically evaluate and summarise the best available evidence on the frequency of long COVID (post-acute COVID-19 syndrome), its clinical manifestations and the criteria used for diagnosis.
RECENTLY UPDATED
5/13/21
Okoli GN, Rabbani R, Copstein L, et al. | Infect Dis
Aim: To review the evidence on the treatment of COVID-19 with remdesivir.
5/13/21
Moezzi M, Shirbandi K, Shahvandi HK, et al. | Inform Med Unlocked
Aim: To summarize all the data currently available on the AI-assisted CT-Scan prediction accuracy for COVID-19.
5/12/21
Round T, L'Esperance V, Bayly J, et al. | Br J Cancer
Aim: To review the evidence on delivering lung cancer care during the COVID-19 pandemic.
5/12/21
Lin Z, Chen J, Han S | Expert Rev Anticancer Ther
Aim: To assess whether anti-cancer therapies such as surgery, chemotherapy, immunotherapy, and targeted therapy will increase the severity and mortality of cancer patients with COVID-19.
5/12/21
Azene AG, Workie MS, Aragaw AM | Curr Ther Res Clin Exp
Aim: To assess the pooled status of knowledge, attitude, and prevention practices regarding COVID -19 in Ethiopia.
5/11/21
Shorey SY, Ng ED, Chee CYI | Scand J Public Health
Aim: To examine the prevalence of antenatal and postnatal anxiety and depressive symptoms among pregnant women and postpartum mothers during the COVID-19 period.
5/11/21
Keshavarz P, Yazdanpanah F, Azhdari S, et al. | J Med Virol
Aim: To demonstrate the relationship between severely ill cases of MIS-C and COVID-19.
5/11/21
Galanis P, Vraka I, Fragkou D, et al. | Am J Infect Control
Aim: To assess the impact of PPE use on HCWs' physical health and we examined factors related to a greater risk of adverse events due to PPE use.
5/11/21
Rachel JB, Gururaj N, Smitha T, et al. | J Oral Maxillofac Pathol
Aim: To understand study the strain variants, all possible modes of transmission, pathogenesis, and manifestations mentioned in predominant literature published during the pandemic.
5/11/21
Born J, Beymer D, Rajan D, et al. | Patterns
Aim: To address the utility of AI in imaging for COVID-19 patient care.
5/11/21
Zippi M, Fiorino S, Budriesi R, et al. | World J Clin Cases
Aim: To identify studies on the relationship between the intake of PPIs and coronavirus disease 2019 (COVID-19) in patients affected by SARS-CoV-2 infection.
5/11/21
Las Casas Lima MH, Cavalcante ALB, Leão SC | Braz J Otorhinolaryngol
Aim: To analyze current scientific evidence intended to elucidate the pathophysiological relationship between COVID-19 and the cause of olfactory disorders.
5/11/21
Jaffe TA, Hayden E, Uscher-Pines L, et al. | J Am Coll Emerg Physicians Open
Aim: To describe the landscape of telehealth initiatives in emergency care that have been described during the coronavirus disease 2019 pandemic.
5/11/21
Oscanoa TJ, Amado J, Vidal X, et al. | Adv Respir Med
Aim: To conduct a metanalysis of the association between 25-hydroxyvitamin D (25(OH)D) concentration and SARS-CoV-2 infection severity or mortality.
5/11/21
Wijaya I, Andhika R, Huang I, et al. | Clin Epidemiol Glob Health
Aim: To assess the efficacy of JAK inhibitors in terms of clinical outcome, including mortality, clinical improvement, and clinical deterioration among hospitalized COVID-19 patients.
RECENTLY UPDATED
5/11/21
Chowdhury N, Khalid A, Turin TC | Z Gesundh Wiss
Aim: To quickly synthesize existing literature about misinformation during recent abrupt large-scale infectious disease outbreaks.
5/10/21
Kim H, Hwang H, Hong H, et al. | Sci Rep
Aim: To review the differences in risk factors for critical outcomes of patients with COVID-19 according to the continent on which the studies were performed.
5/10/21
Taha M, Samavati L | RMD Open
Aim: To examine the prevalence of aPL and its clinical impact in patients with COVID-19.
5/10/21
Ghodsi A, Bijari M, Alamdaran SA, et al. | World J Pediatr
Aim: To evaluate the chest computed tomography (CT) findings in infants with confirmed COVID-19 infection
5/10/21
Dong Y, Shamsuddin A, Campbell H, et al. | J Glob Health
Aim: To describe existing SARS-CoV-2 therapeutic approaches and present the results of their current COVID-19 clinical trials.
5/10/21
Menon T, Gandhi SAQ, Tariq W, et al. | Cureus
Aim: To provide an association between CKD and the clinical prognosis of COVID-19.
5/10/21
Saadatjoo S, Miri M, Hassanipour S, et al. | Public Health
Aim: To investigate and synthesize the current evidence on knowledge, attitudes, and practices (KAPs) of the general population regarding COVID-19.
5/10/21
Ippolito M, Catalisano G, Marino C, et al. | Resuscitation
Aim: To estimate the mortality rate, the rate of return of spontaneous circulation (ROSC) and survival with favorable neurological outcome in patients with COVID-19 after in-hospital cardiac arrest (IHCA) and attempted cardiopulmonary resuscitation (CPR).
5/10/21
Musuuza JS, Watson L, Parmasad V, et al. | PLoS One
Aim: To examine the occurrence of co-infections and superinfections and their outcomes among patients with SARS-CoV-2 infection.
5/10/21
Turner S, Botero-Tovar N, Herrera MA, et al. | Implement Sci
Aim: To depict the experiences and perceptions of organisations and actors at multiple levels of health systems internationally in responding to COVID-19.
RECENTLY UPDATED
5/10/21
Klassen SA, Senefeld JW, Johnson PW | Mayo Clin Proc
Aim: To determine the effect of COVID-19 convalescent plasma on mortality.
5/10/21
Lazaridis D, Leung S, Kohler L, et al. | J Pharm Pract
Aim: To review the evidence on the impact of anticoagulation on COVID-19 patient outcomes.
5/7/21
Watt JA, Lane NE, Veroniki AA, et al. | J Am Geriatr Soc
Aim: To compare the diagnostic accuracy of virtual to in-person cognitive assessments and tests and barriers to virtual cognitive assessment implementation.
DIAGNOSTICS
5/7/21
Gulsen A, Konig I, Jappe U, et al. | Respirology
Aim: To examine in detail whether the underlying chronic obstructive pulmonary diseases (COPD), asthma and chronic respiratory diseases (CRDs) were associated with an increased risk of more severe COVID-19. 
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
5/7/21
Mutiawati E, Syahrul S, Fahriani M, et al. | F1000Res
Aim: To determine the prevalence of headache in coronavirus disease 2019 (COVID-19) and to assess its association as a predictor for COVID-19.
CLINICAL CHARACTERISTICS
5/7/21
Aladawi M, Elfil M, Abu-Esheh B, et al. | Can J Neurol Sci
Aim: To review the evidence on the association between Guillain Barre Syndrome and COVID-19.
CLINICAL CHARACTERISTICS
5/7/21
Dembrovszky F, Váncsa S, Farkas N, et al. | Viruses
Aim: To evaluate which prognostic factors may impact repeated SARS-CoV-2 positivity (RSP) and their association with immunoglobulin detectability among recovered patients. 
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
5/7/21
Rosenberger KJ, Xu C, Lin L | J Eval Clin Pract
Aim: To methodologically assess the current systematic reviews and meta-analyses on COVID-19.
5/7/21
Aldien AS, Ganesan GS, Wahbeh F, et al. | Cardiovasc Revasc Med
Aim: To investigate the possible role of hyperinflammation in inducing cardiac injury as one of the severe complications of COVID-19.
CLINICAL CHARACTERISTICS
5/7/21
Lu Y, Zhao J, Ye M, et al. | Neurol Sci
Aim: To determine the risk of acute ischemic stroke in patients with severe and non-severe coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
5/7/21
Cosco TD, Best J, Davis D, et al. | Age Aging
Aim: To quantify the association between frailty and COVID-19 in relation to mortality in hospitalised patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
5/6/21
Chee ML, Ong MEH, Siddiqui FJ, et al. | Int J Environ Res Public Health
Aim: To systematically review and critically appraise the current evidence on AI applications for COVID-19 in intensive care and emergency settings.
DIAGNOSTICS
5/6/21
Ayubi E, Bashirian S, Khazaei S | J Gastrointest Cancer
Aim: To systematically review and meta-analysis of studies that evaluated the level of depression and anxiety in cancer patients during the COVID-19 pandemic.
MENTAL HEALTH
5/6/21
Angelico R, Blasi F, Manzia TM, et al. | Medicina
Aim: To investigate the current management of IS therapy in KT recipients with COVID-19. 
CLINICAL CHARACTERISTICS
5/6/21
Suklan J, Cheaveau J, Hill S, et al. | Viruses
Aim: To statistically summarise routine laboratory biomarker measurements in COVID-19-positive and -negative patients to inform future work.
DIAGNOSTICS
5/6/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the role of daycares and schools in the transmission of COVID-19.
RECENTLY UPDATED
5/5/21
Shah R, Priyadarshini G, Parsana M | Indian J Otolaryngol Head Neck Surg
Aim: To give a brief review of available data on COVID-19 related to the timing, personal protections, operative steps modifications, and subsequent post tracheostomy care during this pandemic.
CANDIDATE THERAPEUTICS
5/5/21
Szarpak L, Borkowska M, Peacock FW, et al. | Cardiol J
Aim: To review interventional outcome studies in patients with in-hospital cardiac arrest before and during the coronavirus disease 2019 (COVID-19) pandemic period.
CLINICAL CHARACTERISTICS
5/5/21
Li X, Zhong X, Wang Y, et al. | PLoS One
Aim: To systematically identify the possible risk factors responsible for severe cases.
CLINICAL CHARACTERISTICS
5/5/21
Yousefi M, Oskoei V, Jafari AJ, et al. | Environ Sci Pollut Res Int
Aim: To determine the effects of COVID-19 on the quantity of waste and municipal solid waste management.
INFECTION CONTROL
5/5/21
Chetty T, Ramokolo V, Rees K, et al. | S Afr Med J
Aim: To assess the effectiveness of cloth and medical masks for preventing SARS-CoV-2 transmission in community settings.
INFECTION CONTROL
5/5/21
Rehman MA, Farooq H, Ali MM, et al. | SN Compr Clin Med
Aim: To identify cases of subacute thyroiditis associated with COVID-19 and evaluated patient-level demographics, major clinical features, laboratory findings and outcomes.
CLINICAL CHARACTERISTICS
5/4/21
Du P, Li D, Wang A, et al. | Can J Infect Dis Med Microbiol
Aim: To screen the risk factors for severe illness and death and provide help for early clinical treatment of the new coronavirus (COVID-19).
CLINICAL CHARACTERISTICS
5/4/21
Bilal U, Gullón P, Padilla-Bernáldez J | Gac Sanit
Aim: To review the scientific epidemiologic evidence on the role of hospitality venues in the incidence or mortality from COVID-19.
INFECTION CONTROL
5/4/21
Dos Santos ACM, Dos Santos BRC, Dos Santos BB, et al. | Infect Genet Evol
Aim: to review the effect of single nucleotide polymorphisms in the development of severe acute respiratory syndrome (SARS).
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
5/4/21
Hariyanto TI, Rosalind J, Christian K, et al. | South Afr J HIV Med
Aim: To explore the impact of HIV and SARS-CoV-2 co-infection on mortality.
CLINICAL CHARACTERISTICS
5/4/21
Nepal G, Shrestha GS, Rehrig JH, et al. | J Nepal Health Res Counc
Aim: To review the evidence on neurological involvement in COVID-19 associated MIS-C.
CLINICAL CHARACTERISTICS
5/4/21
Liang M, Luo N, Chen M, et al. | Infect Dis Ther
Aim: To investigate the prevalence and mortality in PLWHA co-infected with COVID-19.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
5/3/21
Peixoto AO, Costa RM, Uzun R, et al. | Pulmonology
Aim: To review the evidence on the use of lung ultrasound in COVID-19.
5/3/21
Pb S, Mittal S, Madan K, et al. | Monaldi Arch Chest Dis
Aim:  To evaluate the available evidence and performed meta-analysis of the effect of awake PP in non-intubated patients on improvement in oxygenation and reducing the need for intubation.
5/3/21
Siegel A, Zuo Y, Moghaddamcharkari N, et al. | Curr Opin Psychiatry
Aim: To synthesize the extant literature reporting on barriers of telemental health (TMH) during the COVID-19 pandemic and how facilities have worked to overcome these barriers, to inform best practices for TMH delivery.
5/3/21
Neira C, Godinho R, Rincon F, et al. | Nutrients
Aim: To evaluate the current evidence about the impact that preventive measures of physical contact restriction causes in healthy nutrition.
RECENTLY UPDATED
5/3/21
Gianfredi V, Mauer NS, Gentile L, et al. | Int J Environ Res Public Health
Aim: To evaluate the available scientific evidence on the risks of recreational skiing for the evolution of the COVID-19 pandemic.
5/3/21
Corrao S, Mallaci Bocchio R, Lo Monaco M, et al. | Nutrients
Aim: To analyze the current knowledge from systematic reviews of the relationship between nutraceutical supports and the reduction in inflammatory response to formulate clinical recommendations and highlight directions for future research during the COVID-19 pandemic. 
5/3/21
Nobari H, Fashi M, Eskandari A, et al. | Int J Environ Res Public Health
Aim: To assess and provide an up-to-date analysis of the impact of coronavirus disease 2019 (COVID-19) pandemic on the health-related quality of life (HRQoL) of children and adolescents.
5/3/21
Tleyjeh IM, Kashour Z, Riaz M, et al. | Clin Microbiol Infect
Aim: To perform a living systematic review of the literature about the efficacy and toxicity of the IL-6 receptor antagonist, tocilizumab, in COVID-19 patients.
RECENTLY UPDATED
CANDIDATE THERAPEUTICS
5/3/21
Regmi K, Lwin CM | Int J Environ Res Public Health
Aim: To review the factors associated with the implementation of NPIs (social distancing, social isolation and quarantine) for reducing COVID-19.
5/3/21
La Verde M, Riemma G, Torella M, et al. | Int J Gynaecol Obstet
Aim: To evaluate the characteristics of pregnant women deceased due to COVID-19.
RECENTLY UPDATED
5/3/21
Putri C, Hariyanto TI, Hananto JE, et al. | Parkinsonism Relat Disord
Aim: To analyze the relationship between PD and in-hospital outcomes of COVID-19.
5/3/21
Diaz-Arocutipa C, Saucedo-Chinchay J, Imazio M, et al. | J Cardiovasc Med
Aim: To summarize the clinical features, diagnostic methods, treatment, and outcomes of coronavirus disease 2019 (COVID-19) patients with pericarditis.
5/3/21
Ponnapa Reddy M, Subramaniam A, et al. | Crit Care Med
Aim: To evaluate the impact of prone positioning on oxygenation and clinical outcomes.
5/3/21
Mojahed A, Brym S, Hense H, et al. | Front Psychiatry
Aim: To review the evidence on the context of social and geographical isolation and their associations with intimate partner violence.
5/3/21
Dramé M, Cofais C, Hentzien M, et al. | Nutrients
Aim: To identify and synthesize the best available evidence on the association between vitamin D level and risk of COVID-19, adverse outcomes and possible benefits of supplementation aged 60 years or over.
RECENTLY UPDATED
5/3/21
Magnavita N, Chirico F, Garbarino S, et al. | Int J Environ Res Public Health
Aim: To summarize and combine relevant data from existing systematic reviews and meta-analyses in order to evaluate the association of coronaviruses (SARS, MERS, SARS-CoV-2) with BOS in HCWs.
5/3/21
Mogensen MA, Wangaryattawanich P, Hartman J, et al. | Br J Radiol
Aim: To describe outcomes associated with abnormal neuroimaging findings among adult COVID-19 patients.
CLINICAL CHARACTERISTICS
5/3/21
Hasan T, Beardsley J, Marais BJ, et al. | Vaccines
Aim: To assess the publicly-available policies and implementation strategies used for COVID-19 mass vaccination.
5/3/21
Bareille M, Hardy M, Douxfils J, et al. | J Clin Med
Aim: To assess the potential usefulness of viscoelastometric testing (VET) to predict thrombotic events in COVID-19 patients.
4/30/21
 | NSW Health COVID-19 Critical Intelligence Unit
4/30/21
Sahu AK, Mathew R, Aggarwal P, et al. | J Glob Infect Dis
Aim: To investigate the clinical characteristics that can predict COVID-19 disease severity.
MENTAL HEALTH
4/30/21
 | NSW Health COVID-19 Critical Intelligence Unit
4/30/21
Lee J, Song J | J Med Virol
Aim: To investigate the diagnostic accuracy of the Xpert Xpress and the ID NOW assays for rapid detection of SARS-CoV-2.
CLINICAL CHARACTERISTICS
4/30/21
Blum P, Putzer D, Liebensteiner MC, et al. | In Vivo
Aim: To provide a systematic review of the published literature on the impact by the Covid-19 pandemic on orthopaedic and traumatological care by focusing on the number of clinical visits, surgeries and reasons for consultation.
4/30/21
Laali A, Tabibzadeh A, Esghaei P, et al. | Adv Biomed Res
Aim: To review the evidence on liver function tests profile in COVID-19 patients at the admission time.
INFECTION CONTROL
4/30/21
Peiris S, Mesa H, Aysola A, et al. | PLoS One
Aim: To summarize the reported pathologic findings on biopsy and autopsy in patients with severe/fatal COVID-19 and documented the presence and/or effect of SARS-CoV-2 in all organs.
CLINICAL CHARACTERISTICS
4/30/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on what is known about reasons for vaccine confidence and uptake in populations experiencing inequities.
4/30/21
Zhang L, Pan R, Cai Y, et al. | Psychiatry Investig
Aim: To investigate the prevalence of post-traumatic stress disorder (PTSD) in the general population during the COVID-19 pandemic.
DIAGNOSTICS
4/29/21
Córdova LDS, Vega APM, Luján-Carpio E, et al. | Dement Neuropsychol
Aim: To describe the characteristics of COVID-19 patients, both over and under 80 years old, by conducting a systematic review of the literature describing case reports, and to summarize and critically assess these characteristics.
4/29/21
Schlesinger S, Neuenschwander M, Lang A, et al. | Diabetologia
Aim: To identify high-risk phenotypes of diabetes associated with COVID-19 severity and death.
4/29/21
Choudary MC, Crain CR, Qiu X, et al.  | Clin Infect Dis
Aim: To characterize the hallmarks of reinfecting sequences and the rate of viral evolution in persistent infection.
UPDATED
CLINICAL CHARACTERISTICS
4/29/21
Rogers JP, Chesney E, Oliver D, et al. | Epidemiol Psychiatr Sci
Aim: To establish whether infectious epidemics are associated with any changes in the incidence of suicide or the period prevalence of self-harm, or thoughts of suicide or self-harm, with a secondary objective of establishing the frequency of these outcomes.
4/28/21
Ren X, Ren X, Lou J, et al. | EClinicalMedicine
Aim: To comprehensively analyze the COVID-19 patients with RP RT-PCR result after discharged through the inclusion of extensive relevant studies; focus on the clinical characteristics, the possible causes and risk factors.
4/28/21
Elavarasi A, Sahoo RK, Seth T, et al. | Natl Med J India
Aim: To review the evidence on anti-IL-6 therapies in the treatment of COVID-19.
4/28/21
Hayward SE, Deal A, Cheng C, et al. | J Migr Health
Aim: To assess clinical outcomes of COVID-19 in migrant populations (cases, hospitalisations, deaths), indirect health and social impacts, and to determine key risk factors.
UPDATED
CLINICAL CHARACTERISTICS
4/28/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on COVID-19 vaccination for immunocompromised patients including risks and adverse events, efficacy and advice from professional colleges.
4/28/21
Bartoszko JJ, Siemieniuk RAC, Kum E, et al. | BMJ
Aim: To determine and compare the effects of drug prophylaxis on severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (covid-19).
UPDATED
4/27/21
Sheikh AB, Chourasia PK, Javed N, et al. | J Neuroimmunol
Aim: To determine demographic characteristics, clinical features, lab evaluation, management and complications of the studies focusing on Guillain-Barre syndrome (GBS) as a sequele of novel coronavirus (COVID-19) infection.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Vassilopoulou E, Feketea G, Koumbi L, et al. | Front Immunol
Aim: To summarize the current evidence, collected in a systematic literature search and narrative review of original articles related to breastfeeding by SARS-CoV-2–infected mothers, and deploying knowledge gained from other respiratory virus-transmitted diseases about the protective anti-inflammatory effects of breastfeeding. 
INFECTION CONTROL
4/27/21
Yu J, Wu B, Feng L, et al. | J Tissue Viability
Aim: To summarize the pressure injuries caused by COVID-19 and the corresponding preventive measures and treatments.
CLINICAL CHARACTERISTICS
4/27/21
Siemieniuk RAC, Bartoszko JJ, Ge L, et al. | BMJ
Aim: To compare the effects of treatments for coronavirus disease 2019 (covid-19).
UPDATED
CANDIDATE THERAPEUTICS
4/27/21
Mitaka H, Kuno T, Takagi H, et al. | Mycoses
Aim: To determine the incidence and mortality of CAPA in critically ill patients with COVID-19 to improve guidance on surveillance and prognostication.
CLINICAL CHARACTERISTICS
4/27/21
Spielberger BD, Goerne T, Geweniger A, et al. | Front Pediatr
Aim: To systematically review the current evidence on transmission of SARS-CoV-2 to and by children.
INFECTION CONTROL
4/27/21
Bansal V, Mahapure KS, Mehra I, et al. | Front Med
Aim: To appraise the currently available data for the clinical usefulness of convalescent plasma for the treatment of COVID-19. 
CANDIDATE THERAPEUTICS
4/27/21
Patralekh MK, Jain V, Iyengar K, et al.  | J Clin Orthop Trauma
Aim: To evaluate the impact of COVID-19 on patients with PFF and assessed associated mortality.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Hossain MM, Rahman M, Trisha NF, et al. | Heliyon
Aim: To estimate the pooled prevalence of anxiety and depression in South Asia during COVID-19. 
MENTAL HEALTH
4/27/21
Ouyang L, Yu M, Zhu Y, et al. | Heliyon
Aim: To describe the respiratory supports and determine their association with clinical outcomes of COVID-19 patients in intensive care unit (ICU).
CANDIDATE THERAPEUTICS
4/27/21
Wu Y, Li H, Zhang Z, et al. | Ann Palliat Med
Aim: To evaluate the in-hospital mortality and risk factors of death in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Mackey K, Kansagara D, Vela K | Ann Intern Med
Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.
UPDATED
WHO COLLABORATIVE
VA ESP
4/26/21
Garcia-Zamora S, Lee S, Haseeb S, et al. | Pacing Clin Electrophysiol
Aim: To examine the prevalence of cardiac arrhythmias detected by the electrocardiogram and their relationships with adverse outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Barreira DF, Lourenço RA, Calisto R, et al. | Front Med
Aim: To evaluate the potential of using CP or enriched antibodies from plasma (hyperimmune plasma) for the treatment of COVID-19 in comparison to standard treatment (ST) (treatments performed without CP), in clinical trials.
CANDIDATE THERAPEUTICS
4/26/21
Singh RK, Bajpai R, Kaswan P | Clin Epidemiol Glob Health
Aim: To systematically review existing literature reporting the prevalence of psychological wellbeing (such as stress, anxiety, depression, psychological distress & sleep disorders, etc.), particularly from the Indian perspective as a limited evidence synthesis published so far.
MENTAL HEALTH
4/26/21
Varghese A, George G, Kondaguli SV, et al. | J Glob Health
Aim: To explore the prevalence and determinants of mental health outcomes (anxiety, stress, depression, PTSD, insomnia) among nurses across the globe due to the COVID-19.
UPDATED
MENTAL HEALTH
4/26/21
Ma Z, Wang MP, Liu L, et al. | Aging
Aim: To review the evidence on whether ACEI and/or ARB are associated with the risk of SARS-COV2 infection and whether they are associated with adverse outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Muller AE, Himmels JPW, Van de Velde S | BMC Med Res Methodol
Aim: To review the diagnostic tests developed to assess or diagnose COVID-19-related fear or phobia.
