COVID-19 Evidence Reviews
as of 8/13/20
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Clinical Characteristics
 
= living review
= draft/preprint   |  
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
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8/3/20
Shao M, Li X, Liu F, et al. | Pharmacol Res
Aim: To investigate whether the presence of acute kidney injury (AKI) might increase the risk of severe infection and fatality in COVID-19 patients.
CLINICAL CHARACTERISTICS
8/3/20
Wu B, Gu D, Yu J, et al. | Infect Genet Evol
Aim: To delve into the association between ABO blood group and COVID-19 infection, severity and demise.
CLINICAL CHARACTERISTICS
8/3/20
Carlo D, Montemurro N, Petrella G, et al. | J Neurol
Aim: To review the evidence on the spectrum of neurological symptoms experienced by COVID-19 patients.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
8/3/20
Zuin M, Rigatelli G, Zuliani G, et al. | J Cardiovasc Med
Aim: To investigate the relationship between ACI and mortality risk in COVID-19 patients.
CLINICAL CHARACTERISTICS
8/3/20
Rocke J, Hopkins C, Philpott C, et al. | Clin Otolaryngol
Aim: To systematically review the currently available evidence investigating the association between olfactory dysfunction (OD) and the novel coronavirus (COVID-19).
CLINICAL CHARACTERISTICS
8/3/20
Kotlyar A, Grechukihina O, Chen A, et al | Am J Obstet Gynecol
Aim: To determine estimates of vertical transmission of COVID-19 based upon early RNA detection of SARS-CoV-2 after birth from various neonatal/fetal sources and neonatal serology.
CLINICAL CHARACTERISTICS
8/2/20
de Siqueira JVV, Almeida LG, Zico BO | Obes Res Clin Pract
Aim: To assess whether there was an association between obesity and higher levels of hospitalization, poor outcomes and mortality due to the disease of novel coronavirus (COVID-19).
CLINICAL CHARACTERISTICS
8/2/20
Rooney S, Webster A, Paul L | Phys Ther
Aim: To 1) compare physical function and fitness outcomes in people infected with SARS-CoV to healthy controls; 2) quantify the recovery of physical function and fitness following SARS-CoV infection; 3) determine the effects of exercise following SARS-CoV infection.
CLINICAL CHARACTERISTICS
8/1/20
Qiu P, Zhou Y, Wang F, et al. | Aging Clin Exp Res
Aim: To find risk factors for the COVID-19-related death, helping to enhance the efficacy and reduce the mortality of COVID-19.
CLINICAL CHARACTERISTICS
8/1/20
Awulachew E, Diriba K, Anja A, et al. | Radiol Res Pract
Aim: To systematically analyze the existing literature on CT imaging features of patients with COVID-19 pneumonia.
CLINICAL CHARACTERISTICS
8/1/20
Mirzaei H, McFarland W, Karamouzian M, et al. | AIDS Behav
Aim: To review the evidence on the earliest patients with COVID-19-HIV co-infection.
CLINICAL CHARACTERISTICS
8/1/20
Baradaran A, Ebrahimzadeh MH, Baradaran A, et al. | Arch Bone Jt Surg
Aim: To assess the prevalence of comorbidities in the confirmed COVID-19 patients.
CLINICAL CHARACTERISTICS
8/1/20
Akbari H, Tabrizi R, Lankarani KB, et al. | Life Sci
Aim: To make a comparison between the clinical laboratory-related factors, complete blood count (CBC) indices, cytokines, and lymphocyte subsets in order to distinguish severe coronavirus disease 2019 (COVID-19) cases from the non-severe ones.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
7/31/20
Akhtar H, Patel C, Abuelgasim E, et al. | Gynecol Obstet Invest
Aim: To review published studies related to the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections with pregnancy, foetal, and neonatal outcomes during coronavirus disease 2019 (COVID-19) pandemic.
CLINICAL CHARACTERISTICS
7/30/20
Zhou Y, Yang Q, Chi J, et al. | Int J Infect Dis
Aim: To evaluate the association between different comorbidities and the severity of Covid-19.
CLINICAL CHARACTERISTICS
7/30/20
Figliozzi S, Masci P, Ahmadi N, et al. | Eur J Clin Invest
Aim: To review available evidence and provide pooled estimates on predictors of clinical outcomes in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/29/20
Yasuhara J, Kuno T, Takagi H, et al. | Pediatr Pulmonol
Aim: To investigate the clinical characteristics of COVID-19 in children.
CLINICAL CHARACTERISTICS
7/29/20
Liao S, Shao S, Chen Y, et al. | Crit Care
Aim: To review the evidence on severe complications of COVID-19 associated with coagulation changes, mainly characterized by increased D-dimer and fibrinogen levels with higher thrombosis risk, in particular pulmonary embolism (PE).
CLINICAL CHARACTERISTICS
7/28/20
Rao SN, Manissero D, Steele VR, et al. | Infect Dis Ther
Aim: To review available knowledge on correlations between SARS-COV-2 Ct values and patient- or healthcare-related outcomes to determine whether Ct values provide useful clinical information.
CLINICAL CHARACTERISTICS
7/28/20
Langford B, So M, Raybardhan S, et al. | Clin Microbiol Infect
Aim: To determine the prevalence of bacterial co-infection (at presentation) and secondary infection (after presentation) in patients with COVID-19.
CLINICAL CHARACTERISTICS
7/28/20
Li X, Pan X, Li Y, et al. | Crit Care
Aim: To comprehensively evaluate the impact of cardiac injury and its related biomarkers on mortality and other prognosis in patients infected with SARS-CoV-2.
