COVID-19 Evidence Reviews
as of 10/4/22
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Updated Reviews
 
= living review
= draft/preprint   |  
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
latest update
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9/28/22
Sharma A, Vats S, Gupta R, et al. | J Lifestyle Med
Aim: To analyse the overall certainty of evidence regarding the effectiveness of exercise treatment, as well as novel emerging chest rehabilitation approaches during COVID-19 outbreak.
UPDATED
9/26/22
Garcia-Lara RA, Gomez-Urquiza JL, Membrive-Jimenez MJ, et al. | J Pers Med
Aim: To analyse the levels and prevalence of anxiety, distress, and stress during the COVID-19 pandemic in diabetic patients.
UPDATED
MENTAL HEALTH
9/26/22
Albanese A, Sormani MP, Gattorno G, et al. | Mult Scler Relat Disord
Aim: To review the evidence for estimating the severity of COVID-19 events, evaluated as mortality and hospitalization rate, among patients treated with cladribine.
UPDATED
9/26/22
Bellinato F, Fratton Z, Girolomoni G, et al. | Vaccines
Aim: To estimate the pooled incidence of CARs associated with SARS-CoV-2 vaccination in the general adult population.
UPDATED
INFECTION CONTROL
9/26/22
Kovacs EH, Tanczos K, Szabo L, et al. | Biomedicines
Aim: To assess whether higher dose (HD) compared with standard dose (SD) versions of thromboprophylaxis have different effects on clinical outcomes without jeopardizing the safety of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
9/26/22
Kiaei A, Salari N, Boush M, et al. | Life
Aim: To assess the impact and application of artificial intelligence on the identification of suitable drug combinations for treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/26/22
Kang L, Shang W, Gao P, et al. | Vaccines
Aim: To systematically evaluate the immunogenicity and safety of COVID-19 among PLWH.
UPDATED
9/26/22
Ahmed A, Tanveer M, Shrestha S, et al. | Healthcare
Aim: To review the evidence on the interventions and impact of pharmacist-delivered services in managing COVID-19 patients.
UPDATED
9/26/22
Renzi E, Baccolini V, Migliara G, et al. | Vaccines
Aim: To quantify the prevalence estimates of COVID-19 vaccine acceptance with a specific focus on worldwide geographical differences.
UPDATED
INFECTION CONTROL
9/26/22
Wang Z, Chen S, Fang Y | Vaccines
Aim: To systematically search and summarize the evidence from literature reporting parental willingness/hesitancy about the vaccination uptake in their children in the time of COVID-19 (in terms of childhood/routine vaccination, seasonal influenza vaccination, human papillomavirus (HPV) vaccination, and pneumococcal conjugate vaccination (PCV)).
UPDATED
INFECTION CONTROL
9/26/22
Dhungel B, Rahman MS, Rahman MM, et al. | Int J Environ Res Public Health
Aim: To estimate the pooled R0 for early COVID-19 outbreaks and identified the impact of study-related factors such as methods, study location and study period on the estimated R0.
UPDATED
CLINICAL CHARACTERISTICS
9/26/22
Zace D, La Gatta E, Petrella L, et al. | Vaccine
Aim: To summarize and assess available data on the possible impact of COVID-19 vaccines on male and female fertility.
UPDATED
9/26/22
McLean CP, Utpala R, Sharp G | Front Psychol
Aim: To examine the impact of the COVID-19 pandemic on eating disorders and disordered eating behaviors.
UPDATED
MENTAL HEALTH
9/23/22
Moore E, Fadel A, Lane KE, et al. | Nutr Health
Aim: To investigate the effects of consuming a Mediterranean diet on BMI and inflammatory markers of obese/overweight adults (?18 years) at risk of developing severe COVID-19 outcomes.
UPDATED
9/22/22
Witarto BS, Visuddho V, Witarto AP, et al. | PLoS One
Aim: To investigate the effect of online MBIs in improving mental health, mainly depression, anxiety, and stress during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
9/20/22
Alimoradi Z, Lotfi A, Lin CY, et al. | Curr Addict Rep
Aim: To estimate the prevalence of different behavioral addictions (i.e., internet addiction, smartphone addiction, gaming addiction, social media addiction, food addiction, exercise addiction, gambling addiction, and shopping addiction) both overall and separately.
UPDATED
MENTAL HEALTH
9/20/22
Chien TJ, Liu CY, Chang YI, et al. | Front Pharmacol
Aim: To evaluate the efficacy of HM in the treatment of COVID-19 objectively.
UPDATED
CANDIDATE THERAPEUTICS
9/19/22
Cong WH, Saha BK, Tan CK | Prague Med Rep
Aim: To assess the efficacy of routine APP versus standard care in preventing death and invasive mechanical ventilation (IMV) in non-intubated hypoxic COVID-19 patients.
UPDATED
9/19/22
Xie J, He Y, Zheng Y, et al. | Microbiol Res
Aim: To assess the diagnostic accuracy of the rapid antigen test (RAT) compared with RT-PCR (reference standard) for SARS-CoV-2.
UPDATED
DIAGNOSTICS
9/19/22
Yang CW, Chen RD, Zhu QR, et al. | Front Immunol
Aim: To evaluate the effectiveness of UC-MSCs inpatients with COVID-19.
UPDATED
9/19/22
Rahmani K, Shavaleh R, Forouhi M, et al. | Front Public Health
Aim: To evaluate the effectiveness of COVID-19 vaccines, the incidence of SARS-CoV-2 infection, and the hospitalization and mortality due to COVID-19 after vaccination in observational studies.
UPDATED
INFECTION CONTROL
9/19/22
Cong B, Deng S, Wang X, et al. | J Glob Health
Aim: To understand the impact of influenza/RSV co-infection on clinical disease severity among COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
9/19/22
Onakpoya IJ, Heneghan CJ, Spencer EA, | J Hosp Infect
Aim: To assess whether SARS-CoV-2 can be transmitted through fomites, using evidence from viral culture studies.
UPDATED
INFECTION CONTROL
9/12/22
Hasan F, Chiu HY, Salamanca E, et al. | Eur J Dent
Aim: To examine the effects of chlorhexidine (CHX) and povidone-iodine (PVP-I) on the viral load in patients with COVID-19.
UPDATED
9/12/22
Brakspear L, Boules D, Nicholls D, et al. | Nutrients
Aim: To systematically review and appraise the current literature on the impact of COVID-19-related living restrictions on the eating behaviours of children and adolescents.
UPDATED
MENTAL HEALTH
9/9/22
Liang W, Duan Y, Li F, et al. | Ann Behav Med
Aim: To systematically review and meta-analyze available evidence on psychosocial determinants of the general population's practice of three precautionary behaviors, based on the Risk, Attitudes, Norms, Abilities, and Self-regulation (RANAS) framework.
UPDATED
INFECTION CONTROL
9/8/22
Lee JH, Yim J, Park J | Respir Res
Aim: To estimate the pooled prevalence of the pulmonary sequelae of COVID-19, as demonstrated by pulmonary function testing (PFT) and chest computed tomography (CT) performed at least 6 months after initial infection.
UPDATED
CLINICAL CHARACTERISTICS
9/6/22
Toro-Huamanchumo CJ, Hilario-Gomez MM, Pinedo-Castillo L, et al. | New Microbes New Infect
Aim: To evaluate the clinical and epidemiological characteristics in patients with COVID-19 reinfection.
UPDATED
CLINICAL CHARACTERISTICS
9/6/22
Chen Z, Peng Y, Wu X, et al. | Front Public Health
Aim: To identify and assess in-hospital data on comorbidities and complications of COVID-19 that are associated with various levels of disease severity, progression, and mortality in China during centralized isolation and hospitalization.
UPDATED
CLINICAL CHARACTERISTICS
9/6/22
Terry E, Cartledge S, Damery S, et al. | BMC Public Health
Aim: To identify factors associated with public intention to receive COVID-19 vaccines until February 2021 to provide accessible data to policymakers to inform framing and targeting of messages designed to optimise vaccine uptake.
UPDATED
INFECTION CONTROL
9/6/22
O'Byrne L, Webster KE, MacKeith S, et al. | Cochrane Database Syst Rev
Aim: To assess the effects (benefits and harms) of interventions that have been used, or proposed, to treat persisting olfactory dysfunction due to COVID-19 infection.
UPDATED
CANDIDATE THERAPEUTICS
9/6/22
Shrestha AB, Aryal M, Magar JR, et al. | Ann Med Surg
Aim: To observe the current scenario of self-medication regarding the management or prevention of COVID-19. 
UPDATED
9/2/22
Zinellu A, Mangoni AA | Expert Rev Clin Immunol
Aim: To review the evidence on the association between the neutrophil, lymphocyte, and platelet count, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), and COVID-19 progression and mortality.
UPDATED
CLINICAL CHARACTERISTICS
9/2/22
Wu PC, Huang IH, Wang CW, et al. | Am J Clin Dermatol
Aim: To investigate the demographics, clinical variables, and outcomes associated with psoriasis following COVID-19 vaccination.
UPDATED
INFECTION CONTROL
9/1/22
Ghasemi H, Darvishi N, Salari N, et al. | Trop Med Health
Aim: To evaluate the prevalence of polypharmacy among the COVID-19 patients, and the side effects, by systematic review and meta-analysis.
UPDATED
8/30/22
Elshenawy RA, Umaru N, Alharbi AB, et al. | Research Square
Aim: To investigate the AMS intervention Pre-pandemic (PP) and During-the-pandemic (DP) from the literature.
UPDATED
8/30/22
Tang HJ, Weng TS, Chen YH, et al. | J Microbiol Immunol Infect
Aim: To investigate the clinical efficacy and safety of oral Janus kinase inhibitors (JAKis) in the treatment of hospitalized patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/29/22
Nagarajan R, Krishnamoorthy Y, Rajaa S, et al. | Prev Chronic Dis
Aim: To determine the association of chronic liver disease (CLD), a comorbid condition, with severity of disease and death among COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/29/22
Islam MA, Cavestro C, Alam SS, et al. | Cells
Aim: To systematically evaluate the characteristics (clinical, neuro-radiological aspects, and laboratory features) and outcomes of encephalitis in COVID-19 patients, as well as the possible causative mechanisms of CNS damage.
UPDATED
CLINICAL CHARACTERISTICS
8/29/22
Li M, Wang X, Feng J, et al. | Vaccines
Aim: To assess the incidence of myocarditis and pericarditis after COVID-19 vaccination in children and adolescents.
UPDATED
8/29/22
Di Spirito F, Amato A, Di Palo MP, et al. | Int J Environ Res Public Health
Aim: To assess current data on cases diagnosed with oral lesions among adult subjects (?18 years old) who had received at least one dose of the World Health Organization (WHO) Emergency Use Listing approved [10] and European Medicines Agency (EMA) authorized [11] anti-SARS-CoV-2 vaccines, classify oral mucosal manifestations based on primary oral lesions, and describe their macroscopic and microscopic features.
UPDATED
8/29/22
Xu X, Feng Y, Jia Y, et al. | Thromb Res
Aim: To review the evidence on the relationship between both VWF and its cleaving protease ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13) with the prognosis of COVID-19.
UPDATED
8/29/22
Scarpelli S, Zagaria A, Ratti PL, et al. | Sleep Med
Aim: To provide an update on sleep quality in different world areas and better characterize subjective sleep alterations during the COVID-19 pandemic.
UPDATED
8/29/22
Lai CC, Wang YH, Chen KH, et al. | Viruses
Aim: To compare the clinical efficacy and safety of anti-viral agents for the prevention of disease progression among non-hospitalized patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/29/22
Parthasarathi A, Padukudru S, Arunachal S, et al. | Vaccines
Aim: To assess the relationship between on-admission NLR values and COVID-19-related disease severity and mortality outcomes.
UPDATED
CLINICAL CHARACTERISTICS
8/26/22
Stefanou MI, Palaiodimou L, Aguiar de Sousa D, et al. | Neurology
Aim: To provide the prevalence of arterial AIS following exposure to vectorbased and mRNA SARS-CoV-2 vaccines.
UPDATED
8/26/22
Ahmadi Marzaleh M, Peyravi M, Azhdari N, et al. | Disaster Med Public Health Prep
Aim: To evaluate the investigations that utilized telerehabilitation to assist elderly people during the COVID-19 pandemic.
UPDATED
8/26/22
Zavalaga-Zegarra HJ, Palomino-Gutierrez JJ, Ulloque-Badaracco JR, et al. | Trop Med Infect Dis
Aim: To investigate the CAR values with respect to the severity and mortality of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/26/22
Greer N, Bart B, Billington CJ, et al. | BMJ Open
Aim: To examine major organ damage postdischarge among adults hospitalised for COVID-19 versus non-COVID-19 controls.
UPDATED
VA ESP
LONG COVID
8/26/22
Ulloque-Badaracco JR, Alarcon-Braga EA, Hernandez-Bustamante EA, et al. | Trop Med Infect Dis
Aim: To evaluate the association of fibrinogen-to-albumin ratio and blood urea nitrogen-to-albumin ratio with the severity and mortality of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/25/22
Duo H, Li Y, Sun Y, et al. | Thromb J
Aim: To review the evidence on the efficacy and safety of therapeutic anticoagulation (T-AC) versus a lower dose, prophylaxis anticoagulation (P-AC) in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
8/25/22
Richter SA, Ferraz-Rodrigues C, Schilling LB, et al. | J Sleep Res
Aim: To review the evidence on the potential influence of the COVID-19 pandemic on sleep quality in children and adolescents. 
UPDATED
8/25/22
Nagraj S, Varrias D, Hernandez Romero G, et al. | Stroke
Aim: To provide an accurate and reliable estimate of stroke incidence among patients with COVID-19 by assessing strokes reported as outcome or adverse events in RCTs in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/24/22
Jia LL, Zhao JX, Pan NN, et al. | Eur J Radiol Open
Aim: To provide an overview of radiomics studies identifying COVID-19 from other pneumonias and evaluate the efficacy of prediction models.
UPDATED
DIAGNOSTICS
8/24/22
Ezzatvar Y, Ramírez-Vélez R, Izquierdo M, et al. | Br J Sports Med
Aim: To quantify the association between physical activity and risk of SARS-CoV-2 infection, COVID-19-associated hospitalisation, severe illness and death due to COVID-19 in adults.
UPDATED
8/24/22
Wynants L, Van Calster B, Bonten MMJ | BMJ
Aim: To review and critically appraise published and preprint reports of models that aim to predict either (i) presence of existing COVID-19 infection, or (ii) future complications in individuals already diagnosed with COVID-19
UPDATED
DIAGNOSTICS
8/24/22
Almadhoon HW, Hamdallah A, Elsayed SM, et al. | Sci Rep
Aim: To review the evidence on the link between influenza vaccination and the severity of COVID-19 infection.
UPDATED
8/23/22
Khalid Ahmed S, Gamal Mohamed M, Abdulrahman Essa R, et al. | Int J Cardiol Vasc Heart
Aim: To provide a comprehensive overview of takotsubo cardiomyopathy (TCM) associated with COVID-19 vaccines.
UPDATED
CLINICAL CHARACTERISTICS
8/23/22
Zangani C, Ostinelli EG, Smith KA, et al. | JMIR Mental Health
Aim: To systematically review the global research literature on how mental health service provision adapted during the first year of the pandemic.
UPDATED
MENTAL HEALTH
8/23/22
Vitória BA, Ribeiro MT, Carvalho VS | Front Psychol
Aim: To synthesize how COVID-19 has impacted the work-family interface.
UPDATED
8/22/22
Bhattacharya O, Siddiquea BN, Shetty A, et al. | BMJ Open
Aim: To estimate the vaccines' acceptance level and to find the factors influencing pregnant women's vaccination decisions.
UPDATED
INFECTION CONTROL
8/22/22
Tahsini Tekantapeh S, Ghojazadeh M, Ghamari AA, et al. | Expert Rev Respir Med
Aim: To review the evidence on therapeutic and anti-inflammatory effects of baricitinib on mortality, ICU transfer, clinical improvement, and CRS-related laboratory parameters of hospitalized patients with moderate to severe COVID-19 pneumonia.
UPDATED
CANDIDATE THERAPEUTICS
8/18/22
Siddiq S, Ahmed S, Akram I | Public Health
Aim: To evaluate the differences in clinical outcomes of COVID-19 infection between ethnic minorities and the White ethnic group in the UK.
UPDATED
8/18/22
Patel C, Parmar K, Patel D, et al. | Rev Med Virol
Aim: To investigate the effect of corticosteroids on mortality in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/18/22
Ali SS, Mumtaz A, Qamar MA, et al. | Ann Med Surg
Aim: To highlight Parkinsonism as a post-COVID-19 sequela and helps us understand a possible link between the two.
UPDATED
LONG COVID
8/18/22
Ge C, Du K, Luo M, et al. | Exp Hematol Oncol
Aim: To evaluate the serologic response and safety of COVID-19 vaccines in these population.
UPDATED
INFECTION CONTROL
8/16/22
Zhiyu Y, Wentian L, Ruizi Z | J Affect Disord
Aim: To understand the commonly used psychosocial interventions during the COVID-19 pandemic and the effectiveness of the interventions.
UPDATED
MENTAL HEALTH
8/16/22
Qian Z, Zhang Z, Ma H, et al. | Front Immunol
Aim: To assess whether convalescent plasma therapy could offer survival advantages for patients with novel coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
8/15/22
Kauhanen L, Wan Mohd Yunus WMA, Lempinen L, et al. | Eur Child Adolesc Psychiatry
Aim: To compare the mental health of children and young people aged 0–24, before and during the COVID-19 pandemic, and identify any changes.
UPDATED
MENTAL HEALTH
8/15/22
Dobrijevic Z, Robajac D, Gligorijevic N, et al. | EXCLI J
Aim: To investigate the association of VDR and IFITM3 polymorphisms with COVID-19 severity.
UPDATED
CLINICAL CHARACTERISTICS
8/12/22
Kabia AU, Li P, Jin Z, et al. | J Hypertens
Aim: To review the evidence on the effects of hypertension and age as well as the use of ACEI/ARB treatment on the outcomes of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
8/11/22
Che BW, Chen P, Yu Y, et al. | Asian J Androl
Aim: To explore whether mild/asymptomatic COVID-19 affects semen quality and sex-related hormone levels.
UPDATED
CLINICAL CHARACTERISTICS
8/10/22
Kim DK, Park JJ, Yang WJ, et al. | J Korean Med Sci
Aim: To characterize the relationship between ADT and the severity of COVID-19 in patients with prostate cancer.
UPDATED
CLINICAL CHARACTERISTICS
8/10/22
Mishra P, Parveen R, Bajpai R, et al. | J Prev Med Public Health
Aim: To investigate the association of lower levels of vitamin D and comorbidities with the risk of COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
8/9/22
Ding S, Deng S, Zhang Y, et al. | Front Public Health
Aim: To explore front-line nurses' experiences and needs during the COVID-19 pandemic through a qualitative meta-synthesis.
UPDATED
8/9/22
Yang Z, Wang X, Zhang S, et al. | Front Public Health
Aim: To compare myopia progression in children before the COVID-19 pandemic and during COVID-19 pandemic home quarantine and at the same time explore the risk factors of myopia progression.
UPDATED
8/9/22
Whear R, Bethel A, Abbott R, et al. | J Clin Epidemiol
Aim: To suggest possible approaches to combatting the impact of the COVID-19 infodemic in-order to prevent research waste in future health emergencies and in everyday research and practice.
UPDATED
8/8/22
Alves EAS, Salazar TCDN, Silvino VO, et al. | Nutr Clin Pract
Aim: To evaluate the association between phase angle and adverse clinical outcomes in hospitalized patients with coronavirus disease-2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
8/8/22
Georgakopoulou VE, Gkoufa A, Garmpis N, et al. | Ann Saudi Med
Aim: To review and analyze all reported cases of COVID-19 associated acute pancreatitis, reporting the demographics, clinical characteristics, laboratory and imaging findings, comorbidities and outcomes.
UPDATED
CLINICAL CHARACTERISTICS
8/5/22
Meshram HS, Kute V, Rane H, et al. | Transpl Infect Dis
Aim: To analyze the humoral and cellular response to standard and booster (additional doses) COVID-19 vaccination in solid organ transplantation (SOT) and the risk factors involved for an impaired response.
UPDATED
8/3/22
Aryana IGPS, Daniella D, Paulus IB, et al. | Ann Geriatr Med Res
Aim: To examine the effect of CP in older adults with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/3/22
Turki A, Abbas KS, Makram AM, et al. | Acta Neurol Belg
Aim: To systematically review the clinical picture, laboratory/imaging findings, treatment options, and prognostic factors of FNP in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/3/22
Meyer D, Slone SE, Ogungbe O, et al. | AIDS Behav
Aim: To assess the impacts of the pandemic on service engagement, treatment adherence, and viral suppression.
UPDATED
8/2/22
Luo X, Lv M, Zhang X, et al. | J Evid Based Med
Aim: To present a comprehensive picture of the clinical symptoms of COVID-19 using an evidence map.
UPDATED
CLINICAL CHARACTERISTICS
8/2/22
Cevik A, Onat Koroglu C, Karacam Z, et al. | Clin Nurs Res
Aim: To determine the effects of the Covid-19 pandemic on the prevalence of insomnia, anxiety, and depression symptoms during pregnancy.
UPDATED
MENTAL HEALTH
8/1/22
Chou OHI, Mui J, Chung CT, et al. | Clin Res Cardiol
Aim: To investigate the rates of carditis in children and adolescents receiving COVID-19 vaccines.
UPDATED
CLINICAL CHARACTERISTICS
7/29/22
Sah SK, Shariff A, Pathakamuri N, et al. | PLoS One
Aim: To find the prevalence of fungal secondary infections among COVID-19 patients and patient outcomes in terms of recovery or all-cause mortality following antifungal therapy (AFT) in such patients.
UPDATED
CLINICAL CHARACTERISTICS
7/29/22
Bailly M, Pélissier L, Coudeyre E, et al. | Int J Environ Res Public Health
Aim: To systematically review the effects of physical activity programs in the recovery of post-COVID-19 patients. 
UPDATED
LONG COVID
7/28/22
Hung KC, Huang YT, Chang YJ, et al. | Diagnostics
Aim: To examine the association of the F/A ratio with prognostic outcomes among patients contracting COVID-19.
UPDATED
DIAGNOSTICS
7/28/22
Hung KC, Ko CC, Wang LK, et al. | Diagnostics
Aim: To evaluate the prognostic value of PNI for predicting the severity and mortality in patients diagnosed with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/28/22
Arias M, Oliveros H, Lechtig S, et al. | Pharmaceuticals
Aim: To reevaluate the available evidence of the use of biologics as treatment candidates for the treatment of severe and advanced COVID-19 disease
UPDATED
CANDIDATE THERAPEUTICS
7/28/22
Komariah M, Amirah S, Faisal EG, et al. | Healthcare
Aim: To evaluate the efficacy of iCBT for depression and anxiety among the global population during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
7/28/22
Spencer N, Markham W, Johnson S, et al. | Vaccines
Aim: To address the existing gap in the body of evidence and assess the impact of the COVID-19 pandemic on inequities in routine childhood vaccination coverage.
UPDATED
INFECTION CONTROL
7/27/22
Gaigher JM, Lacerda IB, Dourado MCN | Front Psychiatry
Aim: To better understand the impacts of the COVID-19 pandemic on people with dementia and on their caregivers' mental health.
UPDATED
MENTAL HEALTH
7/27/22
Kulkarni D, Nundy M, McSwiggan E, et al. | J Glob Health
Aim: To explore the association between alcohol consumption in social gatherings and compliance with COVID-19 public health measures.
UPDATED
INFECTION CONTROL
7/25/22
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on post-acute sequelae of COVID-19 infection.