UPDATED
MENTAL HEALTH
4/26/21
Wolf S, Seiffer B, Zeibig JM, et al. | Sports Med
Aim: To provide a systematic overview of the literature with regard to associations between physical activity (PA) and depression and anxiety during the COVID-19 pandemic.
MENTAL HEALTH
4/26/21
Singh J, Malik P, Patel N, et al. | Clin Exp Med
Aim: To identify prevalence and association of comorbid chronic kidney disease (CKD), acute kidney injury (AKI) and utilization prevalence of continuous renal replacement therapy (CRRT) in COVID-19-hospitalized patients as a function of severity status. 
CLINICAL CHARACTERISTICS
4/26/21
Parsons N, Outsikas A, Parish A, et al. | AJNR Am J Neuroradiol
Aim: To quantitatively evaluate whether a network diffusion model can explain the spread of small neurologic events.
CLINICAL CHARACTERISTICS
4/26/21
Hariyanto TI, Kurniawan A | Sleep Med
Aim: To analyze the relationship between OSA and poor outcomes of COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Dmytriw AA, Chibbar R, Chen PPY, et al. | Expert Rev Respir Med
Aim: To review the evidence on the outcomes of patients with COVID-19-related ARDS compared to ARDS unrelated to COVID-19.
CLINICAL CHARACTERISTICS
4/26/21
Gascon L, Fournier I, Chiesa-Estomba C, et al. | Eur Arch Otorhinolaryngol
Aim: To summarize, in a systematic way, all available guidelines and provide clear guidelines for the management of head and neck cancer patients in the COVID-19 pandemic.
INFECTION CONTROL
4/26/21
Bakaloudi DR, Jeyakumar DT, Jayawardena R, et al. | Clin Nutr
Aim: To investigate changes in specific dietary habits (snacking, fast-foods, ordered food) and alcohol consumption during the COVID-19 lockdown period compared to pre lockdown time.
MENTAL HEALTH
4/26/21
Souza LFF, Paineiras-Domingos LL, Melo-Oliveira MES, et al. | Cien Saude Colet
Aim: To evaluate the sleep quality in individuals during the COVID-19 pandemic by Pittsburgh Sleep Quality Index (PSQI).
MENTAL HEALTH
4/26/21
Chong WH, Neu KP | J Hosp Infect
Aim: To discuss the incidence, characteristics, diagnostic criteria, biomarkers, and outcomes of hospitalized patients diagnosed with CAPA.
CLINICAL CHARACTERISTICS
4/26/21
Iwu CJ, Iwu CD, Wiysonge CS | Pan Afr Med J
Aim: To synthesize evidence on the long-term effects of the SARS-CoV-2 infection among survivors.
CLINICAL CHARACTERISTICS
4/22/21
Thakur B, Dubey P, Benitez J, et al.  | Sci Rep
Aim: To determine geographical, age, and gender related differences in the prevalence of comorbidities and associated severity and mortality rates among COVID-19 patients.
CLINICAL CHARACTERISTICS
4/22/21
Lu W, Zheng Y, Liu J, et al.  | Aging
Aim: To evaluate the efficacy and safety of lopinavir/ritonavir antiviral treatment in patients with SARS, MERS, and COVID-19.
CANDIDATE THERAPEUTICS
4/22/21
Chan KIP, Salonga AEM, Khu KJO | Surg Neurol Int
Aim: To review the evidence on decompressive hemicraniectomy for acute ischemic stroke and share a case presentation.
CANDIDATE THERAPEUTICS
4/22/21
Menon T, Sharma R, Saurabh K, et al.  | Cureus
Aim: To measure the prevalence of acute kidney injury (AKI) in COVID-19 and its association with the disease severity and mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/22/21
Qiu R, Li J, Xiao Y, et al.  | Medicine
Aim: To evaluate the efficiency and safety of the COVID-19 medicine.
CANDIDATE THERAPEUTICS
4/21/21
Moonla C, Sosothikul D, Chiasakul T, et al. | Clin Appl Thromb Hermost
Aim: To estimate pooled odds ratios (ORs) of in-hospital mortality and major bleeding comparing among intermediate-to-therapeutic dose AC, prophylactic dose AC, and no AC.
CANDIDATE THERAPEUTICS
4/21/21
Chaudhuri D, Sasaki K, Aram K, et al. | Intensive Care Med
Aim: To summarize all RCTs examining the use of corticosteroids in ARDS.
CANDIDATE THERAPEUTICS
4/21/21
Chowdhury AI, Alam MR, Rabbi MF, et al.  | Obes Med
Aim: To estimate the effects of overweight and obesity on COVID-19 disease severity.
CLINICAL CHARACTERISTICS
4/21/21
Medaglia AA, Siracusa L, Gioè C, et al.  | Ital J Pediatr
Aim: To review the medical literature on Kawasaki disease recurrence and reported a new case of Kawasaki disease recurrence in a child with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
4/21/21
Dy LF, Lintao RCV, Cordero CP, et al.  | Sci Rep
Aim: To estimate the proportion of COVID-19 patients with cardiac abnormalities and to determine the association between the cardiac abnormalities in COVID-19 patients and disease severity and mortality.
CLINICAL CHARACTERISTICS
4/20/21
Cheng MP, Cau A, Lee TC, et al.  | Crit Care Med
Aim: To compare the rates of cardiac injury by angiotensin-converting enzyme-2-binding viruses from viruses that do not bind to angiotensin-converting enzyme-2.
CLINICAL CHARACTERISTICS
4/20/21
Pizarro-Pennarolli C, Sánchez-Rojas C, Torres-Castro R, et al.  | PeerJ
Aim: To understand the impact of COVID-19 on ADL performance of adult patients and to describe the common scales used to assess performance of ADL on patients post-COVID-19.
CLINICAL CHARACTERISTICS
4/20/21
Sathian B, Asim M, Banerjee I, et al.  | Nepal J Epidemiol
Aim: To evaluate the safety and immunogenicity of novel COVID-19 vaccine candidates under clinical trial evaluation and present a contemporary update on the development and implementation of a potential vaccines.
INFECTION CONTROL
4/20/21
Artemios A, Andreas L, Hadjigeorgiou L, et al. | Neurol Res
Aim: To characterize all – to date – reported cases with COVID-19 related myelopathy.
CLINICAL CHARACTERISTICS
4/20/21
Mondello C, Roccuzzo S, Malfa O, et al.  | Front Pharmacol
Aim: To review the main post-mortem findings reporting data on the infection effects on several organs.
CLINICAL CHARACTERISTICS
4/20/21
Parra-Medina R, Herrera S, Jaime M, et al. | Acta Haematol
Aim: To review cases in the literature about COVID-19 autopsies that reported microthrombi in different organs.
CLINICAL CHARACTERISTICS
4/19/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy of rapid, point-of-care tests for COVID-19.
4/17/21
Sing A, Hussain S, Antony B | Diabetes Metab Syndr
Aim: To systematically review the evidence on clinical outcomes in NAFLD patients with COVID-19.
CLINICAL CHARACTERISTICS
4/17/21
Barcelos IDES, Penna IAA, Soligo AG, et al. | Rev Bras Ginecol Obstet
Aim: To evaluatee the available evidence on vertical transmission by severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2.
INFECTION CONTROL
4/16/21
Akbar MR, Wibowo A, Pranata R, et al. | Front Nutr
Aim: To assess whether low serum 25-hydroxyvitamin D (25-OHD) level is associated with susceptibility to COVID-19, severity, and mortality related to COVID-19.
CLINICAL CHARACTERISTICS
4/16/21
Damiano RF, Di Santi D, Beach S, et al. | Braz J Psychiatry
Aim: To review the most common mental health strategies aimed at alleviating and/or preventing mental health problems in individuals during the coronavirus disease 2019 (COVID-19) and other coronavirus pandemics.
UPDATED
MENTAL HEALTH
4/16/21
Zuin M, Rigatelli G, Bilato C, et al. | J Interv Card Electrophysiol
Aim: To investigate the pooled prevalence of pre-existing AF and its short-term mortality risk in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/15/21
Kashetsky N, Mukovozov IM, Bergman J. | J Cutan Med Surg
Aim: To summarize reports of CLL coinciding with SARS-CoV-2 infection to clarify the prevalence, clinical relevance, and prognostic value of these lesions.
CLINICAL CHARACTERISTICS
4/15/21
De Armond M, Feliciano S, Hirabayashi E, et al.  | JBI Evid Synth
4/15/21
Parisi R, Costanzo S, Di Castelnuovo A, et al. | Semin Thromb Hemost
Aim: To assess the association of anticoagulants and their dosage with in-hospital all-cause mortality in COVID-19 patients.
CANDIDATE THERAPEUTICS
4/15/21
Chew NW, Ow ZGW, Teo VXY, et al. | Can J Cardiol
Aim: To examine the global impact of COVID-19 pandemic on incidence of STEMI admissions, and relationship between the pandemic and door-to-balloon time (D2B), all-cause mortality and other secondary STEMI outcomes.
4/14/21
Sohrabizadeh S, Yousefian S, Bahramzadeh A, et al. | BMC Public Health
Aim: To identify the literature focused on health system response to coincidence of COVID-19 and disasters as well as describing their finding, implications and lessons-learned.
4/14/21
Qi K, Zeng W, Ye M, et al. | Medicine
Aim: To describe the clinical, laboratory, and imaging characteristics of children with COVID-19 based on published data of pediatric COVID-19 cases.
CLINICAL CHARACTERISTICS
4/14/21
Mondal R, Deb S, Shome G, et al. | Mult Scler Relat Disord
Aim: To summarize so far available pieces of evidence documenting de novo novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) mediated spinal cord demyelinating diseases.
UPDATED
CLINICAL CHARACTERISTICS
4/14/21
Flook M, Jackson C, Vasileiou E, et al. | BMC Infect Dis
Aim: To review the evidence on the risk factors for severity, disease, and mortality for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Katoto PDMC, Brand AS, Bakan B, et al. | Environ Health
Aim: To review the evidence on whether exposure to acute and chronic air pollution influences the COVID-19 epidemiologic curve.
CLINICAL CHARACTERISTICS
4/13/21
Batista P, Duque V, Luzio-Vaz A | J Infect Dev Ctries
Aim: To identify studies that describe COVID-19 related anxiety, and to understand the impact of anxiety assessment in defining strategies to be implemented in future studies.
MENTAL HEALTH
4/13/21
Yao MQ, Zheng QX, Xu J, et al. | Zhejiang Univ Sci B
Aim: To summarize the demographical, clinical, and laboratorial characteristics of non-recurrence and recurrence groups.
CLINICAL CHARACTERISTICS
4/13/21
Handayani DR, Juliastuti H, Nawangsih EN, et al. | Obes Med
Aim: To assess the prognostic value of fasting hyperglycemia in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Pranata R, Huang I, Lawrensia S, et al. | Pharmacol Rep
Aim: To address the current interest of whether the administration of PPI could increase the susceptibility and risk of poor outcome in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Labrague LJ | J Nurs Manag
Aim: To appraise and synthesize studies examining resilience, coping behaviours, and social support among healthcare workers during the coronavirus pandemic.
MENTAL HEALTH
4/13/21
 | NSW Health COVID-19 Critical Intelligence Unit
4/13/21
Hariyanto TI, Kurniawan A | Nutr Metab Cardiovasc Dis
Aim: To analyze the association between statin use and composite poor outcomes of COVID-19.
CLINICAL CHARACTERISTICS
4/13/21
Alkhatip AAAMM, Kamel MG, Hamza MK, et al. | Expert Rev Mol Diagn
Aim: To evaluate the diagnostic and prognostic accuracy of the NLR in COVID-19 patients.
DIAGNOSTICS
4/13/21
Ibekwe T, Ibekwe P, Orimadegun EA | Ann Med Surg
Aim: To review the evidence on the effectiveness of Remdesivir in the management of COVID-19.
CANDIDATE THERAPEUTICS
4/13/21
Trimboli P, Camponovo C, Scappaticcio L, et al. | Rev Endocr Metab Disord
Aim: To review the evidence on thyroid dysfunction in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/12/21
Phiri P, Ramakrishnan R, Rathod S, et al. | EClinicalMedicine
Aim: To review the evidence on the mental health impacts of the COVID-19 pandemic on healthcare professionals, patients, and the general public.
UPDATED
MENTAL HEALTH
4/12/21
Meza N, Perez-Bracchiglione J, Perez I, et al. | Medwave
Aim: To provide a timely, rigorous, and continuously updated summary of the evidence available on the role of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) in the treatment of patients with COVID-19.
UPDATED
4/12/21
Barboza JJ, Chambergo-Michilot D, Velasquez-Sotomayor M, et al. | Travel Med Infect Dis
Aim: To describe the assessment and treatment of asymptomatic infection in patients with a confirmed diagnosis of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/12/21
Badkhsh M, Dastras M, Sarchahi Z, et al. | Rev Environ Health
Aim: To evaluate the effect of CAM interventions on COVID-19 patients.
CANDIDATE THERAPEUTICS
4/12/21
Tomfohr-Madsen L, Racine N, Giesbrecht GF, et al.  | Psychiatry Res
Aim: To analyze the worldwide prevalence of depression and anxiety among pregnant women during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
4/12/21
Park M, Pawliuk C, Nguyen T, et al. | Euro Surveill
Aim: To gain an understanding of the current literature and compare the reported periods of positive SARS-CoV-2 detection from studies that conducted RT-PCR testing in addition to experiments isolating whole virus.
INFECTION CONTROL
4/12/21
Tsang NNY, So HC, Ng KY, et al. | Lancet Infect Dis
Aim: To systematically compare the diagnostic performance of different clinical specimen collection methods.
DIAGNOSTICS
4/12/21
Rakhmat II, Kusmala YY, Handayani DR, et al. | Diabetes Metab Syndr
Aim: To synthesize evidence on dipeptidyl peptidase-4 (DPP-4) inhibitor and mortality in COVID-19 patients and factors affecting it.
UPDATED
CANDIDATE THERAPEUTICS
4/12/21
Greyson SR, Auerbach AD, Mitchell MD, et al. | J Gen Intern Med
Aim: To review published guidance and collected discharge protocols and procedures to identify and synthesize common practices.
CLINICAL CHARACTERISTICS
4/12/21
Vafea MT, Zhang R, Kalligeros M, et al. | Expert Rev Med Devices
Aim: To evaluate existing information about mortality rates and effectiveness of antiviral, immune-modulating, and anticoagulation treatments in COVID-19 patients who received mechanical ventilation.
CANDIDATE THERAPEUTICS
4/12/21
Damayanthi HDWT, Prabani KIP | Arch Gerontol Geriatr
Aim: To identify the prevalence of malnutrition and levels of nutrients associated with outcomes of the older patients with COVID-19.
CLINICAL CHARACTERISTICS
4/12/21
Nguyen T, Buxton JA | Int J Drug Policy
Aim: To review the evidence on the unintended pathways between COVID-19 public health responses and increasing illicit drug overdoses.
4/12/21
Zhang Y, Cen M, Hu M, et al. | Clin Transl Gastroenterol
Aim: To evaluate the prevalence and the duration of shedding of fecal RNA in patients with COVID-19 infection.
CLINICAL CHARACTERISTICS
4/12/21
Palaiodimou L, Stefanou MI, Katsanos AH, et al. | Eur J Neurol
Aim: To critically appraise the published literature related to GBSs and COVID-19, and evaluate prevalence, clinical features and outcomes of GBSs in pateints with COVID-19 compared to non-COVID-19 contemporary or historical controls.
UPDATED
CLINICAL CHARACTERISTICS
4/12/21
Dhouib W, Maatoug J, Ayouni I, et al. | Syst Rev
Aim: To identify studies that recruited symptomatic patients, regardless of sex or age diagnosed with COVID-19, and calculated or estimated the incubation period between December 2019 and December 2020.
UPDATED
CLINICAL CHARACTERISTICS
4/9/21
Morales-Cane I, del Rocio Valverde-Leon M, Gonzalez-Gancedo J, et al. | Eur Rev Med Pharmacol Sci
Aim: To synthesize and analyze the scientific publications related to ventilatory therapies used in patients with COVID-19 in Intensive Care Units (ICUs), the parameters of invasive mechanical ventilation prescribed for these patients, and the clinical characteristics of patients admitted to the ICU.
UPDATED
CANDIDATE THERAPEUTICS
4/8/21
Mutiawati E, Fahriani M, Mamada SS, et al. | F1000Res
Aim: To determine the global prevalence of anosmia and dysgeusia in coronavirus disease 2019 (COVID-19) patients and to assess their association with severity and mortality of COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Peng HT, Rhind SG, Beckett A, et al. | JMIR Public Health Surveill
Aim: To characterize the latest advances and evidence in the use of CP for COVID-19 through a systematic review and quantitative analysis, identify knowledge gaps in this setting, and offer recommendations and directives for future research.
CANDIDATE THERAPEUTICS
4/8/21
Saragih ID, Saragih IS, Batubara SO, et al. | Geriatr Nurs
Aim: To systematically examine the association between dementia and mortality among older adults with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Rezaei S, Fatemi B, Majd ZK, et al. | Expert Rev Clin Immunol
Aim: To combine the results of clinical studies of different designs to investigate the efficacy and safety of tocilizumab in severely-to-critically ill COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
4/8/21
Islam MA, Kundu S, Alam SS, et al. | PLoS One
Aim: To conduct a systematic review and meta-analysis to estimate the overall pooled prevalence of fever and chills in addition to fever characteristics (low, medium, and high temperature) in both adult and paediatric COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Medina C, Chavira J, Aburto T, et al. | Salud Publica de Mexico
Aim: To describe the available evidence on the transmission of Covid-19 or similar acute respiratory infections in open, public spaces.
4/7/21
Sigahi TFAC, Kawasaki BC, Bolis I, et al. | Hum Factors Ergon Manuf
Aim: To investigate the impact of Covid?19 on work and workers of all occupations, reveal research gaps, and help managers to adapt to organizations amid the pandemic.
INFECTION CONTROL
4/7/21
Johnson H, Garg M, Shantikumar S, et al. | Turk J Urol
Aim: To evaluate the presence of virus in non-airborne body fluids as transmission vehicles.
INFECTION CONTROL
4/7/21
Saha S, Al-Rifai RH, Saha S | J Diabetes Metab Disord
Aim: To quantify the overall and subgroup weighted prevalence of mortality among diabetic (primary outcome) and non-diabetic (secondary outcome) and the weighted prevalence of DM (secondary outcome), in hospitalized COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/7/21
Zuin M, Rigatelli G, Bilato C, et al. | QJM
Aim: To perform a systematic review and meta-analysis of prevalence and mortality risk in COVID-19 patients with pre-existing dyslipidaemia.
CLINICAL CHARACTERISTICS
4/7/21
Camara AB, Brandao IA | Curr Med Chem
Aim: To study the receptor's family and functions most related to COVID-19 infection, also suggesting the tissue and cell location that the majority of COVID-19 receptors are mainly expressed.
CLINICAL CHARACTERISTICS
4/6/21
Kaur RJ, Dutta S, Bhardwaj P, et al. | Indian J Clin Biochem
Aim: To systematically review and synthesize the evidence on the safety data from the published COVID-19 vaccine trials.
INFECTION CONTROL
4/6/21
Sharma S, John R, Patel S, et al. | J Clin Orthop Trauma
Aim: To analyse the available evidence on bioaerosols in OSPs, and their significance in COVID-19 transmission.
INFECTION CONTROL
4/6/21
Alzahrani SH, Al-Rabia MW | Cardiol Res Pract
Aim: To assess the role of cardiac injury biomarkers measured on admission and during hospitalization as risk factors for subsequent death in COVID-19 patients.
CLINICAL CHARACTERISTICS
4/6/21
Mardi P, Esmaeili M, Iravani P, et al. | Front Pediatr
Aim: To assess the demographic, laboratory, and clinical characteristics of children with KD-like syndrome during the COVID-19 pandemic and evaluate efficacy of treatments and patients' outcome. 
CLINICAL CHARACTERISTICS
4/6/21
Hoang T | Ann Glob Health
Aim: To examine the characteristics of repositive COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
4/6/21
Yan D, Zhang X, Chen C, et al. | Front Public Health
Aim: To comprehensively summarize the VST of SARS-CoV-2.
INFECTION CONTROL
4/6/21
Hariyanto TI, Kurniawan A | J Diabetes Metab Disord
Aim: To analyze the potential association between DPP-4 inhibitor and the composite poor outcome of COVID-19.
CLINICAL CHARACTERISTICS
4/6/21
Barzkar F, Ranjbar M, Sioofy-Khojine AB, et al. | Med J Islam Repub Iran
Aim: To synthesize current evidence systematically for in vitro, animal, and human studies on the efficacy and safety of chloroquine in patients with COVID-19.
CANDIDATE THERAPEUTICS
4/6/21
Eze P, Mezue KN, Nduka CU, et al. | Am J Cardiovasc Dis
Aim: To evaluate the efficacy and safety of CQ and HCQ in the treatment of COVID-19.
CANDIDATE THERAPEUTICS
4/6/21
Yan H, Ding Y, Guo W | Psychosom Med
Aim: To quantify the prevalence of the adverse mental health outcomes in medical staff working in the hospital settings during the COVID-19 pandemic and explore the relative distribution of anxiety and depressive symptoms.
UPDATED
MENTAL HEALTH
4/6/21
Zangiabadian M, Nejadghaderi SA, Zahmatkesh MM, et al. | Front Endocrinol
Aim: To summarize the available evidence on the potential mechanism of action and the efficacy of metformin in COVID-19 patients with DM.
CANDIDATE THERAPEUTICS
4/6/21
Kollias A, Kyrikoulis KG, Lagou S, et al. | Vasc Med
Aim: To review the current evidence regarding the prevalence of VTE in patients with COVID-19 screened/assessed with lower limb ultrasonography or computed tomography pulmonary angiography.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Mirbeyk M, Saghazadeh A, Rezaei N | Arch Gynecol Obstet
Aim: To review the evidence concerning pregnant women with confirmed COVID-19 and their neonates.
CLINICAL CHARACTERISTICS
4/5/21
Monroy-Fraustro D, Maldonado-Castellanos I, Aboites-Molina M, et al. | Front Public Health
Aim: To review articles on the effectiveness of bibliotherapy on different mental health problems.
MENTAL HEALTH
4/5/21
Kopanska M, Banas-Zabczyk A, Lagowska A, et al. | J Clin Med
Aim: To review the latest research on changes in EEG in patients with COVID-19 as a basis for further quantitative electroencephalogram (QEEG) diagnostics and EEG neurofeedback training. 
CLINICAL CHARACTERISTICS
4/5/21
Byambasuren O, Dobler CC, Bell K, et al. | PLoS One
Aim: To identify valid seroprevalence studies of SARS-CoV-2 infection and compare their estimates with the reported, and imputed, COVID-19 case rates within the same population at the same time point.
INFECTION CONTROL
4/5/21
Lee KW, Yap SF, Ngeow YF, et al.  | Int J Environ Res Public Health
Aim: To determine the epidemiological characteristics, clinical signs and symptoms, blood parameters, and clinical outcomes among PLHIV who contracted COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Chmielewska B, Barratt I, Townsend R, et al. | Lancet Glob Health
Aim: To assess the collective evidence on the effects on maternal, fetal, and neonatal outcomes of the pandemic.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Borkowska MJ, Jaguszewski MJ, Koda M, et al. | J Clin Med
Aim: To review the evidence on OHCA and whether bystander reluctance to perfrom CPR deteriorates OHCA outcomes in COVID-19 patients.
INFECTION CONTROL
4/5/21
Meherali S, Punjani N, Louie-Poon S, et al. | Int J Environ Res Public Health
Aim: To identify the impact of the pandemic on children's and adolescent's mental health and to evaluate the effectiveness of different interventions employed during previous and the current pandemic to promote children's and adolescents' mental health. 
UPDATED
MENTAL HEALTH
4/5/21
Kwok CS, Dashti M, Tafuro J, et al. | Ther Adv Infect Dis
Aim: To review the evidence on cleaning, disinfection or decontamination methods in the prevention of SARS-CoV-2.