CLINICAL CHARACTERISTICS
7/28/20
Capobianco G, Saderi L, Aliberti S, et al. | Eur J Obstet Gynecol Reprod Biol
Aim: To assess the risk of clinical complications in pregnant women and neonates infected with SARS-CoV-2.
CLINICAL CHARACTERISTICS
7/28/20
Abdi A, Jalilian M, Sarbarzeh PA, et al. | Diabetes Res Clin Pract
Aim: To summarize the evidence about diabetes and COVID-19 outbreak through a systematic review and meta-analysis approach.
CLINICAL CHARACTERISTICS
7/28/20
Malik VS, Ravindra K, Attri SV, et al. | Environ Sci Pollut Res Int
Aim: To examine the emerging evidence to identify an association between body mass index (BMI) and COVID-19 disease outcome.
CLINICAL CHARACTERISTICS
7/28/20
Wu Y, Li H, Guo X, et al. | Hepatol Int
Aim: To explore the incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 patients.
CLINICAL CHARACTERISTICS
7/28/20
Kovalic AJ, Satapathy SK, Thuluvath PJ | Hepatol Int
Aim: To determine the prevalence of CLD in patients with COVID-19 and their clinical outcomes.
CLINICAL CHARACTERISTICS
7/28/20
Weiss A, Jellingso M, Sommer MOA | EBioMedicine
Aim: To conduct a coherent overview of the duration of viral detection and viral RNA load in COVID-19 patients, stratified by specimen type, clinical severity, and age.
CLINICAL CHARACTERISTICS
7/24/20
Lin J, Yan H, Chen H, et al. | J Med Virol
Aim: To review the blood coagulation indicators in severe COVID?19 patients.
CLINICAL CHARACTERISTICS
7/24/20
Ceravolo MG, Arienti C, De Sire A, et al. | Eur J Phys Rehabil Med
Aim: To gather and present the current evidence informing rehabilitation of patients with COVID-19 and/or describing the consequences due to the disease and its treatment.
CLINICAL CHARACTERISTICS
7/23/20
de Melo GC, de Araujo KCGM | Cad Saude Publica
Aim: To analyze whether COVID-19 in pregnant women is related to premature birth and birth weight, and to summarize the diagnostic results of neonates born to mothers with COVID-19 for investigating the possibility of vertical transmission.
CLINICAL CHARACTERISTICS
7/23/20
Taherifard E, Taherifard E | Neurol Res
Aim: To systematically review the neurological complications in patients with SARS-CoV-2 infection and the methods used to diagnose both neurological complications and coronavirus infection.
CLINICAL CHARACTERISTICS
7/23/20
Deniz M, Tezer H | J Matern Fetal Neonatal Med
Aim: To review the current evidence on the vertical transmission of SARS CoV-2.
CLINICAL CHARACTERISTICS
7/22/20
Chen X, Laurent S, Onur OA, et al. | J Neurol
Aim: To study the frequency of neurological symptoms and complications in COVID-19 patients in a systematic review of the literature.
CLINICAL CHARACTERISTICS
7/21/20
Ashraf MA, Keshavarz P, Hosseinpour P, et al. | J Reprod Infertil
Aim: To demonstrate the effects of COVID-19 on pregnant women and the possibility of vertical transmission.
CLINICAL CHARACTERISTICS
7/21/20
Kovalic AJ, Huang G, Thuluvath PJ, et al. | Hepatology
Aim: To further characterize liver injury and other unique clinical characteristics across COVID-19 severity.
CLINICAL CHARACTERISTICS
7/21/20
Lim MA, Pranata R, Huang I, et al. | Can J Kidney Health Dis
Aim: To investigate the association between several complications, including acute kidney injury (AKI), acute liver injury (ALI), and coagulopathy, with poor outcomes in COVID-19.
CLINICAL CHARACTERISTICS
7/21/20
He J, Guo Y, Mao R, et al. | J Med Virol
Aim: To systematically review the characteristics of asymptomatic infection in the coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
7/21/20
Kumar J, Meena J, Yadav A, et al. | J Trop Pediatr
Aim: To compile the radiological findings of COVID-19 pneumonia in children in a systematic manner.
CLINICAL CHARACTERISTICS
7/21/20
Bajwa H, Riaz Y, Ammar M, et al. | Cureus
Aim: To analyze the published data on kidney injuries in COVID-19 and mortality rates in these patients.
CLINICAL CHARACTERISTICS
7/20/20
Gao Y, Liu M, Chen Y, et al. | J Med Virol
Aim: To assess whether tuberculosis is associated with an increased risk of severe disease and death in patients with COVID-19.
CLINICAL CHARACTERISTICS
7/20/20
Egbert AR, Cankurtaran S, Karpiak S | Brain Behav Immun
Aim: To synthesize early data on typology and topography of brain abnormalities in adults with COVID-19 in acute/subacute phase.
CLINICAL CHARACTERISTICS
7/20/20
Tian Y, Qiu X, Wang C, et al. | Int J Cancer
Aim: To review the evidence on cancer prevalence in patients with COVID-19, and examine the association of cancer with severe events.
CLINICAL CHARACTERISTICS
7/20/20
Pei Y, Liu W, Masokano IB, et al. | J Infect Public Health
Aim: To investigate the differences in the clinical manifestations and imaging characteristics between Chinese children and adults with COVID-19 by systematically analyzing the data derived from some latest literatures.
CLINICAL CHARACTERISTICS
7/19/20
Pormohammad A, Ghorbani S, Baradaran B, et al. | Microb Pathog
Aim: To evaluate the clinical features and laboratory findings using a large sample size of COVID-19 infected patients in order to assist in its understanding, prevention and treatment.
