COVID-19 Evidence Reviews
as of 12/1/20
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Diagnostics
 
= living review
= draft/preprint   |  
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
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11/30/20
Islam N, Salameh JP, Leeflang MMG, et al. | Cochrane Database Syst Rev
Aim: To determine the diagnostic accuracy of chest imaging (computed tomography (CT), X?ray and ultrasound) in people with suspected or confirmed COVID?19.
RECENTLY UPDATED
DIAGNOSTICS
11/25/20
Garg M, Gupta P, Maralakunte M, et al. | Clin Imaging
Aim: To evaluate pooled prevalence, sensitivity, and specificity of chest computed tomography (CT) and radiographic findings for novel coronavirus-2019 (COVID-19) pneumonia.
DIAGNOSTICS
11/9/20
Mekonnen D, Mengist HM, Derbi A, et al.  | Rev Med Virol
Aim: To assess the diagnostic test accuracy (DTA) of severe acute respiratory syndrome coronavirus 2 (SARS?COV?2) serological test methods and the kinetics of antibody positivity. 
DIAGNOSTICS
10/30/20
Ebrahimi M, Malehi AS, Rahim F | Osong Public Health Res Perspect
Aim: To compare coronavirus disease 2019 (COVID-19) laboratory findings, comorbidities, and clinical outcomes in patients from the general population versus medical staff to aid diagnosis of COVID-19 in a more timely, efficient, and accurate way.
DIAGNOSTICS
10/26/20
Comber L, Walsh KA, Jordan K, et al. | Rev Med Virol
Aim: To synthesise the available evidence for detection of SARS?CoV?2 RNA using RT?PCR tested saliva or nasal specimens compared with RT?PCR tested nasopharyngeal specimens.
DIAGNOSTICS
10/26/20
Wang H, Ai J, Loeffelholz MJ, et al. | Emerg Microbes Infect
Aim: To evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals.
DIAGNOSTICS
10/20/20
Hossein H, Ali KM, Hosseini M, et al. | Clin Transl Imaging
Aim: To answer to the question whether CT scan can be used in diagnosis of COVID-19 or not.
DIAGNOSTICS
10/13/20
Aggarwal N, Garg M, Dwarakanathan V, et al. | J Travel Med
Aim: To review the evidence on the diagnostic accuracy of infrared thermal screening via handheld non-contact infrared thermometers and thermal scanners.
DIAGNOSTICS
10/13/20
Roshandel R, Nateqi M, Lak R, et al. | Cell Mol Biol
Aim: To review the evidence on the diagnostic and methodological evaluation of urinary shedding of SARS-CoV-2.
UPDATED
DIAGNOSTICS
10/5/20
Moutchia J, Pokharel P, Kerri A, et al. | PLoS One
Aim: To assess clinical laboratory parameters which may serve as markers or predictors of severe or critical COVID-19.
UPDATED
DIAGNOSTICS
10/5/20
Jarrom D, Elston L, Washington J, et al. | BMJ Evid Based Med
Aim: To identify evidence on: (1) the clinical effectiveness of tests that detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) to inform COVID?19 diagnosis? and (2) the clinical effectiveness of tests that detect the presence of antibodies to the SARS?CoV?2 virus to inform COVID?19 diagnosis.
UPDATED
DIAGNOSTICS
10/2/20
Li WT, Ma J, Shende N, et al. | BMC Med Inform Decis Mak
Aim: To investigate correlations between clinical variables, cluster COVID-19 patients into subtypes, and generate a computational classification model for discriminating between COVID-19 patients and influenza patients based on clinical variables alone.
DIAGNOSTICS
9/21/20
Chen J, See KC | J Med Internet Res
Aim: To review AI applications for COVID-19.
DIAGNOSTICS
9/18/20
Zahra SA, Iddawela S, Pillai K, et al. | Brain Behav
Aim: To investigate the diagnostic value of symptoms of anosmia and dysgeusia for COVID?19.
DIAGNOSTICS
9/18/20
Mojtabavi H, Saghazadeh A, Rezaei N | Eur Cytokine Netw
Aim: To investigate whether the circulating levels of IL-6 is a reliable indicator of disease severity among patients affected with COVID-19.
DIAGNOSTICS
9/15/20
Ricco M, Ranzieri S, Peruzzi S, et al. | Acta Biomed
Aim: To conduct a meta-analysis on the sensitivity and specificity of SARS-CoV-2 viral RNA detection through RT-qPCR based on salivary specimens compared to conventional nasopharyngeal swabs.
DIAGNOSTICS
9/11/20
Sun Z, Zhang N, Li Y, et al. | Quant Imaging Med Surg
Aim: To analyze the currently available studies documenting radiologic findings and aim to clarify the role of CT imaging in the diagnosis of patients with COVID-19.
DIAGNOSTICS
9/11/20
Czumbel LM, Kiss S, Farkas N, et al. | Front Med
Aim: To conduct a meta-analysis on the reliability and consistency of SARS-CoV-2 viral RNA detection in saliva specimens.
UPDATED
DIAGNOSTICS
9/10/20
Liu C, Yang J, Wang W, et al. | Eur J Gastroenterol Hepatol
Aim: To compare liver injury in severe vs. non-severe or dead vs. surviving patients and investigate whether livery injury can help predict clinical severity and mortality in patients with coroanvirus disease 2019.
DIAGNOSTICS
9/9/20
Chauhan N, Soni S, Gupta A, et al. | Expert Rev Mol Diagn
Aim: To review the evidence on diagnostic methods for COVID-19 detection.
