COVID-19 Evidence Reviews
as of 12/1/20
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Unpublished Reviews
 
= living review
= draft/preprint   |  
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
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12/1/20
Barnett P, Goulding L, Casetta C, et al. | medRxiv
Aim: To conduct an umbrella review of systematic reviews of research literature and evidence-based guidance on remote working in mental health.
RECENTLY UPDATED
11/30/20
Shao G, Huang S, Cui Y, et al. | Medicine
11/30/20
Li J, Yue J, Zhang S, et al.  | Medicine
11/30/20
Ren X, Shi Y, Li G | Medicine
11/27/20
Kumar A, Kulandhasamy M, Prasoon P, et al. | SSRN
Aim: To consolidate the available knowledge of molecular mechanism(s) behind sex-based differences in viral infections.
11/27/20
Niu J, Chen H, Chen K, et al. | Medicine
11/27/20
Romli MH, Cheema MS, Mehat MZ, et al. | BMJ Open
11/27/20
Galanis P, Vraka I, Fragkou D, et al. | medRxiv
Aim: To examine the impact of the COVID-19 pandemic on nurses’ burnout and to identify associated risk factors.
11/27/20
Sheerin D, Abhimanyu A, Wang X, et al. | medRxiv
Aim: To understand the interaction between these diseases by profiling COVID-19 gene expression signatures on RNA-sequencing data from TB-infected individuals.
11/27/20
Jolliffe D, Camargo C, Sluyter J, et al. | medRxiv
Aim: To determine whether vitamin D reduced ARI risk overall, and to evaluate whether effects of vitamin D on ARI risk varied according to baseline 25(OH)D concentration and/or dosing regimen (frequency, dose size, and trial duration).
11/25/20
Clark A, Botham J, McCrone P, et al  | PROSPERO
11/25/20
Zhang N, Yun R, Liu L, et al. | Medicine
11/25/20
Grepin KA, Ho T, Liu Z, et al. | medRxiv
Aim: To review evidence of the effectiveness of travel measures implemented during the early stages of the COVID-19 pandemic in order to recommend change on how evidence is incorporated in the International Health Regulations (2005) (IHR).
11/25/20
Zhang X, Jiao J, Cao J, et al. | Research Square
Aim: To review the evidence on the association between frailty and mortality among COVID-19 patients.
11/25/20
Jolliffe D, Camargo CA, Sluyter J, et al. | medRxiv
Aim: To assess the overall effect of vitamin D supplementation on risk of acute respiratory infection (ARI), and to identify factors modifying this effect.
11/24/20
Sunjaya AP, Allida S, Di Tanna GL, et al  | PROSPERO
11/24/20
Wing Ow ZG, Yi Teo VX, Yang Heng RR | PROSPERO
11/24/20
Jin G, Zhenghao X, Jia Z | PROSPERO
11/24/20
Slamang W, Abdullahi L, Mustafa F, et al  | PROSPERO
11/24/20
Chen YT, Shao SC | PROSPERO
11/24/20
Marques JS, de Oliveura Meneses M, Gomes AT, et al | PROSPERO
11/24/20
Zhang N, Yun R, Liu L | Medicine
11/24/20
Nirmalasari PI, Indriasari R, Salam A | PROSPERO
11/24/20
Wang Y, Huang Q, Zhang C | PROSPERO
11/24/20
Ma J, Wang R, Zheng Z, et al  | PROSPERO
11/24/20
Papotsi E, Giannakoulis VG, Xourgia E, et al  | PROSPERO
11/24/20
Freiberg A, Schubert M, Starke KR, et al  | PROSPERO
11/24/20
Al-Moraissi EA, Abood M, Alasseri N, et al. | medRxiv
Aim: To assess the effectiveness of surgical mask vs respirators for protecting dental health care workers during dental and OMF AGPs surgical procedures. 
RECENTLY UPDATED
11/24/20
Ipekci MA, Buitrago-Garcia D, Meili KW, et al. | medRxiv
Aim: To compare the patterns of scientific publications for SARS-CoV-2 and Zika infections over time.
11/24/20
Emile S, Khan S, Hamid H | PROSPERO
11/24/20
Syed A, Albury C, Mat Lazim NH, et al  | PROSPERO
11/24/20
Sun C, Han T, Ma S, et al  | PROSPERO
11/24/20
Wang Y, Luo G, Chen X, et al. | Medicine
11/24/20
Chuchu Z, Meng Z, Yalei W | PROSPERO
11/24/20
Ford P, Potdar N | PROSPERO
11/24/20
Li J, Feng L, Zhao H, et al. | Research Square
11/24/20
Korang SK, Juul S, Nielsen EE, et al | Syst Rev
11/24/20
Mao G, Fernandes-Jesus M, Ntontis E, et al. | medRxiv
Aim: To review the evidence on the impact of COVID-19 volunteering both at the UK national level and the more local community level?
11/23/20
Zhang N, Yun RY, Liu L, et al.  | Medicine
11/23/20
Latulippe K, LeBlanc A, Gagnon MP, et al  | PROSPERO
11/23/20
Thomas M, Hull J, Song WJ, et al  | PROSPERO
11/23/20
O'Leary T, Zhao Y | PROSPERO
11/23/20
Koutalos A, Ntalouka M, Malizos K, et al  | PROSPERO
11/20/20
Prendki V, Tau N, Avni T, et al. | Research Square
Aim: To examine the participation of elderly patients in therapeutic or prophylactic trials on COVID-19.
11/20/20
Kyriazopoulou E, Giamarellos-Bourboulis E, Kyprianou M, et al  | PROSPERO
11/20/20
Olumade TJ & Uzairue LI | medRxiv
Aim: To conduct a meta-analysis of the clinical characteristics of COVID-19 patients in Africa.
CLINICAL CHARACTERISTICS
11/20/20
Dambha-Miller H, Albasri A, Hodgson S, et al. | BJGP Open
CANDIDATE THERAPEUTICS
11/20/20
Ayorinde A, Ghosh I, Zahair I, et al  | PROSPERO
11/20/20
Evans C, Holmes K, Kazmierczak K | PROSPERO
11/20/20
Akbar MR, Pranata R, Wibowo A | PROSPERO
11/20/20
Chen J, Xie L, Yuan P, et al. | medRxiv
Aim: To determine whether serum vitamin D is independently associated with COVID-19 infection and outcomes in patients with COVID-19.
CLINICAL CHARACTERISTICS
11/20/20
Ganesh A, Randall M | PROSPERO
11/20/20
Meng Z, Yalei W, Chuchu Z | PROSPERO
11/20/20
Dellafiore F, Nania T, Barello S | PROSPERO
11/20/20
Cherak S, Fiest K, Krewulak K, et al  | PROSPERO
11/20/20
Kawaguchi A, Levy M, Jouvet P | PROSPERO
11/20/20
Yunitri N | PROSPERO
11/20/20
Somagutta MR, Pormento MKL, Hamid P, et al. | Research Square
Aim: To assess anakinra's safety and efficacy for treating severe coronavirus disease in 2019 (COVID-19).
RECENTLY UPDATED
11/20/20
Barochiner J & Martinez R | medRxiv
Aim: To determine a possible association between the use of ACEI/ARB and the progression of COVID-19 to severe forms or death.
11/20/20
Bussink-Voorend D, Hulscher M, Huatvast J, et al  | PROSPERO
11/20/20
Koh J, Urbish SS, Pang VJ, et al  | PROSPERO
11/19/20
Xu J, Ma XP, Bai L, et al. | Medicine
Aim: To assess if the effect estimate of any intervention improves the outcomes and safety profile for Severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2).
CLINICAL CHARACTERISTICS
11/19/20
Izcovich A, Siemieniuk R, Bartoszko JJ, et al. | medRxiv
Aim: To provide a summary of the evidence for all drugs used in the treatment of COVID-19.
11/19/20
Islam MS, Barek MA, Aziz MA, et al. | medRxiv
Aim: To evaluate risk factors, the prevalence of comorbidity, and clinical characteristics in COVID-19 death patients compared to survival patients that can be used as a reference for further research and clinical decisions.
11/19/20
Meng Y, Wang J, Wen K, et al. | Research Square
Aim: To present systematic reviews and detailed estimates of the major symptoms of COVID-19, determine the prevalence of serious comorbidities, and assess patient progression via comorbidities, major symptoms and laboratory examination to help severe patients and effectively reduce the mortality of COVID-19 under the condition of limited medical resources.
11/19/20
Li Y, He W | medRxiv
Aim: To review the evidence on the efficacy and safety of different COVID-19 drugs.
11/19/20
Keikha M, Karbalaei M | Research Square
Aim: To review the evidence on the effects of CP on clinical improvement, increase of discharged cases, as well as reducing mortality of infected patients by viruses SARS-CoV-1, MERS-CoV, and SARS-CoV-2.
11/19/20
Marra LP, Matuoka JY, de Oliveira Junior HA | PROSPERO
11/19/20
Barbosa Santana MP, Silva BO, Alves PM | PROSPERO
11/19/20
Bobrovitz N, Arora R, Cao C, et al.  | medRxiv
Aim: To synthesize seroprevalence data to better estimate the burden of SARS-CoV-2 infection, identify high-risk groups, and inform public health decision making.
RECENTLY UPDATED
11/19/20
Espino P, Quincho-Lopez D, Quincho-Lopez A, et al  | PROSPERO
11/19/20
Ferreira Gurgel MV, de Oliveira Gaudencio | PROSPERO
11/19/20
Zhao Y, Yin L | PROSPERO
11/19/20
Born J, Beymer D, Rajan D, et al. | medRxiv
Aim: To review the evidence on medical imaging in COVID-19 and the utility of AI.
11/19/20
Jimenez-Mora MA, Varela AR, Meneses-Echavez JF, et al. | Research Square
11/19/20
Meybohm P, Kranke P, Schmid B, et al  | PROSPERO
11/19/20
Chambergo-Michilot D, Torres-Gomez | PROSPERO
11/19/20
Ackah M | PROSPERO
11/18/20
Banerjee T, Sharma S, Singh A | PROSPERO
11/18/20
AbdelMassih A, Menshawey R, Hozaien R, et al. | Research Square
Aim: To suggest that exercise is an important adjuvant strategy for prevention of re-infection and for development of better protective responses following vaccination.
11/18/20
Verjel C, Delgado O, Arango D, et al  | PROSPERO
11/18/20
Vasconcelos AC, Schuch L, Ferreira L, et al  | PROSPERO
11/18/20
Yalei W, Huaiyu X | PROSPERO
11/18/20
Cunarro-Lopez Y | PROSPERO
11/18/20
Pranata R, Wibowo A | PROSPERO
11/18/20
Zhu Y, Wang F | Research Square
11/18/20
Whiteman E | medRxiv
Aim: To investigate the association between hypertension as an existing comorbidity and mortality in hospitalized patients with confirmed coronavirus disease 2019 (COVID-19)
11/18/20
Davies K, Krogh C | PROSPERO
11/18/20
Kalin A, Javid B, Knight M, et al. | Research Square
Aim: To summarise the literature on the performance of different rapid tests for exertional desaturation.
11/17/20
Hamam O, Goda A, Awad R, et al. | medRxiv
Aim: To build concrete evidence regarding the incidence and mortality of pulmonary embolism (PE) in patients with COVID-19.
11/17/20
Raheman F, Rojoa D, Parekh J, et al  | PROSPERO
11/17/20
Sardinha DM, Lima KVB, Ueno T, et al. | medRxiv
Aim: To investigate the occurrence of cardiovascular complications associated with SARS-CoV-2 infection.
11/17/20
Cosco TD, Best J, Bryden D, et al. | medRxiv
Aim: To quantify the association between frailty and COVID-19 in relation to mortality in hospitalised patients.
UPDATED
11/16/20
Zhang S, Chen J, Li P, et al  | PROSPERO
11/16/20
Wang Z, Zhang J, Du D, et al. | Medicine
11/16/20
Deng G, Zeng F, Deng Y, et al  | PROSPERO
11/16/20
Wu S, Zhou Q, Zeng X, et al. | Research Square
Aim: To evaluate comparative efficacy and safety of pharmacological interventions in patients with coronavirus disease 2019.
UPDATED
11/16/20
Zhou H, Chen D, Zhang Y, et al. | Medicine
11/16/20
Prabhu P, Parmar A | PROSPERO
11/16/20
Egglestone R, Pappachan JV, Cumpstey AF, et al  | PROSPERO
11/16/20
Chambergo-Michilot D, Barros-Sevillano S, Rivera-Torrejon O | PROSPERO
11/16/20
Russo G, Jesus TS, Deane K, et al  | PROSPERO
11/16/20
Richter D, Riedel-Heller SG, Zuercher SJ | PROSPERO
11/16/20
Lee RA, Herigon JC, Benedetti A, et al. | medRxiv
Aim: To understand the performance of alternative sample types compared to NP swabs
11/16/20
Longchamp G, Manzocchi-Besson S, Longchamp A, et al. | Research Square
Aim: To systematically review and meta-analyze the risk of clinically relevant VTE in patients hospitalized for COVID-19.
UPDATED
11/16/20
Nasrullah SM, Tasnim Z, Hasan | PROSPERO
11/16/20
Arcadepani F, Fidalgo T | PROSPERO
11/16/20
Ollila H, Laine L, Koskela J | PROSPERO
11/16/20
de Souza TA, de Almeida Medeiros A, da Silva Nunes AD, et al  | Medicine
11/16/20
Wang Y, Han L, Zhang W, et al. | Medicine
11/16/20
Liu Y, Fan X, Wang K, et al  | PROSPERO
11/16/20
Kim YJ, Qian L, Aslam MS, et al. | Medicine
11/16/20
Pan D, Sze S, Khunti K, et al  | PROSPERO
11/14/20
Yao J, Chen L, Wang K, et al  | PROSPERO
11/13/20
Rothe M, Rohm E, Mitchell E, et al. | medRxiv
Aim: To review the evidence on hygiene intervention effectiveness against SARS-CoV-2.
11/13/20
Katzenschlager S, Zimmer AJ, Gottschalk C, et al. | medRxiv
Aim: To assess demographic, laboratory and clinical indicators as predictors for severe courses of COVID-19.
UPDATED
11/13/20
Guerrero JI, Barragan LA, Martinez JD, et al. | Research Square
Aim: To describe the features of the central and peripheral nervous system involvement by COVID-19 in terms of pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings.
UPDATED
11/13/20
Chen H, Shi J, Shi W, et al. | BMJ Open
11/13/20
Crowe L, Anderson V, Pugh R | PROSPERO
11/13/20
Vogt F | PROSPERO
11/13/20
Mocellin MC, Curioni C, da Silva Pereira A, et al  | PROSPERO
11/13/20
Lim ZJ, Reddy MP, Shekar K, et al | PROSPERO
11/13/20
Alenezi F, Almeshari M, Olayan L, et al | PROSPERO
11/12/20
Bailey A, Allan D | PROSPERO
11/12/20
Chen CH, Lai CC, Wang CY | PROSPERO
11/12/20
Boonyawat K, Chantrathammachart P, Namthaveg P, et al. | Research Square
Aim: to explore the incidence of venous and arterial thromboembolism among COVID-19 patients requiring hospitalization.
