COVID-19 Evidence Reviews
as of 10/21/20
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Unpublished Reviews
 
= living review
= draft/preprint   |  
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
latest update
date
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10/21/20
Li Y, Liang M, Gao L, et al. | medRxiv
Aim: To evaluate the effectiveness of using face masks to prevent the spread of SARS-CoV-2. 
RECENTLY UPDATED
10/21/20
Urwin SG, Lendrem BC, Suklan J, et al. | medRxiv
Aim: To evaluate the diagnostic accuracy of a commercial POC test (FebriDx) in patients with suspected COVID-19.
10/21/20
Roshandel MR, Nateqi M, Lak R, et al. | medRxiv
Aim: To review the evidence on the SARS-CoV-2 infectivity of body fluid.
10/20/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/20/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/20/20
Alizadeh S, Ozgoli G | Research Square
10/19/20
Hammoud H, Bendari A, Bendari T, et al. | medRxiv
Aim: To provide a total picture of the SARS-CoV-2 histopathological features of different body organs in postmortem autopsies through a systematic search of the published literature.
10/19/20
Viner RM, Ward J, Hudson L, et al. | medRxiv
Aim: To undertake a systematic review of reviews of the prevalence of symptoms and signs of COVID-19 in those aged under 20 years.
10/16/20
Chen P, Bobrovitz N, Premji Z, et al.  | medRxiv
Aim: To review the evidence on transmissibility of SARS-CoV-2, including mechanistic correlates of overdispersion, viral kinetics, and infectiousness.
RECENTLY UPDATED
10/15/20
Beale S, Hayward A, Shallcross L, et al. | medRxiv
Aim: To review current evidence regarding the asymptomatic proportion of PCR-confirmed SARS-CoV-2 infections based on methodologically-appropriate studies in community settings.
10/15/20
Jenkins D, Paquette M, Sahye-Pudaruth S, et al.  | PROSPERO
10/15/20
Gebremeskel G, Haile T, Gebrewahd G, et al.  | PROSPERO
10/15/20
Atmosudigdo I, Pranata R, Anthonius M, et al.  | PROSPERO
10/15/20
Qi X, Ao G, Wang Y | PROSPERO
10/15/20
Slomka A, Kowalewski M, Zekanowska E, et al.  | PROSPERO
10/15/20
Papapanou M, Papaioannou M, Petta A, et al.  | PROSPERO
10/15/20
Du X, Shi L, Cao W | PROSPERO
10/15/20
Reddy MP, Subramaniam A, Lim ZJ, et al  | medRxiv
Aim: To evaluate the impact of prone positioning on oxygenation and clinical outcomes. 
RECENTLY UPDATED
10/15/20
Carvalho C, Souza AB, Rego CO, et al. | PROSPERO
10/15/20
Elangovan EJ, Kumar VS, Kathiravan A, et al. | medRxiv
Aim: To evaluate the clinical outcomes of repurposed drugs against COVID-19 including Tocilizumab, Remdesivir, Dexamethasome, Lopinavir-ritonavir, Favipiravir, Hydroxychloroquine, and Convalescent plasma therapy. 
10/15/20
Cavalcante T | PROSPERO
10/15/20
Zhou X, Pan J, Wang H, et al.  | PROSPERO
10/15/20
Kumar J, Meena J, Yadav A, et al.  | PROSPERO
10/15/20
Mittal S, Madan K, Mohan A, et al. | PROSPERO
10/15/20
Zhi Y, Gao C, Qin Y | PROSPERO
10/15/20
Francheska BDK, Wilson E, Oni G, et al. | PROSPERO
10/15/20
Epstein A, Mdgela J | PROSPERO
10/15/20
Xu W, Li X, Dozier M, et al. | medRxiv
Aim: To investigate the extent of SARS-CoV-2 transmission in schools. 
RECENTLY UPDATED
10/14/20
Hamam O, Goda A, Eldalal M, et al. | medRxiv
Aim: To build concrete evidence regarding the incidence of cardiac arrhythmia in patients with COVID-19.
10/14/20
Danjuma , Mahgoub Y, Mushtaq K, et al.  | PROSPERO
10/14/20
Huang F, Song J, Zheng B, et al.  | PROSPERO
10/14/20
Boet S, Etherington N | PROSPERO
10/14/20
Mehendale F, Reynolds D, Clayton G, et al.  | PROSPERO
10/14/20
Roberts M, Driggs D, Thorpe M,et al. | arXiv
Aim: To review the evidence on machine learning methodologies for detection and prognostication of COVID-19 from standard-of-care chest radiographs and computed tomography images.
10/14/20
Shi J, Li Y, Zhao L, et al. | Research Square
10/14/20
Douglas M, Dozier M, McSwiggan E, et al.  | PROSPERO
10/14/20
Qi X, Wu B, Zhu Z, et al.  | PROSPERO
10/14/20
Tadesse DB, Wahdey S, Negash M, et al. | Asthma Res Pract
10/13/20
De Kock JH, Latham HA, Leslie SJ, et al. | Research Square
Aim: To identify whether there are any identifiable risk factors for adverse mental health outcomes amongst HSCWs during the COVID-19 crisis. 
10/13/20
Gonzales-Rayas JM, Jerjes-Sanchez C, Martinez-Magallanes DM, et al.  | PROSPERO
10/13/20
Asiimwe IG, Pushpakom S, Turner R, et al | medRxiv
Aim: To continually evaluate the rapidly evolving evidence base on the role of cardiovascular drugs in COVID-19 clinical outcomes (susceptibility to infection, hospitalization, hospitalization length, disease severity, and all-cause mortality).
RECENTLY UPDATED
10/13/20
Rivero-Santana A, Perestelo-Perez L, Ramos-Garcia V, et al.  | PROSPERO
10/13/20
Nguyen A, Elsaid M, Ghula S, et al.  | PROSPERO
10/13/20
Rocha KO, Zanuncio VV, Lima LM | PROSPERO
10/13/20
Pandey R, Gourishankar A | medRxiv
Aim: To evaluate the diagnostic accuracy of FDA authorized serology tests for the detection of SARS-CoV-2 infection.
10/13/20
Huang S, Wang S, Li G, et al. | Medicine
10/13/20
Liu Y, Xie H, Gao H, et al. | Medicine
10/13/20
Tasnim S, Rahman M, Pawar P, et al. | medRxiv
Aim: To assess the current evidence on the epidemiological burden, associated factors, and interventions from the existing literature. 
10/13/20
Wang J, Cui H, Tang H | Research Square
Aim: To understand the clinical manifestations and incidence of gastrointestinal symptoms of Coronavirus disease (COVID-19) in children and discuss the importance of fecal nucleic acid testing.
10/13/20
Yu CC, Hlaing T | PROSPERO
10/13/20
Raya BA, Mijovic H, Donken R, et al.  | Research Square
Aim: To review the outcomes of patients with COVID-19 treated with different pharmacological treatments in randomized controlled trials (RCTs).
10/13/20
Liu Z, Zhang Y | PROSPERO
10/13/20
Hamam O, Goda A, Awad R, et al. | medRxiv
Aim: To build concrete evidence regarding the incidence and mortality of pulmonary embolism (PE) in patients with COVID-19.
10/13/20
Vindrola-Padros C, Singh K, Sidhu MS, et al. | medRxiv
Aim: To analyse the implementation and impact of remote home monitoring models (virtual wards) during COVID-19, identifying their main components, processes of implementation, target patient populations, impact on outcomes, costs and lessons learnt.
RECENTLY UPDATED
10/13/20
Lugli G, Ottaviani MM, Botta A, et al. | medRxiv
Aim: To investigate the management of non-COVID-19 patients across all medical specialties during the pandemic in Italy. 
10/13/20
Pranata R, Lim M, Yonas L, et al.  | PROSPERO
10/13/20
Yao J, Shao G, Cui Y, et al.  | PROSPERO
10/12/20
Schunke L, Andre da Costa C, Antunes RS, et al.  | PROSPERO
10/12/20
de Jesus Dantas Ferreira L, dos Santos Goncalves M, dos Santos Cordeiro G, et al.  | PROSPERO
10/12/20
Barboza J, Chambergo-Michilot D, Velasquez-Sotomayor M, et al.  | PROSPERO
10/12/20
Barboza J, Chambergo-Michilot D, Velasquez-Sotomayor M, et al.  | PROSPERO
10/12/20
Sarma P, Bhattacharyya A, Kaur H, et al.  | PROSPERO
10/12/20
Sarma P, Bhattacharyya A, Kaur H, et al.  | PROSPERO
10/12/20
Sanots G, Silva H, Leite A, et al.  | PROSPERO
10/12/20
Walsh S, Mytton B, Braithwaite V, et al.  | PROSPERO
10/12/20
Sun C, Chen Y, Hu L, et al.  | PROSPERO
10/12/20
Sahu AK, Sahu AK | PROSPERO
10/12/20
Jiaming F, Yingying M, Liang Q | PROSPERO
10/12/20
Hung KC, Sun CK, Chen IW, et al. | PROSPERO
10/12/20
Turner C, Natolanda P | PROSPERO
10/9/20
Levin AT, Meyerowitz-Katz G, Owusu-Boaitey N, et al. | medRxiv
Aim: To assess the age specificity of the infection fatality rate (IFR) for COVID-19 using seroprevalence results from eight national studies (Belgium, England, Hungary, Italy, Netherlands, Portugal, Spain, and Sweden), fifteen seroprevalence studies of specific locations in Europe and the United States, and three countries (Iceland, New Zealand, and Republic of Korea) that have engaged in comprehensive tracking and tracing of COVID-19 infections.
10/9/20
Griswold D, Gempeler A, Kolias A, et al  | medRxiv
Aim: To identify and summarize the available literature regarding the efficacy of different personal protective equipment (PPE) for reducing the risk of COVID-19 infection in health personnel caring for patients undergoing trauma surgery in low-resource environments (LREs).
10/9/20
Kaushal K, Kaur M, Kumar S, et al.  | PROSPERO
10/9/20
Wakhloo T, Chug A, Dixit A, et al . | PROSPERO
10/9/20
Yu Z, Li D, Zhao X, et al.  | PROSPERO
10/8/20
Talarico F, Chakravarty S, Liu Y, et al. | medRxiv
Aim: To review the evidence on the psychiatric side effects associated with chloroquine and hydroxychloroquine.
10/8/20
Guo XG, Cao XJ, Fang KY, et al.  | PROSPERO
10/7/20
Boychuck Z, Ogourtsova T, Znaty A, et al | PROSPERO
10/7/20
Low JM, Amin Z, Peng Mei YNG | PROSPERO
10/7/20
Saadatjoo S, Miri M, Hassanipour S, et al. | medRxiv
Aim: To investigate and synthesize the current evidence on KAPs regarding COVID-19.
UPDATED
10/7/20
Chen Y, Zhu C, Xu Z, et al. | Medicine
10/7/20
Ravindra K, Malik VS, Padhi BK, et al. | medRxiv
Aim: To investigate the role of asymptomatic infection worldwide reported in family-cluster, adults, children, health care workers, and travelers. 
10/7/20
Qiu X, Nergiz AI, Maraolo AE, et al. | medRxiv
Aim: To critically appraise available data about secondary attack rates from people with asymptomatic and pre-symptomatic SARS-CoV-2 infection.
10/7/20
Penna P, Oliveira N, Hermsdorff H | PROSPERO
10/7/20
Anathan VA, Veerakumar AM, Ram Prabhakar V.  | PROSPERO
10/7/20
Costanzo S, Parisi R, Di Castenuovo A, et al  | PROSPERO
10/7/20
Meseret M, Regasa Z, Hailiye G, et al  | PROSPERO
10/7/20
Heath L, Carey M, Lowney A, et al  | PROSPERO
10/7/20
Zhang Y, Yu S, Xu Y, et al. | medRxiv
Aim: To explore the impact of RAS inhibitor use on the risk of SARS-CoV-2 infection and the prognosis of SARS-CoV-2 infected patients, from all published studies. 
10/7/20
Sah SK, Undela K, Chand S, et al.  | medRxiv
Aim: To review the evidence on the safety and efficacy of essential pharmacotherapy during the pharmacological management of COVID-19. 
UPDATED
10/7/20
Diogo P, Lemos e Sousa O, Rodrigues J, et al  | PROSPERO
10/7/20
Wang X, Wang X, Chen JX | PROSPERO
10/6/20
Zhang Z, Ai G, Chen L, et al. | Research Square
Aim: To explore the association of immunological features with COVID-19 severity.
10/6/20
Desai M, Deshpande G, Elenwa F, et al | PROSPERO
10/6/20
Chen J, Gong L, Gong Q, et al | PROSPERO
10/6/20
Silveira LC, da Silva Santos R, da Silva Reis AA | PROSPERO
10/6/20
Ahmad A | Central Council for Research in Ayurvedic Sciences
10/6/20
Ahmad A | Central Council for Research in Ayurvedic Sciences
10/6/20
Xu J | PROSPERO
10/6/20
Saragih ID, Saragih IS, Lin CJ | PROSPERO
10/6/20
Flores GMY, Ramos GT, Cantoral JEH, et al  | PROSPERO
10/6/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/6/20
Hammound A, Khalid T, Thornton H, et al | PROSPERO
10/6/20
Rutkowski S, Czech O, Wrzeciona A, et al  | PROSPERO
10/6/20
Sakuraba A | PROSPERO
10/6/20
Liu J, Yin X, Liao J, et al  | PROSPERO
10/6/20
Rutkowski S, Czech O, Wrzeciono A, et al  | PROSPERO
10/5/20
Taylor E, Macleod K, Scribante J, et al  | PROSPERO
10/5/20
Garcia-Albeniz X, Del Amo J, Polo R, et al. | medRxiv
Aim: To review the evidence on the effectiveness of HCQ to prevent COVID-19.
10/5/20
Kim S, Shin Jae II, Lee KH | PROSPERO
10/5/20
Morales NG, Cotrina SA, Miranda JMA, et al  | PROSPERO
10/5/20
Morales NG, Cotrina SA, Miranda JMA, et al  | PROSPERO
10/5/20
Hernandez MCV, Suarez JAR, Munos CAB, et al  | PROSPERO
10/5/20
Tadesse DB, Gebrewahd GT, Gerensea H | PROSPERO
10/5/20
Mao W, Vos T, Hanson SW, et al  | PROSPERO
10/5/20
Zorrilla E, Ottur M, Luu K, et al  | PROSPERO
10/5/20
Lee J, Chi G | PROSPERO
10/5/20
Guo XG, Li XJ, Cao XJ, et al  | PROSPERO
10/5/20
Cui Y, Yao J, Shao G, et al  | PROSPERO
10/2/20
Neal E, Russell F, Curtis N, et al  | PROSPERO
10/2/20
Siahaan YMT, Puspitasari V, Pangestu AR | Research Square
Aim: To determine the clinical profile, laboratory, and imaging results of encephalitis associated with COVID-19.