UPDATED
7/19/22
Biagianti B, Di Liberto A, Nicolo Edoardo A, et al. | Front Aging Neurosci
Aim: To provide a critical narrative of neuropsychological (NPs) deficits commonly observed after SARS-CoV-2 infection and the tests most suited for detecting such cognitive sequelae depending on illness severity.
UPDATED
MENTAL HEALTH
7/19/22
Kariya A, Krutsri C, Singhatas P, et al. | Int J Surg Open
Aim: To analyze the rate of complicated appendicitis before and during the COVID-19 pandemic.
UPDATED
7/19/22
Mohammadi S, Gouravani M, Salehi MA, et al. | Neuroradiology
Aim: To aggregate the results of the studies which reported imaging of the olfactory system of patients with COVID-19 versus controls.
UPDATED
CLINICAL CHARACTERISTICS
7/19/22
Hessami K, Sayegh N, Abdolmaleki AS, et al. | J Obstet Gynaecol Res
Aim: To systematically review and summarize the available literature regarding the women's sexual function during COVID-19 pandemic and compare it to pre-pandemic period.
UPDATED
7/18/22
Lan SH, Hsu CK, Lai CC, et al. | Ann Med
Aim: To assess the usefulness of colchicine in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
7/18/22
Xue C, Liu Z, Xiang H, et al. | Altern Health Ther Med
Aim: To determine the efficacy of interferon (IFN)-based therapy for coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
7/18/22
Cénat JM, Farahi SMMM, Dalexis RD, et al. | J Affect Disord
Aim: To assess the global evolution of mental health problems during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
7/18/22
Fang Y, Ji B, Liu Y, et al. | Sci Rep
Aim: To identify the incidence of psychological stress reactions in student populations following a global outbreak and the associated influencing factors.
UPDATED
MENTAL HEALTH
7/14/22
Siemieniuk RAC, Bartoszko JJ, Ge L, et al. | BMJ
Aim: To compare the effects of treatments for coronavirus disease 2019 (covid-19).
UPDATED
CANDIDATE THERAPEUTICS
7/14/22
Arayici ME, Kipcak N, Kayacik U, et al. | J Cancer Res Clin Oncol
Aim: To determine both the incidence and ICU (Intensive Care Unit) admission rates and mortality in SARS-CoV-2 infected cancer patients.
UPDATED
CLINICAL CHARACTERISTICS
7/14/22
Baradaran HR, Dehghanbanadaki H, Moradpour F, et al. | Expert Rev Vaccines
Aim: To investigate the pooled effect of COVID-19 mRNA vaccination against SARS-CoV-2 infection and its clinical outcomes.
UPDATED
7/13/22
Saragih ID, Tarihoran DETAU, Rasool A, et al. | J Nurs Scholarsh
Aim: To update estimates of the prevalence of stigmatization and violence against healthcare workers during the pandemic.
UPDATED
7/13/22
Bitar AN, Sulaiman SAS | Curr Med Res Opin
Aim: To evaluate the evidence from clinical trials on the effect of colchicine and corticosteroids against COVID-19.
UPDATED
7/13/22
Tugasworo D, Kurnianto A, Retnaningsih, et al. | Egypt J Neurol Psychiatr Neurosurg
Aim: To assess and conclude the research-based study systematically to analyze the relationship of MG and COVID-19.
UPDATED
7/12/22
Nazari T, Sadeghi F, Izadi A, et al. | PLoS One
Aim: To summarize the studies that have reported CAFIs in Iran.
UPDATED
7/12/22
Neville RD, Lakes KD, Hopkins WG, et al. | JAMA Pediatr
Aim: To estimate whether changes in physical activity differed between participant-level, contextual, and methodological moderators during the COVID-19 pandemic.
UPDATED
7/12/22
Sawadogo W, Tsegaye M, Gizaw A, et al. | BMJ Nutr Prev Health
Aim: To quantify the association between overweight or obesity and COVID-19-related hospitalisations (including hospital admission, intensive care unit (ICU) admission, invasive mechanical ventilation (IMV)) and death, and to assess the magnitude of the association and the potential dose–response relationships.
UPDATED
CLINICAL CHARACTERISTICS
7/7/22
Dieter C, Brondani LA, Leitao CB, et al. | PLoS One
Aim: To identify genetic polymorphisms that are likely to contribute to COVID-19 pathogenesis.
UPDATED
CLINICAL CHARACTERISTICS
7/7/22
D'Ecclesiis O, Gavioli C, Martinoli C, et al. | PLoS One
Aim: To assess the evidence on SARS-CoV2 infection and Covid-19 in relation to deficiency and supplementation of vitamin D.
UPDATED
CLINICAL CHARACTERISTICS
7/6/22
Malinga DM, Laher AE, McDowall J, et al. | Curr Urol
Aim: To explore the potential relationship between priapism and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/6/22
Araújo ST, Araújo CT, Silva E Castro R, et al. | Curr Med Chem
Aim: To investigate potential neuroimaging markers of early diagnosis and prognosis of neurologic manifestations in COVID-19.
UPDATED
DIAGNOSTICS
7/6/22
Halabchi F, Selk-Ghaffari M, Tazesh B, et al. | Sport Sci Health
Aim: To investigate the role of exercise rehabilitation programs, either in acute or post-acute phase, on physical and psychological outcomes among COVID-19 patients.
UPDATED
7/5/22
Sun XH, Zhang S, Yang Z, et al. | Chin J Integr Med
Aim: To evaluate the efficacy and safety of LHQW for COVID-19 by conducting a systematic review with meta-analysis.
UPDATED
CANDIDATE THERAPEUTICS
7/5/22
Zong K, Peng D, Yang H, et al. | Front Immunol
Aim: To determine the factors that contribute to poor antibody response in organ transplant recipients after receiving the 2-dose severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine.
UPDATED
CLINICAL CHARACTERISTICS
7/1/22
Almeda N, Gomez-Gomez I | Front Psychiatry
Aim: To analyse the changes in smoking consumption during the COVID-19 pandemic through longitudinal studies. 
UPDATED
6/24/22
Roshdy A, Elsayed AS, Saleh AS | J Intensive Care Med
Aim: To explore the evidence surrounding the use of Airway Pressure Release Ventilation (APRV) in patients with coronavirus disease 2019 (COVID-19).
UPDATED
6/23/22
Ji Z, Hu H, Qiang X, et al. | Am J Chin Med
Aim: To compare the efficacy of different traditional Chinese medicine (TCM) therapies for the treatment of coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
6/22/22
Wang Q, Guo S, Wei X, et al. | BMJ Open
Aim: To systematically review the evidence on this topic and provide comprehensive information to guide the control and treatment of TB-COVID coinfection.
UPDATED
INFECTION CONTROL
6/21/22
Qin J, Wang G, Han D | Int J Infect Dis
Aim: To determine the efficacy of therapeutic plasma exchange (TPE) on mortality in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/21/22
Khanal R, Raj Bhattarai S, Basnet K, et al. | Interdiscip Perspect Infect Dis
Aim: To review the evidence on the cardiac implications of COVID-19, both in terms of cardiac factors predisposing to the disease and cardiac complications of the disease.
UPDATED
CLINICAL CHARACTERISTICS
6/21/22
Levy M, Lestrade V, Said C, et al. | Front Pediatr
Aim: To synthesize knowledge describing the impact of social distancing measures (SDM) during the first wave of the COVID-19 pandemic on acute illness in children.
UPDATED
INFECTION CONTROL
6/21/22
Alemayehu A, Demissie A, Yusuf M, et al. | Health Serv Res Manag Epidemiol
Aim: To pool the prevalence of COVID-19 vaccine acceptance and identify its determinants in East Africa.
UPDATED
INFECTION CONTROL
6/21/22
Tan RSJ, Ng KT, Xin CE, et al. | J Cardiothorac Vasc Anesth
Aim: To evaluate the use of high-dose versus low- dose corticosteroids on the mortality rate of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
6/21/22
Sadeghi S, Kalantari Y, Shokri S, et al. | J Clin Virol
Aim: To collect all the data about immunogenicity, efficacy, and safety of available COVID-19 vaccines to guide health care workers and families on vaccinating the younger population (2 – 21 years old).
UPDATED
INFECTION CONTROL
6/21/22
Li L, Wang F, Shui X, et al. | PLoS One
Aim: To evaluate the pooled estimated level of knowledge, attitudes, and practices (KAP) about COVID-19 among college students in China.
UPDATED
6/21/22
Lee JX, Chieng WK, Abdul Jalal MI, et al. | Front Med
Aim: To determine the role of serum ferritin in predicting outcomes of COVID-19 infection among patients with SCD.
UPDATED
CLINICAL CHARACTERISTICS
6/21/22
Antonini M, Hinwood M, Paolucci F, et al. | World J Surg
Aim: To investigate changes in the epidemiology of major trauma presentations during the implementation of movement restriction measures to manage the first wave of the SARS-CoV-2 (COVID-19) pandemic.
UPDATED
6/16/22
Seid AA, Woday Tadesse A, Hasen AA | BMJ Open
Aim: To determine the severity and mortality of COVID-19 among people with different types of disabilities.
UPDATED
CLINICAL CHARACTERISTICS
6/14/22
Kramer A, Prinz C, Fichtner F, et al. | Cochrane Database Syst Rev
Aim: To assess the effects of systemic JAK inhibitors plus standard of care compared to standard of care alone (plus/minus placebo) on clinical outcomes in individuals (outpatient or in-hospital) with any severity of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/14/22
Battaglini D, Premraj L, Huth S, et al. | J Neurosurg Anesthesiol
Aim: To investigate the use of noninvasive multimodal neuromonitoring in critically ill adult patients with COVID-19 infection.
UPDATED
6/13/22
Alarcon-Braga EA, Hernandez-Bustamante EA, Salazar-Valdivia FE, et al. | Travel Med Infect Dis
Aim: To estimate the prevalence of the intention to vaccinate against COVID-19 in LAC, and to explore how it varies between different age groups.
UPDATED
INFECTION CONTROL
6/13/22
Kirby A, Drummond FJ, Lawlor A, et al. | Support Care Cancer
Aim: To examine the social, psychological, and economic impacts of COVID-19 on cancer patients.
UPDATED
6/13/22
Ma Y, Deng J, Liu Q, et al. | Int J Environ Res Public Health
Aim: To evaluate the long-term consequences of coronavirus disease 2019 (COVID-19) at 6 months and above.
UPDATED
CLINICAL CHARACTERISTICS
6/13/22
Hernández-Díaz Y, Genis-Mendoza AD, Ramos-Méndez MÁ, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the mental health effects of the COVID-19 pandemic on the general population in Mexico.
UPDATED
MENTAL HEALTH
6/13/22
Krumbein H, Kümmel LS, Fragkou PC, et al. | Rev Med Virol
Aim: To critically assess the published literature related to community-acquired viral co-infections and COVID-19 and to evaluate the prevalence, most identified co-pathogens, and relevant risk factors.
UPDATED
CLINICAL CHARACTERISTICS
6/13/22
Banchelli F, Negro P, Guido M, et al. | J Clin Med
Aim: To investigate the role that ABO blood groups play in susceptibility to SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
6/10/22
Bhattarai A, Dhakal G, Shah S, et al. | Interdiscip Perspect Infect Dis
Aim: To review the evidence on the effect of preexisting asthma on the risk of ICU admission, intubation, and death from COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/10/22
Aamir Waheed M, Rashid K, Rajab T, et al.  | Saudi Med J
Aim: To compare the mortality associated with the intensity of anticoagulation in patients admitted with covid-19.
UPDATED
CLINICAL CHARACTERISTICS
6/9/22
Carle C, Hughes S, Freeman V, et al. | J Cancer Policy
Aim: To review the evidence on the risk for people with cancer to be infected with SARS-CoV-2 compared to people without cancer.
UPDATED
INFECTION CONTROL
6/8/22
Zeng N, Zhao YM, Yan W, et al.  | Mol Psychiatry
Aim: To review the evidence on COVID-19 survivors’ health consequences and sequelae for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/8/22
Fei Z, Chen Z, Du X, et al. | Transfus Med Hemother
Aim: To determine the safety and efficacy of IVIG and CP for COVID-19 and the different treatment effects between these two therapeutics to provide references for treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/7/22
Aryana IGPS, Setiati S, Paulus IB, et al. | J Nutr Metab
Aim: To investigate physical training on muscle health and QOL in patients with COVID-19.
UPDATED
6/7/22
Shafiee A, Teymouri Athar MM, Nassar M, et al. | Diabetes Metab Syndr
Aim: To evaluate the current evidence available to investigate clinical outcomes between patients with type 1 and type 2 diabetes.
UPDATED
CLINICAL CHARACTERISTICS
6/7/22
Salari N, Vepa A, Daneshkhah A, et al. | Public Health
Aim: To assess to what extent COVID-19 clinical trials have considered the impact of race and ethnicity on COVID-19 vaccine safety and efficacy.
UPDATED
INFECTION CONTROL
6/7/22
Ahmed SK, Mohamed MG, Essa RA, et al. | Diabetes Metab Syndr
Aim: To examine the evidence on myocarditis following COVID-19 vaccination, focusing on patient and disease characteristics, as well as investigation and clinical outcome.
UPDATED
INFECTION CONTROL
6/7/22
Delanerolle G, Zeng Y, Shi JQ, et al. | World J Psychiatry
Aim: To identify and report: (1) MH conditions commonly observed across all 3 pandemics; (2) Impact of MH outcomes across HCPs, patients and the general public associated with all 3 pandemics; and (3) The prevalence of the MH impact and clinical epidemiological significance.
UPDATED
MENTAL HEALTH
6/7/22
Zhi H, Ji X, Zhao Z, et al. | EClinicalMedicine
Aim: To review the evidence on the potential risk factors for impaired diffusing capacity for carbon monoxide (DLCO) in convalescent COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
6/6/22
Mose A, Wasie A, Shitu S, et al.  | PLoS One
Aim: To estimate the pooled prevalence of COVID-19 vaccine acceptance and its determinants in Ethiopia.
UPDATED
INFECTION CONTROL
6/6/22
Bello UM, Kannan P, Chutiyami M, et al. | Front Public Health
Aim: To review the evidence on the prevalence of anxiety and depression among the general populace in Africa during the COVID-19 pandemic and examine associated risk factors.
UPDATED
MENTAL HEALTH
6/6/22
Subramaniam A, Lim ZJ, Ponnapa Reddy M, et al. | ANZ J Surg
Aim: To investigate the occurrence of SARS-CoV-2 transmission from patients to healthcare workers (HCWs) when tracheostomies are performed.
UPDATED
INFECTION CONTROL
6/2/22
Shin JI, Kim SE, Lee MH, et al. | Eur Rev Med Pharmacol Sci
Aim: To assess the susceptibility to and clinical outcomes of COVID-19 in autoimmune inflammatory rheumatic disease (AIRD) and following AIRD drug use.
UPDATED
CLINICAL CHARACTERISTICS
6/2/22
Okita Y, Morita T, Kumanogoh A | Inflamm Regen
Aim: To review the evidence on the duration of SARS-CoV-2 RNA positivity from several parts of the obdy and clinical characteristics affecting it.
UPDATED
CLINICAL CHARACTERISTICS
6/2/22
Fragkou PC, Palaiodimou L, Stefanou MI, et al. | Ther Adv Neurol Disord
Aim: To review the effects of different dosing regimens of low molecular weight heparin and/or fondaparinux (LMWH/F) on mortality risk as well as the risk of arterial/venous thrombotic events and hemorrhagic complications in confirmed COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
6/2/22
Fakhruddin KS, Samaranayake LP, Buranawat B, et al. | PLoS One
Aim: To review the prevalence, the likely aetiopathogenesis, and the management of oro-facial mucocutaneous manifestations of Coronavirus Disease-2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2).
UPDATED
CLINICAL CHARACTERISTICS
6/2/22
Zhou Y, Ge YT, Yang XX, et al. | Front Public Health
Aim: To determine the prevalence of PE elevation, and the relationship between elevated PE and prognosis in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
6/2/22
Huntley CC, Patel K, Bil Bushra SE, et al. | ERJ Open Res
Aim: To describe and compare the longitudinal pulmonary function and computed tomography (CT) features of patients recovering from SARS, MERS and COVID-19 during follow-up.
UPDATED
CLINICAL CHARACTERISTICS
6/2/22
Hawco S, Rolnik DL, Woolner A, et al. | Eur J Obstet Gynecol Reprod Biol
Aim: To review the evidence on the relationship between SARS-CoV-2 mitigation measures and perinatal outcomes, with extensive subgroup analysis. 
UPDATED
CLINICAL CHARACTERISTICS
6/1/22
Allotey J, Stallings E, Bonet M, et al. | BMJ
Aim: To determine the clinical manifestations, risk factors, and maternal and perinatal outcomes in pregnant and recently pregnant women with suspected or confirmed coronavirus disease 2019 (covid-19).
UPDATED
CLINICAL CHARACTERISTICS
5/31/22
Lemes IR, Smaira FI, Ribeiro WJD, et al. | Br J Sports Med
Aim: To describe acute/postacute COVID-19 presentations in athletes.
UPDATED
CLINICAL CHARACTERISTICS
5/31/22
Lee ARYB, Wong SY, Tay SH | Vaccines
Aim: To study seroconversion rates and antibody levels post-vaccination in IMID patients.
UPDATED
INFECTION CONTROL
5/31/22
Fernández-Lázaro D, Ortega CD, Sánchez-Serrano N, et al. | Pharmaceutics
Aim: To systematically analyze the evidence of the effect and safety of treatment with CP therapy using randomized controlled trials (RCTs) to confirm the usefulness of this intervention in hospitalized patients with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
5/31/22
Hosseini B, El Abd A, Ducharme FM | Nutrients
Aim: To evaluate the impact of vitamin D supplementation on COVID-19 related outcomes.
UPDATED
CANDIDATE THERAPEUTICS
5/31/22
Jia Q, Qu Y, Sun H, et al. | Front Psychol
Aim: To assess the pooled prevalence of depression and anxiety among medical students worldwide.
UPDATED
MENTAL HEALTH
5/31/22
Buitrago-Garcia D, Ipekci AM, Heron L, et al. | PLoS Med
Aim: To review the evidence on asymptomatic SARS-CoV-2 transmission.
UPDATED
CLINICAL CHARACTERISTICS
5/31/22
Loader J, Taylor FC, Lampa E, et al. | J Am Heart Assoc
Aim: To assess the extent of bias in that research and reevaluated RAAS inhibitor-COVID-19 associations in studies without critical risk of bias.
UPDATED
5/31/22
Dzinamarira T, Murewanhema G, Chitungo I, et al.  | J Infect Public Health
Aim: To determine the association of HIV/AIDS comorbidity with COVID-19 mortality.
UPDATED
CLINICAL CHARACTERISTICS
5/31/22
Marin S, Val AM, Peligero MB, et al. | Pharmaceuticals
Aim: To assess and summarise the available literature on the early toxicity of CQ and HCQ alone or in combination with other drugs that have been used to treat COVID-19 in different clinical situations.
UPDATED
CANDIDATE THERAPEUTICS
5/31/22
Kim TH, Kang JW, Jeon SR, et al. | Front Med
Aim: To identify the overall usage prevalence of TCIM interventions for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
5/31/22
Oliveira da Silva Kist ML, Hanzen Andrades GR, Drumond Costa CA, et al. | Clin Nutr ESPEN
Aim: To systematically review the literature on the relation between weight excess and the severity of COVID-19 in children and adolescents.
UPDATED
CLINICAL CHARACTERISTICS
5/26/22
de Sire A, Andrenelli E, Negrini F, et al. | Eur J Phys Rehabil Med
Aim: To investigate the literature on rehabilitation services for COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/26/22
Cascini F, Pantovic A, Al-Ajlouni YA, et al. | EClinicalMedicine
Aim: To synthesize the current evidence regarding the potential role of social media in shaping COVID-19 vaccination attitudes, and to explore its potential for shaping public health interventions to address the issue of vaccine hesitancy.
UPDATED
INFECTION CONTROL
5/25/22
Zeng B, Gao L, Zhou Q, et al. | BMC Med
Aim: To provide a comprehensive overview of the effectiveness profile of COVID-19 vaccines against VOC.
UPDATED
INFECTION CONTROL
5/25/22
Ling RR, Ramanathan K, Sim JJL, et al. | Crit Care
Aim: To characterise changes in mortality over time and elucidate risk factors for poor outcomes in COVID-19 patients receiving ECMO.
UPDATED
CANDIDATE THERAPEUTICS
5/25/22
Epton T, Ghio D, Ballard LM, et al. | Soc Sci Med
Aim: To determine which interventions and behavior change techniques (BCTs) are effective in promoting adherence to distancing and through which potential mechanisms of action (MOAs).
UPDATED
INFECTION CONTROL
5/24/22
Ulloque-Badaracco JR, Mosquera-Rojas MD, Hernandez-Bustamante EA, et al. | Heliyon
Aim: To evaluate the prognostic value of the AGR in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/24/22
O'Mahoney LL, Highton PJ, Kudlek L, et al. | Diabetes Obes Metab
Aim: To identify, appraise and synthesise available evidence on the impact of the pandemic on glycaemic control in people with diabetes.
UPDATED
5/23/22
Kim H, Hughes E, Cavanagh A, et al. | PLoS One
Aim: To conduct a mixed methods systematic review on the impacts of the COVID-19 pandemic on the health of people who experience imprisonment.
UPDATED
5/20/22
Keskin AU, Ciragil P, Topkaya AE | Int J Microbiol
Aim: To collect and analyse current evidence on real-world performance based on clinical accuracy of instrument-read rapid antigen diagnostic tests (Ag-IRRDTs) for SARS-CoV-2 identification.
UPDATED
DIAGNOSTICS
5/19/22
Ackah M, Ameyaw L, Gazali Salifu M, et al. | PLoS One
Aim: To review the acceptance rate and possible reasons for COVID-19 vaccine non-acceptance/hesitancy amongst HCWs in Africa.
UPDATED
INFECTION CONTROL
5/17/22
Alshammary AF, Alsughayyir JM, Alharbi KK, et al. | Front Med
Aim: To analyze T-cell subsets (CD4/CD8) and IL-10 in severe and fatal cases of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/16/22
Toro-Huamanchumo CJ, Benites-Meza JK, Mamani-García CS, et al.  | J Clin Med
Aim: To assess the efficacy of colchicine in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/16/22
Vaseghi N, Sharifisooraki J, Khodadadi H, et al.  | Mycoses
Aim: To evaluate and estimate the global prevalence of coronavirus-associated C. auris infection (CACa).
UPDATED
CLINICAL CHARACTERISTICS
5/16/22
Ruvinsky S, Voto C, Roel M, et al. | Front Pediatr
Aim: To describe the clinical course, laboratory findings, epidemiology, treatment, and use of resources of MIS-C in children from LAC.
UPDATED
CLINICAL CHARACTERISTICS
5/16/22
Santana LADM, Vieira WA, Gonçalo RIC, et al. | J Stomatol Oral Maxillofac Surg
Aim: To better understand the relationship between COVID-19 infection and oral lesions.
UPDATED
CLINICAL CHARACTERISTICS
5/16/22
Fugazzaro S, Contri A, Esseroukh O, et al. | Int J Environ Res Public Health
Aim: To explore the effectiveness of rehabilitation interventions for adult patients with PACS by reporting the main changes in outcomes after the experimental interventions.
UPDATED
5/16/22
Dellafiore F, Arrigoni C, Nania T, et al.  | Acta Biomed
Aim: To synthesize the current evidence on the impact of the COVID-19 pandemic on caregivers' mental health.