UPDATED
CLINICAL CHARACTERISTICS
7/19/20
Zarifian A, Birdary MZ, Arekhi S, et al. | J Med Virol
Aim: To review the evidence on gastrointestinal and liver manifestations of COVID-19 patients.
CLINICAL CHARACTERISTICS
7/19/20
Chen Y, Shao S, Lai EC, et al. | Crit Care
Aim: To compare the mortality rate in patients with SARS, MERS, and COVID-19 who developed acute kidney injury.
CLINICAL CHARACTERISTICS
7/19/20
Abdullahi A, Candan SA, Abba MA, et al. | Front Neurol
Aim: To summarize the evidence on the neurological and musculoskeletal symptoms of the disease.
CLINICAL CHARACTERISTICS
7/19/20
Foldi M, Farkas N, Kiss S, et al. | Obes Rev
Aim: To examine whether obesity is a risk factor for the critical condition in COVID?19 patients by performing a meta?analysis.
CLINICAL CHARACTERISTICS
7/18/20
Cooper TJ, Woodward BL, Harky A | HIV Med
Aim: To systematically review current studies reporting on clinical outcomes in people living with HIV (PLHIV) infected with severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2).
CLINICAL CHARACTERISTICS
7/18/20
Ghayda RA, Lee J, Lee JY, et al. | Int J Environ Res Public Health
Aim: To perform a novel systematic review and meta-analysis focusing on findings about correlations between clinical characteristics and laboratory features of patients with COVID-19.
CLINICAL CHARACTERISTICS
7/18/20
Yadav DK, Singh A, Zhang Q, et al. | Gut
Aim: To perform a meta-analysis to estimate the prognosis of patients with COVID-19 stratified according to liver injury. 
CLINICAL CHARACTERISTICS
7/17/20
Galbadage T, Peterson BM, Awada J, et al. | Front Med
Aim: To examine the association between male sex and COVID-19 severity.
UPDATED
CLINICAL CHARACTERISTICS
7/16/20
Liu J, Cui M, Yang T, et al. | BMJ Open Gastroenterol
Aim: To study the correlation between gastrointestinal (GI) symptoms and disease severity in patients with COVID-19.
CLINICAL CHARACTERISTICS
7/16/20
Shah S, Shah K, Patel SB, et al. | Cardiol Rev
Aim: To investigate the prognostic role of D-dimer in COVID-19 infected patients. 
UPDATED
CLINICAL CHARACTERISTICS
7/15/20
Zaki N, Alashwal H, Ibrahim S | Diabetes Metab Syndr
Aim: To undertake a review and critical appraisal of published/preprint reports that offer methods of determining the effects of hypertension, diabetes, stroke, cancer, kidney issues, and high-cholesterol on COVID-19 disease severity. 
CLINICAL CHARACTERISTICS
7/15/20
Collantes ME, Espiritu AI, Sy MCC, et al. | Can J Neurol Sci
Aim: To determine the neurological 48 manifestations and complications in COVID-19.
CLINICAL CHARACTERISTICS
7/14/20
Patel RS, Patel N, Baksh M, et al. | Cureus
Aim: To summarize the transmission and pathology of 2019-nCoV, and demographics, clinical presentation, laboratory, and chest imaging findings, along with treatment and outcomes in 2019-nCoV pneumonia patients.
CLINICAL CHARACTERISTICS
7/14/20
Fang X, Li S, Yu H, et al. | Aging
Aim: To systematically collect and evaluate the associations of epidemiological, comorbidity factors with the severity and prognosis of coronavirus disease 2019 (COVID-19).
CLINICAL CHARACTERISTICS
7/14/20
Bajgain KT, Badal S, Bajgain BB, et al. | Am J Infect Control
Aim: To explore the prevalence of top global comorbidities (CVD, Diabetes, COPD, Cancer, and CKD) among individuals with COVID-19, as well as investigate any significant associations.
CLINICAL CHARACTERISTICS
7/13/20
Momtazmanesh S, Shobeiri P, Hanaei S, et al. | Egypt Heart J
Aim: To define the clinical, electrocardiographic, and pathologic spectrum of cardiovascular disease (CVD), frequency of elevated cardiac and inflammatory biomarkers, and their frequency and relationship with severity of the disease and mortality in COVID-19 patients and to develop a triage risk stratification tool (TRST) that can serve as a guide for the timely recognition of the high-risk patients and mechanism-targeted therapy. 
CLINICAL CHARACTERISTICS
7/13/20
Tan Y, Goh C, Leow AST, et al. | J Thromb Thrombolysis
Aim: To characterize the clinical characteristics, neuroimaging findings, and outcomes of AIS in COVID-19 patients. 
CLINICAL CHARACTERISTICS
7/13/20
Nepal G, Rehrig JH, Shrestha GS, et al. | Crit Care
Aim: To inform and improve decision-making among the physicians treating COVID-19 by presenting a systematic analysis of the neurological manifestations experienced within these patients.
CLINICAL CHARACTERISTICS
7/13/20
Manabe T, Akatsu H, Kotani K, et al. | Respir Investig
Aim: To elucidate the clinical features of COVID-19 using a meta-analysis with a stratified analysis according to the timeline and the changes in the exposure risks before the disease was declared as a pandemic.
CLINICAL CHARACTERISTICS
7/11/20
Shafi AMA, Shaikh SA, Shirke MM, et al. | J Card Surg
Aim: To systematically review the current published literature on the different cardiac manifestations and the use of cardiac?specific biomarkers in terms of their prognostic value in determining clinical outcomes and correlation to disease severity.