10/2/20
Beiter K, Lau FH, Danos D | Research Square
Aim: To evaluate VDD and COVID-19 mortality worldwide during the first 50 days of the pandemic as experienced by each country.
10/2/20
Rahman MM, Bhattacharjee B, Farhana Z, et al. | medRxiv
Aim: To chronicle the prevalence and correlations of symptoms and comorbidities, and associated covariates among the patients.
10/1/20
Doumouchtsis S | PROSPERO
10/1/20
Gebrewahd G, Tadesse D, Gebreamlak G, et al  | PROSPERO
10/1/20
Sethia R, Prasad M, Jagannath S | medRxiv
Aim: To review the evidence on the use of famotidine in COVID-19.
10/1/20
Ahammed T, Anjum A, Rahman MM, et al. | medRxiv
Aim: To estimate the R0 and CFR of COVID-19 and assess whether the parameters vary in different regions of the world.
UPDATED
10/1/20
Morales Gomez CBM, Sagredo K, Saavedra JA | PROSPERO
10/1/20
Ladapo JA, McKinnon JE, McCullough PA, et al. | medRxiv
Aim: To determine if hydroxychloroquine (HCQ) reduces the incidence of new illness, hospitalization or death among outpatients at risk for or infected with SARS-CoV-2 (COVID-19).
10/1/20
Luna E, Figueiredo G, Campos S | PROSPERO
10/1/20
Dowsett L, Mastikhina L, Egunsola O, et al  | PROSPERO
9/30/20
Galindo L, de Olivera Neto OB, Pinheiro IL, et al  | PROSPERO
9/30/20
Gundeti MS, Ahmad A, Rai AK, et al  | PROSPERO
9/30/20
Poole-Wright K, Gaughran F, Chalder T | PROSPERO
9/30/20
Shao G, Yang D, Huang S | PROSPERO
9/30/20
Liampas A, Zis P | PROSPERO
9/30/20
Goncalves AK, Medeiros K, Sarmento AC, et al  | PROSPERO
9/30/20
Riches S, Azevedo L, Valmaggia L | PROSPERO
9/29/20
Hassanipour S, Faradonbeh SB, Momeni K, et al. | medRxiv
Aim: To investigate the clinical manifestation include signs and symptoms, laboratory results, and perinatal outcomes in pregnant women with COVID-19.
9/29/20
Wang Z, Zhang J, Ma Y | PROSPERO
9/29/20
Fan H, Wang L | PROSPERO
9/29/20
Munro A, Gray M, Mohan A, et al | PROSPERO
9/29/20
Sarkar S, Khanna P, Sing A | PROSPERO
9/29/20
de Souza TA, de Almeida Medeiros A, da Silva Nunes AD, et al  | PROSPERO
9/29/20
Thompson W, Teoh L | PROSPERO
9/29/20
Rahimi M, Ghaffari S, Daneshvar S | PROSPERO
9/29/20
Verdugo-Paiva F, Acuna MP, Sola I, et al. | medRxiv
Aim: To provide a timely, rigorous and continuously updated summary of the evidence available on the role of remdesivir in the treatment of patients with COVID-19.
9/29/20
Tian L, Shao X | PROSPERO
9/29/20
JunJian M,, KeFan W, PeiXin J | PROSPERO
9/29/20
Yan Y, Mao J, Gao X, et al  | PROSPERO
9/29/20
Wang YY, Xiang Yu-Tao, Jin Yu, et al  | PROSPERO
9/28/20
Rubio-Rivas M, Mora-Lujan JM, Montero A, et al. | medRxiv
Aim: To summarize evidence about the effect of TCZ to treat severe COVID-19.
9/28/20
Wungu C, Khaerunnisa S, Putri E, et al. | PROSPERO
9/28/20
Hashan MR, Smoll N, King C, et al. | PROSPERO
9/28/20
Lazarus G, Audrey J, Wangsaputra V, et al  | medRxiv
Aim: To investigate the prognostic value of admission blood glucose (BG) in predicting COVID-19 outcomes, including poor composite outcomes (mortality/severity), mortality, and severity. 
UPDATED
9/28/20
Saragih ID, Suarilah I | PROSPERO
9/28/20
Leons-Rojas J, Restrepo-Rodas G, Mancero R, et al. | PROSPERO
9/28/20
Griswold D, Gempeler A, Kolias A, et al  | medRxiv
Aim: To summarise the effects of different personal protective equipment (PPE) for reducing the risk of COVID-19 infection in health personnel caring for patients undergoing trauma surgery.
UPDATED
9/28/20
Adjei G, Thomford N, Enuameh Y | PROSPERO
9/28/20
Kharoud HK, Asim R, Siegel L, et al. | medRxiv
Aim: To conduct a systematic review and meta-analysis to assess the prevalence of various clinical symptoms and laboratory findings of COVID-19 in children.
UPDATED
CLINICAL CHARACTERISTICS
9/28/20
Espinoza SKF, Vasquez MT, Miranda JMA | PROSPERO
9/28/20
Del Riccio M, Lorini C, Bonaccorsi G, et al. | medRxiv
Aim: To review the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g. severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients.
9/28/20
Hung D, Aziz JA, Ghula S, et al.  | PROSPERO
9/28/20
Concha GMP, Gutierrez JBO, Flores AAR | PROSPERO
9/28/20
Neil-Sztramko S, Dobbins M | PROSPERO
9/25/20
Dowsett L, Egunsola O, Mastikhina L, et al. | PROSPERO
9/25/20
Dowsett L, Clement F, Farkas B, et al. | PROSPERO
9/25/20
Fang C, Zhou Z, Zhou M, et al. | Research Square
Aim: To examine the relationship between BMI and severity and mortality of patients with coronavirus disease 2019 (COVID-19).
9/25/20
Moulin M, Ali S, John-Baptiste A | PROSPERO
9/25/20
Maheu-Cardotte MA, Lapierre A, Fontaine G, et al. | PROSPERO
9/25/20
Maitra S, Behera S, Gouri M, et al.  | PROSPERO
9/25/20
Naveed S, Akhtar P, Meraj H, et al. | PROSPERO
9/25/20
Yadav A, Ghosh S, Dubey S | PROSPERO
9/25/20
Currie C, Larouche R, Voss L , et al | Syst Rev
UPDATED
9/25/20
Brotis A, Karvouniaris M, Poulakou G | PROSPERO
9/25/20
Pranata R, July J | PROSPERO
9/25/20
Michelen M, Sigfrid L, Manoharan L, et al.  | PROSPERO
9/24/20
Variava T, Watermeyer | PROSPERO
9/24/20
Ali R, Farah E, El-Zein M, et al  | PROSPERO
9/24/20
Wang Y, Li W, Jiang Z, et al. | Medicine
9/24/20
Malik A, McFadden S, Pischel L, et al  | PROSPERO
9/24/20
Wolf S, Zeibig J, Seiffer B, et al. | Research Square
Aim: To provide a systematic overview of the literature with regard to associations between physical activity (PA) and depression and anxiety during the COVID-19 pandemic. 
9/24/20
Pegorari MS, Matos AP, Iosimuta NCR, et al. | Rev Assoc Med Bras
9/24/20
Zhang Y, Ren T, Li H, et al  | Medicine
9/24/20
Gebremeskel G, Haile T | PROSPERO
9/24/20
Qian W, Ye Y, Zuo L, et al. | Research Square
Aim: To assess the safety of ICI application in COVID-19 patients and to make reasonable recommendations by reviewing available publications.
9/24/20
Zawai AT, Alwafi H, Naser AY, et al  | PROSPERO
9/24/20
Guadie H, Zeleke A, Desta C, et al  | PROSPERO
9/24/20
Peter HJ, Vancsa S, Kiss S, et al  | PROSPERO
9/24/20
Xiong X, Chi J, Gao Q | Research Square
Aim: To determine the prevalence and risk factors of thrombotic events on COVID-19 patients.
9/24/20
Du L, Chen Y, Li Y, et al. | Medicine
9/24/20
Liu M, Zhu H, He Y, et al. | Medicine
9/24/20
Mellor M, Bast A, Jones N, et al. | medRxiv
Aim: To assess whether people living with HIV (PLWH) are at increased risk of COVID-19 mortality or adverse outcomes, and whether antiretroviral therapy (ART) influences this risk. 
9/24/20
Dar JA, Amber S, Mujaddadi A | PROSPERO
9/24/20
Peng J, Wu Z, Zhong H, et al. | Medicine
9/24/20
Zhangmeng X, Yong C, Yu D, et al  | Medicine
9/24/20
Zhang J, Li S, Zhao C, et al. | Medicine
9/23/20
Davids J, Monrouxe L, Hockey P, et al  | PROSPERO
9/23/20
Tierney S, Wong G, Turk A, et al | PROSPERO
9/23/20
Gagliardi R, Pires G | PROSPERO
9/23/20
Wang X, Ma S  | PROSPERO
9/23/20
Tolsa MD, Malas O | PROSPERO
9/23/20
Vasquez MT, Espinoza SKF, Miranda JMA, et al  | PROSPERO
9/21/20
Ngo BT, Marik P, Kory P, et al. | medRxiv
Aim: To determine the potential time course for development of treatments and vaccines, focusing on availability now and continuing in the last half of 2020. 
9/21/20
Wang B, Andraweera P, Elliot S, et al.  | PROSPERO
9/21/20
Civi RM, Azhir A, Landi A | PROSPERO
9/21/20
Rubio L, de las Heras SM | PROSPERO
9/21/20
Zhang X, Liao X | PROSPERO
9/21/20
Bazargani MHM, Rastad H, Shafiabadi N | PROSPERO
9/21/20
Mohanty R, Meher BR, Padhy BM, et al.  | PROSPERO
9/21/20
Xie B, Yang Z, Liu C, et al.  | PROSPERO
9/21/20
Lee KW, Yap SF, Ngeow YF, et al.  | PROSPERO
9/21/20
Butt M, Shirke S, Makkar S, et al.  | PROSPERO
9/21/20
Butt M, Shirke S, Makkar S, et al.  | PROSPERO
9/21/20
Shekar R, Sheikh AB, Sagheer S, et al.  | PROSPERO
9/21/20
Sarah ID, Ice SS, Batubara SO, et al.  | PROSPERO
9/21/20
Baral R, Vssiliou V | PROSPERO
9/21/20
Wang Q, Wang T, Wang Y, et al.  | PROSPERO
9/21/20
Yan H, Ding Y, Guo W | PROSPERO
9/21/20
Ramonfaur D, Gonzalez CA, Paredes-Vazquez JG | medRxiv
Aim: To summarize all the proposed mechanisms by which PTX may aid in the treatment of COVID-19, as well as prevent its deadly complications. 
9/21/20
Ferreira-Souza LF, Torres-Nunes L, Moura-Fernandes MC, et al.  | PROSPERO
9/21/20
Steare T, Wood L, Goulding L, et al.  | PROSPERO
9/21/20
Ojimbo KO, Kisangala E, Namisango E, et al.  | PROSPERO
9/21/20
Sadjadi M, Moerschel KS, Petticrew M | medRxiv
Aim: To systematically review qualitative literature on social distancing in order to identify and describe factors that enable or prevent its implementation. 
9/21/20
Maria van Bohemen AEC, Skarp J, Hauck K | PROSPERO
9/21/20
Wang Y, Chen X, Luo G, et al. | PROSPERO
9/21/20
Wang Y, Chen X, Luo G, et al.  | PROSPERO
9/21/20
Zhan ZQ, Guo XG, Cai GN | PROSPERO
9/21/20
Kim E, Jeong A | PROSPERO
9/21/20
Du M, Zhao J, Yin X, et al. | medRxiv
Aim: To analyze the risk factors (vital signs) that affect the prognosis of COVID-19 patients.
9/21/20
Wildwing T, Holt N, et al. | medRxiv
Aim: To provide health professionals with better accessibility to available evidence, this paper summarises findings from a systematic overview of systematic reviews of the neurological symptoms seen in patients with COVID-19.
UPDATED
9/21/20
Lu H, Chen C, Wu Y | PROSPERO
9/21/20
Kadharusman MM, Sutanto RL, Tjoa K, et al.  | PROSPERO
9/21/20
Levi J, Hill A, Heath K, et al.  | PROSPERO
9/21/20
Wu X, Li W, Qi Z, et al. | PROSPERO
9/21/20
Edwards T, Santos VS, Wilson AL, et al. | medRxiv
Aim: To describe whether SARS-CoV-2 viral loads (VLs) and cycle thresholds (CTs) vary by sample type, disease severity and symptoms duration. 
UPDATED
9/18/20
Abeldano RA, Coca SM, Abeldano GF, et al. | Research Square
Aim: To assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection.
9/18/20
De Guzman K, Snoswell CL, Smith AC | PROSPERO
9/18/20
Benzouak T, Rao S, Kisely S, et al.  | PROSPERO
9/18/20
Dobbins M | National Collaborating Centre for Methods and Tools
9/18/20
Walle IV, Leitmeyer K, Broberg EK | medRxiv
Aim: To review the clinical performance of SARS-CoV-2 nucleic acid, viral antigen and antibody tests
9/18/20
Axfors C, Schmitt AM, Janiaud P et al. | medRxiv
Aim: To estimate the effects of hydroxychloroquine and chloroquine on 4 survival in COVID-19 from all currently available RCT evidence, published and unpublished
9/18/20
Corona G, Pivonello R, Isidori A, et al.  | PROSPERO
9/18/20
Chess K, Jacobson TA, Smith LE, et al. | Research Square
Aim: To synthesize literature on SARS-CoV-2 seroprevalence studies, including sampling frames, study characteristics, assay test performance characteristics, and proportion of participants with IgG and IgM SARS-CoV-2 antibodies.
9/17/20
Lo K, Liu S | PROSPERO
9/17/20
Ang Y, Soo R, Soon YY | PROSPERO
9/17/20
Agarwal A, Basmaji J, Faisal H, et al.  | PROSPERO
9/17/20
Alcock H, Moppett E, Moppett I | PROSPERO
9/17/20
Abdallah I, Aabdien M | PROSPERO
9/17/20
Meena J, Jain S, Kumar j, et al.  | PROSPERO
9/17/20
van Zuylen M, Bribnau A, Admiraal M, et al.  | PROSPERO
9/17/20
Chen Y, Zuo YY, Zheng H, et al.  | PROSPERO
9/15/20
Elsayed HH, Hassaballa AS, Ahmed TA, et al. | Research Square
Aim: To review the evidence on the use of ECMO for COVID-associated ARDS to study its outcomes.