DIAGNOSTICS
8/31/20
Almqvist J, Granberg T, Tzortzakakis A, et al. | Ann Clin Transl Neurol
Aim: To optimize diagnostic workup of the current severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) pandemic.
DIAGNOSTICS
8/31/20
Duarte ML, Dos Santos LR, de Souza Contencas AC, et al. | Sao Paulo Med J
Aim: To compare accuracy between RT-PCR and computed tomography (CT) for detecting COVID-19 in the first week of its symptoms during the pandemic.
DIAGNOSTICS
8/26/20
Dinnes J, Deeks JJ, Adriano A et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of point-of-care antigen and molecular-based tests to determine if a person presenting in the community or in primary or secondary care has current SARS-CoV-2 infection
DIAGNOSTICS
8/25/20
van Doorn AS, Meijer B, Frampton CMA, et al. | Aliment Pharmacol Ther
Aim: To critically assess the clinical relevance of testing stool samples and anal swabs and provide an overview of the potential faecal-oral transmission of SARS-CoV-2.
DIAGNOSTICS
8/15/20
Lv H, Chen T, Pan Y, et al. | Ann Transl Med
Aim: To estimate the prevalence and identify the underlying differential diagnostic value of VES.
DIAGNOSTICS
8/14/20
de Moura DTH, McCarty TR, Ribeiro IB, et al. | Clinics (Sao Paulo)
Aim: To perform a structured systematic review and meta-analysis to evaluate the diagnostic characteristics of serological-based COVID-19 testing.
UPDATED
DIAGNOSTICS
7/27/20
Bwire GM, Majigo MV, Nijiro BJ, et al. | J Med Virol
Aim: To profile the positive detection rate from different clinical specimens using PCR to guide the selection of specimens for clinical diagnosis of COVID-19.
UPDATED
DIAGNOSTICS
7/14/20
Boger B, Fachi MM, Vilhena RO, et al. | Am J Infect Control
Aim: To collate the evidence on the accuracy parameters of all available diagnostic methods for detecting SARS-CoV-2.
DIAGNOSTICS
7/14/20
La Marca A, Capuzzo M, Paglia T, et al. | Reprod Biomed Online
Aim: To provide an overview of current diagnostic approaches for SARS-CoV-2 and in particular highlight issues with serological testing, with the objective of providing a clear guide to clinicians on the assays currently available.
DIAGNOSTICS
7/11/20
Albahri OS, Zaidan AA, Albahri AS, et al. | J Infect Public Health
Aim: To review the evidence on artificial intelligence (AI) techniques used in the detection and classification of coronavirus disease 2019 (COVID-19) medical images in terms of evaluation and benchmarking.
DIAGNOSTICS
7/9/20
Shao JM, Ayuso SA, Deerenberg EB, et al. | Colorectal Dis
Aim: To investigate the sensitivity and utility of computed tomography (CT) of the chest in diagnosing active Coronavirus 2019 (COVID?19) infection, and its potential application to the surgical setting.
DIAGNOSTICS
7/7/20
Struyf T, Deeks JJ, Dinnes J et al. | Cochrane Database Syst Rev
Aim: To assess the diagnostic accuracy of signs and symptoms to determine if a person presenting in primary care or to hospital outpatient settings, such as the emergency department or dedicated COVID?19 clinics, has COVID?19 disease or COVID?19 pneumonia.
DIAGNOSTICS
7/3/20
Bastos M, Tavaziva G, Abidi SK, et al. | BMJ
Aim: To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (covid-19).
UPDATED
DIAGNOSTICS
6/23/20
Lv M, Wang M, Yang N, et al. | Ann Transl Med
Aim: To understand the role of CT for the diagnosis and the main imaging manifestations of patients with COVID-19.
UPDATED
DIAGNOSTICS
6/1/20
Adams HJA, Kwee TC, Yakar D, et al. | AJR Am J Roentgenol
Aim: To systematically review and meta-analyze the diagnostic accuracy of chest CT in detecting coronavirus disease (COVID-19).
DIAGNOSTICS
5/24/20
Ricco M, Ferraro P, Gualerzi G, et al. | J Clin Med
Aim: To explore the feasibility of rapid diagnostic tests in the management of the COVID-19 outbreak.
DIAGNOSTICS
5/19/20
Mohammadi A, Esmaeilzadeh E, Li Y, et al. | EBioMedicine
Aim: To review the evidence on respiratory sampling strategies for the detection of SARS-CoV-2 RNA.
DIAGNOSTICS
5/18/20
Xu B, Xing Y, Peng J, et al. | Eur Radiol
Aim: To perform a systematic review and meta-analysis regarding the diagnostic test accuracy of chest CT for detecting coronavirus disease 2019 (COVID-19).
DIAGNOSTICS
5/3/20
Esbin MN, Whitney ON, Chong S, et al. | RNA
Aim: To present a collection of these recent advances in COVID-19 nucleic acid testing, including both peer-reviewed and preprint articles.
DIAGNOSTICS
4/28/20
Bachelet VC | Medwave
Aim: To find and discuss studies on laboratory diagnostic tests and rapid viral diagnosis. 
DIAGNOSTICS
4/24/20
Shormin M, Yusuf MA | Bangladesh J Infect Dis
Aim: To identify the different laboratory tests for detection of SARS Cov2 from Covid19 patients.
DIAGNOSTICS