CLINICAL CHARACTERISTICS
7/11/20
Abate S, Ali S, Mantedafro B, et al. | PLoS One
Aim: To investigate the rate of ICU admission, mortality, morbidity, and complications among patients with coronavirus.
UPDATED
CLINICAL CHARACTERISTICS
7/11/20
Moreno G, Carbonell R, Bodi M, et al. | Med Intensiva
Aim: To define the role of D-dimer in the disease, the prevalence of DIC and the usefulness of anticoagulant treatment in these patients.
CLINICAL CHARACTERISTICS
7/10/20
Kunutsor S, Laukkanen J | Ann Med
Aim: To evaluate renal complications of COVID-19 and their incidence using a systematic meta-analysis.
UPDATED
CLINICAL CHARACTERISTICS
7/9/20
Farsalinos K, Barbouni A, Poulas K, et al. | Ther Adv Chronic Dis
Aim: To examine the prevalence and effects of current smoking on adverse outcomes among hospitalized COVID-19 patients.
CLINICAL CHARACTERISTICS
7/9/20
Trocado V, Silvestre-Machado J, Azevedo L, et al. | J Matern Fetal Neonatal Med
Aim: To evaluate the impact of COVID-19 during pregnancy.
CLINICAL CHARACTERISTICS
7/9/20
Fontana P, Casini A, Robert-Ebadi H, et al. | Swiss Med Wkly
Aim: To summarise the reported risk of VTE associated with COVID-19 infections and to summarise guidance documents on thromboprophylaxis in COVID-19 patients, in a systematic review.
CLINICAL CHARACTERISTICS
7/8/20
Lvliang L, Zhong W, Bian Z, et al. | J Infect
Aim: To compare mortality risk factors of COVID-19, Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) to provide new strategies for COVID-19 prevention and treatment.
CLINICAL CHARACTERISTICS
7/8/20
Nandy K, Salunke A, Pathak SK, et al. | Diabetes Metab Syndr
Aim: To evaluate the impact of various morbidities on serious events in COVID 19.
CLINICAL CHARACTERISTICS
7/8/20
Seirafianpour F, Sodagar S, Mohammad AP, et al. | Dermatol Ther
Aim: To present an overview of suggestive skin manifestations of the COVID-19 and to address several considerations in the dermatological issues practices, during this pandemic.
CLINICAL CHARACTERISTICS
7/8/20
Kulkarni A, Kumar P, Tevethia HV, et al. | Aliment Pharmacol Ther
Aim: To assess the prevalence of CLD, the incidence of elevated liver chemistries and the outcomes of patients with and without underlying CLD/elevated liver chemistries in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/8/20
Pan D, Sze S, Minhas J, et al. | EClinicalMedicine
Aim: To assess whether ethnicity has been reported in patients with COVID-19 and its relation to clinical outcomes.
UPDATED
CLINICAL CHARACTERISTICS
7/7/20
Rokkas T | Ann Gastroenterol
Aim: To review the evidence on the involvement of the digestive system in COVID-19.
CLINICAL CHARACTERISTICS
7/6/20
Kumar-M P, Mishra S, Jha DK, et al. | Hepatol Int
Aim: To systematically study the occurrence of liver injury in COVID-19 and also determine the frequency of liver involvement in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/6/20
Borsetto D, Hopkins C, Philips V, et al. | Rhinology
Aim: To systematically assess the prevalence of self-reported altered sense of smell or taste in patients with confirmed SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
7/6/20
Al-Sadeq DW, Nasrallah GK | Int J Infect Dis
Aim: To systematically review the published literature on SARS-CoV-2 in the asymptomatic patients to estimate the incidence of COVID-19 among asymptomatic cases, as well as describe its epidemiological and clinical significance.
CLINICAL CHARACTERISTICS
7/4/20
Aziz M, Fatima R, Haghbin H, et al. | Inflamm Bowel Dis
Aim: To better understand the incidence and outcomes of COVID-19 in infammatory bowel disease (IBD) patients.
CLINICAL CHARACTERISTICS
7/2/20
Potere N, Valeriani E, Candeloro M, et al. | Crit Care
Aim: To summarize the evidence on clinically relevant outcomes in hospitalized patients with COVID-19.
CLINICAL CHARACTERISTICS
7/1/20
Altmayer S, Zanon M, Pacini GS, et al. | Eur Radiol
Aim: To compare the chest computed tomography (CT) findings of coronavirus disease 2019 (COVID-19) to other non-COVID viral pneumonia.
CLINICAL CHARACTERISTICS
7/1/20
Koh J, Shah SU, Chua PEY, et al. | Front Med
Aim: To review the epidemiological and clinical characteristics of COVID-19 cases in the early phase of the COVID-19 pandemic.
CLINICAL CHARACTERISTICS
7/1/20
Katal S, Balakrishnan S, Gholamrexanezhad A | J Neuroradiol
Aim: To review the available imaging findings of patients diagnosed with neurological symptoms associated with coronavirus infections.
CLINICAL CHARACTERISTICS
7/1/20
Yang J, Hu J, Zhu C | J Med Virol
Aim: To explore the relationship between obesity and COVID-19.
CLINICAL CHARACTERISTICS
6/30/20
Hu CLH, Raval M, Schnall JA, et al. | Pediatr Infect Dis J
Aim: To determine the average shedding times of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via the respiratory and gastrointestinal tracts in children.