UPDATED
9/15/20
Beaudry G, Zhong S, Whiting D, et al. | SSRN
Aim: To synthesise the evidence on outbreaks of highly contagious diseases in prison.
UPDATED
9/15/20
Simadibrata DM, Calvin J, Wijaya AD, et al. | medRxiv
Aim: To investigate whether NLR levels on admission could predict the severity and mortality of COVID-19 patients.
9/15/20
Botelho MS, Bolfi F, Leite RGOF, et al. | Research Square
Aim: To evaluate the safety of CQ and HCQ from malarial and non-malarial randomized clinical trials (RCTs).
UPDATED
9/14/20
Zuniga RAA, Coca S, Abeldano G, et al. | medRxiv
Aim: To assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection. 
9/14/20
Abbas KS, Luu M, Elghezewi ASK, et al. | Research Square
Aim: To review the current decontamination methods to reuse masks and respirators.
9/14/20
Ji HJ, Su Z, Zhao R, et al. | medRxiv
Aim: To investigate whether abnormal fibrinolysis is a culprit or protector or both in the clinical progression of COVID-19.
9/14/20
Kaur U, Chakrabarti SS, Patel TK | medRxiv
Aim: To provide a pooled estimate of the effect of RAAS blocker usage on COVID-19 outcomes. 
9/14/20
Chen X, Chen Z, Azman AS, et al. | medRxiv
Aim: To evaluate the quality of serological studies and provide a global picture of seroprevalence across demographic and occupational groups, and to provide guidance for conducting better serosurveys.
9/14/20
Cirillo N | medRxiv
Aim: To facilitate a timely understanding of the differences in the prevalence of gustatory disturbances (GD) in individuals infected with SARS-CoV-2.
9/11/20
Maguire BJ, Guerin PJ | Wellcome Open Res
9/11/20
De Lorenzo A, Kasal D, Tura B, et al. | medRxiv
Aim: To review the evidence on cardiac complications of COVID-19.
9/11/20
Yan H, Ouyang Y, Wang L, et al. | Medicine
9/11/20
Liu Y, Fu X, Xie C | Medicine
9/11/20
Gnanvi JE, Salako VK, Kotanmi B, et al. | medRxiv
Aim: To conduct a global systematic literature review to summarize trends in the modelling techniques used for Covid-19
9/11/20
Gao W, li J, Huang G | Medicine
9/11/20
Torres AZ, Lopez-Leon S, Muthuvel T, et al. | medRxiv
Aim: To systematically review the safety and efficacy outcomes of using antivirals for the treatment of COVID-19.
UPDATED
9/10/20
Carreno Hernandez FL, Cardena Bolivar YR | PROSPERO
9/10/20
Bahji A, Crickford D | PROSPERO
9/10/20
Li Y, Weng Q, Huang X, et al. | Medicine
9/10/20
Singh A, Keri V | PROSPERO
9/10/20
Christensen H, Turner K, Trickey A, et al. | medRxiv
Aim: To provide a rapid review and appraisal of the literature on mathematical models investigating COVID?19 infection in a university setting.
9/10/20
Kula B, Schwartz I | PROSPERO
9/10/20
Meena J, Singh M, Jaiswal N, et al.  | PROSPERO
9/10/20
Shekhar R, Sheikh AB, Upadhyay S, et al.  | PROSPERO
9/10/20
Staibano P, Sommer D, McHugh T | PROSPERO
9/10/20
Divatia J, Nadkarni A, Vijayakumaran SC | PROSPERO
9/10/20
Jones M, Cashin A, Arnold R, et al.  | PROSPERO
9/10/20
Wang Y, Ma , Li Y, et al.  | PROSPERO
9/10/20
Zhang Y, Xie H, Li Y, et al. | Medicine
9/10/20
Yu Z, Wang P, Chen B, et al.  | PROSPERO
9/10/20
Bendezu Quispe GJP, Hernandez Vasquez AA, Comande D | PROSPERO
9/10/20
da Silva Junior SV, de Godoi Caceres NT, Lordao AV, et al.  | PROSPERO
9/10/20
Shekar R, Sheukh AB, Upadhyay S, et al.  | PROSPERO
9/10/20
Ma J, Tang L, Feng Y | PROSPERO
9/10/20
Wilson L, Michtalik H, Robinson K | PROSPERO
9/10/20
Hailay A, Aberhe W, Zereabruk K, et al  | Asthma Res Pract
9/10/20
Elshafei M, Khalil A, El-Bardissy A, et al. | Medicine
9/10/20
Huang T, Song D, Wei Y, et al.  | PROSPERO
9/10/20
Liu Y, Yang Y, Chen Y, et al. | Medicine
9/9/20
Cairoli FR, Mazzoni A, Berrueta M, et al.  | PROSPERO
9/9/20
Chen C, Lu H, Wi Y | PROSPERO
9/9/20
Amani B, Khanijahani A, Amani B | PROSPERO
9/9/20
Hoang T | medRxiv
Aim: To examine the characteristics of repositive COVID-19 cases.
9/9/20
Mu R, Yi Z, Xu C, et al.  | PROSPERO
9/9/20
Wu Y, Li H, Li S  | Research Square
Aim: To summarize current evidence regarding the risk of death and the severity of COVID-19 as well as risk factors for severe COVID-19.
9/9/20
AbdelMassih A, Fouda R, Essam R, et al. | Research Square
Aim: To use the relevant case reports and series to determine the percentage of newborns who test positive in COVID-19 positive mothers.
9/9/20
Sze S, Pan D, Gray LJ, et al. | medRxiv
Aim: To determine whether the risk of SARS-CoV-2 infection, COVID-19 intensive care unit (ICU) admission and mortality are associated with ethnicity. 
9/9/20
Angulo-Bazan Y, Solis G, Acosta J, et al. | medRxiv
Aim: To describe the characteristics of SARS-CoV-2 infection among household members with a confirmed primary case of COVID-19 in low burden districts in Metropolitan Lima. 
9/9/20
Peng A, Wang X | PROSPERO
9/9/20
Joo JY, Liu M | PROSPERO
9/9/20
Iloanusi S, Mgbere O, Essein E | PROSPERO
9/9/20
Li X, Liu C, Mao Z, et al. | Research Square
Aim: To evaluate the predictive values of NLR on disease severity and mortality in COVID-19 patients.
9/9/20
Goettens M, Cademartori M, Azevedo M, et al.  | PROSPERO
9/9/20
Jayaraj R | PROSPERO
9/9/20
Marziale MHP, Cassenote AJF, Fracarolli IFL, et al. | PROSPERO
9/9/20
Anikpezie N, Ngujede A, Osaghae I, et al.  | PROSPERO
9/9/20
Amani B, Amani B, Khanijahani A | PROSPERO
9/9/20
Puppo H, Torres-Castro R, Vasconcello-Castillo L, et al. | PROSPERO
9/8/20
Pamplona EA, de Oliveira RAF, da Silva Ferreira BNM | PROSPERO
9/8/20
Meena JP, Gupta AK, Pandey RM | PROSPERO
9/8/20
Beressa TB, Sahilu T, Deyno S | medRxiv
Aim: To systematically review and summarize the influence of Renin-Angiotensin-Aldosterone System (RAAS) inhibitors on the outcome of COVID_19 patients with hypertension.
9/8/20
Serrano-Ripoll M, Ricci-Cabello I, Zamanillo-Campos R, et al. | PROSPERO
9/8/20
Getnet B, Degu A, Yenealem F, et al.  | PROSPERO
9/8/20
Sarfraz A, Sarfraz Z, Sanchez-Gonalez MA, et al. | medRxiv
Aim: To investigate whether remdesivir is effective for treating COVID-19 including reduced in-hospital adverse events, oxygen support, and mortality rates.
9/8/20
Cui L, Cheng W, Li Y, et al.  | PROSPERO
9/8/20
Liu Q, Mabilisa S, Mujuru K | PROSPERO
9/8/20
Giuffre M, Palmucci S | PROSPERO
9/8/20
Dou X, Zhang Y, Ma P, et al.  | PROSPERO
9/8/20
Zhu X, Luo Z, Cheng X, et al.  | PROSPERO
9/8/20
Zhu X, Chi W, Luo Z, et al.  | PROSPERO
9/8/20
Kurt M, Abasiyanik Z, Kahraman T | PROSPERO
9/8/20
Segawa I, Ouma KO, Nate RW, et al.  | PROSPERO
9/7/20
Palsuledesai S, Wagle S, Thakur H, et al  | PROSPERO
9/7/20
Widding-Havneraas T, Chaulagain A, Lyhmann I, et al  | PROSPERO
9/7/20
Majid A | PROSPERO
9/7/20
Monroy CG, Martinez EM, Sanchez CMO, et al  | PROSPERO
9/7/20
Tristao LS, Bernardo WM | PROSPERO
9/7/20
Khan S, Mishra P, Parveen R, et al  | PROSPERO
9/7/20
Campbell F, Blank L, Cantrell A, et al  | PROSPERO
9/7/20
Brainard J, Pond K, Hooper L, et al  | PROSPERO
9/4/20
Wang J, Mo Y, Su Y, et al. | medRxiv
Aim: To systematically analyze the chest CT imaging features of children with COVID-19 and provide references for clinical practice. 
9/4/20
Paul D, Gupta A, Maurya AK | medRxiv
Aim: To evaluate research done, prior to COVID-19 pandemic, on various decontamination methods for reprocessing of N95-FFRs.
9/4/20
Sarkar S, Khanna P, Singh A | PROSPERO
9/3/20
Liu N, Zhang T, Ma L, et al. | Medicine
9/3/20
Zhou M, Liang Q, Pei Q, et al. | Medicine
CANDIDATE THERAPEUTICS
9/3/20
Wen D, Shi Y, Zhang X, et al. | Medicine
9/3/20
Xingxianf R, Xiankun W | PROSPERO
9/3/20
Zheng P, Bao L, Yang W, et al. | Medicine
CLINICAL CHARACTERISTICS
9/3/20
Chen C, Weng Q, Li Y, et al. | Medicine
9/3/20
Rattka M, Imhof A, Baymhardt M, et al  | PROSPERO
9/3/20
Ananthan Vam Bhat A, Reddy MM, et al  | PROSPERO
9/3/20
Yang Y, Liu X, Liu Y, et al. | Medicine
CANDIDATE THERAPEUTICS
9/3/20
Ching LY, Qiao F, Weihan L, et al  | PROSPERO
9/3/20
Liu N, Zhang T, Ma L, et al. | Medicine
9/3/20
Tian H, Xue Y, Yao RR, et al | Medicine
9/3/20
Regmi K, Lwin C | PROSPERO
9/3/20
Zhou K, Dong S, Wang K, et al. | Medicine
9/3/20
Indraccolo U | PROSPERO
9/3/20
Luo W, Nie Y, Tan Y, et al  | PROSPERO
9/3/20
Golinelli D, Boetto E, Maietti E, et al. | medRxiv
Aim: To investigate the association between SARS-CoV-2 infection and ABO blood group polymorphism, and determine SARS-CoV-2 positive individuals odds of having a specific blood group compared to controls.
9/3/20
Rooney A, Badenoch J, Watson C, et al  | PROSPERO
9/3/20
Mohanty R, Meher BR, Biswamohan P, et al  | PROSPERO
9/3/20
Huang J, Wu L, Ren X, et al. | Medicine
9/2/20
Innes N, Johnson I, Al-Yaseen W, et al. | medRxiv
Aim: To identify which clinical dental procedures do generate droplets and aerosols with subsequent contamination, and for these, characterise their pattern, spread and settle.
9/2/20
Parohan M, Yaghoubi S, Djalali M, et al. | medRxiv
Aim: To summarize available studies on the association between acute kidney injury and severity of COVID-19 infection. 
9/2/20
Mariadas R, Jayakody S | PROSPERO
9/2/20
Karam M, Althuwaikh S, Alazemi M, et al. | medRxiv
Aim: To compare the performance of chest computed tomography (CT) scan versus reverse transcription polymerase chain reaction (RT-PCR) in the initial diagnostic assessment of coronavirus disease 2019 (COVID-19) patients. 
9/2/20
Lau V, Rewa O, Sebastianski M, et al  | PROSPERO
9/2/20
Jacques TL, Nyasulu P, Birhanu A | PROSPERO
9/2/20
Maitra S, Baidya DK, Bhattacharjee S, et al. | medRxiv
Aim: To know worldwide prevalence of thromboembolic events in COVID-19 patients.
9/2/20
Su Z, Wagers S, Lopez E, et al. | Research Square
9/2/20
Rostami A, Sepidarkish M, Leeflang M, et al. | medRxiv
Aim: To estimate the global and regional anti-SARS-CoV-2 seroprevalence rates in humans and assess whether seroprevalence associates with geographical, climatic and socio-demographic factors. 
9/2/20
Tomfohr-Madsen L, Racine N, Lebel C, et al  | PROSPERO
9/2/20
Sarkar S, Khanna P, Singh A | PROSPERO
9/2/20
Wingert A, Pillay J, Gates M, et al. | medRxiv
Aim: To determine the magnitude of association between potential risk factors and risk of severe outcomes of COVID-19.
UPDATED
9/2/20
Hseih E, Conway R, Konig M, et al  | PROSPERO
9/2/20
Parkinson N, Rodgers N, Fourman MH, et al. | medRxiv
Aim: To identify host factors involved in human betacoronavirus infection (SARS-CoV-2, SARS-CoV, MERS-CoV, seasonal coronaviruses).
9/2/20
Kenmoe S, Kengene-Nde C, Ebogo-Belobo JT, et al. | medRxiv
Aim: To clarify the prevalence of respiratory viruses in children with bronchiolitis in the coronavirus disease 2019 pandemic context. 
9/2/20
Su Z, McDonnell D, Liang B, et al. | Research Square
9/2/20
Kataoka Y, Oide S, Ariie T, et al. | medRxiv
Aim: To investigate the methodological quality of COVID-19 systematic reviews (SRs) indexed in medRxiv and PubMed, compared with Cochrane COVID Reviews.