11/12/20
Afroz A, Biliah B, Naher Siddiquea B, Narendra Shetty A, et al  | PROSPERO
11/12/20
Mendonca CR, Naves do Amaral W, Leao de Moraes C | PROSPERO
11/12/20
Rittiphairoj T, Saringkarisate K, Kaewkamjonchai P, et al  | PROSPERO
11/12/20
dos Santos Cordeiro G, Da Aninciacao do Espirito Santo D,  | PROSPERO
11/12/20
Nasrullah SM, Tsnim Z, Hasan MK, et al  | PROSPERO
11/12/20
Gallus S, Lugo A, Clancy L, et al  | PROSPERO
11/12/20
Zhu X, Liu C, Chen Y, et al  | PROSPERO
11/12/20
Puzanian H, Ghezzawi M, El-Habar R, et al  | PROSPERO
11/12/20
Ji Y, Song D, Liu H, Huo H, Cheng Li | PROSPERO
11/11/20
Parker J, Lyness E, Dambha-Miller H, et al  | PROSPERO
11/11/20
Dhivagaran T | PROSPERO
11/11/20
Zhou C, An T, Liu Y, et al  | PROSPERO
11/11/20
Mbakaya B, Chisale M, Kumwenda P, et al  | PROSPERO
11/11/20
Soakaew S, Kanchanasurakit S, Kositamongkol C, et al  | PROSPERO
11/11/20
Bates L, Riley S, Stoner L, et al  | PROSPERO
11/11/20
Zheng YB, Yuan K, Sun YK, et al  | PROSPERO
11/11/20
Qiu G, Qiu F, Chen D, et al  | PROSPERO
11/11/20
Suk JE, Vardavas C, Nikitara K, et al. | medRxiv
Aim: To assess child-to-child and child-to-adult SARS-CoV-2 transmission and to characterise the potential role of school closures on community transmission.
11/10/20
Pereira Linhares FM, Correia de Abreu WJ, de Oliveira Cabral Melo, et al  | PROSPERO
11/10/20
Tomfohr-Madsen L, Silang K, Sohal P | PROSPERO
11/10/20
Durao C, Henriques HR, Costa A, et al  | PROSPERO
11/10/20
Chinnadurai R, Jeyalan V, Ponnusamy A, et al  | PROSPERO
11/10/20
Daniels NF, Burrin C, Chang T, et al  | PROSPERO
11/10/20
Lee B, Boyd L, Ling M, et al  | PROSPERO
11/10/20
Avni T, Yahav D, Leibovici L | PROSPERO
11/10/20
Domne FM, De Lucca Da Silva J, de Alcantara Bonfirm J, et al  | PROSPERO
11/9/20
Ngo BT, Marik P, Kory P, et al. | medRxiv
Aim: To determine the potential time course for development of treatments and vaccines, focusing on availability now and continuing in the last half of 2020. 
11/9/20
Khan F, Stewart I, Fabbri L, et al. | medRxiv
Aim: To systematically review and assess the effectiveness of specific interleukin-1 and -6 inhibitors for the treatment of coronavirus-related infections. 
11/9/20
Chen CH, Wang CY, Lai CC, et al  | PROSPERO
11/9/20
Yu Z, Wang P, Chen B, et al  | Medicine
11/9/20
Alkofide H, Almohaizeie A, Alkharfy K, et al  | PROSPERO
11/9/20
Bai H, Ji Y, Wang J, et al  | Medicine
11/9/20
Kollikonda S, Karnati S, Chavan M | PROSPERO
11/9/20
Graham W, Calvert C, John J | PROSPERO
11/9/20
Li GF, Yu G, An XX, et al  | PROSPERO
11/9/20
Saragih ID | PROSPERO
11/9/20
Barboza J, Castaneda-Sabogal A, Chambergo-Michilot D, et al  | PROSPERO
11/9/20
Liu R, Mou R, Jin X, et al  | PROSPERO
11/9/20
Cordeiro LP, Linhares E, Nogueira FGO, et al. | Research Square
Aim: To review the articles available about the use of GC in patients with COVID-19 and to provide a safer analysis of the effectiveness and recommendations for its use.
11/9/20
Shi J, Gao Y, Zhao L, et al. | Syst Rev
CLINICAL CHARACTERISTICS
11/9/20
Labrague LJ | medRxiv
Aim: To appraise and synthesize studies examining psychological resilience, coping behaviours, and social support among healthcare workers (HWCs) during the coronavirus pandemic.
11/9/20
Cavalcante T | PROSPERO
11/9/20
Amimo F, Lambert B, Magit A, et al. | Research Square
Aim: To review the current evidence on the impact of COVID-19 on HIV, tuberculosis, and malaria across Africa.
11/9/20
Helps S, LeCoyte M | PROSPERO
11/9/20
Duan Y, Ziong M, Wang H, et al. | Medicine
11/9/20
Wang Q, Li M, Zhu H, et al  | PROSPERO
11/6/20
Cantu Alejo DR, Angeles Mar HJ, Arciniega Trevino AM, et al  | PROSPERO
11/6/20
Zahiri J, Afsharinia MH, Hekmati Z, et al. | medRxiv
Aim: To review the most frequently reported imaging features in COVID-19 patients in order to provide a reliable insight into expected CT imaging manifestations in patients with positive reverse-transcription polymerase chain reaction (RT-PCR) test results, and also for the initial detection of patients with suspicious clinical presentation whose RT-PCR test results are false negative.
11/6/20
van Paassen J, Vos JS, Hoekstra EM, et al. | Research Square
Aim: To evaluate the effect of corticosteroids on mortality, viral clearance and secondary outcomes in COVID-19 patients.
11/6/20
Messina A | PROSPERO
11/6/20
Schmeckenbecher J, Rattner K, Kapusta N | PROSPERO
11/6/20
Torres-Sanchez I, Perez-Gisbert L | PROSPERO
11/6/20
Coyle C, Buggy S, Cagney O, et al. | HRB Open Res
11/6/20
Meybohm P, Kranke P, Popp M, et al  | PROSPERO
11/6/20
Alshammary, Alsughayyir J | PROSPERO
11/6/20
Othman F, Ismaeil T | PROSPERO
11/6/20
Mathioudakis AG, Alimani GS, Papadopoulos NG | PROSPERO
11/6/20
Javidnia J, Khojasteh S, Hosseini SA, et al  | PROSPERO
11/6/20
Vijayan R, Sheikh M, Zaidi M, et al | PROSPERO
11/6/20
Dal Curtivo dos Passos J, Borges YS, Guiloski IC | PROSPERO
11/6/20
Blasco-Belled A, Gallardo CT, Alsinet C, et al  | PROSPERO
11/5/20
Vaselli M, Shenton B, Hungerford D, et al  | PROSPERO
11/5/20
Hunter J, Arentz S, Goldenberg J, et al. | medRxiv
Aim: To evaluate the benefits and risks of any type of zinc intervention to prevent or treat SARS-CoV-2.
11/5/20
Kirkland P, Russell M | PROSPERO
11/5/20
Chieng WK, Chong Lau DS, Tan CE, et al  | PROSPERO
11/5/20
Thakur B, Dubey P, Benitez J, et al  | PROSPERO
11/5/20
Santos R, Rego S, Brito L | PROSPERO
11/5/20
Bach-Mortensen A, Verboom B, Esposti MD | PROSPERO
11/5/20
Graf E, Goetz T, Voracek M | PROSPERO
11/5/20
Yuan P, Ai P, Liu Y, et al. | medRxiv
Aim: To summarize reliable medical evidence by the meta-analysis of all published clinical trials that investigated the safety, tolerability, and immunogenicity of vaccine candidates against coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
11/5/20
Zhu X, Liu C, Chen Y, et al  | PROSPERO
11/5/20
Wang G, Hong X, Li J, Zhao M, et al  | PROSPERO
11/5/20
Kallapur AS, Yen EY, Singh RR | medRxiv
Aim: To determine the prevalence of antiphospholipid (aPL), including lupus anticoagulant, anti-cardiolipin and anti-?2-glycoprotein-1 antibodies, and its possible association with thrombotic manifestations of COVID-19. 
11/5/20
Kalin A, Greenhalgh T, Javid B, et al. | medRxiv
11/4/20
Frazer K, Mitchell L, Stokes D, et al  | medRxiv
Aim: To investigate measures implemented in long term care facilities to reduce transmission of COVID-19 and their effect on morbidity and mortality of residents, staff, and visitors. 
UPDATED
11/4/20
Shebab M, Alrashed F, Shuaibi S, et al. | medRxiv
Aim: To evaluate the prevalence of GI, liver function test (LFT) abnormalities, and mortality of COVID-19 patients.
11/4/20
Teixeira JRB, Barreto NMOV, Araujo WAC, et al  | PROSPERO
11/3/20
Reddy MP, Subramaniam A, Lim ZJ, et al  | medRxiv
Aim: To evaluate the impact of prone positioning on oxygenation and clinical outcomes. 
UPDATED
11/2/20
Zhang Y, Ma P, Zhang X, et al. | Medicine
11/2/20
Dhada S, Hadi MH, Cheema E, et al | PROSPERO
11/2/20
Demartini K, Alt L, Secchi J, et al | PROSPERO
11/2/20
Hung KC, Sun CK, Chiang MH | PROSPERO
11/2/20
Reddy S, Satani N, Beauchamp J, et al  | PROSPERO
11/2/20
Zhang Y, Han H, Tian Y, et al. | Medicine
11/2/20
Huntley C, Mughal A, Patel K, et al  | PROSPERO
11/2/20
Mou R, Jin X, Li W, et al. | Medicine
11/2/20
Cao C, Zhen Z, Kuang S, et al. | Medicine
11/2/20
Chen YJ, Deb A, Yang C, et al  | PROSPERO
11/2/20
Montalto C, Pagnesi M, Lupi L, et al  | PROSPERO
11/2/20
Asgarian-Omran H, Rajabinejad M | PROSPERO
11/2/20
Chen D, Zhou H, Yang Y, et al. | Medicine
11/2/20
Yang Y, Chen XFD, Chen Y, et al. | Medicine
11/2/20
Alwan NA, Davis H, Woodrow M, et al  | PROSPERO
11/2/20
O'Donnell E, Haberli J, Dang K, et al  | PROSPERO
10/31/20
Levin AT, Meyerowitz-Katz G, Owusu-Boaitey N, et al. | medRxiv
Aim: To assess the age specificity of the infection fatality rate (IFR) for COVID-19 using seroprevalence results from eight national studies (Belgium, England, Hungary, Italy, Netherlands, Portugal, Spain, and Sweden), fifteen seroprevalence studies of specific locations in Europe and the United States, and three countries (Iceland, New Zealand, and Republic of Korea) that have engaged in comprehensive tracking and tracing of COVID-19 infections.
10/30/20
Shi B, Li X, Luo J | PROSPERO
10/30/20
Khattab EM, Tam DNG, Aryal V, et al  | PROSPERO
10/30/20
Mahamat-Saleh Y, Fiolet T, Aune D | PROSPERO
10/30/20
Sahebi A, Golitaleb M, Nejati B | PROSPERO
10/30/20
Speed T, Letzen J, Mun CJ, et al  | PROSPERO
10/30/20
Li GF, Yu G, An XX, et al  | PROSPERO
10/30/20
Bertini P, Paternoster G | PROSPERO
10/30/20
Chen X, Chen Z, Azman AS, et al. | medRxiv
Aim: To evaluate the quality of serological studies and provide a global picture of seroprevalence across demographic and occupational groups, and to provide guidance for conducting better serosurveys.
10/30/20
Zheng L, Huang Q, Yu N, et al  | PROSPERO
10/30/20
Flannery F, Sheerin F, McCausland D, et al  | PROSPERO
10/30/20
Mangkulinguna G, Glendari G, Natalia N, et al  | PROSPERO
10/29/20
Liu N, Li H | PROSPERO
10/29/20
Gordon A, Sharpe J, Allen K, et al  | PROSPERO
10/29/20
Pranata R, Lim M, Yonas E, et al  | PROSPERO
10/29/20
So M, Copeland A, Zai C, et al  | PROSPERO
10/29/20
Wells V, Pari A, Kuhn I, et al  | PROSPERO
10/29/20
Saikia P, Thakuria B, Thottan R | PROSPERO
10/29/20
Kumar A, Kumari C, Narayan RK, et al  | PROSPERO
10/29/20
Garbern S, Bills C, O'Reilly G, et al  | PROSPERO
10/29/20
Ghosn L, Davidson M, Boutron I | PROSPERO
10/29/20
Moynihan R, Sanders S, Michaleff Z, et al  | medRxiv
Aim: To determine the extent and nature of changes in utilisation of healthcare services during COVID-19 pandemic. 
UPDATED
10/29/20
Musuuza J, Watson L, Parmasad V, et al. | medRxiv
Aim: To examine occurrence of respiratory co-infections and superinfections and their outcomes among patients with SARS-CoV-2 infection.
UPDATED
10/29/20
Emami A, Javanmardi F | PROSPERO
10/29/20
Khoo JY, Constantiou A, Yang C | PROSPERO
10/29/20
Mebrahtom G, Hailay A, Aberhe W, et al  | PROSPERO
10/29/20
Rocha-Filho C, Nunes Pinto ACP, da Rocha AP, et al  | PROSPERO
10/29/20
Pranata R, Henrina J, Lim M, et al  | PROSPERO
10/28/20
Sharma P, Mahajan A, Rane S, et al. | SSRN
Aim: Not provided
10/28/20
Khera D, Chugh A, Khasbage S, et al. | Research Square
Aim: To review the evidence on the correlation between BCG vaccination and COVID-19 cases.
UPDATED
10/28/20
Okoli G, Rabbani R, Copstein L, et al  | PROSPERO
10/28/20
Seong D, Shin J, Kim MS | PROSPERO
10/28/20
Liang W, Shang B, Peiris, et al  | PROSPERO
10/28/20
Mathioudakis AG, Fally M, Hashad R, et al. | medRxiv
Aim: To describe the outcomes evaluated in 415 RCTs on the management of COVID-19.
10/28/20
Bhagavathula AS, Rahmani J | PROSPERO
10/28/20
Baxter S, Blank L, Chambers D, et al  | PROSPERO
10/28/20
Caldeira D, Prada L, Baiao R, et al  | PROSPERO
10/27/20
Aridas A, Sheen J, Reupert A, et al  | PROSPERO
10/27/20
Bhatnagar S, Rijhwani K, Dhokar A | PROSPERO
10/27/20
Jiao LR, An XX, Lu CX, et al  | PROSPERO
10/27/20
Zhou C, Zhang Y, Cao L, et al  | PROSPERO
10/27/20
Shi J, Li Y, Zhao L, et al.  | Research Square
Aim: To provide comprehensive and continuously updated data to explore the prevalence of depression, anxiety, delirium, and post-traumatic stress disorder (PTSD) among COVID-19 patients.