CLINICAL CHARACTERISTICS
6/30/20
Khalili M, Karamouzian M, Nasiri N, et al. | Epidemiol Infect
Aim: To synthesize case fatality rate (CFR) among confirmed COVID-19 patients, incubation period, and time from onset of COVID-19 symptoms to first medical visit, intensive care unit (ICU) admission, recovery and death.
CLINICAL CHARACTERISTICS
6/30/20
Armstrong RA, Kane AD, Cook TM | Anaesthesia
Aim: To assess the reported ICU mortality for patients with confirmed COVID?19.
UPDATED
CLINICAL CHARACTERISTICS
6/28/20
Zhao Q, Fang X, Pang Z, et al. | J Eur Acad Dermatol Venereol
Aim: To gain an in-depth understanding of COVID-19 by summarizing publications related to the cutaneous manifestations of the disease and the ACE2 expression in skin tissues.
CLINICAL CHARACTERISTICS
6/27/20
Matar R, Oules B, Sohier P, et al. | J Eur Acad Dermatol Venereol
Aim: To analyze our experience in a French referral center and to perform a systematic review of the literature to evaluate the incidence and prognosis of cutaneous lesions observed in COVID?19 patients. 
CLINICAL CHARACTERISTICS
6/27/20
Gengler I, Wang JC, Speth MM, et al. | Laryngoscope Investig Otolaryngol
Aim: To synthesize existing scientific evidence on the role of sinonasal pathophysiology in COVID?19.
CLINICAL CHARACTERISTICS
6/26/20
Meena J, Yadav J, Saini L, et al. | Indian Pediatr
Aim: To synthesize the information on clinical manifestations, laboratory findings, and outcome of COVID-19 among the pediatric population.
CLINICAL CHARACTERISTICS
6/26/20
Feng X, Li S, Sun Q, et al. | Front Med
Aim: To explore the effect of risk factors on the severity of the disease, focusing on immune-inflammatory parameters, which represent the immune status of patients.
CLINICAL CHARACTERISTICS
6/26/20
da Costa KVT, Carnauba ATL, Rocha KW, et al. | Braz J Otorhinolaryngol
Aim: To identify evidence in the scientific literature about olfactory/gustatory disorders, their clinical presentation, prevalence and possible specific treatments associated with COVID-19.
CLINICAL CHARACTERISTICS
6/25/20
Tahvildari A, Arbabi M, Farsi Y, et al. | Front Med
Aim: To characterize the clinical, diagnostic, and treatment characteristics of patients presenting with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/24/20
Polak SB, Van Gool IC, Cohen D, et al. | Mod Pathol
Aim: To increase our understanding of COVID-19 pathophysiology by constructing a timeline and correlating histopathological findings with clinical stages of COVID-19. 
CLINICAL CHARACTERISTICS
6/24/20
Matar R, Alrahamani L, Monzer N, et al. | Clin Infect Dis
Aim: To describe the clinical characteristics and perinatal outcomes of COVID-19 in pregnancy.
CLINICAL CHARACTERISTICS
6/24/20
Trippella G, Ciarcia M, Ferrari M, et al. | Pathogens
Aim: To provide a comprehensive overview of all the available data regarding clinical features, outcomes, and management of pregnant women with COVID-19. 
CLINICAL CHARACTERISTICS
6/24/20
Pinzon RT, Wijaya VO, Buana RB, et al. | Front Neurol
Aim: To understand the neurologic characteristic of the disease and help physicians with early diagnosis and management.
CLINICAL CHARACTERISTICS
6/24/20
Grant MC, Geoghegan L, Arbyn M, et al. | PLoS One
Aim: To determine the prevalence of symptoms associated with COVID-19 worldwide.
CLINICAL CHARACTERISTICS
6/23/20
Baksh M, Ravat V, Zaidi A, et al. | Cureus
Aim: To summarize the clinical presentation, laboratory and chest imaging findings, management protocols, and outcome of ARDS in COVID-19-positive patients.
CLINICAL CHARACTERISTICS
6/23/20
Wang Z, Zhou Q, Wang C, et al. | Ann Transl Med
Aim: To review the clinical characteristics of children with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/23/20
Huang D, Lian X, Song F, et al. | Ann Transl Med
Aim: To identify and treat the severe and critical patients with COVID-19 is the key clinical problem to be solved.
CLINICAL CHARACTERISTICS
6/23/20
Alnor A, Sandberg MB, Gils C, et al. | J Appl Lab Med
Aim: To examine which routine laboratory tests are associated with severe COVID-19 disease.
CLINICAL CHARACTERISTICS
6/23/20
Singh AK, Gillies CL, Singh R, et al. | Diabetes Obes Metab
Aim: To estimate the prevalence of both cardiometabolic and other co?morbidities in patients with COVID?19 infection, and to estimate the increased risk of severity and mortality in people with co?morbidities.
CLINICAL CHARACTERISTICS
6/22/20
Hoang MP, Kanjanaumporn J, Aeumjaturapat S, et al. | Asian Pac J Allergy Immunol
Aim: To review the associations of olfactory and gustatory dysfunctions with COVID-19 which will be useful for early diagnosis and self-isolation. 
CLINICAL CHARACTERISTICS
6/21/20
Kronbichler A, Kresse D, Yoon S, et al. | Int J Infect Dis
Aim: To summarize the presentation of asymptomatic COVID-19 infections.
CLINICAL CHARACTERISTICS
6/20/20
Shelmerdine S, Lovrenski J, Caro-Dominguez P, et al. | Pediatr Radiol
Aim: To systematically review available literature regarding imaging findings in paediatric cases of COVID-19.