UPDATED
MENTAL HEALTH
5/16/22
Chen F, Tian Y, Zhang L, et al. | Int J Infect Dis
Aim: To (1) assess the prevalence of pediatric COVID-19 in family clusters; (2) estimate the household secondary attack rate of children in different periods and variants; (3) compare the transmissibility of SARS-CoV-2 in different age groups and explore its potential determinants.
UPDATED
INFECTION CONTROL
5/12/22
Tavares-Júnior JWL, de Souza ACC, Borges JWP, et al. | Cortex
Aim: To determine any relationship between COVID-19 and cognitive complaints, such as dementia, mild cognitive impairment (MCI), or subjective cognitive decline (SCD).
UPDATED
CLINICAL CHARACTERISTICS
5/12/22
Prasad S, Kalafat E, Blakeway H, et al. | Nat Commun
Aim: To review the effects of COVID-19 vaccination in pregnancy, and on vaccine effectiveness in pregnancy.
UPDATED
INFECTION CONTROL
5/11/22
Kolahdouzan K, Chavoshi M, Bayani R, et al. | Int J Radiat Oncol Biol Phys
Aim: To review studies incorporating WLI for the treatment of COVID-19 pneumonia.
UPDATED
CANDIDATE THERAPEUTICS
5/11/22
Verleye A, Wijtvliet V, Abrams S, et al. | Nephrol Dial Transplant
Aim: To compare the antibody response after two-dose mRNA-1273 versus BNT162b2 vaccination in solid organ transplant (SOT) recipients.
UPDATED
INFECTION CONTROL
4/26/22
Sakur FJ, Ward K, Khatri NN, et al. | JMIR Hum Factors
Aim: To review how self-care behaviours have changed for people with chronic conditions during the COVID-19 pandemic, and what technology they have adopted to manage their conditions during that period.
UPDATED
MENTAL HEALTH
4/26/22
Romeo FJ, Barbagelata L, Chiabrando JG, et al. | Am J Ther
Aim: To conduct an updated systematic review and meta-analysis of randomized clinical trials to assess a potential benefit of colchicine in hospitalized patients with COVID-19 infection.
UPDATED
CANDIDATE THERAPEUTICS
4/22/22
Luo S, Liang Y, Wong THT, et al. | Int J Epidemiol
Aim: To summarize modifiable factors for coronavirus disease 2019 (COVID-19) suggested by Mendelian randomization studies.
UPDATED
4/21/22
Kastora S, Patel M, Carter B, et al. | Endocrinol Diabetes Metab
Aim: To analyse the collective and geographically stratified mortality, ICU admission, ventilation requirement, illness severity and discharge rate amongst patients with diabetes.
UPDATED
CLINICAL CHARACTERISTICS
4/14/22
Daniels NF, Burrin C, Chan T, et al. | Curr Dev Nutr
Aim: To explore the indirect effects of the first year of COVID-19 on obesity and its risk factors.
UPDATED
CLINICAL CHARACTERISTICS
4/14/22
Minkove SJ, Sun J, Li Y, et al. | Rev Med Virol
Aim: To analyse studies presenting the adjusted effects specifically of ICI therapy on either survival, a severe event, or need for hospitalisation in cancer patients presenting with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/14/22
Modica G, Bianco M, Sollazzo F, et al. | Int J Environ Res Public Health
Aim: To assess the event rates of myocarditis detected by Cardiac Magnetic Resonance (CMR) in athletes who recovered from COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/14/22
Ulbrichtova R, Svihrova V, Svihra J | Int J Environ Res Public Health
Aim: To evaluate the prevalence of COVID-19 vaccination among medical students worldwide.
UPDATED
CANDIDATE THERAPEUTICS
4/14/22
Vieira AGDS, Pinto ACPN, Garcia BMSP, et al. | J Physiother
Aim: To review the evidence on the effectiveness and safety of telerehabilitation for people with COVID-19 and post-COVID-19 conditions.
UPDATED
CANDIDATE THERAPEUTICS
4/14/22
Su W, Wang H, Sun C, et al.  | Am J Prev Med
Aim: To assess the association between previous influenza vaccination and COVID-19 on the basis of the available evidence.
UPDATED
4/11/22
Litwinowicz K, Choroszy M, Ornat M, et al. | Sci Rep
Aim: To provide a comprehensive evaluation of the face masks and disposable FFRs effects on human physiology during low, moderate, and high-intensity activities.
UPDATED
INFECTION CONTROL
4/11/22
Thornton GM, Fleck BA, Fleck N, et al. | PLoS One
Aim: To examine the effectiveness of HVAC design features in reducing virus transmission.
UPDATED
INFECTION CONTROL
4/7/22
J Devoe D, Han A, Anderson A, et al. | Int J Eat Disord
Aim: To synthesize the impact of the COVID-19 pandemic on individuals with EDs.
UPDATED
MENTAL HEALTH
4/6/22
Gupta AK, Leslie A, Hewitt JN, et al. | ANZ J Surg
Aim: To characterize outcomes of COVID-19 positive patients undergoing cardiac surgery.
UPDATED
CLINICAL CHARACTERISTICS
4/6/22
Liu M, Mei K, Tan Z, et al.  | Can J Gastroenterol Hepatol
Aim: To evaluate the relationship between liver fibrosis scores and adverse outcomes in patients with COVID-19, as well as potential dose-response association.
UPDATED
CLINICAL CHARACTERISTICS
4/6/22
Calvert C, John J, Nzvere FP, et al. | Glob Health Action
Aim: To report the findings of a rapid systematic review of studies on levels of maternal mortality before and during the COVID-19 pandemic.
UPDATED
CLINICAL CHARACTERISTICS
4/5/22
Ao G, Li A, Wang Y, et al. | Am J Emerg Med
Aim: To investigate the association between opioid usage and COVID-19 prognosis.
UPDATED
4/4/22
Fomenko A, Weibel S, Moezi H, et al. | Rev Med Virol
Aim: To review the evidence on RT-PCR performance in detecting infectious SARS-CoV-2. 
UPDATED
DIAGNOSTICS
4/4/22
Wang Y, Kang L, Chien CW, et al. | Front Cardiovasc Med
Aim: To compare the characteristics, management, and clinical outcomes between the COVID-19 and non-COVID-19 patients concomitant STEMI.
UPDATED
CLINICAL CHARACTERISTICS
4/4/22
Mohanty RR, Biswa Mohan Padhy, Meher BR | J Pharm Pharm Sci
Aim: To determine the efficacy and safety of the pulse dose methyl prednisolone in management of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/1/22
Yasuda H, Mayumi T, Okano H | Infection
Aim: To examine the effects of anticoagulant doses administered to patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/1/22
Ma BM, Tam AR, Chan KW, et al. | Front Med
Aim: To review the evidence on the efficacy and safety of COVID-19 vaccine in patients on RRT.
UPDATED
INFECTION CONTROL
4/1/22
Su Y, Rao W, Li M, et al. | Int Psychogeriatr
Aim: To provide up-to-date pooled estimates of the prevalence of social isolation and loneliness among older adults during the COVID-19 pandemic and other pandemics in the last two decades.
UPDATED
MENTAL HEALTH
3/31/22
Diallo A, Carlos-Bolumbu M, Diallo MH, et al. | Z Gesundh Wiss
Aim: To optimize vaccination strategy, evidence on vaccine efficacy against COVID-19 is needed.
UPDATED
INFECTION CONTROL
3/30/22
Yu SY, Koh DH, Choi M, et al.  | Emerg Microbes Infect
Aim: To investigate the efficacy and safety of interleukin-6 (IL-6) receptor antagonists with standard care treatment in patients with coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
3/28/22
Alboksmaty A, Beaney T, Elkin S, et al. | Lancet Digit Health
Aim: To assess the effectiveness and safety of the use of pulse oximetry in the remote monitoring of patients at home with COVID-19.
UPDATED
3/28/22
Maglietta G, Diodati F, Puntoni M, et al. | J Clin Med
Aim: To identify, in patients who had been hospitalized for COVID-19, which factors already present or emerging during hospitalization, were associated with an increased risk of exhibiting new or persisting symptoms.
UPDATED
CLINICAL CHARACTERISTICS
3/28/22
Batteux E, Mills F, Jones LF, et al. | Vaccines
Aim: To identify and evaluate the effectiveness of interventions which can increase COVID-19 vaccine uptake.
UPDATED
INFECTION CONTROL
3/28/22
Furnica C, Chistol RO, Chiran DA, et al. | Diagnostics
Aim: To evaluate the impact of the early COVID-19 pandemic on the presentation, management, and prognosis of STEMI patients.
UPDATED
CLINICAL CHARACTERISTICS
3/28/22
Bania A, Pitsikakis K, Mavrovounis G, et al. | J Pers Med
Aim: To summarize the most recent evidence regarding the therapeutic role of vitamin D on severe COVID-19 outcomes (length of hospital stay, mechanical ventilation, mortality) in adult populations.
UPDATED
CANDIDATE THERAPEUTICS
3/25/22
Muthuka JK, Kiptoo M, Oluoch K, et al. | JMIR Pediatr Parent
Aim: To examine the relationship between pregnancy status and the clinical COVID -19 severity characterized by cytokine storm.
UPDATED
CLINICAL CHARACTERISTICS
3/25/22
Mutua V, Henry BM, Csefalvay CV, et al. | Acta Biomed
Aim: To explore the clinical benefits and safety of tocilizumab in addition to standard of care (SOC) in treating patients with coronavirus disease 2019 (COVID-19).
UPDATED
CANDIDATE THERAPEUTICS
3/24/22
Alimoradi Z, Ohayon MM, Griffiths MD, et al. | BJPsych Open
Aim: To synthesize empirical evidence to understand fear of COVID-19 and its associations with mental health-related problems during this pandemic period.
UPDATED
3/24/22
Tutal E, Ozaras R, Leblebicioglu H | Travel Med Infect Dis
Aim: To assess the prevalence, clinical features and outcome of autoimmune thyroid disorders triggered by COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/21/22
Crivelli L, Palmer K, Calandri I, et al. | Alzheimers Dement
Aim: To review the evidence on the cognitive effects of coronavirus disease 2019 (COVID-19) in adults with no prior history of cognitive impairment.
UPDATED
MENTAL HEALTH
3/21/22
Wang F, Zhang L, Ding L, et al. | Front Public Health
Aim: To review the evidence on the fear among college students during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/21/22
Lee KW, Ang CS, Lim SH, et al.  | HIV Med
Aim: To assess the prevalence of depression, anxiety, psychological stress, insomnia and loneliness among PLHIV during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/18/22
Rawal S, Tackett RL, Stone RH, et al. | Am J Obstet Gynecol MFM
Aim: To identify and synthesize what is known about COVID-19 vaccination amongst pregnant people in the U.S., including safety, effectiveness, acceptance, hesitancy, and uptake of COVID-19 vaccinations.
UPDATED
INFECTION CONTROL
3/18/22
Mekonnen BD, Mengistu BA | Clin Epidemiol Glob Health
Aim: To estimate the pooled proportion of COVID-19 vaccine acceptance and its determinants in Ethiopia.
UPDATED
INFECTION CONTROL
3/18/22
Fatima M, Ahmad Cheema H, Ahmed Khan MH, et al.  | Ann Med Surg
Aim: To provide a detailed account of the development of myocarditis and pericarditis following the COVID-19 vaccination
UPDATED
CLINICAL CHARACTERISTICS
3/18/22
Qi X, Northridge ME, et al. | Aging Health Res
Aim: To determine the prevalence of oral health conditions in participants with COVID-19 infection and identify the associations of oral health conditions with COVID-19 related outcomes.
UPDATED
CLINICAL CHARACTERISTICS
3/18/22
Jaiswal V, Almas T, Peng Ang S, et al. | Ann Med Surg
Aim: To find the symptoms, risk factors, clinical findings, and outcomes in patient of COVID-19 having STEMI.
UPDATED
CLINICAL CHARACTERISTICS
3/18/22
Silva A, Azevedo M, Sampaio-Maia B, et al. | J Am Dent Assoc
Aim: To assess the effectiveness of mouthrinses in reducing SARS-CoV-2 viral load.
UPDATED
INFECTION CONTROL
3/14/22
Kaya T, Dilek A, Ozaras R, et al. | Travel Med Infect Dis
Aim: To evaluate COVID-19 cases presented with febrile neutropenia and provide information regarding incidence, clinical course and prognosis.
UPDATED
CLINICAL CHARACTERISTICS
3/14/22
Branjerdporn G, Bowman C, Kenworthy S, et al. | Front Psychiatry
Aim: To examine the impact of past viral epidemics on staff mental health interventional responses, with a specific focus on healthcare provider response in the context of the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
3/14/22
Sharma P, Malik S, Wadhwan V, et al. | Rev Med Virol
Aim: To assess the prevalence of oral manifestations in COVID-19 confirmed individuals.
UPDATED
CLINICAL CHARACTERISTICS
3/11/22
 | NSW Health COVID-19 Critical Intelligence Unit
UPDATED
3/11/22
Chen H, Shi H, Liu X, et al. | Front Med
Aim: To evaluate the effect of PR on lung impairment for patients with post-COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/9/22
Kariyawasam RM, Julien DA, Jelinski DC, et al. | Antimicrob Resist Infect Control
Aim: To quantify the prevalence and types of resistant co-infecting organisms in patients with COVID-19 and explore differences across hospital and geographic settings.
UPDATED
3/9/22
Wafa IA, Pratama NR, Sofia NF, et al. | Diabetes Metab J
Aim: To investigate the differences in metabolic control parameters in diabetic patients before and during the lockdown.
UPDATED
CLINICAL CHARACTERISTICS
3/7/22
Hu Y, Kung J, Cave A, et al. | J Pharm Pharm Sci
Aim: To determine the clinical effects of Vitamin D serum concentration in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
3/7/22
Yan Y, Du X, Lai L, et al. | J Geriatr Psychiatry Neurol
Aim: To estimate the prevalence of depressive and anxiety symptoms among older adults with different health conditions can inform mental health services for this population during the corona virus disease-2019 (COVID-19) pandemic.
UPDATED
MENTAL HEALTH
3/4/22
Lee ARYB, Wong SY, Chai LYA, et al. | BMJ
Aim: To compare the efficacy of COVID-19 vaccines between immunocompromised and immunocompetent people.
UPDATED
INFECTION CONTROL
3/4/22
Goyal M, Ray I, Mascarenhas D, et al. | QJM
Aim: To elucidate the clinical findings, laboratory parameters, treatment and outcomes of individuals with Myocarditis after COVID-19 vaccination.
UPDATED
CLINICAL CHARACTERISTICS
3/2/22
Notarte KI, Guerrero-Arguero I, Velasco JV, et al.  | J Med Virol
Aim: To characterize the kinetics of anti-SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) antibodies after the second dose of a primary cycle of COVID-19 mRNA vaccination. 
UPDATED
INFECTION CONTROL
3/2/22
Kang X, Jin D, Jiang L, et al. | Chin Med
Aim: To evaluate the efficacy and explore the mechanisms of TCM for COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
3/2/22
Ben-Aicha S, Buchanan J, Punjabi P, et al. | Perfusion
Aim: To estimate the rate of in-hospital mortality following different treatments on COVID-19 in patients with CVD.
UPDATED
CLINICAL CHARACTERISTICS
3/2/22
Damara FA, Muchamad GR, Anton, et al. | World Neurosurg
Aim: To evaluate the epidemiological characteristics of TBI patients before and during the COVID-19 pandemic.
UPDATED
CLINICAL CHARACTERISTICS
3/2/22
Kaka AS, MacDonald R, Linskens EJ, et al. | Ann Intern Med
Aim: To evaluate the effectiveness and harms of remdesivir for COVID-19.
UPDATED
VA ESP
CANDIDATE THERAPEUTICS
3/2/22
Mittal N, Mittal R, Gupta MC, et al.  | Worldviews Evid Based Nurs
Aim: To systematically review the literature to answer the question: "What is the worldwide prevalence of mental health effects in children and adolescents during the COVID-19 pandemic?".
UPDATED
MENTAL HEALTH
3/2/22
Hannah JR, Ali SS, Nagra D, et al.  | Clin Exp Rheumatol
Aim: To review the evidence on skeletal muscle involvement in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/28/22
Pathirathna ML, Samarasekara BPP, Dasanayake TS, et al. | Healthcare
Aim: To evaluate the maternal, fetal and neonatal effects associated with COVID-19 in pregnancy.
UPDATED
CLINICAL CHARACTERISTICS
2/28/22
Jorda A, Kussmann M, Kolenchery N, et al. | Front Immunol
Aim: To evaluate whether the use of convalescent plasma is associated with improved clinical outcomes in patients with Covid-19.
UPDATED
CANDIDATE THERAPEUTICS
2/28/22
Tian Y, Lu H, Liu X, et al. | Medicine
Aim: To assess whether tricuspid annular plane systolic excursion (TAPSE) could be used as a prognostic tool in patients with coronavirus disease 19 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
2/28/22
Chen F, He Y, Shi Y | Vaccines
Aim: To estimate parents’ and guardians’ willingness to vaccinate their children against COVID-19 and identify the determinants of vaccination intention.
UPDATED
INFECTION CONTROL
2/24/22
Qaderi K, Golezar MH, Mardani A, et al. | Dermatol Ther
Aim: To summarize and integrated the findings of studies regarding cutaneous side effects of COVID-19 vaccines. 
UPDATED
INFECTION CONTROL
2/24/22
Li J, Wang Y, Liu Y, et al.  | Eur J Med Res
Aim: To determine the effect of polymorphisms and mutations in angiotensin-converting enzyme 2 (ACE2) and Type 2 transmembrane serine proteases (TMPRSS2) genes on susceptibility to corona virus disease 2019 (COVID-19) and patient prognosis.
UPDATED
CLINICAL CHARACTERISTICS
2/24/22
Fabião J, Sassi B, Pedrollo EF, et al. | Braz J Med Biol Res
Aim: To study the mechanism behind worse coronavirus disease-19 (COVID-19) outcomes in men and whether the differences between sexes regarding mortality as well as disease severity are influenced by sex hormones.
UPDATED
CLINICAL CHARACTERISTICS
2/23/22
Wang Z, Zhao S, Tang Y, et al. | Eur J Pediatr
Aim: To evaluate the efficacy and safety of using potential drugs: remdesivir and glucocorticoid in treating children and adolescents with COVID-19 and intravenous immunoglobulin (IVIG) in treating MIS-C.
UPDATED
CANDIDATE THERAPEUTICS
2/22/22
Rottler M, Ocskay K, Sipos Z, et al. | Ann Intensive Care
Aim: To summarize the evidence on the efficacy of frailty tools in risk assessment in COVID-19 patients.
UPDATED
2/22/22
Pandey SR, Adhikari Yadav S, Gautam S, et al. | F1000Res
Aim: To evaluate the clinical and radiological effects of LDRT in patients with severe acute respiratory syndrome (SARS) due to COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/22/22
 | Pan American Health Organization
Aim: To review the evidence on the therapeutic options for COVID-19.
UPDATED
2/22/22
Galanis P, Vraka I, Siskou O, et al. | Prev Med
Aim: To estimate parents' willingness and refusal to vaccinate their children against the COVID-19, and to investigate the predictors for their decision.
UPDATED
CANDIDATE THERAPEUTICS
2/21/22
Elvidge J, Summerfield A, Nicholls D, et al. | Value Health
Aim: To review economic evaluations of diagnostic tests and treatments for COVID-19.
UPDATED
2/21/22
Ottisova L, Gillard JA, Wood M, et al. | J Trauma Stress
Aim: To summarize the evidence for the interventions in preventing or reducing adverse mental health outcomes in health care staff, with particular emphasis on PTSD, anxiety, depression, and sleep difficulties.
UPDATED
MENTAL HEALTH
2/21/22
Silveira FM, Mello ALR, da Silva Fonseca L, et al. | Arch Oral Biol
Aim: To integrate the morphological and tissue-based molecular characterization of oral lesions occurring in individuals infected by COVID-19 (OLICs).
UPDATED
CLINICAL CHARACTERISTICS
2/21/22
Pardamean E, Roan W, Iskandar KTA, et al. | Gen Hosp Psychiatry
Aim: To analyze whether patients with pre-existing schizophrenia are at higher risk for Covid-19 mortality.
UPDATED
MENTAL HEALTH
2/17/22
Badenoch JB, Rengasamy ER, Watson C, et al. | Brain Commun
Aim: To determine the prevalence of neuropsychiatric symptoms in survivors of COVID-19.
UPDATED
2/16/22
Schmidbauer ML, Ferse C, Salih F, et al.  | J Clin Med
Aim: To systematically investigate incidence, mortality, radiological subtypes and clinical characteristics of ICH in COVID-19 patients.
UPDATED
2/16/22
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence regarding post-acute and subacute care for COVID-19 patients.
UPDATED
2/16/22
Rezaei S, Hoseinipalangi Z, Rafiei S, et al. | J Affect Disord Rep
Aim: To examine the prevalence of depression and the impact of various factors among hospital staff with a view to organize related programs for reducing the complications of these disorders.
UPDATED
MENTAL HEALTH
2/15/22
Clark SE, Chisnall G, Vindrola-Padros C | EClinicalMedicine
Aim: To identify the supportive and operational strategies used for the flexible de-escalation of ICUs in the context of COVID-19.
UPDATED
2/15/22
Tu J, Mo X, Zhang X, et al. | Expert Rev Respir Med
Aim: To assess the efficacy and safety of corticosteroids in COVID-19 patients compared with standard care or placebo.
UPDATED
CANDIDATE THERAPEUTICS
2/15/22
Uaprasert N, Tangcheewinsirikul N, Rojnuckarin P, et al. | Blood Adv
Aim: To systematically review the clinical features and outcomes of patients with COVID-19 with confirmed HIT.
UPDATED
CLINICAL CHARACTERISTICS
2/15/22
Norhayati MN, Che Yusof R, Azman YM | Front Med
Aim: To estimate the pooled proportion of COVID-19 vaccine acceptance worldwide.
UPDATED
INFECTION CONTROL
2/11/22
Quintanilla-Sánchez C, Salcido-Montenegro A, González-González JG, et al. | Rev Neurosci
Aim: To describe the prevalence and risk of ACVE in patients with severe and nonsevere COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/11/22
Dettmann LM, Adams S, Taylor G | Br J Clin Psychol
Aim: To determine the prevalence of anxiety and depression during the first UK COVID-19 lockdown.
UPDATED
MENTAL HEALTH
2/11/22
Liu N, Yang D, Zhang T, et al. | Int J Infect Dis
Aim: To assess the risk factors for olfactory and gustatory dysfunction in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/11/22
Al Kiyumi MH, Kalra S, Davies JS, Kalhan A | Indian J Endocrinol Metab
Aim: To ascertain the prevalence of VDD in patients with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
2/9/22
Jahrami HA, Alhaj OA, Humood AM, et al. | Sleep Med Rev
Aim: To evaluate the extent of sleep disturbances during the COVID-19 pandemic.
UPDATED
2/8/22
Mendoza JPIM, Ubillús BPT, Bolívar GTS, et al. | Saudi Dent J
Aim: To evaluate the antiviral effect of mouthwashes against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
UPDATED
2/8/22
Abas?yan?k Z, Kurt M, Kahraman T | J Dev Phys Disabil
Aim: To investigate the physical activity changes in people with neurological diseases, and to examine the relationship between physical activity and disease symptoms, and psychosocial factors. 
UPDATED
2/8/22
Shi S, Wang F, Yao H, et al.  | Front Med
Aim: To evaluate the potential effect of CHM on immune related profile compared with routine treatment during COVID-19, and to investigate whether the clinical parameters were improved through the immunity profile based on randomized controlled trials (RCTs).
UPDATED
CANDIDATE THERAPEUTICS
2/8/22
Budi DS, Pratama NR, Wafa IA, et al. | Heliyon
Aim: To critically evaluate and summarize the latest evidence of remdesivir for COVID-19 in terms of its efficacy and safety profile among pregnant women.