10/27/20
Patanavanich R, Glantz SA  | medRxiv
Aim: To compare the association between smoking and COVID-19 disease progression between unadjusted analyses with adjusted analyses to examine whether smoking is an independent risk factor.
CLINICAL CHARACTERISTICS
10/27/20
Mondal R, Deb S, Shome G, et al.  | medRxiv
Aim: To summarise so far available pieces of evidence documenting SARS-CoV-2 mediated spinal demyelination in terms of clinical, laboratory parameters and imaging characteristics.
CLINICAL CHARACTERISTICS
10/27/20
Feizullayeva C, Katz J, Vialet J, et al  | PROSPERO
10/27/20
Lee M, Kim S, Shin J, et al  | PROSPERO
10/27/20
Lumngwena EN, Njoku KF, Ndibangwa P, et al | PROSPERO
10/27/20
Li F, Lu H, Li X, et al. | Medicine
Aim: To ascertain the association between COVID-19 and intestinal flora that will facilitate management or prevention strategies of COVID-19.
CLINICAL CHARACTERISTICS
10/27/20
Ghasemian R, Shamshirian A, Keydari K, et al. | medRxiv
Aim: To review the evidence on the role of vitamin D in COVID-19.
10/26/20
Tandon M, Mehta TR, Daimee M, et al. | Research Square
Aim: To establish a pattern and understand the significance of CSF analysis which can possibly be useful in deciding prognosis and exploring therapeutic options in the future. 
10/26/20
Patrick K, Pothamsetty N, Tello LY | PROSPERO
10/26/20
Hamam O, Goda A, Eldalal M, et al. | medRxiv
Aim: To build concrete evidence regarding the incidence of cardiac arrhythmia in patients with COVID-19.
10/26/20
Zhang R, Gao Y, Xie D, et al. | Research Square
Aim: To analyze research collaboration, interventions, and outcome measures in registered SRs of treatment associated with COVID-19 and point out the problem.
10/26/20
Williams V, Dash N, Suthar R, et al  | medRxiv
Aim: To synthesize the current data on clinico-laboratory features, intensive care needs, treatment, and outcome of Pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C).
UPDATED
10/26/20
Maciel A, Xavier M, Neto JR, et al | PROSPERO
10/26/20
Treskova M, Haas L, Scholz S, et al  | PROSPERO
10/26/20
Yarandi RB, Panahi MH, Hatami H, et al  | PROSPERO
10/26/20
Richards GC, Khaira TS, Aronson JK, et al | PROSPERO
10/26/20
Yin S | PROSPERO
10/26/20
Regmi K, Lwin C | BMJ Open
10/26/20
Parsons N, Outsikas A, Parish A, et al. | medRxiv
Aim: To quantify the locations of small neurological events identified with magnetic resonance imaging (MRI) among COVID-19 patients.
UPDATED
10/26/20
Kloppenburg J, Singh S, Leftwich H, et al  | PROSPERO
10/26/20
Wu Q, Jiang Y, Zhang M, et al  | PROSPERO
10/26/20
Balakumar S | National Collaborating Centre for Infectious Diseases
10/26/20
Alkofide H, AlOtaibi B, AlMuhaini S, et al  | PROSPERO
10/26/20
Benefield AE, Skrip LA, Clement A, et al. | medRxiv
Aim: To provide pooled time-series distributions of coronavirus viral load and the duration of viral shedding across patient subgroups defined by demographic and clinical characteristics, after controlling for study-specific methodologies.
CLINICAL CHARACTERISTICS
10/26/20
Balakumar S | National Collaborating Centre for Infectious Diseases
10/26/20
Galway R, Swales M, Wane J | PROSPERO
10/23/20
Byambasuren O, Dobler CC, Bell K, et al. | medRxiv
Aim: To estimate the range of valid seroprevalence rates of SARS-CoV-2 in different populations, and compare these seroprevalence estimates with the cumulative cases seen in the same population.
10/23/20
dos Santos Cunha CRS, Belo Fort MPM, Teixeira Pereira PTV | PROSPERO
10/23/20
Hurst J, Porter J, Althobiani M | PROSPERO
10/23/20
Amimo F, Lambert B, Magit A, et al.  | PROSPERO
10/23/20
Riera R, Bagattini A, Pachito D, et al.  | PROSPERO
10/23/20
Elsawah H, Elsokary M, Elshafie A, et al.  | PROSPERO
10/23/20
Ghosn L, Davidson M, Boutron I | PROSPERO
10/23/20
Chan J, Reed A, Lim N, et al.  | PROSPERO
10/23/20
Franceschi Jr VB, Santos Jr AS, Glaeser JR AB, et al. | medRxiv
Aim: To evaluate the qualitative aspects of population-based seroprevalence surveys of COVID-19, including their reliability and biases.
UPDATED
10/23/20
Berhane M, Abate S | PROSPERO
10/23/20
Cares K, Montenegro Y, Torres R, et al.  | PROSPERO
10/23/20
Hajikhani B, Nasiri J, Dadashi M | PROSPERO
10/23/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/23/20
Sehgal A, Orenstein S, Tang K | PROSPERO
10/23/20
Yan C, Sun C, Chen C, et al.  | PROSPERO
10/22/20
Li Y, Liang Y, Xu M | PROSPERO
10/22/20
Adil M, Gaba U, Azharuddin M, et al.  | PROSPERO
10/22/20
Omodan A, Olojede S, Lawal S, et al.  | PROSPERO
10/22/20
James P, Ali Z, Armitage A, et al | medRxiv
Aim: To provide a systematic review of the latest evidence on how malnutrition across all its forms (under- and over-nutrition and micronutrient status) may influence both susceptibility to, and progression and severity of, COVID-19.
UPDATED
10/22/20
Am X, Weng X, Huang Q | PROSPERO
10/22/20
Wang Q, Liu J, Shao R, et al.  | PROSPERO
10/22/20
Golinelli D, Boetto E, Carullo G, | J Med Internet Res
Aim: To describe which digital solutions have been reported in the early scientific literature to mitigate the impact of COVID-19 on individuals and health systems.
10/22/20
da Silva Melo Malaquias T, do Campos Fernandez Lourenco Haddad M, Okubo CVC, et al. | PROSPERO
10/22/20
Diaz LA, Lagos A, Aliaga R, Garcia-Huidobro F, et al.  | PROSPERO
10/22/20
Murthy S, Sterne J, Tritscheler T, et al.  | PROSPERO
10/22/20
Han L, Wang Y, Hu K, et al. | Medicine (Baltimore)
Aim: To propose a systematic evaluation program to evaluate the efficacy and safety of Huashi Baidu Formula combined with antiviral drugs for COVID-19.
10/21/20
Li Y, Liang M, Gao L, et al. | medRxiv
Aim: To evaluate the effectiveness of using face masks to prevent the spread of SARS-CoV-2. 
UPDATED
10/21/20
Urwin SG, Lendrem BC, Suklan J, et al. | medRxiv
Aim: To evaluate the diagnostic accuracy of a commercial POC test (FebriDx) in patients with suspected COVID-19.
10/21/20
Townsend R, Chmielewska B, Khalil A, et al.  | PROSPERO
10/21/20
Roshandel MR, Nateqi M, Lak R, et al. | medRxiv
Aim: To review the evidence on the SARS-CoV-2 infectivity of body fluid.
10/20/20
Romoli M, Baldini T | PROSPERO
10/20/20
de Lourdes Lira A | PROSPERO
10/20/20
Rattka M, Imhof A, Baymhardt M | PROSPERO
10/20/20
Ashour R, Shehawy O, Diab R, et al.  | PROSPERO
10/20/20
Aggarwal S, Sharma M, Madaan P, et al.  | PROSPERO
10/20/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/20/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/20/20
E Silva IES, de Melo MA | PROSPERO
10/20/20
Alizadeh S, Ozgoli G | Research Square
10/19/20
Shi S, Wang Z, Wang F, et al.  | PROSPERO
10/19/20
Costa D, Nutsch N, Duwendag S, et al.  | PROSPERO
10/19/20
Hammoud H, Bendari A, Bendari T, et al. | medRxiv
Aim: To provide a total picture of the SARS-CoV-2 histopathological features of different body organs in postmortem autopsies through a systematic search of the published literature.
10/19/20
Viner RM, Ward J, Hudson L, et al. | medRxiv
Aim: To undertake a systematic review of reviews of the prevalence of symptoms and signs of COVID-19 in those aged under 20 years.
10/16/20
Chen P, Bobrovitz N, Premji Z, et al.  | medRxiv
Aim: To review the evidence on transmissibility of SARS-CoV-2, including mechanistic correlates of overdispersion, viral kinetics, and infectiousness.
UPDATED
10/15/20
Beale S, Hayward A, Shallcross L, et al. | medRxiv
Aim: To review current evidence regarding the asymptomatic proportion of PCR-confirmed SARS-CoV-2 infections based on methodologically-appropriate studies in community settings.
10/15/20
Jenkins D, Paquette M, Sahye-Pudaruth S, et al.  | PROSPERO
10/15/20
Gebremeskel G, Haile T, Gebrewahd G, et al.  | PROSPERO
10/15/20
Atmosudigdo I, Pranata R, Anthonius M, et al.  | PROSPERO
10/15/20
Qi X, Ao G, Wang Y | PROSPERO
10/15/20
Slomka A, Kowalewski M, Zekanowska E, et al.  | PROSPERO
10/15/20
Papapanou M, Papaioannou M, Petta A, et al.  | PROSPERO
10/15/20
Du X, Shi L, Cao W | PROSPERO
10/15/20
Carvalho C, Souza AB, Rego CO, et al. | PROSPERO
10/15/20
Elangovan EJ, Kumar VS, Kathiravan A, et al. | medRxiv
Aim: To evaluate the clinical outcomes of repurposed drugs against COVID-19 including Tocilizumab, Remdesivir, Dexamethasome, Lopinavir-ritonavir, Favipiravir, Hydroxychloroquine, and Convalescent plasma therapy. 
10/15/20
Cavalcante T | PROSPERO
10/15/20
Zhou X, Pan J, Wang H, et al.  | PROSPERO
10/15/20
Kumar J, Meena J, Yadav A, et al.  | PROSPERO
10/15/20
Mittal S, Madan K, Mohan A, et al. | PROSPERO
10/15/20
Zhi Y, Gao C, Qin Y | PROSPERO
10/15/20
Francheska BDK, Wilson E, Oni G, et al. | PROSPERO
10/15/20
Epstein A, Mdgela J | PROSPERO
10/15/20
Xu W, Li X, Dozier M, et al. | medRxiv
Aim: To investigate the extent of SARS-CoV-2 transmission in schools. 
UPDATED
10/14/20
Danjuma , Mahgoub Y, Mushtaq K, et al.  | PROSPERO
10/14/20
Huang F, Song J, Zheng B, et al.  | PROSPERO
10/14/20
Boet S, Etherington N | PROSPERO
10/14/20
Mehendale F, Reynolds D, Clayton G, et al.  | PROSPERO
10/14/20
Roberts M, Driggs D, Thorpe M,et al. | arXiv
Aim: To review the evidence on machine learning methodologies for detection and prognostication of COVID-19 from standard-of-care chest radiographs and computed tomography images.
10/14/20
Shi J, Li Y, Zhao L, et al. | Research Square
10/14/20
Douglas M, Dozier M, McSwiggan E, et al.  | PROSPERO
10/14/20
Qi X, Wu B, Zhu Z, et al.  | PROSPERO
10/14/20
Tadesse DB, Wahdey S, Negash M, et al. | Asthma Res Pract
10/13/20
De Kock JH, Latham HA, Leslie SJ, et al. | Research Square
Aim: To identify whether there are any identifiable risk factors for adverse mental health outcomes amongst HSCWs during the COVID-19 crisis. 
10/13/20
Gonzales-Rayas JM, Jerjes-Sanchez C, Martinez-Magallanes DM, et al.  | PROSPERO
10/13/20
Asiimwe IG, Pushpakom S, Turner R, et al | medRxiv
Aim: To continually evaluate the rapidly evolving evidence base on the role of cardiovascular drugs in COVID-19 clinical outcomes (susceptibility to infection, hospitalization, hospitalization length, disease severity, and all-cause mortality).
UPDATED
10/13/20
Rivero-Santana A, Perestelo-Perez L, Ramos-Garcia V, et al.  | PROSPERO
10/13/20
Nguyen A, Elsaid M, Ghula S, et al.  | PROSPERO
10/13/20
Rocha KO, Zanuncio VV, Lima LM | PROSPERO
10/13/20
Pandey R, Gourishankar A | medRxiv
Aim: To evaluate the diagnostic accuracy of FDA authorized serology tests for the detection of SARS-CoV-2 infection.
10/13/20
Huang S, Wang S, Li G, et al. | Medicine
10/13/20
Liu Y, Xie H, Gao H, et al. | Medicine
10/13/20
Tasnim S, Rahman M, Pawar P, et al. | medRxiv
Aim: To assess the current evidence on the epidemiological burden, associated factors, and interventions from the existing literature. 
10/13/20
Yu CC, Hlaing T | PROSPERO
10/13/20
Raya BA, Mijovic H, Donken R, et al.  | Research Square
Aim: To review the outcomes of patients with COVID-19 treated with different pharmacological treatments in randomized controlled trials (RCTs).
10/13/20
Liu Z, Zhang Y | PROSPERO
10/13/20
Vindrola-Padros C, Singh K, Sidhu MS, et al. | medRxiv
Aim: To analyse the implementation and impact of remote home monitoring models (virtual wards) during COVID-19, identifying their main components, processes of implementation, target patient populations, impact on outcomes, costs and lessons learnt.
UPDATED
10/13/20
Lugli G, Ottaviani MM, Botta A, et al. | medRxiv
Aim: To investigate the management of non-COVID-19 patients across all medical specialties during the pandemic in Italy. 
10/13/20
Pranata R, Lim M, Yonas L, et al.  | PROSPERO
10/13/20
Yao J, Shao G, Cui Y, et al.  | PROSPERO
10/12/20
Schunke L, Andre da Costa C, Antunes RS, et al.  | PROSPERO
10/12/20
de Jesus Dantas Ferreira L, dos Santos Goncalves M, dos Santos Cordeiro G, et al.  | PROSPERO
10/12/20
Barboza J, Chambergo-Michilot D, Velasquez-Sotomayor M, et al.  | PROSPERO
10/12/20
Barboza J, Chambergo-Michilot D, Velasquez-Sotomayor M, et al.  | PROSPERO
10/12/20
Sarma P, Bhattacharyya A, Kaur H, et al.  | PROSPERO
10/12/20
Sarma P, Bhattacharyya A, Kaur H, et al.  | PROSPERO
10/12/20
Sanots G, Silva H, Leite A, et al.  | PROSPERO
10/12/20
Walsh S, Mytton B, Braithwaite V, et al.  | PROSPERO
10/12/20
Sun C, Chen Y, Hu L, et al.  | PROSPERO
10/12/20
Sahu AK, Sahu AK | PROSPERO
10/12/20
Jiaming F, Yingying M, Liang Q | PROSPERO
10/12/20
Hung KC, Sun CK, Chen IW, et al. | PROSPERO
10/12/20
Turner C, Natolanda P | PROSPERO
10/9/20
Fitzpatrick-Lewis D | McMaster University
10/9/20
Griswold D, Gempeler A, Kolias A, et al  | medRxiv
Aim: To identify and summarize the available literature regarding the efficacy of different personal protective equipment (PPE) for reducing the risk of COVID-19 infection in health personnel caring for patients undergoing trauma surgery in low-resource environments (LREs).