INFECTION CONTROL
4/5/21
Li YC, Lai T, Lin S, et al. | Ther Adv Chronic Dis
Aim: To evaluate the influence of pre-existing CKD on risks of all-cause mortality, hospitalization, and critically ill condition among patients with COVID-19 infection.
UPDATED
4/5/21
Necho M, Tsehay M, Birkie M, et al. | Int J Soc Psychiatry
Aim: To summarize the existing data regarding anxiety, depression, and psychological distress during the covid-19 pandemic among the wider population so that effective intervention strategies will be initiated.
MENTAL HEALTH
4/5/21
Váncsa S, Dembrovsky F, Farkas N, et al.  | Viruses
Aim: To evaluate the clinical significance of repeatedly positive testing after coronavirus disease 2019 (COVID-19) recovery.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Lin W, Hung S, Lai C, et al. | Int Immunopharmacol
Aim: To investigate the clinical efficacy and safety of tocilizumab for treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/5/21
Wildwing T, Holt N | Ther Adv Chronic Dis
Aim: To summarize findings from a systematic overview of systematic reviews of the neurological symptoms seen in patients with COVID-19. 
CLINICAL CHARACTERISTICS
4/5/21
Zhao Y, Jin Y, Rao W, et al. | J Affect Disord
Aim: To compare the prevalence of psychiatric comorbidities in all subpopulations during the SARS and COVID-19 epidemics.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Marchi R, Sugita B, Centa A, et al. | Infect Genet Evol
Aim: To describe the role, function, and association of miRNAs in SARS-CoV-2 human infection and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Wang Z, Wang Y, Yang Z, et al. | Int J Infect Dis
Aim: To appraise the quality and availability of guidelines stated and whether non-invasive ventilation in the early stage of the pandemic is of importance.
UPDATED
CANDIDATE THERAPEUTICS
4/5/21
Gisondi P, Di Leo S, Bellinato F, et al. | Dermatol Ther
Aim: To systematically review the studies reporting the time of onset of selected skin lesions with respect to the reported onset of the COVID-19 core symptoms.
UPDATED
CLINICAL CHARACTERISTICS
4/2/21
Zhao Y, Zhao L, Yang X, et al. | Rev Cardiovasc Med
Aim: To find the association between COVID-19 and cardiovascular complications. 
CLINICAL CHARACTERISTICS
4/2/21
Jacob S, Hammed A, Lam V, et al. | ANZ J Surg
Aim: To assess the consistency of national and international surgical society recommendations regarding the choice of surgical approach; assess the quality of evidence of viral emission in surgical aerosol; and assess the quality of evidence comparing aerosol generation by different surgical energy devices.
UPDATED
INFECTION CONTROL
4/2/21
Ayers CK, Kondo KK, Williams BE, et al. | J Gen Intern Med
Aim: To understand disparities in H1N1 vaccine uptake by race/ethnicity, socioeconomic status (SES), rural/urban residence, population density, and disability status, and factors associated with unequal uptake, as well as the benefits and harms of interventions designed to attenuate inequities in H1N1 vaccine uptake
UPDATED
VA ESP
INFECTION CONTROL
4/2/21
Zhao M, Zhao C, Tu S, et al. | J Integr Med
Aim: To assess the methodological quality and variability in implementation of randomized controlled trials (RCTs) for treating COVID-19, and to analyze the support that should be provided to improve data collected during an urgent pandemic situation.
4/2/21
Abdelrahman Z, Liu Q, Jiang S, et al. | Front Pharmacol
Aim: To estimate the impact of current treatments on the efficacy and safety of COVID-19 by a meta-analysis.
UPDATED
CANDIDATE THERAPEUTICS
4/2/21
Dixit S, Nandakumar G | Rev Cardiovasc Med
Aim: To explore the possible role of technological advances and social media platforms as an alternate tool in promoting a healthy living style during the COVID-19 era.
MENTAL HEALTH
4/2/21
Upshaw TL, Brown C, Smith R, et al. | PLoS One
Aim: To review the early reports on the social determinants of COVID-19 infection, health service use and health outcomes.
UPDATED
INFECTION CONTROL
4/2/21
Groom LL, McCarthy MM, Stimpfel AW, et al. | J Am Med Dir Assoc
Aim: To further explore the modalities' ability to maximize access to specialty care, modernize care models, and improve patient outcomes.
INFECTION CONTROL
4/1/21
Zhang X, Lewis AM, Moley JR | Sci Rep
Aim: To investigate the relationship between adverse COVID-19 outcomes and obesity.
CLINICAL CHARACTERISTICS
4/1/21
Baral R, Tsampasian V, Debski M, et al. | JAMA Netw Open
Aim: To conduct an updated and comprehensive systematic review and meta-analysis comparing mortality and severe adverse events (AEs) associated with receipt vs nonreceipt of ACEIs or ARBs among patients with COVID-19.
CLINICAL CHARACTERISTICS
4/1/21
Hilal N, Shaya R, Hamadeh R, et al. | Knowledge to Policy (K2P) Center
Aim: To review the evidence on the integration of COVID-19 vaccination into the services delivered by the National Primary Health Care network in Lebanon.
4/1/21
Shi Y, Guo M, Yang W, et al. | Expert Rev Vaccines
Aim: To investigate the impact of SARS-CoV-2 on neurodegenerative diseases and the latest developments in COVID-19 vaccines.
CLINICAL CHARACTERISTICS
4/1/21
Yassin A, Nawaiseh M, Shaban A, et al.  | BMC Neurol
Aim: To address the neurological aspects of COVID-19 including NM, NC, and ND findings.
UPDATED
CLINICAL CHARACTERISTICS
4/1/21
Carvalho APA, Conte-Junior CA | Glob Chall
Aim: To critically analyze nanomaterials? role as both a primary strategy (when the nanomaterials interact directly with the virus) and a secondary approach (when the nanomaterials improve the efficacy of another antiviral agent) against coronaviruses.
CANDIDATE THERAPEUTICS
4/1/21
Fathi M, Vakili K, Sayehmiri F, et al. | Iran J Immunol
Aim: To analyze the effectiveness of the measurement of specific antibodies to SARS-CoV2 (IgM and IgG) for the diagnosis of COVID-19 and to analyze the rate of SARS-CoV2 seroprevalence in the population.
DIAGNOSTICS
3/31/21
 | Health Information and Quality Authority
Aim: To explore potential populations for consideration in vaccine allocation group nine based on national and international evidence for the risk of infection, and risk of severe disease, with COVID-19.
3/31/21
Kunzler AM, Rothke N, Gunthner L, et al. | Global Health
Aim: To assess its impact on mental health during the early phase by comparing pandemic with prepandemic data and to identify potential risk and protective factors.
UPDATED
MENTAL HEALTH
3/31/21
Choudhuri AH, Duggal S, Ahuja B, et al. | Indian J Med Microbiol
Aim: To address the efficacy and safety of HCQ in SARS CoV2 by overcoming the limitations of earlier meta-analysis.
CANDIDATE THERAPEUTICS
3/30/21
Marvaldi M, Mallet J, Dubertret C, et al. | Neurosci Biobehav Rev
Aim: To estimate the prevalence of anxiety, depression, trauma-related, and sleep disorders of healthcare workers during the COVID-19 pandemic.
MENTAL HEALTH
3/30/21
Khiabani K, Amirzade-Iranaq MH | Am J Infect Control
Aim: To conduct a systemic review and meta-analysis on the reliability and sensitivity of SARS-CoV-2 detection in saliva and deep throat sputum (DTS) compared to nasopharyngeal, combined naso/oropharyngeal, and oropharyngeal swabs.
DIAGNOSTICS
3/30/21
Tang K, Hsu B, Chen D | Front Immunol
Aim: To review the evidence on the autoimmune and rheumatic manifestations associated with COVID-19.
CLINICAL CHARACTERISTICS
3/30/21
Aski BH, Anari AM, Choobdar FA, et al. | Int J Cardiol Heart Vasc
Aim: To systematically assess the incidence of such cardiac abnormalities due to MIS-C in children suffering Covid-19.
CLINICAL CHARACTERISTICS
3/30/21
Papadopoulos V, Koutroulos MV, Zikoudi DG, et al. | Diabetol Int
Aim: To examine diabetes-related acute metabolic emergencies in COVID-19 patients
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Chou R, Dana T, Buckley D, et al. | Ann Intern Med
Aim: To examine the burden of SARS-CoV-2, SARS-CoV-1, and Middle Eastern respiratory syndrome (MERS)-CoV on HCWs and risk factors for infection, using rapid and living review methods.
UPDATED
WHO COLLABORATIVE
3/30/21
Chatterji G, Patel Y, Jain V, et al. | Indian J Orthop
Aim: To synthesize this published literature to give the orthopaedic fraternity an overview about the best practices that need to be followed during this period.
INFECTION CONTROL
3/30/21
Kaminska H, Szarpak L, Kosior D, et al. | Acta Diabetol
Aim: To summarize and synthesize the evidence published about the impact of diabetes mellitus on in-hospital mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/30/21
Peter HJ, Vancsa S, Ocskay K, et al. | Front Med
Aim: To evaluate if MAFLD or NAFLD are associated with a more severe disease course of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Vidale S | Cerebrovasc Dis
Aim: To describe the clinical features and etiological characteristics of ischemic stroke patients with CO-VID-19 infection.
CLINICAL CHARACTERISTICS
3/30/21
Iheanacho CO, Odili VU, Eze UIH | Futur J Pharm Sci
Aim: To systematically review available evidence for associations between exposure to RAAS inhibitors with susceptibility to SARS-CoV-2 infection and clinical outcomes in infected persons.
CLINICAL CHARACTERISTICS
3/30/21
Sucha D, van Hamersvelt RW, van den Hoven AF, et al. | Radiol Cardiothorac Imaging
Aim: To synthesize the literature on diagnostic test accuracy of chest radiography, CT, and US for the diagnosis of coronavirus disease 2019 (COVID-19) in patients suspected of having COVID-19 in a hospital setting and evaluate the extent of suboptimal reporting and risk of bias.
UPDATED
DIAGNOSTICS
3/30/21
Mahat RK, Panda S, Rathore V, et al. | Clin Epidemiol Glob Health
Aim: To evaluate the association of inflammatory parameters with the severity and mortality in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Monica AD, Ferrara P, Dal Mas F, et al. | Ann Ig
Aim: To analyze the literature on the impact of the Covid-19 crisis on the psychological well-being of health professionals.
MENTAL HEALTH
3/30/21
Bassatne A, Basbous M, Chakhtoura M, et al.  | Metabolism
Aim: To assess the impact of vitamin D status and supplementation on COVID-19 related mortality and health outcomes.
UPDATED
CANDIDATE THERAPEUTICS
3/30/21
Petrelli F, Luciani A, Perego G, et al. | J Steroid Biochem Mol Biol
Aim: To assess the association between vitamin D and risk, severity, and mortality for COVID-19 infection.
CLINICAL CHARACTERISTICS
3/29/21
Houlding E, Mate K, Engler K, et al. | JMIR Mhealth Uhealth
Aim: To present the range of RMTs used in delivering care to COVID-19 patients and identify perceived benefits and barriers for their use.
INFECTION CONTROL
3/29/21
Abeldano RA, Coca SM, Abeldano GF, et al. | Ther Adv Respir Dis
Aim: To assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection.
UPDATED
CANDIDATE THERAPEUTICS
3/29/21
Gabbai-Armelin PR, de Oliveira AB, Ferrisse TM, et al. | Eur J Clin Invest
Aim: To review the evidence on the relation of COVID-19 and thrombotic events and identify prognostic factors.
UPDATED
CLINICAL CHARACTERISTICS
3/29/21
Papotsi E, Giannakoulis VG, Xourgia E, et al.  | Crit Care
Aim: To investigate the effect (if any) of timing of intubation on clinical outcomes of critically ill patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
3/29/21
Nahshon C, Segev Y, Schmidt M, et al. | J Chemother
Aim: To review the evidence on the outcomes of diagnosed COVID-19 cancer patients.
CLINICAL CHARACTERISTICS
3/29/21
Diaz-Arocutipa C, Branez-Condorena A, Hernande AV | Pharmacoepidemiol Drug Saf
Aim: To assess the prevalence and risk of QTc prolongation and arrhythmic events in COVID-19 patients treated with these drugs.
CANDIDATE THERAPEUTICS
3/29/21
Emile S, Hamid HKS, Khan SM, et al. | J Gastrointest Surg
Aim: To assess the extent of adoption, efficacy, and safety of NOM of acute appendicitis in the setting of COVID-19.
UPDATED
INFECTION CONTROL
3/29/21
Li Y, Ashcroft T, Chung A, et al. | J Glob Health
Aim: To synthesise all available evidence regarding the risk factors for poor outcomes in hospitalised COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/29/21
Gratz J, Miegele M, Maleczek M, et al. | Front Med
Aim: To provide robust estimates of clinically relevant VTE incidence rates in adult critically ill patients with COVID-19 together with estimates of bleeding rates.
CLINICAL CHARACTERISTICS
3/29/21
Brolin K, Cenciarelli O, Colzani E, et al. | European Centre for Disease Prevention and Control
Aim: To provide a summary of the available scientific evidence on the risk of SARS-CoV-2 transmission to susceptible contacts from infected individuals with documented previous infection or vaccination.
3/26/21
Cheng S, Zhao Y, Wang F, et al. | Medicine
Aim: To estimate the association of chronic comorbidities in severe and non-severe cases.
CLINICAL CHARACTERISTICS
3/26/21
Castiello T, Georgiopoulous G, Finocchiaro G, et al. | Heart Fail Rev
Aim: To review the challenges in the early diagnosis and management of myocarditis in patients with COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
3/26/21
Dubey P, Thakur B, Reddy S, et al. | BMC Pregnancy Childbirth
Aim: To review the evidence on any geographicaly differences in pregnant women with COVID-19.
CLINICAL CHARACTERISTICS
3/26/21
Johnson IG, Jones RJ, Gallagher JE, et al. | BDJ Open
Aim: To examine the literature relating to splatter, droplet settle and aerosol for periodontal procedures and forms part of a wider body of research to understand the risk of contamination in relation to periodontal care procedures relevant to COVID-19.
INFECTION CONTROL
3/26/21
Burns J, Movsisyan A, Stratil JM, et al. | Cochrane Database Syst Rev
Aim: To assess the effectiveness of travel?related control measures during the COVID?19 pandemic on infectious disease and screening?related outcomes.
UPDATED
WHO COLLABORATIVE
INFECTION CONTROL
3/26/21
Galanis P, Vraka I, Fragkou D, et al. | J Adv Nurs
Aim: To examine the impact of the COVID-19 pandemic on nurses’ burnout and to identify associated risk factors.
UPDATED
MENTAL HEALTH
3/26/21
Nugroho CW, Suryantror SD, Yuliasih Y, et al. | F1000Res
Aim: To research the risks and benefits of tocilizumab and investigate outcomes from different baseline criteria for administration of tocilizumab as a treatment for severe and critically ill COVID-19 patients.
CANDIDATE THERAPEUTICS
3/25/21
 | CADTH
3/25/21
Lai C, Chen C, Wang C, et al. | J Antimicrob Chemother
Aim: To provide updated information regarding the clinical efficacy of remdesivir in treating coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
3/25/21
Gerayeli FV, Milne S, Cheung C, et al. | EClinicalMedicine
Aim:  To determine whether COPD is a risk factor for poor outcomes in COVID-19, focusing on the specific endpoints of hospitalization, severe disease, and mortality.
UPDATED
CLINICAL CHARACTERISTICS
3/25/21
Antunes D, Lami M, Chukwudi A, et al. | Surgeon
Aim: To clarify whether inhalation of surgical smoke can increase the risk of COVID-19 infection.
INFECTION CONTROL
3/25/21
Kong X, Qi Y, Huang J, et al.  | Cancer Lett
Aim: To review the evidence on the prevalence of cancer in coronavirus disease 2019 (COVID-19)-infected patients and the severe illness incidence and mortality of COVID-19 patients with cancer.
UPDATED
CLINICAL CHARACTERISTICS
3/25/21
 | Pan American Health Organization
Aim: To review the evidence on potential COVID-19 therapeutics.
3/25/21
Hayashi Y, Wagatsuma K, Nojima M, et al. | J Gastroenterol
Aim: To undertake a systematic review and meta-analysis to determine whether the presence of gastrointestinal (GI) symptoms contributed toward COVID-19 severity, and identify the GI symptoms characteristic of severe COVID-19.
CLINICAL CHARACTERISTICS
3/24/21
Kasemi A, Mohammadi V, Aghababaee SK, et al. | Adv Nutr
Aim: To summarize and clarify the evidence on the association between 25(OH)D concentrations and COVID-19 risk and outcomes.
UPDATED
CLINICAL CHARACTERISTICS
3/24/21
Ghaderzadeh M, Asadi F | J Healthc Eng
Aim: To provide an overview of the current state of all models for the detection and diagnosis of COVID-19 through radiology modalities and their processing based on deep learning. 
DIAGNOSTICS
3/24/21
Almufarrij I, Munro K | Int J Audiol
Aim: To systematically review the literature to December 2020, in order to provide a timely summary of evidence on SARS-CoV-2, COVID-19 and audio-vestibular symptoms.
UPDATED
CLINICAL CHARACTERISTICS
3/24/21
Longchamp G, Manzocchi-Besson S, Longchamp A, et al. | Thromb J
Aim: To systematically review and meta-analyze the risk of clinically relevant VTE in patients hospitalized for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/24/21
So M, Kabata H, Fukunaga K, et al. | BMC Pulm Med
Aim: To clarify the characteristics of radiological and functional lung sequelae of COVID-19 patients described in follow-up period.
CLINICAL CHARACTERISTICS
3/24/21
De Simone B, Chouillard E, Sartelli M, et al. | World J Emerg Surg
Aim: To provide evidence-based recommendations for the management of emergency surgical patients under COVID-19 pandemic for the safety of the patient and healthcare workers.
INFECTION CONTROL
3/24/21
Raju R, V P, Biatris PS, et al. | Futur J Pharm Sci
Aim: To analyze various trials registered across the globe providing an overall picture of the use of corticosteroids in the treatment of COVID-19.
CANDIDATE THERAPEUTICS
3/23/21
Artusi CA, Romagnolo A, Ledda C, et al. | J Parkinsons Dis
Aim: To assess whether the prevalence and outcome of COVID-19 in PD patients are different from those observed in the general population.
CLINICAL CHARACTERISTICS
3/23/21
Prasad M, Seth T, Elavarasi A | Indian J Hematol Blood Transfus
Aim: To study the efficacy and safety of convalescent plasma in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
3/23/21
Peng J, Wang Q, Mei H, et al. | Aging
Aim: To investigate the association between fungal co-infection and mortality due to COVID-19.
CLINICAL CHARACTERISTICS
3/23/21
Masaeli N, Farhadi H | J Addict Dis
Aim: To find whether Internet-based addictive behaviors have increased during the pandemic and to define the main reasons for this increase.
MENTAL HEALTH
3/23/21
Kain D, Stall NM, Allen V, et al. | Science Table COVID-19 Advisory for Ontario
Aim: To review the evidence on routine asymptomatic screen testing of staff as a potential mitigating strategy to reduce SARS-CoV-2 introduction and transmission in LTC homes.
3/23/21
Tiruneh SA, Tesema ZT, Azanaw MM, et al. | Syst Rev
Aim: To assess the pooled incidence of COVID-19 complications and to identify the association between the incidence of complications and age.
UPDATED
CLINICAL CHARACTERISTICS
3/23/21
Teshome A, Adane A, Girma B, et al. | Front Public Health
Aim: To summarize the available evidence regarding the association between Vitamin D levels and the risk of COVID-19 infection.
CLINICAL CHARACTERISTICS
3/23/21
Ryan RE, Parkhill A, Schonfeld L, et al. | Health Evidence Network
Aim: To analyse evidence regarding communication with individuals and communities within the wider structural and sociopolitical context of the pandemic to support public health decision-makers when planning and implementing physical distancing measures.
WHO COLLABORATIVE
3/22/21
Menon T, Sharma R, Earthineni G, et al. | Cureus
Aim: To measure whether GI manifestations warrant the testing for SARS-CoV-2 alone or in combination with lung manifestations and the association of GI manifestations with severe disease and mortality. 
CLINICAL CHARACTERISTICS
3/22/21
Ssentongo P, Heilbrunn ES, Ssentongo A, et al. | Sci Rep
Aim: To conduct a systematic review and meta-analysis of the prevalence of HIV in patients hospitalized for COVID-19 and delineating clinical outcomes including mortality.
UPDATED
CLINICAL CHARACTERISTICS
3/22/21
Montazeri M, ZahediNasab R, Farahani A, et al. | JMIR Med Inform
Aim: To summarize information on the use of intelligent models for diagnosing and prognosing the COVID-19 to help early and timely diagnosis of the disease to help with health.
DIAGNOSTICS
3/22/21
Agarwal A, Fernando SM, Honarmand K, et al. | BMJ Open
Aim: To determine the risk of aerosol generation and associated transmission associated with nasopharyngeal and oropharyngeal swabs for detection of SARS-CoV-2.
INFECTION CONTROL
3/22/21
Zinellu A, Paliogiannis P, Carru C, et al. | Int J Infect Dis
Aim: To review the clinical implications of SAA concentrations in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/22/21
Dono F, Nucera B, Lanzone J, et al. | Epilepsy Behav
Aim: To summarize the available data on clinical features, diagnosis, and therapy of SE associated with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/22/21
Wei SQ, Bilodeau-Bertrand MB, Liu S, et al.  | CMAJ
Aim: To evaluate the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and adverse pregnancy outcomes.
CLINICAL CHARACTERISTICS
3/22/21
Zhao Y, Yin L, Jenil P, et al. | J Med Virol
Aim: To characterize inflammatory markers of MIS-C patients with COVID-19, Kawasaki disease (KD), and coronary artery abnormalities. 
UPDATED
CLINICAL CHARACTERISTICS
3/22/21
Barbalho SM, Matias JN, Flato UAP, et al. | Gastroenterology Res
Aim: To evaluate what influenza and COVID-19 may represent for patients with IBD.
CLINICAL CHARACTERISTICS
3/19/21
Welte T, Ambrose LJ, Sibbring GC, et al. | Eur Respir Rev
Aim: To identify clinical trials of pharmacological interventions for COVID-19 and evaluate for effectiveness.
UPDATED
CANDIDATE THERAPEUTICS
3/19/21
Zhang XM, Jiao J, Cao J, et al. | BMC Geriatr
Aim: To systematically review and quantify the results of the associations between frailty and mortality.
UPDATED
CLINICAL CHARACTERISTICS
3/19/21
Ghosn L, Chaimani A, Evrenoglou T, et al. | Cochrane Database Syst Rev
Aim: To assess the effect of IL?6 blocking agents compared to standard care alone or with placebo on efficacy and safety outcomes in COVID?19.
UPDATED
CANDIDATE THERAPEUTICS
3/18/21
Kalin A, Javid B, Knight M, et al. | Syst Rev
Aim: To summarise the literature on the performance of different rapid tests for exertional desaturation.
UPDATED
DIAGNOSTICS
3/18/21
Karimi L, Makvandi S, Vahedian-Azimi A, et al. | J Pregnancy
Aim: To investigate the effects of coronavirus disease 2019 (COVID-19) on mortality of pregnant and postpartum women.
CLINICAL CHARACTERISTICS
3/18/21
Moynihan R, Sanders S, Michaleff Z, et al.  | BMJ Open
Aim: To determine the extent and nature of changes in utilisation of healthcare services during COVID-19 pandemic. 
UPDATED
INFECTION CONTROL
3/18/21
Cares-Marambio K, Montenegro-Jimenez Y, Torres-Castro R, et al. | Chron Respir Dis
Aim: To determine the prevalence of respiratory symptoms in survivors of hospital admission after COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
3/18/21
Giovanella L, Ruggeri RM, Ovcaricek PP, et al. | Clin Transl Imaging
Aim: To assess the prevalence of thyroid dysfunction in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/18/21
Hassib M, Hamilton S, Elkhouly A, et al. | Cureus
Aim: To assess whether ACEi/ARB use in patients with COVID-19 conferred worsened severity of illness or increased mortality.