UPDATED
CANDIDATE THERAPEUTICS
2/8/22
Wang Y, Zhu K, Dai R, et al. | Front Pharmacol
Aim: To evaluate the efficacy and safety of specific interleukin (IL)-1 inhibitors, specific IL-6 inhibitors, and GM-CSF blockades in the treatment of COVID-19 (at the edge of sepsis) patients.
UPDATED
CANDIDATE THERAPEUTICS
2/8/22
Tan Z, Huang S, Mei K, et al.  | Front Cardiovasc Med
Aim: To determine the prevalence and associated death of ventricular arrhythmia and sudden cardiac death (SCD) in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
2/7/22
Ganesh A, Randall MD | Br J Clin Pharmacol
Aim: To investigate the effects of metformin on outcomes in patients with COVID-19 and DM.
UPDATED
CANDIDATE THERAPEUTICS
2/7/22
Safi-Keykaleh M, Aliakbari F, Safarpour H, et al. | Int J Gynaecol Obstet
Aim: To evaluate the prevalence of postpartum depression during COVID-19.
UPDATED
MENTAL HEALTH
2/7/22
Zhang H, Xie F, Yang B, et al. | Am J Infect Control
Aim: To explore the experience of COVID-19 patients.
UPDATED
MENTAL HEALTH
2/4/22
Norhayati MN, Che Yusof R, Azman MY | Int J Environ Res Public Health
Aim: To ascertain the prevalence of psychological impacts among healthcare providers in the Asian region.
UPDATED
MENTAL HEALTH
2/4/22
Schmidt RA, Genois R, Jin J, et al. | Drug Alcohol Depend
Aim: To examine the early impact of COVID-19 on substance use to assess implications for planning substance use treatment and support systems.
UPDATED
MENTAL HEALTH
2/4/22
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the risk of transmission of COVID-19 within post-secondary institutions and the strategies to mitigate on-campus outbreaks?
UPDATED
2/2/22
 | COVID-END
Aim: To review the evidence on the efficacy and effectiveness of available COVID-19 vaccines for variants of concern.
UPDATED
2/1/22
Tian Y, Wu Q, Li H, et al. | Can Respir J
Aim: To review the evidence on the clinical characteristics of COVID-19 in patients based on geographical regions.
UPDATED
CLINICAL CHARACTERISTICS
2/1/22
Chivese T, Matizanadzo M, Musa O, et al. | Pathog Glob Health
Aim: To estimate the prevalence and longevity of detectable SARS-CoV-2 antibodies and T and B memory cells after recovery.
UPDATED
CLINICAL CHARACTERISTICS
1/31/22
Yang J, D'Souza R, Kharrat A, et al. | Acta Obstet Gynecol Scand
Aim: To review the evidence on pregnancy and neonatal outcomes by comparing the pandemic and pre-pandemic periods.
UPDATED
CLINICAL CHARACTERISTICS
1/31/22
Varikasuvu SR, Thangappazham B, Vykunta A, et al. | Expert Rev Anti Infect Ther
Aim: To evaluate the use of vitamin D intervention on COVID-19 outcomes.
UPDATED
CANDIDATE THERAPEUTICS
1/31/22
Pepera G, Tribali MS, Batalik L, et al. | Rev Cardiovasc Med
Aim: To assess the link between COVID-19 and cardiovascular risk factors, and investigate the prognosis in the case of myocardial injury.
UPDATED
CLINICAL CHARACTERISTICS
1/31/22
Lin WT, Hung SH, Lai CC, et al. | J Med Virol
Aim: To assess the clinical efficacy and safety of neutralizing monoclonal antibodies (mABs) for outpatients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/27/22
Díaz LA, García-Salum T, Fuentes-López E, et al. | Gastroenterol Hepatol
Aim: To assess the clearance time in stools of SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
1/27/22
Kharel M, Sakamoto JL, Carandang RR, et al. | BMJ Glob Health
Aim: To examine the impact of COVID-19 lockdown on children and adolescents' movement behaviours.
UPDATED
1/27/22
Gil-Rodríguez J, Pérez de Rojas J, Aranda-Laserna P, et al. | Eur J Radiol
Aim: To identify the defining LUS findings of COVID-19, and to establish its association to the initial severity of the disease and prognostic outcomes.
UPDATED
CLINICAL CHARACTERISTICS
1/25/22
Thakur B, Pathak M | Indian J Community Med
Aim: To assess the burden of mental health outcomes predominantly on the prevalence of anxiety, depression, stress, and insomnia during COVID-19 global emergency among three group of the population, i.e. frontline health-care workers (FHW), nonFHWs (NFHW) and the general population who are not healthcare workers.
UPDATED
MENTAL HEALTH
1/25/22
Subramaniam A, Shekar K, Afroz A, et al.  | Intern Med J
Aim: To examine associations between frailty and short-term mortality in patients hospitalised with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/25/22
Esmaeili M, Abdi F, Shafiee G, et al. | Int J Prev Med
Aim: To systematically review and pool all available evidence on the olfactory and gustatory dysfunction in COVID-19 patients. 
UPDATED
CLINICAL CHARACTERISTICS
1/24/22
Schmid B, Griesel M, Fischer AL, et al. | J Clin Med
Aim: To analyze the available evidence on HFNC vs. NIV and APP vs. standard of care (SoC) on COVID-19-associated respiratory failure.
UPDATED
1/24/22
Aymerich C, Pedruzo B, Pérez JL, et al. | Eur Psychiatry
Aim: To synthesise the available scientific evidence about the state of mental health of HCWs during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
1/24/22
Focosi D, Franchini M, Tuccori M, et al. | Vaccines
Aim: To evaluate the efficacy and safety of polyclonal intravenous immunoglobulin (IVIG) therapy in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/24/22
Khalid MF, Selvam K, Jeffry AJN, et al. | Diagnostics
Aim: To evaluate the pooled sensitivity and specificity of the commercially available RATs.
UPDATED
DIAGNOSTICS
1/24/22
Jaljaa A, Caminada S, Tosti ME, et al. | BMC Public Health
Aim: To assess the risk of infection of migrants and ethnic minorities in the 53 countries belonging to the World Health Organization European Region, during the first year of the pandemic.
UPDATED
1/24/22
Korang SK, von Rohden E, Veroniki AA, et al. | PLoS One
Aim: To assess the effectiveness and safety of COVID-19 vaccines through analyses of all currently available randomized clinical trials.
UPDATED
CANDIDATE THERAPEUTICS
1/21/22
Bailey AJM, Kirkham AM, Monaghan M, et al. | Curr Oncol
Aim: To review the evidence on the clinical manifestations and outcomes of HCT recipients contracting COVID-19 at all stages following transplant, including both pediatric and adult recipients.
UPDATED
CLINICAL CHARACTERISTICS
1/21/22
Pranata R, Yonas E, Huang I, et al. | Eur J Gastroenterol Hepatol
Aim: To explore the association between the FIB-4 index and the risk of mortality among COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
1/20/22
Fujita-Rohwerder N, Beckmann L, Zens Y, et al. | BMJ Evid Based Med
Aim: To systematically assess the diagnostic accuracy of rapid point-of-care tests for diagnosis of current SARS-CoV-2 infections in children under real-life conditions.
UPDATED
DIAGNOSTICS
1/19/22
Wong K, Farooq Alam Shah MU, Khurshid M, et al. | Ann Med Surg
Aim: To analyze the association of COVID-19 with vasculitis.
UPDATED
CLINICAL CHARACTERISTICS
1/19/22
Haas JW, Bender FL, Ballou S, et al.  | JAMA Netw Open
Aim: To compare the frequencies of AEs reported in the placebo groups of COVID-19 vaccine trials with those reported in the vaccine groups.
UPDATED
CANDIDATE THERAPEUTICS
1/19/22
Qin R, He L, Yang Z, et al.  | Clin Rev Allergy Immunol
Aim: To provide an updated synthesis of the association between immune-related indicators and COVID-19 prognosis.
UPDATED
CLINICAL CHARACTERISTICS
1/19/22
Masuda Y, Teoh SE, Yeo JW, et al. | Sci Rep
Aim: To investigate the effect of the COVID-19 pandemic on the pre-hospital chain of survival. 
UPDATED
1/18/22
Espinoza-Espinoza DAK, Dulanto-Vargas JA, Cáceres-LaTorre OA, et al. | J Int Soc Prev Community Dent
Aim: To evaluate the available evidence about a potential association between PD and the risk of COVID-19 complications.
UPDATED
CLINICAL CHARACTERISTICS
1/18/22
Caruso R, Annaloro C, Arrigoni C, et al. | Acta Biomed
Aim: To systematically synthesize evidence regarding burnout and post-traumatic stress disorder (PTSD) among nurses engaged in the frontline during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
1/18/22
Ao G, Wang Y, Liu F, et al. | Exp Clin Transplant
Aim: To compare the clinical outcomes between kidney transplant recipients and patients on dialysis with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/18/22
Zhang S, Yang Z, Chen ZL, et al. | Evid Based Complement Alternat Med
Aim: To systematically evaluate the efficacy and safety of TMTP for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/18/22
Krishnaratne S, Littlecott H, Sell K, et al. | Cochrane Database Syst Rev
Aim: To assess the effectiveness of measures implemented in the school setting to safely reopen schools, or keep schools open, or both, during the COVID-19 pandemic.
UPDATED
INFECTION CONTROL
1/18/22
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the risk factors associated with severe COVID-19 outcomes in children 12 years and under.
UPDATED
1/18/22
Kumar A, Rai A, Khan MS, et al. | J Tradit Complement Med
Aim: To review the evidence on the efficacy and side effects of herbal medicine supplementation with Western medicine in the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/18/22
Heneghan CJ, Spencer EA, Brassey J, et al. | F1000Res
Aim: To systematically review the evidence on orofecal SARS-CoV-2 transmission.
UPDATED
1/17/22
Danwang C, Noubiap JJ, Robert A, et al. | AIDS Res Ther
Aim: To summarize the available information on the risk of hospitalization, severe disease, and death attributable to HIV in patients with COVID-19 and to determine the proportion of patients co-infected with HIV among patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/12/22
Jdiaa SS, Mansour R, El Alayli A, et al. | J Nephrol
Aim: To summarize the effect of CKD on different outcomes among patients with COVID–19. 
UPDATED
CLINICAL CHARACTERISTICS
1/12/22
Reis S, Popp M, Schmid B, et al. | J Clin Med
Aim: To determine the safety and efficacy of intensified anticoagulation with intermediate or therapeutic doses compared to standard-dose thromboprophylaxis in hospitalised patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
1/11/22
Pranata R, Huang I, Lim MA, et al. | Front Med
Aim: To assess whether elevated De Ritis ratio is associated with poor prognosis in patients with coronavirus 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
1/11/22
Shrestha DB, Sedhai YR, Budhathoki P, et al. | Ann Med Surg
Aim: To assess the value and significance of spontaneous pulmonary barotrauma such as pneumothorax, pneumomediastinum, and subcutaneous emphysema in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/11/22
Hernández-Vásquez A, Chavez-Ecos F, Barrenechea-Pulache A, et al. | PeerJ
Aim: To estimate the seroprevalence and lethality attributable to SARS-CoV-2 in the indigenous population of LAC.
UPDATED
CLINICAL CHARACTERISTICS
1/11/22
Ogungbe O, Kumbe B, Fadodun O, et al. | Int J Cardiol Heart Vasc
Aim: To quantify the association between biomarkers of myocardial injury (troponin), myocardial stretch (NT-proBNP, Gal-3), coagulation (D-Dimer), inflammation (CRP, IL-6) and severe COVID-19 or death in hospitalized patients.
UPDATED
CLINICAL CHARACTERISTICS
1/11/22
Mahmoudi E, Mollazadeh R, Mansouri P, et al. | Clin Cardiol
Aim: To evaluate electrocardiogram (ECG) markers of repolarization heterogeneity in patients hospitalized with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/10/22
Bakr AM, El-Sakka AI, et al. | Int J Impot Res
Aim: To review the evidence on the change in erectile function among patients and health care providers during the COVID-19 pandemic.
UPDATED
1/6/22
Amirian A, Pakzad R, Hasanpour V, et al. | J Matern Fetal Neonatal Med
Aim: To investigate neonatal outcomes among pregnant women with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/6/22
MarraMS ARM, Kobayashi T, Suzuki H, et al. | J Infect
Aim: To review the evidence on the impact of COVID-19 vaccination on neutralizing antibodies and the short-term effectiveness of COVID-19 vaccines among immunocompromised patients to prevent laboratory-confirmed symptomatic COVID-19 infection.
UPDATED
INFECTION CONTROL
1/5/22
Cui Y, Zhao B, Li T, et al. | Brain Res Bull
Aim: To evaluate the association between the risk of ischemic stroke and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
1/3/22
Ceban F, Ling S, Lui LMW, et al. | Brain Behav Immun
Aim: To quantify the proportion of individuals experiencing fatigue and cognitive impairment 12 or more weeks following COVID-19 diagnosis, and to characterize the inflammatory correlates and functional consequences of post-COVID-19 syndrome.
UPDATED
CLINICAL CHARACTERISTICS
1/3/22
Jahan N, Brahma A, Kumar MS, et al. | Int J Infect Dis
Aim: To summarize the seroprevalence of SARS-CoV-2 and quantitatively estimate the pooled seroprevalence of SARS-CoV-2 among the Indian population.
UPDATED
CLINICAL CHARACTERISTICS
12/31/21
Ge J, Ma Y, Wu Z, et al. | Medicine
Aim: To better inform efforts to treat and control the current outbreak with effective anticoagulant treatment strategies for coronavirus disease 2019 patients.
UPDATED
CANDIDATE THERAPEUTICS
12/30/21
Chiu L, Lo C, Shen M, et al. | PLoS One
Aim: To report on the state of the current literature on the use of colchicine in COVID-19 and to investigate the reported clinical outcomes in COVID-19 patients by colchicine usage. 
UPDATED
CANDIDATE THERAPEUTICS
12/29/21
Oliveira MR, Sudati IP, Konzen VM, et al. | Exp Gerontol
Aim: To evaluate the available evidence related to the level of physical activity (PA) of elderly people during the COVID-19 pandemic.
UPDATED
12/29/21
Zhu J, Racine N, Xie EB, et al. | Front Psychiatry
Aim: To examine the global prevalence of clinically significant depression and anxiety among post-secondary students during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
12/29/21
Viner R, Waddington C, Mytton O, et al. | J Infect
Aim: To review the evidence on the extent that children and young people (CYP) under 20 years of age transmit SARS-CoV-2 to other CYP and to adults in household and child-specific (e.g. educational) settings.
UPDATED
CLINICAL CHARACTERISTICS
12/29/21
Racine N, Eirich R, Cooke J, et al. | Infant Ment Health J
Aim: To identify the prevalence of depression and anxiety in parents of young children (
UPDATED
MENTAL HEALTH
12/27/21
Jennings G, Monaghan A, Xue F, et al. | J Clin Med
Aim: To compare the two phases of long COVID, namely ongoing symptomatic COVID-19 and post-COVID-19 syndrome with respect to symptomatology, abnormal functioning, psychological burden, and quality of life.
UPDATED
CLINICAL CHARACTERISTICS
12/27/21
Cuevas-Gonzalez MV, Espinosa-Cristóbal LF, Donohue-Cornejo A, et al. | Medicine
Aim: To identify the main signs and symptoms of COVID-19 in the oral cavity.
UPDATED
CLINICAL CHARACTERISTICS
12/24/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the COVID-19 variant of concern dubbed Omicron.
UPDATED
12/23/21
Katsanos A, Palaiodimou L, Zand R, et al | Stroke
Aim: To evaluate the impact of COVID-19 pandemic on stroke epidemiology and care across the world.
UPDATED
12/23/21
Agarwal N, Mishra S, Ayub A | J Family Med Prim Care
Aim: To find out the impact on the discharge status from hospital of the patients receiving convalescent plasma therapy.
UPDATED
CANDIDATE THERAPEUTICS
12/22/21
Alvarenga MOP, Veloso SRM, Bezerra ALCA, et al. | J Photochem Photobiol
Aim: To analyze the evidence from trials performed in healthcare facilities that assessed UV-C disinfection's ability to reduce manual cleaning failures enhancing the logarithmic reduction of nosocomial pathogens. colonized on surfaces.
UPDATED
INFECTION CONTROL
12/21/21
Sung K, Chang T, Wang Y, et al. | J Chin Med Assoc
Aim: To evaluate the efficacy and safety of SARS-CoV-2 vaccination in IBD patients.
UPDATED
INFECTION CONTROL
12/20/21
Deng D, Liang A, Chui JN, et al. | Nephrology
Aim: To evaluate the effect of the COVID-19 pandemic on access to healthcare for patients with CKD.
UPDATED
12/20/21
Romero Starke K, Reissig D, Petereit-Haack G, et al. | BMJ Glob Health
Aim: To quantify the isolated effect of age on hospitalisation, admission to intensive care unit (ICU), mechanical ventilation and death.
UPDATED
CLINICAL CHARACTERISTICS
12/17/21
Castillo-Perez M, Jerjes-Sanchez C, Castro-Varela A, et al.  | Thromb J
Aim: To determine the therapeutic trends and outcomes in VTE COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
12/17/21
Dhillon RA, Qamar MA, Gilani JA, et al. | Ann Med Surg
Aim: To assess the determinants and disease spectrum of COVID-19 reinfection.
UPDATED
CLINICAL CHARACTERISTICS
12/16/21
Bertini P, Guarracino F, Falcone M, et al. | J Cardiothorac Vasc Anesth
Aim: To summarize evidence from all available studies to assess the mortality of patients with COVID-19 treated with VV ECMO.
UPDATED
CANDIDATE THERAPEUTICS
12/16/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy of face masks in helping to prevent the spread of COVID-19.
UPDATED
12/16/21
Waqar U, Ahmed S, Gardezi SMHA, et al. | Clin Appl Thromb Hemost
Aim: To explore the pathophysiology, epidemiology, diagnosis, management, and prognosis of TTS.
UPDATED
INFECTION CONTROL
12/14/21
Ruksakulpiwat S, Zhou W, Phianhasin L, et al. | Chronic Illn
Aim: To identify the difficulties that caregivers of chronically ill patients experienced during the COVID-19 pandemic and to provide directions for future studies.
UPDATED
MENTAL HEALTH
12/13/21
Burns KEA, Laird M, Stevenson J, et al. | JAMA Netw Open
Aim: To appraise the quality of clinical practice guidelines (CPGs) using the National Academy of Medicine (NAM) criteria.
UPDATED
12/13/21
Pegollo L, Maggioni E, Gaeta M, et al. | Acta Biomed
Aim: To review the evidence on population DCT acceptance.
UPDATED
INFECTION CONTROL
12/13/21
Kollias A, Kyriakoulis KG, Trontzas IP, et al. | J Clin Med
Aim: To assess the risk of in-hospital mortality in hospitalized patients with COVID-19 receiving high (intermediate or therapeutic) versus prophylactic doses of thromboprophylaxis.
UPDATED
CANDIDATE THERAPEUTICS
12/13/21
Alenezi FK, Almeshari MA, Mahida R, et al. | Ren Fail
Aim: To assess the incidence and risk factors of AKI, need for kidney replacement therapy (KRT), and mortality rate among COVID-19 patients with and without ARDS from the first wave of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/13/21
Elisabeth AL, Karlen SB, Magkos F | Aging Dis
Aim: To conduct a thorough analysis of the current literature on the effects of the COVID-19-related lockdowns on diet and physical activity habits in older individuals.
UPDATED
12/9/21
Tiwari S, Kc N, Thapa S, et al. | Middle East Fertil Soc J
Aim: To analyze the overall consequences of COVID-19 on semen parameters and male sex hormones.
UPDATED
CLINICAL CHARACTERISTICS
12/8/21
Teoh SE, Masuda Y, Tan DJH, et al. | Ann Intensive Care
Aim: To evaluate the impact of the pandemic on the incidence and case fatality rate (CFR) of OHCA.
UPDATED
12/8/21
Silva DFO, Cobucci RN, Lima SCVC, et al. | Medicine
Aim: To identify the prevalence of anxiety, depression, and stress among teachers during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
12/7/21
Santos MO, Gonçalves LC, Silva PAN, et al. | J Pediatr
Aim: To describe the main symptoms of MIS-C and characterize its treatment and possible outcomes.
UPDATED
CLINICAL CHARACTERISTICS
12/7/21
Jeyalan V, Storrar J, Wu HHL, et al. | World J Transplant
Aim: To provide an overview of the current literature on the renal histopathological features and mechanistic insights described in association with coronavirus disease 2019 (COVID-19) infection.
UPDATED
CLINICAL CHARACTERISTICS
12/7/21
Ma C, Tu D, Gu J, et al.  | Front Cardiovasc Med
Aim: To explore the predictive value of elevated Mb for adverse outcomes of patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
12/7/21
Sahebi A, Yousefi A, Abdi K, et al.  | Front Psychiatry
Aim: To estimate the overall prevalence of PTSD among HCWs.
UPDATED
MENTAL HEALTH
12/6/21
Ghahramani S, Lankarani KB, Yousefi M, et al. | Front Psychiatry
Aim: To present a comprehensive picture of the prevalence of burnout among healthcare workers during the COVID-19 pandemic.
UPDATED
12/6/21
Yunitri N, Chu H, Kang XL, et al. | Int J Nurs Stud
Aim: To examine the global prevalence and associated risk factors of PTSD in patients/survivors of COVID-19, health professionals, and the population at large.
UPDATED
12/6/21
Mirashrafi S, Moravejolahkami AR, Balouch Zehi Z, et al.  | Clin Nutr ESPEN
Aim: To conduct a rapid review of probiotics with specific emphasis on their potential for early administration in patients at greater risk of SARS-CoV-2 infection.
UPDATED
12/4/21
Decary S, Dugas M, Stefan T, et al. | SPOR
Aim: To review the evidence on care models for persons living with long COVID.
UPDATED
LONG COVID
12/3/21
Khan DSA, Hamid LR, Ali A, et al. | BMC Pregnancy Childbirth
Aim: To assess differences in risk factors, management, complications, and pregnancy and perinatal outcomes in symptomatic vs. asymptomatic pregnant women with confirmed SARS-CoV-2 infection.
UPDATED
CLINICAL CHARACTERISTICS
12/3/21
Curran J, Boulos L, Somerville M, et al. | SPOR
Aim: To review the evidence on the impacts of variants of concern on public health and health systems.
UPDATED
DIAGNOSTICS
12/2/21
Pakzad R, Malekifar P, Shateri Z, et al. | J Clin Lab Anal
Aim: To evaluate the pathogens' coinfection prevalence among COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
11/29/21
Yusof W, Irekeola AA, Wada Y, et al. | Life
Aim: To provide a global mutational profile of SARS-CoV-2 from December 2019 to October 2020.
UPDATED
CLINICAL CHARACTERISTICS
11/29/21
Sagris D, Florentin M, Tasoudis P, et al. | J Clin Med
Aim: To investigate the potential beneficial effect of immunomodulation therapy on the thromboembolic risk in hospitalized COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
11/29/21
Wu HHL, Kalra PA, Chinnadurai R | Vaccines
Aim: To delineate the range of kidney histopathologies that were elicited following COVID-19 vaccination.
UPDATED
INFECTION CONTROL
11/25/21
Rotshild V, Hirsh-Raccah B, Miskin I, et al. | Sci Rep
Aim: To compare the efficacy of new COVID-19 vaccines to prevent symptomatic and severe disease in the adult population and to prevent symptomatic COVID-19 among the elderly. 