9/1/20
Galbadage T, Jalali AM, Khoury SG, et al  | PROSPERO
9/1/20
Borstein S | Newfoundland and Laborador Centre for Applied Health Research
9/1/20
Maghrabi K, Alsamman A, Patel S | PROSPERO
9/1/20
Nieuwlaat R | PROSPERO
9/1/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
9/1/20
Tripura K, Karmakar N, Datta A, et al  | PROSPERO
9/1/20
Kovoor J, Tivey D, Ovenden C, et al  | PROSPERO
9/1/20
Coclite D, Napoletano A, Gianola S, et al | medRxiv
Aim: To review the evidence on the effectiveness of wearing face masks in the community to prevent SARS-CoV-2 transmission.
9/1/20
Saleh AS, Roshdy A, Elsayed AS, et al  | PROSPERO
9/1/20
Thomas PE, Javeth A | PROSPERO
9/1/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
9/1/20
Zhou X, Cheng Z, Hu Y | PROSPERO
9/1/20
Hughes S, Canfell K, Carle C, et al  | PROSPERO
9/1/20
Habteyes T, Gamtesa D, Gutema G | PROSPERO
9/1/20
Santos MO, Avelino M, Carneiro LC, et al  | PROSPERO
9/1/20
Saliva PCR for the diagnosis of SARS-CoV-2: a systematic review and meta-analysis | PROSPERO
9/1/20
Tadesse B, Getahun H, Alemu Y | PROSPERO
9/1/20
Vuncannon J, Adler J, Bennett S, et al  | PROSPERO
9/1/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
8/31/20
Post N, Eddy D, Huntley C, et al. | medRxiv
Aim: To comprehensively evaluate the evidence describing the antibody response to SARS-CoV-2.
8/31/20
Shrotri M, van Schalkwyk MCI, Post N, et al. | medRxiv
Aim: To summarize current understanding of the cellular response to SARSCoV-2 infection, specifically exploring the role that T cell-mediated immunity might play in resistance to severe infection, clinical and virological recovery, and long-term protection.
8/31/20
Lopes-Junior L, Bomfim E, da Silveira DSC, et al. | BMJ Open
8/31/20
Baxter S, Barnes A, Lee C, et al. | Research Square
Aim: To examine evidence on initiatives to increase peoples’ involvement in local decision-making, with a focus on how this may be affected by resource constraints.
8/31/20
Mohamed MFH, A-Shokri S, Yousaf Z, et al. | medRxiv
Aim: To systematically review the literature and explore the pooled prevalence of VTE, PE, and DVT in critically ill COVID-19 patients.
8/31/20
Jackson L, Danila M, Owensby J, et al  | PROSPERO
8/31/20
Liu M, Zhu H, Xiong Q, et al  | Medicine
8/31/20
Chung M, Beauchesne AR, Cahoon DS, et al | PROSPERO
8/29/20
Tesfa D, Abebaw S, Digssie A, et al  | PROSPERO
8/28/20
Seidu S, Kunutsor SK, Khunti K, et al  | PROSPERO
8/28/20
Agarwak L, Agarwal A | PROSPERO
8/28/20
Kim MS, An MH | PROSPERO
8/28/20
Karimzadeh S, Elsaid M, Khanh NSL, et al  | PROSPERO
8/28/20
O'Leary T, Iqbal J | PROSPERO
8/28/20
Schulze A, Brand F, Berger N, et al  | PROSPERO
8/28/20
Baker M, Lee L, Hill T, et al  | PROSPERO
8/28/20
Ji B, Xu J | PROSPERO
8/28/20
Ahmad A, Rai AK, Negandhi H, et al  | PROSPERO
8/28/20
Wang J, Zhu X, Sun Y, et al. | Medicine
8/28/20
Tan BBJ, Devi MK | PROSPERO
8/28/20
Torres MAR, Balbin PV, Torres MMR, et al  | PROSPERO
8/28/20
Sarkar S, Khanna P, Singh A | PROSPERO
8/28/20
Vergara-Buenaventura A, Castro-Ruiz C, Chea EC | PROSPERO
8/28/20
Ramirez CR, Silvila CO, Verdugo F | PROSPERO
8/28/20
de Almeida I, Cunha L, Martimbianco AL, et al  | PROSPERO
8/28/20
Chan M, Han Y | PROSPERO
8/28/20
Huang X, Yuan K, Zhang Y, et al  | PROSPERO
8/28/20
Allan S, Clarke T | PROSPERO
8/28/20
Nguyen L, Ryan K | PROSPERO
8/27/20
Boonyawat K, Chantrathammachart P, Namthaveg P, et al. | Research Square
Aim: to explore the incidence of venous and arterial thromboembolism among COVID-19 patients requiring hospitalization.
8/27/20
Walz L, Cohen AJ, Rebaza AP, et al. | Research Square
Aim: To evaluate role of Janus-kinase inhibitors and Type I interferons in COVID-19 patients.
8/26/20
Mendonca K, Jacome A, Silva B, Patino C, et al | PROSPERO
8/26/20
Sterne J, Diaz J, Villar J, et al  | Trials
8/26/20
Bayona HH, Cabaluna IT, Dans L, et al  | PROSPERO
8/26/20
Singh S, Khera D, Chugh A, et al | Research Square
Aim: To evaluate the efficacy and safety of Tocilizumab in comparison to standard therapy in the treatment of COVID-19 in adult patients.
8/26/20
Xie Y, Wang Z, Liao H, et al. | Research Square
Aim: To summarize the epidemiologic traits, clinical spectrum, CT results and laboratory findings of the COVID-19 pandemic.
UPDATED
8/26/20
O'Sullivan L, Killeen RP, Doran P, et al. | HRB Open Research
8/26/20
Batra K, Batra R, Sharma M, et al  | PROSPERO
8/26/20
McGarrigle L, Boulton E, Todd C | Research Square
Aim: To identify and evaluate existing apps and websites to support independent engagement in strength and balance exercises by older people.
8/26/20
Zhou Q, Ye S | PROSPERO
8/26/20
Kizhakekara RN, Uahwatanasakul W, Russell F, et al | PROSPERO
8/26/20
O'Leary T | PROSPERO
8/26/20
Kumar N, Janmohamed K, Nyhan K, et al. | Research Square
8/26/20
Azhir A, Azhir A, Clvi MM, et al  | PROSPERO
8/26/20
Syeda HB, Syed M, Sexton KW, et al. | medRxiv
Aim: To conduct a systematic literature review on the role of ML as a comprehensive and decisive technology to fight the COVID-19 crisis in the arena of epidemiology, diagnosis, and disease progression.
8/26/20
Zheng J, Yan Z, Bi Q, et al  | PROSPERO
8/25/20
Bhamani S, Tabani A, Ahmed S, et al | PROSPERO
8/25/20
Kong X, Qi Y, Huang J, et al  | medRxiv
Aim: To review the evidence on the prevalence of cancer in coronavirus disease 2019 (COVID-19)-infected patients and the severe illness incidence and mortality of COVID-19 patients with cancer.
8/25/20
Abdelrahman Z, Liu Q, Jiang S, et al. | medRxiv
Aim: To estimate the impact of current treatments on the efficacy and safety of COVID-19 by a meta-analysis.
8/25/20
Karsenti N, Elsayed S | PROSPERO
8/25/20
Simadibrata DM, Pandhita BAW, Ananta ME, et al. | medRxiv
Aim: To evaluate the association between PLR levels on admission and the severity of COVID-19 patients. 
8/25/20
Elsawah H, Elsokary M, Elshafie A, et al  | PROSPERO
8/25/20
Gastine S, Pang J, Boshier FAT, et al. | medRxiv
Aim: To describe viral dynamics and estimate the effects of antivirals used to-date.
8/25/20
Booth G, Williams D, Patel H, et al  | PROSPERO
8/24/20
Liang M, Tan S | PROSPERO
8/24/20
Huang R, Xie L, He J, et al  | PROSPERO
8/24/20
Siegel A, Zuo Y, Moghaddamcharkari | PROSPERO
8/24/20
Liu D, Tian Q, Cao M, et al  | PROSPERO
8/24/20
Orimadegun A, Orimadegun B, Adepoju A | PROSPERO
8/22/20
Vieira LG, Camargo LJS, Schneider G, et al. | medRxiv
Aim: To synthesize the scientific evidence on the repercussions of the COVID-19 pandemic on the mental health of pregnant and puerperal women.
8/22/20
Jefferson T, Spencer EA, Brassey J, et al. | medRxiv
Aim: To review the evidence comparing SARS-CoV-2 culture with reverse transcriptase polymerase chain reaction (rt-PCR).
8/21/20
Farooqi A, Gillies C, Khunti K | PROSPERO
8/21/20
Lagos da Silva R, de Morais Gouveia GP, Cunha SV | PROSPERO
8/21/20
Arantes do Amaral MS, Mendes KDS, Hyppolitp MA | PROSPERO
8/21/20
Karabay M, Cinar N, Suzan OK, et al  | PROSPERO
8/21/20
Su Z, Wagers S | PROSPERO
8/21/20
Makram OM, Elfert M, Kouz B, et al  | PROSPERO
8/21/20
Milanese S, Swaminathan N, Shah P, et al  | PROSPERO
8/21/20
Lago da Silva R, dos Santos Souza AT, da Silva Lopes T | PROSPERO
8/21/20
Jiang F, Li R | PROSPERO
8/20/20
Bhamani S, Sajid I, Makhdoom A, et al  | PROSPERO
8/20/20
Su Z, Bently B, Shi F | PROSPERO
8/20/20
Costa E, Rossi T, Santos M | PROSPERO
8/20/20
Churchill R, Riadi I, Kervin L, et al. | Research Square
8/20/20
Anieto EM, Ogdobo V, Nwadilibe IB, et al  | Research Square
8/20/20
Okullo A, Katairo T, Nalugoda F, et al  | PROSPERO
8/20/20
Wilkinson R, Hines L, Holland A, et al  | PROSPERO
8/20/20
Flodgren G, Bruberg K  | PROSPERO
8/20/20
Sarma P, Bhattacharyya A, Kaur H, et al  | PROSPERO
8/20/20
Huntley B, Chauhan S, Berghella V, et al  | PROSPERO
8/20/20
Lim ZJ, Afroz A, Reddy M, et al  | PROSPERO
8/20/20
Dai M, Li X, Zhang Q | PROSPERO
8/20/20
Chatterji M, Kitamura K, Muenig P, et al  | PROSPERO
8/19/20
Lian R, Gao Y, Zhang R, et al. | Research Square
Aim: To analyze research collaboration, interventions, and outcomes in registered SRs of TCM associated with COVID-19.
8/19/20
Khan DS, Lassi Z, Das J, et al  | PROSPERO
8/19/20
Bancej C | Public Health Agency of Canada
8/19/20
Chang R, Elhusseiny KM, Yeh Y, et al. | medRxiv
Aim: To review the evidence on COVID-19 intensive care unit (ICU) patient characteristics, rates and risks of invasive mechanical ventilation (IMV) and associated outcomes.
8/19/20
Klugar M, Riad A, Klugarova J, et al  | PROSPERO
8/19/20
Roshdy A, Saleh AS, Elsayed AS | PROSPERO
8/19/20
Neil-Sztramko S | National Collaborating Centre for Methods and Tools
8/19/20
Neil-Sztramko S | National Collaborating Centre for Methods and Tools
8/19/20
Khan DS, Lassi Z, Das J, et al  | PROSPERO
8/19/20
Su Z, Meyer K, Li Y, et al. | Research Square
8/19/20
Munhoz I, Lacerda A, Rocha TJM | PROSPERO
8/19/20
Mishra P, Parveen R, Agarwal NB, et al  | PROSPERO
8/18/20
Bhatia R, Gupta S, Bajpai M, et al  | PROSPERO
8/18/20
Yang L, Zhang N, Yun RY, et al  | PROSPERO
8/18/20
Kasemi A, Mohammadi V, Aghababaee SK | PROSPERO
8/18/20
Mahendran S, Amarasekera AT, Malaty M, et al  | PROSPERO
8/18/20
Yu Z, Wang P, Zhuang Y, et al  | PROSPERO
8/18/20
Mbakaya B, Chisale M, Sinyiza F, et al  | PROSPERO
8/18/20
Fernando M, Dharmage S, Lodge C | PROSPERO
8/18/20
Singh S, Khera D, Chugh A, et al | PROSPERO
8/18/20
Yang L | PROSPERO
8/18/20
Greer N, Wilt T, Duan-Porter D, et al  | VA Evidence Synthesis Program
VA ESP
8/18/20
Silverberg J, Goldberg J, Weissman A | PROSPERO
8/18/20
Hoste L, Van Paemel R, Haerynck F | medRxiv
Aim: To perform a systematic review of published cases of this novel multisystem inflammatory syndrome in children associated with COVID-19. 
8/18/20
Yoon SH, Yang S, Cho H, et al  | PROSPERO
8/18/20
Gashaw T, Hagos B, Sisay M | PROSPERO
8/18/20
Marinaki S, Grigorakos K, Boletis I, et al  | PROSPERO
8/18/20
Sahebi A, Adibi A, Pirani D | PROSPERO
8/18/20
Danielli M, Tan B, Hu J | PROSPERO
8/18/20
Rezaei S, Peikanpour M, Dastan F | PROSPERO
8/18/20
Bennis I, Bennis N | PROSPERO
8/18/20
Gonsalves L, Kara E, Broutet N, et al  | PROSPERO
8/17/20
Regalado JA, Tayam MM | PROSPERO
8/17/20
Chatterjee K, Sagar P, Chatterjee R, et al  | PROSPERO
8/17/20
Viana da Silva D, de Jesus Branco SM, Delmiro dos Santos A | PROSPERO
8/17/20
Kawala BA, Kisangala E, Ndagire R, et al  | PROSPERO
8/17/20
Bolaji O | PROSPERO
8/17/20
Hagos B, Gashaw T, Sisay M | PROSPERO
8/17/20
Jafar A, Lasso A, Hutton B, et al  | PROSPERO
8/17/20
Parveen R, Mishra P, Bajpai R, et al  | PROSPERO
8/17/20
Zhan Z, Zhang S, Chen Z | PROSPERO
8/17/20
Varghese A, George G, Sharat VK | PROSPERO
8/17/20
Somagutta MR | PROSPERO
8/17/20
Elsokary M, Elsawah H, Hany A, et al  | PROSPERO
8/17/20
Castillo-Perez M, Jerjes-Sanchez C, Paredes-Vazquez JG, et al  | PROSPERO
8/16/20
Zhang Q, Cao F, Ji G, et al. | Medicine
8/16/20
Yang Y, Zhang D, Zhou C, et al. | BMJ Open
8/15/20
Wang X, Xie P, Sun G, et al | Medicine
8/15/20
Jia H, Han Z, Zhang K, et al. | Medicine
8/15/20
Li M, Fan D, Wang X | Medicine
8/15/20
Zhang X, Cao D, Liu J, et al. | Medicine
CANDIDATE THERAPEUTICS
8/15/20
Wen D, Wu L, Dong Y | Medicine
8/15/20
Zhang Q, Cao F, Ji G, et al. | Medicine
8/15/20
Liang F, Dong L, Zhou L, et al. | Medicine
8/14/20
Tripathy S, Varghese P, Naik M, et al  | PROSPERO
8/14/20
Vilcassim MJR, Callahan A, Zierold K | PROSPERO
8/14/20
Sinaga GHP, Tjoa K, Sutanto RL, et al  | PROSPERO
8/14/20
Li G, Song Z, Xu S, et al  | PROSPERO
8/14/20
Raharja A, Tamara A, Kok LT | medRxiv
Aim: To review the association between ethnicity and poor Covid-19 outcomes including all-cause mortality, hospitalisation, critical care admission, respiratory and kidney failure.