CLINICAL CHARACTERISTICS
3/18/21
Shi S, Wang F, Li J, et al. | IUBMB Life
Aim: To test the efficacy of CHM on digestive symptoms and liver function (primary outcomes), the aggravation of COVID-19 and the time to viral assay conversion (secondary outcomes), among patients with COVID-19, compared with standard pharmacotherapy.
CANDIDATE THERAPEUTICS
3/18/21
Kazemi E, Nejat RS, Ashkan F, et al. | Ann Clin Microbiol Antimicrobiol
Aim: To show the differences of laboratory findings of COVID-19 patients with different severity and survivability who had been admitted in hospital.
CLINICAL CHARACTERISTICS
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the AstraZeneca vaccine and blood clots.
3/17/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidenceo n the likelihood that SARS-CoV-2 will become endemic.
3/17/21
Grepin KA, Ho T, Liu Z, et al. | BMJ Glob Health
Aim: To review evidence of the effectiveness of travel measures implemented during the early stages of the COVID-19 pandemic in order to recommend change on how evidence is incorporated in the International Health Regulations (2005) (IHR).
UPDATED
INFECTION CONTROL
3/17/21
Lebrasseur A, Fortin-Bedard N, Lettre J, et al.  | JMIR Aging
Aim: To synthesize the existing research on the impact of the COVID-19 pandemic, and associated isolation and protective measures, on older adults. 
UPDATED
MENTAL HEALTH
3/17/21
Robinson E, Jones A, Lesser I, et al. | Vaccine
Aim: To address the current lack of consensus on; i) the proportion of the population willing to be vaccinated against COVID-19 when a vaccine become available and how this differs across countries, ii) whether vaccination intentions have declined as the pandemic has progressed, iii) socio-demographic inequalities in intended vaccine uptake.
UPDATED
INFECTION CONTROL
3/17/21
Wang Z, Wang D | Int J Soc Psychiatry
Aim: To reveal the law of formation of public psychological crisis in public health emergencies, and draw lessons from it.
MENTAL HEALTH
3/16/21
Kaur A, Setia AS, Kashyap A, et al. | Eur J Mol Clin Med
Aim: To highlight the existing literature and organize data associating the mortality of coronavirus disease 2019 (COVID-19) in patients with and without asthma.
CLINICAL CHARACTERISTICS
3/16/21
Meena JP, Gupta AK, Tanwar P, et al. | Pediatr Blood Cancer
Aim: To review the evidence on pediatric cancer patients affected by COVID-19 and analyze the clinical manifestations and outcomes.
UPDATED
3/16/21
Hariyanto TI, Halim DA, Jodhinata C, et al. | Clin Exp Pharmacol Physiol
Aim: To analyze the efficacy of colchicine administration and outcomes of COVID-19. 
CANDIDATE THERAPEUTICS
3/16/21
Dalia T, Lahan S, Ranka S, et al. | Indian Heart J
Aim: To delineate the influence of various cardiac conditions (especially CHF) on outcomes of patients with COVID-19 and to determine the prognostic value of cardiac biomarkers — Troponin I, Creatine Kinase-MB (CK-MB), and N-terminal-proB-type Natriuretic Peptide (NT-proBNP).
CLINICAL CHARACTERISTICS
3/16/21
Munich J, Dennett L, Swainson J, et al. | Front Psychiatry
Aim: To rapidly synthesize available data on emergency department utilization for psychiatric concerns during COVID-19.
3/16/21
Bokharee N, Khan YH, Khokhar A, et al. | Expert Rev Anti Infect Ther
Aim: To systematically analyze the published and ongoing studies evaluating the pharmacological interventions for COVID-19.
CANDIDATE THERAPEUTICS
3/16/21
Helvaci N, Eyupoglu ND, Karabulut E, et al.  | Front Endocrinol
Aim: To evaluate the prevalence of obesity in patients with COVID-19 and to stratify the estimates by illness severity.
UPDATED
3/16/21
Hossain A, Nasrullah SM, Tasnim Z, et al. | EClinicalMedicine
Aim: To estimate pooled seroprevalence of SARS-CoV-2 IgG antibodies across geographic regions and to investigate the pattern by age-group, gender, infection risk of HCWs, and study period.
UPDATED
3/16/21
da Silva FCT, Barbosa CP | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To understand the impact that COVID-19 is having on the front-line clinical team in the ICU environment, as well as reveal what proposals are being made to mitigate the clinical and psychological impacts that this group experiences.
3/15/21
Mehta AA, Haridas N, Belgundi P, et al. | Diabetes Metab Syndr
Aim: To provide a comprehensive summary of clinical and laboratory parameters that are associated with and indicative of increased severity among COVID-19 patients.
3/15/21
Marzoli F, Bortolami A, Pezzuto A, et al. | Sci Total Environ
Aim: To summarize all the evidence on surface survival of coronaviruses infecting humans. 
3/15/21
Lim ZJ, Reddy MP, Curtis JR, et al. | Crit Care Med
Aim: To investigate the incidence, characteristics, and outcomes of in-hospital cardiac arrest in patients with coronavirus disease 2019 and to describe the characteristics and outcomes for patients with in-hospital cardiac arrest within the ICU, compared with non-ICU patients with in-hospital cardiac arrest. 
UPDATED
3/15/21
Huntley B, Mulder IA, Di Mascio D, et al. | Obstet Gynecol
Aim: To compare the risk of intrauterine fetal death (20 weeks of gestation or later) and neonatal death among individuals who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with those who tested negative for SARS-CoV-2 on admission for delivery.
UPDATED
3/15/21
Mackey K, Arkhipova-Jenkins I, Armstrong C, et al. | Agency for Healthcare Research and Quality
Aim: To synthesize evidence on the prevalence, levels, and durability of the antibody response to SARS-CoV-2 infection among adults and how antibodies correlate with protective immunity.
CLINICAL CHARACTERISTICS
3/15/21
Karimian M, Azami M | Pol J Radiol
Aim: To evaluate CT scan findings of COVID-19 at the time of admission.
UPDATED
3/15/21
Allotey J, Stallings E, Bonet M, et al. | BMJ
Aim: To determine the clinical manifestations, risk factors, and maternal and perinatal outcomes in pregnant and recently pregnant women with suspected or confirmed coronavirus disease 2019 (covid-19).
UPDATED
CLINICAL CHARACTERISTICS
3/15/21
Yang Y, Sun S, Hu S, et al. | Front Psychol
Aim: To compare the different psychological interventions and distinguish the most effective way to treat psychological crisis according to different clinical manifestations in people affected by coronavirus disease 2019 (COVID-19).
3/15/21
Zhang X, Xi L, Pang F, et al. | Iran J Public Health
Aim: To summarize the clinical evidence regarding the efficacy and safety of convalescent plasma therapy in the treatment of severe COVID-19.
3/15/21
Qiang Z, Wang B, Garrett BC, et al. | Curr Opin Cardiol
Aim: To have a greater mortality impact on subgroups of people in the population who are deemed to be at higher medical disease risk.
3/15/21
Pranata R, Huang I, Lim MA, et al. | Arch Gerontol Geriatr
Aim: To establish the association between delirium and mortality in older adults with COVID-19.
UPDATED
3/15/21
Xing K, Tu X, Liu M, et al. | Zhongguo Dang Dai Er Ke Za Zhi
Aim: To evaluate systematically the efficacy and safety of COVID-19 vaccines.
3/15/21
Abate SM, Checkol YA, Mantefardo B | Ann Med Surg
Aim: To provide global evidence on the prevalence and risk factors including age, gender, comorbidity, and substance use on hospital mortality among hospitalized patients with COVID-19.
3/15/21
Syahrul S, Maliga HA, Ilmawan M, et al. | F1000Research
Aim: To determine the global prevalence, chronological order of symptom appearance, and mortality rates with regard to hemorrhagic and ischemic stroke in patients with coronavirus disease 2019 (COVID-19) and to discuss possible pathogeneses of hemorrhagic and ischemic stroke in individuals with the disease.
UPDATED
3/15/21
Juul S, Nielsen N, Feinberg J, et al. | PLoS Med
Aim: To compare the effects of all treatment interventions for participants in all age groups with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
3/15/21
Yuan J, Qian H, Cao S, et al. | Transl Pediatr
Aim: To investigate the clinical features of pregnant women and their neonates with coronavirus disease 2019 (COVID-19) and the evidence of vertical transmission of COVID-19.
3/15/21
Moran C, Campbell DJT, Campbell TS, et al. | J Public Health
Aim: To identify predictors of attitudes toward and adherence to COVID-19 public health guidelines, and identify interventions aiming to improve adherence.
3/15/21
Alene M, Yismaw L, Assemie MA, et al. | BMC Infect Dis
Aim: To determine the overall pooled mean serial interval and incubation period of COVID-19 using available evidences.
3/15/21
Dorward J, Gbinigie O, Cai T, et al. | Antivir Ther
Aim: To synthesise the clinical evidence for lopinavir/ritonavir as a treatment for COVID-19.
3/15/21
Stanoeva KR, van der Eijk AA, Meijer A, et al. | Euro Surveill
Aim: To review current published knowledge on the kinetics of SARS-CoV-2 infection as assessed by RNA molecular detection in a wide range of clinical samples.
3/12/21
Oltean I, Tran J, Lawrence S, et al. | Heliyon
Aim: To illustrate findings in a narrative fashion pertaining to SARS-CoV-2 on placental pathology, maternal, and neonatal outcomes.
UPDATED
CLINICAL CHARACTERISTICS
3/12/21
Jafari A, Mohammadpour M, Chanbarzadegan A, et al. | J Educ Health Promot
Aim: To review the literature to provide a better understanding of the status of dentists and other oral health practitioners' knowledge, attitude, and awareness about COVID-19.
INFECTION CONTROL
3/12/21
Sharma D, Sharma N, Sharma P, et al. | J Educ Health Promot
Aim: To discuss about investigational new as well as repurposed drugs currently under trial for COVID-19 infection.
CANDIDATE THERAPEUTICS
3/11/21
Pellicori P, Doolub G, Wong CM, et al. | Cochrane Database Syst Rev
Aim: To assess the prevalence of pre?existing cardiovascular comorbidities associated with suspected or confirmed cases of COVID?19 in a variety of settings, including the community, care homes and hospitals. 
UPDATED
CLINICAL CHARACTERISTICS
3/11/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the effectiveness of the AstraZeneca vaccine, particuarly regarding hospitalisations in the United Kingdom.
3/11/21
Alkhathami M, Advani SM, Abalkhail AA, et al. | Lung India
Aim: To determine the prelavence and mortality of chronic lung diseases which include COPD, lung cancer, asthma, and cystic fibrosis in confirmed COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
3/11/21
Wang Q, Liu J, Shao R, et al.  | Rheumatol Int
Aim: To integrate data on the epidemiology of COVID-19 in the RD population and to analyze the risk of COVID-19 infection and its complications in RD patients compared with the general population.
UPDATED
CLINICAL CHARACTERISTICS
3/11/21
Cruciani F, Amato L, De Crescenzo F, et al. | Recenti Prog Med
Aim: To synthesize and evaluate the quality of evidence of efficacy and safety for the treatment. 
CANDIDATE THERAPEUTICS
3/10/21
Kumar P, Jindal K, Aggarwal S, et al. | Indian J Orthop
Aim: To ascertain the impact of a co-existent infection on the 30-day mortality and inpatient mortality of patients with hip fractures including neck femur, intertrochanteric and subtrochanteric fractures. 
CLINICAL CHARACTERISTICS
3/10/21
Osman M, Klopfenstein T, Belfeki N, et al. | Viruses
Aim: To compare the clinical features and outcome, laboratory, and radiological findings of COVID-19 patients with influenza adult patients.
CLINICAL CHARACTERISTICS
3/10/21
Cai J, Tang M, Gao Y, et al. | Front Med
Aim: To determine which mode of delivery is better for preventing possible vertical transmission from COVID-19 positive pregnant women to the neonate.
UPDATED
INFECTION CONTROL
3/10/21
Pal R, Banerjee M, Mukherjee S, et al. | Ther Adv Endocrinol Metab
Aim: To provide a precise summary of the effect of DPP4i use (preadmission or in-hospital) and mortality in COVID-19 patients with diabetes mellitus (DM).
UPDATED
CLINICAL CHARACTERISTICS
3/10/21
Meena J, Jain S, Kumar j, et al.  | J Infect Chemother
Aim: To systematically synthesize the evidence over the efficacy and safety of HCQ or CQ alone as compared to placebo or no active intervention in adults with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
3/10/21
Hashan MR, Smoll N, King C, et al. | EClinicalMedicine
Aim: To define the epidemiology of COVID-19 outbreaks in RACFs to estimate the epidemiological index of the disease for these vulnerable populations.
UPDATED
CLINICAL CHARACTERISTICS
3/10/21
Gawronska K, Lorkowski J | Geriatr Orthop Surg Rehabil
Aim: To present the possible correlation between COVID-19 and diseases of the musculoskeletal system, in particular the occurrence of fall-related injuries.
CLINICAL CHARACTERISTICS
3/10/21
SeyedAlinaghi S, Afsahi AM, MohsseniPour M, et al. | Arch Acad Emerg Med
Aim: To investigate the available evidence for long-term complications of COVID-19.
CLINICAL CHARACTERISTICS
3/10/21
Chou R, Dana T, Jungbauer R, et al. | Ann Intern Med
Aim: To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.
UPDATED
3/10/21
Li Y, Scherer N, Felix L, et al. | PLoS ONE
Aim: To provide updated estimates of the prevalence of depression, anxiety and post-traumatic stress disorder (PTSD) among health care workers during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/10/21
Xia L, Chen C, Liu Z, et al. | Front Psychiatry
Aim: To explore the prevalence of sleep disturbances and sleep quality in Chinese HWs during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/10/21
Gallastegui N, Zhou JY, von Drygalski A, et al. | Clin Appl Thromb Hermost
Aim: To estimate the incidence of PE during hospitalization for COVID19 within and outside ICUs.
CLINICAL CHARACTERISTICS
3/9/21
Piquero AR, Jennings WG, Jemison E, et al. | J Crim Justice
Aim: To estimate the effect of COVID-19-related restrictions (i.e., stay at home orders, lockdown orders) on reported incidents of domestic violence.
MENTAL HEALTH
3/9/21
Veazie S, O'Neil M, LaFavor B, et al.  | VA Evidence Synthesis Program
Aim: To compare the prevalence of mental health disorders among adults who have been hospitalized for COVID-19 to relevant comparison groups, assess whether the prevalence of mental health disorders varies by patient and disease characteristics, and ascertain mental health care utilization and resource needs for adults following hospitalization for COVID-19.
UPDATED
VA ESP
MENTAL HEALTH
3/9/21
Deng J, Zhou F, Hou W, et al. | Psychiatry Res
Aim: To examine the prevalence of depressive symptoms, anxiety symptoms, and sleep disturbances in higher education students to better understand the impact of the COVID-19 pandemic on the mental health of higher education students.
UPDATED
MENTAL HEALTH
3/8/21
Ho TC, Wang YH, Chen YL | Pathogens
Aim: To synthesize articles regarding the cure of COVID-19 by CQ or HCQ and depict the efficacy of these drugs for COVID-19 treatment.
CANDIDATE THERAPEUTICS
3/8/21
Macedo A, Gonçalves N, Febra C, et al. | Ann Epidemiol
Aim: To evaluate the mortality of COVID-19.
CLINICAL CHARACTERISTICS
3/8/21
DiLorenzo MA, O'Connor S, Ezekwesili C, et al. | Int J Gynaecol Obstet
Aim: To summarize recommendations for three areas of maternal and fetal care - breastfeeding, post-partum social distancing, and decontamination.
INFECTION CONTROL
3/8/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the impact of the COVID-19 pandemic on the publication of pre-peer review articles and the quality of research evidence.
3/8/21
Peddapalli A, Gehani M, Kalle AM, et al. | Viruses
Aim: To review various mechanisms of excess immune response in adult COVID-19 patients
CLINICAL CHARACTERISTICS
3/8/21
Moreira VM, Mascarenhas P, Machado V, et al. | Diagnostics
Aim: To compare the overall accuracy of nucleic acid assays run with index specimens (saliva, deep-throat saliva/posterior oral samples (DTS/POS], sputum, urine, feces, and tears/CS), against standard NPS/OPS based test results.
DIAGNOSTICS
3/8/21
Johnson T, Bishoff T, Kremsreiter K, et al. | Med J
Aim: To perform a systematic review of the literature and to provide evidence-based algorithms for diagnosing or ruling out COVID-19.
DIAGNOSTICS
3/8/21
Sarma P, Bhattacharyya A, Kaur H, et al. | Indian J Pharmacol
Aim: To evaluate the efficacy and safety of steroid therapy among all severity categories of patients with COVID-19 (mild to moderate and severe to critical category) in terms of "mortality," "requirement of mechanical ventilation," "requirement of ICU" and clinical cure parameters.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Shehab M, Alrashed F, Shuaibi S, et al. | BMJ Open Gastroenterol
Aim: To evaluate the prevalence of GI, liver function test (LFT) abnormalities, and mortality of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Boldt K, Coenen M, Movsisyan A, et al. | Int J Environ Res Public Health
Aim: To identify interventions that target children, their caregivers and/or families, in order to reduce the psychosocial impacts caused by the COVID-19 and comparable disease outbreaks, as well as associated control measures (e.g., quarantine).
MENTAL HEALTH
3/8/21
Cordeiro LP, Linhares EONN, Nogueira FGO, et al. | Pharmacol Rep
Aim: To systematically review the studies that described the use of GC in patients with COVID-19 and to provide a safer analysis of the effectiveness and recommendations for GC use.
CANDIDATE THERAPEUTICS
3/8/21
Booth A, Reed AB, Ponzo S, et al. | PLoS One
Aim: To systematically map all the available evidence on the association of various clinical, demographic, and lifestyle variables with the risk of specific adverse outcomes in patients with COVID?19.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Sansone P, Giaccari LG, Aurilio C, et al. | Life
Aim: To give a comprehensive overview of the demographic characteristics, clinical features, diagnostic investigations, and outcome of SARS-CoV-2-related GBS patients. 
CLINICAL CHARACTERISTICS
3/8/21
Al Falasi B, Al Mazrouei M, Al Ali M, et al. | Int J Environ Res Public Health
Aim: To investigate the prevalence and determinants of immediate and long-term post-traumatic stress disorder (PTSD) effects on healthcare professionals by the COVID-19 (SARS CoV-2) and SARS-2003 (SARS CoV-1) pandemics.
MENTAL HEALTH
3/8/21
Jamshidi P, Hajikhani B, Mirsaeidi M, et al. | Front Med
Aim: To investigate the prevalence and characteristics of cutaneous manifestations in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
3/8/21
Skapetis T, Law C, Rodricks R, et al. | BMC Med Ethics
Aim: To determine the ethical challenges associated with conducting medical research in low COVID-19 prevalence countries.
3/8/21
Wibowo A, Pranata R, Akbar MR, et al. | Int J Infect Dis
Aim: To assess the prognostic value of elevated troponin above the 99th percentile upper reference limit (URL) on mortality and factors affecting their relationship.
CLINICAL CHARACTERISTICS
3/8/21
Akbar MR, Pranata R, Wibowo A, et al. | Diabetes Metab Syndr
Aim: To evaluate the association between the elevated CK and severity and mortality in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/7/21
Tondas AE, Mulawarman R, Trifitriana M, et al. | J Infect Dev Ctries
Aim: To investigate the electrocardiographic (ECG) ventricular repolarization indices in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/6/21
Li Z, Li X, Shen J, et al. | Environ Sci Pollut Res Int
Aim: To systematically review case reports on COVID-19-associated MFS, including the electrophysiological and clinical phenotypes.
CLINICAL CHARACTERISTICS
3/5/21
Sinclair JE, Zhu Y, Xu G, et al. | iScience
Aim: To analyze the association of host co-morbidities (chronic respiratory illnesses, cardiovascular disease [CVD], hypertension or diabetes mellitus [DM]) with the acute cardiovascular complications associated with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
3/5/21
Vahedian-Azimi A, Karimi L, Makvandi S, et al. | Adv Exp Med Biol
Aim: To investigate whether the causative agent of COVID-19 is found in semen. 
CLINICAL CHARACTERISTICS
3/5/21
Zhan Y, Shang J, Gu Y, et al. | J Med Virol
Aim: To evaluate the efficacy of corticosteroids on COVID-19 patients with different levels of disease severity.
CANDIDATE THERAPEUTICS
3/5/21
Schumm MA, Hadaya JE, Mody N, et al. | JAMA
Aim: To perform a systematic review to evaluate the evidence on effectiveness and feasibility of different processes used for decontaminating N95 respirators.
INFECTION CONTROL
3/5/21
Sheth A, Modi M, Dawson D, et al. | Sci Rep
Aim: To summarize the evidence regarding the prognostic relevance of cardiac biomarkers from data available in published reports.
CLINICAL CHARACTERISTICS
3/5/21
Makvandi S, Mahdavian M, Kazemi-Nia G, et al. | Adv Exp Med Biol
Aim: To report clinical symptoms, laboratory findings, and obstetrical complications, maternal, fetal, and neonatal complications of COVID-19 infection in pregnant women.
CLINICAL CHARACTERISTICS
3/5/21
Heidari-Beni F, Vahedian-Azimi A, Shojaei S, et al. | Adv Exp Med Biol
Aim: To investigate PCT levels in severe COVID-19 patients.
CLINICAL CHARACTERISTICS
3/5/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on how long the COVID-19 virus can survive with potential for infection on surfaces found in community settings.
3/4/21
Strudwick G, Sockalingam S, Kassam I, et al. | JMIR Ment Health
Aim: To identify digital interventions that could be used to support the mental health of the Canadian general population during the COVID-19 pandemic. 
MENTAL HEALTH
3/4/21
Park JY, Freer R, Stevens R, et al.  | Oxford COVID-19 Evidence Service
3/4/21
Yang Y, Luo K, Jiang Y, et al. | J Nutr Health Aging
Aim: To synthesize the current studies to investigate impact of frailty on COVID-19 outcomes and provide evidence-based decisions in clinical practice.
CLINICAL CHARACTERISTICS
3/3/21
Jones EAK, Mitra AK, Bhuiyan AR | Int J Environ Res Public Health
Aim: To assess the impact of the COVID-19 pandemic on adolescent mental health.
MENTAL HEALTH
3/2/21
Simons D, Shahab L, Brown J, et al. | Addiction
Aim: To estimate the association of smoking status with rates of i) infection, ii) hospitalisation, iii) disease severity, and iv) mortality from SARS?CoV?2/COVID?19 disease.
UPDATED
CLINICAL CHARACTERISTICS
3/1/21
Raphael J, Winter R, Berry K | BJPsych Open
Aim: To explores service adaptations in mental health services during the COVID-19 pandemic and other contagions.
INFECTION CONTROL
3/1/21
Diallo A, Carlos-Bolumbu M, Traore M, et al. | J Public Health Res
Aim: To compare and rank the efficacy and safety of treatments tested in patients with SARSCoV- 2 virus.
UPDATED
CANDIDATE THERAPEUTICS
3/1/21
Janiaud P, Axfors C, Schmitt AM, et al. | JAMA
Aim: To assess clinical outcomes with convalescent plasma treatment vs placebo or standard of care in peer-reviewed and preprint publications or press releases of randomized clinical trials (RCTs).
CANDIDATE THERAPEUTICS
3/1/21
Sahranavard M, Rezayat AA, Bidary MZ, et al. | Arch Iran Med
Aim: To review the evidence on cardiac complications in patients with COVID-19.
CLINICAL CHARACTERISTICS
3/1/21
Liang C, Zhang W, Li S, et al. | Med Clin
Aim: To search the association between coronary heart disease and the prognosis of COVID-19 patients.
CLINICAL CHARACTERISTICS
3/1/21
Willi S, Luthold R, Hunt A, et al. | Travel Med Infect Dis
Aim: To evaluate the available evidence of all intermediate and long-term COVID-19 sequelae affecting formerly healthy adults.
CLINICAL CHARACTERISTICS
3/1/21
Toba N, Gupta S, Ali AY, et al. | Pediatr Pulmonol
Aim: To understand the clinical characteristics of COVID-19 in children.