CLINICAL CHARACTERISTICS
6/20/20
Raba AA, Abobaker A, Elgenaidi IS, et al. | Acta Pediatr
Aim: To evaluate the clinical characteristics of COVID?19 in neonates and children under one year of age.
CLINICAL CHARACTERISTICS
6/20/20
Yang X, Jin Y, Li R, et al. | Crit Care
Aim: To assess the prevalence of abnormal urine analysis and kidney dysfunction in COVID-19 patients and to determine the association of acute kidney injury (AKI) with the severity and prognosis of COVID-19 patients.
CLINICAL CHARACTERISTICS
6/20/20
Sacco G, Briere O, Asfar M, et al. | Geriatr Psychol Neurosychiatr Vieil
Aim: To identify, from international literature, the most common symptoms met in older adults infected with the SARS-CoV-2 virus.
CLINICAL CHARACTERISTICS
6/20/20
Xuefeng M, Shouseng L, Chen L, Zhuang L, et al. | J Med Virol
Aim: To investigate the clinical features of pediatric inpatients with SARS-CoV-2 infection.
CLINICAL CHARACTERISTICS
6/19/20
Latalska M, Mackiewicz J | Ann Agric Environ Med
Aim: To review the evidence of ocular pathologies in asymptomatic COVID-19 patients.
CLINICAL CHARACTERISTICS
6/18/20
Chen Y, Shao S, Hsu C, et al. | Crit Care
Aim: To quantify the incidence of acute kidney injury in COVID-19 patients.
CLINICAL CHARACTERISTICS
6/18/20
Chung TW, Sridhar S, Zhang AZ, et al. | Open Forum Infect Dis
Aim: To review the evidence on olfactory disturbances in COVID-19 patients.
CLINICAL CHARACTERISTICS
6/14/20
Velev V, Popov M, Velikov P, et al. | Infez Med
Aim: To describe the incidence and type of the gastrointestinal injury (GI) in COVID-19, as well as their prognostic value.
CLINICAL CHARACTERISTICS
6/14/20
Yamada T, Wakabayashi M, Yamaji T, et al. | Clin Chim Acta
Aim: To investigate the association between severe COVID-19 and a change in white blood cell (WBC) count, an elevation of C-reactive protein (CRP), and fever, and to evaluate the diagnostic accuracy of leukocytosis and an elevation of CRP.
CLINICAL CHARACTERISTICS
6/13/20
Xin S, Xu J, Yu Y | J Gastrointestin Dis
Aim: To compare the risk of abnormal liver function tests between severe and non-severe patients with coronavirus disease 2019 (COVID-19) by meta-analysis.
CLINICAL CHARACTERISTICS
6/13/20
Wang L, Shen Y, Li M, et al. | J Neurol
Aim: To systematically collect and investigate the clinical manifestations and evidence of neurological involvement in COVID-19.
CLINICAL CHARACTERISTICS
6/12/20
Almufarrij I, Uus K, Munro KJ | Int J Audiol
Aim: To investigate audio-vestibular symptoms associated with coronavirus.
UPDATED
CLINICAL CHARACTERISTICS
6/12/20
Parasa S, Desai M, Chandrasekar VT, et al. | JAMA Netw Open
Aim: To provide a pooled estimate of GI symptoms, liver enzyme levels outside reference ranges, and fecal tests positive for SARS-CoV-2 among patients with COVID-19.
CLINICAL CHARACTERISTICS
6/9/20
Wan S, Li M, Ye Z, et al. | Acad Radiol
Aim: To assess the prevalence of significant computed tomographic(CT) manifestations and describe some notable features based on chest CT images, as well as the main clinical features of patients with coronavirus disease 2019(COVID-19).
CLINICAL CHARACTERISTICS
6/6/20
Romoli M, Jelcic I, Bernard-Valnet R, et al. | Eur J Neurol
Aim: To  review available evidence for reports of neurological signs and symptoms in Coronavirus disease (COVID)-19 patients to identify cases with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection or immune-mediated reaction in the nervous system.
CLINICAL CHARACTERISTICS
6/6/20
Mohamed MFH, A-Shokri S, Yousaf Z, et al. | Am J Trop Med Hyg
Aim: To pool the proportion of various reported lung abnormalities detected by LUS in symptomatic COVID-19 patients. 
CLINICAL CHARACTERISTICS
6/5/20
Pormohammad A, Ghorbani S, Baradaran B, et al. | Rev Med Virol
Aim: To review the evidence on clinical and laboratory characteristics of COVID-19 infected patients.
UPDATED
CLINICAL CHARACTERISTICS
6/3/20
Huang I, Pranata R | J Intensive Care
Aim: To investigate the association of lymphocyte count on admission and the severity of COVID-19.
CLINICAL CHARACTERISTICS
6/1/20
Ojha V, Mani A, Pandey NN, et al. | Eur Radiol
Aim: To evaluate the key imaging manifestations of COVID-19 on chest CT in adult patients by providing a comprehensive review of the published literature.
CLINICAL CHARACTERISTICS
6/1/20
Kunutsor S, Laukkanen J | J Infect
Aim: To review the evidence on clinical characteristics and outcomes of liver injury in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/28/20
Kumar VCS, Mukherjee S, Harne PS, et al. | BMJ Open Gastroenterol
Aim: To perform a systematic review and meta-analysis on the GI symptoms of COVID-19.
CLINICAL CHARACTERISTICS
5/28/20
Keeley P, Buchanan D, Carolan C, et al. | BMJ Palliat Care
Aim: To review the evidence on symptom prevalence and intensity, resistance or susceptibility to symptom control, and mode of death in COVID-19 patients to inform palliative and end-of-life care.