UPDATED
INFECTION CONTROL
11/25/21
Iezadi S, Gholipour K, Azami-Aghdash S, et al. | PLoS ONE
Aim: To examine the effects of NPHIs on the COVID-19 case growth rate, death growth rate, Intensive Care Unit (ICU) admission, and reproduction number in countries, where NPHIs have been implemented. 
UPDATED
INFECTION CONTROL
11/24/21
Acuff SF, Strickland JC, Tucker JA, et al. | Psychol Addict Behav
Aim: To examine changes in alcohol consumption during the coronavirus disease (COVID-19) pandemic.
UPDATED
11/24/21
Kaushal K, Kaur H, Sarma P, et al. | J Crit Care
Aim: To evaluate serum ferritin level in different severity levels in COVID-19.
UPDATED
DIAGNOSTICS
11/23/21
Conway R, Grimshaw AA, Konig MF, et al. | Arthritis Rheumatol
Aim: To quantify the risk for SARS-CoV-2 infection and describe clinical outcomes of COVID-19 in people with RMD.
UPDATED
CLINICAL CHARACTERISTICS
11/23/21
Xu W, Li X, Dong Y, et al.  | J Glob Health
Aim: To investigate the extent of SARS-CoV-2 transmission in schools. 
UPDATED
INFECTION CONTROL
11/22/21
Meng Y, Wang J, Wen K, et al. | Biomed Res Int
Aim: To present systematic reviews and detailed estimates of the major symptoms of COVID-19, determine the prevalence of serious comorbidities, and assess patient progression via comorbidities, major symptoms and laboratory examination to help severe patients and effectively reduce the mortality of COVID-19 under the condition of limited medical resources.
UPDATED
CLINICAL CHARACTERISTICS
11/22/21
Becerril-Gaitan A, Vaca-Cartagena BF, Ferrigno AS, et al. | Eur J Cancer
Aim: To assess seroconversion rates based on anti-S IgG titres after partial and complete COVID-19 immunisation among oncological patients compared with non-cancer participants.
UPDATED
CLINICAL CHARACTERISTICS
11/22/21
Bourmistrova NW, Solomon T, Braude P, et al. | J Affect Disord
Aim: To examine the long-term mental health impact of COVID-19.
UPDATED
MENTAL HEALTH
11/22/21
Nagarajan R, Krishnamoorthy Y, Basavarachar V, et al. | J Affect Disord
Aim: To estimate the prevalence of PTSD among the severe cases of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
11/22/21
Zinellu A, Paliogiannis P, Carru C, et al. | Clin Exp Med
Aim: To investigate serum concentrations of hydroxybutyrate dehydrogenase (HBDH), a combined marker of myocardial and renal injury, in hospitalized COVID-19 patients with different disease severity and survival status.
UPDATED
CLINICAL CHARACTERISTICS
11/19/21
Ayerbe L, Risco-Risco C, Forgnone I, et al. | J Antimicrob Chemother
Aim: To summarize the available evidence to date on the beneficial and adverse effects of azithromycin in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/19/21
Nascimento RB, Araujo NS, Silva JC, et al. | Spec Care Dentist
Aim: Evaluate oral manifestations detected in children with MIS-C and KD associated to COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
11/18/21
Amer YS, Titi MA, Godah MW, et al. | J Clin Epidemiol
Aim: To systematically identify and critically assess the clinical practice guidelines (CPGs) for the management of critically ill patients with COVID-19 with the AGREE II instrument.
UPDATED
CANDIDATE THERAPEUTICS
11/18/21
Johns G, Samuel V, Freemantle L, et al. | J Affect Disord
Aim: To provide an estimate of the global prevalence of depression and anxiety symptoms among doctors, based on analysis of evidence from the first year of the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
11/17/21
Ling RR, Sim JJL, Tan FL, et al. | Transfus Med Rev
Aim: To investigate whether convalescent plasma is futile in reducing mortality in patients hospitalized with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/17/21
Tashakori-Miyanroudi M, Souresrafil A, Hashemi P, et al. | Epilepsy Behav
Aim: To investigate the epidemic effect of COVID-19 on increasing the prevalence of mental disorders such as depression, anxiety, and sleep disorders in people with epilepsy (PWE).
UPDATED
MENTAL HEALTH
11/16/21
Du P, Chen W, Luo X, et al. | Ann Palliat Med
Aim: To compare the time intervals from onset to first medical visit and onset to the hospitalization of COVID-19 patients in different regions and assess the supply and demand status of medical resources.
UPDATED
CLINICAL CHARACTERISTICS
11/16/21
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the "test, trace, isolate, and quarantine" strategy advocated by World Health Organization during the COVID-19 pandemic.
UPDATED
11/16/21
Uaprasert N, Panrong K, Rojnuckarin P, et al. | Thromb J
Aim: To determine whether SARS-CoV-2 vaccines increase the risks of thromboembolism and hemorrhage.
UPDATED
INFECTION CONTROL
11/15/21
González-Monroy C, Gómez-Gómez I, Olarte-Sánchez CM, et al. | Int J Environ Res Public Health
Aim: To assess changes in eating behaviour during the COVID-19 pandemic by establishing a comparison of eating behaviours before and after the outbreak of the pandemic. 
UPDATED
MENTAL HEALTH
11/15/21
Arco-Torres A, Cortés-Martín J, Tovar-Gálvez MI, et al. | J Clin Med
Aim: To compile existing knowledge about currently available drug treatments for COVID-19 in pregnant women.
UPDATED
CANDIDATE THERAPEUTICS
11/15/21
Maraolo AE, Crispo A, Piezzo M, et al.  | J Clin Med
Aim: To compare the use of TCZ with placebo or standard of care (SoC), for the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/11/21
Ngamprasertchai T, Kajeekul R, Sivakorn C, et al. | Infect Dis Ther
Aim: To rank immunomodulators in the treatment of COVID-19 according to their efficacy and safety.
UPDATED
CANDIDATE THERAPEUTICS
11/11/21
Jafar A, Lasso A, Shorr R, et al. | PLoS One
Aim: To evaluate the extent and timing of olfactory recovery following loss due to COVID-19 infection.
UPDATED
CLINICAL CHARACTERISTICS
11/10/21
Roberts A, Rogers J, Mason R, et al. | Drug Alcohol Depend
Aim: To document and interpret the frequency and severity of alcohol and other substance use during the Covid-19 pandemic and their relationship to demographic and mental health variables.
UPDATED
MENTAL HEALTH
11/10/21
Abdullah EK, Velladath SU, Varghese A, et al. | Clin Epidemiol Glob Health
Aim: To review the evidence on depression and anxiety associated with COVID- 19 pandemic among healthcare professionals in India.
UPDATED
MENTAL HEALTH
11/10/21
Zanirati G, Provenzi L, Libermann LL, et al.  | NPJ Regen Med
Aim: To investigate different types of stem cells as treatments for COVID-19 and ARDS to evaluate the safety and potential efficacy of cell therapy. 
UPDATED
CANDIDATE THERAPEUTICS
11/9/21
Chen WC, Hsu CK, Chen CY, et al. | Expert Rev Anti Infect Ther
Aim: To investigate the efficacy of interferon (IFN)-beta-containing regimens in treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/8/21
Pecoraro V, Negro A, Pirotti T, et al. | Eur J Clin Invest
Aim: To estimate the rate of RT-PCR false-negatives at initial testing for COVID-19.
UPDATED
DIAGNOSTICS
11/8/21
Li M, Yang X, Jiang L, et al. | BMJ Open
Aim: To comprehensively and objectively evaluate the safety and immunogenicity of inactivated SARS-CoV-2 vaccines in healthy individuals.
UPDATED
INFECTION CONTROL
11/8/21
Souza Botelho M, Bolfi F, Leite RGOF, et al. | Syst Rev
Aim: To evaluate the safety of CQ and HCQ from malarial and non-malarial randomized clinical trials (RCTs).
UPDATED
11/8/21
Fu W, Sivajohan B, McClymont E, et al. | Int J Gynaecol Obstet
Aim: To summarize the safety, immunogenicity, and effectiveness of COVID-19 vaccines in pregnancy and lactation.
UPDATED
INFECTION CONTROL
11/8/21
Byambasuren O, Beller E, Clark J, et al. | Antimicrob Resist Infect Control
Aim: To synthesize all available research on the potential impact of eye protection on transmission of SARS-CoV-2.
UPDATED
INFECTION CONTROL
11/8/21
Margarucci LM, Enrico M, GIanfranceschi G, et al.  | Acta Biomed
Aim: To assess whether low serum 25-OHD is associated with susceptibility to COVID 19, their severity, and mortality. 
UPDATED
CLINICAL CHARACTERISTICS
11/8/21
Rawat D, Roy A, Maitra S, et al. | Diabetes Metab Syndr
Aim: To find out the impact of Vitamin-C administration on major clinical outcomes (mortality, ICU admission, hospital stay, mechanical ventilation) in patients diagnosed with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/8/21
Sofi F, Dinu M, Reboldi G, et al. | Int J Cardiol
Aim: To investigate whether differences in COVID-19 epidemiology or public health-related factors could explain discrepant findings in different countries.
UPDATED
11/5/21
Parashar S, Karthik AR, Gupta R, et al. | Indian J Crit Care Med
Aim: To systemically appraise and summarize the available literature regarding the role of awake proning in the management of COVID-19 novel coronavirus pneumonia.
UPDATED
CANDIDATE THERAPEUTICS
11/5/21
Heidarpour M, Abhari AP, Sadeghpour N, et al. | Diabetes Metab Syndr
Aim: To investigate the clinical outcome of COVID-19 in patients with prediabetes
UPDATED
CLINICAL CHARACTERISTICS
11/5/21
Karki SJ, Joachim A, Heinsohn T, et al. | BMJ Open
Aim: To summarise the comparative risk of infection in school staff and their contribution to SARS-CoV-2 transmission.
UPDATED
INFECTION CONTROL
11/5/21
Damara FA, Muchamad GR, Ikhsani R, et al. | Diabetes Metab Syndr
Aim: To summarize recent findings on the relationship between thyroid disease and COVID-19 outcome.
UPDATED
CLINICAL CHARACTERISTICS
11/4/21
Quincho-Lopez A, Benites-Ibarra CA, Hilario-Gomez MM, et al. | PLoS One
Aim: To assess the prevalence of self-medication for the prevention or management of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
11/4/21
Vaselli NM, Hungerford D, Shenton B, et al. | PLoS One
Aim: To review the evidence on the seroprevalence of SARS-CoV-2 in Europe.
UPDATED
INFECTION CONTROL
11/3/21
Hoang MP, Staibano P, McHugh T, et al. | Int Forum Allergy Rhinol
Aim: To assess the sensitivity of self-reporting and psychophysical tests for OGD.
UPDATED
CLINICAL CHARACTERISTICS
11/3/21
Lindsay RK, Wilson JJ, Trott M, et al. | Ann Med
Aim: To synthesise the recommendations for returning athletes who have experienced long COVID symptoms.
UPDATED
CLINICAL CHARACTERISTICS
11/2/21
Lee JX, Chieng WK, Lau SCD, et al. | Front Med
Aim: To provide an overview of the clinical profile, including the clinical presentations, laboratory, and radiological findings, as well as the outcome of COVID-19 infection among patients with hemoglobinopathy.
UPDATED
CLINICAL CHARACTERISTICS
11/2/21
Funakoshi K, Morita T, Kumanogoh A | Front Med
Aim: To review the clinical course among intubated survivors, non-survivors, and extracorporeal membrane oxygenation (ECMO) patients to reveal the standard clinical course and the difference among critical COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
11/2/21
Li Z, Shao W, Zhang J, et al. | Front Cardiovasc Med
Aim: To clarify the prevalence and clinical impact of AF and new-onset AF in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
11/1/21
Smith CM, Gilbert EB, Riordan PA, et al. | Gen Hosp Psychiatry
Aim: To describe the comorbidities, presentations, and outcomes of adults with incident psychosis and a history of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
11/1/21
Amorim dos Santos J, Normando AGC, Carvalho da Silva RL, et al. | J Dent Res
Aim: To provide a comprehensive up-to-date summary of oral manifestations in patients with COVID-19.
UPDATED
10/29/21
Appleton R, Williams J, Vera San Juan N, et al. | J Med Internet Res
Aim: To investigate the adoption and impacts of telemental health approaches during the COVID-19 Pandemic, and facilitators and barriers to optimal implementation.
UPDATED
10/28/21
Belletti A, Campochiaro C, Marmiere M, et al. | Ann Intensive Care
Aim: To review the evidence on the use IL-6 inhibitors to treat COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/27/21
Kamal A, Hodson A, Pearce JM | Vaccines
Aim: To identify factors influencing COVID-19 vaccination uptake between minority ethnic groups in the UK.
UPDATED
INFECTION CONTROL
10/27/21
Mahamat-Saleh Y, Fiolet T, Rebeaud ME, et al.  | BMJ Open
Aim: To investigate the association between diabetes, hypertension, body mass index (BMI) or smoking with the risk of death in patients with COVID-19 and to estimate the proportion of deaths attributable to these conditions.
UPDATED
CLINICAL CHARACTERISTICS
10/26/21
Ponsford MJ, Ward TJC, Stoneham SM, et al. | Front Immunol
Aim: To investigate the risk of mortality and critical care admission in hospitalised adults with nosocomial COVID-19, relative to adults requiring hospitalisation due to community-acquired infection.
UPDATED
CLINICAL CHARACTERISTICS
10/26/21
Mayo M, Potugari B, Bzeih R, et al. | Mayo Clin Proc Innov Qual Outcomes
Aim: To assess the impact of measures designed to mitigate the spread of COVID-19 on worldwide cancer screening.
UPDATED
INFECTION CONTROL
10/26/21
van Hattum JC, Spies JL, Verwijs SM, et al. | BMJ Open Sport Exerc Med
Aim: To provide a comprehensive overview of myocardial and pericardial involvement after SARS-CoV-2 infection, long-term cardiac sequelae after infection and risks of sudden cardiac arrest/sudden cardiac death (SCA/SCD) in athletes.
UPDATED
CLINICAL CHARACTERISTICS
10/26/21
Freiberg A, Horvath K, Hahne TM, et al. | Bundesgesundheitsblatt
Aim: To review the evidence on the effects of mask-wearing for preventing infectious diseases on the psychosocial development of children and adolescents.
UPDATED
MENTAL HEALTH
10/26/21
Scquizzato T, Landoni G, Scandroglio AM, et al. | Eur J Emerg Med
Aim: To assess outcomes of SARS-CoV-2 patients with out-of-hospital cardiac arrest.
UPDATED
CLINICAL CHARACTERISTICS
10/25/21
Kumar S, Saurabh MK, Narasimha VL, et al. | Clin Drug Invest
Aim: To determine the efficacy of interferon-beta among moderate-to-severe COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/25/21
Parvu V, Gary DS, Mann J, et al. | Front Microbiol
Aim: To assess the diagnostic accuracy of SARS-CoV-2 antigen detection in COVID-19 symptomatic and asymptomatic individuals compared to quantitative reverse transcription polymerase chain reaction (RT-qPCR) and summarizes antigen test sensitivity using meta-regression.
UPDATED
DIAGNOSTICS
10/25/21
de Araujo CM, Guariza-Filho O, Gonçalves FM, et al. | Int Arch Occup Environ Health
Aim: To analyze the effectiveness of the use of PPE in closed environments, in situations similar to waiting rooms or examination rooms of healthcare facilities, in the face of exposure to a bioaerosol.
UPDATED
INFECTION CONTROL
10/25/21
Mattey-Mora PP, Begle CA, Owusu CK, et al. | Rev Med Virol
Aim: To systematically assess COVID-19 patient background characteristics and pre-existing comorbidities associated with hospitalisation status. 
UPDATED
CLINICAL CHARACTERISTICS
10/25/21
Podury S, Srivastava S, Khan E, et al. | Brain Sci
Aim: To review the data on CNS and PNS inflammatory disorders in COVID-19 with respect to CSF, serum and neuroimaging markers.
UPDATED
CLINICAL CHARACTERISTICS
10/22/21
Popp M, Stegemann M, Riemer M, et al. | Cochrane Database Syst Rev
Aim: To assess the efficacy and safety of antibiotics compared to each other, no treatment, standard of care alone, placebo, or any other active intervention with proven efficacy for treatment of COVID-19 outpatients and inpatients.
UPDATED
CANDIDATE THERAPEUTICS
10/22/21
Yang Z, Wang X, Wan XG, et al.  | Pediatr Pulmonol
Aim: To understand the relationship between the COVID-19 pandemic and asthma outcomes.
UPDATED
CLINICAL CHARACTERISTICS
10/22/21
Farooq S, Tunmore J, Ali W, et al. | Psychiatry Res
Aim: To systematically review the evidence about suicide, self-harm and suicidal ideation during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
10/20/21
Wang L, Zhang Y, Wang D, et al. | Front Med
Aim: To review the application of Artificial Intelligence (AI) techniques in COVID-19, especially for diagnosis, estimation of epidemic trends, prognosis, and exploration of effective and safe drugs and vaccines.
UPDATED
DIAGNOSTICS
10/20/21
Ouma OK, Ephraim K, Loyce N, et al. | BMJ Open
Aim: To determine the diagnostic test accuracy, cost-effectiveness and utility of laboratory test strategies for COVID-19 in low-income and middle-income countries.
UPDATED
DIAGNOSTICS
10/20/21
Rocha YM, de Moura GA, Desidério GA, et al. | Z Gesundh Wiss
Aim: To evaluate the impact of the media and the media during the pandemic caused by the new coronavirus, and to determine how the spread of infodemic impacts people’s health.
UPDATED
MENTAL HEALTH
10/18/21
Pearce LA, Vaisey A, Keen C, et al. | Health Justice
Aim: To identify, collate, and summarise guidance for the prevention and control of COVID-19 in custodial settings in the first six months of 2020.
UPDATED
INFECTION CONTROL
10/18/21
Li J, Liao X, Zhou Y, et al. | BMC Infect Dis
Aim: To evaluate this potential effect from glucocorticoids treatment for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/18/21
Harder T, Külper-Schiek W, Reda S, et al. | Euro Surveill
Aim: To assess the extent to which COVID-19 vaccines are able to prevent symptomatic and asymptomatic infections to guide public health recommendations and develop strategies for fully vaccinated people.
UPDATED
INFECTION CONTROL
10/18/21
Mulyadi M, Tonapa SI, Luneto S, et al. | Nurse Educ Pract
Aim: To identify the prevalence of mental health problems and sleep disturbances among nursing students during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
10/18/21
Behrmann JT, Blaabjerg J, Jordansen J, et al. | J Atten Disord
Aim: To provide a systematic review of evidence regarding the COVID-19's impact on mental health of individuals with ADHD during the COVID-19 lockdown.
UPDATED
MENTAL HEALTH
10/15/21
Cao H, Ming L, Chen L, et al. | Front Med
Aim: To evaluate the clinical efficacy and safety of CCP for the COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/15/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the effectiveness, immunogenicity, and safety of COVID-19 vaccines in persons who have had a prior, confirmed COVID-19 infection.
UPDATED
10/14/21
Dorri M, Bazargany MHM, Khodaparast Z, et al. | J Affect Disord Rep
Aim: To summarize the available evidence on the reduced HRQoL and the prevalence of psychiatric problems, including PTSD, depression and anxiety, and HRQoL among COVID-19 survivors.
UPDATED
MENTAL HEALTH
10/14/21
Jayant K, Reccia I, Bachul PJ, et al. | J Clin Med
Aim: To better understand the clinical course of COVID-19 in kidney transplant recipients and to identify factors associated with clinical outcomes and mortality.
UPDATED
CLINICAL CHARACTERISTICS
10/13/21
Chong WH, Saha BK, Medarov BI | J Intensive Care Med
Aim: To compare the clinical characteristics between COVID-19 survivors and nonsurvivors requiring ECMO support.
UPDATED
CLINICAL CHARACTERISTICS
10/13/21
Peters A, Lotfinejad N, Palomo R, et al. | Antimicrob Resist Infect Control
Aim: To assess the microbiological efficacy of decontamination methods of N95/FFP2 respirators. 
UPDATED
INFECTION CONTROL
10/13/21
Ariyo K, Canestrini S, David AS, et al. | BMJ Open
Aim: To explore patient-assessed quality of life (QoL) in ICU survivors before the COVID-19 pandemic.
UPDATED
10/12/21
Mahat RK, Rathore V, Singh N, et al. | Clin Nutr ESPEN
Aim: To evaluate the association of lipid parameters (total cholesterol, HDL-cholesterol, LDL-cholesterol, and triacylglycerols) with the severity and mortality in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
10/12/21
Shrestha DB, Budhathoki P, Raut S, et al. | World J Virol
Aim: To analyze the rate of new-onset diabetes in COVID-19 patients and compare their clinical outcomes with those of other COVID-19 patients who had normal or increased blood sugar levels or a pre-existing diagnosis of diabetes.
UPDATED
10/12/21
Renaud-Charest O, Lui LMW, Eskander S, et al. | J Psychiatr Res
Aim: To synthesize the extant evidence reporting on the frequency and factors associated with depression in post-COVID-19 syndrome.
UPDATED
CLINICAL CHARACTERISTICS
10/12/21
Soetedjo NNM, Iryaningrum MR, Damara FA, et al. | Clin Nutr ESPEN
Aim: To evaluate the prognostic properties of hypoalbuminemia for poor prognosis and factors that may influence the relationship.
UPDATED
CLINICAL CHARACTERISTICS
10/12/21
Wu X, Li W, Qin Z, et al.  | Medicine
Aim: To evaluate the efficacy and safety of TCM assisted in conventional treatment in the treatment of mild and common COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/5/21
Tibubos AN, Otten D, Ernst M, et al. | Front Psychiatry
Aim: To explore whether there are sex- and gender-dependent vulnerabilities to poor mental health outcomes and risk behaviors in the COVID-19 pandemic?
UPDATED
MENTAL HEALTH
10/5/21
Du XQ, Shi LP, Cao WF, et al. | Front Pharmacol
Aim: To critically evaluate the effectiveness and safety of honeysuckle for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
10/5/21
Kan C, Zhang Y, Han F, et al. | Front Endocrinol
Aim: To assess various antidiabetic agents’ association with mortality in patients with type 2 diabetes (T2DM) who have coronavirus disease 2019 (COVID-19).
UPDATED
CLINICAL CHARACTERISTICS
10/5/21
Kyriakopoulos C, Ntritsos G, Gogali A, et al. | Respirology
Aim: To evaluate the efficacy of tocilizumab in the management of hospitalized COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
10/4/21
Wilairatana P, Masangkay FR, Kotepui KU, et al. | PLoS Negl Trop Dis
Aim: To synthesize, qualitatively and quantitatively, information on the prevalence and characteristics of malaria infection among COVID-19-infected individuals. 
UPDATED
CLINICAL CHARACTERISTICS
10/1/21
Sahebi A, Abdi K, Moayedi S, et al. | J Psychosom Res
Aim: To estimate the prevalence of insomnia in healthcare workers.
UPDATED
CLINICAL CHARACTERISTICS
9/30/21
Singh P, Singh SP, Verma AK, et al. | Visc Med
Aim: To evaluate key imaging manifestations of COVID-19 on abdominal imaging.
UPDATED
CLINICAL CHARACTERISTICS
9/30/21
Aye YN, Mai AS, Zhang A, et al.  | QJM
Aim: To evaluate cardiac complications associated with COVID-19 vaccination.
UPDATED
INFECTION CONTROL
9/30/21
Shah VP, Farah WH, Hill JC, et al.  | Open Forum Infect Dis
Aim: To assess the association between CT values and clinical outcomes, including the risk of hospitalization among patients with COVID-19 and the risk of disease severity and death in such patients.
UPDATED
CLINICAL CHARACTERISTICS
9/30/21
Hajure M, Tariku M, Bekele F, et al.  | Infect Drug Resist
Aim: To provide the latest assessment of healthcare workers’ attitudes toward the COVID-19 vaccination and its contributing factor worldwide.