CLINICAL CHARACTERISTICS
3/1/21
Zhou X, Pu Y, Zhang D, et al. | Acta Radiol
Aim: To explore the chest CT findings and dynamic CT changes of COVID-19 using systematic evaluation methods, instructing the clinical imaging diagnosis.
DIAGNOSTICS
3/1/21
Yang L, Chai P, Yu J, et al. | Cancer Biol Med
Aim: To investigate cancer incidence in patients with COVID-19 and to determine whether cancer was associated with mortality among patients with COVID-19.
CLINICAL CHARACTERISTICS
3/1/21
Gupta N, Balcom S, Gulliver A, et al. | Int J Health Planning Manag
Aim: To assess the state of the evidence on policy and planning responses to HRH surge capacity during the coronavirus disease (COVID?19) pandemic and other viral respiratory disease outbreaks of global significance in the 21st century.
UPDATED
3/1/21
Zang S, Han X, Cui Q, et al. | Transl Pediatr
Aim: To summarize a comprehensive review and meta-analysis with a complete evaluation of CT characteristics in pediatric COVID-19 cases. 
UPDATED
DIAGNOSTICS
3/1/21
Samadder S | Front Public Health
Aim: To identify the possible cause of secondary pneumonia infection observed in COVID-19 patients.
CLINICAL CHARACTERISTICS
3/1/21
Tassone D, Thompson A, Connell W, et al. | Intern Med J
Aim: To determine whether immunosuppressed patients are at higher risk of COVID-19 to help inform the management of patients receiving immunosuppressant therapies during the pandemic.
CLINICAL CHARACTERISTICS
3/1/21
Zhou X, Cheng Z, Luo L, et al. | Thromb Res
Aim: To evaluate the prevalence of disseminated intravascular coagulation (DIC) in COVID-19 patients and to determine the association of DIC with the severity and prognosis of COVID-19.
CLINICAL CHARACTERISTICS
3/1/21
Fan FC, Zhang SY, Cheng Y | J Epidemiol Community Health
Aim: To evaluate the updated psychological prevalence of COVID-19 and historical coronavirus-related data.
MENTAL HEALTH
3/1/21
Tang Y, Li W, Baskota M, et al. | Transl Pediatr
Aim: To describe the clinical features, treatment and outcomes of MIS-C, as well as to assess the risk of bias of published case studies, analyzing their reporting quality.
CLINICAL CHARACTERISTICS
3/1/21
Poly TN, Islam M, Yang HC, et al. | Front Med
Aim: To evaluate the effect of obesity, associated comorbidities, and other factors on the risk of death due to COVID-19. 
CLINICAL CHARACTERISTICS
3/1/21
Aghili SMM, Ebrahimpur M, Arjmand B, et al. | Int J Obes
Aim: To clarify the obesity relationship with COVID-19 severity, comorbidities, and discussing possible mechanisms.
CLINICAL CHARACTERISTICS
3/1/21
Goodwin VA, Allan L, Bethel A, et al. | Physiotherapy
Aim: To establish the evidence for rehabilitation interventions tested in populations of patients admitted to ICU and critical care with severe respiratory illness, and consider whether the evidence is generalizable to patients with COVID-19.
CANDIDATE THERAPEUTICS
3/1/21
Canete MG, Valenzuela IM, Garces PC, et al. | Oral Surg Oral Med Oral Pathol Oral Radiol
Aim: To describe the value of saliva as a noninvasive sample for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in comparison with the current method for sample collection, the nasopharyngeal swab.
DIAGNOSTICS
3/1/21
Barlow-Pay F, Htut TW, Khezrian M, et al. | Ther Adv Drug Saf
Aim: To summarize the current international clinical guidelines to highlight areas where research is needed through critical appraisal of the evidence base of these guidelines.
CLINICAL CHARACTERISTICS
3/1/21
Alom S, Chiu CM, Jha A, et al. | Cancer Control
Aim: To gather primary data from cancer institutions that have implemented changes to cancer service provision amid the COVID-19 outbreak to inform future intervention and health care facility response strategies. 
INFECTION CONTROL
3/1/21
Naveed H, Elshafeey A, Al-Ali D, et al. | J Clin Pharmcol
Aim: To compare specific blood markers in both groups of COVID-19 patients in order to gain a better insight into the interaction of ACEi/ARBs with the different body functions during the infection.
CLINICAL CHARACTERISTICS
3/1/21
Sabe M, Dorsaz O, Hugguelet P, et al. | Gen Hosp Psychiatry
Aim: To review clinical evidence regarding the potential toxicity/side effects of psychiatric medications in the context of SARS-CoV-2 infection.
CANDIDATE THERAPEUTICS
2/28/21
Karruli A, Spiezia S, Boccia F, et al. | Transpl Infect Dis
Aim: To assess the effect of continuing immune suppressive therapy in solid organ transplant recipients (SOTR) with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/28/21
 | Penn Medicine’s Center for Evidence-based Practice
Aim: To identify pathways, algorithms, and clinical risk prediction tools that can be used in Emergency Department triage of patients with suspected or confirmed COVID-19 disease and to review the evidence on their effectiveness.
2/26/21
Tan BK, Mainbourg S, Friggeri A, et al. | Thorax
Aim: To review the evidence on the prevalence of venous thromboembolic event (VTE) and arterial thromboembolic event (ATE) thromboembolic events in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/26/21
Liang S, Zhang Y, Shen C, et al. | Front Pharmacol
Aim: To further probe the role of CHM used with or without conventional western therapy on the treatment of COVID-19.
CANDIDATE THERAPEUTICS
2/26/21
Ernawati K, Cantika IB, Isaputri RR, et al. | Int J Public Health Sci
Aim: To determine the community's knowledge, attitudes, and behavior in preventing the transmission of COVID-19.
INFECTION CONTROL
2/26/21
Aibakr AA, Ingle NA, Assery MK, et al. | Ann Med Health Sci Res
Aim: To identify the role of corticosteroids on coronavirus infection and to compare the mortality and morbidity rate of steroid intervened corona virus infected patients.
CANDIDATE THERAPEUTICS
2/26/21
Sun C, Chen Y, Hu L, et al.  | Dig Dis Sci
Aim: To assess effects of famotidine on improving the outcome of those suffered COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
2/26/21
Mishra P, Parveen R, Bajpai R, et al. | Ann Acad Med Singap
Aim: To find the probable association between cardiovascular disease with disease severity and mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/26/21
Bentivegna M, Hulme C, Ebell MH | J Am Board Fam Med
Aim: To summarize the best available evidence regarding individual risk factors, simple risk scores, and multivariate models that use patient characteristics, vital signs, comorbidities, and laboratory tests in inpatients.
UPDATED
CLINICAL CHARACTERISTICS
2/26/21
Benzinger P, Kuru S, Keilhauer A, et al. | Z Gerontol Geriatr
Aim: To review the evidence on the psychosocial effects of the COVID-19 pandemic on residents, visitors, and employees of elderly care facilities.
MENTAL HEALTH
2/26/21
Hurtado-Diaz M, de la Cruz JC, Blanco-Munoz J, et al. | Salud Publica de Mexico
Aim: To summarize and analyze the evidence of the association between Covid-19 and climatic factors. 
CLINICAL CHARACTERISTICS
2/25/21
Zhang H, Ma S, Han T, et al. | Eur J Integr Med
Aim: To review the evidence on the influence of smoking history on the severe and critical outcomes on people with COVID-19 pneumonia.
CLINICAL CHARACTERISTICS
2/25/21
McAlpine LS, Fesharaki-Zadeh A, Spusich S | Curr Opin Psychiatry
Aim: To review the outcomes in patients with COVID-19 and NDD.
CLINICAL CHARACTERISTICS
2/25/21
Yin TX, Li Y, Ying Y, et al. | BMC Infect Dis
Aim: To provide systematic evaluation and detailed estimation of prevalence rates of different kinds of common comorbidities in severe and non-severe COVID-19 patients and tries to illustrate the outcomes by combination with underlying pathogenesis to better understand how basic diseases contribute to the aggravation of SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
2/25/21
Struyf T, Deeks JJ, Dinnes J et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of signs and symptoms to determine if a person presenting in primary care or to hospital outpatient settings, such as the emergency department or dedicated COVID?19 clinics, has COVID?19 disease or COVID?19 pneumonia.
UPDATED
DIAGNOSTICS
2/25/21
Ng JJ, Liang ZC, Choong A | J Intensive Care
Aim: To quantitatively synthesize available literature by using meta-analysis of proportions to estimate the weighted average incidence of PTE in critically ill COVID-19 patients admitted to the intensive care unit (ICU).
UPDATED
CLINICAL CHARACTERISTICS
2/25/21
Schiff JW | CMH Initiative
2/24/21
Jamebozorgi AH, Agoush L, NooriHekmat S, et al. | Research Square
Aim: To systematically review the challenges and prerequisites, strategies, and measures related to the retention of health workers during the disaster.
MENTAL HEALTH
2/24/21
Corona G, Pizzocaro A, Vena W, et al. | Rev Endocr Metab Disord
Aim: To provide an overview and a meta-analysis of main predictors and of country differences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-associated mortality rate (MR) in hospitalized patients. 
UPDATED
CLINICAL CHARACTERISTICS
2/24/21
Ma S, Xu C, Liu S, et al. | Signal Transduct Target Ther
Aim: To address the efficacy and safety of corticosteroids among severe COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/24/21
Widyadharma IPE, Hendellyn A, Dewi A | Egypt J Neurol Psychiatr Neurosurg
Aim: To briefly review neurologic manifestation in COVID-19 infection in the Asia region (South East Asia and the Western Pacific Region).
CLINICAL CHARACTERISTICS
2/24/21
Bulfone TC, Malekinejad M, Rutherford GW, et al. | J Infect Dis
Aim: To quantify the risk of SAR-CoV-2 transmission in outdoor settings. 
UPDATED
INFECTION CONTROL
2/24/21
Martins MM, Prata-Barbosa A, da Cunha AJLA | Paediatr Int Child Health
Aim: To review the evidence on clinical presentations, ways of transmission, severity and prognosis of SARS-CoV-2 infection in children and adolescents.
CLINICAL CHARACTERISTICS
2/23/21
Avianai JK, Halim D, Soeroto AY, et al. | Rev Med Virol
Aim: To evaluate CPT potentials in COVID-19 treatment, by performing systematic review and meta-analysis of studies in COVID-19 and other similar viral respiratory diseases, including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS) and Influenza.
UPDATED
CANDIDATE THERAPEUTICS
2/23/21
 | CADTH
Aim: To review the evidence on tocilizumab and sarilumab for their potential use in managing COVID-19.
2/22/21
Conrado PCV, Sakita KM, Arita GS, et al. | Photodiagnosis Photodyn Ther
Aim: To assess whether photodynamic therapy and its mechanisms of action could be effective in inactivating SARS-CoV-2.
CANDIDATE THERAPEUTICS
2/22/21
Soheili M, Moradi G, Baradaran HR, et al. | J Matern Fetal Neonatal Med
Aim: To find out whether COVID-19 may cause different manifestations and outcomes in the antepartum and postpartum period or not.
CLINICAL CHARACTERISTICS
2/22/21
Koeppen M, Rosenberger P, Magunia H | Clin Med Insights Circ Respir Pulm Med
Aim: To assess the prevalence of cardiovascular comorbidities and complications in ICU-admitted coronavirus disease 2019 (COVID-19) patients.
CLINICAL CHARACTERISTICS
2/22/21
Patel RH, Acharya A, Chand HS, et al. | AIDS Res Hum Retroviruses
Aim: To examine trends of clinical outcomes among patients co-infected with HIV and SARS-CoV-2.
CLINICAL CHARACTERISTICS
2/22/21
Rambo APS, Goncalves LF, Fonzales AI, et al. | Sao Paulo Med J
Aim: To present scientific evidence regarding the impact of COVID-19 spreaders.
INFECTION CONTROL
2/22/21
Puyat JH, Ahmad H, Kazanjian H | CMH Initiative
Aim: To investigate home-based activities that have protective and therapeutic effects against mental health symptoms during pandemics and to identify if there are activities that are effective for specific groups.
2/22/21
Hawkins RB, Mehaffey JH, Charles EJ, et al. | Transplantation
Aim: To review the evidence on lung transplantation for severe post-coronavirus disease 2019 respiratory failure, including patient selection, perioperative management, and expected outcomes.
CANDIDATE THERAPEUTICS
2/22/21
Hoste L, Van Paemel R, Haerynck F | Eur J Pediatr
Aim: To perform a systematic review of published cases of this novel multisystem inflammatory syndrome in children associated with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/22/21
Silva DFO, Cobucci RN, de Paula Soares-Rachetti V, et al. | Cien Saude Colet
Aim: To identify the prevalence of anxiety among health professionals during the COVID-19 pandemic.
MENTAL HEALTH
2/22/21
Ahmed S, Jafri L, Hoodbhoy Z, et al. | Indian J Crit Care Med
Aim: To review the published literature on the prognostic role of serum procalcitonin (PCT) in COVID-19 cases.
CLINICAL CHARACTERISTICS
2/22/21
De Sire, A, Andrenelli E, Negrini F, et al. | Eur J Phys Rehabil Med
Aim: To report data of a systematic search performed on papers published in July 2020.
UPDATED
CLINICAL CHARACTERISTICS
2/22/21
Gesesew HA, Koye DN, Fetene DM, et al. | BMJ Open
Aim: To provide a comprehensive evidence on risk factors for transmission, disease severity and COVID-19 related deaths in Africa.
CLINICAL CHARACTERISTICS
2/22/21
Roshanshad A, Kamalipour A, Ashraf MA, et al. | Iran J Microbiol
Aim: To investigate the latest clinical evidence on the efficacy and safety of treatment with Remdesivir in hospitalized patients with COVID-19.
CANDIDATE THERAPEUTICS
2/22/21
Rahimzadeh M, Naderi N | J Med Virol
Aim: To shed light on COVID-19 mediated immune malfunction and highlight possible clues for effective treatments of this disease.
CANDIDATE THERAPEUTICS
2/20/21
Zhang JJY, Lee KS, Ong CW, et al. | Influenza Other Respir Viruses
Aim: To evaluate the diagnostic performance of serological testing in COVID?19 by providing summary sensitivity and specificity estimates with time from symptom onset.
DIAGNOSTICS
2/20/21
Sagredo-Olivares K, Morales-Gomez C, Aitken-Saavedra J | Med Oral Patol Oral Cir Bucal
Aim: To evaluate saliva as a diagnostic technique for COVID-19.
UPDATED
DIAGNOSTICS
2/20/21
Permana H, Huang I, Purwiga A, et al. | Pharmacol Rep
Aim: To address the association between the use of statins and risk of mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/19/21
Zhong Z, Li H, Zhu J, et al. | Medicine
Aim: To summarize the clinical characteristics of patients with severe or critically ill coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/19/21
Irfan O, Muttalib F, Tang K, et al. | Arch Dis Child
Aim: To compare paediatric COVID-19 disease characteristics, management and outcomes according to World Bank country income level and disease severity.
UPDATED
CLINICAL CHARACTERISTICS
2/19/21
Taherifard E, Taherifard E, Movahed H, et al. | Hematology
Aim: To systematically review the hematologic autoimmune complications in these patients.
CLINICAL CHARACTERISTICS
2/19/21
Javed A | CNS Neurol Disord Drug Targets
Aim: To assess the associated neurological manifestations with SARS CoV-2 infection.
CLINICAL CHARACTERISTICS
2/19/21
Creta M, Sagnelli C, Celentano G, et al. | J Med Virol
Aim: To highlight currently available literature data on the involvement of the urinary and male genital systems in SARS-SoV-2 infection.
CLINICAL CHARACTERISTICS
2/19/21
Dotto L, de Azevedo Kinalski M, Machado PS, et al. | J Evid Based Med
Aim: To assess the characteristics of different designs of systematic reviews (SRs) registered in the International Prospective Register of Systematic Reviews (PROSPERO) about COVID-19.
2/19/21
Godini H, Hoseinzadeh E, Hossini H | Rev Environ Health
Aim: To review the evidence on water and wastewater as potential sources of SARS-CoV-2 transmission.
INFECTION CONTROL
2/18/21
Maleki M, Anvari E, Hopke PK, et al. | Environ Res
Aim: To assess the association of air pollution especially particulate matter pollution in the transmission and acceleration of the spread of SARS-CoV-2.
INFECTION CONTROL
2/18/21
Shi L, Xu J, Xiao W, et al. | Ann Allergy Asthma Immunol
Aim: To explore the prevalence of asthma in COVID-19 patients and the relationship between asthma and COVID-19 patients with poor outcomes would be of paramount importance.
CLINICAL CHARACTERISTICS
2/18/21
Xu C, Yi Z, Cai R, et al. | Autoimmun Rev
Aim: To summarize the published and preprint literature that described the clinical characteristics and outcomes of COVID-19 patients with rheumatic diseases, and to provide a higher level of evidence for better clinical decision making.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Henrina J, Putra ICS, Lawrensia S, et al. | Proj Pediatr Cardiol
Aim: To investigate cardiac manifestations, treatment characteristics, and outcomes of paediatric inflammatory multisystem syndrome (PIMS) temporally associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) (PIMS-TS).
CLINICAL CHARACTERISTICS
2/17/21
de Souza DB, Frondana FV, Silva FD | Res Biomed Engineering
Aim: To establish reference parameters of ventilatory therapy used in the various levels of severity of adult patients affected by COVID-19, to assist health professionals and hospital managers who will purchase this equipment.
CANDIDATE THERAPEUTICS
2/17/21
Roshdy A, Zaher S, Fayed H, et al. | Front Cardiovasc Med
Aim: To report the cardiac tissue autopsy findings in coronavirus disease 2019 (COVID-19) decedents.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Maslennikov R, Poluektova E, Ivashkin V, et al. | Infect Dis
Aim: To provide a detailed systematic review of diarrhoea in adults with COVID-19.
CLINICAL CHARACTERISTICS
2/17/21
Bonora BM, Avogaro A, Fadini GP | J Endocrinol Invest
Aim: To summarize the current state of the art on DPP4i treatment and COVID-19-related outcomes in patients with diabetes mellitus.
CANDIDATE THERAPEUTICS
2/17/21
Atmosudigdo I, Pranata R, Anthonius M, et al.  | J Clin Exp Hepatol
Aim: To evaluate whether dyslipidemia affects the mortality and severity of COVID-19, we also aimed to evaluate whether other comorbidities influence the association.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Rauschenberg C, Schick A, Hirjak D, et al. | J Med Internet Res
Aim: To investigate the theoretical and empirical base, user perspective, safety, effectiveness, and cost-effectiveness of digital interventions in public mental health provision (i.e. mental health promotion, prevention and treatment of mental disorders) that may help to reduce the consequences of the current COVID-19 pandemic.
MENTAL HEALTH
2/17/21
Manyati TK, Mutsau M | Health Technol
Aim: To explore the effectiveness of telehealth interventions for the diagnosis, contact tracing and care of the corona virus disease of 2019 in sub Saharan Africa.
INFECTION CONTROL
2/17/21
Sirois F, Owens J | Front Psychiatry
Aim: To examine the factors associated with psychological distress among HCW during an outbreak.
UPDATED
MENTAL HEALTH
2/17/21
Nakhlband A, Fakhari A, Azizi H | Naunyn Schmiedebergs Arch Pharmacol
Aim: To assess outcomes of IFN-beta treatment in COVID-19 patients.
CANDIDATE THERAPEUTICS
2/17/21
Desborough J, Dykgraaf SH, Phillips C, et al. | Fam Pract
Aim: To synthesize accounts of primary care lessons learnt from past epidemics and their relevance to COVID-19.
INFECTION CONTROL
2/17/21
Bansal V, Mahapure KS, Bhurwal A, et al. | Front Med
Aim: To provide a detailed overview of existing literature on Remdesivir in COVID-19 to evaluate the benefits and adverse events. 
CANDIDATE THERAPEUTICS
2/17/21
Gao Y, Chen Y, Liu M, et al. | Epidemiol Infect
Aim: To clarify the association between nervous system diseases and severity or mortality in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Mohamed MFH, A-Shokri S, Yousaf Z, et al. | Front Cardiovasc Med
Aim: To systematically review the literature and explore the pooled prevalence of VTE, PE, and DVT in critically ill COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/17/21
Winograd DM, Fresquez CL, Egli M, et al. | Patient Educ Couns
Aim: To review the evidence on the risk communication interventions to mitigate risk from viruses to determine if such interventions are efficacious.
INFECTION CONTROL
2/17/21
Kumar D, Severn M | CADTH
2/17/21
Kheyami ZA, Alharthi SS, Alanazi NS, et al. | Ann Med Health Sci Res
Aim: To determine the safety of systemic steroids and mortality rate in severe COVID-19 patients.
CANDIDATE THERAPEUTICS
2/17/21
Chaudhary R, Garg J, Houghton DE, et al. | Mayo Clin Proc Innov Qual Outcomes
Aim: To evaluate differences in thrombo-inflammatory biomarkers between patients with severe COVID-19 infection/death and mild infection.
CLINICAL CHARACTERISTICS
2/17/21
Jenner WJ, Kanji R, Mirsadraee S, et al. | J Thromb Thrombolysis
Aim: To identify the rate of thrombotic complications in ICU-treated patients with COVID-19, to inform recommendations for diagnosis and management.
CLINICAL CHARACTERISTICS
2/16/21
Umakanthan S, Chattu VK, Ranade AV, et al. | AIMS Public Health
Aim: To give a detailed insight into the recent trends of diagnosis and therapeutic options for COVID-19. 
CANDIDATE THERAPEUTICS
2/16/21
Labad J, Gonzalez-Rodriguez A, Cobo J, et al.  | PeerJ
Aim: To explore whether the coronavirus disease 2019 (COVID-19) pandemic is associated with toilet paper hoarding and to assess which risk factors are associated with the risk of toilet paper hoarding.
UPDATED
2/16/21
Sharifian-Dorche M, Sahraian MA, Fadda G, et al. | Mult Scler Relat Disord
Aim: To review the existing literature investigating the impact of disease-modifying therapies(DMT) on COVID-19 risks in this group of patients.
CANDIDATE THERAPEUTICS
2/16/21
Chang R, Elhusseiny KM, Yeh Y, et al. | PLoS One
Aim: To review the evidence on COVID-19 intensive care unit (ICU) patient characteristics, rates and risks of invasive mechanical ventilation (IMV) and associated outcomes.
UPDATED
CLINICAL CHARACTERISTICS
2/16/21
Sallam M | Vaccines
Aim: To assess the acceptance rates for COVID-19 vaccine(s) in different countries worldwide, which can provide an initial step to study the factors implicated in regional and cultural differences behind COVID-19 vaccine hesitancy.
INFECTION CONTROL
2/16/21
Ding H, He F, Lu YG, et al. | Eur Rev Med Pharmacol Sci
Aim: To evaluate the effects of non-drug interventions on anxiety, depression and sleep in patients with COVID-19 to provide guidance for clinical application.
MENTAL HEALTH
2/16/21
Wang J, Zhong Z, Mo Y, et al. | Eur Rev Med Pharmacol Sci
Aim: To determine the incidence of the clinical manifestations of COVID-19 in children.
UPDATED
CLINICAL CHARACTERISTICS
2/16/21
Fiest KM, Leigh JP, Krewulak KD, et al. | BMC Psychiatry
Aim: To review the evidence on the experiences and management of psychological symptoms in physicians during infectious disease outbreaks to better understand and support physician health during this unprecedented time.
MENTAL HEALTH
2/16/21
Ebina-Shibuya R, Namoong H, Horita N, et al. | J Thorac Dis
Aim: To evaluate HCQ/CQ treatment for COVID-19.
CANDIDATE THERAPEUTICS
2/16/21
Cavalcante-Leao BL, de Araujo C, Basso I, et al. | J Clin Exp Dent
Aim: To verify whether there is evidence in the literature regarding the decrease in viral load present in saliva after using three types of mouthwashes.
UPDATED
INFECTION CONTROL
2/16/21
Sarria-Guzman Y, Fusaro C, Bernal JE, et al. | J Infect Dev Ctries
Aim: To identify and to evaluate the reports associated on Knowledge, Attitude and Practices (KAP) towards COVID-19 pandemic in America.