10/9/20
Kaushal K, Kaur M, Kumar S, et al.  | PROSPERO
10/9/20
Wakhloo T, Chug A, Dixit A, et al . | PROSPERO
10/9/20
Yu Z, Li D, Zhao X, et al.  | PROSPERO
10/8/20
Talarico F, Chakravarty S, Liu Y, et al. | medRxiv
Aim: To review the evidence on the psychiatric side effects associated with chloroquine and hydroxychloroquine.
10/8/20
Guo XG, Cao XJ, Fang KY, et al.  | PROSPERO
10/7/20
Boychuck Z, Ogourtsova T, Znaty A, et al | PROSPERO
10/7/20
Low JM, Amin Z, Peng Mei YNG | PROSPERO
10/7/20
Saadatjoo S, Miri M, Hassanipour S, et al. | medRxiv
Aim: To investigate and synthesize the current evidence on KAPs regarding COVID-19.
UPDATED
10/7/20
Chen Y, Zhu C, Xu Z, et al. | Medicine
10/7/20
Ravindra K, Malik VS, Padhi BK, et al. | medRxiv
Aim: To investigate the role of asymptomatic infection worldwide reported in family-cluster, adults, children, health care workers, and travelers. 
10/7/20
Qiu X, Nergiz AI, Maraolo AE, et al. | medRxiv
Aim: To critically appraise available data about secondary attack rates from people with asymptomatic and pre-symptomatic SARS-CoV-2 infection.
10/7/20
Penna P, Oliveira N, Hermsdorff H | PROSPERO
10/7/20
Anathan VA, Veerakumar AM, Ram Prabhakar V.  | PROSPERO
10/7/20
Costanzo S, Parisi R, Di Castenuovo A, et al  | PROSPERO
10/7/20
Meseret M, Regasa Z, Hailiye G, et al  | PROSPERO
10/7/20
Heath L, Carey M, Lowney A, et al  | PROSPERO
10/7/20
Zhang Y, Yu S, Xu Y, et al. | medRxiv
Aim: To explore the impact of RAS inhibitor use on the risk of SARS-CoV-2 infection and the prognosis of SARS-CoV-2 infected patients, from all published studies. 
10/7/20
Sah SK, Undela K, Chand S, et al.  | medRxiv
Aim: To review the evidence on the safety and efficacy of essential pharmacotherapy during the pharmacological management of COVID-19. 
UPDATED
10/7/20
Diogo P, Lemos e Sousa O, Rodrigues J, et al  | PROSPERO
10/7/20
Wang X, Wang X, Chen JX | PROSPERO
10/6/20
Zhang Z, Ai G, Chen L, et al. | Research Square
Aim: To explore the association of immunological features with COVID-19 severity.
10/6/20
Desai M, Deshpande G, Elenwa F, et al | PROSPERO
10/6/20
Chen J, Gong L, Gong Q, et al | PROSPERO
10/6/20
Silveira LC, da Silva Santos R, da Silva Reis AA | PROSPERO
10/6/20
Ahmad A | Central Council for Research in Ayurvedic Sciences
10/6/20
Ahmad A | Central Council for Research in Ayurvedic Sciences
10/6/20
Xu J | PROSPERO
10/6/20
Saragih ID, Saragih IS, Lin CJ | PROSPERO
10/6/20
Flores GMY, Ramos GT, Cantoral JEH, et al  | PROSPERO
10/6/20
Dobbins M | National Collaborating Centre for Methods and Tools
10/6/20
Hammound A, Khalid T, Thornton H, et al | PROSPERO
10/6/20
Rutkowski S, Czech O, Wrzeciona A, et al  | PROSPERO
10/6/20
Sakuraba A | PROSPERO
10/6/20
Liu J, Yin X, Liao J, et al  | PROSPERO
10/6/20
Rutkowski S, Czech O, Wrzeciono A, et al  | PROSPERO
10/5/20
Taylor E, Macleod K, Scribante J, et al  | PROSPERO
10/5/20
Garcia-Albeniz X, Del Amo J, Polo R, et al. | medRxiv
Aim: To review the evidence on the effectiveness of HCQ to prevent COVID-19.
10/5/20
Kim S, Shin Jae II, Lee KH | PROSPERO
10/5/20
Morales NG, Cotrina SA, Miranda JMA, et al  | PROSPERO
10/5/20
Morales NG, Cotrina SA, Miranda JMA, et al  | PROSPERO
10/5/20
Hernandez MCV, Suarez JAR, Munos CAB, et al  | PROSPERO
10/5/20
Tadesse DB, Gebrewahd GT, Gerensea H | PROSPERO
10/5/20
Mao W, Vos T, Hanson SW, et al  | PROSPERO
10/5/20
Zorrilla E, Ottur M, Luu K, et al  | PROSPERO
10/5/20
Lee J, Chi G | PROSPERO
10/5/20
Guo XG, Li XJ, Cao XJ, et al  | PROSPERO
10/5/20
Cui Y, Yao J, Shao G, et al  | PROSPERO
10/2/20
Neal E, Russell F, Curtis N, et al  | PROSPERO
10/2/20
Siahaan YMT, Puspitasari V, Pangestu AR | Research Square
Aim: To determine the clinical profile, laboratory, and imaging results of encephalitis associated with COVID-19.
10/2/20
Beiter K, Lau FH, Danos D | Research Square
Aim: To evaluate VDD and COVID-19 mortality worldwide during the first 50 days of the pandemic as experienced by each country.
10/2/20
Rahman MM, Bhattacharjee B, Farhana Z, et al. | medRxiv
Aim: To chronicle the prevalence and correlations of symptoms and comorbidities, and associated covariates among the patients.
10/1/20
Doumouchtsis S | PROSPERO
10/1/20
Gebrewahd G, Tadesse D, Gebreamlak G, et al  | PROSPERO
10/1/20
Sethia R, Prasad M, Jagannath S | medRxiv
Aim: To review the evidence on the use of famotidine in COVID-19.
10/1/20
Ahammed T, Anjum A, Rahman MM, et al. | medRxiv
Aim: To estimate the R0 and CFR of COVID-19 and assess whether the parameters vary in different regions of the world.
UPDATED
10/1/20
Morales Gomez CBM, Sagredo K, Saavedra JA | PROSPERO
10/1/20
Ladapo JA, McKinnon JE, McCullough PA, et al. | medRxiv
Aim: To determine if hydroxychloroquine (HCQ) reduces the incidence of new illness, hospitalization or death among outpatients at risk for or infected with SARS-CoV-2 (COVID-19).
10/1/20
Luna E, Figueiredo G, Campos S | PROSPERO
10/1/20
Dowsett L, Mastikhina L, Egunsola O, et al  | PROSPERO
9/30/20
Galindo L, de Olivera Neto OB, Pinheiro IL, et al  | PROSPERO
9/30/20
Gundeti MS, Ahmad A, Rai AK, et al  | PROSPERO
9/30/20
Poole-Wright K, Gaughran F, Chalder T | PROSPERO
9/30/20
Liampas A, Zis P | PROSPERO
9/30/20
Goncalves AK, Medeiros K, Sarmento AC, et al  | PROSPERO
9/30/20
Riches S, Azevedo L, Valmaggia L | PROSPERO
9/29/20
Hassanipour S, Faradonbeh SB, Momeni K, et al. | medRxiv
Aim: To investigate the clinical manifestation include signs and symptoms, laboratory results, and perinatal outcomes in pregnant women with COVID-19.
9/29/20
Fan H, Wang L | PROSPERO
9/29/20
Munro A, Gray M, Mohan A, et al | PROSPERO
9/29/20
Sarkar S, Khanna P, Sing A | PROSPERO
9/29/20
de Souza TA, de Almeida Medeiros A, da Silva Nunes AD, et al  | PROSPERO
9/29/20
Thompson W, Teoh L | PROSPERO
9/29/20
Rahimi M, Ghaffari S, Daneshvar S | PROSPERO
9/29/20
Verdugo-Paiva F, Acuna MP, Sola I, et al. | medRxiv
Aim: To provide a timely, rigorous and continuously updated summary of the evidence available on the role of remdesivir in the treatment of patients with COVID-19.
9/29/20
Tian L, Shao X | PROSPERO
9/29/20
JunJian M,, KeFan W, PeiXin J | PROSPERO
9/29/20
Yan Y, Mao J, Gao X, et al  | PROSPERO
9/29/20
Wang YY, Xiang Yu-Tao, Jin Yu, et al  | PROSPERO
9/28/20
Rubio-Rivas M, Mora-Lujan JM, Montero A, et al. | medRxiv
Aim: To summarize evidence about the effect of TCZ to treat severe COVID-19.
9/28/20
Wungu C, Khaerunnisa S, Putri E, et al. | PROSPERO
9/28/20
Hashan MR, Smoll N, King C, et al. | PROSPERO
9/28/20
Lazarus G, Audrey J, Wangsaputra V, et al  | medRxiv
Aim: To investigate the prognostic value of admission blood glucose (BG) in predicting COVID-19 outcomes, including poor composite outcomes (mortality/severity), mortality, and severity. 
UPDATED
9/28/20
Saragih ID, Suarilah I | PROSPERO
9/28/20
Leons-Rojas J, Restrepo-Rodas G, Mancero R, et al. | PROSPERO
9/28/20
Griswold D, Gempeler A, Kolias A, et al  | medRxiv
Aim: To summarise the effects of different personal protective equipment (PPE) for reducing the risk of COVID-19 infection in health personnel caring for patients undergoing trauma surgery.
UPDATED
9/28/20
Adjei G, Thomford N, Enuameh Y | PROSPERO
9/28/20
Kharoud HK, Asim R, Siegel L, et al. | medRxiv
Aim: To conduct a systematic review and meta-analysis to assess the prevalence of various clinical symptoms and laboratory findings of COVID-19 in children.
UPDATED
CLINICAL CHARACTERISTICS
9/28/20
Espinoza SKF, Vasquez MT, Miranda JMA | PROSPERO
9/28/20
Hung D, Aziz JA, Ghula S, et al.  | PROSPERO
9/28/20
Concha GMP, Gutierrez JBO, Flores AAR | PROSPERO
9/28/20
Neil-Sztramko S, Dobbins M | PROSPERO
9/25/20
Dowsett L, Egunsola O, Mastikhina L, et al. | PROSPERO
9/25/20
Dowsett L, Clement F, Farkas B, et al. | PROSPERO
9/25/20
Fang C, Zhou Z, Zhou M, et al. | Research Square
Aim: To examine the relationship between BMI and severity and mortality of patients with coronavirus disease 2019 (COVID-19).
9/25/20
Moulin M, Ali S, John-Baptiste A | PROSPERO
9/25/20
Maheu-Cardotte MA, Lapierre A, Fontaine G, et al. | PROSPERO
9/25/20
Maitra S, Behera S, Gouri M, et al.  | PROSPERO
9/25/20
Naveed S, Akhtar P, Meraj H, et al. | PROSPERO
9/25/20
Yadav A, Ghosh S, Dubey S | PROSPERO
9/25/20
Currie C, Larouche R, Voss L , et al | Syst Rev
UPDATED
9/25/20
Brotis A, Karvouniaris M, Poulakou G | PROSPERO
9/25/20
Pranata R, July J | PROSPERO
9/25/20
Michelen M, Sigfrid L, Manoharan L, et al.  | PROSPERO
9/24/20
Variava T, Watermeyer | PROSPERO
9/24/20
Ali R, Farah E, El-Zein M, et al  | PROSPERO
9/24/20
Wang Y, Li W, Jiang Z, et al. | Medicine
9/24/20
Malik A, McFadden S, Pischel L, et al  | PROSPERO
9/24/20
Wolf S, Zeibig J, Seiffer B, et al. | Research Square
Aim: To provide a systematic overview of the literature with regard to associations between physical activity (PA) and depression and anxiety during the COVID-19 pandemic. 
9/24/20
Pegorari MS, Matos AP, Iosimuta NCR, et al. | Rev Assoc Med Bras
9/24/20
Zhang Y, Ren T, Li H, et al  | Medicine
9/24/20
Gebremeskel G, Haile T | PROSPERO
9/24/20
Qian W, Ye Y, Zuo L, et al. | Research Square
Aim: To assess the safety of ICI application in COVID-19 patients and to make reasonable recommendations by reviewing available publications.
9/24/20
Zawai AT, Alwafi H, Naser AY, et al  | PROSPERO
9/24/20
Guadie H, Zeleke A, Desta C, et al  | PROSPERO
9/24/20
Peter HJ, Vancsa S, Kiss S, et al  | PROSPERO
9/24/20
Xiong X, Chi J, Gao Q | Research Square
Aim: To determine the prevalence and risk factors of thrombotic events on COVID-19 patients.
9/24/20
Du L, Chen Y, Li Y, et al. | Medicine
9/24/20
Liu M, Zhu H, He Y, et al. | Medicine
9/24/20
Mellor M, Bast A, Jones N, et al. | medRxiv
Aim: To assess whether people living with HIV (PLWH) are at increased risk of COVID-19 mortality or adverse outcomes, and whether antiretroviral therapy (ART) influences this risk. 
9/24/20
Dar JA, Amber S, Mujaddadi A | PROSPERO
9/24/20
Peng J, Wu Z, Zhong H, et al. | Medicine
9/24/20
Zhangmeng X, Yong C, Yu D, et al  | Medicine
9/24/20
Zhang J, Li S, Zhao C, et al. | Medicine
9/23/20
Davids J, Monrouxe L, Hockey P, et al  | PROSPERO
9/23/20
Tierney S, Wong G, Turk A, et al | PROSPERO
9/23/20
Gagliardi R, Pires G | PROSPERO
9/23/20
Wang X, Ma S  | PROSPERO
9/23/20
Tolsa MD, Malas O | PROSPERO
9/23/20
Vasquez MT, Espinoza SKF, Miranda JMA, et al  | PROSPERO
9/21/20
Wang B, Andraweera P, Elliot S, et al.  | PROSPERO
9/21/20
Civi RM, Azhir A, Landi A | PROSPERO
9/21/20
Rubio L, de las Heras SM | PROSPERO
9/21/20
Zhang X, Liao X | PROSPERO
9/21/20
Bazargani MHM, Rastad H, Shafiabadi N | PROSPERO
9/21/20
Mohanty R, Meher BR, Padhy BM, et al.  | PROSPERO
9/21/20
Xie B, Yang Z, Liu C, et al.  | PROSPERO
9/21/20
Lee KW, Yap SF, Ngeow YF, et al.  | PROSPERO
9/21/20
Butt M, Shirke S, Makkar S, et al.  | PROSPERO
9/21/20
Butt M, Shirke S, Makkar S, et al.  | PROSPERO
9/21/20
Shekar R, Sheikh AB, Sagheer S, et al.  | PROSPERO
9/21/20
Sarah ID, Ice SS, Batubara SO, et al.  | PROSPERO
9/21/20
Baral R, Vssiliou V | PROSPERO
9/21/20
Wang Q, Wang T, Wang Y, et al.  | PROSPERO
9/21/20
Yan H, Ding Y, Guo W | PROSPERO
9/21/20
Ramonfaur D, Gonzalez CA, Paredes-Vazquez JG | medRxiv
Aim: To summarize all the proposed mechanisms by which PTX may aid in the treatment of COVID-19, as well as prevent its deadly complications. 