8/14/20
Chen Y, Jiang X | PROSPERO
8/14/20
Hill T, Baker M, Isherwood L, et al. | medRxiv
Aim: To identify putative COVID-19 treatments and identify the roles of immunomodulators and antivirals in disease management. 
8/14/20
Mohanty R, Meher BR, Padhy BM, et al  | PROSPERO
8/14/20
Stavrou M, Solomou S, Ioannou A, et al  | PROSPERO
8/14/20
Moynihan R, Sanders S, Michaleff Z, et al  | PROSPERO
8/14/20
Zhan Z, Zhang S, Chen Z | PROSPERO
8/14/20
Stuijfzand S, Deforges C, Sandoz V, et al. | BMC Public Health
Aim: To synthesize the evidence on the psychological impact of pandemics/epidemics on the mental health of HCPs, what factors predict this impact, and the evidence of prevention/intervention strategies to reduce this impact.
UPDATED
8/14/20
Bhattacharyya A, Sarma P, Kaur H, et al  | PROSPERO
8/14/20
Wu Z, Tang S | PROSPERO
8/14/20
Okwundu JO, Uthman O, Akah OZ | PROSPERO
8/14/20
Neal E, Russell F, Mulholland K | PROSPERO
8/14/20
Bassatne A, Basbous M, Chakhtoura M, et al  | PROSPERO
8/14/20
Asnakew S, Yitabarek GY | PROSPERO
8/14/20
Ao G, Wang Y, Qi X, et al  | PROSPERO
8/13/20
Arevalo Rodriguez I, Buitrago Garcia D, Simancas Racines D, et al.  | medRxiv
Aim: To review and critically appraise evidence about the proportion of RT-PCR false-negatives at initial testing for COVID-19. 
8/13/20
Lim ZJ, Subramaniam A, Reddy M, Jones D, et al  | PROSPERO
8/12/20
Thakkar S, Arora S, Kumar A, et al. | medRxiv
Aim: To provide a foundation for understanding the CV manifestations and outcomes of COVID-19.
8/12/20
Khorramizadeh M, Arab-bafrani Z, Mosavi E | PROSPERO
8/12/20
Chidambaram V, Tun NL, Haque W, et al. | medRxiv
Aim: To determine the demographic, clinical, laboratory and radiological factors associated with severity and mortality in COVID-19.
8/12/20
Sahoo KC, Pati S, Dash GC, et al  | PROSPERO
8/12/20
Chacko J, Brar G, Premkumar R | medRxiv
Aim: To evaluate the efficacy and safety of hydroxychloroquine among patients with COVID 19 infection.
8/12/20
de Oliveira JD, Lago MF, Sarandy MM, et al | PROSPERO
8/12/20
Lim JL, Subramaniam A | PROSPERO
8/12/20
Tunjungputri RN, Tetrasiwi EN, Rizqa T, et al  | PROSPERO
8/12/20
Ramos HMP, Franco ACD, Ronca D, et al  | PROSPERO
8/12/20
Tian Y, Chen H, Xie Y | PROSPERO
8/12/20
Sarkar S, Khanna P, Singh A | PROSPERO
8/12/20
Pickford R, Woeckel M, Schneider A, et al  | PROSPERO
8/12/20
Wells V, Thomas-Meyer M, Gentry S, et al  | PROSPERO
8/12/20
Sarma P, Bhattacharyya A, Kaur H, et al  | PROSPERO
8/12/20
Tractenberg SG, Viola TW, Grassi-Oliveira R | PROSPERO
8/12/20
Neil-Sztramko S, Dobbins M, Anderson L, et al  | PROSPERO
8/11/20
Batra K, Batra R, Sharma M, et al  | PROSPERO
8/11/20
Ismail S, Babonji A, Al Harbi S, et al  | PROSPERO
8/11/20
Honarmand K, Rochwerg B, Siemieniuk R, et al  | PROSPERO
8/11/20
Ayub A, Agarwal N, Mishra S | PROSPERO
8/11/20
Bhamani S, Lassi Z, Rashid M, et al  | PROSPERO
8/11/20
Yin TX, Luo Z | PROSPERO
8/11/20
Heneghan C, Spencer E, Brassey J, et al. | medRxiv
Aim: To identify and evaluate relevant articles (peer-reviewed or awaiting peer review) that examine the mode of viral transmission and ecological variables influencing the mode of transmission.
8/11/20
Campbell J, Bastos M, Perlman-Arrow S, et al  | PROSPERO
8/11/20
Michel S, von Ehrenstein O | PROSPERO
8/11/20
Yang L, Chen X | PROSPERO
8/11/20
Zaki N, Mohamed EA | medRxiv
Aim: To undertake a review and critical appraisal of all published/preprint reports that offer an estimation of incubation periods for novel coronavirus (COVID-19).
8/11/20
Yang J, Chen Y, Tian C, et al  | PROSPERO
8/10/20
Singh P, Pratap S, Bhoil R | PROSPERO
8/10/20
Yang L, Cao S, Huang J | PROSPERO
8/10/20
Sandoval C, Carrasco C, Carrasco D, et al  | PROSPERO
8/10/20
Mozaffari H, Darand M, Raeisi T, et al | PROSPERO
8/10/20
Ma H, Yang L, Guo H | PROSPERO
8/10/20
Necho M, Tsehay M, Belete A | PROSPERO
8/10/20
Henrina J, Pranata R | PROSPERO
8/10/20
Christol RO, Tinica G, Furnica C, et al  | PROSPERO
8/10/20
Sabe M, Dorsaz O, Kaiser S, et al  | PROSPERO
8/7/20
Wang X, Xie P, Sun G, et al | Medicine
8/7/20
Fantin K, Nelson T, Mehdi A | PROSPERO
8/7/20
Li Y, Xu Y, Shi P, et al. | Medicine
8/7/20
Qi M, Jones C, Li P, et al  | PROSPERO
8/7/20
Li R, Li Y, Li B, et al. | Medicine
8/7/20
Patell R, Chiasakul T, Bauer E, et al  | PROSPERO
8/7/20
Sheng Z, Zhang L, Liu X, et al. | Medicine
8/7/20
Henrina J, Pranata R, Lawrensia D, et al  | PROSPERO
8/7/20
Patel K, Huntley C, Mobeen F, et al  | PROSPERO
8/7/20
Shi Y, Wen D, Wang H, et al. | Medicine
8/7/20
Medeiros G, Nunes A, Azevedo K, et al. | Medicine
8/7/20
Abdelaal A, Alkhatip AMM, Kamel MG, et al  | PROSPERO
8/7/20
Li Y, Xu H, Lang H, et al. | Medicine
8/7/20
Khanna P, Sarkar S, Singh A | PROSPERO
8/7/20
Gu R, Xu S, Li Z, et al. | Medicine
8/7/20
Li L, Chen X, Yang W, et al. | Medicine
8/7/20
Vardoulkis S | PROSPERO
8/6/20
Mendes NF, Jara CP, Mansour E, et al. | Research Square
Aim: To review the evidence on the description of asthma as a premorbid condition and its putative association with severe progression of the disease.
8/6/20
Henschke N, Villanueva G, Cogo E | PROSPERO
8/6/20
Wang J, Tang H | PROSPERO
8/6/20
Cui L, Cheng W, Chen M | PROSPERO
8/6/20
Veluri N | PROSPERO
8/6/20
Keegan D, Heffernan E, Masterson S | PROSPERO
8/6/20
AlvesVP, Casemiro FG, de Araujo BG, et al  | PROSPERO
8/6/20
Turner S, Botero N, Nino A, et al  | PROSPERO
8/6/20
Necho M, Belete A, Getachew Y | PROSPERO
8/6/20
Peeters E, Kaur Dhillon Ajit Sing S, Vandesompele J, et al. | medRxiv
Aim: To assess the diagnostic sensitivity of SARS-CoV-2 testing on saliva compared to NP swabs.
8/6/20
Sheng X, Zhou R, Tan Y | PROSPERO
8/6/20
Roshandel E, Kazemi MH, Dehaghi BK, et al. | Research Square
Aim: To explore the possible association of HScore parameters with severity in COVID-19 patients. 
8/6/20
Xu N, Li T, Huang M | PROSPERO
8/6/20
Fernandes N, Antunes M | PROSPERO
8/5/20
Ali R, Al-Jageka C, Bhasin A, et al  | PROSPERO
8/5/20
Li Y, Li J, Zhong D, et al. | Syst Rev
8/5/20
Hoekstra EM, Neumann KMI, Boot PC, et al. | Research Square
Aim: To evaluate the effect of corticosteroids on mortality, viral clearance and secondary outcomes in COVID-19 patients.
8/5/20
da Cunha Sa Caputo D, Coelho de Oliveira AC, Sonza A, et al  | PROSPERO
8/5/20
Zhong Y, Wang K, Zhu Y, et al  | PROSPERO
8/5/20
Liu S, Cao Y, Zhi Y | PROSPERO
8/5/20
de Amaral LC, Calado RD, Teixeira AM, et al. | Research Square
Aim: To map how Lean tools are being used in healthcare and what are their results, including those related to humanization.
8/5/20
Udeh R, Majeed T, Manuel J | PROSPERO
8/5/20
Haile T, Mariye T, Gebremeskel G, et al  | PROSPERO
8/5/20
Khanna P, Sarkar S, Singh A | PROSPERO
8/5/20
Su K, Liu S, Li J, et al  | PROSPERO
8/5/20
Mansuri Z, Sharma K | PROSPERO
8/5/20
Zereabruk K, Aberhe W, Mebrahtom G, et al  | PROSPERO
8/5/20
Aberhe W, Hailay A, Zereabruk K, et al  | PROSPERO
8/5/20
Elsayed HH, Hassaballa AS, Ahmed TA, et al. | Research Square
Aim: To review the evidence on IMV for COVID-associated ARDS to study its outcome among different countries.
8/5/20
Yisak H, Ewunetei A, Teshome F, et al  | PROSPERO
8/4/20
Qian L  | PROSPERO
8/4/20
Patwary MM, Shuvo FK, Dendup T, et al  | PROSPERO
8/4/20
Chi C, Sun J | PROSPERO
8/4/20
Zhang X, Hong T, Lin L | PROSPERO
8/4/20
Cosco TD, Davis D, Conroy S | PROSPERO
8/4/20
Lazarus G, Rinaldi I | PROSPERO
8/4/20
Routhier F, Lebrasseur A, Fortin-Bedard N, et al  | PROSPERO
8/4/20
Capucho H | PROSPERO
8/4/20
Deo KB, Shrestha R, Kumar-M P, et al  | PROSPERO
8/4/20
Thompson CE, Rotta LN, Santos AS, et al  | PROSPERO
8/4/20
Dominic C, Bhalla G, Khare Y, et al  | PROSPERO
8/4/20
Jia N, Sun X, Wang Y, et al  | PROSPERO
8/4/20
Zhang H, Zhang H, Zhang X, et al  | PROSPERO
8/4/20
Kotepui M, Masangkay FR, Kotepui KU, et al  | PROSPERO
8/4/20
Aberhe W, Hailay A, Zereabruk K, et al  | PROSPERO
8/4/20
Hashemimadani N, Emami Z, Janani L, et al. | Research Square
Aim: To assess the relationship between different chest CT features and severity of clinical presentation in COVID-19.
8/3/20
Alves da Silva J, Capucho H | PROSPERO
8/3/20
Moya-Salazar J, Contreras-Pulache H, Moya-Espinoza J | PROSPERO
8/3/20
Miranda ML, Gabbai-Armelin P, Sales LS, et al  | PROSPERO
8/3/20
Perez Y, Li J, Tavernier E, et al  | PROSPERO
8/3/20
Zereabruk K, Aberhe W, Hailay A, et al  | PROSPERO
8/3/20
Furtado S, dos Santos Lucas AC, Basilio Carneiro AL, et al  | PROSPERO
8/3/20
Kyriazopoulou E, Giamarellos-Bourboulis E, Reinhart K, et al  | PROSPERO
8/3/20
Xiong X, Nie R | PROSPERO
8/3/20
Sirois F, Owens J | PROSPERO
8/2/20
Mahdi SS, Ahmed Z, Allana R, et al. | Research Square
Aim: To review all the relevant literate published so far on dental aspects of Covid-19 in order to serve as point of synthesis for future recommendations and guidelines for dental practices. 
8/2/20
Arab-zozani M, Hassanipour S, Ghoddoosi-Nejad D | BMJ Open
8/1/20
Salcher-Konrad M, Jhass A, Naci H, et al. | medRxiv
Aim: To synthesise early international evidence on mortality rates and incidence of COVID-19 among people who use and provide LTC. 
8/1/20
Madewell ZJ, Yang Y, Longini IM, et al. | medRxiv
Aim: To review the evidence on the spread of SARS-CoV-2 by direct, indirect, or close contact with infected people in indoor environments.
8/1/20
Fernandez Villalobos NV, Ott J, Klett-Tammen C | medRxiv
Aim: To review the evidence on the associations between comorbidities and behavioural factors with hospitalisation, Intensive Care Unit (ICU) admission, and death due to COVID-19.
7/31/20
Park M, Pawliuk C, Nguyen T, et al. | medRxiv
Aim: To identify the reported communicable period of SARS-CoV-2.