UPDATED
INFECTION CONTROL
9/30/21
Snow TAC, Saleem N, Ambler G, et al. | Br J Anaesth
Aim: To review the evidence on the use of convalescent plasma in the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/30/21
Cruciani M, Pati I, Masiello F, et al. | Diagnostics
Aim: To review the evidence on the use of ivermectin for the treatment and prophylaxis of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/30/21
Zhou C, Zhao Y, Wang X, et al. | Pediatr Pulmonol
Aim: To characterize the laboratory parameters of MIS-C compared with those of KD and Kawasaki disease shock syndrome (KDSS).
UPDATED
CLINICAL CHARACTERISTICS
9/30/21
Franchini M, Corsini F, Focosi D, et al. | Diagnostics
Aim: To summarize the evidence from the available systematic reviews on the efficacy and safety of CP in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/28/21
Chong WH, Saha BK, Neu KP | Infection
Aim: To assess the clinical characteristics and outcomes of patients diagnosed with CAPA compared to those without CAPA.
UPDATED
CLINICAL CHARACTERISTICS
9/28/21
Deng J, Zhou F, Ali S, et al. | QJM
Aim: To assess the efficacy and safety of ivermectin for treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/27/21
Rubio-Rivas M, Forero CG, Mora-Luján JM, et al. | Pharmacotherapy
Aim: To summarize evidence about the effect of TCZ to treat severe COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/27/21
Wang JG, Mo YF, Su YH, et al. | Medicine
Aim: To systematically analyze the chest CT imaging features of children with COVID-19 and provide references for clinical practice. 
UPDATED
DIAGNOSTICS
9/24/21
Whear R, Abbott RA, Bethel A, et al. | J Adv Nurs
Aim: To review the evidence on the provision of fundamental nursing care to hospitalized patients with a highly infectious virus and the effectiveness of adaptations to overcome barriers to care.
UPDATED
CLINICAL CHARACTERISTICS
9/23/21
Fernandez R, Sikhosana N, Green H, et al. | BMJ Open
Aim: To summarise the evidence relating to the prevalence of anxiety and depression among healthcare workers (HCWs) during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
9/22/21
Sánchez-García V, Hernández-Quiles R, de-Miguel-Balsa E, et al. | J Eur Acad Dermatol Venereol
Aim: To assess the prevalence of COVID-19 (diagnosed using PCR and/or serology) in patients with CLL.
UPDATED
CLINICAL CHARACTERISTICS
9/21/21
Giossi R, Menichelli D, Pani A, et al. | Front Pharmacol
Aim: To evaluate the effectiveness of heparin compared to no anticoagulant treatment in reducing overall mortality.
UPDATED
CANDIDATE THERAPEUTICS
9/21/21
Hossein Kazemi M, Kuhestani Dehaghi B, et al. | Iran J Med Sci
Aim: To explore the possible association of HScore parameters with severity in COVID-19 patients. 
UPDATED
CLINICAL CHARACTERISTICS
9/21/21
Long Q, Li J, Hu X, et al. | Front Med
Aim: To determine the adverse effects on multiple systems and differences between severe and non-severe patients in the post-acute phase.
UPDATED
CLINICAL CHARACTERISTICS
9/21/21
Porter B, Zile A, Peryer G, et al. | Soc Sci Med
Aim: To: i) synthesise evidence describing the experiences of health and social care staff providing end-of-life care during a disease outbreak or humanitarian disaster, ii) understand the impact on their mental health and wellbeing and, iii) identify means of support.
UPDATED
MENTAL HEALTH
9/17/21
Chhibber A, Kharat A, Kneale D, et al. | BMC Public Health
Aim: To measure the extent to which COVID-19 related policies reflect equity considerations by focusing on the global policy landscape around wearing masks and personal protection equipment (PPE).
UPDATED
INFECTION CONTROL
9/17/21
Vardoulakis S, Espinoza Oyarce DA, et al. | Sci Total Environ
Aim: To assess the risk of transmission of viral or bacterial infections through inhalation, surface contact, and faecal-oral routes in public washrooms in healthcare and non-healthcare environments.
UPDATED
INFECTION CONTROL
9/16/21
Siddiquea BN, Shetty A, Bhattacharya O, et al. | BMJ Open
Aim: To assess the knowledge, attitude and practice (KAP) of the global general population regarding COVID-19.
UPDATED
INFECTION CONTROL
9/16/21
Barceló MA, Saez M | Environ Sci Eur
Aim: To assess the methodological limitations in studies that evaluated the effects of environmental and socioeconomic variables on the spread of COVID-19.
UPDATED
INFECTION CONTROL
9/15/21
Mawalla WF, Njiro BJ, Bwire GM, et al. | EJHaem
Aim: To gather current evidence on the transmission of SARS?CoV?2 via blood and its derivatives.
UPDATED
INFECTION CONTROL
9/15/21
Ortega-Paz L, Galli M, Capodanno D, et al. | Eur Heart J Cardiovasc Pharmacother
Aim: To review the evidence on the clinical impact of different prophylactic anticoagulation regimens among hospitalized patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
9/15/21
Ming W, Zuo J, Han J, et al. | Eur Arch Otorhinolaryngol
Aim: To analyze the impact of AAD on the severity and mortality of COVID-19 patients and compare clinical outcomes between patients with and without AAD.
UPDATED
CLINICAL CHARACTERISTICS
9/14/21
Liu L, Ni SY, Yan W, et al. | EClinicalMedicine
Aim: To assess the overall and type-specific risk of mental and neurological disorders for COVID-19 infection and clinical outcomes. 
UPDATED
CLINICAL CHARACTERISTICS
9/13/21
Prakash J, Bhattacharya PK, Yadav AK, et al. | J Crit Care
Aim: To determine the predictive accuracy of the ROX index for predicting HFNC failure in COVID-19 patients with AHRF.
UPDATED
CLINICAL CHARACTERISTICS
9/13/21
Mahroum N, Watad A, Bridgewood C, et al. | Int J Environ Res Public Health
Aim: To investigate whether tocilizumab therapy directed against severe COVID-19 improved survival. 
UPDATED
CANDIDATE THERAPEUTICS
9/9/21
Zinellu A, Paliogiannis P, Fois AG, et al. | Front Public Health
Aim: To capture and interpret the available evidence regarding the relationship between COVID-19 and lipid profile.
UPDATED
CLINICAL CHARACTERISTICS
9/9/21
Li Y, Yang X, Yan P, et al. | Front Med
Aim: To explore the impact of metformin use on COVID-19 mortality and other patient-important outcomes across various populations and studies.
UPDATED
CANDIDATE THERAPEUTICS
9/9/21
Corica B, Marra AM, Basili S, et al. | Sci Rep
Aim: To evaluate the prevalence of RVD and associated outcomes in patients with COVID-19
UPDATED
CLINICAL CHARACTERISTICS
9/9/21
Ciapponi A, Bardach A, Mazzoni A, et al. | Vaccine
Aim: To evaluate the effects of COVID-19 vaccines that the COVAX-MIWG selected in August 2020, or their components used in other vaccines, on pregnancy safety outcomes.
UPDATED
INFECTION CONTROL
9/8/21
Keng BMH, Gan WH, Tam YC, et al. | JAAD Int
Aim: To determine common PPE-related dermatoses, affected body sites, and implicated occupational contactants.
UPDATED
INFECTION CONTROL
9/8/21
Tan X, Guo J, Chen Z, et al. | Therap Adv Gastroenterol
Aim: To report on clinical outcomes of COVID-19 patients who underwent GI endoscopy.
UPDATED
CLINICAL CHARACTERISTICS
9/8/21
Malekifar P, Pakzad R, Shahbahrami R, et al. | Biomed Res Int
Aim: To identify the viral coinfection prevalence among infected people with SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
9/7/21
Sari Motlagh R, Abufaraj M, Karakiewicz PI, et al.  | World J Urol
Aim: To assess the risk of SARS-CoV-2 infection and the severity of disease in PCa patients treated with ADT. 
UPDATED
CLINICAL CHARACTERISTICS
9/7/21
Kamarullah W, Sabrina AP, Rocky MA, et al. | Indian Heart J
Aim: To evaluate the effect of the COVID-19 pandemic on the delivery of care systems and clinical outcomes in STEMI patients.
UPDATED
INFECTION CONTROL
9/7/21
Kim JY, Han K, Suh YJ | J Cardiovasc Magn Reson
Aim: To investigate the prevalence of abnormal CMR findings in recovered COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
9/3/21
Bryant A, Lawrie TA, Dowswell T, et al. | Am J Ther
Aim: To assess the efficacy of ivermectin treatment among people with covid-19 infection and as a prophylaxis among people at higher risk of COVID-19 infection.
UPDATED
CANDIDATE THERAPEUTICS
8/31/21
Wang Q, Zhu H, Li M, et al. | Front Pharmacol
Aim: To evaluate the efficacy and safety of QFPD in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/31/21
Dutta A, Sharma A, Torres-Castro R, et al. | Indian J Psychiatry
Aim: To synthesise the currently available literature on the topic to determine the prevalence of mental health problems in healthcare workers.
UPDATED
MENTAL HEALTH
8/30/21
Khandker SS, Nik Hashim NHH, Deris ZZ, et al. | J Clin Med
Aim: To provide an update on the diagnostic accuracy in terms of estimating the specificity and sensitivity of RAT kits in patients with suspected COVID-19.
UPDATED
DIAGNOSTICS
8/30/21
Madewell ZJ, Yang Y, Longini IM Jr, et al. | JAMA Netw Open
Aim: To examine evidence for household transmission of SARS-CoV-2, disaggregated by several covariates, and to compare it with other coronaviruses.
UPDATED
INFECTION CONTROL
8/30/21
Sanchez-Ramirez DC, Normand K, Zhaoyun Y, et al. | Biomedicines
Aim: To explore persistent effects of COVID-19 beyond 3 months follow-up on patient chest computed tomography (CT), lung function, respiratory symptoms, fatigue, functional capacity, quality of life, and the ability to return to work. 
UPDATED
CLINICAL CHARACTERISTICS
8/30/21
Chen J, Cai Y, Chen Y, et al. | Vaccines
Aim: To calculate the pooled event rate of NMAEs after COVID-19 vaccination.
UPDATED
INFECTION CONTROL
8/30/21
Treskova-Schwarzbach M, Haas L, Reda S, et al. | BMC Med
Aim: To summarise the evidence on age-adjusted associations between multiple pre-existing health conditions and clearly defined COVID-19 outcomes separating the effects between the geographical regions.
UPDATED
CLINICAL CHARACTERISTICS
8/30/21
de Labry-Lima AO, Bermudez-Tamayo C, Martinez-Olmos J, et al. | Enferm Infecc Microbiol Clin
Aim: To compile the available evidence on the use of masks in relation to respiratory infections.
UPDATED
INFECTION CONTROL
8/30/21
Munro A, Booth H, Gray NM, et al. | Int J Environ Res Public Health
Aim: To inform current and future responses to coronavirus outbreaks by identifying and critically appraising the empirical evidence relating to the impact of novel coronavirus outbreaks of the 21st Century on problem drug users, with a particular focus on COVID-19
UPDATED
INFECTION CONTROL
8/27/21
Sarkar S, Kannan S, Khanna P, et al  | J Med Virol
Aim: To explore the utility of PLR as a prognostic predictor of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/23/21
Andreas M, Piechotta V, Skoetz N, et al. | Cochrane Database Syst Rev
Aim: To assess the efficacy and safety of pharmacological and non-pharmacological interventions for palliative symptom control in individuals with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/23/21
Busch IM, Moretti F, Mazzi M, et al. | Psychotherapy and Psychosomatics
Aim: To comprehensively synthesize and quantify the psychological and psychosomatic symptoms of healthcare providers on the frontline of past epidemics/pandemics (i.e., Ebola, H1N1, SARS, MERS) and the current pandemic (i.e., COVID-19).
UPDATED
MENTAL HEALTH
8/17/21
Lee M, Lim H, Xavier MS, et al. | J Relig Health
Aim: To summarize the roles that religious communities played during the early stage of COVID-19 pandemic.
UPDATED
8/17/21
Walsh S, Chowdhury A, Braithwaite V, et al.  | BMJ Open
Aim: To summarise observational evidence of the effect of school closures and school reopenings on SARS-CoV-2 community transmission.
UPDATED
INFECTION CONTROL
8/17/21
Kyriazopoulou E, Huet T, Cavalli G, et al. | Lancet Rheumatol
Aim: To assess the effect of anakinra treatment on mortality in patients admitted to hospital with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/17/21
Wagner C, Griesel M, Mikolajewska A, et al. | Cochrane Database Syst Rev
Aim: To assess whether systemic corticosteroids are effective and safe in the treatment of people with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/16/21
Sunjaya AP, Allida SM, Di Tanna GL, et al. | Eur Respir J
Aim: To review the evidence on whether people with asthma at a higher risk of being infected, hospitalised or of poorer clinical outcomes from COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
8/16/21
Zinellu A, Mangoni AA | J Nephrol
Aim: To review the evidence on the effectiveness of serum cystatin C in COVID-19 in treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
8/16/21
Chekole YA, Abate SM | Ann Med Surg
Aim: To assess the global prevalence and determinants of mental health disorders.
UPDATED
MENTAL HEALTH
8/16/21
Scquizzato T, D'Amico F, Rocchi M, et al. | Prehosp Emerg Care
Aim: To analyse how the pandemic impacted the system-of-care of out-of-hospital cardiac arrest.
UPDATED
INFECTION CONTROL
8/16/21
Brummer LE, Katzenschlager S, Geaddert M, et al.  | PLoS One
Aim: To assess the clinical accuracy (sensi-tivity and specificity) of commercially available Ag-RDTs.
UPDATED
DIAGNOSTICS
8/16/21
Suárez-González A, Rajagopalan J, Livingston G, et al. | EClinicalMedicine
Aim: To examine and summarise the global research evidence describing the effect of Covid-19 isolation measures on the health of people living with dementia.
UPDATED
MENTAL HEALTH
8/13/21
AbdelHamid S, Refaat AA, Benjamin AM, et al. | Environ Sci Pollut Res Int
Aim: To study the impact of host or viral epigenetic modulation on COVID-19 infection susceptibility and/or outcome.
UPDATED
CLINICAL CHARACTERISTICS
8/12/21
 | National Collaborating Centre for Methods and Tools
Aim: To review the evidence on the role of daycares and schools in the transmission of COVID-19.
UPDATED
8/11/21
Lopez-Leon S, Wegman-Ostrosky T, Perelman C, et al. | Sci Rep
Aim: To identify studies assessing long-term effects of COVID-19 and estimates the prevalence of each symptom, sign, or laboratory parameter of patients at a post-COVID-19 stage.
UPDATED
CLINICAL CHARACTERISTICS
8/10/21
WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Shankar-Hari M, Vale CL, et al. | JAMA
Aim: To estimate the association between administration of IL-6 antagonists compared with usual care or placebo and 28-day all-cause mortality and other outcomes.
UPDATED
CANDIDATE THERAPEUTICS
8/9/21
Conti V, Corbi G, Sellitto C, et al.  | J Pers Med
Aim: To review and assess the effectiveness of TCZ in reducing the mortality rate in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
8/9/21
Kovoor JG, Tivey DR, Ovenden CD, et al. | BJS Open
Aim: To characterize surgical evolution following COVID-19. 
UPDATED
INFECTION CONTROL
8/9/21
Alves VP, Casemiro FG, Araujo BG, et al. | Int J Environ Res Public Health
Aim: To evaluate the factors associated with mortality of elderly Brazilians and Italians diagnosed with the new coronavirus who resided in institutions or who were hospitalized as a result of the disease.
UPDATED
CLINICAL CHARACTERISTICS
8/9/21
Gómez CA, Sun CK, Tsai IT, et al. | Sci Rep
Aim: To determine, in patients with coronavirus disease 2019 (COVID-19) infection, the associations of pulmonary embolism (PE) with mortality and risk factors for PE as well as the therapeutic benefit of anticoagulant prophylaxis.
UPDATED
CLINICAL CHARACTERISTICS
8/9/21
Prada L, Santos CD, Baião RA, et al. | J Clin Pharmacol
Aim: To systematically evaluate the risk of SARS-CoV-2 infection and mortality and the risk of severe coronavirus disease 2019 (COVID-19) associated with previous exposure to NSAIDs. 
UPDATED
CLINICAL CHARACTERISTICS
8/5/21
Batra K, Sharma M, Batra R, et al. | Healthcare
Aim: To present collective evidence discussing the psychological impact of COVID-19 among college students.
UPDATED
MENTAL HEALTH
8/5/21
Chen C, Chen W, Hsu C, et al. | Int Immunopharmacol
Aim: To investigate the clinical efficacy and safety of Janus kinase (JAK) inhibitors for COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
8/5/21
Rains LS, Johnson S, Barnett P, et al. | Soc Psychiatry Psychiatr Epidemiol
Aim: To map early impacts of the pandemic on people with pre-existing mental health conditions and services they use, and to identify individual and service-level strategies adopted to manage these.
UPDATED
MENTAL HEALTH
8/5/21
Chou R, Dana T, Jungbauer R, et al. | Ann Intern Med
Aim: To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.
UPDATED
8/5/21
Sahu AK, Mathew R, Bhat R, et al. | QJM
Aim: To assess effect of steroids in mild COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
8/4/21
Jiang L, Li Y, Du H, et al. | Front Med
Aim: To clarify whether hospitalized patients with COVID-19 benefit from anticoagulation therapy (including both therapeutic– and prophylactic–dose anticoagulation therapy).
UPDATED
CANDIDATE THERAPEUTICS
8/4/21
Amani B, Amani B, Zareei S, et al. | Immun Inflamm Dis
Aim: To provide the latest evidence on arbidol's efficacy and safety compared with other therapeutic agents in COVID?19 treatment.
UPDATED
CANDIDATE THERAPEUTICS
8/4/21
Vitalakumar D, Sharma A, Kumar A, et al. | ACS Chem Neurosci
Aim: To conduct a meta-analysis of clinical studies associated with neurological problems in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
8/3/21
Yadav AK, Ghosh S, Dubey S | Med J Armed Forces India
Aim: To summarize and synthesize evidence from all available case series and case reports published on re-positive COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
8/3/21
Abate SM, Mantefardo B, Nega S, et al. | Ann Med Surg
Aim: To determine the prevalence, determinants, and outcomes of acute myocardial injury. 
UPDATED
CANDIDATE THERAPEUTICS
8/2/21
Katzenschlager S, Zimmer AJ, Gottschalk C, et al. | PLoS One
Aim: To assess demographic, laboratory and clinical indicators as predictors for severe courses of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
8/2/21
Ansari Ramandi MM, Yarmohammadi H, Beikmohammadi S, et al. | J Cardiovasc Thorac Res
Aim: To gather all possible cardiovascular manifestations of the coronavirus family in the literature. 
UPDATED
CLINICAL CHARACTERISTICS
8/2/21
McGowan VJ, Lowther HJ, Meads C | BMJ Open
Aim: To systematically review all published and unpublished evidence on the impact of the COVID-19 pandemic on the health and well-being of UK sexual and gender minority people.
UPDATED
MENTAL HEALTH
8/2/21
Cammarota G, Esposito T, Azzolina D, et al. | Crit Care
Aim: To summarize the evidence on clinically relevant outcomes in COVID-19 patients supported by NIV outside the ICU.
UPDATED
CANDIDATE THERAPEUTICS
8/2/21
Mittal N, Mittal R, Gupta MC, et al.  | J Family Med Prim Care
Aim: To evaluate the therapeutic potential of CQ/HCQ given alone and in combination with azithromycin for treatment of confirmed COVID-19 infection caused by SARS-CoV-2, in comparison to standard management or other drugs.
UPDATED
CANDIDATE THERAPEUTICS
8/2/21
Ghasemian R, Shamshirian A, Heydari K, et al. | Int J Clin Pract
Aim: To review the evidence on the role of vitamin D in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
7/29/21
Ceban F, Nogo D, Carvalho IP, et al. | JAMA Psychiatry
Aim: To assess whether preexisting mood disorders are associated with a higher risk of COVID-19 susceptibility, hospitalization, severe complications, and death.
UPDATED
CLINICAL CHARACTERISTICS
7/29/21
Zinellu A, Paliogiannis P, Carru C, et al. | Adv Med Sci
Aim: To review the evidence on the international normalized ratio (INR) in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/29/21
Mohsenpour A, Bozorgmehr K, Rohleder S, et al. | EClinicalMedicine
Aim: To review the evidence on SARS-Cov-2 infection, transmission, outcomes of disease, effects of non-pharmaceutical interventions (NPI), and the effectiveness of strategies for infection prevention and control (IPC).
UPDATED
INFECTION CONTROL
7/28/21
Raoofi S, Pashazadeh Kan F, Rafiei S, et al. | BMJ Support Palliat Care
Aim: To systematically review the existing literature examining the prevalence of anxiety among hospital staff and identifying the contributing factors to address the complications of this disorder.
UPDATED
MENTAL HEALTH
7/28/21
Fond G, Nemani K, Etchecopar-Etchart D, et al.  | JAMA Psychiatry
Aim: To determine whether patients with mental health disorders were at increased risk of COVID-19 mortality compared with patients without mental health disorders.
UPDATED
MENTAL HEALTH
7/27/21
Xu H, Stjernswärd S, Glasdam S, et al. | Int J Nurs Stud Adv
Aim: To explore the psychosocial experiences of frontline nurses working in hospital-based settings during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
7/27/21
Zhang K, Zhang X, Ding W, et al. | Front Med
Aim: To evaluate the prognostic accuracy of the NEWS2 on predicting clinical deterioration for patients with COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
7/26/21
Karimi A, Nowroozi A, Alilou S, et al. | Urol J
Aim: To study the effect of androgen deprivation therapy (ADT) on COVID-19 in patients with prostate cancer.
UPDATED
CLINICAL CHARACTERISTICS
7/26/21
Chen X, Chen Z, Azman AS, et al.  | Clin Infect Dis
Aim: To summarize the evidence on neutralization ability against various SARS-CoV-2 variants among those previously infected with strains from the original SARSCoV-2 lineage and those who have been vaccinated
UPDATED
INFECTION CONTROL
7/26/21
Conde-Agudelo A, Romero R | Am J Obstet Gynecol
Aim: To examine the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and the risk of preeclampsia.
UPDATED
CLINICAL CHARACTERISTICS
7/22/21
McGrowder DA, Miller F, Cross MA, et al. | Diseases
Aim: To review the evidence on abnormal liver biochemistry tests in COVID-19 and the possible pathogenesis involved.
UPDATED
CLINICAL CHARACTERISTICS
7/22/21
Zhou Y, O'Leary TJ | PLoS One
Aim: To compare the sensitivity of nasal and nasopharyngeal swabs against a composite reference standard for the initial diagnosis of SARS-CoV-2 infection in ambulatory patients.
UPDATED
DIAGNOSTICS
7/20/21
Vai B, Mazza MG, Delli Colli C, et al. | Lancet Psychiatry
Aim: To assess the specific risks of COVID-19-related mortality, hospitalisation, and intensive care unit (ICU) admission associated with any pre-existing mental disorder, and specific diagnostic categories of mental disorders, and exposure to psychopharmacological drug classes.
UPDATED
CLINICAL CHARACTERISTICS
7/20/21
Cirillo N | J Infect Public Health
Aim: To facilitate a timely understanding of the differences in the prevalence of gustatory disturbances (GD) in individuals infected with SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
7/19/21
Andrianto, Al-Farabi MJ, Nugraha RA, et al. | Microvasc Res
Aim: To assess biomarkers of endothelial cells in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/19/21
Saragih ID, Tonapa SI, Saragih IS, et al. | Int J Nurs Stud
Aim: To systematically identify the mental health problems among healthcare workers in various countries during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
7/19/21
Luo C, Yang Y, Liu Y, et al.  | Am J Infect Control
Aim: To gain insight into willingness and its influencing factors to vaccinate against COVID-19 among health care workers (HCWs).