9/21/20
Ferreira-Souza LF, Torres-Nunes L, Moura-Fernandes MC, et al.  | PROSPERO
9/21/20
Ojimbo KO, Kisangala E, Namisango E, et al.  | PROSPERO
9/21/20
Sadjadi M, Moerschel KS, Petticrew M | medRxiv
Aim: To systematically review qualitative literature on social distancing in order to identify and describe factors that enable or prevent its implementation. 
9/21/20
Maria van Bohemen AEC, Skarp J, Hauck K | PROSPERO
9/21/20
Wang Y, Chen X, Luo G, et al.  | PROSPERO
9/21/20
Zhan ZQ, Guo XG, Cai GN | PROSPERO
9/21/20
Kim E, Jeong A | PROSPERO
9/21/20
Du M, Zhao J, Yin X, et al. | medRxiv
Aim: To analyze the risk factors (vital signs) that affect the prognosis of COVID-19 patients.
9/21/20
Wildwing T, Holt N, et al. | medRxiv
Aim: To provide health professionals with better accessibility to available evidence, this paper summarises findings from a systematic overview of systematic reviews of the neurological symptoms seen in patients with COVID-19.
UPDATED
9/21/20
Lu H, Chen C, Wu Y | PROSPERO
9/21/20
Kadharusman MM, Sutanto RL, Tjoa K, et al.  | PROSPERO
9/21/20
Levi J, Hill A, Heath K, et al.  | PROSPERO
9/21/20
Wu X, Li W, Qi Z, et al. | PROSPERO
9/21/20
Edwards T, Santos VS, Wilson AL, et al. | medRxiv
Aim: To describe whether SARS-CoV-2 viral loads (VLs) and cycle thresholds (CTs) vary by sample type, disease severity and symptoms duration. 
UPDATED
9/18/20
Abeldano RA, Coca SM, Abeldano GF, et al. | Research Square
Aim: To assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection.
9/18/20
De Guzman K, Snoswell CL, Smith AC | PROSPERO
9/18/20
Benzouak T, Rao S, Kisely S, et al.  | PROSPERO
9/18/20
Dobbins M | National Collaborating Centre for Methods and Tools
9/18/20
Walle IV, Leitmeyer K, Broberg EK | medRxiv
Aim: To review the clinical performance of SARS-CoV-2 nucleic acid, viral antigen and antibody tests
9/18/20
Axfors C, Schmitt AM, Janiaud P et al. | medRxiv
Aim: To estimate the effects of hydroxychloroquine and chloroquine on 4 survival in COVID-19 from all currently available RCT evidence, published and unpublished
9/18/20
Corona G, Pivonello R, Isidori A, et al.  | PROSPERO
9/18/20
Chess K, Jacobson TA, Smith LE, et al. | Research Square
Aim: To synthesize literature on SARS-CoV-2 seroprevalence studies, including sampling frames, study characteristics, assay test performance characteristics, and proportion of participants with IgG and IgM SARS-CoV-2 antibodies.
9/17/20
Lo K, Liu S | PROSPERO
9/17/20
Ang Y, Soo R, Soon YY | PROSPERO
9/17/20
Agarwal A, Basmaji J, Faisal H, et al.  | PROSPERO
9/17/20
Alcock H, Moppett E, Moppett I | PROSPERO
9/17/20
Abdallah I, Aabdien M | PROSPERO
9/17/20
Meena J, Jain S, Kumar j, et al.  | PROSPERO
9/17/20
van Zuylen M, Bribnau A, Admiraal M, et al.  | PROSPERO
9/17/20
Chen Y, Zuo YY, Zheng H, et al.  | PROSPERO
9/15/20
Elsayed HH, Hassaballa AS, Ahmed TA, et al. | Research Square
Aim: To review the evidence on the use of ECMO for COVID-associated ARDS to study its outcomes.
UPDATED
9/15/20
Simadibrata DM, Calvin J, Wijaya AD, et al. | medRxiv
Aim: To investigate whether NLR levels on admission could predict the severity and mortality of COVID-19 patients.
9/15/20
Botelho MS, Bolfi F, Leite RGOF, et al. | Research Square
Aim: To evaluate the safety of CQ and HCQ from malarial and non-malarial randomized clinical trials (RCTs).
UPDATED
9/14/20
Zuniga RAA, Coca S, Abeldano G, et al. | medRxiv
Aim: To assess the clinical effectiveness of drugs used in hospitalized patients with COVID-19 infection. 
9/14/20
Abbas KS, Luu M, Elghezewi ASK, et al. | Research Square
Aim: To review the current decontamination methods to reuse masks and respirators.
9/14/20
Ji HJ, Su Z, Zhao R, et al. | medRxiv
Aim: To investigate whether abnormal fibrinolysis is a culprit or protector or both in the clinical progression of COVID-19.
9/14/20
Kaur U, Chakrabarti SS, Patel TK | medRxiv
Aim: To provide a pooled estimate of the effect of RAAS blocker usage on COVID-19 outcomes. 
9/14/20
Cirillo N | medRxiv
Aim: To facilitate a timely understanding of the differences in the prevalence of gustatory disturbances (GD) in individuals infected with SARS-CoV-2.
9/11/20
Maguire BJ, Guerin PJ | Wellcome Open Res
9/11/20
De Lorenzo A, Kasal D, Tura B, et al. | medRxiv
Aim: To review the evidence on cardiac complications of COVID-19.
9/11/20
Yan H, Ouyang Y, Wang L, et al. | Medicine
9/11/20
Liu Y, Fu X, Xie C | Medicine
9/11/20
Gnanvi JE, Salako VK, Kotanmi B, et al. | medRxiv
Aim: To conduct a global systematic literature review to summarize trends in the modelling techniques used for Covid-19
9/11/20
Gao W, li J, Huang G | Medicine
9/11/20
Torres AZ, Lopez-Leon S, Muthuvel T, et al. | medRxiv
Aim: To systematically review the safety and efficacy outcomes of using antivirals for the treatment of COVID-19.
UPDATED
9/10/20
Carreno Hernandez FL, Cardena Bolivar YR | PROSPERO
9/10/20
Bahji A, Crickford D | PROSPERO
9/10/20
Li Y, Weng Q, Huang X, et al. | Medicine
9/10/20
Singh A, Keri V | PROSPERO
9/10/20
Christensen H, Turner K, Trickey A, et al. | medRxiv
Aim: To provide a rapid review and appraisal of the literature on mathematical models investigating COVID?19 infection in a university setting.
9/10/20
Kula B, Schwartz I | PROSPERO
9/10/20
Meena J, Singh M, Jaiswal N, et al.  | PROSPERO
9/10/20
Shekhar R, Sheikh AB, Upadhyay S, et al.  | PROSPERO
9/10/20
Staibano P, Sommer D, McHugh T | PROSPERO
9/10/20
Divatia J, Nadkarni A, Vijayakumaran SC | PROSPERO
9/10/20
Jones M, Cashin A, Arnold R, et al.  | PROSPERO
9/10/20
Wang Y, Ma , Li Y, et al.  | PROSPERO
9/10/20
Zhang Y, Xie H, Li Y, et al. | Medicine
9/10/20
Yu Z, Wang P, Chen B, et al.  | PROSPERO
9/10/20
Bendezu Quispe GJP, Hernandez Vasquez AA, Comande D | PROSPERO
9/10/20
da Silva Junior SV, de Godoi Caceres NT, Lordao AV, et al.  | PROSPERO
9/10/20
Shekar R, Sheukh AB, Upadhyay S, et al.  | PROSPERO
9/10/20
Ma J, Tang L, Feng Y | PROSPERO
9/10/20
Wilson L, Michtalik H, Robinson K | PROSPERO
9/10/20
Hailay A, Aberhe W, Zereabruk K, et al  | Asthma Res Pract
9/10/20
Elshafei M, Khalil A, El-Bardissy A, et al. | Medicine
9/10/20
Huang T, Song D, Wei Y, et al.  | PROSPERO
9/10/20
Liu Y, Yang Y, Chen Y, et al. | Medicine
9/9/20
Cairoli FR, Mazzoni A, Berrueta M, et al.  | PROSPERO
9/9/20
Chen C, Lu H, Wi Y | PROSPERO
9/9/20
Amani B, Khanijahani A, Amani B | PROSPERO
9/9/20
Hoang T | medRxiv
Aim: To examine the characteristics of repositive COVID-19 cases.
9/9/20
Mu R, Yi Z, Xu C, et al.  | PROSPERO
9/9/20
Wu Y, Li H, Li S  | Research Square
Aim: To summarize current evidence regarding the risk of death and the severity of COVID-19 as well as risk factors for severe COVID-19.
9/9/20
AbdelMassih A, Fouda R, Essam R, et al. | Research Square
Aim: To use the relevant case reports and series to determine the percentage of newborns who test positive in COVID-19 positive mothers.
9/9/20
Angulo-Bazan Y, Solis G, Acosta J, et al. | medRxiv
Aim: To describe the characteristics of SARS-CoV-2 infection among household members with a confirmed primary case of COVID-19 in low burden districts in Metropolitan Lima. 
9/9/20
Peng A, Wang X | PROSPERO
9/9/20
Joo JY, Liu M | PROSPERO
9/9/20
Iloanusi S, Mgbere O, Essein E | PROSPERO
9/9/20
Goettens M, Cademartori M, Azevedo M, et al.  | PROSPERO
9/9/20
Jayaraj R | PROSPERO
9/9/20
Marziale MHP, Cassenote AJF, Fracarolli IFL, et al. | PROSPERO
9/9/20
Anikpezie N, Ngujede A, Osaghae I, et al.  | PROSPERO
9/9/20
Amani B, Amani B, Khanijahani A | PROSPERO
9/9/20
Puppo H, Torres-Castro R, Vasconcello-Castillo L, et al. | PROSPERO
9/8/20
Pamplona EA, de Oliveira RAF, da Silva Ferreira BNM | PROSPERO
9/8/20
Meena JP, Gupta AK, Pandey RM | PROSPERO
9/8/20
Beressa TB, Sahilu T, Deyno S | medRxiv
Aim: To systematically review and summarize the influence of Renin-Angiotensin-Aldosterone System (RAAS) inhibitors on the outcome of COVID_19 patients with hypertension.
9/8/20
Serrano-Ripoll M, Ricci-Cabello I, Zamanillo-Campos R, et al. | PROSPERO
9/8/20
Getnet B, Degu A, Yenealem F, et al.  | PROSPERO
9/8/20
Sarfraz A, Sarfraz Z, Sanchez-Gonalez MA, et al. | medRxiv
Aim: To investigate whether remdesivir is effective for treating COVID-19 including reduced in-hospital adverse events, oxygen support, and mortality rates.
9/8/20
Cui L, Cheng W, Li Y, et al.  | PROSPERO
9/8/20
Liu Q, Mabilisa S, Mujuru K | PROSPERO
9/8/20
Giuffre M, Palmucci S | PROSPERO
9/8/20
Zhu X, Luo Z, Cheng X, et al.  | PROSPERO
9/8/20
Zhu X, Chi W, Luo Z, et al.  | PROSPERO
9/8/20
Kurt M, Abasiyanik Z, Kahraman T | PROSPERO
9/8/20
Segawa I, Ouma KO, Nate RW, et al.  | PROSPERO
9/7/20
Palsuledesai S, Wagle S, Thakur H, et al  | PROSPERO
9/7/20
Widding-Havneraas T, Chaulagain A, Lyhmann I, et al  | PROSPERO
9/7/20
Majid A | PROSPERO
9/7/20
Monroy CG, Martinez EM, Sanchez CMO, et al  | PROSPERO
9/7/20
Tristao LS, Bernardo WM | PROSPERO
9/7/20
Khan S, Mishra P, Parveen R, et al  | PROSPERO
9/7/20
Campbell F, Blank L, Cantrell A, et al  | PROSPERO
9/7/20
Brainard J, Pond K, Hooper L, et al  | PROSPERO
9/4/20
Wang J, Mo Y, Su Y, et al. | medRxiv
Aim: To systematically analyze the chest CT imaging features of children with COVID-19 and provide references for clinical practice. 
9/4/20
Sarkar S, Khanna P, Singh A | PROSPERO
9/3/20
Liu N, Zhang T, Ma L, et al. | Medicine
9/3/20
Zhou M, Liang Q, Pei Q, et al. | Medicine
CANDIDATE THERAPEUTICS
9/3/20
Wen D, Shi Y, Zhang X, et al. | Medicine
9/3/20
Xingxianf R, Xiankun W | PROSPERO
9/3/20
Zheng P, Bao L, Yang W, et al. | Medicine
CLINICAL CHARACTERISTICS
9/3/20
Chen C, Weng Q, Li Y, et al. | Medicine
9/3/20
Rattka M, Imhof A, Baymhardt M, et al  | PROSPERO
9/3/20
Ananthan Vam Bhat A, Reddy MM, et al  | PROSPERO
9/3/20
Yang Y, Liu X, Liu Y, et al. | Medicine
CANDIDATE THERAPEUTICS
9/3/20
Ching LY, Qiao F, Weihan L, et al  | PROSPERO
9/3/20
Liu N, Zhang T, Ma L, et al. | Medicine
9/3/20
Tian H, Xue Y, Yao RR, et al | Medicine
9/3/20
Zhou K, Dong S, Wang K, et al. | Medicine
9/3/20
Indraccolo U | PROSPERO
9/3/20
Luo W, Nie Y, Tan Y, et al  | PROSPERO
9/3/20
Golinelli D, Boetto E, Maietti E, et al. | medRxiv
Aim: To investigate the association between SARS-CoV-2 infection and ABO blood group polymorphism, and determine SARS-CoV-2 positive individuals odds of having a specific blood group compared to controls.
9/3/20
Rooney A, Badenoch J, Watson C, et al  | PROSPERO
9/3/20
Mohanty R, Meher BR, Biswamohan P, et al  | PROSPERO
9/3/20
Huang J, Wu L, Ren X, et al. | Medicine
9/2/20
Innes N, Johnson I, Al-Yaseen W, et al. | medRxiv
Aim: To identify which clinical dental procedures do generate droplets and aerosols with subsequent contamination, and for these, characterise their pattern, spread and settle.