7/31/20
Szczepura A, Krishnan N, Gumber A, et al  | PROSPERO
7/31/20
Zhang Q, Jiang Y | PROSPERO
7/31/20
Jimenez D, Rali P, Muriel A, et al  | PROSPERO
7/31/20
Lahiri D, Mondal R, Deb S, et al  | PROSPERO
7/31/20
Marzaleh MA, Ghahramani S | PROSPERO
7/31/20
Zhao X, Han G, Gang X | PROSPERO
7/31/20
Almaqbali M | PROSPERO
7/31/20
Darmarkusuma A, Nugroho DB, Chandra LA, et al  | PROSPERO
7/31/20
Browne M, Sing HH, Keith-Jopp CKJ, et al  | PROSPERO
7/30/20
Chivese T, Musa OAH, Hindy G, et al. | medRxiv
Aim: To synthesize the findings presented in systematic reviews and meta-analyses as well as to update the evidence using a meta-analysis in evaluating the efficacy and safety of CQ and HCQ with or without Azithromycin for the treatment of COVID19 infection.
7/30/20
Poudel G, Parsons N, Clohesy R, et al  | PROSPERO
7/30/20
Hu Y, Xiong J, Chen L, et al. | Research Square
Aim: To summarize the existing literature on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in newborns to clarify the clinical features and outcomes of neonates with COVID-19.
7/30/20
Zhao B, Liu K, Lei S, et al. | Research Square
Aim: To investigate the prevalence of elevated troponins in these patients and its prognostic value for predicting mortality.
7/30/20
Chivese T, Musa O | PROSPERO
7/29/20
Maidment I, Young E, Wong G, et al  | PROSPERO
7/29/20
Anderson L, Griffith L, Balion C | PROSPERO
7/29/20
Santos M, Torres D, Cardoso PC, et al. | medRxiv
Aim: To investigate the efficiency of cloth masks in reducing transmission and contamination by droplets and aerosols for the general population and healthcare workers.
7/29/20
Jaber M, Hassan A, AlQahtani F, et al  | PROSPERO
7/29/20
Mao Z, Ong ACM | PROSPERO
7/29/20
Oladimeji K, Dahman NBH, El Shahaway AES, et al  | PROSPERO
7/29/20
Grenet G, Mekhaldi S, Mainbourg S, et al. | medRxiv
Aim: To estimate the effect of DPP4 inhibitors on the risk of respiratory infections.
7/29/20
Menear M, Rice D | Universite Laval
7/29/20
Saez M, Barceli MA, Tobias A, et al  | PROSPERO
7/29/20
Miller J, Lee S | PROSPERO
7/29/20
Gupta A, Ng SM, Mouyis K, et al  | PROSPERO
7/29/20
Tirfe M, Berhane H, Teklu T | PROSPERO
7/29/20
Cevik M, Tate M, Lloyd O, et al. | medRxiv
Aim: To characterise viral load dynamics, duration of viral RNA, and viable virus shedding of SARS-CoV-2 in various body fluids and to compare SARS-CoV-2 viral dynamics with SARS-CoV-1 and MERS-CoV.
7/29/20
Gupta A, Ng SM, Mouyis K, et al  | PROSPERO
7/29/20
Siegel A | PROSPERO
7/29/20
Mayr V, Anna G, Gartlehner G, et al. | Research Square
Aim: To determine the frequency of CNS manifestations of COVID-19 (CNS symptoms, acute cerebrovascular disease, and infectious/inflammatory CNS diseases) and to summarize the current evidence for direct invasion of the CNS by SARS-CoV-2.
7/28/20
Pearce S, Cruz E, Brickley E, et al  | PROSPERO
7/28/20
A systematic review of the effectiveness of Acceptance and Commitment Therapy (ACT) compared with other psychological therapies in managing grief experienced by bereaved spouses or partners of adults who had received palliative care worldwide | PROSPERO
7/28/20
Mamuye M, Yisake H, Teshome F, et al  | PROSPERO
7/28/20
Hydoub YM, Nour S, Al Zubaidi AM | PROSPERO
7/28/20
Moursi A, Taha SHN, Ramadan A | medRxiv
Aim: To assess the cure rate, duration of hospital stay, radiological progression, clinical worsening, need for mechanical ventilation, the occurrence of side effects, and mortality. 
7/28/20
Coon JT, Whear R, Abbott R, et al  | PROSPERO
7/28/20
Pasin L, Landoni G | PROSPERO
7/28/20
Isaacs Z, Guinness L | PROSPERO
7/28/20
Alam MA, Patwary MM, Hossain MR, et al  | PROSPERO
7/28/20
Jomaa MK, Srour S, Geng Y, et al  | PROSPERO
7/28/20
Liu H, Yang D, Zou Y, et al  | PROSPERO
7/28/20
Ma Q, Wu L, Yang Z, et al  | PROSPERO
7/28/20
Qin Q, Chen B, Wang Y, et al  | PROSPERO
7/28/20
Alexandrina de Araujo T, Ferreira de Moura R, Oliveira de Almeida N | PROSPERO
7/28/20
Kiyumi MA, Kalhan A | PROSPERO
7/27/20
Tan RQ, Li WTV, Shum W, et al. | Research Square
Aim: To conduct a systematic review and meta-analysis of peer-reviewed articles, which described clinical data of smell disturbances and OD in COVID-19 patients.
7/27/20
Sales-Peres S, Azevedo-Silva L, Sales-Peres M | PROSPERO
7/27/20
Sardar S, Sharma R, Elshafei MN, et al  | PROSPERO
7/27/20
Syangtan G, Bista S, Dawadi P, et al. | Research Square
Aim: To appraise the burden of asymptomatic individuals and estimate their occurrence among different age groups and gender by reviewing the existing published data on asymptomatic people with COVID-19.
7/27/20
Mohamed MA, Cheng C, Xiang W | PROSPERO
7/27/20
Prado PAB, Vasquez AAH, Comande D, et al  | PROSPERO
7/27/20
Parry M, Bjornnes AK, Nickerson N, et al. | CIHR IRSC
Aim: To determine what is known about the mental health and wellbeing of family caregivers during communicable disease outbreaks.
7/27/20
Babata KL, Yeo KT, Chan CS, et al. | Cochrane Database of Systematic Reviews
7/27/20
Sales-Peres S, Azevedo-Silva L, Castilho AV, et al  | PROSPERO
7/27/20
Chan CS, Kong JY, Babata KL, et al. | Cochrane Database of Systematic Reviews
7/27/20
Goncalves PM, Cuccarese VHE, Cabrera AAC | PROSPERO
7/27/20
Desse TA, Barhane AM | PROSPERO
7/27/20
Zhang G | PROSPERO
7/27/20
Koizumi T, Sugimoto K, Ohnota S, et al  | PROSPERO
7/27/20
Huang X, Huang P, Zheng J, et al  | PROSPERO
7/27/20
Bayley H, Ayabina D, Hollingsworth TD | PROSPERO
7/25/20
Juneau CE, Briand AS, Pueyo T, et al  | medRxiv
Aim: To examine contact tracing effectiveness in the context of COVID-19.
7/25/20
Liu D, You Y, Chen Y, et al. | Medicine
7/25/20
Karimzadeh S, Bhopal R, Nguyen HT | Preprints
Aim: To review the literature on SARS-CoV-2 viral dynamics and their correlation with outcome.
7/24/20
Ghotme KA, Barragan LA, Guerrero JI, et al  | PROSPERO
7/24/20
Demis A, Getie A, Gedefaw, et al  | PROSPERO
7/24/20
Weeks R, Limaye R, Wahl B, et al  | PROSPERO
7/24/20
Van de Sande DGMM, Van Genderen ME, Huiskens J, et al  | PROSPERO
7/24/20
Tripathy S, Varghese P, Panda BB, et al | PROSPERO
7/24/20
Gomes Z, Aithal S, Antonipillai V, et al  | PROSPERO
7/24/20
Dobbins M | National Collaborating Centre for Methods and Tools
7/24/20
Cheruiyot I, Sehmi P, Ngure B, et al  | PROSPERO
7/24/20
Stephenson A, Howes S, McDonough S, et al  | PROSPERO
7/24/20
Fathalipour M, Noormandi A, Hassanipour S | PROSPERO
7/24/20
Schneider J, Gibson B, Talamonti D, et al | PROSPERO
7/24/20
Lee Y, McIntyre R | PROSPERO
7/24/20
Gyanpuri V, Dhiman N, Pathak A, et al. | Research Square
7/24/20
Niburski K, Yan LR, Mamane S | PROSPERO
7/23/20
Yigezu A, Mengistu M, Mikuzie A | Research Square
Aim: To systematically review economic evaluation of interventions to respond to coronavirus pandemics in the global perspective.
7/23/20
Chambergo-Michilot D, Branez-Condorena A, Martinez-Rivera RN, et al | PROSPERO
7/23/20
Shukla P, Tiwari A, Ghosh A, et al  | PROSPERO
7/23/20
Wu G, Jiang P, Yuan H, et al. | Research Square
Aim: To evaluate the efficacy of N95 respirators and medical masks for protection against respiratory infectious diseases, including COVID-19.
7/23/20
Yuan X, Dongmei W, Mingying L, et al  | PROSPERO
7/23/20
Thrinuavukkarasu S, Tapp R, Tina Cao | PROSPERO
7/23/20
Shaheed CA, Beardsley J, Saxena M, et al  | PROSPERO
7/23/20
Bzeizi K, Abdulia M, Mohammed N, et al. | Research Square
Aim: To assess the available evidence on the clinical effects of SARS-CoV-2 on liver function laboratory tests and coagulation profile in affected individuals. 
7/23/20
Sasongko TH, Kademane K, Cummins A, et al  | PROSPERO
7/23/20
Bae S, Kim SR, Park SM, et al  | PROSPERO
7/23/20
Santos J, de Holanda Agostinho AY, Ferreira Soares M, et al  | PROSPERO
7/23/20
Neria Espejo CA, da Silva Pedroso J, de Souza Godinho RC, et al  | PROSPERO
7/23/20
Diallo A, Diallo MH | PROSPERO
7/23/20
Thompson H, Mousa A, Dighe A, et al  | PROSPERO
7/23/20
Ali MM, Dahri M, Shrestha S, et al  | PROSPERO
7/23/20
Bolenta MT, Khatib Z, Asamoah BO, et al  | PROSPERO
7/23/20
Schmidt R, Genois R, Jin J, et al  | PROSPERO
7/23/20
Glendari G, Mangkuliguna G | PROSPERO
7/23/20
Mangkulinguna G, Glendari G | PROSPERO
7/23/20
Sugita B, Marchi R, Centa A, et al  | PROSPERO
7/23/20
Nurdiati D, Atthobari J, Nugroho D, et al  | PROSPERO
7/22/20
Fu Y, Zihan Y, Hanzhou L, et al  | PROSPERO
7/22/20
Qian K, Wang G, Peng H, et al. | Research Square
Aim: To review the evidence on the medical and clinical characteristics of the COVID-19 pandemic in China.
7/22/20
Strudwick G, Sockalingam S, Crawford A, et al. | CIHR IRSC
Aim: To review the evidence related to digital interventions that can be leveraged by the general population to support mental health during and after COVID-19.
7/22/20
Zhang T, Shui M, Zhou Y | PROSPERO
7/22/20
Puyat JH, Ahmad H, Avina M, et al. | CIHR IRSC
Aim: To investigate home-based activities that have protective and therapeutic effects against mental health symptoms during pandemics and to identify if there are activities that are effective for specific groups.
7/22/20
Arentz S, Khamba B, Mravunac M, et al  | PROSPERO
7/22/20
Zhan Q, Fan XJ, Lan YQ | PROSPERO
7/22/20
Zhang T, Shui M, Zhou Y | PROSPERO
7/22/20
Maged A, Dahab S | PROSPERO
7/22/20
Morley S, Bollard M | PROSPERO
7/22/20
Natolanda P, Quigley A | PROSPERO
7/22/20
Resende A, Almeida IB, Gomes IA, et al  | PROSPERO
7/22/20
Bethell J, Babineau J, Bretzlaff M, et al. | CMH Initiative
Aim: To review the evidence on social connectedness and mental health for residents of long-term care homes during the COVID-19 pandemic.
7/22/20
Zhang G, Yao X, Zhang L | PROSPERO
7/21/20
Sarfraz A, Sarfraz Z, Pervaiz Z, et al  | PROSPERO
7/21/20
Khurana R, Deshpande A, Pandey N, et al  | PROSPERO
7/21/20
Kanjanabuch T, Pongpirul K, Nopsopon T, et al  | PROSPERO
7/21/20
Souresrafil A, Rezapour A | PROSPERO
7/21/20
Sadeghi Z, Bahramnezhad F, Javadinejad M, et al  | PROSPERO
7/21/20
Wood F, Roe T, Newman J, et al  | PROSPERO
7/21/20
Zhou P, Zhao R, Zhang Y, et al  | PROSPERO
7/21/20
Grimani A, Bonell C, Michie S, et al  | PROSPERO
7/21/20
Aslam MS, Kim YJ, Qian L  | PROSPERO
7/21/20
Dhouib W, Ayouni I | PROSPERO
7/21/20
Zhong BL | PROSPERO
7/21/20
Wang Z, Xie J, Jiang M, et al  | PROSPERO
7/21/20
Hugo de Oliveira VH, de Albuquerque Filho JB, Morais de Azevedo KP, et al  | PROSPERO
7/20/20
Parashar S, Karthik AR, Gupta R | PROSPERO
7/20/20
Zheng X, Li Y, Yue P, et al  | PROSPERO
7/20/20
Keikha M, Kelishadi R, Akbari N, et al  | PROSPERO
7/20/20
 | VA Evidence Synthesis Program
VA ESP
7/20/20
Hokama P, Hojama NK, Nunes-Nogueira V | PROSPERO
7/20/20
Eketunde A, Adeosun A, Lawal O, et al  | PROSPERO
7/20/20
Videla A, Casetta B, Gospodinoff N, et al  | PROSPERO
7/20/20
Thomas B, Pallivalapila A, El Kassem W, et al. | Syst Rev
7/20/20
Veazie S, O'Neil M, LaFavor B, et al  | PROSPERO
7/20/20
Barth de Castro AC, Parlow JM, Martins CM, et al  | PROSPERO
7/20/20
Esmaeili M, Abdi F, Shafiee G, et al. | Research Square
Aim: To systematically review and pool all available evidence on the olfactory and gustatory dysfunction in COVID-19 patients. 
7/20/20
Li YC, Tu YK | PROSPERO
7/20/20
Wang C, Xaio S, Sun Y, et al. | Research Square
Aim: To examine the impact of respiratory infectious disease pandemics in the new millennium on mental health, behavioral responses, and parenting practices in children, and provide further intervention directions to mitigate negative effects of the 2019 novel coronavirus disease (COVID-19).