UPDATED
INFECTION CONTROL
7/19/21
Alkofide H, Almohaizeie A, Almuhaini S, et al. | Int J Infect Dis
Aim: To systematically review the literature on the association between the combination of tocilizumab (TCZ) and systemic corticosteroid therapy (SCT) on outcomes of COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
7/17/21
John A, Eyles E, Webb RT, et al.  | F1000Research
Aim: To identify and appraise any newly published evidence from around the world that assesses the impact of the COVID-19 pandemic on suicide deaths, suicidal behaviours, self-harm and suicidal thoughts, or that assesses the effectiveness of strategies to reduce the risk of suicide deaths, suicidal behaviours, self-harm and suicidal thoughts, resulting from the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
7/16/21
Franceschi VB, Santos AS, Glaeser AB, et al. | Rev Med Virol
Aim: To evaluate the qualitative aspects of population-based seroprevalence surveys of COVID-19, including their reliability and biases.
UPDATED
7/16/21
Agarwal L, Agarwal A, Advani S, et al. | BR J Radiol
Aim: To scope the existing literature on the abdominal imaging findings in COVID-19.
UPDATED
7/15/21
 | EUnetHTA
Aim: To review the evidence on the use of anakinra for the treatment for COVID-19.
UPDATED
7/15/21
 | EUnetHTA
Aim: To review the evidence on the use of APN01 for the treatment for COVID-19.
UPDATED
7/15/21
 | EUnetHTA
Aim: To review the evidence on the use of aspirin for the treatment for COVID-19.
UPDATED
7/15/21
 | EUnetHTA
Aim: To review the evidence on the use of baricitinib for the treatment for COVID-19.
UPDATED
7/15/21
 | EUnetHTA
Aim: To review the evidence on the use of camostat for the treatment for COVID-19.
UPDATED
7/15/21
Jiang F, Xu N, Zhou Y, et al. | Phytother Res
Aim: To review the efficacy and safety of treating COVID-19 with combined traditional Chinese medicine (TCM) and conventional western medicine (CWM).
UPDATED
CANDIDATE THERAPEUTICS
7/15/21
Karakike E, Giamarellos-Bourboulis EJ, Kyprianou M, et al. | Crit Care Med
Aim: To describe the prevalence of coronavirus disease 2019-related sepsis.
UPDATED
CLINICAL CHARACTERISTICS
7/15/21
Aeen FB, Pakzad R, Rad MG, et al. | Sci Rep
Aim: To determine the effects of PP on respiratory parameters and outcomes.
UPDATED
CANDIDATE THERAPEUTICS
7/15/21
Saragih ID, Advani S, Saragih IS, et al. | Geriatr Nurs
Aim: To study the impacts of frailty on COVID-19 outcomes.
UPDATED
CLINICAL CHARACTERISTICS
7/15/21
 | EUnetHTA
Aim: To review the evidence on the use of ivermectin for the treatment for COVID-19.
UPDATED
7/15/21
Yetmar Z, Chesdachai S, Kashour T, et al. | Open Forum Infect Dis
Aim: To examine the association between prior statin use and outcomes of patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/15/21
Low JM, Low YW, Zhong Y, et al. | Arch Dis Child Fetal Neonatal Ed
Aim: To review the evidence on the production of SARS-CoV-2 antibodies in human milk of individuals who had COVID-19, and antibodies' ability to neutralise SARS-CoV-2 infectivity.
UPDATED
INFECTION CONTROL
7/13/21
Pashazadeh Kan F, Raoofi S, et al. | J Affect Disord
Aim: To identify the individuals at higher risk of anxiety with a view to provide targeted mental health services during this outbreak.
UPDATED
MENTAL HEALTH
7/13/21
Viswanatha GL, Anjana Male CKVLSN, Shylaja H, et al. | Clin Exp Rheumatol
Aim: To evaluate the therapeutic benefits and safety of tocilizumab (TCZ) in treating severe coronavirus disease 2019 (COVID-19) and associated health complications.
UPDATED
CANDIDATE THERAPEUTICS
7/13/21
Akobeng AK, Grafton-Clarke C, Abdelgadir I, et al. | Frontline Gastroenterol
Aim: To summarise the published evidence on the gastrointestinal manifestations of COVID-19 in children and to determine the prevalence of gastrointestinal symptoms.
UPDATED
CLINICAL CHARACTERISTICS
7/13/21
Tegegne GT, Kefale B, Engidaw MT, et al. | Front Public Health
Aim: To investigate the level of KAP and associated factors among HCPs about COVID-19. 
UPDATED
INFECTION CONTROL
7/12/21
Zein AFMZ, Sulistiyana CS, Raffaelo WM, et al. | Diabetes Metab Syndr
Aim: To investigate the effect of ivermectin on mortality in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
7/12/21
Mansory E, Srigunapalan S, Lazo-Langner A | TH Open
Aim: To evaluate the epidemiology of VTE in hospitalized intensive care unit (ICU) and non-ICU patients.
UPDATED
CLINICAL CHARACTERISTICS
7/9/21
Schwartzberg L, Advani S, Clancy DC, et al. | Skin Health Dis
Aim: To summarize cutaneous manifestations associated with COVID?19.
UPDATED
CLINICAL CHARACTERISTICS
7/8/21
Najt P, Richards HL, Fortune D | Brain Behav Immun Health
Aim: To synthesise the potential evidence of the brain correlates of SARS-CoV-2.
UPDATED
CLINICAL CHARACTERISTICS
7/8/21
Gaythorpe K, Bhatia S, Mangal T, et al. | Sci Rep
Aim: To review the evidence on the susceptibility of children to SARS-CoV-2 infection, the severity and clinical outcomes in children with SARS-CoV-2 infection, and the transmissibility of SARS-CoV-2 by children.
UPDATED
CLINICAL CHARACTERISTICS
7/8/21
Ulloque-Badaracco JR, Salas-Tello WI, Al-Kassab-Cordova A, et al. | Int J Clin Pract
Aim: To evaluate the prognostic value of the NLR in patients diagnosed with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/8/21
Chisale MRO, Ramazanu S, Mwale SE, et al. | Rev Med Virol
Aim: To estimate the seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in residents of African countries and explore its associated factors.
UPDATED
CLINICAL CHARACTERISTICS
7/8/21
Egunsola O, Mastikhina L, Dowsett L, et al. | SPOR
Aim: To identify comparative observational studies and randomized controlled trials (RCTs) evaluating the effectiveness or efficacy of COVID-19 vaccination in reducing infection transmission, asymptomatic viral carriage and other proxies of possible transmission, such as cycle threshold (Ct) values and viral load.
UPDATED
7/7/21
Al-Amer R, Maneze D, Everett B, et al. | J Clin Nurs
Aim: To synthesise evidence regarding vaccination intention, identify factors contributing to vaccine hesitancy among healthcare professionals and the general populations globally.
UPDATED
INFECTION CONTROL
7/7/21
Pardhan S, Wood S, Vaughan M, et al. | Front Med
Aim: To examine the adjusted risk of COVID-19 related hospitalsation, intensive care unit (ICU) admission, and mortality in patients with vs. without asthma or COPD.
UPDATED
CLINICAL CHARACTERISTICS
7/6/21
Kremer D, Pieters TT, Verhaar MC, et al. | Am J Transplant
Aim: To assess all current evidence to provide an updated and robust insight in the clinical course and outcome of COVID-19 in KTR.
UPDATED
CLINICAL CHARACTERISTICS
7/6/21
Lassi ZS, Ana A, Das JK, et al. | J Glob Health
Aim: To determine the clinical presentation, risk factors, and pregnancy and perinatal outcomes in pregnant women with confirmed COVID-19 and identify if these are different based on COVID-19 severity.
UPDATED
CLINICAL CHARACTERISTICS
7/6/21
Franchini M, Prefumo F, Grisolia G, et al. | Viruses
Aim: To systematically examine the current evidence on the clinical use of convalescent plasma during pregnancy.
UPDATED
CANDIDATE THERAPEUTICS
7/6/21
Wibowo A, Pranata R, Lim MA, et al. | Int J Infect Dis
Aim: To compare the level of von Willebrand Factor (vWF) antigen in patients with poor outcome compared to those without. 
UPDATED
CLINICAL CHARACTERISTICS
7/6/21
Serrano-Ripoll MJ, Zamanillo-Campos R, Castro A, et al. | Actas Esp Psiquiatr
Aim: To examine the impact of the current health pandemic produced by COVID-19 on insomnia and sleep quality of health professionals, and to identify risk factors associated with insomnia.
UPDATED
MENTAL HEALTH
7/6/21
Romiti GF, Corica B, Lip GYH, et al. | J Clin Med
Aim: To investigate the epidemiology of AF in COVID-19 patients and its impact on all-cause mortality.
UPDATED
CANDIDATE THERAPEUTICS
7/6/21
Hao Q, Wang D, Xie M, et al. | Front Psychiatry
Aim: To review the evidence on the prevalence of mental health problems and risk factors among HCWs during the COVID-19 pandemic to identify at-risk HCWs and provide timely assistance and intervention.
UPDATED
MENTAL HEALTH
7/6/21
Bertuzzi V, Semonella M, Bruno D, et al. | Int J Environ Res Public Health
Aim: To review the evidence on the content and efficacy of the psychological support interventions in increasing mental health among healthcare providers and informal caregivers during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
7/6/21
Romero Starke K, Mauer R, Karskens E, et al. | Int J Environ Res Public Health
Aim: To collect evidence on the impact of temperature and humidity on COVID-19 mortality. 
UPDATED
CLINICAL CHARACTERISTICS
7/6/21
Beukes E, Ulep AJ, Eubank T, et al. | J Clin Med
Aim: To systematically review what has been published regarding tinnitus during the coronavirus disease 2019 (COVID-19) pandemic up to March 2021.
UPDATED
CLINICAL CHARACTERISTICS
7/6/21
Chigwedere OC, Sadath A, Kabir Z, et al. | Int J Environ Res Public Health
Aim: To examine the impact of epidemics and pandemics on the mental health of HCWs.
UPDATED
MENTAL HEALTH
7/6/21
Akbar MR, Pranata R, Wibowo A, et al. | Front Med
Aim: To assess the prognostic value of hyponatremia in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
7/2/21
Zein AFMZ, Sulistiyana CS, Khasanah U, et al. | Postgrad Med J
UPDATED
CLINICAL CHARACTERISTICS
7/1/21
Melo AKG, Milby KM, Caparroz ALMA, et al. | PLoS One
Aim: To describe the laboratory parameters and biomarkers of the cytokine storm syndrome associated with severe and fatal COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
7/1/21
Abeldaño Zuñiga RA, González-Villoria RAM, Elizondo MV, et al. | Ther Adv Respir Dis
Aim: To determine the clinical effectiveness of convalescent plasma employed in the treatment of hospitalized patients with diagnosis of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
7/1/21
Ciapponi A, Bardach A, Comande D, et al.  | PLoS One
Aim: To summarize the best evidence regarding the effect of COVID-19 on maternal and child health.
UPDATED
CLINICAL CHARACTERISTICS
7/1/21
Kula B, Clancy CJ, Nguyen MG, et al. | Lancet Microbe
Aim: To establish the prevalence of autopsy-proven tissue-invasive IMD and analyse individual-level data to assess potential risk factors.
UPDATED
CLINICAL CHARACTERISTICS
6/30/21
Chua EX, Zahir SMISM, Ng KT, et al. | J Clin Anesth
Aim: To investigate the effect of prone position on partial pressure of arterial oxygen/fraction of inspired oxygen (PaO2/FiO2) ratio.
UPDATED
CANDIDATE THERAPEUTICS
6/30/21
Sharma M, Aggarwal S, Madaan P, et al. | Sleep Med
Aim: To study the prevalence and pattern of sleep disturbances in children and adolescents during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
6/29/21
Crafa A, Cannarella R, Condorelli RA, et al. | EClinicalMedicine
Aim: To assess whether hypovitaminosis D is a risk factor for developing SARS-CoV-2 infection and whether it affects the worsening of the clinical course of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/29/21
Vindrola-Padros C, Singh KE, Sidhu MS, et al. | EClinicalMedicine
Aim: To analyse the implementation and impact of remote home monitoring models (virtual wards) during COVID-19, identifying their main components, processes of implementation, target patient populations, impact on outcomes, costs and lessons learnt.
UPDATED
INFECTION CONTROL
6/28/21
Kulkarni MS, Kakodkar P, Nesari TM, et al. | J Ayurveda Integr Med
Aim: To summarise the evidence from different systematic reviews of distinct yoga interventions used to improve mental health and recommend yoga practices for the same. 
UPDATED
MENTAL HEALTH
6/28/21
Lazarus G, Budiman RA, Rinaldi I, et al. | Cancer Immunol Immunother
Aim: To investigate the effects of ICI treatment on COVID-19 prognosis, including mortality, severity, and any other prognosis-related outcomes.
UPDATED
CANDIDATE THERAPEUTICS
6/28/21
Chow R, Im J, Chiu N, et al. | PLoS One
Aim: To conduct a systematic review and meta-analysis to report on adverse outcomes among COVID-19 patients by statin usage. 
UPDATED
CANDIDATE THERAPEUTICS
6/25/21
Drury J, Mao G, John A, et al. | BMC Public Health
Aim: To describe public attitudes towards certification, and its possible impact on uptake of testing and vaccination, protective behaviours, and crime.
UPDATED
INFECTION CONTROL
6/25/21
Ren X, Wang X, Ge Z, et al. | Int J Immunopathol Pharmacol
Aim: To examine immune function status-related manifestations and laboratory indicators of COVID-19 patients with recurrent virus PCR positivity.
UPDATED
CLINICAL CHARACTERISTICS
6/25/21
Nawangsih EN, Kusmala YY, Rakhmat II, et al. | Int Immunopharmacol
Aim: To evaluate the effect of colchicine administration on mortality in patients with COVID-19 and factors affecting the association.
UPDATED
CANDIDATE THERAPEUTICS
6/25/21
Bobrovitz N, Arora R, Cao C, et al.  | PLoS ONE
Aim: To synthesize seroprevalence data to better estimate the burden of SARS-CoV-2 infection, identify high-risk groups, and inform public health decision making.
UPDATED
CLINICAL CHARACTERISTICS
6/25/21
Zinellu A, Mangoni A | Front Immunol
Aim: To investigate possible differences in the serum concentrations of two routinely measured complement components, C3 and C4, in COVID-19 patients with different severity and survival status.
UPDATED
CLINICAL CHARACTERISTICS
6/25/21
Yamamoto S, Saito M, Tamura A, et al. | PLoS One
Aim: To evaluate existing evidence on the association between the microbiome and COVID-19 in humans and summarize this data in the pandemic era.
UPDATED
CLINICAL CHARACTERISTICS
6/25/21
Pal R, Banerjee M, Bhadada SK, et al. | J Endocrinol Invest
Aim: To provide a precise summary and collate the hitherto available clinical evidence on the effect of vitamin D supplementation on clinical outcomes in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
6/23/21
Tripathy SK, Varghese P, Panigrahi S, et al. | Chin J Traumatol
Aim: To evaluate the 30-day mortality and complications in COVID-19 + and COVID-19 ? patients with hip fractures.
UPDATED
CLINICAL CHARACTERISTICS
6/21/21
Locquet M, Diep AN, Beaudart C, et al. | Arch Public Health
Aim: To identify, compare, and evaluate performances of prediction models for the diagnosis of COVID-19 in adult patients in a health care setting.
UPDATED
DIAGNOSTICS
6/18/21
Adibi A, Golitaleb M, Farrahi-Ashtiani I, et al. | Front Psychiatry
Aim: To investigate GAD's prevalence among HCWs during the COVID-19 pandemic by systematic review and meta-analysis.
UPDATED
MENTAL HEALTH
6/17/21
Nopsopon T, Kittrakulrat J, Takkavatakarn K, et al. | PLoS Negl Trop Dis
Aim: To evaluate the prevalence and case fatality rate of COVID-19 in patients with ESRD with RRT.
UPDATED
CLINICAL CHARACTERISTICS
6/17/21
Yusuf F, Fahriani M, Mamada SS, et al. | F1000Res
Aim: To determine the cumulative prevalence of prolonged gastrointestinal (GI) symptoms, including nausea, vomiting, diarrhea, lack of appetite, abdominal pain, and dysgeusia, in survivors of both mild and severe COVID-19 worldwide and to discuss the potential pathogenesis.  
UPDATED
CLINICAL CHARACTERISTICS
6/17/21
Alimoradi Z, Brostrom A, Tsang HWH, et al. | EClinicalMedicine
Aim: To estimate the magnitude of sleep problems during the COVID-19 pandemic and its relationship with psychological distress.
UPDATED
MENTAL HEALTH
6/16/21
Taheri L, Gheiasi SF, Taher M, et al. | Compr Child Adolesc Nurs
Aim: To identify and summarize the existing evidence on clinical characteristics of COVID-19 in pediatric patients. 
UPDATED
CLINICAL CHARACTERISTICS
6/16/21
Ramanathan K, Shekar K, Ling RR, et al. | Crit Care
Aim: To summarise outcome data during the first year of the pandemic and identify risk factors for an unfavourable outcomes in order to guide clinical decision-making and further research.
UPDATED
CLINICAL CHARACTERISTICS
6/16/21
Maidment I, Young E, MacPhee M, et al. | BMJ Open
Aim: To understand how community pharmacy can most effectively deliver essential and advanced services, with a focus on vaccination, during the pandemic and in the future.
UPDATED
INFECTION CONTROL
6/14/21
Chan KW, Yu KY, Lee PW, et al. | Front Med
Aim: To assess the association between AKI, mortality, underlying non-communicable diseases, and clinical risk factors.
UPDATED
CLINICAL CHARACTERISTICS
6/14/21
Ibrahimi N, Delaunay-Moisan A, Hill C, et al. | PLoS One
Aim: To compare saliva and nasopharyngeal/oropharyngeal samples for the detection of SARS-CoV-2.
UPDATED
DIAGNOSTICS
6/11/21
Akbar M, Pranata R, Wibowo A, et al | Eur Rev Med Pharmacol Sci
Aim: To evaluate the association between the prealbumin and severity and mortality in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/10/21
Hughes MC, Liu Y, Baumbach A | Gerontol Geriatr Med
Aim: To examine the current literature on the impact of COVID-19 on the health and well-being of informal caregivers for people with dementia. 
UPDATED
MENTAL HEALTH
6/10/21
Zein AFMZ, Sulistiyana CS, Raffaello WM, et al. | Postgrad Med J
Aim: To evaluate the effect of sofosbuvir/daclatasvir (SOF/DCV) on mortality, the need for intensive care unit (ICU) admission or invasive mechanical ventilation (IMV) and clinical recovery in patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/9/21
Asiimwe IG, Pushpakom S, Turner R, et al | Br J Clin Pharmacol
Aim: To continually evaluate the rapidly evolving evidence base on the role of cardiovascular drugs in COVID-19 clinical outcomes (susceptibility to infection, hospitalization, hospitalization length, disease severity, and all-cause mortality).
UPDATED
CLINICAL CHARACTERISTICS
6/9/21
Amani B, Khanijahani A, Amani B | Sci Rep
Aim: To examine the efficacy and safety of HCQ in addition to standard of care (SOC) in COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/9/21
Matli K, Farah R, Maalouf M, et al. | Open Heart
Aim: To highlight the role of thrombosis in COVID-19 and provide new insights on the use of antithrombotic therapy in its management. 
UPDATED
CANDIDATE THERAPEUTICS
6/8/21
Yang J, D'souza R, Kharrat A, et al. | Acta Obstet Gynecol Scand
Aim: To conduct a living systematic review and meta-analyses of studies reporting pregnancy and neonatal outcomes by comparing the pandemic and pre-pandemic periods.
UPDATED
CLINICAL CHARACTERISTICS
6/8/21
Sarkar S, Kannan S, Khanna P, et al. | Rev Med Virol
Aim: To explore the utility of RDW in the prognosis of COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
6/7/21
Liu X, Wang H, Shi S, et al. | Postgrad Med J
Aim: To evaluate the association between IL-6 and severe disease and mortality in COVID-19 disease.
UPDATED
CLINICAL CHARACTERISTICS
6/7/21
Guerrero JI, Barragan LA, Martinez JD, et al. | BMC Infect Dis
Aim: To describe the features of the central and peripheral nervous system involvement by COVID-19 in terms of pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings.
UPDATED
CLINICAL CHARACTERISTICS
6/7/21
Nascimento I, O Mathuna DP, von Groote TC, et al. | BMC Infect Med
Aim: To collate and summarize all published systematic reviews on the coronavirus disease (COVID-19).
UPDATED
6/7/21
Messina A, Sanfilippo F, Milani A, et al. | J Crit Care
Aim: To summarise the current knowledge regarding cardiac dysfunction in COVID-19 as assessed by echocardiography, both in ICU and non-ICU subjects.
UPDATED
CLINICAL CHARACTERISTICS
6/7/21
Seidu S, Kunutsor SK, Cos X, et al. | Prim Care Diabetes
Aim: To assess the indirect impact of the COVID-19 pandemic on hospitalisations for cardiovascular diseases and their management.
UPDATED
INFECTION CONTROL
6/7/21
Rogers JP, Watson CJ, Badenoch J, et al. | J Neurol Neurosurg Psychiatry
Aim: To describe the characteristics of the early literature and estimate point prevalences for neurological and neuropsychiatric manifestations.
UPDATED
CLINICAL CHARACTERISTICS
6/7/21
Ao G, Wang Y, Qi X, et al. | Transplant Rev
Aim: To investigate the association between severe or fatal COVID-19 and SOT.
UPDATED
6/7/21
Elsayed HH, Hassaballa AS, Ahmed TA, et al. | PLoS One
Aim: To review the evidence on IMV for COVID-associated ARDS to study its outcome among different countries.
UPDATED
CANDIDATE THERAPEUTICS
6/3/21
Jimenez-Cebrian AM, Castro-Mendez A, Garcia-Podadera B, et a;/ | J Clin Med
Aim: To analyze and synthesize the published reviews on manifestations of COVID-19 at the foot level. 
UPDATED
CLINICAL CHARACTERISTICS
6/3/21
Wang R, Liu M, Liu J | Vaccines
Aim: To assess the association between influenza vaccination and SARS-CoV-2 infection and clinical outcomes.
UPDATED
CLINICAL CHARACTERISTICS
6/3/21
Khan DSA, Pirzada AN, Ali A, et al. | Int J Environ Res Public Health
Aim: To investigate the differences in clinical presentation, management, and prognosis of COVID-19 infection in pregnant and non-pregnant women.
UPDATED
CLINICAL CHARACTERISTICS
6/3/21
Stroehlein JK, Wallqvist J, Iannizzi C, et al.  | Cochrane Database Syst Rev
Aim: To assess whether vitamin D supplementation is effective and safe for the treatment of COVID?19 in comparison to an active comparator, placebo, or standard of care alone, and to maintain the currency of the evidence, using a living systematic review approach.
UPDATED
CANDIDATE THERAPEUTICS
6/2/21
Wilt T, Kaka AS, MacDonald R, et al. | VA Evidence Synthesis Program
Aim: To assess the clinical effectiveness and harms of remdesivir in hospitalized adults with COVID-19.
UPDATED
VA ESP
6/2/21
Wang MX, Gwee SXW, Pang J | Nutrients
Aim: To systematically assess the associations between micronutrient supplementation or deficiency, with novel coronavirus incidence and disease severity.