9/2/20
Parohan M, Yaghoubi S, Djalali M, et al. | medRxiv
Aim: To summarize available studies on the association between acute kidney injury and severity of COVID-19 infection. 
9/2/20
Mariadas R, Jayakody S | PROSPERO
9/2/20
Karam M, Althuwaikh S, Alazemi M, et al. | medRxiv
Aim: To compare the performance of chest computed tomography (CT) scan versus reverse transcription polymerase chain reaction (RT-PCR) in the initial diagnostic assessment of coronavirus disease 2019 (COVID-19) patients. 
9/2/20
Lau V, Rewa O, Sebastianski M, et al  | PROSPERO
9/2/20
Jacques TL, Nyasulu P, Birhanu A | PROSPERO
9/2/20
Maitra S, Baidya DK, Bhattacharjee S, et al. | medRxiv
Aim: To know worldwide prevalence of thromboembolic events in COVID-19 patients.
9/2/20
Su Z, Wagers S, Lopez E, et al. | Research Square
9/2/20
Rostami A, Sepidarkish M, Leeflang M, et al. | medRxiv
Aim: To estimate the global and regional anti-SARS-CoV-2 seroprevalence rates in humans and assess whether seroprevalence associates with geographical, climatic and socio-demographic factors. 
9/2/20
Tomfohr-Madsen L, Racine N, Lebel C, et al  | PROSPERO
9/2/20
Sarkar S, Khanna P, Singh A | PROSPERO
9/2/20
Wingert A, Pillay J, Gates M, et al. | medRxiv
Aim: To determine the magnitude of association between potential risk factors and risk of severe outcomes of COVID-19.
UPDATED
9/2/20
Hseih E, Conway R, Konig M, et al  | PROSPERO
9/2/20
Parkinson N, Rodgers N, Fourman MH, et al. | medRxiv
Aim: To identify host factors involved in human betacoronavirus infection (SARS-CoV-2, SARS-CoV, MERS-CoV, seasonal coronaviruses).
9/2/20
Kenmoe S, Kengene-Nde C, Ebogo-Belobo JT, et al. | medRxiv
Aim: To clarify the prevalence of respiratory viruses in children with bronchiolitis in the coronavirus disease 2019 pandemic context. 
9/2/20
Su Z, McDonnell D, Liang B, et al. | Research Square
9/2/20
Kataoka Y, Oide S, Ariie T, et al. | medRxiv
Aim: To investigate the methodological quality of COVID-19 systematic reviews (SRs) indexed in medRxiv and PubMed, compared with Cochrane COVID Reviews.
9/1/20
Galbadage T, Jalali AM, Khoury SG, et al  | PROSPERO
9/1/20
Borstein S | Newfoundland and Laborador Centre for Applied Health Research
9/1/20
Maghrabi K, Alsamman A, Patel S | PROSPERO
9/1/20
Nieuwlaat R | PROSPERO
9/1/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
9/1/20
Tripura K, Karmakar N, Datta A, et al  | PROSPERO
9/1/20
Kovoor J, Tivey D, Ovenden C, et al  | PROSPERO
9/1/20
Coclite D, Napoletano A, Gianola S, et al | medRxiv
Aim: To review the evidence on the effectiveness of wearing face masks in the community to prevent SARS-CoV-2 transmission.
9/1/20
Saleh AS, Roshdy A, Elsayed AS, et al  | PROSPERO
9/1/20
Thomas PE, Javeth A | PROSPERO
9/1/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
9/1/20
Zhou X, Cheng Z, Hu Y | PROSPERO
9/1/20
Hughes S, Canfell K, Carle C, et al  | PROSPERO
9/1/20
Habteyes T, Gamtesa D, Gutema G | PROSPERO
9/1/20
Santos MO, Avelino M, Carneiro LC, et al  | PROSPERO
9/1/20
Saliva PCR for the diagnosis of SARS-CoV-2: a systematic review and meta-analysis | PROSPERO
9/1/20
Tadesse B, Getahun H, Alemu Y | PROSPERO
9/1/20
Vuncannon J, Adler J, Bennett S, et al  | PROSPERO
9/1/20
Bornstein S | Newfoundland and Laborador Centre for Applied Health Research
8/31/20
Post N, Eddy D, Huntley C, et al. | medRxiv
Aim: To comprehensively evaluate the evidence describing the antibody response to SARS-CoV-2.
8/31/20
Shrotri M, van Schalkwyk MCI, Post N, et al. | medRxiv
Aim: To summarize current understanding of the cellular response to SARSCoV-2 infection, specifically exploring the role that T cell-mediated immunity might play in resistance to severe infection, clinical and virological recovery, and long-term protection.
8/31/20
Lopes-Junior L, Bomfim E, da Silveira DSC, et al. | BMJ Open
8/31/20
Baxter S, Barnes A, Lee C, et al. | Research Square
Aim: To examine evidence on initiatives to increase peoples’ involvement in local decision-making, with a focus on how this may be affected by resource constraints.
8/31/20
Mohamed MFH, A-Shokri S, Yousaf Z, et al. | medRxiv
Aim: To systematically review the literature and explore the pooled prevalence of VTE, PE, and DVT in critically ill COVID-19 patients.
8/31/20
Jackson L, Danila M, Owensby J, et al  | PROSPERO
8/31/20
Liu M, Zhu H, Xiong Q, et al  | Medicine
8/31/20
Chung M, Beauchesne AR, Cahoon DS, et al | PROSPERO
8/29/20
Tesfa D, Abebaw S, Digssie A, et al  | PROSPERO
8/28/20
Seidu S, Kunutsor SK, Khunti K, et al  | PROSPERO
8/28/20
Agarwak L, Agarwal A | PROSPERO
8/28/20
Kim MS, An MH | PROSPERO
8/28/20
Karimzadeh S, Elsaid M, Khanh NSL, et al  | PROSPERO
8/28/20
O'Leary T, Iqbal J | PROSPERO
8/28/20
Schulze A, Brand F, Berger N, et al  | PROSPERO
8/28/20
Baker M, Lee L, Hill T, et al  | PROSPERO
8/28/20
Ji B, Xu J | PROSPERO
8/28/20
Ahmad A, Rai AK, Negandhi H, et al  | PROSPERO
8/28/20
Wang J, Zhu X, Sun Y, et al. | Medicine
8/28/20
Tan BBJ, Devi MK | PROSPERO
8/28/20
Torres MAR, Balbin PV, Torres MMR, et al  | PROSPERO
8/28/20
Sarkar S, Khanna P, Singh A | PROSPERO
8/28/20
Vergara-Buenaventura A, Castro-Ruiz C, Chea EC | PROSPERO
8/28/20
Ramirez CR, Silvila CO, Verdugo F | PROSPERO
8/28/20
de Almeida I, Cunha L, Martimbianco AL, et al  | PROSPERO
8/28/20
Chan M, Han Y | PROSPERO
8/28/20
Huang X, Yuan K, Zhang Y, et al  | PROSPERO
8/28/20
Allan S, Clarke T | PROSPERO
8/28/20
Nguyen L, Ryan K | PROSPERO
8/27/20
Walz L, Cohen AJ, Rebaza AP, et al. | Research Square
Aim: To evaluate role of Janus-kinase inhibitors and Type I interferons in COVID-19 patients.
8/26/20
Mendonca K, Jacome A, Silva B, Patino C, et al | PROSPERO
8/26/20
Sterne J, Diaz J, Villar J, et al  | Trials
8/26/20
Bayona HH, Cabaluna IT, Dans L, et al  | PROSPERO
8/26/20
Singh S, Khera D, Chugh A, et al | Research Square
Aim: To evaluate the efficacy and safety of Tocilizumab in comparison to standard therapy in the treatment of COVID-19 in adult patients.
8/26/20
Xie Y, Wang Z, Liao H, et al. | Research Square
Aim: To summarize the epidemiologic traits, clinical spectrum, CT results and laboratory findings of the COVID-19 pandemic.
UPDATED
8/26/20
O'Sullivan L, Killeen RP, Doran P, et al. | HRB Open Research
8/26/20
Batra K, Batra R, Sharma M, et al  | PROSPERO
8/26/20
McGarrigle L, Boulton E, Todd C | Research Square
Aim: To identify and evaluate existing apps and websites to support independent engagement in strength and balance exercises by older people.
8/26/20
Zhou Q, Ye S | PROSPERO
8/26/20
Kizhakekara RN, Uahwatanasakul W, Russell F, et al | PROSPERO
8/26/20
O'Leary T | PROSPERO
8/26/20
Kumar N, Janmohamed K, Nyhan K, et al. | Research Square
8/26/20
Azhir A, Azhir A, Clvi MM, et al  | PROSPERO
8/26/20
Syeda HB, Syed M, Sexton KW, et al. | medRxiv
Aim: To conduct a systematic literature review on the role of ML as a comprehensive and decisive technology to fight the COVID-19 crisis in the arena of epidemiology, diagnosis, and disease progression.
8/26/20
Zheng J, Yan Z, Bi Q, et al  | PROSPERO
8/25/20
Bhamani S, Tabani A, Ahmed S, et al | PROSPERO
8/25/20
Kong X, Qi Y, Huang J, et al  | medRxiv
Aim: To review the evidence on the prevalence of cancer in coronavirus disease 2019 (COVID-19)-infected patients and the severe illness incidence and mortality of COVID-19 patients with cancer.
8/25/20
Abdelrahman Z, Liu Q, Jiang S, et al. | medRxiv
Aim: To estimate the impact of current treatments on the efficacy and safety of COVID-19 by a meta-analysis.
8/25/20
Karsenti N, Elsayed S | PROSPERO
8/25/20
Simadibrata DM, Pandhita BAW, Ananta ME, et al. | medRxiv
Aim: To evaluate the association between PLR levels on admission and the severity of COVID-19 patients. 
8/25/20
Gastine S, Pang J, Boshier FAT, et al. | medRxiv
Aim: To describe viral dynamics and estimate the effects of antivirals used to-date.
8/25/20
Booth G, Williams D, Patel H, et al  | PROSPERO
8/24/20
Liang M, Tan S | PROSPERO
8/24/20
Huang R, Xie L, He J, et al  | PROSPERO
8/24/20
Siegel A, Zuo Y, Moghaddamcharkari | PROSPERO
8/24/20
Liu D, Tian Q, Cao M, et al  | PROSPERO
8/24/20
Orimadegun A, Orimadegun B, Adepoju A | PROSPERO
8/22/20
Vieira LG, Camargo LJS, Schneider G, et al. | medRxiv
Aim: To synthesize the scientific evidence on the repercussions of the COVID-19 pandemic on the mental health of pregnant and puerperal women.
8/22/20
Jefferson T, Spencer EA, Brassey J, et al. | medRxiv
Aim: To review the evidence comparing SARS-CoV-2 culture with reverse transcriptase polymerase chain reaction (rt-PCR).
8/21/20
Farooqi A, Gillies C, Khunti K | PROSPERO
8/21/20
Lagos da Silva R, de Morais Gouveia GP, Cunha SV | PROSPERO
8/21/20
Arantes do Amaral MS, Mendes KDS, Hyppolitp MA | PROSPERO
8/21/20
Su Z, Wagers S | PROSPERO
8/21/20
Makram OM, Elfert M, Kouz B, et al  | PROSPERO
8/21/20
Milanese S, Swaminathan N, Shah P, et al  | PROSPERO
8/21/20
Lago da Silva R, dos Santos Souza AT, da Silva Lopes T | PROSPERO
8/21/20
Jiang F, Li R | PROSPERO
8/20/20
Bhamani S, Sajid I, Makhdoom A, et al  | PROSPERO
8/20/20
Su Z, Bently B, Shi F | PROSPERO
8/20/20
Costa E, Rossi T, Santos M | PROSPERO
8/20/20
Churchill R, Riadi I, Kervin L, et al. | Research Square
8/20/20
Anieto EM, Ogdobo V, Nwadilibe IB, et al  | Research Square
8/20/20
Okullo A, Katairo T, Nalugoda F, et al  | PROSPERO
8/20/20
Wilkinson R, Hines L, Holland A, et al  | PROSPERO
8/20/20
Flodgren G, Bruberg K  | PROSPERO
8/20/20
Sarma P, Bhattacharyya A, Kaur H, et al  | PROSPERO
8/20/20
Huntley B, Chauhan S, Berghella V, et al  | PROSPERO
8/20/20
Lim ZJ, Afroz A, Reddy M, et al  | PROSPERO
8/20/20
Dai M, Li X, Zhang Q | PROSPERO
8/20/20
Chatterji M, Kitamura K, Muenig P, et al  | PROSPERO
8/19/20
Lian R, Gao Y, Zhang R, et al. | Research Square
Aim: To analyze research collaboration, interventions, and outcomes in registered SRs of TCM associated with COVID-19.
8/19/20
Khan DS, Lassi Z, Das J, et al  | PROSPERO
8/19/20
Bancej C | Public Health Agency of Canada
8/19/20
Chang R, Elhusseiny KM, Yeh Y, et al. | medRxiv
Aim: To review the evidence on COVID-19 intensive care unit (ICU) patient characteristics, rates and risks of invasive mechanical ventilation (IMV) and associated outcomes.
8/19/20
Klugar M, Riad A, Klugarova J, et al  | PROSPERO
8/19/20
Roshdy A, Saleh AS, Elsayed AS | PROSPERO
8/19/20
Neil-Sztramko S | National Collaborating Centre for Methods and Tools
8/19/20
Neil-Sztramko S | National Collaborating Centre for Methods and Tools
8/19/20
Khan DS, Lassi Z, Das J, et al  | PROSPERO
8/19/20
Su Z, Meyer K, Li Y, et al. | Research Square
8/19/20
Munhoz I, Lacerda A, Rocha TJM | PROSPERO
8/19/20
Mishra P, Parveen R, Agarwal NB, et al  | PROSPERO
8/18/20
Bhatia R, Gupta S, Bajpai M, et al  | PROSPERO
8/18/20
Kasemi A, Mohammadi V, Aghababaee SK | PROSPERO
8/18/20
Mahendran S, Amarasekera AT, Malaty M, et al  | PROSPERO
8/18/20
Mbakaya B, Chisale M, Sinyiza F, et al  | PROSPERO
8/18/20
Fernando M, Dharmage S, Lodge C | PROSPERO
8/18/20
Yang L | PROSPERO
8/18/20
Greer N, Wilt T, Duan-Porter D, et al  | VA Evidence Synthesis Program
VA ESP
8/18/20
Silverberg J, Goldberg J, Weissman A | PROSPERO
8/18/20
Hoste L, Van Paemel R, Haerynck F | medRxiv
Aim: To perform a systematic review of published cases of this novel multisystem inflammatory syndrome in children associated with COVID-19. 