CLINICAL CHARACTERISTICS
5/27/20
Chan VW, Chiu PK, Yee CH, et al. | World J Urol
Aim: To review the evidence on COVID-19 and its potential urological manifestations.
CLINICAL CHARACTERISTICS
5/27/20
Yousefifard M, Zali A, Zarghi A, et al. | Int J Clin Pract
Aim: To evaluate the efficacy and safety of various NSAIDs in viral respiratory infections so that we can reach a conclusion on which NSAID is best choice for COVID-19.
CLINICAL CHARACTERISTICS
5/23/20
Zhang Z, Hou Y, Li D, et al. | Scand J Clin Lab Invest
Aim: To assess laboratory findings in patients with COVID-19.
CLINICAL CHARACTERISTICS
5/22/20
Pranata R, Huang I, Lukito AA, et al. | Postgrad Med J
Aim: To assess the association between N-terminal pro-brain natriuretic peptide (NT-proBNP) and mortality in patients with COVID-19.
CLINICAL CHARACTERISTICS
5/20/20
Liguoro I, Pilotto C, Bonanni M, et al. | Eur J Pediatr
Aim: To systematically review main clinical characteristics and outcomes of SARS-CoV-2 infections in pediatric age.
CLINICAL CHARACTERISTICS
5/19/20
Wang H, Qiu P, Liu J, et al. | Clin Res Hepatol Gastroenterol
Aim: To evaluate the association of liver injury and gastrointestinal symptoms (GIS) with the progression of COVID-19.
CLINICAL CHARACTERISTICS
5/18/20
Mustafa NM, Selim LA | J Clin Virol
Aim: To analyse the disease characterisation in paediatric age group including the possibility of vertical transmission to the neonates.
CLINICAL CHARACTERISTICS
5/18/20
Rafiq D, Batool A, Bazaz MA | Rev Med Virol
Aim: To analyse information on progression of the pandemic in the past 3 months and systematically discusses the characteristics of SARS-CoV-2019 virus including its epidemiologic, pathophysiologic, and clinical manifestations.
CLINICAL CHARACTERISTICS
5/15/20
Sultan S, Altayar O, Siddique SM, et al. | Gastroenterology
Aim: To summarize international data on the Gl and liver manifestations of COVID-19 infection and treatment.
CLINICAL CHARACTERISTICS
5/15/20
Oyelade T, Alqahtani J, Canciani G | Trop Med Infect Dis
Aim: To evaluate the severity and mortality in COVID-19 patients with underlying kidney and liver diseases.
CLINICAL CHARACTERISTICS
5/13/20
Carrillo-Larco RM, Altez-Rodriguez C | Wellcome Open Res
Aim: To determine the frequency of anosmia and dysgeusia in COVID-19 patients, the association of anosmia or dysgeusia with COVID-19 diagnosis, and whether anosmia and dysgeusia are prognostic factors for impaired outcomes among COVID-19 patients.
CLINICAL CHARACTERISTICS
5/13/20
Kermali M, Khalsa RK, Pillai K, et al. | Life Sci
Aim: To evaluate different biomarkers to discover if they are able to predict clinical outcomes and correlate with the severity of COVID-19 disease.
CLINICAL CHARACTERISTICS
5/12/20
Streng A, Hartmann K, Armann J, et al. | Monatsschr Kinderheilkd
Aim: To summarize the current scientific evidence regarding the clinical presentation of COVID-19 in hospitalized children based on available case series from China.
CLINICAL CHARACTERISTICS
5/11/20
Aziz M, Perisetti A, Lee-Smith WM, et al. | Gastroenterology
Aim: To assess the presence of ageusia/dysgeusia among COVID-19 patients.
CLINICAL CHARACTERISTICS
5/9/20
Lechner M, Chandrasekharan D, Jumani K, et al. | Rhinology
Aim: To review the literature of SARS-CoV2 infection/COVID-19 and anosmia to help inform management of anosmia in healthcare works. 
CLINICAL CHARACTERISTICS
5/5/20
Martins-Filho PR, Tavares CSS, Santos VS | Eur J Intern Med
Aim: To comprehensively review studies of clinical and laboratory features of hospitalized patients with COVID-19.
CLINICAL CHARACTERISTICS
4/22/20
Moujaess E, Kourie HR, Ghosn M | Crit Rev Oncol Hematol
Aim: To expose the challenges of cancer management in the era of SARS-CoV-2, the epidemiological, clinical, pathological and radiological characteristics of the disease in cancer patients and its outcomes on this population.
CLINICAL CHARACTERISTICS
4/22/20
Zhu J, Zhong Z, Li H, et al. | J Med Virol
Aim: To systematically review the CT imaging features of COVID-19 in order to provide reference for clinical practice.
CLINICAL CHARACTERISTICS
4/18/20
Panahi L, Amiri M, Pouy S | Arch Acad Emerg Med
Aim: To review articles published on clinical manifestations and characteristics of children and infants with COVID-19.
CLINICAL CHARACTERISTICS
4/17/20
Asadi-Pooya AA, Simani L | J Neruol Sci
Aim: To discuss the evidence on the occurrence of central nervous system (CNS) involvement and neurological manifestations in patients with COVID-19.
CLINICAL CHARACTERISTICS
4/16/20
Zhu J, Ji P, Pang J, et al. | J Med Virol
Aim: To systematically review the clinical characteristics of Coronavirus disease 2019 (COVID?19).
CLINICAL CHARACTERISTICS
4/15/20
Lovato A, de Filippis C | Ear Nose Throat J
Aim: To perform a systematic review of current evidences on clinical presentation of COVID-19, focusing on upper airway symptoms in order to help otolaryngologists identifying suspected cases. 