UPDATED
CLINICAL CHARACTERISTICS
6/1/21
Grove A, Osokogu O, Al-Khudairy L, et al. | BMJ Open
Aim: To systemically review and critically appraise published studies of the association between vitamin D supplementation or serum vitamin D level and susceptibility to SARS-CoV-2 infection or COVID-19, including clinical course, morbidity and mortality outcomes.
UPDATED
CLINICAL CHARACTERISTICS
6/1/21
Ayouni I, Maatoug J, Dhouib W, et al.  | BMC Public Health
Aim: To evaluate the implemented public health interventions to control the spread of the outbreak of COVID-19.
UPDATED
INFECTION CONTROL
6/1/21
Chou R, Dana T, Buckley D, et al. | Ann Intern Med
Aim: To examine the burden of SARS-CoV-2, SARS-CoV-1, and Middle Eastern respiratory syndrome (MERS)-CoV on HCWs and risk factors for infection, using rapid and living review methods.
UPDATED
WHO COLLABORATIVE
6/1/21
Lee Y, Lui LMW, Chen-Li D, et al. | J Affect Disord
Aim: To evaluate the impact of the COVID-19 pandemic and government response on measures of depressive symptom presence and severity based on published studies.
UPDATED
MENTAL HEALTH
6/1/21
Kaur H, Thakur JS, Paika R, et al. | Asian Pac J Cancer Prev
Aim: To explore the prevalence of comorbidities among cancer patients with SARS CoV-2 infection and their impact on mortality.
UPDATED
CLINICAL CHARACTERISTICS
6/1/21
Muehlschlegel P, Parkinson E, Chan RYL, et al. | J Glob Health
Aim: To comprehensively evaluate biopsychosocial consequences after lockdown measures are lifted and identify strategies to successfully negotiate the transition out of COVID-19 related lockdowns.
UPDATED
MENTAL HEALTH
6/1/21
Amani B, Khanijahani A, Amani B, et al. | J Pharm Pharm Sci
Aim: To provide the latest evidence on the efficacy and safety of lopinavir/ritonavir compared to other treatment options for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/1/21
Zawawi A, Naser AY, Alwafi H, et al. | Front Immunol
Aim: To evaluate the inflammatory cytokines profile associated with severe human coronavirus diseases, including three stains: MERS-CoV, SARS-CoV SARS-CoV-2, in severe patients.
UPDATED
CLINICAL CHARACTERISTICS
5/28/21
Staibano P, Levin M, McHugh T, et al. | JAMA Otolaryngol Head Neck Surg
Aim: To evaluate the association of tracheostomy with COVID-19 patient outcomes and the risk of SARS-CoV-2 transmission among health care professionals (HCPs).
UPDATED
INFECTION CONTROL
5/28/21
Iqbal FM, Lam K, Sounderajah V, et al. | EClinicalMedicine
Aim: To characterise the clinical features between acute and chronic post-COVID syndrome.
UPDATED
CLINICAL CHARACTERISTICS
5/28/21
Sahilu T, Sheleme T, Melaku T | Interdiscip Perspect Infect Dis
Aim: To summarize the current evidence of the severity and mortality associated with steroid therapy for patients with COVID-19. 
UPDATED
CANDIDATE THERAPEUTICS
5/24/21
Mangkuliguna G, Glendardi G, Susanto N, et al. | Tuberc Respir Dis
Aim: To investigate the efficacy and safety of Azithromycin in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/24/21
Abate SM, Chekole YA, Estifanos MB, et al. | Clin Nutr ESPEN
Aim: To investigate the prevalence and outcome of malnutrition among patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/24/21
Li W, Zhang H, Zhang C, et al. | Front Psychol
Aim: To review the evidence on the prevalence of different psychological states during the early stage of the COVID-19 epidemic in China.
UPDATED
MENTAL HEALTH
5/24/21
Snow TAC, Saleem N, Ambler G, et al. | Intensive Care Med
Aim: To ascertain the benefit of IL-6 blockade with tocilizumab for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
5/21/21
Singhal S, Kumar P, Singh S, et al. | BMC Geriatr
Aim: To review the evidence on the clinical characteristics of older COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/21/21
Bzeizi K, Abdulia M, Mohammed N, et al. | Sci Rep
Aim: To assess the available evidence on the clinical effects of SARS-CoV-2 on liver function laboratory tests and coagulation profile in affected individuals. 
UPDATED
CLINICAL CHARACTERISTICS
5/21/21
Xiong X, Chi J, Gao Q | Thromb J
Aim: To determine the prevalence and risk factors of thrombotic events on COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/20/21
Wang J, Kaperak C, Sato T, et al. | J Investig Med
Aim: To identify cases infected with different genetic strains of SARS-CoV-2 confirmed by polymerase-chain reaction and viral genome sequencing.
UPDATED
DIAGNOSTICS
5/20/21
Pannone G, Caponio VCA, De Stefano IS, et al. | Infect Agent Cancer
Aim: To summarize lung histopathological characteristics of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/17/21
Nochaiwong S, Ruengorn C, Thavorn K, et al. | Sci Rep
Aim: To provide a contemporary global prevalence of mental health issues among the general population amid the coronavirus disease-2019 (COVID-19) pandemic. 
UPDATED
MENTAL HEALTH
5/17/21
Lei H, Yang Y, Zhou W, et al. | Lung Cancer
Aim: To provide precise estimates of the mortality rate of COVID-19 patients with lung cancer and other tumors.
UPDATED
5/17/21
Shao SC, Lai CC, Chen YH, et al. | Age Aging
Aim: To summarize the evidence on prevalence, incidence and mortality of delirium in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
5/14/21
De Crescenzo F, Amato L, Cruciani F, et al. | Front Pharmacol
Aim: To assess the comparative efficacy and safety of pharmacological interventions for COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
5/14/21
Siow I, Lee KS, Zhang JJY, et al. | Eur J Neurol
Aim: To describe the incidence, clinical course and outcomes of patients who suffer from encephalitis as a complication of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/14/21
Chambergo-Michilot D, Barros-Sevillano S, Rivera-Torrejon O, et al. | Eur J Neurol
Aim: To systematically review the factors associated with COVID-19 in people with PD.
UPDATED
CLINICAL CHARACTERISTICS
5/14/21
Heath L, Carey M, Lowney AC, et al.  | Palliat Med
Aim: To determine the dose ranges of pharmacological interventions commonly used to manage symptoms in adult patients dying of COVID-19, establish how effectiveness of these interventions was measured, and whether the pharmacological interventions were effective.
UPDATED
CANDIDATE THERAPEUTICS
5/14/21
Paternoster G, Bertini P, Innelli P, et al. | J Cardiothorac Vasc Anesth
Aim: To describe the features of right ventricular impairment and pulmonary hypertension in coronavirus disease (COVID-19) and assess their effect on mortality.
UPDATED
CLINICAL CHARACTERISTICS
5/13/21
Kang S, Gong X, Yuan Y | Epidemiol Infect
Aim: To systematically assess the association between smoking and cardiovascular disease and disease progression among novel coronavirus pneumonia (COVID-19) cases.
UPDATED
CLINICAL CHARACTERISTICS
5/13/21
Ahammed T, Anjum A, Rahman MM, et al. | Health Sci Rep
Aim: To estimate the R0 and CFR of COVID-19 and assess whether the parameters vary in different regions of the world.
UPDATED
INFECTION CONTROL
5/13/21
Martimbianco ALC, Pacheco RL, Bagattini AM, et al. | Int J Clin Pract
Aim: To identify, systematically evaluate and summarise the best available evidence on the frequency of long COVID (post-acute COVID-19 syndrome), its clinical manifestations and the criteria used for diagnosis.
UPDATED
LONG COVID
5/11/21
Wijaya I, Andhika R, Huang I, et al. | Clin Epidemiol Glob Health
Aim: To assess the efficacy of JAK inhibitors in terms of clinical outcome, including mortality, clinical improvement, and clinical deterioration among hospitalized COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/10/21
Turner S, Botero-Tovar N, Herrera MA, et al. | Implement Sci
Aim: To depict the experiences and perceptions of organisations and actors at multiple levels of health systems internationally in responding to COVID-19.
UPDATED
INFECTION CONTROL
5/7/21
Gulsen A, Konig I, Jappe U, et al. | Respirology
Aim: To examine in detail whether the underlying chronic obstructive pulmonary diseases (COPD), asthma and chronic respiratory diseases (CRDs) were associated with an increased risk of more severe COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
5/7/21
Dembrovszky F, Váncsa S, Farkas N, et al. | Viruses
Aim: To evaluate which prognostic factors may impact repeated SARS-CoV-2 positivity (RSP) and their association with immunoglobulin detectability among recovered patients. 
UPDATED
CLINICAL CHARACTERISTICS
5/7/21
Cosco TD, Best J, Davis D, et al. | Age Aging
Aim: To quantify the association between frailty and COVID-19 in relation to mortality in hospitalised patients.
UPDATED
CLINICAL CHARACTERISTICS
5/4/21
Dos Santos ACM, Dos Santos BRC, Dos Santos BB, et al. | Infect Genet Evol
Aim: to review the effect of single nucleotide polymorphisms in the development of severe acute respiratory syndrome (SARS).
UPDATED
CLINICAL CHARACTERISTICS
5/4/21
Liang M, Luo N, Chen M, et al. | Infect Dis Ther
Aim: To investigate the prevalence and mortality in PLWHA co-infected with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
5/3/21
Neira C, Godinho R, Rincon F, et al. | Nutrients
Aim: To evaluate the current evidence about the impact that preventive measures of physical contact restriction causes in healthy nutrition.
UPDATED
5/3/21
Tleyjeh IM, Kashour Z, Riaz M, et al. | Clin Microbiol Infect
Aim: To perform a living systematic review of the literature about the efficacy and toxicity of the IL-6 receptor antagonist, tocilizumab, in COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/3/21
La Verde M, Riemma G, Torella M, et al. | Int J Gynaecol Obstet
Aim: To evaluate the characteristics of pregnant women deceased due to COVID-19.
UPDATED
5/3/21
Dramé M, Cofais C, Hentzien M, et al. | Nutrients
Aim: To identify and synthesize the best available evidence on the association between vitamin D level and risk of COVID-19, adverse outcomes and possible benefits of supplementation aged 60 years or over.
UPDATED
5/1/21
Tharmarajah E, Buazon A, Patel V, et al. | J Infect
Aim: To assess the impact of IL-6 inhibition on mortality in the treatment of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/29/21
Choudary MC, Crain CR, Qiu X, et al.  | Clin Infect Dis
Aim: To characterize the hallmarks of reinfecting sequences and the rate of viral evolution in persistent infection.
UPDATED
CLINICAL CHARACTERISTICS
4/29/21
Hammond A, Khalid T, Thornton HV, et al. | PLoS One
Aim: To investigate whether modern portable, commercially available air filters reduce the incidence of respiratory infections and/or remove bacteria and viruses from indoor air.
UPDATED
INFECTION CONTROL
4/28/21
Hayward SE, Deal A, Cheng C, et al. | J Migr Health
Aim: To assess clinical outcomes of COVID-19 in migrant populations (cases, hospitalisations, deaths), indirect health and social impacts, and to determine key risk factors.
UPDATED
CLINICAL CHARACTERISTICS
4/28/21
Bartoszko JJ, Siemieniuk RAC, Kum E, et al. | BMJ
Aim: To determine and compare the effects of drug prophylaxis on severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (covid-19).
UPDATED
4/27/21
Sheikh AB, Chourasia PK, Javed N, et al. | J Neuroimmunol
Aim: To determine demographic characteristics, clinical features, lab evaluation, management and complications of the studies focusing on Guillain-Barre syndrome (GBS) as a sequele of novel coronavirus (COVID-19) infection.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Patralekh MK, Jain V, Iyengar K, et al.  | J Clin Orthop Trauma
Aim: To evaluate the impact of COVID-19 on patients with PFF and assessed associated mortality.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Wu Y, Li H, Zhang Z, et al. | Ann Palliat Med
Aim: To evaluate the in-hospital mortality and risk factors of death in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/27/21
Mackey K, Kansagara D, Vela K | Ann Intern Med
Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.
UPDATED
WHO COLLABORATIVE
VA ESP
4/26/21
Varghese A, George G, Kondaguli SV, et al. | J Glob Health
Aim: To explore the prevalence and determinants of mental health outcomes (anxiety, stress, depression, PTSD, insomnia) among nurses across the globe due to the COVID-19.
UPDATED
MENTAL HEALTH
4/26/21
Muller AE, Himmels JPW, Van de Velde S | BMC Med Res Methodol
Aim: To review the diagnostic tests developed to assess or diagnose COVID-19-related fear or phobia.
UPDATED
MENTAL HEALTH
4/16/21
Damiano RF, Di Santi D, Beach S, et al. | Braz J Psychiatry
Aim: To review the most common mental health strategies aimed at alleviating and/or preventing mental health problems in individuals during the coronavirus disease 2019 (COVID-19) and other coronavirus pandemics.
UPDATED
MENTAL HEALTH
4/14/21
Mondal R, Deb S, Shome G, et al. | Mult Scler Relat Disord
Aim: To summarize so far available pieces of evidence documenting de novo novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) mediated spinal cord demyelinating diseases.
UPDATED
CLINICAL CHARACTERISTICS
4/14/21
Flook M, Jackson C, Vasileiou E, et al. | BMC Infect Dis
Aim: To review the evidence on the risk factors for severity, disease, and mortality for COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Handayani DR, Juliastuti H, Nawangsih EN, et al. | Obes Med
Aim: To assess the prognostic value of fasting hyperglycemia in patients with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/13/21
Pranata R, Huang I, Lawrensia S, et al. | Pharmacol Rep
Aim: To address the current interest of whether the administration of PPI could increase the susceptibility and risk of poor outcome in COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/12/21
Phiri P, Ramakrishnan R, Rathod S, et al. | EClinicalMedicine
Aim: To review the evidence on the mental health impacts of the COVID-19 pandemic on healthcare professionals, patients, and the general public.
UPDATED
MENTAL HEALTH
4/12/21
Meza N, Perez-Bracchiglione J, Perez I, et al. | Medwave
Aim: To provide a timely, rigorous, and continuously updated summary of the evidence available on the role of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) in the treatment of patients with COVID-19.
UPDATED
4/12/21
Barboza JJ, Chambergo-Michilot D, Velasquez-Sotomayor M, et al. | Travel Med Infect Dis
Aim: To describe the assessment and treatment of asymptomatic infection in patients with a confirmed diagnosis of COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/12/21
Tomfohr-Madsen L, Racine N, Giesbrecht GF, et al.  | Psychiatry Res
Aim: To analyze the worldwide prevalence of depression and anxiety among pregnant women during the COVID-19 pandemic.
UPDATED
MENTAL HEALTH
4/12/21
Rakhmat II, Kusmala YY, Handayani DR, et al. | Diabetes Metab Syndr
Aim: To synthesize evidence on dipeptidyl peptidase-4 (DPP-4) inhibitor and mortality in COVID-19 patients and factors affecting it.
UPDATED
CANDIDATE THERAPEUTICS
4/12/21
Qiu D, Li Y, Li L, et al. | Eur Psychiatry
Aim: To examine the pooled prevalence of post-traumatic stress symptoms among people exposed to the trauma resulting from COVID-19 outbreak.
UPDATED
MENTAL HEALTH
4/12/21
Palaiodimou L, Stefanou MI, Katsanos AH, et al. | Eur J Neurol
Aim: To critically appraise the published literature related to GBSs and COVID-19, and evaluate prevalence, clinical features and outcomes of GBSs in pateints with COVID-19 compared to non-COVID-19 contemporary or historical controls.
UPDATED
CLINICAL CHARACTERISTICS
4/12/21
Dhouib W, Maatoug J, Ayouni I, et al. | Syst Rev
Aim: To identify studies that recruited symptomatic patients, regardless of sex or age diagnosed with COVID-19, and calculated or estimated the incubation period between December 2019 and December 2020.
UPDATED
CLINICAL CHARACTERISTICS
4/9/21
Morales-Cane I, del Rocio Valverde-Leon M, Gonzalez-Gancedo J, et al. | Eur Rev Med Pharmacol Sci
Aim: To synthesize and analyze the scientific publications related to ventilatory therapies used in patients with COVID-19 in Intensive Care Units (ICUs), the parameters of invasive mechanical ventilation prescribed for these patients, and the clinical characteristics of patients admitted to the ICU.
UPDATED
CANDIDATE THERAPEUTICS
4/8/21
Mutiawati E, Fahriani M, Mamada SS, et al. | F1000Res
Aim: To determine the global prevalence of anosmia and dysgeusia in coronavirus disease 2019 (COVID-19) patients and to assess their association with severity and mortality of COVID-19. 
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Saragih ID, Saragih IS, Batubara SO, et al. | Geriatr Nurs
Aim: To systematically examine the association between dementia and mortality among older adults with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Rezaei S, Fatemi B, Majd ZK, et al. | Expert Rev Clin Immunol
Aim: To combine the results of clinical studies of different designs to investigate the efficacy and safety of tocilizumab in severely-to-critically ill COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
4/8/21
Islam MA, Kundu S, Alam SS, et al. | PLoS One
Aim: To conduct a systematic review and meta-analysis to estimate the overall pooled prevalence of fever and chills in addition to fever characteristics (low, medium, and high temperature) in both adult and paediatric COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/8/21
Sriharan A, Ratnapalan S, Tricco AC, et al. | BMJ Open
Aim: To identify the causes of occupational stress and burnout in women in medicine, nursing, and other health professions during the COVID-19 pandemic and interventions that can support female health professionals deal with this crisis through a rapid review.
UPDATED
MENTAL HEALTH
4/7/21
Saha S, Al-Rifai RH, Saha S | J Diabetes Metab Disord
Aim: To quantify the overall and subgroup weighted prevalence of mortality among diabetic (primary outcome) and non-diabetic (secondary outcome) and the weighted prevalence of DM (secondary outcome), in hospitalized COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
4/6/21
Hoang T | Ann Glob Health
Aim: To examine the characteristics of repositive COVID-19 cases.
UPDATED
CLINICAL CHARACTERISTICS
4/6/21
Yan H, Ding Y, Guo W | Psychosom Med
Aim: To quantify the prevalence of the adverse mental health outcomes in medical staff working in the hospital settings during the COVID-19 pandemic and explore the relative distribution of anxiety and depressive symptoms.
UPDATED
MENTAL HEALTH
4/6/21
Kollias A, Kyrikoulis KG, Lagou S, et al. | Vasc Med
Aim: To review the current evidence regarding the prevalence of VTE in patients with COVID-19 screened/assessed with lower limb ultrasonography or computed tomography pulmonary angiography.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Lee KW, Yap SF, Ngeow YF, et al.  | Int J Environ Res Public Health
Aim: To determine the epidemiological characteristics, clinical signs and symptoms, blood parameters, and clinical outcomes among PLHIV who contracted COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Meherali S, Punjani N, Louie-Poon S, et al. | Int J Environ Res Public Health
Aim: To identify the impact of the pandemic on children's and adolescent's mental health and to evaluate the effectiveness of different interventions employed during previous and the current pandemic to promote children's and adolescents' mental health. 
UPDATED
MENTAL HEALTH
4/5/21
Li YC, Lai T, Lin S, et al. | Ther Adv Chronic Dis
Aim: To evaluate the influence of pre-existing CKD on risks of all-cause mortality, hospitalization, and critically ill condition among patients with COVID-19 infection.
UPDATED
4/5/21
Váncsa S, Dembrovsky F, Farkas N, et al.  | Viruses
Aim: To evaluate the clinical significance of repeatedly positive testing after coronavirus disease 2019 (COVID-19) recovery.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Lin W, Hung S, Lai C, et al. | Int Immunopharmacol
Aim: To investigate the clinical efficacy and safety of tocilizumab for treating patients with COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
4/5/21
Zhao Y, Jin Y, Rao W, et al. | J Affect Disord
Aim: To compare the prevalence of psychiatric comorbidities in all subpopulations during the SARS and COVID-19 epidemics.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Marchi R, Sugita B, Centa A, et al. | Infect Genet Evol
Aim: To describe the role, function, and association of miRNAs in SARS-CoV-2 human infection and COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
4/5/21
Wang Z, Wang Y, Yang Z, et al. | Int J Infect Dis
Aim: To appraise the quality and availability of guidelines stated and whether non-invasive ventilation in the early stage of the pandemic is of importance.
UPDATED
CANDIDATE THERAPEUTICS
4/5/21
Gisondi P, Di Leo S, Bellinato F, et al. | Dermatol Ther
Aim: To systematically review the studies reporting the time of onset of selected skin lesions with respect to the reported onset of the COVID-19 core symptoms.
UPDATED
CLINICAL CHARACTERISTICS
4/2/21
Jacob S, Hammed A, Lam V, et al. | ANZ J Surg
Aim: To assess the consistency of national and international surgical society recommendations regarding the choice of surgical approach; assess the quality of evidence of viral emission in surgical aerosol; and assess the quality of evidence comparing aerosol generation by different surgical energy devices.
UPDATED
INFECTION CONTROL
4/2/21
Ayers CK, Kondo KK, Williams BE, et al. | J Gen Intern Med
Aim: To understand disparities in H1N1 vaccine uptake by race/ethnicity, socioeconomic status (SES), rural/urban residence, population density, and disability status, and factors associated with unequal uptake, as well as the benefits and harms of interventions designed to attenuate inequities in H1N1 vaccine uptake
UPDATED
VA ESP
INFECTION CONTROL
4/2/21
Abdelrahman Z, Liu Q, Jiang S, et al. | Front Pharmacol
Aim: To estimate the impact of current treatments on the efficacy and safety of COVID-19 by a meta-analysis.
UPDATED
CANDIDATE THERAPEUTICS
4/2/21
Upshaw TL, Brown C, Smith R, et al. | PLoS One
Aim: To review the early reports on the social determinants of COVID-19 infection, health service use and health outcomes.
UPDATED
INFECTION CONTROL
4/2/21
Zhang L, Hou J, Ma FZ, et al. | Arch Virol
Aim: To identify risk factors for COVID-19 severity and mortality. 
UPDATED
CLINICAL CHARACTERISTICS
4/1/21
Calzetta L, Ritondo BL, Coppola A, et al. | Vaccines
Aim: To identify the factors that may potentially influence the clinical efficacy of COVID-19 vaccines for which data from Phase III trials are currently available.
UPDATED
INFECTION CONTROL
4/1/21
Yassin A, Nawaiseh M, Shaban A, et al.  | BMC Neurol
Aim: To address the neurological aspects of COVID-19 including NM, NC, and ND findings.
UPDATED
CLINICAL CHARACTERISTICS
3/31/21
Kunzler AM, Rothke N, Gunthner L, et al. | Global Health
Aim: To assess its impact on mental health during the early phase by comparing pandemic with prepandemic data and to identify potential risk and protective factors.
UPDATED
MENTAL HEALTH
3/30/21
Papadopoulos V, Koutroulos MV, Zikoudi DG, et al. | Diabetol Int
Aim: To examine diabetes-related acute metabolic emergencies in COVID-19 patients
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Peter HJ, Vancsa S, Ocskay K, et al. | Front Med
Aim: To evaluate if MAFLD or NAFLD are associated with a more severe disease course of COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
3/30/21
Sucha D, van Hamersvelt RW, van den Hoven AF, et al. | Radiol Cardiothorac Imaging
Aim: To synthesize the literature on diagnostic test accuracy of chest radiography, CT, and US for the diagnosis of coronavirus disease 2019 (COVID-19) in patients suspected of having COVID-19 in a hospital setting and evaluate the extent of suboptimal reporting and risk of bias.
UPDATED
DIAGNOSTICS
3/30/21