3/2/22

Major Update 2: Remdesivir for Adults With COVID-19: A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points     

Kaka AS, MacDonald R, Linskens EJ, et al. | Ann Intern Med

Aim: To evaluate the effectiveness and harms of remdesivir for COVID-19.

2/16/22

Mental health outcomes of adults hospitalized for COVID-19: A systematic review   

Veazie S, LaFavor B, Vela K, et al.  | J Affect Disord Rep

Aim: To compare the prevalence of mental health disorders among adults who have been hospitalized for COVID-19 to relevant comparison groups, assess whether the prevalence of mental health disorders varies by patient and disease characteristics, and ascertain mental health care utilization and resource needs for adults following hospitalization for COVID-19.

1/13/22

Preventing Unequal Health Outcomes in COVID-19: A Systematic Review of Past Interventions   

Williams BE, Kondo KK, Ayers CK, et al. | Health Equity

Aim: To identify interventions that have effectively reduced disparities in health outcomes in infectious disease outbreaks or natural disasters in the United States and understand whether such interventions could be applied to reduce health disparities in the current COVID-19 pandemic.

6/2/21

COVID-19: Remdesivir for adults - A Living Review   

Wilt T, Kaka AS, MacDonald R, et al. | VA Evidence Synthesis Program

Aim: To assess the clinical effectiveness and harms of remdesivir in hospitalized adults with COVID-19.

4/27/21

Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults: A Living Systematic Review     

Mackey K, Kansagara D, Vela K | Ann Intern Med

Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.

4/2/21

Disparities in H1N1 Vaccination Rates: a Systematic Review and Evidence Synthesis to Inform COVID-19 Vaccination Efforts   

Ayers CK, Kondo KK, Williams BE, et al. | J Gen Intern Med

Aim: To understand disparities in H1N1 vaccine uptake by race/ethnicity, socioeconomic status (SES), rural/urban residence, population density, and disability status, and factors associated with unequal uptake, as well as the benefits and harms of interventions designed to attenuate inequities in H1N1 vaccine uptake

1/15/21

LIVING RAPID REVIEW: Risk of transmitting COVID-19 during nebulizer treatment   

Goldstein KM, Ghadimi K, Mystakelis H, et al. | VA Evidence Synthesis Program

Aim: To review the evidence on the risk of transmitting SARS-CoV-2, SARS, MERS, and influenza with administration of drugs via nebulizer

8/18/20

Evidence Brief: COVID-19 post-acute care major organ damage 

Greer N, Wilt T, Duan-Porter D, et al  | VA Evidence Synthesis Program

7/10/20

STUDY REVIEW: Famotidine use is associated with improved clinical outcomes in hospitalized COVID-19 patients: A propensity score matched retrospective cohort study by Daniel E. Freedberg et al. 

Lewis J, Mackey K | VA Evidence Synthesis Program

Aim: To critically appraise the identified study and provide additional context for study findings.

6/26/20

RAPID RESPONSE: Corticosteroid therapy for COVID-19 infection [no longer being updated] 

Helfand M | VA Evidence Synthesis Program

Aim: To review the evidence for using corticosteroids to treat acute respiratory distress syndrome in patients with COVID-19.

6/26/20

RAPID RESPONSE: COVID-19: Intensive care unit length of stay and ventilation days 

Duan-Porter W | VA Evidence Synthesis Program

Aim: To explore the length of stay in the intensive care unit (ICU) and time on invasive mechanical ventilation for adult patients with COVID-19.

6/20/20

Antithrombotic therapies in COVID-19 Disease: a Systematic Review   

Maldonado E, Tao D, Mackey K | J Gen Intern Med

Aim: To synthesize evidence on thromboembolism incidence and outcomes with antithrombotic therapies in COVID-19.

5/15/20

PREPRINT REVIEW: Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19 

Lindquist I, Mackey K, Edwards S | VA Evidence Synthesis Program

Aim: To provide author feedback and critical appraisal in a similar manner as would be provided by editorial staff of a journal.