CLINICAL CHARACTERISTICS
4/15/20
Zhou M, Qi J, Li X, et al. | Br J Haematol
Aim: To analyse the proportion of patients with thrombocytopenia in SARS?CoV, MERS?CoV and 2019?nCoV infections.
CLINICAL CHARACTERISTICS
4/14/20
Fu L, Wang B, Yuan T, et al. | J Infect
Aim: To better inform efforts to treat and control the current outbreak with a comprehensive characterization of COVID-19.
CLINICAL CHARACTERISTICS
4/14/20
Bao C, Liu X, Zhang H, et al. | J Am Coll Radiol
Aim: To provide a summary of evidence on detection of COVID-19 by chest CT and the expected CT imaging manifestations.
CLINICAL CHARACTERISTICS
4/12/20
Etkind SN, Bone AE, Lovell N, et al. | J Pain Symptom Manage
Aim: To synthesise evidence for the role and response of palliative care and hospice teams to viral epi/pandemics, to inform the COVID-19 pandemic response.
CLINICAL CHARACTERISTICS
4/8/20
Zaigham M, Andersson O | Acta Obstet Gynecol Scand
Aim: To summarize the clinical manifestations and maternal and perinatal outcomes of COVID-19 during pregnancy
CLINICAL CHARACTERISTICS
4/7/20
Cheung KS, Hung IF, Chan PP, et al. | Gastroenterology
Aim: To review the published gastrointestinal symptoms and detection of virus in stool, and also summarize data from a cohort of patients with COVID-19 in Hong Kong.
CLINICAL CHARACTERISTICS
4/3/20
Cao Y, Liu X, Xiong L, et al. | J Med Virol
Aim: To explore reliable evidences for the diagnosis and treatment of the COVID-19 by analyzing all the published studies by Chinese scholars on the clinical and imaging features in novel coronavirus pneumonia (NCP) caused by SARS-CoV-2.
CLINICAL CHARACTERISTICS
4/1/20
Seyedi SJ, Shojaeian R, Hiradfar M, et al. | Iran J Pediatr
Aim: To investigate different aspects of COVID-19 infection in pediatrics
CLINICAL CHARACTERISTICS
3/31/20
Bashir N | Lancet
Aim: To collate the available data documenting the radiographic features of COVID-19, and document their prevalence amongst the existing literature
CLINICAL CHARACTERISTICS
3/25/20
Bao C, Liu X, Zhang H, et al. | J Am Coll Radiol
Aim: To provide a more precise estimate of detection of COVID-19 by chest CT and report on the most common imaging findings on chest CT imaging.
CLINICAL CHARACTERISTICS
3/25/20
Mascio DD, Khalil A, Saccone G, et al. | Am J Obs Gynecol
CLINICAL CHARACTERISTICS
3/25/20
Di Mascio D, Khalil A, Saccone G, et al. | Am J Obstet Gynecol
Aim: To report pregnancy and perinatal outcomes of Coronavirus (CoV) spectrum infections, and particularly COVID-19 disease due to SARS-COV-2 infection during pregnancy
CLINICAL CHARACTERISTICS
3/24/20
Emami A, Javanmardi F, Pirbonyeh N, et al. | Arch Acad Emerg Med
Aim: To estimate the prevalence of underlying disorders in hospitalized COVID-19 patients.
CLINICAL CHARACTERISTICS
3/23/20
Ludvigsson JF | Acta Paediatr
Aim: To review the evidence on COVID-19 incidence and disease course in children
CLINICAL CHARACTERISTICS
3/20/20
Vardavas CI, Nikitara K | Tob Induc Dis
Aim: To evaluate the association between smoking and COVID-19 outcomes including the severity of the disease, the need for mechanical ventilation, the need for intensive care unit (ICU) hospitalization and death.
CLINICAL CHARACTERISTICS
3/18/20
Mullins E, Evans D, Viner RM, et al. | Ultrasound Obstet Gynecol
Aim: To guide treatment and prevention in women affected by COVID-19 during pregnancy in the current outbreak.
CLINICAL CHARACTERISTICS
3/14/20
Salehi S, Abedi A, Balakrishnan S, et al. | AJR Am J Roentgenol
Aim: To identify the CT characteristics of this life-threatening and rapidly spreading viral pneumonia, summarize key imaging findings in different stages of the disease, and define the evolution of CT findings associated with disease progression or clinical improvement. We also aim to investigate how CT findings correlate with patients’ age, severity of clinical symptoms, laboratory testing, and disease prognosis.
CLINICAL CHARACTERISTICS
3/13/20
Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, et al. | Travel Med Infect Dis
Aim: To summarize the clinical, laboratory, and image features of COVID-19; to examine the outcome of COVID-19 cases, including risk factors, the proportion of patients requiring ICU and those with fatal outcomes; and to assess the prevalence of comorbidities among COVID-19 confirmed cases.
CLINICAL CHARACTERISTICS
3/12/20
Yang J, Zheng Y, Gou X, et al. | Int J Infect Dis
Aim: To assess the prevalence of comorbidities in the COVID-19 infection patients and the risk of underlying diseases in severe patients compared to non-severe patients.
CLINICAL CHARACTERISTICS
2/26/20
Pang J, Wang MX, Ang IYH, et al. | J Clin Med
Aim: To describe and assess the potential rapid diagnostics, vaccines and therapeutics for 2019-nCoV, based in part on the developments for MERS-CoV and SARS-CoV
CLINICAL CHARACTERISTICS