8/18/20
Yoon SH, Yang S, Cho H, et al  | PROSPERO
8/18/20
Gashaw T, Hagos B, Sisay M | PROSPERO
8/18/20
Marinaki S, Grigorakos K, Boletis I, et al  | PROSPERO
8/18/20
Sahebi A, Adibi A, Pirani D | PROSPERO
8/18/20
Danielli M, Tan B, Hu J | PROSPERO
8/18/20
Rezaei S, Peikanpour M, Dastan F | PROSPERO
8/18/20
Bennis I, Bennis N | PROSPERO
8/18/20
Gonsalves L, Kara E, Broutet N, et al  | PROSPERO
8/17/20
Regalado JA, Tayam MM | PROSPERO
8/17/20
Chatterjee K, Sagar P, Chatterjee R, et al  | PROSPERO
8/17/20
Viana da Silva D, de Jesus Branco SM, Delmiro dos Santos A | PROSPERO
8/17/20
Kawala BA, Kisangala E, Ndagire R, et al  | PROSPERO
8/17/20
Bolaji O | PROSPERO
8/17/20
Hagos B, Gashaw T, Sisay M | PROSPERO
8/17/20
Jafar A, Lasso A, Hutton B, et al  | PROSPERO
8/17/20
Parveen R, Mishra P, Bajpai R, et al  | PROSPERO
8/17/20
Zhan Z, Zhang S, Chen Z | PROSPERO
8/17/20
Varghese A, George G, Sharat VK | PROSPERO
8/17/20
Elsokary M, Elsawah H, Hany A, et al  | PROSPERO
8/17/20
Castillo-Perez M, Jerjes-Sanchez C, Paredes-Vazquez JG, et al  | PROSPERO
8/16/20
Zhang Q, Cao F, Ji G, et al. | Medicine
8/16/20
Yang Y, Zhang D, Zhou C, et al. | BMJ Open
8/15/20
Wang X, Xie P, Sun G, et al | Medicine
8/15/20
Jia H, Han Z, Zhang K, et al. | Medicine
8/15/20
Li M, Fan D, Wang X | Medicine
8/15/20
Zhang X, Cao D, Liu J, et al. | Medicine
CANDIDATE THERAPEUTICS
8/15/20
Wen D, Wu L, Dong Y | Medicine
8/15/20
Zhang Q, Cao F, Ji G, et al. | Medicine
8/15/20
Liang F, Dong L, Zhou L, et al. | Medicine
8/14/20
Tripathy S, Varghese P, Naik M, et al  | PROSPERO
8/14/20
Vilcassim MJR, Callahan A, Zierold K | PROSPERO
8/14/20
Sinaga GHP, Tjoa K, Sutanto RL, et al  | PROSPERO
8/14/20
Li G, Song Z, Xu S, et al  | PROSPERO
8/14/20
Chen Y, Jiang X | PROSPERO
8/14/20
Hill T, Baker M, Isherwood L, et al. | medRxiv
Aim: To identify putative COVID-19 treatments and identify the roles of immunomodulators and antivirals in disease management. 
8/14/20
Mohanty R, Meher BR, Padhy BM, et al  | PROSPERO
8/14/20
Stavrou M, Solomou S, Ioannou A, et al  | PROSPERO
8/14/20
Zhan Z, Zhang S, Chen Z | PROSPERO
8/14/20
Stuijfzand S, Deforges C, Sandoz V, et al. | BMC Public Health
Aim: To synthesize the evidence on the psychological impact of pandemics/epidemics on the mental health of HCPs, what factors predict this impact, and the evidence of prevention/intervention strategies to reduce this impact.
UPDATED
8/14/20
Bhattacharyya A, Sarma P, Kaur H, et al  | PROSPERO
8/14/20
Wu Z, Tang S | PROSPERO
8/14/20
Okwundu JO, Uthman O, Akah OZ | PROSPERO
8/14/20
Neal E, Russell F, Mulholland K | PROSPERO
8/14/20
Bassatne A, Basbous M, Chakhtoura M, et al  | PROSPERO
8/14/20
Asnakew S, Yitabarek GY | PROSPERO
8/14/20
Ao G, Wang Y, Qi X, et al  | PROSPERO
8/13/20
Arevalo Rodriguez I, Buitrago Garcia D, Simancas Racines D, et al.  | medRxiv
Aim: To review and critically appraise evidence about the proportion of RT-PCR false-negatives at initial testing for COVID-19. 
8/13/20
Lim ZJ, Subramaniam A, Reddy M, Jones D, et al  | PROSPERO
8/12/20
Thakkar S, Arora S, Kumar A, et al. | medRxiv
Aim: To provide a foundation for understanding the CV manifestations and outcomes of COVID-19.
8/12/20
Khorramizadeh M, Arab-bafrani Z, Mosavi E | PROSPERO
8/12/20
Chidambaram V, Tun NL, Haque W, et al. | medRxiv
Aim: To determine the demographic, clinical, laboratory and radiological factors associated with severity and mortality in COVID-19.
8/12/20
Sahoo KC, Pati S, Dash GC, et al  | PROSPERO
8/12/20
Chacko J, Brar G, Premkumar R | medRxiv
Aim: To evaluate the efficacy and safety of hydroxychloroquine among patients with COVID 19 infection.
8/12/20
de Oliveira JD, Lago MF, Sarandy MM, et al | PROSPERO
8/12/20
Lim JL, Subramaniam A | PROSPERO
8/12/20
Tunjungputri RN, Tetrasiwi EN, Rizqa T, et al  | PROSPERO
8/12/20
Ramos HMP, Franco ACD, Ronca D, et al  | PROSPERO
8/12/20
Tian Y, Chen H, Xie Y | PROSPERO
8/12/20
Sarkar S, Khanna P, Singh A | PROSPERO
8/12/20
Pickford R, Woeckel M, Schneider A, et al  | PROSPERO
8/12/20
Wells V, Thomas-Meyer M, Gentry S, et al  | PROSPERO
8/12/20
Sarma P, Bhattacharyya A, Kaur H, et al  | PROSPERO
8/12/20
Tractenberg SG, Viola TW, Grassi-Oliveira R | PROSPERO
8/12/20
Neil-Sztramko S, Dobbins M, Anderson L, et al  | PROSPERO
8/11/20
Batra K, Batra R, Sharma M, et al  | PROSPERO
8/11/20
Ismail S, Babonji A, Al Harbi S, et al  | PROSPERO
8/11/20
Honarmand K, Rochwerg B, Siemieniuk R, et al  | PROSPERO
8/11/20
Ayub A, Agarwal N, Mishra S | PROSPERO
8/11/20
Bhamani S, Lassi Z, Rashid M, et al  | PROSPERO
8/11/20
Yin TX, Luo Z | PROSPERO
8/11/20
Heneghan C, Spencer E, Brassey J, et al. | medRxiv
Aim: To identify and evaluate relevant articles (peer-reviewed or awaiting peer review) that examine the mode of viral transmission and ecological variables influencing the mode of transmission.
8/11/20
Campbell J, Bastos M, Perlman-Arrow S, et al  | PROSPERO
8/11/20
Michel S, von Ehrenstein O | PROSPERO
8/11/20
Yang L, Chen X | PROSPERO
8/11/20
Zaki N, Mohamed EA | medRxiv
Aim: To undertake a review and critical appraisal of all published/preprint reports that offer an estimation of incubation periods for novel coronavirus (COVID-19).
8/11/20
Yang J, Chen Y, Tian C, et al  | PROSPERO
8/10/20
Singh P, Pratap S, Bhoil R | PROSPERO
8/10/20
Yang L, Cao S, Huang J | PROSPERO
8/10/20
Sandoval C, Carrasco C, Carrasco D, et al  | PROSPERO
8/10/20
Mozaffari H, Darand M, Raeisi T, et al | PROSPERO
8/10/20
Ma H, Yang L, Guo H | PROSPERO
8/10/20
Necho M, Tsehay M, Belete A | PROSPERO
8/10/20
Henrina J, Pranata R | PROSPERO
8/10/20
Christol RO, Tinica G, Furnica C, et al  | PROSPERO
8/10/20
Sabe M, Dorsaz O, Kaiser S, et al  | PROSPERO
8/7/20
Wang X, Xie P, Sun G, et al | Medicine
8/7/20
Fantin K, Nelson T, Mehdi A | PROSPERO
8/7/20
Li Y, Xu Y, Shi P, et al. | Medicine
8/7/20
Qi M, Jones C, Li P, et al  | PROSPERO
8/7/20
Li R, Li Y, Li B, et al. | Medicine
8/7/20
Patell R, Chiasakul T, Bauer E, et al  | PROSPERO
8/7/20
Sheng Z, Zhang L, Liu X, et al. | Medicine
8/7/20
Henrina J, Pranata R, Lawrensia D, et al  | PROSPERO
8/7/20
Patel K, Huntley C, Mobeen F, et al  | PROSPERO
8/7/20
Gbinigie OA, Akyea RK | Wellcome Open Research
Aim: To critically appraise and evaluate the evidence for using zinc as prophylaxis and/or treatment for COVID-19.
8/7/20
Shi Y, Wen D, Wang H, et al. | Medicine
8/7/20
Medeiros G, Nunes A, Azevedo K, et al. | Medicine
8/7/20
Abdelaal A, Alkhatip AMM, Kamel MG, et al  | PROSPERO
8/7/20
Li Y, Xu H, Lang H, et al. | Medicine
8/7/20
Khanna P, Sarkar S, Singh A | PROSPERO
8/7/20
Gu R, Xu S, Li Z, et al. | Medicine
8/7/20
Li L, Chen X, Yang W, et al. | Medicine
8/7/20
Vardoulkis S | PROSPERO
8/6/20
Mendes NF, Jara CP, Mansour E, et al. | Research Square
Aim: To review the evidence on the description of asthma as a premorbid condition and its putative association with severe progression of the disease.
8/6/20
Henschke N, Villanueva G, Cogo E | PROSPERO
8/6/20
Wang J, Tang H | PROSPERO
8/6/20
Cui L, Cheng W, Chen M | PROSPERO
8/6/20
Veluri N | PROSPERO
8/6/20
Keegan D, Heffernan E, Masterson S | PROSPERO
8/6/20
AlvesVP, Casemiro FG, de Araujo BG, et al  | PROSPERO
8/6/20
Turner S, Botero N, Nino A, et al  | PROSPERO
8/6/20
Necho M, Belete A, Getachew Y | PROSPERO
8/6/20
Peeters E, Kaur Dhillon Ajit Sing S, Vandesompele J, et al. | medRxiv
Aim: To assess the diagnostic sensitivity of SARS-CoV-2 testing on saliva compared to NP swabs.
8/6/20
Sheng X, Zhou R, Tan Y | PROSPERO
8/6/20
Roshandel E, Kazemi MH, Dehaghi BK, et al. | Research Square
Aim: To explore the possible association of HScore parameters with severity in COVID-19 patients. 
8/6/20
Xu N, Li T, Huang M | PROSPERO
8/6/20
Fernandes N, Antunes M | PROSPERO
8/5/20
Ali R, Al-Jageka C, Bhasin A, et al  | PROSPERO
8/5/20
Li Y, Li J, Zhong D, et al. | Syst Rev
8/5/20
Liu X, Li X, Sun T, et al. | SSRN
Aim: To assess whether there are differences in clinical manifestations between COVID-19 patients from the East and the West.
8/5/20
da Cunha Sa Caputo D, Coelho de Oliveira AC, Sonza A, et al  | PROSPERO
8/5/20
Zhong Y, Wang K, Zhu Y, et al  | PROSPERO
8/5/20
Liu S, Cao Y, Zhi Y | PROSPERO
8/5/20
de Amaral LC, Calado RD, Teixeira AM, et al. | Research Square
Aim: To map how Lean tools are being used in healthcare and what are their results, including those related to humanization.
8/5/20
Udeh R, Majeed T, Manuel J | PROSPERO
8/5/20
Haile T, Mariye T, Gebremeskel G, et al  | PROSPERO
8/5/20
Khanna P, Sarkar S, Singh A | PROSPERO
8/5/20
Su K, Liu S, Li J, et al  | PROSPERO
8/5/20
Mansuri Z, Sharma K | PROSPERO
8/5/20
Zereabruk K, Aberhe W, Mebrahtom G, et al  | PROSPERO
8/5/20
Aberhe W, Hailay A, Zereabruk K, et al  | PROSPERO
8/5/20
Elsayed HH, Hassaballa AS, Ahmed TA, et al. | Research Square
Aim: To review the evidence on IMV for COVID-associated ARDS to study its outcome among different countries.
8/5/20
Yisak H, Ewunetei A, Teshome F, et al  | PROSPERO
8/4/20
Qian L  | PROSPERO
8/4/20
Patwary MM, Shuvo FK, Dendup T, et al  | PROSPERO
8/4/20
Chi C, Sun J | PROSPERO
8/4/20
Zhang X, Hong T, Lin L | PROSPERO
8/4/20
Lazarus G, Rinaldi I | PROSPERO
8/4/20
Routhier F, Lebrasseur A, Fortin-Bedard N, et al  | PROSPERO
8/4/20
Capucho H | PROSPERO
8/4/20
Deo KB, Shrestha R, Kumar-M P, et al  | PROSPERO
8/4/20
Dominic C, Bhalla G, Khare Y, et al  | PROSPERO
8/4/20
Jia N, Sun X, Wang Y, et al  | PROSPERO
8/4/20
Zhang H, Zhang H, Zhang X, et al  | PROSPERO
8/4/20
Kotepui M, Masangkay FR, Kotepui KU, et al  | PROSPERO
8/4/20
Aberhe W, Hailay A, Zereabruk K, et al  | PROSPERO
8/4/20
Hashemimadani N, Emami Z, Janani L, et al. | Research Square
Aim: To assess the relationship between different chest CT features and severity of clinical presentation in COVID-19.
8/3/20
Alves da Silva J, Capucho H | PROSPERO
8/3/20
Moya-Salazar J, Contreras-Pulache H, Moya-Espinoza J | PROSPERO
8/3/20
Miranda ML, Gabbai-Armelin P, Sales LS, et al  | PROSPERO
8/3/20
Perez Y, Li J, Tavernier E, et al  | PROSPERO
8/3/20
Zereabruk K, Aberhe W, Hailay A, et al  | PROSPERO
8/3/20
Furtado S, dos Santos Lucas AC, Basilio Carneiro AL, et al  | PROSPERO
8/3/20
Kyriazopoulou E, Giamarellos-Bourboulis E, Reinhart K, et al  | PROSPERO
8/3/20
Xiong X, Nie R | PROSPERO
8/3/20
Sirois F, Owens J | PROSPERO
8/2/20
Mahdi SS, Ahmed Z, Allana R, et al. | Research Square
Aim: To review all the relevant literate published so far on dental aspects of Covid-19 in order to serve as point of synthesis for future recommendations and guidelines for dental practices. 
8/2/20
Arab-zozani M, Hassanipour S, Ghoddoosi-Nejad D | BMJ Open
8/1/20
Salcher-Konrad M, Jhass A, Naci H, et al. | medRxiv
Aim: To synthesise early international evidence on mortality rates and incidence of COVID-19 among people who use and provide LTC. 