7/20/20
Zhang X, Bai H, Ji Y, et al  | PROSPERO
7/20/20
Fernandez Villalobos NV, Vanella P, Lange B | PROSPERO
7/20/20
Zhang G, Qi X, An Y | PROSPERO
7/20/20
Pizarro AB, Carrasco C, Couve C, et al  | PROSPERO
7/17/20
Sanderson K, Porter B | PROSPERO
7/17/20
Ozoya O, Arinze N, Adeosun A, et al  | PROSPERO
7/17/20
Ali AF, Elsaid M, Tawfik GM, et al  | PROSPERO
7/17/20
Zuercher SJ, Adamus C, Philipp K, et al  | PROSPERO
7/17/20
Sarasmitha MS, Larasanty LPF, Chen HY | PROSPERO
7/16/20
Ramasamy A, Prithviraj M, Mohanraj PS | PROSPERO
7/16/20
Ojha V, Verma M, Pandey NN, et al  | PROSPERO
7/16/20
Helvaci N, Eyupoglu ND, Karabulut E, et al  | PROSPERO
7/16/20
Maitra S, Behera S, Gouri M, et al  | PROSPERO
7/16/20
Williams V, Dash N, Suthar R, et al  | PROSPERO
7/16/20
Hoogenes B, Queree M, Townson A, et al  | PROSPERO
7/16/20
Khattab EM, Mahmoud MH, Tawfik GM, et al  | PROSPERO
7/16/20
Zhu F, Zhang M, Gao M, et al. | BMJ Open
7/16/20
Zhang Q, Xu X, Sun S, et al. | Medicine
7/16/20
Liu FS, Liu J, Sun C, et al  | PROSPERO
7/16/20
Frampton L, Learmonth Y, Heritage B, et al  | PROSPERO
7/16/20
Wang Y, Zhu K, Huo P, et al  | PROSPERO
7/16/20
Huang K, Chang C, Shu C | Medicine
7/16/20
Reilly A, Rogers T, Bergin C, et al  | PROSPERO
7/16/20
Pourdehghan P, Mostafavi SA, Mohammadi MR | PROSPERO
7/16/20
Zhou K, Dong S, Fu G, et al | Medicine
7/15/20
Batra K, Pal Singh T, Sharma M, et al  | PROSPERO
7/15/20
Rada G, Burdiles P, Quinelen E, et al  | PROSPERO
7/15/20
Moody E | Dalhousie University
7/15/20
Byambasuren O, Dobler CC, Bell K, et al. | medRxiv
Aim: To estimate the range of valid seroprevalence rates of SARS-CoV-2 in different populations, and compare these seroprevalence estimates with the cumulative cases seen in the same population.
7/15/20
Arinze N, Lawal O, Adeosun A, et al  | PROSPERO
7/15/20
 | CADTH
7/15/20
Shekhar R, Chourasia PK  | PROSPERO
7/15/20
Matos de Abreu A, Roehrs H, Belo C, et al  | PROSPERO
7/15/20
Arce S, Lai S | PROSPERO
7/15/20
Labarca G, Jorquera J, Dreyse J, et al  | PROSPERO
7/15/20
Silveira R, Braga F, Menegueti M, et al  | PROSPERO
7/15/20
Lahiri D, Mondal R, Deb S, et al  | PROSPERO
7/15/20
Sawaogo W, Haile M, Adera T | PROSPERO
7/15/20
 | CADTH
7/15/20
Lin H, Du XR | PROSPERO
7/14/20
Hannah J, Ali SS, Galloway J, et al  | PROSPERO
7/14/20
Sadiq F, Ain Q, Awais S, et al  | PROSPERO
7/14/20
Boregowda U, Perisetti A, Nanjappa A, et al. | medRxiv
Aim: To compare the efficacy of tocilizumab in severe COVID-19 cases vs. standard of care alone.
7/14/20
Mallett S, Allen J, Graziadio S, et al. | medRxiv
Aim: To examine at what time points during SARS?CoV?2 infection it is detectable at different anatomical sites using RT?PCR based tests.  
7/14/20
 | CADTH
7/14/20
Misra DP, Gupta L, Chengappa KG, et al | PROSPERO
7/14/20
Prakash M, Misselwitz B, Padmanabhan S | PROSPERO
7/14/20
Melo A, Lima L, Alves B, et al  | PROSPERO
7/14/20
Dobbins M | National Collaborating Centre for Methods and Tools
7/14/20
Nutarelli S, Cuzzolin M, Filardo G, et al  | PROSPERO
7/14/20
Almeda N, Garcia-Alonso CR, Salvador-Carulla L | Research Square
Aim: To identify, describe and assess the empirical background on online strategies and recommendations developed by international organizations and governments to cope with the psychological impact of COVID-19.
7/14/20
Zafra M, Valencia N, Ortiz M , et al  | PROSPERO
7/14/20
Bonilla-Untiveros C, Camacho S, Baladia E, et al  | PROSPERO
7/14/20
Aquino MRJ, Rankin J, Adamson A, et al  | PROSPERO
7/14/20
 | CADTH
7/14/20
Zhou X, Cheng Z, Dan S, et al  | PROSPERO
7/14/20
Kaye A, Siegel R | medRxiv
Aim: To investigate and synthesize existing evidence for the efficacy of TCZ in reducing COVID-19 mortality.
7/14/20
Dhar R, Sovani M, Kulkarni T, et al  | PROSPERO
7/14/20
 | CADTH
7/13/20
Qu G, Shu L, Song EJ, et al. | medRxiv
Aim: To determine the true effect of ACEI/ARBs use on the risk of infection and clinical outcome of COVID-19.
7/13/20
Sarfraz A, Sarfraz Z, Zia I, et al  | PROSPERO
7/13/20
Wu J, Bourouiba L, McCarthy Z, et al  | PROSPERO
7/13/20
Kong X, Zhang L | PROSPERO
7/13/20
Validababy Z, Lofti M PhD | PROSPERO
7/13/20
Vascocello-Castillo L, Torres-Castro R, Alsina X, et al  | PROSPERO
7/13/20
Sylvester S, Wilcox M, Nicholson S, et al  | PROSPERO
7/13/20
Salifu Y, Maurer P, Oprina E, et al  | PROSPERO
7/13/20
Zhou MC, Liang ZY, Wang R, et al | PROSPERO
7/13/20
Liang X, Chen C, Yang Y | PROSPERO
7/13/20
Zhou Q, Ye S | PROSPERO
7/12/20
Zaki N, Mohamed EA, Ibrahim S, et al. | Research Square
Aim: To assess how common clinical conditions and comorbidities correlate with COVID-19.
7/11/20
Subsoontorn P, Lohitnavy M, Kongkaew C | medRxiv
Aim: To determine the accuracy of nucleic acid point-of-care diagnosis for human coronavirus, particularly, SARS-CoV, MERS-CoV and SARS-CoV-2.
7/10/20
Dhar D, Mondal MS, Rutul s, et al  | PROSPERO
7/10/20
Hessami A, Shamshirian A, Heydari K, et al. | medRxiv
Aim: To study cardiovascular disease burden among COVID-19 patients.
7/10/20
Lenza M, Luongo de Matos L, Marra AR, et al  | PROSPERO
7/10/20
Szako L, Farkas N, Kiss S, et al  | PROSPERO
7/10/20
O'Keeffe J | National Collaborating Centre for Environmental Health
7/10/20
O'Keeffe J | National Collaborating Centre for Environmental Health
7/10/20
O'Keeffe J | National Collaborating Centre for Environmental Health
7/10/20
Cai DB, Zheng W, Yuan WQ | PROSPERO
7/10/20
Santa L, Prado M, Vedovatto M, et al  | PROSPERO
7/10/20
Latha T, Rao A, Bhageerathy R, et al  | PROSPERO
7/10/20
Yang Y, Zhang K, Cai Z | PROSPERO
7/10/20
He B, Shen M  | PROSPERO
7/10/20
Arieta-Miranda J, Alcaychahua ABS, Santos GMP, et al  | PROSPERO
7/10/20
Edington F, Santiago M, Gadelha S | PROSPERO
7/10/20
Duarte Anselmi G, Ortiz-Muñoz LE, Morales Ferrer MB, et al. | OSF
7/10/20
Zace D, Hoxhaj I, Orfino A, et al  | PROSPERO
7/10/20
Li G, Xu Y, Yang YT, et al. | BMJ Open
7/10/20
Guido M, Banchelli F, D'Amico R, et al  | PROSPERO
7/9/20
Saha S, Saha S | PROSPERO
7/9/20
Antwi HA | Research Square
Aim: To establish the driving dynamics of healthcare in CSR engagement, identify its contribution to theory and practice and predict the future pattern as corporate enterprises navigate new CSR strategies through the epochal challenges presented by COVID-19
7/9/20
Gerogiopoulous G, Castiello T | PROSPERO
7/9/20
Milby K, Guedes de Melo AK | PROSPERO
7/9/20
Al Wattar BH, Zaman T, Eames S, et al  | PROSPERO
7/9/20
Souza A, Linhares P, Cobucci R, et al  | PROSPERO
7/9/20
Cascino F, Hoxhaj I, Zace D, et al  | PROSPERO
7/9/20
Saucedi NB, Ramos AC, Alarcon AV, et al  | PROSPERO
7/9/20
Xiong X, Fritzche K, Leonhart R, et al  | PROSPERO
7/9/20
Moore A, Nakahata M, Kalinich C, et al | PROSPERO
7/8/20
Prendki V, Tau N, Avni T, et al. | Research Square
Aim: To examine the participation of elderly patients in therapeutic or prophylactic trials on COVID-19.
7/8/20
Zhang B, Zhang K, Tang Q, et al. | Medicine
7/8/20
Singhal S, Kumar P, Singh S, et al. | Research Square
Aim: To review the evidence on the clinical characteristics of older COVID-19 patients.
7/8/20
Riera R, Bagattini A, Pachito D, et al  | PROSPERO
7/8/20
Isaza ER, Camacho AFV, Pinilla ND, et al  | PROSPERO
7/8/20
Fan W, Liu X | Medicine
7/8/20
Martins L, de Freitas Costa R | PROSPERO
7/8/20
Nearchou F, Flinn C, Hennessy E, et al  | PROSPERO
7/8/20
Routhier F, Lebrasseur A, Fortin-Bedard N, et al  | PROSPERO
7/8/20
Lee MH  | PROSPERO
7/8/20
Alamer A | PROSPERO
7/8/20
Lowry E, Taddese H, Bowman LR | medRxiv
7/8/20
 | CADTH
7/8/20
Lee MH | PROSPERO
7/8/20
Ahmed Z, Desai N | PROSPERO
7/8/20
Park R, Lee S, Kim SY, et al  | PROSPERO
7/8/20
Yang Y, Zhong W, Tian Y, et al. | Medicine
7/8/20
Ow ZGW, Ng CH | PROSPERO
7/8/20
Thornton G, Zhong L, Fleck B, et al  | PROSPERO
7/8/20
Almutairi E, Al-Jaffer M, Alfaifi N, et al  | PROSPERO
7/8/20
Bangpan M, Kulophas D, Shi Y, et al | PROSPERO
7/8/20
Korang SK, Juul S, Nielsen EE, et al | Research Square
7/8/20
King'ori P, Mogire R, Mutua A, et al  | PROSPERO
7/7/20
Pasin L, Landoni G | PROSPERO
7/7/20
Muller A | PROSPERO
7/7/20
Wu J, Zheng Y, Li L | PROSPERO
7/7/20
Sudalaimuthu M, Sekhar S, Saravanan E | PROSPERO
7/7/20
Wang Y, Zhang Y, Liu Y, et al  | PROSPERO
7/7/20
Biswas M, Kali SK | Research Square
Aim: To assess aggregated risk by investigating the association of ACEIs/ARBs users against non-users of ACEIs/ARBs with the risk of mortality or severe clinical manifestations or magnitude of SARS-CoV-2 test positivity in COVID-19 patients.
7/7/20
Fang Z, Yi F, Wu K, et al  | PROSPERO
7/7/20
Dickson K, Sutcliffe K, Bangpan M, et al  | PROSPERO
7/7/20
Putera I, La Distia Nora R, Sitompul R, et al  | PROSPERO
7/7/20
Souza-SIIva G, Mol M, Ceccato M, et al  | PROSPERO
7/7/20
Shrestha DB, Pudhathoki P, Khadka S, et al. | Research Square
Aim: To assess the role of hydroxychloroquine with/without macrolide in terms of efficacy and adverse effects against the standard of care.
7/7/20
Dalia T, Lahan S, Ranka S, et al. | medRxiv
Aim: To delineate the influence of various cardiac conditions (especially CHF) on outcomes of patients with COVID-19 and to determine the prognostic value of cardiac biomarkers.
7/7/20
Nunes JPL | medRxiv
Aim: To perform a systematic review on mortality associated to the use of ACEi in patients with Covid 19 disease. 
7/7/20
Huang J, Wu X, Lv Z | PROSPERO
7/7/20
Sarti T, Lazarini WS, Fontenelle LF, et al. | medRxiv
Aim: To analyze empirical studies on the effectiveness of PHC organization strategies in the context of epidemics to improve access and reduce morbidity and mortality.
7/7/20
Dong S, Zhou K, Fu G, et al  | PROSPERO
7/7/20
Hintermeier M, Bozorgmehr K, Kajikhina K, et al  | PROSPERO
7/7/20
Jammu A, Chasen M, Lofters A, et al | PROSPERO
7/7/20
Dong S, Zhou K, Fu G, et al  | PROSPERO
7/7/20
Whelan G, Sim J, Smith B, et al  | PROSPERO
7/6/20
Gallo DR, Lourdes AS, Carlos R | PROSPERO
7/6/20
Pradhan RR, Yadav AK, Mandal S | Research Square
Aim: To summarize the cardiovascular implications of COVID-19. 
7/6/20
Kumar A, Leite AF, Perrsuad P, et al  | PROSPERO
7/6/20
Octavius GS, Silviani FR, Lesmanadjaja A, et al  | PROSPERO
7/6/20
Souza-SIIva G, Mol M | PROSPERO
7/6/20
Fricke LM, Glockner S, Dreier M, et al  | PROSPERO
7/6/20
Patralekh MK, Jain V, Iyengar K, et al  | PROSPERO
7/6/20
Hannum ME, Ramirez VA, Lipson SJ, et al. | medRxiv
Aim: To provide a comprehensive assessment of methodologies currently employed to quantify smell loss in COVID-19–positive patients and examine whether method type affects reported prevalence of smell loss in COVID-19 patients.
7/6/20
Naskar C, Niyogi S | PROSPERO
7/6/20
Ssentongo P, Heilbrunn ES, Ssentongo A, et al. | medRxiv
Aim: To conduct a systematic review and meta-analysis of the prevalence of HIV in patients hospitalized for COVID-19 and delineating clinical outcomes including mortality.