2/16/21
Zhu F, Zozaya C, Zhou Q, et al. | Arch Dis Child Fetal Neonatal Ed
Aim: To systematically review and meta-analyse the available evidence for the presence of SARS-CoV-2 genome in the breastmilk of mothers who tested positive for COVID-19.
INFECTION CONTROL
2/16/21
Zinellu A, Mangoini AA | Front Med
Aim: To review the available evidence on the clinical implications of this protein specifically in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/16/21
Khan FA, Stewart I, Fabbri L, et al. | Thorax
Aim: To systematically review and assess the effectiveness of specific interleukin-1 and -6 inhibitors for the treatment of coronavirus-related infections. 
UPDATED
CANDIDATE THERAPEUTICS
2/16/21
Darbandi A, Asadi A, Ghanavati R, et al. | Int J Infect Dis
Aim: To evaluate the effects of probiotic on patient’s respiratory tract infection (RTI), a systematic review was conducted on randomized controlled trials (RCTs). 
CANDIDATE THERAPEUTICS
2/16/21
Bignardi PR, Vengrus CS, Aquino BM, et al. | Pathog Glob Health
Aim: To assess the association of hydroxychloroquine use with the virological cure, clinical recovery, mortality, and development of adverse effects in patients with COVID-19. 
CANDIDATE THERAPEUTICS
2/16/21
Sarfraz A, Sarfraz Z, Razzack AA, et al. | Clin Appl Thromb Hermost
Aim: To determine the risk of developing VTE after corticosteroid administration during COVID-19 treatment.
CANDIDATE THERAPEUTICS
2/15/21
Udeh R, Advani S, de Guadiana Romualdo LG, et al. | J Clin Med
Aim: To carefully evaluate the levels of calprotectin (serum, plasma or fecal) in severe and non-severe COVID-19, and also identify the implications of raised levels of calprotectin.
DIAGNOSTICS
2/15/21
Yazew BG, Abate HK, Mekonnen CK | Patient Prefer Adherence
Aim: To investigate the status of people’s knowledge, attitude, and practice about coronavirus disease preventive measures in Ethiopia in 2020.
INFECTION CONTROL
2/13/21
Chowdhury P, Paul SK, Kaisar S, et al. | Transp Rep E Logist Transp Rev
Aim: To  systematically review existing research on the COVID-19 pandemic in supply chain disciplines.
2/13/21
Zace D, Hoxhaj I, Orfino A, et al.  | J Psychiatr Res
Aim: To identify and summarize the implemented interventions to deal with mental health issues of HCWs during infectious disease outbreaks, and report their effectiveness.
UPDATED
MENTAL HEALTH
2/12/21
Singh B, Ryan H, Kredo T, et al. | Cochrane Database Syst Rev
Aim: To evaluate the effects of chloroquine or hydroxychloroquine for treatment people with COVID-19 and for preventing infection in people at risk of exposure or exposed to SARS-CoV-2.
UPDATED
CANDIDATE THERAPEUTICS
2/12/21
Ng WH, Tipih T, Makoah NA, et al. | mBio
Aim: To evaluate the correlation between comorbidities and their role in the exacerbation of disease in COVID-19 patients leading to fatal outcomes. 
CLINICAL CHARACTERISTICS
2/12/21
Nanda A, Hung I, Kwong A, et al. | J Evid Based Med
Aim: To evaluate the preclinical and clinical evidence on use of cloth and surgical face masks in SARS-CoV-2 transmission and proposes a trial to gather further evidence.
INFECTION CONTROL
2/11/21
Nasiri K, Dimitrova A | J Dent Sci
Aim: To evaluate saliva specimen in comparison to nasopharyngeal swab (NPS) specimen.
DIAGNOSTICS
2/11/21
Tur-Kaspa I, Tur-Kaspa T, Hildebrand G, et al. | F S Rev
Aim: To determine if COVID-19 is an STD or not, and to clarify its possible effect on fertility.
CLINICAL CHARACTERISTICS
2/11/21
Yan W, Chen D, Bigambo FM, et al. | BMC Infect Dis
Aim: To determine differences in blood cells, lymphocyte subsets, and cytokines in COVID-19 patients with different clinical stages.
CLINICAL CHARACTERISTICS
2/11/21
Vergara-Merino L, Meza N, Couve-Perez C, et al. | Acta Obstet Gynecol Scand
Aim: To conduct a comprehensive analysis of the current evidence on prognosis of COVID-19 in pregnant women.
CLINICAL CHARACTERISTICS
2/11/21
Bauer M, Groesdonk HV, Preissing F, et al. | Anaesthesist
Aim: To estimate 30-day and 90-day mortality of patients with sepsis and patients with septic shock in Germany and to compare the mortality with that of other industrialized regions (Europe, North America).
2/11/21
Jin Y, Trope GE, El-Defrawy S, et al. | Eur J Ophthalmol
Aim: To summarize COVID-19 research endeavors by ophthalmologists/researchers in terms of publication numbers, journals and author countries, and to detail key findings.
CLINICAL CHARACTERISTICS
2/11/21
Bavishi C, Whelton PK, Mancia G, et al. | J Hypertens
Aim: To evaluate the association of angiotensin-converting-enzyme inhibitors (ACEI) or AT1 blockers (ARB) therapy with clinical outcomes in patients with coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
2/11/21
Thompson H, Mousa A, Dighe A, et al.  | Clin Infect Dis
Aim: To estimate secondary attack rates (SAR) and observed reproduction numbers (Robs) in different settings exploring differences by age, symptom status, and duration of exposure.
UPDATED
INFECTION CONTROL
2/11/21
Alonso SG, Marques G, Barrachina I, et al. | Health Technol
Aim: To present a systematic review of the application of telemedicine and e-health systems to combat COVID-19. 
INFECTION CONTROL
2/10/21
Hariyanto TI, Rizki NA, Kurniawan A | Int Arch Otorhinolaryngol
Aim: To analyze the potential usefulness of anosmia or hyposmia in the detection of the COVID-19 infection.
DIAGNOSTICS
2/10/21
Syangtan G, Bista S, Dawadi P, et al. | Front Public Health
Aim: To review the evidence on the frequency of asymptomatic individuals and estimated occurrence by age group and gender.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Jayant K, Reccia I, Virdis F, et al. | Clin Transplant
Aim: To determine the pooled prevalence of outcomes among hospitalized LTx recipients with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Dhar SK, Vishnupriayn K, Damodar S, et al. | Heliyon
Aim: To establish association between induced cytokines and COVID-19 disease severity to help in prognosis and clinical care.
CLINICAL CHARACTERISTICS
2/10/21
 | NSW Health COVID-19 Critical Intelligence Unit
2/10/21
Marafini I, Troncone E, Rocchetti I, et al. | Front Pharmacol
Aim: To determine the risk of RTIs with vedolizumab in patients with IBD.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Kumar J, Meena J, Yadav A, et al.  | J Matern Fetal Neonatal Med
Aim: To synthesize the current evidence for the presence of SARS-CoV-2 RNA in the human milk of mothers with confirmed COVID-19 and its potential role in neonatal SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Umnuaypornlert A, Kanchanasurakit S, Lucero-Prisno DE, et al. | Tob Induc Dis
Aim: To determine the association between smoking and disease severity in COVID-19 infected patients.
UPDATED
CLINICAL CHARACTERISTICS
2/10/21
Dorantes-Acosta E, Ávila-Montiel D, Klünder-Klünder M, et al. | Front Oncol
Aim: To understand the survival and associated complications in pediatric cancer patients as well as their hospitalization, intensive care, and ventilation care (supplemental oxygen/endotracheal intubation) needs.
CLINICAL CHARACTERISTICS
2/10/21
Nassar M, Nso N, Baraka B, et al. | Diabetes Metab Syndr
Aim: To summarize the prevalence, clinical findings, and outcomes of COVID-19 in patients with T1DM, based on the findings of available evidence.
CLINICAL CHARACTERISTICS
2/9/21
Chedid M, Waked R, Haddad E, et al. | J Infect Public Health
Aim: To report available information in the literature regarding frequency, indications, types of antibiotic usage, duration, and their efficacy in Covid-19 patients.
CANDIDATE THERAPEUTICS
2/8/21
Sunjaya AP, Allida SM, Di Tanna GL, et al. | J Asthma
Aim: To summarise evidence on the risk of infection, severe illness and death from COVID-19 in people with asthma.
CLINICAL CHARACTERISTICS
2/8/21
Laurentius A, Mendel B, Prakoso R | Egypt Heart J
Aim: To show clinical outcome of renin-angiotensin-aldosterone system blockers in hospital treatment of hypertensive patients with coronavirus disease 2019
CLINICAL CHARACTERISTICS
2/8/21
Bhatta M, Nandi S, Dutta S, et al. | Hum Vaccin Immunother
Aim: To analyze the availability, development and status of new COVID-19 vaccine candidates as well as the status of vaccines for other diseases that might be effective against SARS-CoV-2 infection.
CANDIDATE THERAPEUTICS
2/8/21
Li P, Li L, Wang S, et al. | Cancer Med
Aim: To systematically review the present evidence on the relationship between antitumor therapy and the clinical outcomes of COVID?19 and to analyze and summarize the available studies in this meta?analysis.
CLINICAL CHARACTERISTICS
2/8/21
Vegivinti CTR, Pederson JM, Saravu K, et al. | J Clin Apher
Aim: To examine clinical outcomes associated with convalescent plasma therapy in COVID-19 patients.
CANDIDATE THERAPEUTICS
2/8/21
Dabone C, Mbagwu I, Muray M, et al. | J Racial Ethn Health Disparities
Aim: To assess the food insecurity conditions of ACB populations globally during the COVID-19 pandemic.
2/8/21
Servante J, Swallow G, Thornton JG, et al. | BMC Pregnancy Childbirth
Aim: To determine the rate of arterial or venous thrombosis in pregnant women with confirmed or suspected COVID-19 and to estimate the rate of acquired coagulopathy in pregnant women with confirmed or suspected COVID-19.
CLINICAL CHARACTERISTICS
2/8/21
Mir T, Sattar Y, Ahmad J, et al. | Catheter Cardiovasc Interv
Aim: To meta?analyze studies that examined in?hospital cardiac arrest in COVID patients.
CLINICAL CHARACTERISTICS
2/8/21
Kim DH, Kim SW, Stybayeva G, et al. | Clin Exp Otorhinolaryngol
Aim: To evaluate the diagnostic value of the various symptoms of COVID-19 in the screening of this disease.
DIAGNOSTICS
2/8/21
Yuan K, Gong Y, Liu L, et al. | Mol Psychiatry
Aim: To provide a reliable estimate of the worldwide prevalence of PTSD after large-scale pandemics as well as associated risk factors.
MENTAL HEALTH
2/8/21
 | NSW Health COVID-19 Critical Intelligence Unit
2/8/21
Pal R, Banerjee M, Yadav U, et al. | Postgrad Med J
Aim: To provide an updated summary and collate the effect of statin use on clinical outcomes in COVID-19 using unadjusted and adjusted risk estimates.
CANDIDATE THERAPEUTICS
2/5/21
Pasin L, Cavalli G, Navalesi P, et al. | Eur J Intern Med
Aim: To investigate the effect of anakinra in COVID-19 on survival and need for mechanical ventilation.
CANDIDATE THERAPEUTICS
2/5/21
Beyrouti R, Best JG, Chandratheva A, et al. | J Neurol
Aim: To describe the characteristics of spontaneous symptomatic intracerebral haemorrhage (ICH) associated with COVID-19.
CLINICAL CHARACTERISTICS
2/5/21
Xu Z, Tang Y, Huang Q, et al. | BMC Nephrol
Aim: To evaluate the incidence of AKI in hospitalized COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
2/4/21
Belsky JA, Tullius BP, Lamb MG, et al. | J Infect
Aim: To define clinical features, laboratory testing, therapeutic interventions and outcomes in immunocompromised patients and then compared these results to the general population with COVID-19.
CLINICAL CHARACTERISTICS
2/4/21
Anderson G, Casasanta D, Cocchieri A, et al. | J Clin Nurs
Aim: To identify the main diagnostic features of SARS-CoV-2 positive patients at the time of hospitalization and their prevalence.
DIAGNOSTICS
2/4/21
Aghalari Z, Dahms H, Sosa-Hernandez JE, et al. | Environ Res
Aim: To evaluate SARS-COV-2 transmission through indoor air in hospitals and its prevention methods.
INFECTION CONTROL
2/4/21
Jain V, Kanchan T, Krishan K | Acta Biomed
Aim: To review the evidence on the vertical transmission of SARS-CoV-2.
INFECTION CONTROL
2/4/21
Elshazli RM, Kline A, Elgaml A, et al. | J Med Virol
Aim: To identify COVID-19 patients presenting with gastrointestinal (GI) symptoms during the first and second pandemic waves and investigate their association with the disease outcomes.
CLINICAL CHARACTERISTICS
2/4/21
Li G, Yang Y, Gao D, et al. | Int J Med Sci
Aim: To comprehensively explore the prevalence of transaminase elevation and liver injury in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/4/21
Alamer AA, Almulhim AS, Alrashed AA, et al. | Healthcare
Aim: To estimate the pooled risks of mortality and disease severity associated with ACEI/ARB use during the first wave of the pandemic.
CLINICAL CHARACTERISTICS
2/4/21
Rezagholizadeh A, Khiali S, Sarbakhsh P, et al. | Eur J Pharmcol
Aim: To evaluate the efficacy and safety of remdesivir administration in COVID-19 patients. 
CANDIDATE THERAPEUTICS
2/3/21
 | CMH Initiative
2/3/21
Naeini MB, Sahebi M, Nikbakht F, et al. | Obes Med
Aim: To quantify meta-analytic findings on the association of cardiovascular disease (CVD) comorbidities and COVID-19 severity.
CLINICAL CHARACTERISTICS
2/3/21
Hatmi ZN | SN Compr Clin Med
Aim: To conduct a systematic review of published systematic reviews to provide comprehensive updated information on COVID-19.
CLINICAL CHARACTERISTICS
2/3/21
He X, Cheng X, Feng X, et al. | Front Public Health
Aim: To review the clinical symptoms of the COVID-19 epidemic systematically.
CLINICAL CHARACTERISTICS
2/3/21
Hasnain M, Pasha MF, Ghani I | J Biosaf Biosecur
Aim: To review the evidence on the combined measures taken to control the transmission of COVID-19 in Wuhan.
INFECTION CONTROL
2/3/21
Li J, Liao X, Zhou Y, et al. | Shock
Aim: To review the evidence on the response to glucocorticioids treatment in COVID-19 and SARS patients.
UPDATED
CANDIDATE THERAPEUTICS
2/3/21
Castaneda CA, Castillo M, Rojas JL, et al. | Rev Peru Med Exp Salud Publica
Aim: To describe the risk of infection and developing severe COVID-19 in cancer patients.
UPDATED
CLINICAL CHARACTERISTICS
2/3/21
Lopez-Valenciano A, Suarez-Iglesias D, Sanchez-Lastra MA, et al. | Front Psychol
Aim: To analyze the impact that the COVID-19 lockdown had on the amount of physical activity performed by university students.
2/3/21
Scooppettuolo P, Borrelli S, Naeije G | Brain Behav Immun Health
Aim: To provide a clinical approach of SARS-CoV-2 neurological complications based on the direct or indirect (systemic/immune-mediated) role of the SARS-CoV-2 in their genesis.
CLINICAL CHARACTERISTICS
2/3/21
Nasiri N, Sharifi H, Bazrafshan A, et al. | J Ophthalmic Vis Res
Aim: To investigate the prevalence of ocular manifestations in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/3/21
Pourmalek F, Hemami MR, Janani L, et al. | BMC Public Health
Aim: To inform the researchers about the methodology and results of epidemic estimation studies performed for COVID-19 epidemic in Iran, we aimed to perform a rapid review.
UPDATED
2/3/21
Cevik M, Tate M, Lloyd O, et al. | Lancet Microbe
Aim: To characterise the viral load dynamics of SARS-CoV-2, duration of viral RNA shedding by RT-PCR, and viable virus shedding in various body fluids, and to compare SARS-CoV-2 viral dynamics with those of SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV).
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Xiang G, Li X, Chen Z, et al. | Ann Palliat Med
Aim: To systematically review the clinical risk factors for fatal outcome of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Li H, Zhao Y, Zhou L, et al. | Dermatol Ther
Aim: To present heterogeneous cutaneous, histopathological manifestations in COVID?19 patients, to investigate the possible relationship between cutaneous manifestations and histopathological features in COVID?19 infection.
CLINICAL CHARACTERISTICS
2/1/21
Pijls BG, Jolani S, Atherley A, et al. | BMJ Open
Aim: To describe the associations of age and sex with the risk of COVID-19 in different severity stages ranging from infection to death.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
AlJohani AMA, Tharwat TJA, Mahrous KW, et al. | World Fam Med J
Aim: To outline and identify a wide range of diagnostic and therapeutic options for COVID-19.
CANDIDATE THERAPEUTICS
2/1/21
Ghimire S, Sharma S, Patel A, et al. | SN Compr Clin Med
Aim: To provide a more comprehensive and generalizable understanding of the GI manifestations, and its association with severity in COVID-19 patients.
CLINICAL CHARACTERISTICS
2/1/21
Yisak H, Ewunetei A, Kefale B, et al. | Risk Manag Healthc Policy
Aim: To summarize and decide if there were a link between vitamin D status and COVID-19 infection and prognosis.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Sood M, Sharma S, Sood I, et al. | SN Compr Clin Med
Aim: To analyse the clinical features, proposed pathogenesis and current treatment options for effective management of children with this novel entity.
CLINICAL CHARACTERISTICS
2/1/21
Diaz LA, Idalsoaga F, Cannistra M, et al. | World J Gastroenterol
Aim: To characterize hepatic pathological findings in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Wibowo A, Pranata R, Astuti A, et al. | J Intensive Care
Aim: To assess whether ventricular longitudinal strain can be used as a prognostication tool in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Lee RA, Herigon JC, Benedetti A, et al. | J Clin Microbiol
Aim: To understand the performance of alternative sample types compared to NP swabs
UPDATED
DIAGNOSTICS
2/1/21
Yoon SH, Yang S, Cho H, et al.  | Eur Rev Med Pharmacol Sci
Aim: To evaluate the diagnostic accuracy of the Food and Drug Administration Emergency Use Authorization (FDA-EUA) authorized point-of-care tests (POCTs) for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
UPDATED
DIAGNOSTICS
2/1/21
d'Ettore G, Ceccarelli G, Santinelli L, et al. | Int J Environ Res Public Health
Aim: To analyze the literature to discover which topics have been focused on and what the latest developments are in managing the occupational risk of PTSS in HCWs during the current pandemic.
MENTAL HEALTH
2/1/21
Santabarbara J, Bueno-Notivol J, Lipinicki DM, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To review the evidence on the prevalence of anxiety in health care professionals during the COVID-19 pandemic.
MENTAL HEALTH
2/1/21
Yang J, Zheng Y, Gou X, et al. | Int J Infect Dis
Aim: To assess the prevalence of comorbidities in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients and the risk of underlying diseases in severe patients compared to non-severe patients.
CLINICAL CHARACTERISTICS
2/1/21
Merola E, Armelao F, de Pretis G | Acta Gastroenterol Belg
Aim: To assess the frequency of gastrointestinal (GI) involvement in COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Martha JW, Wibowo A, Pranata R | Postgrad Med J
Aim: To evaluate the prognostic performance of elevated lactate dehydrogenase (LDH) in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Gronholm P, Nose M, van Brakel WH, et al. | Epidemiol Psychiatr Sci
Aim: To develop recommendations for strategies and interventions to reduce stigma and discrimination related to COVID-19.
UPDATED
MENTAL HEALTH
2/1/21
Agostini F, Mangone M, Ruiu P, et al. | J Rehabil Med
Aim: To identify the best evidence to define rehabilitative approaches to acute and post-acute phases of coronavirus 2019 (COVID-19) disease.
CANDIDATE THERAPEUTICS
2/1/21
Al-abdouh A, Bizanti A, Barbarawi M, et al. | Contemp Clin Trials
Aim: To evaluate the effect of remdesivir in the treatment of moderate and severe COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
2/1/21
Lee HW, Yoon C, Jang EJ, et al. | Thorax
Aim: To investigate if ACEI/ARB use is associated with the risk of mortality and severe disease in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/1/21
Zhang T, Huang W, Guan W, et al. | J Thorac Dis
Aim: To review the evidence on the clinical characteristics between severe and non-severe pateints in the outbreak of COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Uaprasert N, Moonla C, Sosothikul D, et al. | Clin Appl Thromb Hermost
Aim: To estimate the burden of systemic coagulation activation in patients with COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Chen C, Zhu C, Yan D, et al. | Int J Infect Dis
Aim: To summarize the epidemiological and radiographical characteristics of asymptomatic infections with COVID-19.
CLINICAL CHARACTERISTICS
2/1/21
Prati G, Mancini AD | Psychol Med
Aim: To determine the psychological impact of COVID-19 lockdowns on the general population.
MENTAL HEALTH
2/1/21
Bastos ML, Perlman-Arrow S, Menzies D, et al. | Ann Intern Med
Aim: To determine the difference in sensitivity for SARS-CoV-2 detection between nasopharyngeal swabs and saliva and estimate the incremental cost per additional SARS-CoV-2 infection detected with nasopharyngeal swabs.
UPDATED
DIAGNOSTICS
2/1/21
Han YJ, Lee KW, Yoon S, et al. | Theranostics
Aim: To highlight therapeutic agents that might be effective in treating COVID-19.
CANDIDATE THERAPEUTICS
1/30/21
Robaina-Castellanos GR, de la Caridad Riesgo-Rodriguez S | MEDICC Rev
Aim: To summarize and analyze the published evidence on forms of SARS-CoV-2 vertical transmission (either intrauterine or intrapartum).
INFECTION CONTROL
1/29/21
Khatami F, Saatchi M, Zadeh SST, et al. | Sci Rep
Aim: To determine the diagnostic value of an initial chest CT scan in patients with COVID-19 infection in comparison with RT-PCR. 
DIAGNOSTICS
1/29/21
Yu YJ, Park YS, Keller A, et al. | Int J Environ Res Public Health
Aim: To synthesize existing findings (both qualitative and quantitative) that focus on the social and cultural impacts of coronaviruses in order to gain a better understanding of the COVID-19 pandemic.
1/29/21
Lawes-Wickwar S, Ghio D, Tang MY, et al. | Vaccines
Aim: To identify and synthesise evidence relating to effective messaging for encouraging vaccination in order to prevent virus transmission during pandemics or epidemics.
UPDATED
INFECTION CONTROL
1/29/21
Peravali M, Joshi I, Ahn J, et al. | JTO Clin Res Rep
Aim: To outline patient characteristics, challenges in diagnosis and treatment, and outcomes of lung cancer patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Goel H, Gupta I, Mourya M, et al. | Obstet Gynecol Sci
Aim: To review the evidence on the clinical and laboratory parameters of COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Kinobe RT, Owens L | Fundam Clin Pharmacol
Aim: To present an integrative, critical appraisal of the qualitative and quantitative antiviral properties of ivermectin for putative applications in agriculture and medicine with examination of SARS?CoV?2.
CANDIDATE THERAPEUTICS
1/29/21
Tleyjeh IM, Bin Abdulhak AA, Tlayjeh H, et al. | Am J Ther
Aim: To perform a meta-analysis of the association between prior use of ACEIs and ARBs and the risk of SARS-CoV-2 infection or hospitalization due to COVID-19 disease.
CLINICAL CHARACTERISTICS
1/29/21
Langford BJ, So M, Raybardhan S, et al. | Clin Microbiol Infect
Aim: To estimate the prevalence and associated factors of antibiotic prescribing in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Arias FA, Chavez PT, Panato AM, et al. | J of Pharmaceutical Res
Aim: To conduct a systematic review of the possible antivirals studied that could be useful in this public health catastrophe.
CANDIDATE THERAPEUTICS
1/29/21
Lee JJ, Montazerin SM, Jamil A, et al. | J Med Virol
Aim: To review and synthesize the current evidence on the association of RDW levels with COVID?19 mortality and severity.