8/1/20
Madewell ZJ, Yang Y, Longini IM, et al. | medRxiv
Aim: To review the evidence on the spread of SARS-CoV-2 by direct, indirect, or close contact with infected people in indoor environments.
8/1/20
Fernandez Villalobos NV, Ott J, Klett-Tammen C | medRxiv
Aim: To review the evidence on the associations between comorbidities and behavioural factors with hospitalisation, Intensive Care Unit (ICU) admission, and death due to COVID-19.
7/31/20
Park M, Pawliuk C, Nguyen T, et al. | medRxiv
Aim: To identify the reported communicable period of SARS-CoV-2.
7/31/20
Szczepura A, Krishnan N, Gumber A, et al  | PROSPERO
7/31/20
Zhang Q, Jiang Y | PROSPERO
7/31/20
Lahiri D, Mondal R, Deb S, et al  | PROSPERO
7/31/20
Marzaleh MA, Ghahramani S | PROSPERO
7/31/20
Zhao X, Han G, Gang X | PROSPERO
7/31/20
Almaqbali M | PROSPERO
7/31/20
Darmarkusuma A, Nugroho DB, Chandra LA, et al  | PROSPERO
7/31/20
Browne M, Sing HH, Keith-Jopp CKJ, et al  | PROSPERO
7/30/20
Chivese T, Musa OAH, Hindy G, et al. | medRxiv
Aim: To synthesize the findings presented in systematic reviews and meta-analyses as well as to update the evidence using a meta-analysis in evaluating the efficacy and safety of CQ and HCQ with or without Azithromycin for the treatment of COVID19 infection.
7/30/20
Hu Y, Xiong J, Chen L, et al. | Research Square
Aim: To summarize the existing literature on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in newborns to clarify the clinical features and outcomes of neonates with COVID-19.
7/30/20
Zhao B, Liu K, Lei S, et al. | Research Square
Aim: To investigate the prevalence of elevated troponins in these patients and its prognostic value for predicting mortality.
7/30/20
Chivese T, Musa O | PROSPERO
7/29/20
Maidment I, Young E, Wong G, et al  | PROSPERO
7/29/20
Anderson L, Griffith L, Balion C | PROSPERO
7/29/20
Jaber M, Hassan A, AlQahtani F, et al  | PROSPERO
7/29/20
Mao Z, Ong ACM | PROSPERO
7/29/20
Oladimeji K, Dahman NBH, El Shahaway AES, et al  | PROSPERO
7/29/20
Grenet G, Mekhaldi S, Mainbourg S, et al. | medRxiv
Aim: To estimate the effect of DPP4 inhibitors on the risk of respiratory infections.
7/29/20
Menear M, Rice D | Universite Laval
7/29/20
Saez M, Barceli MA, Tobias A, et al  | PROSPERO
7/29/20
Miller J, Lee S | PROSPERO
7/29/20
Gupta A, Ng SM, Mouyis K, et al  | PROSPERO
7/29/20
Tirfe M, Berhane H, Teklu T | PROSPERO
7/29/20
Cevik M, Tate M, Lloyd O, et al. | medRxiv
Aim: To characterise viral load dynamics, duration of viral RNA, and viable virus shedding of SARS-CoV-2 in various body fluids and to compare SARS-CoV-2 viral dynamics with SARS-CoV-1 and MERS-CoV.
7/29/20
Gupta A, Ng SM, Mouyis K, et al  | PROSPERO
7/29/20
Siegel A | PROSPERO
7/29/20
Mayr V, Anna G, Gartlehner G, et al. | Research Square
Aim: To determine the frequency of CNS manifestations of COVID-19 (CNS symptoms, acute cerebrovascular disease, and infectious/inflammatory CNS diseases) and to summarize the current evidence for direct invasion of the CNS by SARS-CoV-2.
7/28/20
Pearce S, Cruz E, Brickley E, et al  | PROSPERO
7/28/20
A systematic review of the effectiveness of Acceptance and Commitment Therapy (ACT) compared with other psychological therapies in managing grief experienced by bereaved spouses or partners of adults who had received palliative care worldwide | PROSPERO
7/28/20
Mamuye M, Yisake H, Teshome F, et al  | PROSPERO
7/28/20
Hydoub YM, Nour S, Al Zubaidi AM | PROSPERO
7/28/20
Moursi A, Taha SHN, Ramadan A | medRxiv
Aim: To assess the cure rate, duration of hospital stay, radiological progression, clinical worsening, need for mechanical ventilation, the occurrence of side effects, and mortality. 
7/28/20
Coon JT, Whear R, Abbott R, et al  | PROSPERO
7/28/20
Pasin L, Landoni G | PROSPERO
7/28/20
Isaacs Z, Guinness L | PROSPERO
7/28/20
Alam MA, Patwary MM, Hossain MR, et al  | PROSPERO
7/28/20
Jomaa MK, Srour S, Geng Y, et al  | PROSPERO
7/28/20
Liu H, Yang D, Zou Y, et al  | PROSPERO
7/28/20
Ma Q, Wu L, Yang Z, et al  | PROSPERO
7/28/20
Qin Q, Chen B, Wang Y, et al  | PROSPERO
7/28/20
Alexandrina de Araujo T, Ferreira de Moura R, Oliveira de Almeida N | PROSPERO
7/28/20
Kiyumi MA, Kalhan A | PROSPERO
7/27/20
Tan RQ, Li WTV, Shum W, et al. | Research Square
Aim: To conduct a systematic review and meta-analysis of peer-reviewed articles, which described clinical data of smell disturbances and OD in COVID-19 patients.
7/27/20
Sales-Peres S, Azevedo-Silva L, Sales-Peres M | PROSPERO
7/27/20
Sardar S, Sharma R, Elshafei MN, et al  | PROSPERO
7/27/20
Syangtan G, Bista S, Dawadi P, et al. | Research Square
Aim: To appraise the burden of asymptomatic individuals and estimate their occurrence among different age groups and gender by reviewing the existing published data on asymptomatic people with COVID-19.
7/27/20
Mohamed MA, Cheng C, Xiang W | PROSPERO
7/27/20
Prado PAB, Vasquez AAH, Comande D, et al  | PROSPERO
7/27/20
Parry M, Bjornnes AK, Nickerson N, et al. | CIHR IRSC
Aim: To determine what is known about the mental health and wellbeing of family caregivers during communicable disease outbreaks.
7/27/20
Babata KL, Yeo KT, Chan CS, et al. | Cochrane Database of Systematic Reviews
7/27/20
Sales-Peres S, Azevedo-Silva L, Castilho AV, et al  | PROSPERO
7/27/20
Chan CS, Kong JY, Babata KL, et al. | Cochrane Database of Systematic Reviews
7/27/20
Goncalves PM, Cuccarese VHE, Cabrera AAC | PROSPERO
7/27/20
Desse TA, Barhane AM | PROSPERO
7/27/20
Zhang G | PROSPERO
7/27/20
Koizumi T, Sugimoto K, Ohnota S, et al  | PROSPERO
7/27/20
Huang X, Huang P, Zheng J, et al  | PROSPERO
7/27/20
Bayley H, Ayabina D, Hollingsworth TD | PROSPERO
7/25/20
Juneau CE, Briand AS, Pueyo T, et al  | medRxiv
Aim: To examine contact tracing effectiveness in the context of COVID-19.
7/25/20
Liu D, You Y, Chen Y, et al. | Medicine
7/25/20
Karimzadeh S, Bhopal R, Nguyen HT | Preprints
Aim: To review the literature on SARS-CoV-2 viral dynamics and their correlation with outcome.
7/24/20
Demis A, Getie A, Gedefaw, et al  | PROSPERO
7/24/20
Weeks R, Limaye R, Wahl B, et al  | PROSPERO
7/24/20
Van de Sande DGMM, Van Genderen ME, Huiskens J, et al  | PROSPERO
7/24/20
Tripathy S, Varghese P, Panda BB, et al | PROSPERO
7/24/20
Gomes Z, Aithal S, Antonipillai V, et al  | PROSPERO
7/24/20
Cheruiyot I, Sehmi P, Ngure B, et al  | PROSPERO
7/24/20
Stephenson A, Howes S, McDonough S, et al  | PROSPERO
7/24/20
Fathalipour M, Noormandi A, Hassanipour S | PROSPERO
7/24/20
Schneider J, Gibson B, Talamonti D, et al | PROSPERO
7/24/20
Lee Y, McIntyre R | PROSPERO
7/24/20
Gyanpuri V, Dhiman N, Pathak A, et al. | Research Square
7/24/20
Niburski K, Yan LR, Mamane S | PROSPERO
7/23/20
Yigezu A, Mengistu M, Mikuzie A | Research Square
Aim: To systematically review economic evaluation of interventions to respond to coronavirus pandemics in the global perspective.
7/23/20
Chambergo-Michilot D, Branez-Condorena A, Martinez-Rivera RN, et al | PROSPERO
7/23/20
Shukla P, Tiwari A, Ghosh A, et al  | PROSPERO
7/23/20
Wu G, Jiang P, Yuan H, et al. | Research Square
Aim: To evaluate the efficacy of N95 respirators and medical masks for protection against respiratory infectious diseases, including COVID-19.
7/23/20
Yuan X, Dongmei W, Mingying L, et al  | PROSPERO
7/23/20
Shaheed CA, Beardsley J, Saxena M, et al  | PROSPERO
7/23/20
Bzeizi K, Abdulia M, Mohammed N, et al. | Research Square
Aim: To assess the available evidence on the clinical effects of SARS-CoV-2 on liver function laboratory tests and coagulation profile in affected individuals. 
7/23/20
Sasongko TH, Kademane K, Cummins A, et al  | PROSPERO
7/23/20
Bae S, Kim SR, Park SM, et al  | PROSPERO
7/23/20
Santos J, de Holanda Agostinho AY, Ferreira Soares M, et al  | PROSPERO
7/23/20
Neria Espejo CA, da Silva Pedroso J, de Souza Godinho RC, et al  | PROSPERO
7/23/20
Diallo A, Diallo MH | PROSPERO
7/23/20
Thompson H, Mousa A, Dighe A, et al  | PROSPERO
7/23/20
Ali MM, Dahri M, Shrestha S, et al  | PROSPERO
7/23/20
Bolenta MT, Khatib Z, Asamoah BO, et al  | PROSPERO
7/23/20
Schmidt R, Genois R, Jin J, et al  | PROSPERO
7/23/20
Glendari G, Mangkuliguna G | PROSPERO
7/23/20
Mangkulinguna G, Glendari G | PROSPERO
7/23/20
Sugita B, Marchi R, Centa A, et al  | PROSPERO
7/23/20
Nurdiati D, Atthobari J, Nugroho D, et al  | PROSPERO
7/22/20
Fu Y, Zihan Y, Hanzhou L, et al  | PROSPERO
7/22/20
Qian K, Wang G, Peng H, et al. | Research Square
Aim: To review the evidence on the medical and clinical characteristics of the COVID-19 pandemic in China.
7/22/20
Strudwick G, Sockalingam S, Crawford A, et al. | CIHR IRSC
Aim: To review the evidence related to digital interventions that can be leveraged by the general population to support mental health during and after COVID-19.
7/22/20
Zhang T, Shui M, Zhou Y | PROSPERO
7/22/20
Puyat JH, Ahmad H, Avina M, et al. | CIHR IRSC
Aim: To investigate home-based activities that have protective and therapeutic effects against mental health symptoms during pandemics and to identify if there are activities that are effective for specific groups.
7/22/20
Arentz S, Khamba B, Mravunac M, et al  | PROSPERO
7/22/20
Zhan Q, Fan XJ, Lan YQ | PROSPERO
7/22/20
Zhang T, Shui M, Zhou Y | PROSPERO
7/22/20
Maged A, Dahab S | PROSPERO
7/22/20
Morley S, Bollard M | PROSPERO
7/22/20
Natolanda P, Quigley A | PROSPERO
7/22/20
Resende A, Almeida IB, Gomes IA, et al  | PROSPERO
7/22/20
Bethell J, Babineau J, Bretzlaff M, et al. | CMH Initiative
Aim: To review the evidence on social connectedness and mental health for residents of long-term care homes during the COVID-19 pandemic.
7/22/20
Zhang G, Yao X, Zhang L | PROSPERO
7/21/20
Sarfraz A, Sarfraz Z, Pervaiz Z, et al  | PROSPERO
7/21/20
Khurana R, Deshpande A, Pandey N, et al  | PROSPERO
7/21/20
Kanjanabuch T, Pongpirul K, Nopsopon T, et al  | PROSPERO
7/21/20
Souresrafil A, Rezapour A | PROSPERO
7/21/20
Sadeghi Z, Bahramnezhad F, Javadinejad M, et al  | PROSPERO
7/21/20
Wood F, Roe T, Newman J, et al  | PROSPERO
7/21/20
Zhou P, Zhao R, Zhang Y, et al  | PROSPERO
7/21/20
Grimani A, Bonell C, Michie S, et al  | PROSPERO
7/21/20
Aslam MS, Kim YJ, Qian L  | PROSPERO
7/21/20
Dhouib W, Ayouni I | PROSPERO
7/21/20
Zhong BL | PROSPERO
7/21/20
Wang Z, Xie J, Jiang M, et al  | PROSPERO
7/21/20
Hugo de Oliveira VH, de Albuquerque Filho JB, Morais de Azevedo KP, et al  | PROSPERO
7/20/20
Parashar S, Karthik AR, Gupta R | PROSPERO
7/20/20
Zheng X, Li Y, Yue P, et al  | PROSPERO
7/20/20
Keikha M, Kelishadi R, Akbari N, et al  | PROSPERO
7/20/20
Hokama P, Hojama NK, Nunes-Nogueira V | PROSPERO
7/20/20
Eketunde A, Adeosun A, Lawal O, et al  | PROSPERO
7/20/20
Videla A, Casetta B, Gospodinoff N, et al  | PROSPERO
7/20/20
Thomas B, Pallivalapila A, El Kassem W, et al. | Syst Rev
7/20/20
Veazie S, O'Neil M, LaFavor B, et al  | PROSPERO
7/20/20
Barth de Castro AC, Parlow JM, Martins CM, et al  | PROSPERO
7/20/20
Esmaeili M, Abdi F, Shafiee G, et al. | Research Square
Aim: To systematically review and pool all available evidence on the olfactory and gustatory dysfunction in COVID-19 patients. 
7/20/20
Li YC, Tu YK | PROSPERO
7/20/20
Wang C, Xaio S, Sun Y, et al. | Research Square
Aim: To examine the impact of respiratory infectious disease pandemics in the new millennium on mental health, behavioral responses, and parenting practices in children, and provide further intervention directions to mitigate negative effects of the 2019 novel coronavirus disease (COVID-19).
7/20/20
Arevalo-Rodriguez I, Seron P, Buitrago-Garcia D, et al. | SSRN
Aim: To collate and delineate current worldwide recommendations about the role and applications of tests to control SARS-CoV-2/COVID-19.
7/20/20
Fernandez Villalobos NV, Vanella P, Lange B | PROSPERO
7/20/20
Zhang G, Qi X, An Y | PROSPERO