7/6/20
Mondal MS, Dhar D, Dey T, et al  | PROSPERO
7/6/20
Li Y, Wang P, Ding W, et al  | PROSPERO
7/6/20
Dabbagh R, Jamal A, Temsah MH, et al  | PROSPERO
7/6/20
Pati S, Sahoo KC, Verma P, et al  | PROSPERO
7/5/20
Chaudhari PK, Dhingra K, Zere E, et al  | PROSPERO
7/5/20
Moore AJ, Nakahata MI, Kalinich CC, et al. | medRxiv
7/4/20
Muller AE, Hafstad EV, Himmels JPW, et al. | medRxiv
Aim: To identify, assess and summarize available research on the mental health impact of the covid-19 pandemic on healthcare workers.
7/3/20
Saha S, Saha S | PROSPERO
7/3/20
Landoni G, Cavalli G, Pasin L | PROSPERO
7/3/20
Starke KR, Seidler A, Seidler L | PROSPERO
7/3/20
Katagirya E, Sande O, Heilbrunn E, et al  | PROSPERO
7/3/20
Acharya P, Nair D | PROSPERO
7/3/20
Meka S, Ganesh GB, Bhaskar P, et al  | PROSPERO
7/3/20
Wang Y, Yuan d, Zhang H, et al  | PROSPERO
7/3/20
Dong S, Zhou K, Fu G, et al  | PROSPERO
7/3/20
Dong S, Zhou K, Fu G, et al  | PROSPERO
7/3/20
da Silva Junior FJG, Silva Sales JCE, de Souza Monteiro CF, et al. | BMJ Open
7/3/20
Jung R, Di Santo P, Clifford C, et al. | medRxiv
Aim: To systematically evaluate the quality of reporting of currently available COVID-19 studies compared to historical controls.
7/3/20
Lant S, Civindini S, Singh B, et al  | PROSPERO
7/3/20
Stockwell S, Trott M, Smith L, et al  | PROSPERO
7/3/20
Arroyo-Sanchez A, Chirinos MFM, Egusquiza TM, et al | PROSPERO
7/3/20
Yoon SH, Suh YJ | PROSPERO
7/3/20
Riera R, Pacheco R, Martimbianco A, et al  | PROSPERO
7/3/20
La-Rotta EG, Erazo-Chaves L, Gomez-Larrota HL, et al | PROSPERO
7/3/20
Williams M, Waterson H | PROSPERO
7/3/20
Longchamp G, Longchamp A, Blondon M, et al  | PROSPERO
7/2/20
Toomey E, McSharry, Noone C | OSF
Aim: To review the evidence on accurately communicating risk to maximise adherence to public health preventive measures, while minimising negative impact on psychological outcomes (e.g. mood, mental health) within the general public.
7/2/20
Price L, Butcher J, Gozdzielewska L, Kalule A, et al  | PROSPERO
7/2/20
Scquizzato T, Lembo R, Fominskiy E, et al  | PROSPERO
7/2/20
Roberts A, Rogers J, Sharman S | PROSPERO
7/2/20
Samuel K, Chen K  | PROSPERO
7/2/20
Gerayeli FV, Bae A, Choi L | PROSPERO
7/2/20
Tambala F, Chorwe G, Kululanga L, et al  | PROSPERO
7/2/20
Zhou K, Dong S, Fu G, et al  | PROSPERO
7/2/20
Dong S, Zhou K, Fu G, et al  | PROSPERO
7/2/20
von Borries R, Lowe R, Soeiro D | PROSPERO
7/2/20
Sampieri C, Montero H | PROSPERO
7/2/20
Frazer K, Mitchell L, Stokes D, et al  | PROSPERO
7/2/20
Gedefaw G, Demis A, Waltengus F | PROSPERO
7/1/20
Uphoff E, Lombardo C, Weeks L  | PROSPERO
7/1/20
Abbas Q, Mohsin S, Khan ZA, et al  | PROSPERO
7/1/20
Su Z, Gelfond J, Liang B, et al  | PROSPERO
7/1/20
Castagne B, Emilie G, Resseguier AS, et al  | PROSPERO
7/1/20
Alimoradi Z, Pakpour A | PROSPERO
7/1/20
Sharma VK, Rajak R, Tiwari S | PROSPERO
7/1/20
Zhou K, Dong S, Fu G, et al | Research Square
Aim: To summarize the current evidence of tuina (massage) used as an intervention for pulmonary function in COVID-19 recovering patients.
7/1/20
Dong S, Zhou K, Fu G, et al  | PROSPERO
7/1/20
Alswiahb J | PROSPERO
7/1/20
Pereira C, Vargas D | PROSPERO
7/1/20
Bragazzi NL, Watad A, Bridgewood C, et al  | PROSPERO
7/1/20
Zhou Z, Zhou X, Yu H, et al  | PROSPERO
7/1/20
Wang J, Yang W, Chen P, et al. | Research Square
Aim: To evaluate the proportion and efficacy of corticosteroid use for the treatment of COVID-19.
7/1/20
Dong F, Liu HL, Yang M, et al | PROSPERO
6/30/20
Yamamoto S, Saito M, Nagai H, et al  | PROSPERO
6/30/20
Lee MH | PROSPERO
6/30/20
Cui L, Cheng W | PROSPERO
6/30/20
Low D  | PROSPERO
6/30/20
Roberts A, Rogers J  | PROSPERO
6/30/20
Ayouni I, Dhouib W, Maatoug J, et al  | PROSPERO
6/30/20
Munoz O, Manes C, Alfonso P, et al  | PROSPERO
6/30/20
Wang F, Pan B, Xu S, et al  | PROSPERO
6/30/20
Teoh T, Munro S, Wilcox E | PROSPERO
6/30/20
Qin R, Li J | PROSPERO
6/30/20
Pellegrini L, Fineberg N, Albert U, et al  | PROSPERO
6/30/20
Mingxin W, Mou R, Guo S, et al  | PROSPERO
6/30/20
Khadka S, Budhathoki P, Shrestha DB, et al. | Research Square
Aim: To evaluate the outcome and potential harmful cardiac effects of AZT+HCQ compared to HCQ alone for COVID-19 treatment.
6/30/20
Chen L, An S, Yao G, et al. | Research Square
Aim: To provide a systematic review of the literature and meta-analysis on the use of HCQ/CQ with respect to safety and clinical efficacy of these medications.
6/30/20
Hu X-Y, Zhang XW, Zheng RX, et al  | PROSPERO
6/30/20
de Melo Monteiro GQ, Leonidas Gomes AS, Paz Alvarenga MO, et al  | PROSPERO
6/30/20
Li R, Li Y, Sun H, et al  | PROSPERO
6/30/20
Sadhu S, Dandapani SA, Mazumdar D, et al. | medRxiv
Aim: To estimate the prevalence of ocular manifestations and ocular samples polymerase chain reaction (PCR) positivity among COVID 19 patients.
6/30/20
Bartlett C, Garlovsky J | PROSPERO
6/30/20
Ruiyu M, Li X, Guo S, et al  | PROSPERO
6/30/20
Kpozehouen E, Macintyre R, Tan T | PROSPERO
6/30/20
Brainard J, Harrison F, Jones N, et al  | PROSPERO
6/30/20
da Costa KVT, Carnauba ATL, Rocha KW, et al. | Research Square
Aim: To conduct a systematic review with meta-analysis on the treatments for post-viral non-conductive olfactory disorder (NCSD) to be proposed for olfactory disorder in COVID-19.
6/29/20
Weeks L, Stilwell C, Rothfus M, et al | PROSPERO
6/29/20
Wood S, Vaughan M, Pardhan S | PROSPERO
6/29/20
Jacob S, Hammed A, Pang T, et al  | PROSPERO
6/29/20
Schwartzberg L, Lin A, Jorizzo J | PROSPERO
6/29/20
Johanna N, Henrico -, Wangge G | PROSPERO
6/29/20
Sehmi P, Cheruiyot I | medRxiv
Aim: To systematically analyze literature to establish any evidence of live SARS-CoV-2 virus in fecal samples of COVID-19 patients.
6/29/20
Ruiyu M, Xinyao J, Shanqi G | PROSPERO
6/29/20
Buzzachera CF, Bernardes AG, Correale L | PROSPERO
6/29/20
Demis A, Getie A, Gedefaw G, et al | PROSPERO
6/29/20
Chen M, Qin R | PROSPERO
6/29/20
Zha L, Xu Q, Oan L, et al  | PROSPERO
6/29/20
Lee MH | PROSPERO
6/29/20
Deng J | PROSPERO
6/29/20
Emami A, Javanmardi F | PROSPERO
6/26/20
Wilson P, Islam J, Weinbren M, et al  | PROSPERO
6/26/20
Bak A, Wilson P, Islam J, et al  | PROSPERO
6/26/20
Bloomer M, Walshe C | PROSPERO
6/26/20
Purohit P, Tomo S, Kumar PVSN, et al  | PROSPERO
6/26/20
Wang M, Zheng H, Wang X, et al  | PROSPERO
6/26/20
Peters A, Lotfinejad N, Palomo R | PROSPERO
6/26/20
 | CADTH
6/26/20
Rezapour A, Souresrafil A | PROSPERO
6/26/20
Li J, Liao X, Zhou Y, et al  | PROSPERO
6/26/20
Braga M, Machado G, Raggio DP, et al  | PROSPERO
6/26/20
Mondal R, Ganguly U, Deb S, et al. | medRxiv
Aim: To summarise the clinical profile, investigations and radiological findings among patients with SARS-CoV-2 associated meningoencephalitis.
6/25/20
Innes N, Gallagher J, Harris R, et al.  | PROSPERO
6/25/20
Christina Savvides, Siegel R | PROSPERO
6/25/20
Kuan PX, Chan WK, Ooi MH | PROSPERO
6/25/20
Putera D, Gofi A, Wibowo  | PROSPERO
6/25/20
Scattone De Luiz L, Carneiro LG, et al.  | PROSPERO
6/25/20
Stansfield J, Dobbs S, Ghosh S  | PROSPERO
6/25/20
Khan M, Ostlundh L, Karuveetil P, et al  | PROSPERO
6/25/20
Correa C, Franca M, Santos E, et al. | PROSPERO
6/25/20
Al-Moraissi E, Alyahya A | PROSPERO
6/25/20
Bhagavathula AS, Aldhaleei WA | medRxiv
Aim: To summarize the level of KAP about COVID-19 via a systematic review.
6/25/20
Porto EF, Iamonti VC, de Castro AAM, et al. | Research Square
Aim: To carry out a systematic review of what has been published so far on mortality in patients with COVID-19 associated with diabetes comorbidity.
6/25/20
Gedefaw G, Demis A, Waltengus F | PROSPERO
6/25/20
Lira Neto JCG | PROSPERO
6/25/20
Lozano-Lozano M, Lopez-Garzon M, Gonzalez-Santos A, et al. | PROSPERO
6/25/20
Diniz dos Reis P, Barros Ferreira E, Silva Guerra EN, et al.  | PROSPERO
6/25/20
Qiu D, Yan Q, Hu Y, et al.  | PROSPERO
6/25/20
Roethke N, Guenthner L, Stoffers-Winterling J, et al. | PROSPERO
6/25/20
Monsalves MJ, Zuniga B, Saavedra JA, et al. | PROSPERO
6/25/20
Vindrola C, Kesser C, Vera N, et al.  | PROSPERO
6/25/20
Aloona S, Chauhan CK, Mohindra R, et al.  | PROSPERO
6/24/20
Pearce L, Feirrera LC, Foulds J, et al  | PROSPERO
6/24/20
Tibubos AN, Ernst M, Otten D | PROSPERO
6/24/20
Agarwal L, Agarwal A, Madhusudhan KS, et al  | PROSPERO
6/24/20
Salah HM, Candales AL | Research Square
Aim: To examine the current prevalence and mortality of ACI among COVID-19 infected patients.
6/24/20
De Leon Jr. R, Allegrante JP, Kita | PROSPERO
6/24/20
Nasajpour A, Raina JS, Itare VB, et al | PROSPERO
6/24/20
Su Q, Hu J, Lin H, et al. | medRxiv
Aim: To examine the prevalence of cancer among patients with COVID-19 infection and their risks of severe events.
6/24/20
Hulme C, Ebell M, Bentivegna M, et al  | PROSPERO
6/24/20
Chen Y, Chen L | PROSPERO
6/24/20
Cai J, Yang X, Li G, et al | PROSPERO
6/23/20
Patil V, Khunti K, Seidu S, et al  | PROSPERO
6/23/20
Vasco S, Herrera A, Verdesoto C, et al | PROSPERO
6/23/20
Roshdy A, Zaher S | PROSPERO
6/23/20
Chen H, Xie Z, Zhu Y, et al. | Medicine
6/23/20
Carmisciano L, Signori A | OSF Registries
6/23/20
 | Cochrane COVID Rapid Reviews
6/23/20
Chan V, Leow J, Tan WS, et al  | PROSPERO
6/23/20
Lu Z, Lu M, Cao Z | Medicine
6/23/20
Ciswaka H, Hyute F, Mupungu N, et al | PROSPERO
6/23/20
Li J, Liao X, Wang L, et al  | PROSPERO
6/23/20
Predergast N, Shah F, Price C, et al | PROSPERO
6/23/20
Billings J, Ching B, Gkofa V, et al. | medRxiv
Aim: To provide a rapid review and meta-synthesis of qualitative literature describing healthcare workers’ experiences of working on the frontline and their views about psychosocial support, during Covid-19 or comparable pandemics, such as SARS, MERS or Ebola.
6/23/20
Chen X, Laurent S, Onur O, et al | Research Square
Aim: To study the frequency of neurological symptoms and complications in COVID-19 patients in a systematic review of the literature.
6/23/20
 | CADTH
6/23/20
Ortiz-Muñoz L, Morales Ferrer M, Duarte-Anselmi G, et al. | OSF Preprints
Aim: To provide a summary of the evidence available on the the efficacy of the use of gloves in the prevention of COVID-19 disease in healthy population.
6/23/20
Waring S, Giles S | PROSPERO
6/23/20
Craxford S, Marson B, Rollins K, et al | PROSPERO
6/23/20
Chen M, Zhu H | PROSPERO
6/23/20
Mahat RK, Panda S, Vedika R, et al | PROSPERO
6/23/20
Chaufan C, Yousefi N | PROSPERO
6/23/20
Hou Y, Jia Z | PROSPERO
6/23/20
Martinez-Salas A, Navarro-Ruesga I, Muruato-Araiza S, et al | PROSPERO
6/23/20