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Mendes NF, Jara CP, Mansour E, et al. | Allergy Asthma Clin Immunol
Aim: To conduct a systematic review of the diagnosis of asthma as a premorbid condition in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Silverio A, Di Maio M, Citro R, et al. | BMC Cardiovasc Disord
Aim: To investigate the relationship between cardiovascular risk factors and in-hospital mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Baldini T, Asioli GM, Romoli M, et al. | Eur J Neurol
Aim: To systematically review the available evidence in the literature for cerebral venous thrombosis (CVT) in association with coronavirus disease-2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Chen M, Qin R, Mei J, et al. | Int J Infect Dis
Aim: To investigate the diagnostic effectiveness of SARS-CoV-2 specific antibodies stratified by different positive results.
DIAGNOSTICS
1/29/21
Jafari M, Pormohammad A, Sheikh Neshin SA, et al. | Rev Med Virol
Aim: To provide comprehensive data regarding pregnant patients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
1/29/21
Huang C, Soleimani J, Herasevich S, et al. | Mayo Clin Proc
Aim: To synthesize the current and emerging literature describing the clinical features, treatment, outcomes, and risk factors associated with poor prognosis among critically ill patients with COVID-19 during the early months of the pandemic. To provide frontline clinicians with insights for the effective management of severely ill patients with COVID-19. To identify knowledge gaps to guide future research endeavors.
CLINICAL CHARACTERISTICS
1/29/21
Singh AK, Jena A, Kumar-M P, et al. | Intest Res
Aim: To review the evidence on the various clinical manifestations of SARS-CoV-2 in patients with IBD, and to estimate the pooled prevalence of different clinical manifestations.
CLINICAL CHARACTERISTICS
1/29/21
Barycka K, Szarpak L, Filipiak KJ, et al. | PLoS One
Aim: To review the relevant and available published RCTs with the aid of the increased power of meta-analytic methods in order to assess the effectiveness of medical masks and N95 respirators in reducing the risk of respiratory infections.
INFECTION CONTROL
1/29/21
Butler-Laporte G, Lawandi A, Schiller I, et al. | JAMA Intern Med
Aim: To assess the diagnostic accuracy of saliva NAAT for COVID-19.
DIAGNOSTICS
1/29/21
Gross JV, Mohren J, Erren TC | BMJ Open
Aim: To review the evidence on health risks at the workplace and the effectiveness of enacted preventative measures for COVID-19.
INFECTION CONTROL
1/29/21
Gholami M, Fawad I, Shadan S, et al. | Int J Infect Dis
Aim: To describe the clinical outcomes and risk factors for SARS- CoV-2 infection in HCW.
CLINICAL CHARACTERISTICS
1/29/21
Xiang Y, Jia Y, Chen L, et al. | Infect Dis Model
Aim: To review the evidence on epidemic prediction models of COVID-19 and the public health intervention strategies.
INFECTION CONTROL
1/29/21
Raynaud M, Zhang H, Louis K, et al. | BMC Med Res Methodol
Aim: To review and categorize COVID-19-related medical research and to critically appraise peer-reviewed original articles.
1/29/21
Yasuhara J, Watanabe K, Takagi H, et al. | Pediatr Pulmonol
Aim: To investigate the epidemiology and clinical course of MIS-C.
CLINICAL CHARACTERISTICS
1/29/21
Rodriguez-Guerra M, Jadhav P, Vittorio TJ | Drugs Context
Aim: To assess the efficacy and safety of these available therapies in light of current evidence. 
CANDIDATE THERAPEUTICS
1/29/21
Anglemyer A, Moore TH, Parker L, et al. | Cochrane Database Syst Rev
Aim: To assess the benefits, harms, and acceptability of personal digital contact tracing solutions for identifying contacts of an identified positive case of an infectious disease.
UPDATED
INFECTION CONTROL
1/29/21
Vargo D, Zhu L, Benwell B, et al. | Human Behaviour and Emerging Technologies
Aim: To synthesize the rapidly growing literature on digital technology use during the current COVID?19 pandemic. To address the following four topics: (1) the specific digital technologies that have been used, (2) the specific populations who have used these digital technologies, (3) the specific activities that individuals and groups have used these digital technologies, and (4) the specific effects of using these digital technologies on humans during the pandemic.
1/29/21
Parsons JE, Newby KV, French DP | Br J Health Psychol
Aim: To examine interventions reported in the literature to see whether those that include risk messages have been successful in influencing risk appraisals and the subsequent intentions and uptake of vaccination.
INFECTION CONTROL
1/29/21
Parkinson N, Rodgers N, Head Fourman M, et al. | Sci Rep
Aim: To systematically identify and combine existing data from human betacoronavirus research to generate a comprehensive ranked list of host genes involved in COVID-19.
CLINICAL CHARACTERISTICS
1/29/21
Xue Y, Sun S, Cai J, et al. | J Renin Angiotensin Aldosterone Syst
Aim: To conduct a meta-analysis on the effects of ACEI/ARB on disease symptoms and laboratory tests in hypertensive patients infected with COVID-19 virus and those who did not use ACEI/ARB.
CLINICAL CHARACTERISTICS
1/29/21
Cao C, Wang J, Li Y, et al. | Int J Clin Pract
Aim: To evaluate the relationship between OM-85 consumption and recurrent respiratory tract infections.
CANDIDATE THERAPEUTICS
1/29/21
Horn M, Ratansi A, Varia M | Region of Peel - Public Health
Aim: To answer the question: what population-level interventions will result in health behaviour change among travellers?
INFECTION CONTROL
1/29/21
Lim MA, Mulyadi Ridia KG, Pranata R | J Clin Orthop Trauma
Aim: To evaluate the 30-day mortality, number and site of fracture, mechanism of injury, and location where injury was sustained during the pandemic compared to pre-pandemic.
1/29/21
Yao MQ, Zheng QX, Xu J, et al. | Journal of Zhejiang University-SCIENCE B
Aim: To summarize data on demographic characteristics, clinical features, and laboratory findings in non-recurrence and recurrence groups as well as to explore critical factors associated with COVID-19 recurrence.
CLINICAL CHARACTERISTICS
1/29/21
Wang Y, Kala MP, Jafar TH | PLoS One
Aim: To evaluate factors associated with psychological distress among the predominantly general population during the COVID-19 pandemic.
MENTAL HEALTH
1/29/21
Zhang Y, Yao F, Kuang X, et al. | Cancer Manag Res
Aim: To evaluate the quality of systematic reviews/meta-analyses (SR/MAs) on alternative exercise traditions in cancer care.
MENTAL HEALTH
1/29/21
Barek MA, Aziz MA, Islam MS | Heliyon
Aim: To evaluate the impact of age, sex, comorbidities, and clinical characteristics on the severity of COVID-19 to help diagnose and evaluate the current outbreak in clinical decision-making.
CLINICAL CHARACTERISTICS
1/29/21
Kitano T, Kitano M, Krueger C, et al. | PLoS One
Aim: To better understand the global epidemiology of COVID-19 in children and differences in outcome across countries.
UPDATED
CLINICAL CHARACTERISTICS
1/29/21
Lassi Z, Naseem R, Salam RA, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the impact of the COVID-19 pandemic on immunization campaigns and programs.
UPDATED
INFECTION CONTROL
1/28/21
Yang J, Ma Z, Lei Y | Epidemiol Infect
Aim: To re-evaluate the relationship between obesity and coronavirus-2019 (COVID-19).
CLINICAL CHARACTERISTICS
1/28/21
Mair MDD, Hussain M, Siddiqui S, et al | Br J Radiol
Aim: To perform a systematic review and meta-analysis to compare the diagnostic accuracy of Computed tomography (CT) and initial Reverse transcriptase polymerase chain reaction (RT-PCR) for detecting COVID-19 infection.
DIAGNOSTICS
1/28/21
Sadaf A, Richards JL, Glanz J, et al | Vaccine
Aim: To amass and evaluate the literature on interventions to decrease parental vaccine refusal and hesitancy toward recommended childhood and adolescent vaccines.
INFECTION CONTROL
1/28/21
Piri SM, Edalatfar M, Shool S, et al. | Infect Dis
Aim: To evaluate rate of SARS-CoV-2 recurrence, changes in disease severity, the interval between negative RT-PCR test for SARS-CoV-2 and disease recurrence, disease and patients’ characteristics, risk factors for predicting recurrence and outcomes, as well as the prognosis of recurrent patients.
CLINICAL CHARACTERISTICS
1/28/21
Bhattacharjee S, Banerjee M, Pal R | Postgraduate Medical J
Aim: To summarise the available literature and provide a pooled analysis of the effect of A/AB (without anti-A antibodies) on clinical outcomes in COVID-19 patients compared with B/O (with anti-A antibodies) blood groups.
CLINICAL CHARACTERISTICS
1/28/21
Tabatabaeizadeh SA | Eur J Med Res
Aim: To investigate the airborne transmission of COVID-19 and the role of face mask to prevent it.
INFECTION CONTROL
1/28/21
Paliogiannis P, Mangoni AA, Cangemi M, et al. | Clin Exp Med
Aim: To investigate the associations between serum albumin concentrations and COVID-19 disease severity and adverse outcomes.
CLINICAL CHARACTERISTICS
1/27/21
Hussein MH, Elshazli RM, Attia AS, et al. | J Asthma
Aim: To compare asthmatic and non-asthmatic patients to determine the clinical significance of pre-existing asthma in COVID-19 patients. 
CLINICAL CHARACTERISTICS
1/27/21
Sharifi M, Asadi-Pooya AA, Mousavi-Roknabadi RS | Arch Acad Emerg Med
Aim: To systematically review the epidemiology of burnout and the strategies and recommendations to prevent or reduce it among healthcare providers (HCPs) of COVID-19 wards.
MENTAL HEALTH
1/27/21
Xie J, Wang Q, Xu Y, et al. | Ann Palliat Med
Aim: To summarize the characteristics of COVID-19 patients in the early stage of the pandemic and explore the risk factors of disease progression.
CLINICAL CHARACTERISTICS
1/27/21
Hoogenes B, Queree M, Townson A, et al.  | J Neurotrauma
Aim: To provide an overview of the clinical presentation, course, and outcomes of COVID-19 in persons with SCI and identify risk factors for severe disease- and COVID-19-related mortality.
UPDATED
CLINICAL CHARACTERISTICS
1/27/21
Hariyanto TI, Putri C, Frinka P, et al. | AIDS Res Hum Retroviruses
Aim: To analyze the relationship between HIV and poor outcomes of COVID-19 infection.
CLINICAL CHARACTERISTICS
1/27/21
Illahi U, Mir MS | Environ Dev Sustain
Aim: To identify and enhance the understanding of the logistical characteristics that play a vital role during pandemics. 
1/27/21
Rahman M, Ahmed R, Moitra M, et al. | Front Psychiatry
Aim: To collate evidence on human rights abuses and violations and resultant mental and behavioral health outcomes of different populations, especially those known to be at high risk or have greater vulnerabilities warranting additional mitigation, prevention, and treatment approaches during COVID-19.
MENTAL HEALTH
1/27/21
Vegivinti CTR, Pederson JM, Saravu K, et al. | Ann Med Surg
Aim: To perform a systematic review and meta-analysis of randomized controlled trials that examined remdesivir treatment for COVID-19.
CANDIDATE THERAPEUTICS
1/27/21
Tian C, Lovrics O, Vaisman A, et al. | Infect Control Hosp Epidemiol
Aim: To investigate risk factors for HCW infection in viral respiratory pandemics (SARS-CoV-2, MERS, SARS CoV-1, influenza A H1N1, influenza H5N1) and improve understanding of HCW risk management amidst the COVID-19 pandemic.
UPDATED
INFECTION CONTROL
1/26/21
Kumar S, Sarma P, Kaur H, et al. | Tissue Cell
Aim: To review the evidence on the utility of different cell culture systems as potential in-vitro models for repurposing and drugs development, vaccine development, isolation and pathogenesis of SARS-COV-2.
CANDIDATE THERAPEUTICS
1/26/21
Hartmann J, Ergang A, Mason D, et al. | Diagnostics
Aim: To review the evidence on thromboelastography for management of patients with COVID-19.
CLINICAL CHARACTERISTICS
1/25/21
Robertson-More C, Wu T | Surg Endosc
Aim: To better outline what is known regarding the risk of viral transmission in surgical smoke.
INFECTION CONTROL
1/25/21
Chtioui MJ, Harzallah N, Jebali MCO, et al. | Tunis Med
Aim: To synthesize the evidence on the efficacy and safety of using disinfection booths during the COVID-19 pandemic.
INFECTION CONTROL
1/25/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy, safety and rollout of COVID-19 vaccines.
1/25/21
Shrotri M, van Schalkwyk MCI, Post N, et al. | PLoS One
Aim: To summarize current understanding of the cellular response to SARSCoV-2 infection, specifically exploring the role that T cell-mediated immunity might play in resistance to severe infection, clinical and virological recovery, and long-term protection.
UPDATED
INFECTION CONTROL
1/25/21
Thapa BB, Shrestha D, Bista S, et al. | Surg J
Aim: To explore the consensus in modified standard urology care, that can be adopted and applied during COVID-19 and similar pandemic.
INFECTION CONTROL
1/22/21
Parry M, Bjornnes AK, Nickerson N, et al. | IRSC CIHR
Aim: To determine what is known about the mental health and wellbeing of family caregivers during communicable disease outbreaks.
1/22/21
Rakedzon S, Neuberger A, Domb AJ, et al. | J Travel Med
Aim: To review data on the potential of repurposing antiparasitic drugs against viruses in general, with an emphasis on coronaviruses.
CANDIDATE THERAPEUTICS
1/22/21
Shams S, Rathore SS, Anvekar P, et al. | Dermatol Ther
Aim: To summarize clinical features, histopathological hallmarks, and possible pathology behind the maculopapular skin eruptions occurring in Covid-19 patients.
CLINICAL CHARACTERISTICS
1/22/21
Pajo AT, Espiritu AI, Apor ADAO, et al. | Neurol Sci
Aim: To review the currently available neuropathological data on COVID-19 including post-mortem findings of patients following a death from COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
1/22/21
Onorato D, Pucci M, Carpene G, et al. | Semin Thromb Hemost
Aim: To provide an updated overview on the interplay between statins and COVID-19, with particular focus on their potentially protective role against progression toward severe or critical illness and death.
CANDIDATE THERAPEUTICS
1/22/21
Lim AYH, GOH JL, Chua MCW, et al. | BMC Pulm Med
Aim: To assess the temporal progression of blood and radiology findings of patients with COVID-19.
CLINICAL CHARACTERISTICS
1/22/21
Oran DP, Topol EJ | Ann Intern Med
Aim: To estimate the proportion of persons infected with SARS-CoV-2 who never develop symptoms.
CLINICAL CHARACTERISTICS
1/21/21
Baradaran A, Malek A, Moazzen N, et al. | Iran J Allergy Asthma Immunol
Aim: To describe clinical manifestation and outcomes of MIS-C associated with COVID-19.
1/21/21
Ho JSY, Fernando DI, Chan MY, et al. | Ann Acad Med Singap
Aim: To investigate the relationship between COVID-19 and obesity.
1/21/21
Zare ME, Wang Y, Kansestani AN, et al. | Iran J Allergy Asthma Immunol
Aim: To determine the accuracies of white blood cell counts and inflammatory biomarkers for prognosis of COVID-19 patient's outcome by a DTA meta-analysis.
1/20/21
Zolopa C, Hoj S, Bruneau J, et al. | Int J Drug Policy
Aim: To review the impacts of Big Events with relevance to the COVID-19 pandemic on drug-related risk and harms and access to drug treatment and harm reduction services.
1/20/21
Fernando I, Perera J, Udawaththa I, et al. | SSRN
Aim: To systemize and organize the contemporary knowledge on stockpiling behavior during a Pandemic. 
MENTAL HEALTH
1/20/21
Mameli S, Marcialis MA, Bassareo PP, et al. | Panmiverva Medica
Aim: To review the evidence on the features of liver involvement and damage in the course of COVID-19.
CLINICAL CHARACTERISTICS
1/19/21
Kheirabadi D, Haddad F, Mousavi-Roknabadi RS, et al. | J Med Virol
Aim: To clarify which systematic reviews on COVID?19 treatment are based on high?value evidence.
1/19/21
von Philipsborn P, Biallas R, Burns J, et al. | BMJ Open
Aim: To assess the effects of prior and current use of NSAIDs in patients with acute viral respiratory infections on acute severe adverse events , on acute healthcare utilization, as well as on quality of life and long-term survival.
WHO COLLABORATIVE
1/19/21
Meng J, Ma Y, Jia J, et al. | Front Immunol
Aim: To compare the similarities and differences focusing on ferritin and cytokine levels between severe COVID-19 and active AOSD. 
CLINICAL CHARACTERISTICS
1/19/21
Duz ME, Balci A, Menekse E | Tuberk Toraks
Aim: To review the evidence on D-dimer levels and mordidity and mortality in COVID-19 patients.
1/19/21
Kim J, Han SC, Jo HD, et al. | J Korean Med Sci
Aim: To investigate the factors that contribute to the inter-study variability in the prevalence of olfactory and gustatory dysfunction.
CLINICAL CHARACTERISTICS
1/19/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the infectivity, virulence, and effectiveness of the current vaccines against the new SARS-CoV-2 variants.
1/19/21
Sahebi A, Nejati-Zarnaqi B, Moayedi S, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To review the evidence on the prevalence of anxiety and depression among healthcare workers during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
1/19/21
Cunarro-Lopez Y, Pintado-Recarte P, Cueto-Hernandez I, et al. | J Clin Med
Aim: To describe and analyze the profile of the obstetric patients according to the country of origin of the publication.
UPDATED
CLINICAL CHARACTERISTICS
1/19/21
Cavicchioli M, Ferrucci R, Guidetti M, et al. | Healthcare
Aim: To provide an evidence-based assessment of possible effects of the current COVID-19 quarantine on mental health.
MENTAL HEALTH
1/18/21
McClatchey K, Jackson T, Delaney B, et al. | J Allergy Clin Immunol Pract
Aim: To explore whether the information addresses relevant health actions to minimize the risk of contracting and spreading COVID-19, and encourages asthma self-management.
CLINICAL CHARACTERISTICS
1/18/21
Zeng W, Qi K, Ye M, et al. | Eur J Gastroenterol Hepatol
Aim: To explore the relationship between gastrointestinal symptoms and the severity of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/18/21
Martha JW, Wibowo A, Pranata R | Diabetes Metab Syndr
Aim: To evaluate the prognostic performance of hypocalcemia in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
1/18/21
Kow CS, Hasan SS | J Asthma
Aim: To review the evidence on the overall effect of the chronic use of inhaled corticosteroids on the clinical outcomes in patients with coronavirus disease 2019 (COVID-19). 
CANDIDATE THERAPEUTICS
1/18/21
Smit M, Marinosci A, Agoritsas T, et al. | Clin Microbiol Infect
Aim: To review the evidence on a pre- and post-exposure prophylactic (PrEP and PEP) candidate for COVID-19.
CANDIDATE THERAPEUTICS
1/16/21
Lin Y, Chen C, Wu S | J Med Internet Res
Aim: To review the efficiency and quality of data collection in the existing literature.
1/15/21
Shareef MA, Bashaiwth HM, AlAkbari AO, et al. | Avicenna J Med
Aim: To review the evidence on SARS-CoV-2 and HIV coinfection.
CLINICAL CHARACTERISTICS
1/15/21
Mohamadi M, Goodarzi A, Aryannejad A, et al. | Med J Islam Repub Iran
Aim: To review the evidence on SARS-CoV-2 infection complications in elderly individuals.
CLINICAL CHARACTERISTICS
1/15/21
Cirillo N, Bizzoca ME, Lo Muzio E, et al. | Acta Odontol Scand
Aim: To collect comprehensive data on the taste alterations prevalence worldwide and, precisely, in 16 countries.
CLINICAL CHARACTERISTICS
1/15/21
Goldstein KM, Ghadimi K, Mystakelis H, et al. | VA Evidence Synthesis Program
Aim: To review the evidence on the risk of transmitting SARS-CoV-2, SARS, MERS, and influenza with administration of drugs via nebulizer
UPDATED
VA ESP
1/15/21
Xu W, Li X, Dozier M, et al. | J Glob Health
Aim: To investigate the extent of SARS-CoV-2 transmission in schools. 
UPDATED
INFECTION CONTROL
1/14/21
Zinellu A, Mangoini AA | J Clin Med
Aim: To review the evidence on the predictive role of the red blood cell distribution width (RDW), a routine hematological test, in patients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
1/14/21
???? P, ?????? H, ???????????? A, et al. | Russian Journal of Infection and Immunity
Aim: To determine the COVID-19 epidemiology, clinical features, diagnosis and treatment.
1/13/21
Hassanipour S, Faradonbeh SB, Momeni K, et al. | Int J Reprod Biomed
Aim: To investigate the clinical manifestation include signs and symptoms, laboratory results, and perinatal outcomes in pregnant women with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/13/21
Oshay RR, Chen MYC, Fields BKK, et al. | Clin Imaging
Aim: To conduct a comprehensive systematic review of all existing literature regarding imaging findings on chest CT and associated clinical features in pregnant patients diagnosed with COVID-19.
CLINICAL CHARACTERISTICS
1/13/21
Lee DS, Mirmirani P, McCleskey PE, et al. | Dermatol Online J
Aim: To identify case reports and case series characterizing cutaneous manifestations of confirmed COVID-19.
1/12/21
Soltani S, Tabibzadeh A, Zakeri A, et al. | Rev Neurosci
Aim: To systematically review the COVID-19 associated central nervous system manifestations, mental and neurological symptoms.
CLINICAL CHARACTERISTICS
1/12/21
Killikelly C, Lenferink LIM, Xie H, et al. | J Loss Trauma
Aim: To review the evidence on the psychological symptoms in healthcare workers during the COVID-19 pandemic.
MENTAL HEALTH
1/11/21
Israfil SMH, Sarker MMR, Rashid PT, et al. | Front Public Health
Aim: To summarize the global clinical characteristics of the COVID-19 patients systematically and identify their diagnostic challenges to help the medical practitioners properly diagnose and for better management of COVID-19 patients. 
CLINICAL CHARACTERISTICS
1/11/21
Caristia S, Ferranti M, Skrami E, et al. | Epidemiol Prev
Aim: To describe and compare the effectiveness of national and local lockdowns in controlling the spread of COVID-19.
INFECTION CONTROL
1/11/21
Hariyanto TI, Japar KV, Kwenandar F, et al. | Am J Emerg Med
Aim: To evaluate the difference between these parameters in severe and nonsevere disease and to provide the optimal cutoff value for predicting severe disease.
CLINICAL CHARACTERISTICS
1/11/21
Johanna N, Citrawijaya H, Wangge G | J Public Health Res
Aim: To evaluate the effectiveness of mass testing, lockdown, or a combination of both to control COVID-19 pandemic.
UPDATED
INFECTION CONTROL
1/11/21
Zhao X, Gang X, He G, et al. | Front Endocrinol
Aim: To compare the impacts of obesity on the severity and mortality of influenza and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/11/21
Fan S, Guan J, Cao L, et al. | Asian J Psychiatr
Aim: To investigate and monitor the mental health status of pregnant women during the COVID-19 pandemic.
MENTAL HEALTH
1/11/21
Kahil K, Cheaito MA, El Hayek R, et al. | Asian J Psychiatr
Aim: To synthesize descriptive and analytic evidence of suicide and suicide-related outcomes (ideations, intent, attempt, or completion) during major international respiratory outbreaks (COVID-19, MERS, SARS, and influenza A) in the recent history.
MENTAL HEALTH
1/11/21
Syeda HB, Syed M, Sexton KW, et al. | JMIR Med Inform
Aim: To conduct a systematic literature review on the role of ML as a comprehensive and decisive technology to fight the COVID-19 crisis in the arena of epidemiology, diagnosis, and disease progression.
UPDATED
DIAGNOSTICS
1/10/21
Lewis A, Frontera J, Placantonakis DG, et al. | J Neurol Sci
Aim: To review the literature on cerebrospinal fluid (CSF) testing in patients with COVID-19 for evidence of viral neuroinvasion by SARS-CoV-2.
CLINICAL CHARACTERISTICS
1/9/21
Mansourian M, Ghandi Y, Habibi D, et al. | Arch Pediatrie
Aim: To provide a meta-analysis of previously published papers on the COVID-19-related clinical features and laboratory findings in children.
CLINICAL CHARACTERISTICS
1/9/21
Wittenberg E, Goldsmith JV, Chen C, et al. | Patient Educ Couns
Aim: To determine the content of provider communication resources and peer-reviewed articles on COVID-19 communication in order to identify opportunities for developing future COVID-19 communication curricula and support tools.
1/8/21
Aminian A, Tu C, et al. | Obes Surg
Aim: To measure the association between history of bariatric surgery and the severity of COVID-19.
CLINICAL CHARACTERISTICS
1/8/21
Joo JY, Liu M | Int Nurs Rev
Aim: To identify and synthesize qualitative studies of frontline nurses’ experiences and challenges when caring for patients with COVID?19 in hospitals.
UPDATED
MENTAL HEALTH
1/8/21
Abubakar AR, Sani IH, Godman B, et al. | Infect Drug Resist
Aim: To summarize some evidence-based therapeutic options for COVID-19 infection.
1/7/21
Lin C, Tu P, Beitsch LM | Vaccines
Aim: To compare trends and synthesize findings in vaccination receptivity over time across US and international polls, assess survey design influences and evaluate context to inform policies and practices.
INFECTION CONTROL
1/7/21
Cuadra-Martínez D, Castro-Carrasco PJ, Sandoval-Díaz J, et al. | Rev Med Chil
Aim: To conduct a systematic review on psychological behavior in the context of pandemic scenarios during the twenty-first century. 
MENTAL HEALTH
1/7/21
Deng Y, Chen Y, Zhang B | Asian J Psychiatr
Aim: To evaluate the prevalence of depression and anxiety among general public and healthcare workers during COVID-19 in China and the changes of prevalence before and after the peak of the epidemic occurred.
MENTAL HEALTH
1/7/21
Lukito AA, Pranata R, Henrina J, et al. | Diabetes Metab Syndr
Aim: To review the evidence on metformin consumption and mortality in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
1/6/21
Islam MM, Poly TN, Walther BA, et al. | Front Med
Aim: To assess clinical manifestations and neonatal outcomes of pregnant women with COVID-19.
CLINICAL CHARACTERISTICS
1/6/21
Badawi A, Vasileva D | World J Clin Cases
Aim: To analyze and compare the profile of COVID-19 cases between China and North America as two regions that differ in many environmental, host and healthcare factors related to disease risk.
CLINICAL CHARACTERISTICS
1/6/21
Santos REA, da Silva MG, do Monte Silva MCB, et al. | Am J Otolaryngol
Aim: To conduct a systematic review of the literature to investigate the time of onset and duration of symptoms of loss of smell and taste in patients diagnosed with COVID-19.
CLINICAL CHARACTERISTICS
1/6/21
Andrade BS, Rangel FS, Santos NO, et al. | Front Pharmacol
Aim: To review the evidence on drug candidates, potentially approved to be used as new options for SARS-CoV-2 prophylaxis clinical trials and medical protocols. 
CANDIDATE THERAPEUTICS
1/6/21
Agrawal V, Yadav SK, Agarwal P, et al. | Indian Journal of Surgery
Aim: To appraise the quality of appropriate PPE recommendations and propose a strategy to optimize the PPE usage. 
INFECTION CONTROL
1/6/21
Lewis K, Chaudhuri D, Alshamsi F, et al. | PLoS One
Aim: To determine the efficacy and safety of hydroxychloroquine as prophylaxis for COVID-19.
CANDIDATE THERAPEUTICS
1/6/21
Zaffanello M, Piacentini G, Nosetti L, et al. | Transfus Apher Sci
Aim: To review the literature and ongoing clinical trials on convalescent plasma therapy in pediatric patients with COVID-19. 
CANDIDATE THERAPEUTICS
1/5/21
Hariyanto TI, Hardyson W, Kurniawan A | Drug Res
Aim: To give clear evidence regarding the potential benefit and safety of tocilizumab in improving the outcome of COVID-19 patients.
CANDIDATE THERAPEUTICS
1/5/21
Mishra P, Tomar A, Kumar A, et al. | Saudi Journal of Anaesthesia
Aim: To review the evidence on effective pain management in pediatric patients suffering from SARS-CoV-2 virus symptoms.
1/5/21
Benito DA, Bestourous DE, Tong JY, et al. | Otolaryngol Head Neck Surg
Aim: To determine the cumulative incidences of decannulation and mechanical ventilation weaning in patients with coronavirus disease 2019 (COVID-19) who have undergone a tracheotomy. 
CLINICAL CHARACTERISTICS
1/5/21
Hashemi-madani N, Emami Z, Janani L, et al. | Clin Imaging
Aim: To assess the relationship between different chest CT features and severity of clinical presentation in COVID-19.
CLINICAL CHARACTERISTICS
1/4/21
Alawna M, Amro M, Mohamed AA | Eur Rev Med Pharmacol Sci
Aim: To systematically analyze the effects of aerobic exercise on immunological biomarkers to provide safe aerobic exercise recommendations and specifications for patients with COVID-19.
CANDIDATE THERAPEUTICS
1/4/21
Post N, Eddy D, Huntley C, et al. | PLoS One
Aim: To comprehensively evaluate the evidence describing the antibody response to SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Rahimi NR, Fouladi-Fard R, Aali R, et al. | Environ Res
Aim: To highlight how the virus is impacted by the environment and how the virus has impacted the environment.
1/4/21
Rada G, Corbalan J, Rojas P, et al. | Medwave
Aim: To provide a timely, rigorous and continuously updated summary of the available evidence on the role of cell-based therapies in the treatment of patients with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
1/4/21
Khamis AH, Jaber M, Azar A, et al. | J Formos Med Assoc
Aim: To systematically review all COVID-19 publications to summarize the clinical features, assess comorbidities, prevalence, and disease outcomes.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Kim MS, An MH, Kim WJ, et al. | PLoS One
Aim: To evaluate the comparative efficacy and safety of pharmacological interventions used in treating COVID-19 and form a basis for an evidence-based guideline of COVID-19 management by evaluating the level of evidence behind each treatment regimen in different clinical settings. 
UPDATED
CANDIDATE THERAPEUTICS
1/4/21
Han Q, Guo M, Zheng Z, et al. | Front Pharmacol
Aim: To assess the safety and efficacy of anti-IL-6 signaling (anti-IL6/IL-6R/JAK) agents on COVID-19.
CANDIDATE THERAPEUTICS
1/4/21
Choupoo NS, Das SK, Haldar R, et al. | Indian J Crit Care Med
Aim:  To test the efficacy of different therapeutic options currently available for treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/4/21
Cascino F, Hoxhaj I, Zace D, et al.  | BMJ Glob Health
Aim: To identify healthcare systems interventions, experiences and recommendations that have been used to manage different respiratory viral infections outbreaks in the past.
UPDATED
1/4/21
Desai A, Gupta R, Advani S, et al. | Cancer
Aim: To assess the overall mortality in this population through a meta?analysis of published data on COVID?19 and cancer.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Fu L, Liu X, Su Y, et al. | Clin Cardiol
Aim: To investigate prevalence of cardiac injury and its impact on the outcomes in patients with COVID?19.
CLINICAL CHARACTERISTICS
1/4/21
Del Zompo F, De Siena M, Ianiro G, et al. | Eur Rev Med Pharmacol Sci
Aim: To systematically review the prevalence of liver involvement in patients with SARS-CoV-2 infection at their hospital admission, and its correlation with disease severity and clinical outcomes in patients with or without pre-existing chronic liver disease.
CLINICAL CHARACTERISTICS
1/4/21
Lee KH, Kim SJ, Hong SH, et al. | Eur Rev Med Pharmacol Sci
Aim: To analyze the same clinical issues through an improved research method and to find out the differences from the retracted papers.
1/4/21
Liu H, Yang D, Chen X, et al.  | Cancer Med
Aim: To qualify the potential effects of anticancer therapies on the clinical outcomes, such as mortality, admission to the intensive care unit (ICU), and the severity of COVID?19, in patients with cancer infected with COVID?19.
UPDATED
CLINICAL CHARACTERISTICS
1/4/21
Dillman A, Zoratti MJ, Park JJH, et al. | Infect Drug Resist
Aim: To summarize and characterize research efforts with respect to the different stages of disease progression.
1/3/21
Cheruiyot I, Sehmi P, Ngure B, et al.  | Langenbecks Arch Surg
Aim: To determine the presence of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in abdominal tissues or fluids and in surgical smoke.
UPDATED
INFECTION CONTROL
1/3/21
Cai R, Zhang J, Zhu Y, et al. | Int Urol Nephrol
Aim: To conduct a literature review and meta-analysis to understand the frequency of mortality among CKD patients infected with COVID-19.
CLINICAL CHARACTERISTICS
1/3/21
de Souza DB, de Oliveira Andrade A, Milagre ST, et al. | Research on Biomedical Engineering
Aim: To carry out a systematic review of the advantages and disadvantages of possible solutions in oxygenation support.
CANDIDATE THERAPEUTICS
1/2/21
Farrukh L, Mumtaz A, Sana MK | Rev Med Virol
Aim: To review the evidence on potential reasons why the results of the SARS?CoV?2 RT?PCR tests were positive again in recovered patients.
1/2/21
Liu N, Sun J, Wang X, et al. | Int J Infect Dis
Aim: To assess the association between low vitamin D status and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/2/21
Wynants L, Van Calster B, Bonten MMJ | BMJ
Aim: To review and critically appraise published and preprint reports of models that aim to predict either (i) presence of existing COVID-19 infection, or (ii) future complications in individuals already diagnosed with COVID-19
UPDATED
1/2/21
Salehi M, Amanat M, Mohammadi M, et al. | J Affect Disord
Aim: To assess the prevalence of PTSD related symptoms in coronavirus outbreaks.
MENTAL HEALTH
1/1/21
Dwipayana, I. D. A. P., Sutarini, I. D. A. A. D. | Jurnal Berkala Epidemiologi
Aim: To discuss the available options that can be taken to vaccinate immunosuppressed cancer patients when no vaccine is being developed for their safety.
1/1/21
Danet AD | Med Clin
Aim: To find out the psychological impact among first-line healthcare personnel in caring for patients with SARS-CoV-2 and to compare it with the rest of healthcare professionals.
MENTAL HEALTH
1/1/21
O'Leary T | J Molecular Diag
Aim: To better understand the relative performance characteristics of saliva and upper airway samples.
DIAGNOSTICS
12/31/20
Chowdhary A, Subedi R, Tandon M | Brain Sci
Aim: To collect, analyze, and summarize the neurological findings in the MRI among patients with COVID-19
CLINICAL CHARACTERISTICS
12/31/20
Tian T, Huo X | J Infect Dev Ctries
Aim: To review the evidence on the secondary attack rate of SARS-CoV-2.
CLINICAL CHARACTERISTICS
12/30/20
Mehraeen E, Alinaghi SAS, Nowroozi A, et al. | Indian Heart J
Aim: To pinpoint different observed ECG findings and discuss their clinical significance.
CLINICAL CHARACTERISTICS
12/30/20
McEwan T, Robinson PC | Semin Arthritis Rheum
Aim: To systematically examine infectious adverse events associated with colchicine usage and the clinical use of colchicine for infectious diseases.
CANDIDATE THERAPEUTICS
12/30/20
Lai X, Liu J, Zhang T, et al. | BMJ Open
Aim: To systematically assess the clinical, laboratory and imaging predictors as well as prediction models for severe or critical illness and mortality in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/30/20
de Oliveira TF, de Oliveira Rocha CA, dos Santos AGG, et al. | Braz J Cardiovasc Surg
Aim: To systematically review the literature on the use of extracorporeal membrane oxygenation (ECMO) in patients with coronavirus disease 2019 (COVID-19).
CANDIDATE THERAPEUTICS
12/30/20
Dorrell R, Dourgherty MK, Barash EL, et al. | JGH Open
Aim: To characterize the prevalence of gastrointestinal (GI) and hepatic involvement in COVID?19 and specifically assess the prevalence of GI symptoms in isolation.
UPDATED
CLINICAL CHARACTERISTICS
12/30/20
Verdejo C, Vergara-Merino L, Meza N, et al. | Medwave
Aim: To provide a timely, rigorous, and continuously updated summary of the evidence available on the role of macrolides for treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
12/30/20
Mondal R, Ganguly U, Deb S, et al. | J Neurovirol
Aim: To summarise the clinical profile, investigations and radiological findings among patients with SARS-CoV-2 associated meningoencephalitis.
UPDATED
CLINICAL CHARACTERISTICS
12/30/20
Brown WA, Moore EM, Watters DA | ANZ J Surg
Aim: To estimate the effect size of coronavirus disease 2019 (COVID-19) on post-operative mortality.
CLINICAL CHARACTERISTICS
12/30/20
Maharaj S, Alvarez MB, Mungul S, et al. | Laryngoscope Investig Otolaryngol
Aim: To describe otologic dysfunction in patients with the novel SARS?CoV?2.
CLINICAL CHARACTERISTICS
12/30/20
Al Maqbali M, Al Sinani M, Al-Lenjawi B | J Psychosom Res
Aim: To ascertain the present impact of the COVID-19 outbreak on the prevalence of stress, anxiety, depression and sleep disturbance among nurses.
UPDATED
MENTAL HEALTH
12/30/20
Panda PK, Gupta J, Chowdhury SR, et al. | J Trop Pediatr
Aim: To provide a pooled estimate of the prevalence of various psychological and behavioral symptoms/disorders in children and adolescents up to 18?years of age during this pandemic.
MENTAL HEALTH
12/30/20
SeyedAlinaghi S, Oliaei S, Kianzad S, et al. | World J Virol
Aim: To summarize the recent findings and reports of COVID-19 reinfection in patients previously reCoVered from the disease.
CLINICAL CHARACTERISTICS
12/30/20
Verdugo-Paiva F, Acuna MP, Sola I, et al. | Medwave
Aim: To provide a timely, rigorous and continuously updated summary of the evidence available on the role of remdesivir in the treatment of patients with COVID-19.
12/30/20
Callus E, Bassola B, Fiolo V, et al. | Front Psychol
Aim: To identify the most effective stress reduction techniques for health care providers dealing with patients infected with severe coronavirus (SARS, MERS, and COVID-19).
UPDATED
MENTAL HEALTH
12/30/20
Parsay S, Vosoughi A, Khabbaz A, et al. | J Stroke Cerebrovasc Dis
Aim: To investigate the incidence of ischemic CVA and the mortality due to it in the setting of COVID-19.
CLINICAL CHARACTERISTICS
12/28/20
Pranata R, Henrina J, Lim MA, et al. | Arch Gerontol Geriatr
Aim: To quantify the dose-response relationship between CFS and mortality in COVID-19 patients.
CLINICAL CHARACTERISTICS
12/28/20
Hassani NS, Shojaee A, Khodaprast Z, et al. | J Intensive Care Med
Aim: To investigate the echocardiographic features of cardiac injury related to COVID-19 and their prognostic value.
CLINICAL CHARACTERISTICS
12/28/20
Polychronis G, Roupa Z | J Public Aff
Aim: To review the evidence on health care workers' knowledge level during the spread of COVID-19 and their perception of the risk related to the COVID-19 pandemic.
INFECTION CONTROL
12/28/20
Aziz M, Goyal H, Haghbin H, et al. | Am J Med Sci
Aim: To evaluate the prevalence of “loss of smell” in COVID-19 as well as its utility for prognosticating the disease severity.
CLINICAL CHARACTERISTICS
12/28/20
Clement ND, Ng N, Simpson CJ, et al. | Bone Joint Res
Aim: To assess: 1) the prevalence of COVID-19 in hip fracture patients during the first wave of the pandemic; 2) the associated rate and risk of mortality compared to those without COVID-19; 3) the demographics associated with COVID-19-positive patients; 4) the time from the day of admission to diagnosis of COVID-19; and 5) length of follow-up after a diagnosis of COVID-19.
CLINICAL CHARACTERISTICS
12/23/20
Prendki V, Tau N, Avni T, et al. | BMC Geriatr
Aim: To examine the participation of elderly patients in therapeutic or prophylactic trials on COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
12/23/20
Birgand G, Peiffer-Smadja N, Fournier S, et al. | JAMA Netw Open
Aim: To review current evidence on air contamination with SARS-CoV-2 in hospital settings and the factors associated with contamination, including viral load and particle size.
INFECTION CONTROL
12/23/20
 | European Centre for Disease Prevention and Control
Aim: To provide an update on the knowledge surrounding the role of children in the transmission of SARS-CoV-2 and the role of schools in the COVID-19 pandemic, based on the experience in the EU from August–December, 2020. 
INFECTION CONTROL
12/23/20
Bhuiyan MU, Stiboy E, Hassan MZ, et al. | Vaccine
Aim: To review the evidence on the epidemiological and clinical characteristics of COVID-19 infection in children under five years.
UPDATED
CLINICAL CHARACTERISTICS
12/23/20
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the use of ivermectin for prophylaxis or treatment of COVID-19.
12/23/20
Kubota T, Gajera PK, Kuroda N | Epilepsy Behav
Aim: To perform a systematic review and meta-analysis to summarize and quantitatively evaluate the electroencephalogram (EEG) findings in patients with coronavirus disease 2019 (COVID-19).
12/23/20
Scheen AJ | Diabetes Metab
Aim: To investigate the impact of previous statin therapy in patients hospitalized for COVID-19.
CLINICAL CHARACTERISTICS
12/22/20
Ghazy RM, Almaghraby A, Shaaban R, et al. | Sci Rep
Aim: To review the evidence on the effectiveness and safety of either CQ or HCQ alone or in combination with AZM in treating COVID-19.
CANDIDATE THERAPEUTICS
12/22/20
Sun F, Zhu J, Tao H, et al. | J Psychosom Obstet Gynaecol
Aim: To review the evidence on mental health in pregnant and delivery women during the COVID-19 pandemic.
MENTAL HEALTH
12/22/20
Luo Y, Chua CR, Xiong Z, et al. | Front Psychiatry
Aim: To review the evidence on the impact of viral respiratory epidemics, including coronavirus disease 2019 (COVID-19), on mental health among different population groups, drawing on their insights for recommendations for the current COVID-19 pandemic.
MENTAL HEALTH
12/22/20
Piombino P, Troise S, Vargas M, et al. | Eur Rev Med Pharmacol Sci
Aim: To analyze the scientific literature identifying the indications for tracheostomy and safety precautions to reduce contamination.
CANDIDATE THERAPEUTICS
12/22/20
Fiest KM, Krewulak KD, Plotnikoff KM, et al. | BMC Med
Aim: To evaluate the validity of published triage protocols and the mortality prediction embedded within them to help inform health system-decision-making.
12/22/20
Oikonomidi T, Boutron I, Pierre O, et al. | BMC Med
Aim: To describe the proportion of evidence on the effect of interventions for COVID-19 from preprints and journal articles and map changes in evidence between and within different sources reporting on the same study.
CANDIDATE THERAPEUTICS
12/22/20
Neef V, Buxmann H, Rabenau HF, et al. | Pediatr Neonatal
Aim: To characterize a large number of neonates delivered by rRT-PCR confirmed SARS-CoV-2 positive mothers.
CLINICAL CHARACTERISTICS
12/22/20
Wang Y, Huo P, Dai R, et al. | Int Immunopharmacol
Aim: To evaluate the existing evidence and experience related to CP immunotherapy for COVID-19.
CANDIDATE THERAPEUTICS
12/22/20
Fabrizi F, Alfieri CM, Cerutti R, et al. | Pathogens
Aim: To evaluate the frequency of AKI and dialysis requirement in patients who underwent hospitalization due to COVID-19.
CLINICAL CHARACTERISTICS
12/22/20
Rocha APD, Atallah ÁN, Pinto ACPN, et al. | Sao Paulo Med J
Aim: To assess whether patients undergoing pharmacological treatment for IMID present higher risk of worse outcomes when diagnosed with COVID-19.
CLINICAL CHARACTERISTICS
12/22/20
Clark M, Loshak H, Farrah K | CADTH
Aim: To review the evidence on the use of COVID-19 mRNA vaccines on patients with cancer or who are immunocompromised.
12/22/20
Rattka M, Dreyhaupt J, Winsauer C, et al. | Heart
Aim: To assess the mortality of patients with STEMI admitted during the COVID-19 pandemic.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Bae S, Kim SR, Kim M, et al.  | Heart
Aim: To estimate the prevalence and risk factors for CVD among patients with COVID-19 in different age groups.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Sarkar S, Khanna P, Singh A | J Med Virol
Aim: To evaluate the consequence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in patients with concurrent co-infections based on the publications reported to date.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Octavius GS, Silviani FR, Lesmandjaja A, et al. | Middle East Current Psychiatry
Aim: To analyze the impact of COVID-19 towards adolescents’ mental health.
MENTAL HEALTH
12/22/20
Tyrrell CSB, Mytton OT, Gentry SV, et al. | Thorax
Aim: To provide acute insights into the guidance on which patients are treated in ICU and receive ventilation during periods of high demand for ICU capacity during the COVID-19 pandemic.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Raymond C, Loshak H | CADTH
Aim: To describe the trial characteristics and estimated primary completion dates of the ongoing phase II, phase III, and phase IV studies evaluating IVIg and hyperimmune globulin to treat COVID-19.
UPDATED
12/22/20
Mathioudakis AG, Fally M, Hashad R, et al. | Life
Aim: To describe the outcomes evaluated in 415 RCTs on the management of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Rabbani G, Islam SMS, Rahman MA, et al. | Expert Rev Respir Med
Aim: To investigate COVID-19 mortality and severity among patients with pre-existing COPD.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Rodrigues C, Baía I, Domingues R, et al. | Front Public Health
Aim: To review knowledge on the impact of COVID-19 on pregnancy and describe the outcome of published cases of pregnant women diagnosed with COVID-19, as well as the characteristics of COVID-19 positive women who delivered in Portugal by 31 of March 2020. 
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Santabárbara J, Lasheras I, Lipnicki DM, et al. | Prog Neuropsychopharmacol Biol Psychiatry
Aim: To conduct a systematic review and meta-analysis to ascertain the impact of the COVID-19 outbreak on the prevalence of anxiety in the general population.
MENTAL HEALTH
12/22/20
July J, Pranata R | Geriatr Gerontol Int
Aim: To discover whether age, sex and other comorbidities might affect the association between dementia and mortality.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Islam MA, Alam SS, Kundu S, et al. | Front Neurol
Aim: To conduct a comprehensive systematic review and meta-analysis to estimate the overall pooled prevalence of headache in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Violant-Holz V, Gallego-Jimenez MG, Gonzalez-Gonzalez CS, et al. | Int J Environ Res Public Health
Aim: To analyze the extent to which engaging in physical activity during the COVID-19 pandemic affected adults’ psychological health.
MENTAL HEALTH
12/22/20
West E, Moore K, Kupeli N, et al. | Age Aging
Aim: To explore key factors that influence place of care and place of death decisions in older adults.
12/22/20
Lee MMY, Docherty KF, Sattar N, et al. | Eur Heart J Cardiovasc Pharmacother
Aim: To provide summary odds ratio (OR) estimates for associations between treatment with (vs. without) renin-angiotensin system (RAS) blockers and risk of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection and coronavirus disease 2019 (CoViD-19) severity (including case-fatality) in patients with hypertension, and in all patients (irrespective of hypertension).
CANDIDATE THERAPEUTICS
12/22/20
Viner RM, Ward J, Hudson L, et al. | Arch Dis Child
Aim: To undertake a systematic review of reviews of the prevalence of symptoms and signs of COVID-19 in those aged under 20 years.
UPDATED
CLINICAL CHARACTERISTICS
12/22/20
Subsoontorn P, Lohitnavy M, Kongkaew C | Sci Rep
Aim: To determine the accuracy of nucleic acid point-of-care diagnosis for human coronaviruses, particularly, SARS-CoV, MERS-CoV and SARS-CoV-2.
U